| action of quail and chicken interferons on a quail cell line, qt35. | production of interferon (ifn) in quail cells (qt35) and the activity of quail ifn and heterologous avian ifn (chicken) on qt35 cells were examined. quail cells produced ifn after induction by bluetongue virus serotype 10; chicken and quail ifn conferred antiviral resistance on the quail cells. both chicken and quail ifn induced increased levels of 2',5'-oligoadenylate synthetase (2',5'-oas) in qt35 cells and reduced levels of intracellular salmonella typhimurium postchallenge. these results ind ... | 1995 | 7543005 |
| host defense responses associated with experimental hemorrhagic disease in white-tailed deer. | our objectives were to examine the immunity conferred by epizootic hemorrhagic disease virus serotype 2 (ehdv-2) infection in white-tailed deer (odocoileus virginianus) and determine if this immunity was protective during challenge with homologous (ehdv-2) or heterologous (bluetongue virus serotype 10; btv-10) virus. trials were conducted in the fall of 1992 and 1993. in the first experiment, naive white-tailed deer were infected intradermally and subcutaneously with ehdv-2 and monitored via phy ... | 1997 | 9249705 |
| selective in vitro cytotoxic effect of human cancer cells by bluetongue virus-10. | bluetongue viruses (btvs) infect primarily domestic cattle and wild ruminants but have never been shown to infect normal human cells. thus, humans are sero-negative towards btvs. the selective and differential effects of btv serotype 10 (btv-10) infection were investigated with five cell lines including primary human embryo lung fibroblast (hel) and primary murine embryos fibroblast(mef), human hepatic carcinoma 3b cell line (hep-3b), human lung carcinoma cell line (a549) and mouse fibroblast ce ... | 2008 | 17851866 |