| evidence for a new rotavirus subgroup in india. | monoclonal antibodies specific for rotavirus subgroup 1 (sg1) and subgroup 2 (sg2) were used to analyse by enzyme immunoassay (eia) the subgroups of human rotavirus isolates obtained from three different parts of india during the period september 1985 to july 1987. we identified one isolate which failed to react with either sg1 or sg2 specific monoclonal antibodies, although it reacted well with a monoclonal antibody specific for group a rotaviruses. this finding suggests that it belongs to a ne ... | 1989 | 2544441 |
| paediatric gastroenteritis in the eastern malaysian state of sarawak: an epidemiological and clinical study. | over a period of 2 months, 35 of 69 (51%) cases of juvenile diarrhoea studied in eastern malaysia were associated with rotavirus excretion; rotavirus associated diarrhoea occurred most commonly in the 6-24 month age group. polyacrylamide gel electrophoresis (page) of genome ribonucleic acid showed that only 4 rotavirus electropherotypes could be detected. of those, 2 predominated and 2 were detected only once each; one of these may have been a reassortment of the two predominant electropherotype ... | 1988 | 2855768 |
| clinical and epidemiological features of acute infantile gastroenteritis associated with human rotavirus subgroups 1 and 2. | during a prospective 1-year study rotavirus isolates from 169 children with gastroenteritis were investigated by polyacrylamide gel electrophoresis. a total of 118 (70%) of the strains analyzed contained sufficient viral nucleic acid to give visible electrophoretic patterns; 36% were identified as strains belonging to subgroup 1 (short patterns), and 64% were identified as strains belonging to subgroup 2 (long patterns). the two subgroups cocirculated at equal frequencies during the first 7 mont ... | 1986 | 3007567 |
| protection of infants against rotavirus diarrhoea by rit 4237 attenuated bovine rotavirus strain vaccine. | a randomised, double-blind, placebo-controlled trial was conducted to evaluate the ability of rit 4237 live attenuated bovine rotavirus (subgroup 1) vaccine strain to protect against natural rotavirus infection in children. 178 infants aged 8 to 11 months received a single oral dose of rit 4237 vaccine or placebo and were followed up serologically and clinically during a subgroup 2 rotavirus epidemic. no side-effects attributable to the vaccine were observed. during the 5 months' observation aft ... | 1984 | 6143964 |
| isolation of human rotavirus subgroups 1 and 2 in cell culture. | one strain of human rotavirus subgroup 1 (kun) and one strain of subgroup 2 (mo) were isolated with the ma104 cell line, a fetal rhesus monkey kidney cell line. their subgroup specificities and rna patterns were identical to those of rotaviruses present in stools before cultivation. distinct cytopathic effects consisting of obscure cell boundaries, cell fusion, cell rounding, cell detachment, and lytic foci were recognized at passage 3 of mo and passage 6 of kun. no differences in cytopathic cha ... | 1982 | 6296195 |