a primate model for viral hemorrhagic fever. | lymphocytic choriomeningitis virus strain we (lcmv-we), a risk group 3 virus, causes a disease in rhesus monkeys that closely resembles human infection with lassa fever virus, a risk group 4 agent. three stages of disease progression have been defined and profiled in this model: pre-viremic, viremic, and terminal. the earliest or pre-viremic stage reveals changes in the blood profile predictive of the later stages of disease. in order to identify whether specific changes are pathognomonic, it wa ... | 2018 | 28986843 |