| feline panleukopaenia virus and mink enteritis virus. a serological study. | | 1977 | 66862 |
| antigenic relationship of the feline infections peritonitis virus to coronaviruses of other species. | utilizing the direct and indirect fluorescent antibody procedure, the antigenic relationship of the feline infectious peritonitis virus (fipv) to 7 other human and animal coronaviruses was studied. fipv was found to be closely related to transmissible gastroenteritis virus (tgev) of swine. transmissible gastroenteritis virus and fipv were in turn antigenically related to human coronavirus 229e (hcv-229e) and canine coronavirus (ccv). an interesting finding in the study was that the 8 coronavirus ... | 1978 | 81044 |
| studies on the growth of feline panleukopaenia virus in cell cultures. | the growth of feline panleukopaenia virus was examined in relation to various cell growth curves of secondary feline kidney cells. in cell cultures with a high mitotic index, the manifestation of virus infection, expressed as percentage number of cells with inclusion bodies, was correspondingly high. in cultures with low mitotic index, the percentage number of cells with inclusion bodies was low. a cytopathic effect was seen by inoculation of virus with a titre of 10-3-5tcid-50/ml. this effect w ... | 1975 | 168729 |
| histopathology of feline panleukopenia in domestic cats. | histopathological observations were carried out on 17 domestic cats naturally affected with feline panleukopenia. principal lesions were found in the intestine, bone marrow, and lymphoid organs. intestinal lesions were characterized by degenerative changes accompanied by the appearance of intranuclear inclusion bodies in the epithelial cells of the crypts. in contrast to the crypts, the villi were seldom involved. hypoplasia, parenchymal degeneration, and activation of the reticuloendothelial sy ... | 1975 | 170544 |
| feline panleukopenia in japan. ii. hemagglutinability of the isolated virus. | | 1975 | 172687 |
| studies on feline panleukopenia. i. isolation and properties of virus strains. | | 1975 | 172688 |
| seasonality, natality and herd immunity in feline panleukopenia. | feline panleukopenia (fpl) was diagnosed in 185 of 7043 feline admissions (2.63%) at a university veterinary hospital over an eight-year period. flp has a distinct seasonal pattern, occurring during july, august and september. seasonal peaks were noted in all the years studied. cats less than one year of age accounted for 70% of the total morbidity. the birth of felines in the united states also assumes a distinctly seasonal pattern. analysis of 47,786 purebred litters born during 1970-1972 reve ... | 1976 | 174425 |
| evaluation of 6-azauridine and 5-iododeoxyuridine in the treatment of experimental viral infections. | the potential antiviral activity of 6-azauridine and 5-iododeoxyuridine was evaluated in a coordinated study at five institutions. experimental models in five species, the mouse, rabbit, swine, cat, and ferret, were established with use of 10 viruses: herpesvirus hominis types 1 and 2, murine cytomegalovirus, vaccinia virus, shope fibroma virus, transmissible gastroenteritis virus, swine influenza virus, feline viral rhinotracheitis virus, feline panleukopenia virus, and ferret distemper virus. ... | 1976 | 180189 |
| feline panleukopenia in japan. iii. propagation of the virus in cat kidney cell cultures. | | 1976 | 181626 |
| the parvoviruses. | | 1976 | 181899 |
| persistence of antibody to feline panleucopaenia induced by a modified live virus vaccine. | | 1976 | 184348 |
| fine structure of epithelial cells of lieberkühn's crypts in feline panleukopenia. | electron microscopic observation was carried out on epithelial cells of lieberkühn's crypts of cats naturally affected with feline panleukopenia. the most important change was the replication of feline panleukopenia. the most important change was the replication of feline panleukopenia virus in the nucleus with associated alterations in the lining epithelial cells of the crypts. in these cells in the early stage of infection, virus particles 20 nm in average diameter were found either singly or ... | 1976 | 189222 |
| morphology of feline kidney culture cells infected with feline panleukopenia virus. | | 1977 | 196223 |
| [antigenic relationships between feline infectious peritonitis (fip) and transmissible gastroenteritis (tge) viruses in swine]. | | 1977 | 200217 |
| an attenuated mink enteritis virus and its use in a trivalent vaccine: studies on safety and antigenicity. | | 1977 | 200331 |
| growth of an autonomously replicating parvovirus (feline panleukopenia): kinetics and morphogenesis. | | 1978 | 208485 |
| feline infectious peritonitis virus. ii. propagation in suckling mouse brain. | | 1978 | 211754 |
| pathogenesis of feline panleukopenia. | | 1978 | 212405 |
| studies on feline panleukopenia. ii. antigenicities of the virus. | | 1978 | 212633 |
| use of vaccines in exotic species. | | 1979 | 222041 |
| diagnostic exercise. cerebellar ataxia. | | 1979 | 222957 |
| the efficacy of two commercial feline rhinotracheitis-calicivirus-panleukopenia vaccines. | the efficacy of two commercial feline vaccines was determined by challenging vaccinated and unvaccinated cats sequentially with a virulent feline calicivirus and rhinotracheitis virus. serological responses to these viruses as well as to panleuk openia virus were also measured. results show significant protection and satisfactory serological responses are conferred by both vaccines. one vaccine showed significant superiority in protection against feline viral rhinotracheitis. | 1979 | 232426 |
| immunisation against panleukopenia: early development of immunity. | the time necessary to obtain the immunity of cats against panleukopenia has been studied by means of a modified live vaccine. this vaccine makes it possible to obtain a very early post-vaccinal immunity: the full immunity is reached 72 hr after the inoculation of the vaccine by the subcutaneous route. furthermore, we have demonstrated that a sensitive kitten can be admitted in a contaminated environment immediately after vaccination without showing any clinical evidence of the disease. | 1979 | 233781 |
| canine hemorrhagic enteritis: detection of viral particles by electron microscopy. | at necropsy, several dogs which died showing symptoms of hemorrhagic diarrhea, had significant lesions of the mucosa that were found especially in the duodenum and upper part of the small bowel. study of ultrathin sections from the diseased mucosa revealed particles resembling parvoviruses in altered nuclei of cells of the intestinal crypts. electron microscopic examination of intestinal contents by negative staining has shown the presence of many viral particles which have a diameter of 24 nm a ... | 1979 | 316320 |
| lesions of spontaneous canine viral enteritis. | spontaneous enteric disease characterized by hemorrhagic diarrhea and high mortality occurred in puppies from commercial kennels in three midwestern states. microscopic lesions resembling those of panleukopenia in cats were seen in the intestines. the predominant features were necrosis of crypt epithelium, collapse or dilation of crypt lumina and villous atrophy. viral particles morphologically resembling parvovirus were found in the feces by direct electron microscopy. the canine virus reacted ... | 1979 | 505892 |
| isolation and immunisation studies of a canine parco-like virus from dogs with haemorrhagic enteritis. | a newly recognised canine parvo like virus was isolated from faeces of dogs with haemorrhagic enteritis. cell cultures from several species were susceptible to it. virus infected cells could be demonstrated by staining with fluorescent antibody reagents (prepared against canine virus or feline panleucopenia virus) or by haemagglutination with pig or rhesus monkey red blood cells. inhibition of haemagglutination by specific antiserum prepared in specific-pathogen-free beagles provided a convenien ... | 1979 | 516347 |
| a case of partial cerebellar hypoplasia in a cat. | a case of spontaneous ataxia accompanied by partial cerebellar hypoplasia in a two month old siamese kitten is described. the cause of cerebellar hypoplasia is unknown but the feline panleucopenia virus is number one to be suspected. | 1978 | 662593 |
| feline panleukopenia. iii. development of lesions in the lymphoid tissues. | germfree and specific pathogen-free cats were inoculated with feline panleukopenia virus. cats were necropsied 2 to 6 days after inoculation and tissues from the thymus, lymph nodes and spleen taken for histological and immunofluorescence studies. necrosis of lymphoid cells in the thymic cortex began 3 days after inoculation and continued for 5 to 6 days after inoculation when the thymus was nearly depleted of lymphocytes. immunofluorescence studies showed the lesions to be caused by virus. ther ... | 1978 | 685085 |
| effect of feline panleukopenia virus infection on development of humoral and cellular immunity. | cats were infected with feline panleukopenia virus (fplv) at various ages pre- and post-parturition. all fetuses infected at 35 days of gestation from one queen and a single fetus infected at 45 days of gestation from a second queen had a significant delay in time of skin allograft rejection. older fetuses and newborn kittens infected with fplv did not show this delay in rejection time. adult cats infected with fplv demonstrated a significant decrease in lymphocyte responsiveness to two t cell m ... | 1976 | 782787 |
| experimental feline panleucopenia in the conventional cat. | coventional kittens, 12-27 weeks old, were inoculated with cell-cultured feline panleucopenia virus and killed sequentially between day 3 and day 24 after inoculation. all developed a non-fatal mild disease between days 2 and 9, characterized by lymphopenia, neutropenia, listlessness, depression and the development of neutralizing antibodies to the virus. small intestinal bacterial counts were reduced during the period of maximal clinical disease, presumably a result of decreased food intake. th ... | 1976 | 936427 |
| retinal dysplasia due to feline panleukopenia virus infection. | | 1975 | 1184424 |
| decline in maternal immunity and antibody response to vaccine in captive cheetah (acinonyx jubatus) cubs. | blood was collected from captive cheetah cubs (acinonyx jubatus) from the ages of 4 to 12 wk and monitored for the decline in maternally derived antibodies to feline panleukopenia, herpes and calici viruses. a steady decrease was seen in most of the cubs. antibody responses to inactivated and/or modified live virus (mlv) vaccine also were measured. the strongest responses were seen post vaccination with mlv vaccine only. | 1992 | 1312644 |
| characterization of the stage(s) in the virus replication cycle at which the host-cell specificity of the feline parvovirus subgroup is regulated in canine cells. | feline panleukopenia virus (fplv), mink enteritis virus (mev), and canine parvovirus (cpv) are classified as a host-range variants. they show different host-range specificity in vivo and host-cell specificity in vitro. for instance, fplv and mev cannot grow or can grow only inefficiently in canine cell lines such as mdck and the canine fibroma cell line a72. here we have studied the mechanism(s) by which the different cell tropism is mediated in vitro. when fplv or mev was inoculated to a72 cell ... | 1992 | 1322591 |
| canine and feline host ranges of canine parvovirus and feline panleukopenia virus: distinct host cell tropisms of each virus in vitro and in vivo. | canine parvovirus (cpv) emerged as an apparently new virus during the mid-1970s. the origin of cpv is unknown, but a variation from feline panleukopenia virus (fpv) or another closely related parvovirus is suspected. here we examine the in vitro and in vivo canine and feline host ranges of cpv and fpv. examination of three canine and six feline cell lines and mitogen-stimulated canine and feline peripheral blood lymphocytes revealed that cpv replicates in both canine and feline cells, whereas fp ... | 1992 | 1323703 |
| mutations adjacent to the dimple of the canine parvovirus capsid structure affect sialic acid binding. | the erythrocyte receptor on rhesus macaque erythrocytes used by canine parvovirus (cpv) for binding in hemagglutination (ha) was examined. erythrocyte membrane proteins were electrophoresed and blotted to nitrocellulose and probed with [125i]-labeled cpv capsids, showing seven virus-binding proteins. treatment of erythrocytes or isolated membranes with clostridium perfringens neuraminidase virtually abolished virus binding. binding was also affected by treatment with potassium periodate and inhi ... | 1992 | 1329321 |
| multiple amino acids in the capsid structure of canine parvovirus coordinately determine the canine host range and specific antigenic and hemagglutination properties. | canine parvovirus (cpv) and feline panleukopenia virus (fpv) are over 98% similar in dna sequence but have specific host range, antigenic, and hemagglutination (ha) properties which were located within the capsid protein gene. in vitro mutagenesis and recombination were used to prepare 16 different recombinant genomic clones, and viruses derived from those clones were analyzed for their in vitro host range, antigenic, and ha properties. the region of cpv from 59 to 91 map units determined the ab ... | 1992 | 1331498 |
| specific diagnosis of parvovirus enteritis in dogs and cats by in situ hybridization. | in a retrospective study, the fixed intestines of 10 dogs and 10 cats with intestinal lesions characteristic of parvovirus infection were assayed for the presence of parvovirus by in situ hybridization and immunohistochemistry. parvoviral nucleic acid was localized by in situ hybridization in intestinal tissue in all 10 dogs and in nine of the 10 cats, whereas antigen was detected only in seven of 10 canine and eight of 10 feline intestines by immunohistochemistry. we conclude that an aetiologic ... | 1992 | 1333495 |
| canine parvovirus empty capsids produced by expression in a baculovirus vector: use in analysis of viral properties and immunization of dogs. | the vp-2 genes of canine parvovirus (cpv) and a recombinant consisting of cpv and feline panleukopenia virus (fpv) sequences were cloned into baculovirus expression vectors, fused to the baculovirus polyhedrin promoter. recombinant baculoviruses were prepared and the properties of the parvovirus proteins expressed in insect cells examined. the proteins produced were the same size as the authentic cpv vp-2 protein, and were produced late after infection; the quantity of proteins recovered from th ... | 1992 | 1371541 |
| mapping specific functions in the capsid structure of canine parvovirus and feline panleukopenia virus using infectious plasmid clones. | dna sequences between 0 and 98.8 genome map units (m.u.) from canine parvovirus (cpv) and feline panleukopenia virus (fpv) were cloned into plasmid vectors to form infectious molecular clones. those plasmids were transfected into permissive cells and viruses recovered were shown to contain intact genomes, having regenerated the complete viral 5' ends up to 100 m.u. the viruses derived from the plasmids were compared to the original viruses, and shown to be indistinguishable in antigenic type, he ... | 1991 | 1647068 |
| antigenic and genomic comparisons of some feline parvovirus subspecies strains. | fourteen feline parvovirus (fpv) strains isolated from cats, mink and dogs were comparatively examined on their antigenic and genetic diversities by using monoclonal antibodies against feline panleukopenia virus (fplv) and restriction enzyme analysis of viral dna. mink enteritis virus (mev) strains recently isolated in the northeastern area of the people's republic of china were found to possess more similar antigenic and genetic properties to the antigenic variant virus of canine parvovirus (cp ... | 1991 | 1649516 |
| antibody response of captive cheetahs to modified-live feline virus vaccine. | the antibody response of cheetahs (acinonyx jubatus) to modified live virus vaccine against feline panleukopenia (fplv), herpes (fhv) and calici (fcv) viruses was assessed by means of an enzyme-linked immunosorbent assay (elisa). in the first year of study, 82 cheetahs were bled pre-vaccination. of these, antibody levels to fplv were found in 100% of the animals. only 54% were found to have antibodies to fhv and 99% had antibodies to fcv. one month after booster vaccination with the same vaccine ... | 1991 | 1661784 |
| proteins specified by swine transmissible gastroenteritis virus: identification of non-structural proteins by two-dimensional electrophoresis. | four virus-induced non-structural proteins with apparent molecular weights of 11-14 kilodaltons (kda) were identified by two-dimensional electrophoresis in cells infected by tgev. differences in the number of non-structural proteins were observed among virulent and attenuated tgev strains as well as with two antigenically related feline and canine coronaviruses. | 1991 | 1662051 |
| studies on preparation of inactivated vaccines from cell cultures of mink enteritis virus (mev) and their immunity. | in this paper, superhigh reproductive rate strains of mev with titre more than ha8192x or tcid50 log10(9.7) have been achieved both by cultivation in cell lines with different susceptibility to mev and by isolating and identifying in field by the author. the systematic tests proved that s18 and l12 strains of mev are the best strains for vaccine preparation. in this study, the best means for the tissue cultivation of mev and the most advanced technological process for the production and detectio ... | 1991 | 1666290 |
| establishment and characterization of canine parvovirus-specific murine cd4+ t cell clones and their use for the delineation of t cell epitopes. | canine parvovirus (cpv)-specific t cell clones were generated by culturing lymph node cells from cpv-immunized balb/c mice at limiting dilutions in the presence of cpv antigen and interleukin-2 (il-2). all isolated t cell clones exhibited the cell surface phenotype thy1+, cd4+, cd8- and proliferated specifically in response to cpv antigen. after stimulation with cpv antigen in culture the t cell clones produced il-2 and proliferated in the absence of exogenous il-2. naive mice to which cpv-speci ... | 1990 | 1693162 |
| [the fip-titer (feline infectious peritonitis)]. | | 1991 | 1848954 |
| [experiences with a new cat coryza-panleukopenia-rabies combined vaccine]. | the development of a new combined vaccine against cat flu, panleukopenia and rabies should lead to a simplification of the vaccination calendar in small animal practice. in order to judge the suitability of the new vaccine, its efficacy, local tolerability, and safety were evaluated. all vaccinated cats developed high antibody titres against herpes-, calici-, panleukopenia- and rabies virus that persisted well during the trial of 18 months. in comparison to other vaccines containing a smaller nu ... | 1990 | 1964252 |
| construction and nucleotide sequence analysis of an infectious dna clone of the autonomous parvovirus, mink enteritis virus. | we have cloned the replicative form (rf-) dna of mink enteritis virus (mev), constructed an infectious recombinant plasmid containing mev dna and determined the nucleotide sequence of the cloned mev dna. rf-dnas were detected and infectious virus was generated when the recombinant plasmid containing the entire mev genome was introduced into feline kidney cell cultures. the mev genome was 5094 nucleotides (nt) in length; the 3' end of the virion strand contained a 205 nt palindromic sequence and ... | 1991 | 2016597 |
| serological survey of the iriomote cat (felis iriomotensis) in japan. | the iriomote cat (felis iriomotensis) was first discovered on iriomote island in the yaeyama islands of japan in 1965. ten male and 11 female adult cats were captured during the 6 yr period from 1983 to 1988. these were examined for evidence of viral and mycoplasmal infections. neither mycoplasma sp. nor ureaplasma sp. were detected in swab samples of oropharyngeal and urogenital regions. a foamy virus was isolated from the oropharyngeal swab of a female cat examined in 1988. feline leukemia vir ... | 1990 | 2110982 |
| nucleotide sequence of feline panleukopenia virus: comparison with canine parvovirus identifies host-specific differences. | the nucleotide sequence of feline panleukopenia virus (fpv) strain 193 was determined and compared with the sequence of canine parvovirus (cpv) strain n and partial sequences of fpv strain carl and cpv strain b. base differences were identified at 115 positions in these 5.1 kb genomes and predicted amino acid differences occurred at 40 positions. the two overlapping capsid protein genes contained almost twice as many base differences as the single non-structural protein gene (49 compared to 26) ... | 1990 | 2174965 |
| antigenic relationships among autonomous parvoviruses. | the antigenic relatedness of minute virus of mice (mvm), kilham rat virus (kr), h-1 virus (h-1), haemorrhagic encephalopathy of rats virus (her), porcine parvovirus (ppv), canine parvovirus (cpv), feline panleukopenia virus (fpv), goose parvovirus (gpv) and bovine parvovirus (bpv) was studied by immunofluorescence microscopy (fa) and by serum neutralization (sn). an antigenically related group comprising mvm, kr, her, ppv, cpv and fpv was recognized by fa and most reactions within the group were ... | 1986 | 2432167 |
| [electron microscopy in the diagnosis of enteritis in cats]. | over a five-year period (1981-1985) 346 faecal and intestinal samples of cats affected with diarrhoea were studied by electron microscopy. this method revealed the presence of virus in 144 out of 346 (41.6 per cent) samples studied. 117 (81.3 per cent) of these samples contained parvoviruses which were identified by using a specific immune serum (immuno electron microscopy). in addition, rotaviruses (two samples), coronaviruses (thirteen samples), coronavirus-like (ten samples) and picornavirus- ... | 1989 | 2539659 |
| regulated expression of the feline panleukopenia virus p38 promoter on extrachromosomal fpv/ebv chimeric plasmids. | feline panleukopenia virus/epstein-barr virus (fpv/ebv) chimeric expression plasmids were constructed to study regulation of the structural protein gene of the parvovirus, fpv, in a homologous cell culture system. detection and quantitation of activity from the native fpv promoter, p38, was facilitated by fusing the escherichia coli lacz gene with the fpv structural protein gene. feline cell lines which stably maintained these plasmids extrachromosomally were established. constitutive beta-galac ... | 1989 | 2542586 |
| comparison of feline parvovirus subspecific strains using monoclonal antibodies against a feline panleukopenia virus. | four monoclonal antibodies (mab) against a feline panleukopenia virus (fplv) tu 1 strain, one of the host range variants of feline parvovirus (fpv), were produced and applied for antigenic analysis of fplv, canine parvovirus (cpv) and mink enteritis virus (mev). all mabs were considered to be directed at epitopes on the virus capsid surface because they neutralized the infectivity and inhibited the hemagglutination (ha) of the homologous virus as well as other fpv strains. they were of the mouse ... | 1989 | 2544758 |
| feline parvovirus propagates in cat bone marrow cultures and inhibits hematopoietic colony formation in vitro. | feline parvovirus (fpv) causes leukopenia in naturally infected cats. we investigated the mechanism of hematopoietic depression by this virus in feline bone marrow cultured in vitro. in suspension cultures we demonstrated fpv propagation and replication using dna molecular hybridization. viral rna and dna were observed by in situ hybridization in about 10% of marrow cells at day 3. granulocytes and their precursors were virtually absent from infected cultures after six days. infected cells showe ... | 1989 | 2546625 |
| inhibitory effects of ribavirin alone or combined with human alpha interferon on feline infectious peritonitis virus replication in vitro. | the antiviral activities of ribavirin (1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide; virazole), either alone or in combination with recombinant human leukocyte (alpha) interferon (rhuifn-alpha), were evaluated against feline infectious peritonitis virus (fipv) in feline kidney-cell cultures. the 50% inhibitory dose (id50) of ribavirin for uninfected, rapidly dividing cells was approximately 17 micrograms ml-1 whereas the id50 for fipv was 2.5 micrograms ml-1. the therapeutic index (ti) of ... | 1989 | 2549687 |
| porcine parvovirus: dna sequence and genome organization. | we have determined the nucleotide sequence of an almost full-length clone of porcine parvovirus (ppv). the sequence is 4973 nucleotides (nt) long. the 3' end of virion dna shows a y-shaped configuration homologous to rodent parvoviruses. the 5' end of virion dna shows a repetition of 127 nt at the carboxy terminus of the capsid proteins. the overall organization of the ppv genome is similar to those of other autonomous parvoviruses. there are two large open reading frames (orfs) that almost enti ... | 1989 | 2794971 |
| comparisons of feline panleukopenia virus, canine parvovirus, raccoon parvovirus, and mink enteritis virus and their pathogenicity for mink and ferrets. | parvoviruses from mink (mink enteritis virus [mev]), cats (feline panleukopenia virus [fpv]), raccoons (raccoon parvovirus [rpv]), and dogs (canine parvovirus [cpv]) were compared. restriction enzyme analysis of the viral replicative-form dna revealed no consistent differences between fpv and rpv isolates, but cpv and mev isolates could be distinguished readily from other virus types. feline panleukopenia virus, rpv, and mev, but not cpv, replicated to high titers in mink. however, on the first ... | 1987 | 2823648 |
| [the growth of attenuated strains of canine parvovirus, mink enteritis virus, feline panleukopenia virus, and rabies virus on various types of cell cultures]. | the growth characteristics were studied in the attenuated strains of canine parvovirus cpva-bn 80/82, mink enteritis virus meva-bn 63/82 and feline panleucopenia virus fpva-bn 110/83 on the stable feline kidney cell line fe, and in the attenuated canine distemper virus cdv-f-bn 10/83 on chicken embryo cell cultures (keb) and cultures of the stable cell line vero. when the fe cultures were infected with different parvoviruses in cell suspension at moi 2-4 tkid50 per cell, the first multiplication ... | 1987 | 2827364 |
| a solid-phase fluorescent immunoassay for detecting canine or mink enteritis parvoviruses in faecal samples. | mink enteritis virus (mev) and canine parvovirus (cpv) were detected in faecal samples from experimentally or naturally infected minks and dogs, respectively, using antibody-coated polyacrylamide beads (immunobeads, ib) as the solid phase for immunofluorescence (if) tests. the specificity and sensitivity of the immunobead assay (iba) were studied by comparing it with an enzyme-linked immunoassay (elisa), a haemagglutination (ha) test and an if test using tissue cultures. the iba was as sensitive ... | 1987 | 2830702 |
| antibody and cell mediated immune responses to an inactivated feline panleukopenia virus vaccine. | | 1987 | 2830741 |
| effect of diethylcarbamazine on serum antibodies to feline infectious peritonitis in cats. | in preceding studies by the author, use of the immunomodulator drug diethylcarbamazine resulted in the detection of antibodies to feline oncornavirus-associated cell membrane antigen in nine feline leukaemia virus infected cats that had previously given negative results to this antibody. in the present report, seven diethylcarbamazine-treated cats developed higher serum antibody titres to feline infectious peritonitis more frequently than did seven untreated controls. since feline infectious per ... | 1988 | 2833042 |
| feline interleukin 1 production induced by feline infectious peritonitis virus. | | 1988 | 2834596 |
| a titration method of feline infectious peritonitis virus using immunoperoxidase antibody. | | 1988 | 2834597 |
| feline panleucopenia--in vivo infectivity studies. | feline panleucopenia virus was separated into "full" and "empty" particles by banding in caesium chloride ultracentrifugation. field cats free of serum neutralising antibodies were separately infected with "full", "empty" and "mixed" particles of the virus. no clinical disease was produced. however, cats infected with "full" particles developed antibody more rapidly than cats infected with the other particles. | 1988 | 2836989 |
| characterization of biological and antigenic properties of raccoon dog and blue fox parvoviruses: a monoclonal antibody study. | parvovirus isolates from blue foxes and raccoon dogs were characterized by studying their haemagglutination properties, host range in vitro and antigenic structure. in all 3 characters, raccoon dog parvovirus resembled canine parvovirus (cpv), while blue fox parvovirus was similar to mink enteritis virus (mev). monoclonal antibodies (mabs) were prepared against both viruses. raccoon dog parvovirus, while resembling cpv, had a unique antigenic site which could be specified by mabs. the pattern of ... | 1988 | 2836994 |
| feline panleukopenia virus replicates in cells in which cellular dna synthesis is blocked. | the components of the cell cycle for a feline embryo cell line were defined. thymidine (6mm)-supplemented medium reversibly arrested cells 1 h into the s phase of the cell cycle and was used in a double blocking procedure to synchronize cells to the early s phase. the kinetics of feline panleukopenia virus replication in synchronized cells was studied by using (i) inclusion body formation, (ii) a plaque assay for cell-associated and cell-free virus under one-step growth conditions, (iii) an enzy ... | 1985 | 2982022 |
| parvovirus (feline panleucopaenia virus) plaque formation. | a plaque assay was developed for feline parvovirus (fpv; feline panleucopaenia virus) in a feline embryo (femb) cell line. higher numbers and larger diameter plaques were obtained with a) seeding rates of 0.7 x 10(5) and 1.5 x 10(5) cells cf. 3 x 10(5) and 6 x 10(5) cells/well of 35 mm diameter, b) synchronised cells infected at the g1-s interface cf. nonsynchronised cells and c) 5 to 6 days incubation post inoculation. the plaque assay was standardised by using serum deprivation for 24 hours to ... | 1985 | 2986580 |
| rapid enzyme-linked immunosorbent assay for detecting antibodies to canine parvovirus. | a rapid screening assay for determining antibodies to canine parvovirus in dog serum using monoclonal antibodies and enzyme-linked immunosorbent assay (elisa) technology was developed. the elisa could be read visually, and the results correlated well with serum neutralization (sn) and hemagglutination inhibition (hi) titers. sera with sn less than or equal to 1:4 or hi less than or equal to 1:10 had an 87.9% correlation with elisa and sera with sn greater than or equal to 1:64 or hi greater than ... | 1985 | 2990264 |
| cloning and sequence of dna encoding structural proteins of the autonomous parvovirus feline panleukopenia virus. | approximately 80% of the genome of feline panleukopenia virus was cloned into pbr322. this dna included the transcription unit for the major viral mrna species. the nucleotide sequence of the cloned portion of the genome was determined. comparison of the feline panleukopenia virus sequence with the sequences of the parvoviruses minute virus of mice and h-1 revealed considerable homology between the three viruses on both the nucleic acid and protein levels. based on this homology, a model for the ... | 1985 | 2991581 |
| evaluation of tri-combinant vaccine for feline herpesvirus, calicivirus and panleukopenia virus infections in japanese native cats. | tri-combinant vaccine consisting of attenuated feline herpesvirus (fhv) and feline calicivirus (fcv) and inactivated feline panleukopenia virus (fplv), were evaluated for safety and efficacy, using japanese native cats and the viral strains isolated in japan. thirty-eight 9- to 12-week-old kittens were inoculated intramuscularly and subcutaneously with the vaccine. consequently, no adverse reaction was found, and protective efficacy was confirmed by challenge tests with the virulent strains of e ... | 1985 | 2998830 |
| the structural proteins of the autonomous parvovirus feline panleukopenia virus. | approximately 80% of the genome of feline panleukopenia virus was cloned into the plasmid pbr322. the entire 3943 nucleotide sequence of the cloned portion of fpv was determined. this dna includes the gene which codes for the structural proteins of the virus. portions of this gene were expressed in e. coli as fusion proteins with bacterial proteins. some of the fusion proteins were capable of raising neutralizing antibodies in guinea pigs. through the use of deletion mapping, monoclonal antibodi ... | 1985 | 3000149 |
| serologic evaluation of vaccinated american river otters. | the oklahoma department of wildlife conservation acquired 20 american river otters (lutra canadensis) between 1984 and 1985 for reintroduction into oklahoma waterways. in 1985, 10 otters were evaluated for serum antibody titers after vaccination with canine distemper virus, canine adenovirus type 2, canine parvovirus (cpv), feline panleukopenia virus (fpv), feline rhinotracheitis virus (frv), and feline calicivirus. prevaccination serum-virus neutralization (svn) antibody to feline rhinotracheit ... | 1985 | 3001000 |
| latex agglutination test for detecting feline panleukopenia virus, canine parvovirus, and parvoviruses of fur animals. | a latex agglutination (la) test for the detection of parvoviruses of fur animals, cats, and dogs was developed, and its sensitivity and specificity were compared with those of hemagglutination (ha) and the enzyme-linked immunosorbent assay (elisa). tissue culture isolation was used to confirm the specificity results. fecal samples from various sources were tested, including specimens from raccoon dogs and mink which were experimentally infected with parvoviruses by oral exposure. la compared fav ... | 1986 | 3007568 |
| growth of feline panleukopenia virus and canine parvovirus in vitro. | | 1986 | 3020296 |
| detection of mink enteritis virus in mink feces, using enzyme-linked immunosorbent assay, hemagglutination, and electron microscopy. | twenty-five mink were inoculated with mink enteritis virus (mev). fecal specimens were collected daily and were simultaneously evaluated for mev antigen by use of a direct enzyme-linked immunosorbent assay (elisa), hemagglutination (ha), and electron microscopy. results of the evaluations indicated that mev was shed in the feces on postinoculation days 5 and 6. the virus was not detectable by elisa or ha after postinoculation day 6, although viruses were found in reduced numbers by use of electr ... | 1986 | 3021033 |
| biological and physical comparison of mink enteritis virus feline panleukopenia virus and canine parvovirus. | | 1986 | 3023731 |
| a nonstructural protein of feline panleukopenia virus: expression in escherichia coli and detection of multiple forms in infected cells. | sequences coding for the nonstructural protein ns1 of the autonomous parvovirus feline panleukopenia virus were expressed in escherichia coli as fusion proteins. the fusion proteins were specifically bound by antisera from canine parvovirus-infected dogs. antisera against one of the fusion proteins bound to several proteins found only in feline panleukopenia virus-infected feline cells. | 1987 | 3027392 |
| comparison of porcine parvovirus to other parvoviruses by restriction site mapping and hybridization analysis of southern blots. | the genomic relationship between porcine parvovirus (ppv) and several other autonomous parvoviruses was examined by restriction site and hybridization analysis. restriction site maps of the ppv genome were prepared by digesting the double-stranded replicative form of the viral dna with each of eight restriction enzymes. subsequent comparison of such maps with those previously reported for ppv, canine parvovirus (cpv), feline panleukopenia virus (fpv), minute virus of mice (mvm), h-1 virus (h-1) ... | 1987 | 3029312 |
| preliminary development of a live attenuated canine parvovirus vaccine from an isolate of british origin. | canine parvovirus isolated from a case of haemorrhagic enteritis in a breeding kennel in england was passaged and cloned in cultured feline and canine cells. no significant evidence of pathogenicity was found during six serial passages of the modified virus back through young dogs. the attenuated virus was excreted by inoculated animals and spread rapidly to uninoculated animals held in contact. when high titre attenuated virus was given to the six-week-old offspring of a seropositive dam a prom ... | 1987 | 3035779 |
| parvovirus-induced regression of canine transmissible venereal sarcoma. | in 1981, during the worldwide canine parvovirus (pv) epizootic, canine transmissible venereal sarcomas growing in beagles in a colony regressed earlier than expected after the dogs became infected with pv. subsequent studies revealed that modified-live pv vaccine (feline panleukopenia virus) was capable of preventing tumor transplantation when the vaccine was inoculated simultaneously with the tumor in a site distant from the implantation site. however, the pv vaccine had no effect if it was ino ... | 1987 | 3035973 |
| the propagation of feline panleukopenia virus in micro-carrier cell culture and use of the inactivated virus in the protection of mink against viral enteritis. | using microcarrier cell culture for the production of virus antigen, a formalin-inactivated feline panleukopenia virus vaccine was evaluated for protection of mink against specific mink enteritis virus infection. the vaccine showed a good immunogenic effect in mink when used either alone or in combination with clostridium botulinum type c-toxoid and/or pseudomonas aeruginosa vaccine. a single vaccination induced persistent immune responses for periods of at least 1 year, as evaluated by elisa an ... | 1987 | 3037766 |
| virus and virus-like particles in the faeces of cats with and without diarrhoea. | negative staining electron microscopy was used to identify viruses in 166 normal and 62 diarrhoeal faecal samples from 208 cats admitted to an animal shelter during a 16-month period (march 1984 to june 1985). on the basis of size and shape 7 distinct viral types were detected: 24 nm parvovirus-like particles, 30 nm astrovirus, 30 nm picornavirus-like particles, reovirus, rotavirus, coronavirus and a 75 nm "togavirus-like" particle. the incidence of these particles in the 208 cats was 11%, 7%, 6 ... | 1987 | 3039960 |
| canine host range and a specific epitope map along with variant sequences in the capsid protein gene of canine parvovirus and related feline, mink, and raccoon parvoviruses. | canine parvovirus (cpv) is a recently recognized pathogen of dogs that is similar to the long-recognized feline, mink, and raccoon parvoviruses. relationships between the viruses determined from dna sequences of the capsid protein genes of 10 virus isolates showed the cpv isolates to be closely related to the other viruses, although comprising a distinct group. no immediate ancestor of cpv was observed amongst the mink, cat, or raccoon viruses examined. three different directly repeated sequence ... | 1988 | 3176341 |
| canine parvovirus: strain difference in haemagglutination activity and antigenicity. | canine parvovirus (cpv) strains were compared for haemagglutination (ha) activity and antigenicity and were divided into two types by ha activity. strains cp49 and 29-f showed temperature-dependent ha, like feline panleukopenia virus (fplv) and mink enteritis virus (mev), whereas strains sp-80 and y-1 showed temperature-independent ha with erythrocytes from eight species of animals. the results of a cross ha inhibition test using immunized rat sera suggested that of the two types of cpv those sh ... | 1988 | 3339330 |
| clinical, hematological, and pathological findings in specific pathogen-free cats experimentally infected with feline panleukopenia virus. | | 1987 | 3573491 |
| complete nucleotide sequence and genome organization of bovine parvovirus. | we determined the complete nucleotide sequence of bovine parvovirus (bpv), an autonomous parvovirus. the sequence is 5,491 nucleotides long. the terminal regions contain nonidentical imperfect palindromic sequences of 150 and 121 nucleotides. in the plus strand, there are three large open reading frames (left orf, mid orf, and right orf) with coding capacities of 729, 255, and 685 amino acids, respectively. as with all parvoviruses studied to date, the left orf of bpv codes for the nonstructural ... | 1986 | 3783814 |
| some properties of feline panleukopenia virus. | | 1973 | 4128925 |
| feline viruses. iv. isolation and characterization of feline panleukopenia virus in tissue culture and comparison of cytopathogenicity with feline picornavirus, herpesvirus, and reovirus. | | 1970 | 4191787 |
| enzyme histochemistry of the small intestine in germfree and specific-pathogen-free cats inoculated with feline infectious enteritis (feline panleukopenia) virus. | | 1970 | 4249951 |
| enzyme histochemistry of lymphoid tissues in germfree cats inoculated with feline infectious enteritis (feline panleukopenia) virus. | | 1970 | 4249952 |
| a new vaccine strain of feline panleukopenia virus grown in ferret cell culture. | | 1974 | 4491924 |
| a study on in vitro isolation of feline panleukopaenia virus. | | 1973 | 4520222 |
| relationship of mink virus enteritis virus and feline panleukopenia virus: rapid onset of mink virus enteritis virus protection after feline panleukopenia virus infection. | | 1972 | 4673226 |
| absence of an immune response after oral administration of attenuated feline panleukopenia virus. | cats were orally vaccinated with attenuated feline panleukopenia virus to compare this route with parenteral immunization. cats receiving vaccine virus by mouth did not produce a systemic or local antibody response to the virus. intranasal and subcutaneous vaccination produced high levels of neutralizing antibodies and provided protection from challenge with virulent virus. the results suggest that virus does not initially infect the tissue of the oral pharynx or gastrointestinal tract as previo ... | 1973 | 4762109 |
| immune carrier state of feline panleukopenia virus-infected cats. | | 1971 | 4928338 |
| studies on cell culture adapted feline panleukopenia virus. virus neutralization & antigenic extinction. | | 1966 | 4954628 |
| identity of feline ataxia virus with feline panleucopenia virus. | | 1967 | 4962202 |
| congenital infections of cats and ferrets by feline panleukopenia virus manifested by cerebellar hypoplasia. | | 1967 | 4965699 |
| cerebellar ataxia and its congenital transmission in cats by feline panleukopenia virus. | | 1971 | 5103504 |
| comments on cerebellar ataxia and its congenital transmission in cats by feline panleukopenia virus. | | 1971 | 5103505 |