| a newly isolated avian sarcoma virus, asv-1, carries the crk oncogene. | avian sarcoma virus 1 (asv-1) was isolated from a spontaneous sarcoma of an adult chicken. it is a replication-defective virus that induces fibrosarcomas in young chickens and oncogenic transformation in cultured chick embryo fibroblasts. the asv-1 genome has been cloned in the lambda gt wes.lambda b vector from closed circular viral dna extracted from infected cells. the nucleotide sequence of the oncogene insert in the asv-1 genome has been determined. it is virtually identical to the sequence ... | 1989 | 2554234 |