| effect of environmental ph on adenovirus-associated virus. | the influence of environmental ph on aav was studied in infectious virus titrations, induction of cf antigens production of infectious virus, induction of immunofluorescent stainable antigen, and aggregation of the viral particles. the ph of the medium was found to influence the titer of virus stocks in that less virus was registered at acid ph's, giving differences of up to 105 tcid50 in hek and hep-2 cells. less infectious virus was produced in kb cells, and decreased amounts of cf antigen app ... | 1975 | 1792 |
| experiments on the role of virus infections in the pathogenesis of bronchial asthma. the role of innate or acquired insufficiency or ergotropic adaptation in the mechanism of genesis of bronchial asthma. | the wide mosaic of congruent clinical and experimental observations led to the postulation that the cause of the pharmacological abnormality of the asthmatic patient, i.e. the immensely increased reactivity of the bronchial smooth muscles, is to be sought in an insufficiency of the beta-adrenergic receptor system. it is to be assumed that the so-called asthma diatheses is based inter alia on a genetically determined defect of the adenyl cyclase system. the role of previous infections of the resp ... | 1976 | 4969 |
| interferon-producing capacity of human tonsil cells and properties of interferon produced by these cells. | tonsils excised from human beings for chronic tonsillitis have been shown to be an accessible and sufficiently rich source of human lymphocytes. tonsil cells produced interferon as intensively as blood leukocytes and the properties of this interferon were similar to those of leukocyte interferon. the optimal conditions for interferon production by tonsil cells were established. | 1976 | 5865 |
| interferon pretreatment primes interferon production by human adenovirus in chick embryo cells. | pretreatment of chick embryo cells (cec) with homologous interferon enhanced the subsequent interferon production induced by human adenovirus. this priming effect of interferon pretreatment was also demonstrable when trypsin-treated virus was used for the induction of interferon. | 1976 | 5873 |
| improved methods for detecting enteric viruses in oysters. | new and improved methods for concentrating enteroviruses, reoviruses, and adenoviruses from oysters have been developed and evaluated. viruses are efficiently adsorbed to homogenized oyster meat by adjusting the homogenate to ph 5.0 and a conductivity of less than or equal to 2,000 mg of nacl per liter. after low-speed centrifugation, the virus-free supernatant is discarded and the viruses are eluted from the sedimented oyster solids with ph 7.5 glycine-nacl having a conductivity of 8,000 mg of ... | 1978 | 29555 |
| viruses and bacteria associated with acute respiratory illnesses in young children in general practice. | the results obtained and the laboratory methods used for the isolation of viruses and bacteria from malaysian children with acute respiratory illnesses seen in a private clinic are described. of the 65 children studied virus isolations were obtained from 26 children, bacteria from 10 and both virus and bacteria from another 5. the agents isolated were influenza viruses, parainfluenza viruses, adenoviruses, bordetella pertussis, streptococcus pneumoniae, haemophilus influenzae and staphylococcus ... | 1978 | 30173 |
| [virological diagnosis of epidemic keratoconjunctivitis (author's transl)]. | among 180 patients with proved adenovirus infection of the eye, 144 infections with adenovirus 8 (ad 8) were found. 11 or 7 patients were infected with ad 19 or ad 4 respectively; further 18 cases were associated with 6 other serotypes. the main symptoms of epidemic keratoconjunctivitis (ekc) (pronounced inflammatory swelling of the plica and caruncula, nummular corneal infiltations) are not confined to ad 8 infections. for the virological diagnosis, a combination of virus isolation and serology ... | 1979 | 44795 |
| the susceptibility of vero cell cultures for human adenoviruses. | human adenoviruses 1 to 28 were shown to produce a cytopathic effect in vero cell cultures. viruses of subgroups iii and iv (ad 1, 2, 5, 6, 12, and 18) were readily passaged in vero cell cultures and were produced in high amounts. this was also found for ad 11, 16, and 21, while ad 3, 4, and 7 showed a lower degree of multiplication and ad 14 could not be passed serially. for ad 8, 26, 27, 20, 25, and 28, a multiplication in vero cells could not be proved, while the remaining serotypes of subgro ... | 1978 | 45601 |
| triphenylmethane dyes as inhibitors of reverse transcriptase, ribonucleic acid polymerase, and protein synthesis. structure-activity relationships. | | 1975 | 45883 |
| epidemic viral enteritis in a long-stay children's ward. | two outbreaks of acute gastroenteritis occurred in 1974 in a long-stay children's ward. electron microscopy demonstrated rotaviruses in faeces from the affected children in the first outbreak, and adenoviruses in faeces from affected children and a nurse in the second outbreak. the illness in both outbreaks was very mild; but the diarrhoea associated with rotavirus infection usually lasted 5-8 days (in one patient it lasted for 28 days) and sometimes started with vomiting; whereas the adenovirus ... | 1975 | 46358 |
| importance of a new virus in acute sporadic enteritis in children. | in a year-long survey of children admitted with acute enteritis to hospital in melbourne, australia, an aetiological agent was found in approximately 75% of patients. during most months of the year a newly described virus belonging to the family reoviridae was detected by electron microscopy of faecal extracts from more than 50% of patients. recovery of this virus reached a peak (73%) during the winter. all age-group up to five years of age were susceptible to infection, which was occasionally f ... | 1975 | 46387 |
| fine structure of adenovirus type 5. i. virus capsid. | | 1975 | 48307 |
| the specificity of cellular immune reactions to three dna virus induced tumours, as measured by the macrophage migration inhibition test. | | 1975 | 48461 |
| letter: virus-associated gastroenteritis in children. | | 1975 | 51388 |
| antigenic determinants of adenovirus capsids. i. measurement of antibody cross-reactivity. | evidence is presented that the type-specific antibody to the adenovirus hexon is not simply the antibody with the highest activity for cross-reactive determinants, but is a distinct, minority population that recognizes seperate determinants. to quantify it, we have developed an inhibition method with radio-immunoprecipitation (rip) as a sensitive assay for the type-specific antibody that remains after all the excess of cross-reactive antibody has been blocked by heterologous antigen. during the ... | 1976 | 54385 |
| antigenic determinants of adenovirus capsids. ii. homogeneity of hexons, and accessibility of their determinants, in the virion. | we have tested the two principal theories which explain the previous finding that small amounts of type-specific antibody to the adenovirus hexon can neutralize infectivity, whereas even large amounts of cross-reactive antibody do not. a) it has been suggested that the type-specific determinants are especially prominent in the virion. we have therefore measured the capacity of whole virus to bind appropriate antibodies, using a sensitive radioimmunoprecipitation (rip) system. in fact, virions bo ... | 1976 | 54389 |
| terminal dilution purification of adenovirus prototypes, and the antigenic relationship between types 4, 16 and 14. | two terminal dilution purifications in hek cells were performed with adenovirus prototypes of types 1 to 7, 12, 16, 19 and 9-15, and one terminal dilution with a freshly isolated type 8 strain. the antisera prepared against viruses after terminal dilution neutralized the original and the purified virus to the same extent, indicating the antigenic purity of the respective prototypes. cross-reactions in neutralization with other types within the subgroup were also identical. only the prototype of ... | 1975 | 55114 |
| [level of viral antibodies in normal and specific swine and bovine gamma globulin preparations]. | studied were 15 series of normal bovine gamma-globulin, 5 series of normal swine gamma-globulin, 7 series of aujeszky gamma-globulin, 6 series of specific gamma-globulin against edema disease of pigs, 4 series of specific gamma-globulin against paratyphus, 5 series of mixoglobulin-70, and one series of swine poly-globulin. all series of gamma-globulin preparations were studied for the presence of antibodies against mixovirus parainfluenza-3 through the hemagglutinationinhibition reaction, antibo ... | 1975 | 58467 |
| [presence of antigen sv40/t in the nuclear and cytoplasmic fraction of sv40- and para-transformed cells]. | | 1975 | 58585 |
| laboratory procedures in adenoviruses. iii. sensitivity and specificity of serological tests (author's transl)]. | 84 paired sera from patients with adenoviral infections were tested in neutralization and hemagglutination-inhibition (hi) against the homologous as well as against heterologous virus types of the respective subgroup. only titer rises are considered as positive reactions. sera of patients being infected with adenoviruses of subgroup i viruses (52 pairs, types 7, 3, 4, 14) exhibit high rates of positive reactions in the group-specific complementfixation (cf) and in homologous neutralization, lowe ... | 1976 | 59498 |
| simian virus to (sv40) tumor-specific proteins in nucleus and plasma membrane of hela cells infected by adenovirus 2-sv40 hybrid virus ad2+nd2. | hela cells infected with the nondefective adenovirus 2-sv40 hybrid virus (ad2+nd2) have previously been shown to synthesize two sv40-specific proteins with molecular weights of 56,000 (56 k protein) and 42,000 (42 k protein). the present study demonstrates that these proteins are immunoprecipitable with serum from hamsters bearing sv40 tumors. by peptide analysis, it is shown that the 56 k and 42 k proteins share common amino acid sequences. both proteins are metabolically stable in nuclei and p ... | 1976 | 59927 |
| proceedings: studies on the excision process of sv40-dna during infection with adeno-sv40-hybrid ad.2++ hey. | | 1976 | 60967 |
| a study of possible biohazards in the fluorescent antibody test using adenovirus, coxsackievirus, herpesvirus, and respiratory syncytial virus as antigens. | infectious adenovirus type 5 and coxsackievirus type b5, both nonlipid-containing viruses, were isolated from cells fixed in acetone at 22 degrees c for 15 min, from acetone used for fixation, from the solution used for washing slides during the fluorescent antibody procedure, and after complete processing of antigen preparations with serial twofold dilutions of human antisera and fluorescein-labeled goat anti-human immunoglobulin g. lipid-containing herpes simplex virus type 1 and respiratory s ... | 1976 | 61971 |
| adenovirus type 7; 1971-74. | the spread of adenovirus type 7 in england and wales between 1971 and 1974 and the clinical features of infections with this virus were investigated in a retrospective study of virological reports and patients' clinical records. an epidemic in 1972-74 apparently stared in the north-east and spread to the south-west. between march 1973 and the end of october 1974 the virus was recovered in 59 of 74 specimens from 42 patients. the mean age of the patients was 9 years, which suggests that a large p ... | 1976 | 62264 |
| [artificial heterogenization of tumors]. | | 1976 | 63180 |
| effect of ethidium bromide on transplanted virus-induced tumor cells. | ethidium bromide (2,3-diamino-5-ethyl-6-phenylphenanthridinium bromide) significantly inhibited the rna-dependent dna polymerase of types a and c particles isolated from transplanted adenovirus 12-induced tumors of cba mice. it was also cytotoxic for an established in vitro line of adenovirus 12-induced tumor cells of cba mice and caused cell death, inhibition of [3h]thymidine uptake, and a significant reduction of cells in metaphase. ethidium bromide significantly inhibited the in vivo growth o ... | 1976 | 63562 |
| aplastic anaemia, bone-marrow transplantation, and polyoma and other virus infections. | | 1977 | 66488 |
| enhancement of ige-mediated histamine release from human basophils by viruses: role of interferon. | human leukocytes maintained in culture are induced to release histamine when exposed to ragweed antigen e or anti-ige. leukocyte cultures incubated with virus (i.e. hsv-1, influenza a, and adeno-1) but not exposed to ragweed antigen e or anti-ige fail to release histamine. if, however, leukocyte cultures are first exposed to virus and then to ragweed antigen e or anti-ige, significant enhancement of histamine release occurs. both infectious and inactivated virus enhance histamine release and the ... | 1977 | 67173 |
| new human adenovirus (candidate adenovirus type 35) causing fatal disseminated infection in a renal transplant recipient. | an antigenically distinct adenovirus is described which was isolated in march 1973 from the lungs and kidney of a 61-year-old woman who died of diffuse interstitial adenovirus pneumonia 55 days after receiving a cadaveric renal allograft. complement fixation, hemagglutination inhibition, and serum neutralization tests on sequential serum specimens from the patient confirmed that the adenovirus infection occurred in coincidence with her clinical illness and failed to document concomitant infectio ... | 1977 | 71305 |
| [structural components of adenvoiruses and other dna-genome viruses]. | | 1978 | 78433 |
| [morphological virus diagnosis--electron microscopy study of animal viruses with negative contrast procedure]. | reported in this paper are results obtained in morphological virus diagnosis by using the negative contrast technique on the basis of electron microscopy. the availability of high-efficiency electron microscopy as well as of perfectly improved techniques of preparation, knowledge of the latest virus model concepts, and indivudual skills in diagnosis are essential conditions for the above approach. parvoviridae, picornaviridae, and togaviridae are identifiable only in high particle concentrations ... | 1978 | 83124 |
| [use of the precipitation reaction for studying viral antibodies in blood sera]. | | 1979 | 89261 |
| inhibition of adenovirus replication in vitro by trifluridine. | at present, there is no effective chemotherapeutic agent available for the treatment of adenoviral keratoconjunctivitis. recent evidence suggests that trifluridine (3ft) may effectively inhibit the replication of some adenovirus serotypes known to cause keratoconjunctivitis. the ability of 3ft to inhibit two reference strains of adenoviruses, type 8 and type 19, was examined using cell cultures. two second-passage isolates of adenoviruses, identified as serotype 13, were also tested. compared wi ... | 1978 | 99133 |
| serologic distribution of antibodies against adenoviruses in sheep of large-scale farms. | the common soluble antigen of the first subgroup of bovine adenoviruses was used for assaying 793 sheep sera by the agar gel diffusion test. of the 50 farms included in the study 43 were found infected. the ratio of reacting samples was 73.7% of the sera obtained from infected farms. virus neutralization tests revealed that a considerable number of sera reacted specifically with all types of ovine adenoviruses, even with serotypes which had never been isolated in hungary. the results yielded by ... | 1978 | 99987 |
| amanitins in virus research. | | 1978 | 100081 |
| isolation of animal viruses from farm livestock waste, soil and water. | ten porcine enteroviruses, 2 porcine adenoviruses and 1 coronavirus were isolated directly from 32 samples of slurry collected from a pig fattening house. concentration of the same samples by adsorption with the polyelectrolyte pe-60 yielded 24 porcine enteroviruses and 3 porcine adenoviruses. a porcine enterovirus was isolated, following pe-60 concentration, from 1 to 6 slurry samples from a sow farrowing house. no virus was isolated from 12 samples of slurry from dairy cows nor from 6 slurry s ... | 1978 | 100551 |
| late transcription and simultaneous replication of simian adenovirus 7 dna as revealed by spreading lytically infected cell cultures. | miller's technique of spreading dna was applied to monkey cells productively infected with simian adenovirus 7. this permitted the visualization of cellular dna transcription, both nucleolar and non-nucleolar, and of late transcription and replication of virus. virus double-stranded dna, thin fibres with very few nucleosome-like particles, were observed carrying either transcription or replication complexes. in addition, both rnp transcripts and replication forks were found on some virus duplex ... | 1979 | 107271 |
| [physicochemical properties of the dna of simian adenovirus type 38]. | the sedimentation constant, specific viscosity, and the length of dna molecule of simian adenovirus type 38 were measured and the molecular weight was estimated. the melting temperature and buoyant densities of this virus dna in cesium chloride and cesium sulphate density gradients were determined, and the content of gc-pairs was calculated. | 1979 | 107653 |
| [hemagglutination by simian adenovirus 7]. | simian adenovirus 7, either complete virus or its capsid subunits, agglutinates rat (sprague-dowley) red blood cells in the presence of heterotypical antiserum. haemagglutination takes place at 4 degrees c and room temperature. the antigen could not be eluted and its haemagglutinin properties are heat-stable. the reaction is specific. it is inhibited by homologous antiserum only. this property and its characteristics permit a camparison of this strongly oncogenic adenovirus to the human adenovir ... | 1979 | 108027 |
| increased integration of viral genome following chemical and viral treatment of hamster embryo cells. | treatment of hamster embryo cells with diverse classes of chemical carcinogens enhances transformation by a carcinogenic simian adenovirus, sa7. virus transformed foci selected from plates pretreated with 3-methyl-cholanthrene (mca), methyl methanesulfonate (mms) or 7,12-dimethylbenz[a]anthracene (dmba) and established as cell lines in culture, contained equivalent amounts of sa7 viral genome. however, hamster embryo cultures treated with mms or nickel sulfate had increased amounts of sa7 dna in ... | 1979 | 111805 |
| biological activity of the intact and cleaved dna of the simian adenovirus 7. | only the deproteinized dna preparations of the simian adenovirus of the type 7 (sa 7) exhibited transforming and tumorigenic activity. the complex of the sa7 dna with terminal protein (tp) did not exhibit either transforming or tumorigenic activity in cell cultures. in contrast to the transforming potential the infectious titers of the dna - tp complex for the monkey kidney cells were 30-50 times higher than those of pure dna. cleavage of the sa7 dna by specific endonucleases enhanced the tumori ... | 1979 | 114980 |
| [transforming activity and the oncogenicity of simian adenovirus sa7 dna]. | the transforming and oncogenous activity of uncleaved dna of simian adenovirus sa7 (adsa7) and the products of its restriction by endonucleases r. bam hi and r. sali was studied. it was shown that uncleaved virus dna transformed the rat kidney cells and rat embryo fibroblasts and induced tumors in newborn hamsters. adsa7 dna, hydrolysed by r. bam hi, posessed the transforming activity. the mixture of dna fragments, obtained after hydrolysis by r. sali was oncogenous in hamsters. | 1979 | 117850 |
| in vitro studies on target cells of oncogenic adenoviruses in hamster brain. ii. in vitro transformation of brain cells of hamsters at various ages by human adenovirus type 12. | in vitro transformations of brain cells of hamsters of various ages were examined after the administration of human adenovirus type 12 (ad 12) to determine the type and origin of the target cell. hamster brain cells at all examined ages were transformed by ad12. although the virus was not isolated, virus specific tumor antigen was demonstrated in the transformed cells. the histological features of tumors that developed by transplantation of transformed cells closely resembled ad12-induced brain ... | 1975 | 132084 |
| in vitro studies on target cells of oncogenic adenoviruses in hamster brain. iii. in vitro transformation of brain cells of hamsters at various ages by bovine adenovirus type 3. | in vitro transformation of brain cells of hamsters at various ages was examined after the addition of bovine adenovirus type 3 to determine the type and origin of the target cells. cellular transformations occurred only in cultures of fetus and newborn animals and at low incidences. nine cell lines were obtained. virus specific tumor antigens were demonstrated in the transformed cells. the present investigation suggested that bovine adenovirus type 3 might transform mesenchymal cells (me cell) a ... | 1975 | 132085 |
| mechanism of induction of cellular immunity to virus infections: experiments with adenoviruses. | | 1977 | 147642 |
| [evaluation of immunization against influenza with adenovirus containing strains a/port chalmers and a/swine (author's transl)]. | | 1978 | 153798 |
| [viral respiratory infections]. | | 1975 | 162793 |
| viral respiratory infections of horses: structure and function of lungs in relation to viral infection. | since the advent of cell culture techniques, numerous viruses have been shown to be related to respiratory diseases in horses. although the viruses differ in many ways, they cause disease with some common characteristics. this report is a summary of some of the available material from written sources and from personal observations. it is intended to help explain some of the changes observed in viral-induced respiratory disease. | 1975 | 162902 |
| role of respiratory viruses in childhood mortality. | respiratory viruses have been identified at necropsy in the lungs of 13 out of 24 children who died with observed acute respiratory illness. the histological appearances of the lungs supported the association between virus and death in each of these 13 children and suggested an unidentified virus aetiology in a further five cases. histological appearances compatible with bacterial infection were found in the lungs of only two of the 24 children. similar virus and histological findings have been ... | 1975 | 163114 |
| infectious bovine keratoconjunctivitis i. experimental production. | one or both eyes of 20 calves were inoculated one or more time with variou(s combinations of microorganism (live oor killed moraxella bovis, infectious bovine rhinotracheitis virus, bovine adenovirus, bovine parainfluenza-3 virus and mycoplasma bovoculi) by conjunctival instillation or direct inoculation of the conjunctivea or cornea. the eyes of all the calves received natural or artificial ultraviolet irradiation. neither the adenovirus nor parainfluenza-3 virus became established in the eye o ... | 1975 | 163126 |
| potentiation of an adenovirus-associated virus by herpes simplex virus type-2-transformed cells. | the herpes simplex virus type-2 (hsv-2)-transformed cell line 333-8-9 was inoculated with adeno-virus-associated virus type 3 (aav-3) and examined by immunofluorescent (fa) techniques for evidence of aav-3 antigen synthesis. antisera prepared against the three sodium dodecyl sulfate-dissociated structural polypeptides (vp-1, vp-2, and vp-3) of aav-3 and against the whole aav-3 virion were used as probes to search for aav-3 fa-stainable antigens synthesized by these cells. the 333-8-9 cells inocu ... | 1975 | 163319 |
| stimulation of adenovirus replication in simian cells in the absence of a helper virus by pretreatment of the cells with iododeoxyuridine. | pretreatment of african green monkey kidney cells with 50 mu g of 5'-iododeoxyruidine (iudr) per ml can modify their susceptibility to the replication of human adenovirus type 7 in the absence of simian virus 40 (sv40) although this enhancement of adenovirus replication is not as efficient as that of the helper sv40 virus. since the number of infectious centers remains unchanged after iudr pretreatment whereas the burst size of virus from each infected cell increases, the iudr appears to allow e ... | 1975 | 163353 |
| [letter: virus infections in malignant tracheobronchitis in infants]. | | 1975 | 163464 |
| equine infectious respiratory disease. | during the past 20 years the equine population of great britain and ireland has increased with the result that the practising veterinary surgeon is more frequently called upon to advise on equine problems. a significant portion of this advice is concerned with the examination of horses showing signs of this advice is concerned with the examination of horses showing signs of respiratory disease. numerous pathogens, which include viruses, bacteria, parasites and moulds invade the respiratory tract ... | 1975 | 163516 |
| studies on the regulation of deoxypyrimidine kinases in normal, sv40-transformed and sv40- and adenovirus-infected mouse cells in culture. | | 1975 | 163528 |
| [mixed viral infections in premature newborn infants]. | | 1975 | 163548 |
| comparison of the immunogenicity of hamster cells transformed by adenovirus and herpes simplex virus. | hamsters vaccinated with adenovirus-transformed cells, modified by acetoacetylation or concanavalin a treatment, or with small numbers of living cells were partly or completely protected against challenge with 3 times 10-6 living cells. treatment of vaccine cells with iodoacetate, mitomycin c, neuraminidase plus mitomycin c did not produce efficient vaccines. herpes simplex virus-transformed cells treated by any of these procedures did not prevent, and frequently even enhanced, the growth of the ... | 1975 | 163694 |
| adenovirus-transformed cells restrict herpes simplex virus replication. | a cell line that normally supports the replication of herpes simplex virus types 1 and 2 became resistant to these viruses after transformation by simian adenovirus 7. kinetic studies of the mechanism of resistance demonstrated that both herpesviruses were able to attach to the transformed cells and express some early genomic functions, as demonstrated by the presence of low levels of viral thymidine kinase. however, isopycnic centrifugation studies of the abortive system failed to detect viral ... | 1975 | 163798 |
| spleen cell-mediated cytotoxicity of hamster cells transformed by herpes simplex virus: evidence for virus-specific membrane antigen. | the nature of the host's immune response to isografts of hamster embryo fibroblasts (hef) transformed by herpes simplex virus type 1 (hsv-1) was investigated by the microcytotoxicity assay. it was found that spleen cells from tumor-bearing hamsters killed homologous tumor cells but not hef transformed by cytomegalovirus or para-(defective sv40)-adenovirus 7 (para-7). cytotoxicity was lost as the tumor increased in size. spleen cells from animals bearing isografts of hsv type 2 (hsv-2) transforme ... | 1975 | 163859 |
| [epidemic keratoconjunctivitis: a report on a clinical epidemic (author's transl)]. | after description of the clinical and serological features of an epidemic keratoconjunctivitis caused by adeno-virus (type 8) the author compares results of 4 methods of treatment. the schedule consisted of "okuzell-coldan" eye drops as placebo, eye drops of corticosteroid content, intramuscular inoculation with interferonogen and a combined treatment with 0.3 percent "neutralrot" eye drops and radiation with daylight lamp hpr 125 w produced by philips co. ltd. the transition from the conjunctiv ... | 1975 | 163937 |
| the use of vaccines in respiratory virus infections. | | 1975 | 163955 |
| [clinical aspects of rs virus infections based on studies of infants at a pediatric department]. | | 1975 | 164000 |
| assembly of viruses. | | 1975 | 164048 |
| structural and functional alterations in cultured cells infected with cytocidal viruses. | | 1975 | 164054 |
| viral infection and psychiatric disorders. | a psychiatric population of 94 inpatients and 12 outpatients was investigated on referral to a psychiatric unit in a general hospital for serum antibody titres to several viruses by a complement fixation technique. of the total population studied, only eight were considered to have antibody titres of possible significance. this result would appear to indicate that viral infection does not play a major part in the causation or precipitation of psychiatric disorders. | 1975 | 164099 |
| growth of sv 40, adeno 7 and sv 40-adeno 7 viruses in monkey and human cells at 29 degrees and 37 degrees c. | adeno 7 virus replicated well in human diploid (lep) cells but only to a low degree in green monkey kidney (gmk) cells at 37 degrees c; it did not replicate in either system at 29 degrees c. at 37 degrees c sv 40 virus replicated well in gmk cells but only moderately in lep cells; at 29 degrees c it did not replicate in either system. sv 40-adeno 7 hybrid grew in both gmk cells and lep cells at 37 degrees c. at 29 degrees c this virus replicated in gmk cells but not in lep cells. while the forma ... | 1975 | 164162 |
| mechanism of induction of cell-mediated immunity to virus infections: in vitro inhibition of intracellular multiplication of mouse adenovirus by immune spleen cells. | mice were protected from lethal infection with mouse adenovirus (m-ad) by adoptive transfer of immune spleen cells (isc) that were prepared from mice immunized with m-ad and not protected by sonicated isc. however, a similar extent of protection was also observed by passive immunization with anti-m-ad serum. in contrast, by in vitro experiments isc were shown to be able to interrupt intracellular multiplication of m-ad, whereas sonicated isc, unimmunized mouse spleen cells, or anti-m-ad serum we ... | 1975 | 164414 |
| respiratory viral infection in childhood. a survey in general practice, roehampton 1967-1972. | the role of viruses and m. pneumoniae in episodes of acute respiratory illness in childhood has been studied in a london general practice. the total isolation rate was 31-7 per cent, but the rate varied from 32-6 per cent in upper respiratory infections to 64-0 per cent in pneumonia. the clinical features associated with infection were influenced not only by the type of agent but also by age and other host factors in infected children. rhinoviruses were more commonly isolated than any other agen ... | 1975 | 164499 |
| infectious canine hepatitis virus infections in dogs in hong kong. | | 1975 | 164711 |
| [examination of serological tests for viral diseases of the respiratory tracts in livestock. the participation of respiratory viruses in the infections and their present epizootological assessment]. | | 1975 | 164716 |
| on the pathhistologic pattern of some virus pneumonias in calves. | | 1975 | 164723 |
| immunoprophylaxis in calves against parainfluenza 3 virus and adenovirus type 4. | | 1975 | 164726 |
| active immunization against enteric and respiratory disease of cattle with bvd, ibr and adenovirus vaccines. | | 1975 | 164727 |
| [allergic reactions in viral infections]. | | 1975 | 164736 |
| colloquium on immunity to selected infectious avian diseases. epilogue. | | 1975 | 164806 |
| studies of the viral flora in keratoconjunctivitis sicca. | fifty patients suffering from kcs and exhibiting various patterns of corneal staining with fluorescein were examined for adenovirus types 3, 7, 8, and 14, herpes simplex, and the tric group by tissue culture and immunofluorescein techniques. no viruses were detected by either methods, and it is considered that presumption of virus involvement in these cases is untenable. | 1975 | 164882 |
| circulating antibodies and respiratory virus infections. | most respiratory viruses infect only the respiratory mucosa and mainly the surface epithelium, and it is therefore plausible that antibody within the circulation is unable to influence them, either by preventing infection or by terminating it once it has started. however there is experimental and observational evidence that some infections are prevented by circulating antibody. this may be because circulating immunoglobulins are released onto the surface possibly because of virus cytopathic effe ... | 1975 | 165114 |
| etiological relationship between several respiratory viruses and acute respiratory diseases in 1973 in the gdr. | the role of some important respiratory viruses (influenza a, b, parainfluenza, adeno and mycoplasma) in morbidity due to acute respiratory diseases during 1973 in the gdr is analysed on account of serological data (cfr) obtained with paired sera (a -5 percent of all cases comprising all age groups) and virus isolations. the serological surveillance provides an important base for evaluating the significance of respiratory agents for the development of the morbidity due to ard. | 1975 | 165122 |
| local and systemic response after simultaneous intranasal inoculation of temperature-sensitive mutants of parainfluenza 3, ibr and bovine adenovirus 3. | triple seronegative calves were exposed by the nasal route to three (ts) mutants of bovine respiratory viruses (pi3, ibr, adeno3). after a single exposure, they responded with significant levels of serum antibodies to the three viruses. nasal antibodies were demonstrated for pi3 and adenovirus antigens. the failure to demonstrate nasal antibodies to ibr may be due to lack of sensitivity of the procedure used. when reexposed six weeks later, calves had sharp increases in levels of serum antibodie ... | 1975 | 165126 |
| live and killed virus vaccines: their use against the respiratory diseases of cattle. | the respiratory diseases of cattle are due to a combination of different factors among which figures a viral infection. the antiviral vaccination, perfectly possible owing to associated killed vaccines and live virus, is thus a very important element which must enter into every general plan of prophylaxis. moreover, these plans will concern bacterial infections, conditions of rearing, etc. we have demonstrated that it is possible to produce good immunity in calves and sheep using a trivalent kil ... | 1975 | 165130 |
| organ culture of human aorta: prolonged survival with support of viral replication. | organ cultures were established with use of human fetal aorta obtained after death; cellular elements were preserved in the cultures for periods of up to eight weeks, with maintenance of their in vivo tissue relationships. histologically, these cultures preserve the three coats of the aorta, including an intact endothelial layer cells. the aorta organ cultures supported the replication of echovirus 11, herpes simplex virus type 1, adenovirus 2, and coxsackievirus b5 without the production of det ... | 1975 | 165246 |
| enhancement of the replication of human adenovirus in simian cells by a series of temperature-sensitive mutants of simian virus 40. | | 1975 | 165626 |
| respiratory virus infections in children hospitalized in montreal, 1968 - 1972. | | 1975 | 165872 |
| simian virus 40 dna replication, transcription, and antigen induction during infection with two adenovirus 2-sv40 hybrids that contain the entire sv40 genome. | the ad2++hey hybrid virus population produces simian virus 40 (sv40) efficiently during lytic infection, whereas ad2++ley does not, although both hybrids contain a complete sv40 genome. in this report, we demonstrate the synthesis of nonhydrid sv40 dna in ad2++hey-infected vero cells, but only early sv40 rna is transcribed efficiently in ad2++ley-infected cells. ad2++hey induces sv40 u, t, and v antigens during lytic infection of african green monkey kidney cells, whereas ad2++ley induces only s ... | 1975 | 166206 |
| complementing xeroderma pigmentosum fibroblasts restore biological activity to uv-damaged dna. | uv survival curves of adenovirus 2 using fused, complementing xeroderma pigmentosum (xp) fibroblast strains as virus hosts showed a component with an inactivation slope identical to that given by normal cells. this component was not observed when the fibroblasts were not fused or when fusion involved strains in the same complementation group. extrapolation of this component indicated that at zero dose 3% of the viral plaque-forming units had infected cells capable of normal repair. these results ... | 1975 | 166304 |
| immunofluorescent diagnosis of acute viral infection. | | 1975 | 166450 |
| enhancement of adenovirus infection in wi-38 and agmk cells by pretreatment of cells with 5-iododeoxyuridine. | | 1975 | 166491 |
| adeno-associated virus in adenovirus type 3 conjunctivitis. | although human infection with adenovirus-associated virus (aav) has been demonstrated, there is no evidence that disease results from such infections. the proportion of adenovirus infections which are dual infections with aav is virtually unknown, since special methods are required to demonstrate infection with aav. to search for aav, we re-examined a collection of specimens from 40 persons involved in an epidemic of pharyngoconjunctival fever associated with a swimming pool. virological and ser ... | 1975 | 166918 |
| control of nuclear division in sv40 and adenovirus type 12 transformed mouse 3t3 cells. | untransformed, non-tumorigenic mouse cells respond to cytochalasin b (cb) with limited nuclear division. balb/c mouse embryo fibroblasts (mef) and both balb/c 3t3 and swiss 3t3 cells become binucleated in the presence of cb and cells with three or more nuclei are very rare or undetectable. mef are diploid (40 chromosomes) and 3t3 cells are subtetraploid (74-76 chromosomes). transformation of mef by sv40 produces a dramatic change in response to cb. these cells, which contain sv40 t-antigen, beco ... | 1975 | 166945 |
| characterization of adenovirus antibodies by single radial diffusion in agarose gels containing immobilized intact virus particles. | the interaction between antibodies and surface antigens of intact immobilized adenovirus particles was studied by single radial immunodiffusion tests (srdt) in agarose gels. purified virus particles and antisera against virus particles of selected serotypes representing different subgroups and against structural components of certain serotypes were employed. antibodies against hexons, pentons and fibres all gave visible zones. antisera against the latter components were more efficient in forming ... | 1975 | 167117 |
| post-transcriptional restriction of human adenovirus expression in monkey cells. | infection of the continuous simian cell lines cv-1 and bsc-1 with human adenovirus type 2 (ad2) is abortive. however, the restriction of ad2 reproduction in these cells can be overcome by increasing the ad2 infectious dose or by coinfection with simian virus 40. vero, another established simian cell line free of detectable endogenous simian virus 40 dna, is not restricted in its ability to promote ad2 growth even at low input multiplicities of ad2 and in the absence of sv40 helper. the amount of ... | 1975 | 167185 |
| herpes simplex virus in idiopathic facial paralysis (bell palsy). | sera from all 41 adult patients with idiopathic facil paralysis (bell palsy) and 35 (85%) of 41 matched controls who had never had bell palsy contained antibodies to herpes simplex virus (p smaller than.05). the frequency of antibodies to herpes zoster virus did not differ in patients and controls. a rise in antibody titer, indicating primary herpes simplex virus infection, was not found in these patients. that bell palsy may be caused by reactivation of herpes simplex virus is suggested by (1) ... | 1975 | 167209 |
| [various methods of virologic diagnosis as applied to etiological studies on respiratory infections]. | | 1975 | 167243 |
| virus isolation and titration at 33 degrees and 37 degrees c. | various prototype viruses and original specimens were comparatively titrated in cell cultures at 33 degrees and 37 degrees c. higher titers at 37 degrees were consistently obtained with adenoviruses; for other viruses (enteroviruses, herpesvirus hominis, vaccinia virus, parainfluenza viruses) the titers were mostly identical at either temperature. original specimens and prototye strains showed the same behavior. the habit to cultivate viruses from throat swabs at 33 degrees c is unsatisfactory f ... | 1975 | 167268 |
| surveillance of enterovirus infections in bangkok. i. isolation of enterovirus from faecal specimens of healthy children. | during the period august 1970 through july 1973, about 50 faecal specimens collected each month from healthy pre-school children of lower economic status in bangkok were studied for virus isolation using primary monkey kidney cells and new born mice. from a total of 1,823 samples, 557 (30.5%) were positive: 86 (4.8%) polioviruses, 77 (4.2%) coxsackieviruses b, 223 (12.2%) echoviruses, and 127 strains (7.0%) of unidentified viruses. altogether, 45 serotypes of enteric viruses were identified. mor ... | 1975 | 167453 |
| [viruses in the etiology of diseases of the upper respiratory tracts]. | | 1975 | 167497 |
| [relation between the etiology and course of respiratory viral infections and the abo blood group system in young children]. | | 1975 | 167525 |
| an updated listing of animal reference virus recommendations. | | 1975 | 167622 |
| a bovine adenovirus type 3: isolation, characterization, and experimental infection in calves. | a virus was isolated from a group of feedlot cattle with acute respiratory disease that was characterized by physicochemical methods as an adenovirus and identified serologically as a bovine adenovirus type 3. intratracheal inoculation of three 4 month old colostrum deprived calves resulted in pyrexia, hyperpnea, dyspnea, anorexia and in one animal a mild diarrhea. | 1975 | 167684 |
| adenovirus type 19 keratoconjunctivitis in canada. | we describe an outbreak of epidemic keratoconjunctivitis occurring in montreal during the winter of 1974. adenovirus type 19 was the only virus isolated. we confirm the presence of type 19 adenovirus in canada; it produces severe keratoconjunctivitis. the incubation period, method of spread and clinical findings resemble those seen in outbreaks of type 8 ekc. the prevalence of adenovirus type 19 in the population of canada is unknown. although some object to the use of the term ekc for infection ... | 1975 | 167920 |