Publications

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temporal, spatial, and ecological modes of evolution of eurasian mus based on mitochondrial and nuclear gene sequences.we sequenced mitochondrial (cytochrome b, 12s rrna) and nuclear (irbp, rag1) genes for 17 species of the old world murine genus mus, drawn primarily from the eurasian subgenus mus. phylogenetic analysis of the newly and previously available sequences support recognition of four subgenera within mus (mus, coelomys, nannomys, and pyromys), with an unresolved basal polytomy. our data further indicate that the subgenus mus contains three distinct 'species groups': (1) a mus booduga species group, al ...200415522792
polymorphism of the murine inhibitor of differentiation-controlling gene, id.the structure of id was examined by southern analysis in inbred mouse lines which included five subspecies of mus musculus. no variation was detected within this species. the species mus cookii shares the same form found in mice of m. musculus derivation, indicative of a long evolutionary history and a common origin. however, five taqi polymorphisms were found among several mus species, suggesting that id has been modified throughout species diversification. whether these variants impart functio ...19957875604
use of monoclonal antibodies to define the diversity of mammary tumor viral gene products in virions and mammary tumors of the genus mus.monoclonal antibodies have been generated against disrupted mammary tumor viruses isolated from mus musculus, mus cervicolor, and mus cookii. monoclonal antibodies directed against the m.w. 36,000 external glycoproteins of these viruses demonstrate the presence of multiple epitopes, i.e., distinct antigenic determinants, within these glycoproteins. these epitopes represent type, group, and interspecies determinants. monoclonal antibodies have also been used to define multiple epitopes on the m.w ...19816163523
recent evolutionary origin of the expression of the glial fibrillary acidic protein (gfap) in lens epithelial cells. a molecular and genetic analysis of various mouse species.we have investigated the phylogenetic distribution of the glial fibrillary acidic protein (gfap) in lens epithelial cells (lec) of various mouse species within the genus mus. we have shown that lens gfap is expressed in mice of the mus musculus complex and in mus spicilegus and mus macedonicus species (l.gfap(+) phenotype) while it is absent in mus spretus, mus caroli and mus cooki species (l.gfap(-) phenotype). our results argue in favour of one of the phenograms illustrating the probable phylo ...19911712888
genetic variation in mouse apolipoprotein a-iv due to insertion and deletion in a region of tandem repeats.we have detected three unique apolipoprotein a-iv (apoa-iv) charge isoforms in strains of commensal mice. the cdna sequences for one representative of each isoform (mus domestesticus strains c57bl/6j and 129/j and mus castaneus) revealed a polymorphism within a series of four imperfect repeats encoding the sequence glu-gln-ala/val-gln. insertions or deletions of 12 nucleotides within this repetitive region have given rise to three genotypes characterized by three (129), four (c57bl/6), or five ( ...19911648102
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