| the vaginal smear, mating, egg transport and preimplantation development in a wild guinea-pig, the cuis (galea musteloides). | observations were made on vaginal smear pattern, mating, rate of egg transport and preimplantation development in cuis. in 39 of 45 females (87%) vaginal opening occurred within 2 days of pairing, and in 44 (98%) within 5 days; 36 of the 44 females (82%) mated. by the morning of day 2, eggs were no longer recovered from the ampulla, having all passed into the isthmus, where they remained till day 4, p.m. uterine entry was complete by day 5, a.m. uterine blastocysts were no longer recoverable on ... | 1979 | 571471 |
| the effects of age and anaesthetic on the blood picture of the cuis, galea musteloides. | blood samples from 25 adult and 6 immature cuis were examined. there were slight differences in red cell parameters (rbc, hb, pcv, mcv, mch, & mchc) between cuis and guinea-pigs. the total white cell count of cuis was much lower. the neutrophils of the cuis, as of the guinea-pig, had eosinophilic granules and were therefore termed pseudoeosinophils. kurloff bodies were not present in mononuclear cells. there were more platelets in cuis blood compared with guinea-pig blood. the choice of anaesthe ... | 1976 | 966696 |
| nickel nitrate: a new junction permeability tracer for the study of the blood-testis barrier. | with the purpose of evaluating a new intercellular tracer, nickel-k ferrocyanide, we compared results yielded by lanthanum with information provided by nickel. this was done in the seminiferous epithelium of holtzman rats of several postnatal ages and in a wild local seasonal breeder galea musteloides. tissues were studied with transmission electron microscopy and freeze-fracture replications. nickel tracing proved to delineate cell contours more intensely and less interruptedly than lanthanum. ... | 1992 | 1611149 |
| axenic isolation of giardia strains from primates and rodents. | during the examination of animals at the poznan zoological gardens, attempts were made to isolate giardia strains. using an in vitro excystation procedure, eight samples of cysts from animals with asymptomatic giardiasis were inoculated on bi-s-33 medium. the ease of isolation and axenization of giardia was surprising; five axenic isolates of giardia, belonging to the g. duodenalis morphological group, were established from primates (slow loris, lesser slow loris and siamang) and from rodents (g ... | 1990 | 2343527 |
| molecular evolution of rodent insulins. | several trees of amino acid sequences of rodent insulins were derived with the maximum-parsimony procedure. possible orthologous and paralogous relationships were investigated. except for a recent gene duplication in the ancestor of rat and mouse, there are no strong arguments for other paralogous relationships. therefore, a tree in agreement with other biological data is the most reasonable one. according to this tree, the capacity to form zinc-binding hexamers was lost once in the ancestor of ... | 1987 | 3328814 |
| the role of the male in the evocation of oestrus in the cuis, galea musteloides (rodentia: hystricomorpha). | | 1973 | 4522390 |
| steroid metabolism by the chin gland of the male cuis, galea musteloides. | | 1973 | 4699447 |
| progesterone levels during the oestrous cycle and pregnancy in the cuis, galea musteloides. | | 1973 | 4742149 |
| the evocation of oestrus in the cuis, galea musteloides. | | 1971 | 5106118 |
| progesterone-binding proteins in plasma of guinea-pigs and other hystricomorph rodents. | progesterone-binding plasma proteins (pbpp, progesterone-binding globulin, pbg, and corticosteroid binding globulin, cbg) have been measured in plasma of guinea-pigs, casiragua, cuis, degu and plains viscacha. during pregnancy pbpp increased to reach peak values between days 20-25 and days 50-term in guinea-pigs, immediately before parturition in casiragua, and in mid-gestation in cuis, degu and viscacha. the pattern of pbpp concentration during pregnancy was similar to that of plasma progestero ... | 1981 | 6170753 |
| origin of the duplicated ribonuclease gene in guinea-pig: comparison of the amino acid sequences with those of two close relatives: capybara and cuis ribonuclease. | the amino acid sequences of the pancreatic ribonuclease from capybara (hydrochoerus hydrochaeris) and cuis (galea musteloides) were determined. both species belong to the same superfamily of the hystricomorph rodents as the guinea-pig. in guinea-pig pancreas two ribonucleases are present as a result of a recent gene duplication, but in capybara and cuis pancreas only one single ribonuclease has been found. a most parsimonious tree of ribonucleases indicates that the gene duplication leading to b ... | 1983 | 6571219 |
| glucagon of caviomorphs and other tetrapods immunohistochemically investigated with two antisera against the n- and c-terminal portions of the molecule. | pancreatic sections from diverse tetrapods, including various species of caviomorph rodents, were immunohistochemically investigated using two antisera which reacted with the n- and c-terminal portions of the glucagon molecule. while the antiserum against the n-terminal portion stained alpha cells in all the species studied, the antiserum against the c-portion failed to stain alpha cells in two caviomorphs of the caviidae family (guinea pig and cuis) and in one of the octodontidae family (degu). ... | 1995 | 8536927 |
| of domestic and wild guinea pigs: studies in sociophysiology, domestication, and social evolution. | among mammals a majority of each individual's daily expectations, motivations, and behaviors are directed to encounters with conspecifics. therefore the knowledge of the genesis, control, and consequences of social interactions is crucial for understanding their social life. we present here our research on the sociophysiology, domestication, and social evolution of wild (cavia aperea and galea musteloides) and domestic (cavia aperea f. porcellus) guinea pigs, which summarizes general rules for m ... | 1998 | 9722963 |
| maturation of epididymal spermatozoa in the nondomesticated guinea pigs cavia aperea and galea musteloides. | the physiological changes occurring in spermatozoa in the male reproductive tract of 2 nondomesticated species of south american guinea pigs with different mating systems were studied. cavia aperea, the wild ancestor of the domesticated guinea pig, has a polygynous mating system, whereas galea musteloides exhibits promiscuous mating behavior. the epididymis of both species resembled that of the domesticated guinea pig, with a swathe of tubule convolutions (linking the 2 major parts of the organ) ... | 2000 | 10670529 |
| surface emg-recordings using a miniaturised matrix electrode: a new technique for small animals. | a new method for multichannel surface-emg measurements in small animals is presented. the underlying scientific aim is the characterisation of the spreading and the co-ordination of skeletal muscle activation between different muscles or muscle parts, depending on various motor tasks. the myoelectrical signals were recorded monopolarly by a 16-channel matrix electrode on the muscle surface directly under the skin on the fascia of the investigated muscle, without damaging the muscle. surface-emg' ... | 2000 | 10771077 |
| lung morphology in rodents (mammalia, rodentia) and its implications for systematics. | a new nomenclature of the lung lobes and of the bronchial tree is presented, with which the lungs in 40 species of 11 rodent families are described. whole, fixed lungs and silicone casts of the bronchial tree are tested for 23 characters, based on the distribution of lung lobes, the number and geometry of first order bronchi, the pulmonary blood supply, and lung symmetry. ten lung morphotypes are recognized, seven of them representing one or more families: castor type (castoridae), cryptomys typ ... | 2000 | 11077434 |
| different types of oestrous cycle in two closely related south american rodents (cavia aperea and galea musteloides) with different social and mating systems. | a comparative approach was used to investigate two closely related south american rodent species: the wild cavy (cavia aperea) and the yellow-toothed cavy (galea musteloides). these species of wild guinea-pig inhabit different habitats and show divergent social and mating systems. cavia have a polygynous mating system, whereas in galea promiscuous mating occurs. these observations correspond to functional variations in sperm characteristics, which might be interpreted as adaptations to different ... | 2001 | 11427168 |
| torque patterns of the limbs of small therian mammals during locomotion on flat ground. | in three species of small therian mammals (scandentia: tupaia glis, rodentia: galea musteloides and lagomorpha: ochotona rufescens) the net joint forces and torques acting during stance phase in the four kinematically relevant joints of the forelimbs (scapular pivot, shoulder joint, elbow joint, wrist joint) and the hindlimbs (hip joint, knee joint, ankle joint, intratarsal joint) were determined by inverse dynamic analysis. kinematics were measured by cineradiography (150 frames s(-1)). synchro ... | 2002 | 11948209 |
| monogamy in a new species of wild guinea pigs (galea sp.). | a new species of wild guinea pigs from bolivia was recently discovered: galeasp. so far no data are available concerning its social and mating systems. we therefore investigated behavioural compatibility, sexual dimorphism, paternity in a male-competing situation, testicular and epididymal size, and sperm morphology and motility. the results showed a complete intrasexual and moderate intersexual behavioural incompatibility between unfamiliar animals, a reversed sexual dimorphism with females lar ... | 2002 | 12384721 |
| amblyomma tigrinum (acari: ixodidae): new data on hosts and biology of immature stages and on dna composition. | biological data of immature stages of amblyomma tigrinum were obtained from larvae and nymphs both fed on rats and rabbits. data from nymphs recovered from a wild rodent (galea musteloides) are also reported. additional results in dna composition of males moulted from nymphs fed on laboratory and wild hosts are presented. the ticks were maintained in darkness at 27 +/- 1 degrees c and 83-86% rh. the mean recovery rates were 49.1% and 43.6% with a moulting success of 96.2% and 90.8% in larvae fed ... | 2005 | 16143451 |
| the natural hosts of larvae and nymphs of amblyomma tigrinum koch, 1844 (acari: ixodidae). | the hosts of larvae and nymphs of amblyomma tigrinum, a tick whose adults feed on wild and domestic canidae in south america, are uncertain. a 17 months survey was carried out trapping wild vertebrates in north-western córdoba, argentina, to evaluate their parasitism with a. tigrinum subadults. larvae and nymphs of this tick species were identified conventionally and by comparison of 16s rdna sequences with genbank deposited sequences. a total of 207 small and medium-sized rodents and 182 birds ... | 2006 | 16682121 |
| the natural hosts for larvae and nymphs of amblyomma neumanni and amblyomma parvum (acari: ixodidae). | based on the hypothesis that birds and rodents are important hosts for subadults of the neotropical amblyomma neumanni and amblyomma parvum ticks, a survey of these type of hosts was carried out from july 2004 to march 2006, in quilino (a. parvum) and dean funes (a. neumanni), córdoba province, argentina. additionally, monthly tick counts were performed on cattle and goats with occasional tick search in other domestic hosts. records of questing height of subadult ticks on vegetation were also ca ... | 2006 | 17006739 |
| aspects of the life cycle of amblyomma parvum (acari: ixodidae) under natural conditions. | monthly samplings of the rodent galea musteloides (caviidae) were carried out from january 2005 to december 2006 in quilino, córdoba province, argentina, to determine the seasonal distribution of immature stages of amblyomma parvum. in the same locality, cattle and goats were also monthly examined to asses the seasonality of the females of this species. engorged ticks collected on their natural hosts were maintained in the laboratory at 25 degrees c and 83-86% relative humidity to study biologic ... | 2008 | 18620813 |
| carbonic anhydrase variation in the cuis (galea musteloides). | | 2014 | 4119241 |
| population and genetic outcomes 20 years after reintroducing bobcats (lynx rufus) to cumberland island, georgia usa. | in 1988-1989, 32 bobcats lynx rufus were reintroduced to cumberland island (cuis), georgia, usa, from which they had previously been extirpated. they were monitored intensively for 3 years immediately post-reintroduction, but no estimation of the size or genetic diversity of the population had been conducted in over 20 years since reintroduction. we returned to cuis in 2012 to estimate abundance and effective population size of the present-day population, as well as to quantify genetic diversity ... | 2015 | 26640668 |
| blood meal sources of wild and domestic triatoma infestans (hemiptera: reduviidae) in bolivia: connectivity between cycles of transmission of trypanosoma cruzi. | chagas disease is a major public health problem in latin america. its etiologic agent, trypanosoma cruzi, is mainly transmitted through the contaminated faeces of blood-sucking insects called triatomines. triatoma infestans is the main vector in various countries in south america and recently, several foci of wild populations of this species have been described in bolivia and other countries. these wild populations are suspected of affecting the success of insecticide control campaigns being car ... | 2016 | 27090297 |
| developing an algorithm to detect early childhood obesity in two tertiary pediatric medical centers. | the objective of this study is to develop an algorithm to accurately identify children with severe early onset childhood obesity (ages 1-5.99 years) using structured and unstructured data from the electronic health record (ehr). | 2016 | 27452794 |
| clinical utility of a single-item test for dsm-5 alcohol use disorder among outpatients with anxiety and depressive disorders. | there is a lack of studies testing accuracy of fast screening methods for alcohol use disorder in mental health settings. we aimed at estimating clinical utility of a standard single-item test for case finding and screening of dsm-5 alcohol use disorder among individuals suffering from anxiety and mood disorders. | 2016 | 27318372 |
| an ir-based approach utilising query expansion for plagiarism detection in medline. | the identification of duplicated and plagiarised passages of text has become an increasingly active area of research. in this paper we investigate methods for plagiarism detection that aim to identify potential sources of plagiarism from medline, particularly when the original text has been modified through the replacement of words or phrases. a scalable approach based on information retrieval is used to perform candidate document selection - the identification of a subset of potential source do ... | 2016 | 26992177 |
| normalizing clinical terms using learned edit distance patterns. | variations of clinical terms are very commonly encountered in clinical texts. normalization methods that use similarity measures or hand-coded approximation rules for matching clinical terms to standard terminologies have limited accuracy and coverage. | 2016 | 26232443 |
| frequency analysis of medical concepts in clinical trials and their coverage in mesh and snomed-ct. | eligibility criteria (ec) of clinical trials play a key role in selecting appropriate study candidates and the validity of the outcome of a clinical trial. however, in most cases ec are provided in unstandardised ways such as free text, which raises significant challenges for machine-readability. | 2015 | 25346408 |
| multi-topic assignment for exploratory navigation of consumer health information in netwellness using formal concept analysis. | finding quality consumer health information online can effectively bring important public health benefits to the general population. it can empower people with timely and current knowledge for managing their health and promoting wellbeing. despite a popular belief that search engines such as google can solve all information access problems, recent studies show that using search engines and simple search terms is not sufficient. our objective is to provide an approach to organizing consumer healt ... | 2014 | 25086916 |
| a semantic-based approach for exploring consumer health questions using umls. | netwellness is a non-profit web service providing high quality health information. it has been in operation since 1995 with over 13 million visits per year by consumers across the world in recent years. consumer questions in netwellness have been answered by medical and health professional faculties at three ohio partner universities: case western reserve university, the ohio state university, and university of cincinnati. however, the resident interface in netwellness is ineffective in searchin ... | 2014 | 25954347 |
| dissociation of the x chromosome from the synaptonemal complex in the xy body of the rodent galea musteloides. | the xy body from spermatocytes of the rodent galea musteloides shows progressive changes of the synaptonemal complex (sc) axes and the x-chromatin during pachynema. there is a gross thickening of the x-axis and the formation of a large x chromosome loop at mid and late pachytene stages. the sc proteins synaptonemal complex protein 3 (sycp3), synaptonemal complex protein 1, and synaptonemal complex central element protein 3 and the proteins breast cancer 1, mutl homolog 1 (mlh1), and radiation-re ... | 2013 | 24043547 |
| using umls concept unique identifiers (cuis) for word sense disambiguation in the biomedical domain. | this paper explores the use of concept unique identifiers (cuis) as assigned by metamap as features for a supervised learning approach to word sense disambiguation of biomedical text. we compare the use of cuis that occur in abstracts containing an instance of the target word with using the cuis that occur in sentences containing an instance of the target word. we also experiment with frequency cutoffs for determining which cuis should be included as features. we find that a naive bayesian class ... | 2007 | 18693893 |
| exploratory and confirmatory factor analysis of the child uncertainty in illness scale among children with chronic illness. | to conduct an exploratory factor analysis (efa) and a confirmatory factor analysis (cfa) of the child uncertainty in illness scale (cuis) with a sample of children and adolescents with a chronic health condition. developmental differences in factor structure were also examined. | 2007 | 16840791 |
| postnatal allometry of the skeleton in tupaia glis (scandentia: tupaiidae) and galea musteloides (rodentia: caviidae)--a test of the three-segment limb hypothesis. | during the evolution of therian mammals, the two-segmented, sprawled tetrapod limbs were transformed into three-segmented limbs in parasagittal zig-zag configuration (three-segment limb hypothesis). as a consequence, the functional correspondence of limb segments has changed (now: scapula to thigh, upper arm to shank, fore arm plus hand to foot). therefore, the scapula was taken into account in the current study of the postnatal growth of the postcranial skeleton in two small mammalian species ( ... | 2006 | 16600582 |
| ontogenetic development of locomotion in small mammals--a kinematic study. | comparative studies of locomotion indicate that limb design and performance are very similar in adult mammals of small to medium size. the present study was undertaken to test whether basic therian limb pattern is present during postnatal development. kinematic data were collected from juveniles of two eutherian species in a cross-sectional study, using cinevideography. the tree shrew tupaia glis and the cui galea musteloides were selected because of their different reproductive strategies, whic ... | 2005 | 16244162 |
| [antibacterial therapy of complicated urinary infections in outpatients]. | the term complicated urinary infections (cuis) includes infections developing in the presence of anatomic anomalies, metabolic or hormonal disorders, immunodeficiency or infection with atypical microorganisms. complicating factors diminish efficiency of antibiotic treatment, raise probability of recurrence. cuis account for 45.2% of all cases of outpatient urinary infections in adults in russia. nephroliths, diabetes mellitus and renal cysts are most prevalent complicating factors. cuis causativ ... | 2008 | 15560157 |
| tracking meaning over time in the umls metathesaurus. | the unified medical language system(r) (umls) metathesaurus contains records arranged by concept or meaning. each concept contains a unique identifier (cui) that can be used to track the concept over time. since the january 2001 release, the metathesaurus has included the file mrcui that contains mappings for cuis that disappear. this paper describes the processes that facilitated this effort and the ongoing effort to find suitable mappings for concepts whose meanings no longer exist in the meta ... | 2002 | 12463898 |
| an international dermatological image atlas on the www: practical use for undergraduate and continuing medical education, patient education and epidemiological research. | we describe the development of an image database doia (dermatological online atlas) and present several spin-off projects using images of the atlas, e.g. student education using the atlas including results of an questionnaire evaluating computer-literacy, prerequisites and interests of students for using computers and the world-wide-web (www), a patient information system and an experiment to collect epidemiological data from patients with dermatological diseases via www. the database, available ... | 1998 | 10384570 |
| musc information system ariadne: a consistent tool for support of experiment planning, execution and scientific evaluation of microgravity-experiments. | one of the main tasks of dlr-musc (microgravity user support center) is to accompany an experiment's complete life-cycle, thus supporting the investigators. this task starts with the preparation of experiments, continues with their execution and finally leads to the evaluation of the respective measurement results. a computer-based information system facilitates these tasks. considerable effort has been taken in order to make a detailed as well as modular design--as a result the system can now b ... | 1992 | 11537582 |
| postnatal development of the testes in the cuis, galea musteloides. | testicular development to 9 months of age has been studied. seminiferous tubule diameter increased in a linear manner between 13 and 65 days of age, and there was a steep increase in testicular weight with age. at about 9 months the animals weighed 400-500 g and total testicular weight was about 10 g. this relatively large testicular size was correlated with high sperm density in the semen. spermatogenesis commenced at about 21-25 days of age, when the first spermatids were found. spermatozoa ap ... | 1977 | 865075 |
| the use of an image analyser for measuring the cross-sectional area of leydig cells in the testis of the cuis (galea musteloides). | | 1976 | 787823 |
| the ultrastructure and histochemistry of the chin gland of the cuis, galea musteloides. | | 1973 | 4719658 |
| cuiless2016: a clinical corpus applying compositional normalization of text mentions. | traditionally text mention normalization corpora have normalized concepts to single ontology identifiers ("pre-coordinated concepts"). less frequently, normalization corpora have used concepts with multiple identifiers ("post-coordinated concepts") but the additional identifiers have been restricted to a defined set of relationships to the core concept. this approach limits the ability of the normalization process to express semantic meaning. we generated a freely available corpus using post-coo ... | 2018 | 29316970 |
| irrigation effectiveness of continuous ultrasonic irrigation system: an ex vivo study. | this study evaluated the irrigation extrusion and smear layer (sl) removal of continuous ultrasonic irrigation (cui). forty root canals were shaped, embedded in warm sterile saline agar colored with 1% acid red, and distributed into four groups; three groups had the final irrigation sequence of sodium hypochlorite and edta solutions performed by using syringe irrigation (si), endovac (ev), and cui, respectively. group 4 had the canals ultrasonically irrigated with saline (cuis). irrigant extrusi ... | 2017 | 28883300 |
| analysis of annotated data models for improving data quality. | the public medical data models (mdm) portal with more than 9.000 annotated forms from clinical trials and other sources provides many research opportunities for the medical informatics community. it is mainly used to address the problem of heterogeneity by searching, mediating, reusing, and assessing data models, e. g. the semi-interactive curation of core data records in a special domain. furthermore, it can be used as a benchmark for evaluating algorithms that create, transform, annotate, and ... | 2017 | 28883198 |
| word2vec inversion and traditional text classifiers for phenotyping lupus. | identifying patients with certain clinical criteria based on manual chart review of doctors' notes is a daunting task given the massive amounts of text notes in the electronic health records (ehr). this task can be automated using text classifiers based on natural language processing (nlp) techniques along with pattern recognition machine learning (ml) algorithms. the aim of this research is to evaluate the performance of traditional classifiers for identifying patients with systemic lupus eryth ... | 2017 | 28830409 |
| impact of non-pharmaceutical interventions on the incidence of respiratory infections during the covid-19 outbreak in korea: a nationwide surveillance study. | many countries have implemented non-pharmaceutical interventions (npis) to slow the spread of coronavirus disease 2019 (covid-19). we aimed to determine whether npis led to the decline in the incidences of respiratory infections. | 2020 | 33150393 |
| prediction of severe chest injury using natural language processing from the electronic health record. | trauma injury severity scores are currently calculated retrospectively from the electronic health record (ehr) using manual annotation by certified trauma coders. natural language processing (nlp) of clinical documents in the ehr may enable automated injury scoring. we hypothesize that nlp with machine learning can discriminate between cases of severe and non-severe injury to the thorax after trauma. | 2020 | 33131794 |
| perceived stigma, illness uncertainty, and depressive symptoms in youth with inflammatory bowel disease: the moderating effect of mindfulness. | perceived illness stigma is associated with increased depressive symptoms in youth with inflammatory bowel disease (ibd), but the mechanisms by which stigma influences emotional adjustment remain unclear. it is possible that youth with ibd who are more present-focused and better able to come to terms with aspects of their disease that are less controllable (i.e. are mindful) may develop more adaptive strategies when facing illness uncertainty, resulting in more positive emotional adjustment. the ... | 2020 | 31941362 |
| a new index of clinical utility for diagnostic tests. | clinical utility of a diagnostic test depends on its diagnostic accuracy, the pretest probability of disease and the clinical consequences of the test results. tools for evaluating clinical utility are scarce. we propose a new clinical utility index (cui), which is the expected gain in utility (egu) of the test divided by the egu of an ideal test, both adjusted for egu of the optimal clinical action without testing. the index expresses the relative benefit of using the test compared to using an ... | 2019 | 31675254 |
| development and application of a high throughput natural language processing architecture to convert all clinical documents in a clinical data warehouse into standardized medical vocabularies. | natural language processing (nlp) engines such as the clinical text analysis and knowledge extraction system are a solution for processing notes for research, but optimizing their performance for a clinical data warehouse remains a challenge. we aim to develop a high throughput nlp architecture using the clinical text analysis and knowledge extraction system and present a predictive model use case. | 2019 | 31145455 |
| clinical text classification with rule-based features and knowledge-guided convolutional neural networks. | clinical text classification is an fundamental problem in medical natural language processing. existing studies have cocnventionally focused on rules or knowledge sources-based feature engineering, but only a limited number of studies have exploited effective representation learning capability of deep learning methods. | 2019 | 30943960 |
| can automated retrieval of data from emergency department physician notes enhance the imaging order entry process? | when a paucity of clinical information is communicated from ordering physicians to radiologists at the time of radiology order entry, suboptimal imaging interpretations and patient care may result. | 2019 | 30895573 |
| physician nurse care: a new use of umls to measure professional contribution: are we talking about the same patient a new graph matching algorithm? | physician and nurses have worked together for generations; however, their language and training are vastly different; comparing and contrasting their work and their joint impact on patient outcomes is difficult in light of this difference. at the same time, the ehr only includes the physician perspective via the physician-authored discharge summary, but not nurse documentation. prior research in this area has focused on collaboration and the usage of similar terminology. | 2018 | 29602435 |