| nucleotide sequence of the envelope glycoprotein of negishi virus shows very close homology to louping ill virus. | negishi virus, a member of the family flaviviridae, was originally isolated in japan, during an outbreak of japanese encephalitis. antigenically, however, negishi virus resembles the tick-borne rather than the mosquito-borne flaviviruses. monoclonal antibodies that bind louping ill virus showed a close antigenic relationship between louping ill and negishi virus. the genes encoding the envelope glycoprotein of negishi virus (strain 3248/49/p10) and louping ill virus (strain sb526) were cloned an ... | 1992 | 1326816 |
| enhanced neutralization of flavivirus by monoclonal antibodies against negishi virus. | ten monoclonal antibodies against negishi virus were classified into 3 groups and 7 types according to the reaction patterns to negishi virus by the hemagglutination inhibition (hi) test and by several kinds of neutralization tests. when kinetic neutralization was applied to these monoclonal antibodies at the same hi titer of 1:64, the initial slope and the persistent fraction of the kinetic curve was varied in each antibody. in the double-kinetic neutralization test, neutralization did not proc ... | 1988 | 3393099 |
| [isolation of strains of negishi virus in khabarovsk territory]. | two virus strains isolated from aedes vexans nipponi and aedes vexans vexans in 1976 and 1978, respectively, in khabarovsk territory were identified as negishi virus. among 176 human sera, 22.7% were found to contain complement-fixing antibodies to negishi virus soluble antigen. | 1987 | 3554754 |
| antigenic analysis of flaviviruses with monoclonal antibodies against negishi virus. | twelve monoclonal antibodies against negishi virus were obtained and characterized by hemagglutination inhibition (hi) and neutralization (nt) tests using five flaviviruses isolated in the pan-pacific region. the reaction pattern of the antibodies showed that negishi virus was most closely related to langat virus, followed by 3-arch, je and apoi viruses in that order. hemagglutinating (ha) antigen of the virus had distinct hi relating sites which were negishi virus specific, tick borne encephali ... | 1984 | 6096680 |
| phylogeny of the genus flavivirus. | we undertook a comprehensive phylogenetic study to establish the genetic relationship among the viruses of the genus flavivirus and to compare the classification based on molecular phylogeny with the existing serologic method. by using a combination of quantitative definitions (bootstrap support level and the pairwise nucleotide sequence identity), the viruses could be classified into clusters, clades, and species. our phylogenetic study revealed for the first time that from the putative ancesto ... | 1998 | 9420202 |
| [a recombinant adenovirus expressing the ns1 nonstructural protein of tick-borne encephalitis virus: some characteristics of the immunologic basis of antiviral action]. | recombinant adenovirus expressing ns1 nonstructural protein of trick-borne encephalitis (tbe) virus (rad 51) protected mice from many strains of tbe and omsk hemorhagic fever (ohf) viruses, but virtually did not protect them from negishi virus. during combined use of whole-virion inactivated tbe vaccine and rad 51 the recombinant adenovirus notably potentiated the protective effect of the traditional vaccine. the results of adaptive transfer of immunological material from mice infected with rad ... | 1997 | 9424847 |
| the identification of negishi virus, a presumably new member of russian spring-summer encephalitis virus family isolated in japan. | | 1961 | 14481659 |
| universal primers that amplify rna from all three flavivirus subgroups. | species within the flavivirus genus pose public health problems around the world. increasing cases of dengue and japanese encephalitis virus in asia, frequent outbreaks of yellow fever virus in africa and south america, and the ongoing spread of west nile virus throughout the americas, show the geographical burden of flavivirus diseases. flavivirus infections are often indistinct from and confused with other febrile illnesses. here we review the specificity of published primers, and describe a n ... | 2008 | 18218114 |
| zoonotic encephalitides caused by arboviruses: transmission and epidemiology of alphaviruses and flaviviruses. | in this review, we mainly focus on zoonotic encephalitides caused by arthropod-borne viruses (arboviruses) of the families flaviviridae (genus flavivirus) and togaviridae (genus alphavirus) that are important in both humans and domestic animals. specifically, we will focus on alphaviruses (eastern equine encephalitis virus, western equine encephalitis virus, venezuelan equine encephalitis virus) and flaviviruses (japanese encephalitis virus and west nile virus). most of these viruses were origin ... | 2013 | 24427764 |
| flavidb: a data mining system for knowledge discovery in flaviviruses with direct applications in immunology and vaccinology. | the flavivirus genus is unusually large, comprising more than 70 species, of which more than half are known human pathogens. it includes a set of clinically relevant infectious agents such as dengue, west nile, yellow fever, and japanese encephalitis viruses. although these pathogens have been studied extensively, safe and efficient vaccines lack for the majority of the flaviviruses. | 0 | 25544857 |
| louping ill in goats, spain, 2011. | although louping ill affects mainly sheep, a 2011 outbreak in northern spain occurred among goats. histopathologic lesions and molecular genetics identified a new strain of louping ill virus, 94% identical to the strain from britain. surveillance is needed to minimize risk to domestic and wildlife species and humans. | 0 | 22607689 |
| [oligopeptide mapping of viruses of the tick-borns encephalitis complex]. | comparison of oligopeptide maps of several viruses from the tick-borne encephalitis complex revealed considerable similarity between them manifested in the presence of a common oligonucleotide framework. at the same time there are differences between viruses, each of them having its own oligopeptides lacking in other viruses. the viruses under comparison form groups: tick-borne encephalitis viruses proper, langat and powassan viruses, negishi virus, louping-ill virus. within the group of tick-bo ... | 2016 | 7257319 |
| pathogenicity of negishi virus in mice characterized by age of susceptibility, routes of inoculation and growth of the virus in tissues. | | 1983 | 6865166 |