| isfahan virus, a new vesiculovirus infecting humans, gerbils, and sandflies in iran. | the characteristics and ecology of isfahan virus, a new vesicular stomatitis virus (vsv) serotype, are described. two strains of the agent were isolated from pools of phlebotomus papatasi collected in iran in 1975. its animal pathogenicity, growth rate, cytopathic effect, and plaque morphology are similar to those of the other vsv serotypes. electron microscopic examination of the virus demonstrated a bullet shape, the presence of truncated particles and maturation at plasma membranes. antigenic ... | 1977 | 192094 |
| [experimental myocarditis in albino mice induced by piry virus (bean 24232). anatomo-pathological study using optical microscopy and electron microscopy with demonstration of viral particles]. | | 1978 | 675030 |
| vertical transmission of the piry rhabdovirus by sigma virus-infected drosophila melanogaster females. | piry rhabdovirus is not transmitted from drosophila melanogaster females to their progeny. however, in mixed infections with sigma, another rhabdovirus, bearing the g+ genetic marker, piry may occasionally be transmitted to offspring. thus, an endemic drosophila virus can act as a helper virus enabling vertical transmission of a virus pathogenic to vertebrates. | 1989 | 2499659 |
| [research on antibodies to arbovirus in the serum of residents of the village of corte de pedra, valencia, bahia]. | a serological survey for research on antibodies to arbovirus was carried out on 288 residents of the rural zone of the village of corte de pedra, valença, bahia. it was observed that 3.8% of the sample population presented hi and n antibodies against flaviviruses (ilhéus 6, st. louis 2, yellow fever 3 and rocio 1). one person, who had previously lived in the amazon region, had antibodies to mayaro. the authors were unable to detect either n antibodies for piry virus in a random sample of 75 pers ... | 1986 | 3613976 |
| characterization of piry virus. | | 1970 | 4097557 |
| susceptibility of various animals to the vesiculovirus piry. | to determine the pathogenic potential of the vesiculovirus piry for domestic animals, two ponies, two steers, three sheep, three goats and three pigs were inoculated intradermally in the tongue or, in the case of the pigs, in the snout, heel and coronary band. inoculated animals were housed in one room and allowed to mingle freely with an equal number of uninoculated contact animals of each species. clinical signs of infection, consisting of elevated temperature and ulcers at the inoculation sit ... | 1984 | 6747282 |
| [arboviruses. xvii - experimental effect of piry virus on malnourished mice]. | | 1981 | 6814290 |
| [ultrastructural lesions of the brain in albino mice experimentally inoculated with piry virus (bean 24232)]. | | 1981 | 7323604 |
| diagnosis of brazilian vesiculoviruses by reverse transcription-polymerase chain reaction. | we describe a reverse transcription-polymerase chain reaction (rt-pcr) and a nested-pcr for diagnosis of piry, carajás, cocal, and alagoas vesiculoviruses from brazil. the rna extracts of viral and clinical samples were submitted to a rt-pcr using vesiculovirus g primers that amplify part of the glycoprotein gene. the rt-pcr produced amplicons of expected size, 290 base pair, for the four studied viruses. the rt-pcr showed a high sensitivity being 151.3 times (2.18 log) more sensitive for the de ... | 2005 | 16021308 |
| influence of enriched environment on viral encephalitis outcomes: behavioral and neuropathological changes in albino swiss mice. | an enriched environment has previously been described as enhancing natural killer cell activity of recognizing and killing virally infected cells. however, the effects of environmental enrichment on behavioral changes in relation to virus clearance and the neuropathology of encephalitis have not been studied in detail. we tested the hypothesis that environmental enrichment leads to less cns neuroinvasion and/or more rapid viral clearance in association with t cells without neuronal damage. stere ... | 2011 | 21264301 |
| complete genome sequence of piry vesiculovirus. | piry virus (piryv) is a rhabdovirus (genus vesiculovirus) and is described as a possible human pathogen, originally isolated from a philander opossum trapped in para state, northern brazil. this study describes the complete full coding sequence and the genetic characterization of piryv. the genome sequence reveals that piryv has a typical vesiculovirus-like organization, encoding the five genes typical of the genus. phylogenetic analysis confirmed that piryv is most closely related to perinet vi ... | 2016 | 27216928 |
| three-dimensional morphometric analysis of microglial changes in a mouse model of virus encephalitis: age and environmental influences. | many rna virus cns infections cause neurological disease. because piry virus has a limited human pathogenicity and exercise reduces activation of microglia in aged mice, possible influences of environment and aging on microglial morphology and behavior in mice sublethal encephalitis were investigated. female albino swiss mice were raised either in standard (s) or in enriched (ee) cages from age 2 to 6 months (young - y), or from 2 to 16 months (aged - a). after behavioral tests, mice nostrils we ... | 2015 | 25980955 |
| viral contamination during sequential phacoemulsification surgeries in an experimental model. | to determine the incidence of piry virus contamination among surgical instruments used with disposable accessories for phacoemulsification during sequential surgeries. | 2012 | 22872199 |
| reviewing host proteins of rhabdoviridae: possible leads for lesser studied viruses. | rhabdoviridae, characterized by bullet-shaped viruses, is known for its diverse host range, which includes plants, arthropods, fishes and humans. understanding the viral-host interactions of this family can prove beneficial in developing effective therapeutic strategies. the host proteins interacting with animal rhabdoviruses have been reviewed in this report. several important host proteins commonly interacting with animal rhabdoviruses are being reported, some of which, interestingly, have mo ... | 2011 | 22116291 |
| bioinformatics comparison of g protein of isfahan virus with the same proteins of two other closely related viruses of the genus vesiculovirus. | since there are not much experimental data available about different structural properties of isfahan virus (isfv), in the present investigation, computational study of g protein of isfv was performed and the results were compared with g proteins of chandipura virus (chpv) and piry virus (pv). calculation of amino acid compositions of g proteins of viruses was done by pseaac server. predictions of localization, sequence of signal peptides, c, n and o glycosylation sites, transmembrane helices, c ... | 2009 | 19508221 |
| complete genome sequences of chandipura and isfahan vesiculoviruses. | chandipura virus (chpv) and isfahan virus (isfv) are two members of the genus vesiculovirus from asia. both are arthropod-transmitted and are able to infect humans, but neither causes vesicular stomatitis in livestock. the complete genome sequence for each virus has been determined. the negative-sense rna genome comprises 11,119 nt (chpv) or 11,088 nt (isfv). the most variable of the non-transcribed regions is the intergenic spacer at the g-l gene junction (4 bases in isfv, 20 in chpv). phylogen ... | 2004 | 15614433 |
| the relationship of piry virus to other vesiculoviruses: a re-evaluation based on the glycoprotein gene sequence. | by sequencing the 3 half of the piry virus genome, we show that piry virus, like the other vesiculoviruses, contains the genes for nucleoprotein n, phosphoprotein p, matrix protein m, glycoprotein g and polymerase protein l, in that order. our analysis of the piry g protein sequence suggests that piry and chandipura are related to each other as closely as the indiana and new jersey vesicular stomatitis virus serotypes are to each other. a re-examination of amino acid sequences in the nucleocapsi ... | 1995 | 8724858 |
| molecular diversity of the lyssavirus genus. | the sequence of 5568 nucleotides of the 3' moiety of the mokola virus genome (serotype 3 of lyssaviruses) encompassing the nucleoprotein (n), phosphoprotein, matrix protein, and glycoprotein genes is presented and compared to that of the vaccinal strains of serotype 1. it allowed us to determine consensus sequences derived from the transcriptional start/stop signals and the order of protein conservation (nucleoprotein > matrix protein > phosphoprotein) in lyssaviruses. the sequences of the n gen ... | 1993 | 8386891 |
| piry virus antibodies in inhabitants of rio de janeiro. | | 1993 | 8139469 |
| structural and antigenic analysis of the nucleoprotein of bovine ephemeral fever rhabdovirus. | the nucleotide sequence of the bovine ephemeral fever virus (befv) genome has been determined from the 3' terminus to the end of the nucleoprotein (n) gene. the 3' leader sequence comprises 50 nucleotides and shares a common terminal three nucleotides (3'-ugc-) and a downstream u-rich domain with vesicular stomatitis virus (vsv) and rabies virus. the n gene comprises 1328 nucleotides from the transcription initiation consensus sequence (aacagg) to the conserved transcription termination-poly(a) ... | 1994 | 8046391 |
| role of fatty acid acylation of membrane glycoproteins. absence of palmitic acid in glycoproteins of two serotypes of vesicular stomatitis virus. | the presence of fatty acids bound to the glycoprotein in a number of serotypes of vesicular stomatitis virus was investigated by growing the virus in the presence of [3h]palmitic acid. [3h]palmitate was efficiently incorporated into g proteins of the serotypes indiana, piry, and chandipura but was not detected in g proteins from cocal and three different strains of new jersey serotypes. cerulenin, an inhibitor of fatty acid acylation, also did not inhibit the maturation of cocal serotype. these ... | 1984 | 6325406 |
| sequence determination of the (+) leader rna regions of the vesicular stomatitis virus chandipura, cocal, and piry serotype genomes. | using 3'-end-labeled genome probes, cells infected with vesicular stomatitis virus chandipura, cocal, and piry serotypes were shown to contain (+) leader rnas of approximately 50 nucleotides in length. the nucleotide sequence of the leader rna regions of these genomes was determined and compared with the previously reported sequences of both the (+) and (-) leader rna regions of other vesicular stomatitis virus serotypes. regions of strong conservation of nucleotide sequence among the various ve ... | 1983 | 6298450 |
| rna transcription by the virion polymerases of five rhabdoviruses. | the presence of a virion-associated rna-dependent rna polymerase in five serologically distinct rhabdovirus isolates (vesicular stomatitis virus [vsv] indiana, vsv new jersey, cocal, chandipura, and piry viruses) has been demonstrated. the enzyme for each virus has been shown to be a transcriptase capable of synthesizing in vitro rna which is complementary to the viral genome. by sequence analyses it has been shown that, for each rhabdovirus, transcription is multiply initiated with specific 5' ... | 1974 | 4362867 |
| [a genetic study of the interaction of piry virus with drosophila]. | piry virus mutants selected for altered growth properties in drosophila melanogaster have previously been designated agd mutants. this paper presents a classification scheme for grouping some of these mutants and also presents the characteristics of some members of each group. analysis, for each agd clone, of the mean incubation time at 20 degrees c relative to the mean incubation time at 28 degrees c (t20,t28), compared to the range of similar data for wild-type virus enabled us to define 4 cla ... | 1991 | 1796217 |
| the sequence of the nucleocapsid protein (n) gene of piry virus: possible domains in the n protein of vesiculoviruses. | a number of independent cdna clones of the piry virus n gene message were identified and sequenced. from the resulting sequences and previously published data, we derived the sequence of the mrna for this protein. sequence similarities of the translated region of piry virus with that of other viruses suggest that piry virus is as distantly related to chandipura virus as it is to the vesicular stomatitis viruses of indiana and new jersey serotypes. based on the relative conservation of the amino ... | 1990 | 1698928 |
| the co2 sensitivity induced by two rhabdoviruses, piry and chandipura, in drosophila melanogaster. | piry and chandipura viruses induce co2 sensitivity after multiplication in d. melanogaster. flies infected with piry virus react to co2 like flies infected with sigma virus: after a post-infection delay the flies become sensitive; sister batches exposed later on remain persistently co2 sensitive. flies infected with chandipura virus react to co2 like flies infected with vsv: flies become sensitive, but sister batches exposed later on recover and fail to show any co2 sensitivity, although they re ... | 1975 | 813550 |
| proteins of vesicular stomatitis virus. v. identification of a precursor to the phosphoprotein of piry virus. | a metabolic precursor to the major phosphoprotein of piry virus (nsv) has been identified in extracts of piry virus-infected l cells. the conversion of the precursor nsi to nsv occurs with a half-life of 20 min and is independent of continued protein synthesis. nsi has a greater electrophoretic mobility on sodium dodecyl sulfate-polyacrylamide gel electrophoresis than does the product nsv, suggesting an increase in molecular weight during maturation. the conversion is unaffected by cyclic amp, c ... | 1979 | 225529 |
| virus infections on prion diseased mice exacerbate inflammatory microglial response. | we investigated possible interaction between an arbovirus infection and the me7 induced mice prion disease. c57bl/6, females, 6-week-old, were submitted to a bilateral intrahippocampal injection of me7 prion strain (me7) or normal brain homogenate (nbh). after injections, animals were organized into two groups: nbh (n = 26) and me7 (n = 29). at 15th week after injections (wpi), animals were challenged intranasally with a suspension of piry arbovirus 0.001% or with nbh. behavioral changes in me7 ... | 2016 | 28003864 |