Publications

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comparison of yearly prevalences of echinococcus multilocularis leuckart 1863 in peromyscus maniculatus and microtus pennsylvanicus in north dakota. 19751104799
experimental meningoencephalitis in trypanosoma brucei infection of deer mice (peromyscus maniculatus). a light, immunofluorescent, and electron microscopic study. 1977331839
immunosuppression in deer mice with experimentally induced trypanosomiasis.light and electron microscopic examinations of deer mice (peromyscus maniculatus) chronically infected with trypanosoma equiperdum revealed hyperplasia of germinal center lymphocytes (germanocytes) in the lymph follicles of spleen and lymph nodes and infiltration of the splenic red pulp cords and nodal medullary cords with plasma cells. proliferation and infiltration of plasma cells caused disruption of the b- and t-lymphocyte areas in these organs. stimulation of splenic lymphocytes in vitro by ...1977327872
hereditary cataracts in deer mice (peromyscus maniculatus).a new type of hereditary cataract was predicted in the deer mouse (peromyscus maniculatus) by the presence of syndactyly of the hind feet. early morphologic changes were found in the equatorial cells that differentiated into new lens fibers. later swelling at the anterior and posterior poles of these cells produced lens opacities. anterior and posterior subcapsular cataracts progressed to a hypermature shrunken lens.1975169695
meningoencephalitis in trypanosoma equiperdum infection of deer mice (peromyscus maniculatus). 1977838897
rodent models of the human isoniazid-acetylator polymorphism.inbred strains and subpopulations of rats, laboratory mice, and deer mice were examined for individual variation in the ability to metabolize several arylamines (p-aminobenzoic acid, sulfamethazine, aniline, alpha-naphthylamine, and aminofluorene) by n-acetylation. individual differences within species were found to be dependent upon the tissue source of n-acetyltransferase activity and the acetyl acceptor employed. long-evans rats possessed about 2-fold more p-aminobenzoic acid n-acetyltransfer ...197940765
a soluble immunosuppressor substance in spleen in deer mice infected with trypanosoma brucei.a soluble substance that blocks b-cell response was extracted from spleen of deer mice (peromyscus maniculatus) chronically infected with trypanosoma brucei. immunosuppressor activity of this substance was demonstrated by plaque-forming cell assays of spleen cells from swiss/webster mice inoculated with sheep red blood cells and simultaneously given the suppressor substance, and of spleen cell cultures treated with sheep red blood cells and suppressor substance. studies by light and electron mic ...1979316660
cataract--webbed peromyscus. i. genetics of cataract in p. maniculatus.cataract--webbed (cw) in the deer mouse (peromyscus maniculatus) is a recessive mutant that is manifested by syndactyly (involving soft tissues) and eye defects including cataract. within cw/cw mice, the age at which cataract first appears is genetically controlled. evidence for the activity of genetic modifiers is the early appearance of cataracts in the offspring of parents that developed cataracts at early ages.1979469220
on the occurrence of microsporum persicolor in montreal, canada.a case of microsporum persicolor skin infection in a casual employee of a veterinary clinic in montreal, quebec, canada, is reported. a survey of 80 wild rodents in the montreal area resulted in the isolation of m. persicolor from two voles (clethrionomys gapperi) and one deer mouse (peromyscus maniculatus). one of the voles, heavily infested with parasites including ticks, had obvious lesions on the nose. this is the first report of m. persicolor in rodents in north america.1978714147
ultrastructural and immunological aspects of the phagocytosis of trypanosoma brucei by mouse peritoneal macrophages.trypanosome-activated mouse peritoneal macrophages phagocytized and digested trypanosoma brucei in vitro and in vivo, but in the absence of specific antiserum and complement the degree of phagocytosis was minimal. ultrastructurally, the parasites attached to the macrophage by their flagella, and ingestion proceeded flagellum first. once ingested, t. brucei was degraded, presumably due to fusion of the parasite-containing phagosome with lysosomes. contrariwise, normal mouse peritoneal macrophages ...1978640740
poison-based taste aversion learning in deer mice (peromyscus maniculatus bairdi).a series of experiments tested the ability of mice of the native genus peromyscus to form learned taste aversions. it was found that (a) the mice acquired a strong aversion after a single flavor/toxicosis pairing, (b) naive mice drinking a licl solution apparently began to experience toxic effects within 90 sec after the beginning of consumption, (c) the mice acquired a total aversion after a single flavor/delayed illness pairing when high doses of toxin were employed, and (d) the aversion produ ...1978690287
genetic variation of amylases in deer mice.the inheritance of salivary amylase variants in the deer mouse, peromyscus maniculatus, is controlled by codominant alleles, amy-1a, amy-1b, and amy-1c, at a single autosomal locus. pancreatic amylases were invariant and unaffected by salivary amylase genotypes. salivary amylase zymograms of five myomorphic rodents are compared and evolutionary implications are discussed.1977599282
genetics of hemoglobin in the deer mouse, peromyscus maniculatus. ii. multiple alleles at regulatory loci.deer mice are polymorphic for electrophoretic hemoglobin phenotypes showing one, two, or three bands. within the multibanded phenotypes, there is considerable variation in the hemoglobin partitioning, defined as the fraction of total hemoglobin made up by the secondary and tertiary bands. in subspecies sonoriensis, for example, hemoglobin partitionings range from 0.03 to 0.38. the inheritance of partitioning values is under remarkably strict genetic control. the genetic variation is additive and ...1978669256
genetics of hemoglobin in the deer mouse, peromyscus maniculatus. i. multiple alpha- and beta-globin structural loci.genetic data, together with molecular structure studies, have demonstrated that the complex hemoglobin phenotypes in four subspecies of p. maniculatus are generated by at least four, and probably five, globin structural loci. the hba and hbc loci apparently arose by duplication of an ancestral alpha-type locus, while hbb, hbd, and hbe apparently were derived from a beta-type locus. the hba and hbb structural loci are electrophoretically monomorphic, while hbc, hbd, and hbe are each polymorphic f ...1978669255
sodium pentobarbital induced alterations in regional distribution of blood in peromyscus maniculatus (deer mouse) and eptesicus fuscus (big brown bat). 1977606346
the effects of indomethacin on plasma lh levels in female and male deermice (peromyscus maniculatus).the purpose of this investigation was to determine (1) the approximate time of the preovulatory lh rise in cyclic deermice, (2) the effect of indomethacin administration on plasma lh levels during the expected preovulatory lh rise, and (3) the effect of indomethacin administration on plasma lh levels in castrated male deermice. the data indicate that the preovulatory lh rise occurred at about 2200 h on proestrus and that indomethacin pretreatment significantly reduced plasma lh levels during tha ...1979575227
factors associated with the mass of venom expended by prairie rattlesnakes (crotalus v. viridis) feeding on mice.the purpose of this study was to assess through correlation analyses the various factors and consequences associated with the mass of venom injected by prairie rattlesnakes (crotalus v. viridis) into their natural prey, deer mice (peromyscus maniculatus). fifty-seven predator-prey interactions were studied via slow motion videotape review. the mass of venom expended by snakes during biting was quantified by enzyme-linked immunosorbent assay (elisa) of whole-animal homogenates. the quantity of ve ...19921626326
uptake of environmental contaminants by small mammals in pickleweed habitats at san francisco bay, california.small mammals were live-trapped in pickleweed (salicornia virginica) habitats near san francisco bay, california in order to measure the uptake of several contaminants and to evaluate the potential effects of these contaminants on the endangered salt marsh harvest mouse (reithrodontomys raviventris). tissues of house mice (mus musculus), deer mice (peromyscus maniculatus), and california voles (microtus californicus) from nine sites were analyzed for chemical contaminants including mercury, sele ...19921586203
seasonal prevalence of taenia taeniaeformis: relationship to age, sex, reproduction and abundance of an intermediate host (peromyscus maniculatus).livers from 4,501 deer mice (peromyscus maniculatus) collected from a weedy habitat in northeastern california during 48 consecutive monthly samplings were examined microscopically for taenia taeniaeformis larva. although there were pronounced seasonal fluctuations in host density, there were no significant annual or season-related differences in cestode intensities in adult deer mice. there were no significant differences in prevalences associated with sex of the host, nor were there significan ...19921548801
cotton rats and other small mammals as hosts for immature dermacentor variabilis (acari: ixodidae) in central oklahoma.eight species of small mammals were evaluated as potential hosts for american dog ticks, dermacentor variabilis (say), in an upland, tallgrass prairie study site in central oklahoma. only hispid cotton rats, sigmodon hispidus, and deer mice, peromyscus maniculatus, were found to be important hosts for immature d. variabilis. although d. varibilis larvae and nymphs frequently infested both cotton rats and deer mice, cotton rats were the most important host species for both immature stages in the ...19921404263
native resistance of peromyscus maniculatus to nematospiroides dubius infection. 19761253923
new host and locality records of coccidia (apicomplexa: eimeriidae) from rodents in the southwestern and western united states.one hundred forty-seven murid and heteromyid rodents were collected from various sites in the southwestern and western united states (arizona, colorado, new mexico, texas, and utah) and baja california norte, mexico, and their feces were examined for coccidial parasites. of these, 53 (36%) were infected with at least 1 coccidian; 45 of 53 (85%) of the infected rodents harbored only 1 species of coccidian. infected rodents included: 10 of 22 (45%) neotoma albigula, 3 of 11 (27%) neotoma floridana ...19911779282
breeding and reproduction of fifteen wild rodents maintained as laboratory colonies.data on reproduction and production were presented for laboratory colonies of microtus pennsylvanicus tananaensis, m oeconomus macfarlani, m o operarius, m mirurus, m abbreviatus, lemmus lemmus, l sibiricus trimucronatus, dicrostonyx stevensoni, clethrionomys rutilus, peromyscus maniculatus borealis, p m bairdii, baiomys taylori, calomys ducilla, c callosus, acomys cahirinus. litter size varied from 2.0 in a cahirinus to 5.5 in c callosus. infant (neonatal) and juvenile losses through the end of ...1976775192
vertical distribution of soil removed by four species of burrowing rodents in disturbed and undisturbed soils.burrow volumes were determined in disturbed and undisturbed soils for four species of rodents in southeastern idaho. comparisons were made between soil types for the average volume and the proportion of the total volume of soil excavated from 10-cm increments for each species, and the relative number of burrows and proportion of total soil removed from beneath the minimum thickness of soil covers over buried low-level radioactive wastes. burrows of montane voles (microtus montanus) and deer mice ...19883280518
survey for ixodes spp. and borrelia burgdorferi in southeastern wisconsin and northeastern illinois.forested areas adjacent to milwaukee, wis., and chicago, ill., were investigated for rodents and ticks infected with borrelia burgdorferi, the causative agent of lyme disease. white-footed mice (peromyscus leucopus or peromyscus maniculatus), meadow voles (microtus pennsylvanicus), and eastern chipmunks (tamias striatus) were captured; and specimens from these animals were cultured for b. burgdorferi to define whether the midwestern lyme disease area currently encompasses these large metropolita ...19912007650
oxidoreduction of butanol in deermice (peromyscus maniculatus) lacking hepatic cytosolic alcohol dehydrogenase.in view of conflicting information in the literature regarding enzyme systems responsible for alcohol oxidation in deermice previously reported to lack hepatic alcohol dehydrogenase (adh) activity, the reversibility of butanol oxidation was studied in vivo and in liver-perfusion systems. mixtures of [1,1-2h2]ethanol and butanol were given intraperitoneally to deermice lacking (adh-) or possessing (adh+) adh activity, followed by analysis of alcohols in blood by gc/ms. 2h exchange between the two ...19921740147
adiaspiromycosis in the franklin's ground squirrel, spermophilus franklini, and pika, ochotona princeps, from alberta, canada.pulmonary adiaspiromycosis due to emmonsia crescens was diagnosed in three of six franklin's ground squirrels (spermophilus franklini) captured in rochester, central alberts, canada in the summer of 1971, and in one of 240 pikas (ochotona princeps) collected in southwestern alberta in 1969. granulomas measuring 0.5 to 1 mm in diameter were found in both lungs. these granulomas contained adiaspores measuring 60 to 400 mum in diameter. the disease was not found in six franklin's ground squirrels c ...1976943581
population differences in benzodiazepine sensitive male scent-induced analgesia in the deer mouse, peromyscus maniculatus.we compared opioid and nonopioid involvement in the mediation of scent-induced analgesia in two populations of deer mice, peromyscus maniculatus; p. m. artemisiae from a mainland region and p. m. angustus from a small marine island. exposure to bedding taken from the soiled home cage of an isolated (dominant aggressive) male resident elicited a significant increase in the nociceptive responses of male deer mice from mixed sex pairs, with the island population of mice displaying significantly gre ...19892544899
muscle fiber size and chronic exposure to hypoxia.sarcomere length is practically never considered when fiber size and dependent variables are compared between muscles or experimental conditions. because of the direct dependence of fiber cross-sectional area on muscle shortening, it is imperative to normalize measurements of fiber size, and related variables (e.g. capillary number/mm2 of fiber) to sarcomere length. we examined the relationship between fiber cross-sectional area and sarcomere length in muscles of animals chronically exposed to h ...19892782154
annual cyclicity of gall stone prevalence in deer mice (peromyscus maniculatus gambelii).the prevalence of gall stones (100% cholesterol) in a deer mouse (peromyscus maniculatus) population located in siskiyou county, california (usa) was studied on a monthly basis from february 1985 through january 1988. during each year we documented a pronounced annual cyclicity with peak prevalence (31 to 53%) during the winter and low prevalence (2 to 3%) during late summer. gall stone prevalence was not related to sex or age of the animal. the earliest onset of gall stone production and the ma ...19892810546
male scent-induced analgesia in the deer mouse, peromyscus maniculatus: involvement of benzodiazepine systems.exposure to bedding taken from the soiled home cage of an isolated male resident elicited a significant increase in the nociceptive responses of male deer mice, peromyscus maniculatus artemisiae, from mixed sex pairs. the analgesia induced by exposure to the male scent was insensitive to the opiate antagonist, naloxone, and was blocked by either pre- or post-olfactory exposure injections of the benzodiazepine antagonist, ro 15-1788, or agonist, diazepam. this non-opioid analgesia was of brief du ...19882835786
the effect of unsaturated and saturated dietary lipids on the pattern of daily torpor and the fatty acid composition of tissues and membranes of the deer mouse peromyscus maniculatus.dietary lipids strongly influence the pattern of torpor and the body lipid composition of mammalian hibernators. the object of the present study was to investigate whether these diet-induced physiological and biochemical changes also occur in species that show shallow, daily torpor. deer mice, peromyscus maniculatus, were fed with rodent chow (control diet) or rodent chow with either 10% sunflower seed oil (unsaturated diet) or 10% sheep fat (saturated diet). animals on the unsaturated diet show ...19911783690
splenomegaly and reticulocytosis caused by babesia microti infections in natural populations of the montane vole, microtus montanus.a survey for babesia microti in rodents was conducted at six sites within grand teton national park, wyoming. blood and spleen smears, hematocrits, and reticulocyte counts were made on all of the animals to evaluate parameters for the diagnosis of babesiosis. ticks were removed for identification. of 257 microtus montanus, 103 were infected with b. microti. in addition, five of 12 microtus pennsylvanicus and one of three arvicola richardsoni were parasitized by b. microti. peromyscus maniculatus ...19911818201
warble development by the rodent bot cuterebra fontinella (diptera: cuterebridae) in the deer mouse.warbles induced by the rodent bot fly larvae, cuterebra fontinella, developed over a period of 3.5-4 weeks in the deer mouse peromyscus maniculatus. warble location, structure and dynamics were examined. clustering of warbles occurred primarily within the inguinal region of the deer mouse with a significant number favoring the area between the anus and genital organ. no differences in warble production were found in hosts of either sex. on two occasions, a warble was encountered forming directly ...19911882496
ontogeny of striking, prey-handling and envenomation behavior of prairie rattlesnakes (crotalus v. viridis).the ontogeny of striking, prey-handling and envenomation behavior was studied in the prairie rattlesnake (crotalus v. viridis). snakes of three size classes (small, medium, large) were allowed to strike and envenomate deer mice (peromyscus maniculatus) of corresponding size. the mass of venom expended in a single strike, assayed by enzyme-linked immunosorbent assay (elisa) of whole-mouse homogenates, increased exponentially with length of the snake. small snakes embedded their fangs in prey for ...19911926185
morphological analysis of hair in the hr-2 mutant deer mouse (peromyscus maniculatus).skin from 36 hairless deer mice (peromyscus maniculatus) homozygous for the recessive hr-2 mutation were analyzed for structural defects in hair and hair loss. comparison of mutant to wild-type hairs demonstrated characteristic abnormalities in cellular organization, hair shape, length, and fragility. matings between mutants homozygous for the hr-2 gene and for a second mutation producing hairlessness in deer mice, hr-1, showed that these two genes were nonallelic. structural abnormalities in ha ...19911940285
lyme disease in california: interrelationship of ixodid ticks (acari), rodents, and borrelia burgdorferi.the association of immature ixodid ticks, several species of rodents, and the lyme disease spirochete, borrelia burgdorferi johnson, schmid, hyde, steigerwalt & brenner, was studied in two habitats in northern california in spring and summer 1985 and year-round in 1986. a total of 428 rodents were collected from ecotonal chaparral and a woodland-grass-rock outcrop; the former habitat yielded six species, the latter three species. the deer mouse, peromyscus maniculatus (wagner), and the piñon mou ...19911941942
coat color genetics of peromyscus. i. ashiness, an age-dependent coat color mutation in the deer mouse.ashy deer mice (peromyscus maniculatus) were first discovered about 1960 in a wild population from oregon. although indistinguishable from the wild type at weaning, ashy deer mice become progressively grayer with subsequent molts. the trait is inherited as an autosomal recessive and the symbol ahy is assigned for the locus. the trait is distinctly manifest by 6 months of age, at which time homozygotes have white hairs on the muzzle and at the base of the tail. the amount of white gradually incre ...19902177072
serologic evidence of yersinia pestis infection in small mammals and bears from a temperate rainforest of north coastal california.from 1983 to 1985, 463 serum samples from 11 species of mammals in redwood national park (rnp) (california, usa) were evaluated for antibodies to yersinia pestis by the passive hemagglutination method. yersinia pestis antibodies occurred in serum samples from 25 (36%) of 69 black bears (ursus americanus), one (50%) of two raccoons (procyon lotor), five (3%) of 170 dusky-footed woodrats (neotoma fuscipes), and one (less than 1%) of 118 deer mice (peromyscus maniculatus). two hundred seventy-three ...19892915403
dehydrogenase-dependent ethanol metabolism in deer mice (peromyscus maniculatus) lacking cytosolic alcohol dehydrogenase. reversibility and isotope effects in vivo and in subcellular fractions.elimination of [2h]ethanol in vivo as studied by gas chromatography/mass spectrometry occurred at about half the rate in deer mice reported to lack alcohol dehydrogenase (adh-) compared with adh+ deer mice and exhibited kinetic isotope effects on vmax and km (d(v/k] of 2.2 +/- 0.1 and 3.2 +/- 0.8 in the two strains, respectively. to an equal extent in both strains, ethanol elimination was accompanied by an ethanol-acetaldehyde exchange with an intermolecular transfer of hydrogen atoms, indicatin ...19892925622
role of alcohol dehydrogenase in the swift increase in alcohol metabolism (siam). studies with deer mice deficient in alcohol dehydrogenase.previous studies have shown that rates of ethanol metabolism increase markedly 2-4 hr after the administration of ethanol in rats and in four inbred strains of mice. this phenomenon, called the swift increase in alcohol metabolism (siam), also exists in humans. to determine whether alcohol dehydrogenase (adh) is necessary for the siam response, we compared ethanol metabolism in two strains of the deer mouse, peromyscus maniculatus. one strain lacks alcohol dehydrogenase (adh-negative), whereas t ...19852932115
comparative anatomy of the retino-hypothalamic tract in photoperiodic and non-photoperiodic rodents.this study examined whether the nearly symmetrical input from each eye to each suprachiasmatic nucleus previously reported in syrian hamsters (mesocricetus auratus) is a universal feature of retino-hypothalamic projections in photoperiodic rodents. intraocular injections of horseradish peroxidase (hrp) were used to trace the retino-hypothalamic tract in three species of photoperiodic rodents, turkish hamster (mesocricetus brandti), deer mouse (peromyscus maniculatus bairdi) and white-footed mous ...19862430681
serological survey of prospect hill virus infection in indigenous wild rodents in the usa.we found serological evidence of infection with prospect hill virus, a hantaan-like virus isolated from meadow voles (microtus pennsylvanicus), in microtine and cricetid rodents trapped in maryland, west virginia, minnesota and california, usa. fluorescent antibodies were detected in sera from m. pennsylvanicus (74/277), m. californicus (39/185), clethrionomys gapperi (5/51), peromyscus maniculatus (4/22) and p. truei (1/11). sera from seropositive p. maniculatus contained neutralizing antibodie ...19872895510
eimeria species (apicomplexa: eimeriidae) infecting peromyscus rodents in the southwestern united states and northern mexico with description of a new species.of 198 deermice (peromyscus spp) collected from various localities in the southwestern united states and northern mexico, 106 (54%) had eimerian oocysts in their feces when examined. these included 50 of 106 (47%) peromyscus truei, 34 of 54 (63%) peromyscus maniculatus, 4 of 17 (24%) peromyscus leucopus, and 18 of 21 (86%) peromyscus eremicus. the following eimeria were identified from infected mice: eimeria arizonensis and eimeria langebarteli from p. truei; e. arizonensis, eimeria peromysci, a ...19854057004
effects of laryngeal denervation on ultrasound production and male sexual behavior in rodents.adult male house mice (mus musculus) and deer mice (peromyscus maniculatus bairdi) were used to investigate the effects of partial denervation of the larynx on ultrasound production. in addition the masculine sexual behavior of vocalizing and muted males was assessed on tests with receptive females. for both species, unilateral transections of the inferior laryngeal nerve (iln) significantly reduced the proportion of males that emitted ultrasonic vocalizations. however, the inability to vocalize ...19854059379
pathogenesis of trypanosoma equiperdum in deer mice (peromyscus maniculatus). 19744210290
in vitro fertilization of two species of deer mouse eggs by homologous or heterologous sperm and penetration of laboratory mouse eggs by deer mouse sperm.newly ovulated eggs from immature deer mice (peromyscus maniculatus and p. polionotus) and mature laboratory mice (mus musculus) treated with pmsg and hcg were inseminated in vitro with spermatozoa recovered from the cauda epididymidis of mature males. the time required for capacitation of deer mouse sperm in culture was estimated to be about two to five hours based on the dispersal of sperm agglutination and increase of sperm motility. the rate of sperm penetration through the zona pellucida of ...1979572865
modoc-like virus isolated from wild deer mice (peromyscus maniculatus) in alberta.small mammals were trapped in northeastern alberta, canada during 1976. blood samples from these animals were tested for virus by inoculation of suckling mice. blood clots from two deer mice yielded isolates of the same virus. the virus was related antigenically to a number of flaviviruses which have been isolated from mammals in central america and north america and was related most closely to modoc virus. physical, chemical, and biological properties of the virus were similar also to those of ...19852987550
differential opiate influences on food hoarding and intake in the deer mouse, peromyscus maniculatus.the feeding behavior of the deer mouse, peromyscus maniculatus, includes food hoarding as well as ingestion. in this animal the mu opiate agonist, morphine, and the kappa opiate agonist, u-50, 488h, selectively stimulate food hoarding and ingestion, respectively. this suggests that mu and kappa opiate systems may differentially mediate primary components of natural feeding behavior.19852999543
serological and virological evidence of a hantaan virus-related enzootic in the united states.the first isolation of a hantaan-related virus from a feral rat in the united states was made from a rattus norvegicus caught in new orleans. the strain, designated tchoupitoulas virus, is antigenically related to, but distinct from, the prototype strain 76-118 of hantaan virus and is the first hantaan-like virus isolated from the pancreas of a naturally infected animal. serosurveys of wild rodents from urban and rural areas in the united states indicated that hantaan-related viruses infected ur ...19852861241
metabolic and biochemical aspects of heat acclimation in the deer mouse. peromyscus maniculatus sonoriensis. 19763322
7s-gamma-1, 7s-gamma-2 and igm immunoglobulins in the deer mouse (peromyscus maniculatus). 19694981681
immunosuppression in experimental trypanosomiasis: effects of trypanosoma equiperdum on the pathogenesis of influenza virus infection in deer mice (peromyscus maniculatus).the effects of trypanosoma equiperdum infections on the immunological and pathological responses of deer mice (peromyscus maniculatus) to influenza virus exposure were investigated. mice carrying a 5 week trypanosome infection along with an age- and sex-matched trypanosome-free control group were simultaneously exposed to influenza ao (wsn) virus. t. equiperdum infection significantly (p less than 0.01) converted a sub-lethal virus attack into a fatal pneumonic process in a small proportion of a ...19853002002
experimental infection and horizontal transmission of modoc virus in deer mice (peromyscus maniculatus).deer mice (peromyscus maniculatus) were inoculated with a sublethal dose of a field strain of modoc virus to determine patterns of viral persistence, shedding, and transmission. blood, serum, urine, fecal, and oral swab samples were collected at selected intervals until 63 days postinoculation (pi) after which lung, liver, spleen, kidney, and salivary glands were explanted. viral assays were conducted by intracranial inoculations of suckling mice and antibody titers were determined by the micro- ...19873035240
influence of photoperiod, ambient temperature and melatonin on testosterone synthesis and release during reproductive maturation in male deer mice.four experiments were designed to investigate the influence of photoperiod and other environmental factors on androgen production and reproductive maturation in deer mice. male prairie deer mice (peromyscus maniculatus), born in a light/dark cycle of 6l:18d, either remained in this short photoperiod or were switched to a long day regimen of 16l:8d at weaning. in a cross-sectional experiment, the deer mice were killed between 3 and 8 weeks of age for measurement of serum testosterone concentratio ...19883346178
observations on the breeding success of the deer mouse, peromyscus maniculatus nubiterrae. 19734705258
identification of p-450alc in microsomes from alcohol dehydrogenase-deficient deermice: contribution to ethanol elimination in vivo.isozyme 3a of rabbit hepatic cytochrome p-450, also termed p-450alc, was previously isolated and characterized and was shown to be induced 3- to 5-fold by exposure to ethanol. in the present study, antibody against rabbit p-450alc was used to identify a homologous protein in alcohol dehydrogenase-negative (adh-) and -positive (adh+) deermice, peromyscus maniculatus. the antibody reacts with a single protein having an apparent molecular weight of 52,000 on immunoblots of hepatic microsomes from u ...19883395117
chromosome polymorphism in interbred subspecies of peromyscus maniculatus (deer mouse). 19715110191
susceptibility of the gray wolf (canis lupus) to infection with the lyme disease agent, borrelia burgdorferi.four juvenile gray wolves (canis lupus) were inoculated with live borrelia burgdorferi. one received an intravenous inoculum, a second was inoculated subcutaneously, and two more were fed peromyscus maniculatus sucklings which had earlier been inoculated with b. burgdorferi. the intravenously inoculated wolf developed a generalized lymphadenopathy and a persistent serum antibody titer to the spirochete which peaked at 1:512. borrelia burgdorferi was visualized in liver sections of this wolf usin ...19883411709
food hoarding and ingestion in the deer mouse, peromyscus maniculatus: selective responses to mu and kappa opiate agonists.the feeding behavior of the deer mouse, peromyscus maniculatus, includes food hoarding as well as ingestion. administration of the prototypical mu opiate agonist, morphine sulfate, 1-20 mg/kg, produced over three hours a significant dose-dependent stimulation of hoarding by free feeding deer mice. the specific kappa opiate agonist, u-50,488h, 0.10-10 mg/kg, markedly increased ingestion without having any augmentatory effects on hoarding. the mixed mu and kappa opiate agonist, ketocyclazocine hyd ...19863022306
accelerated wound repair in old deer mice (peromyscus maniculatus) and white-footed mice (peromyscus leucopus).the closure of bilateral full thickness cutaneous wounds, made over the back with a sharp paper punch, was measured and assessed histologically in outbred deer mice (peromyscus maniculatus) and white-footed mice (peromyscus leucopus). in contrast to inbred c57bl/6j laboratory mice (mus musculus), in which the rate of wound repair was more rapid in young than in mature or aged mice (cohen et al., 1987), wound repair in peromyscus was most rapid in aged animals. aged peromyscus (45 to 70 months) a ...19873571866
platinum coat color locus in the deer mouse.platinum coat color in the deer mouse, peromyscus maniculatus, is an autosomal recessive trait marking a locus, pt, distinct from silver (si), albino (c), blonde (bl), brown (b), and agouti (a). platinum deer mice are conspicuously pale, with light ears and tail stripe. the pewter trait is allelic with and phenotypically identical to platinum, and represents an independent recurrence of this mutant. the rate of recoveries of coat color mutations from wild deer mice is consistent with available d ...19873611714
papillomas (warts) in hairless mice. mus musculus and peromyscus maniculatus gambeli. 19705515192
hemoglobin polymorphism in the deer mouse, peromyscus maniculatus. 19685717667
modoc viral infections in the deer mouse peromyscus maniculatus.the pathogenesis of modoc virus and its mechanism of transmission were investigated in peromyscus maniculatus gambeli (deer mouse) as a model to understand the natural history of this virus. animals were readily infected by the intranasal or subcutaneous route of inoculation. virus could be detected by direct isolation techniques in many organs and body fluids during the first 7 to 9 days after intranasal inoculation. increases in viral titers were detectable first in lungs and then the spleen, ...19744215763
the molecular organization of the beta-globin complex of the deer mouse, peromyscus maniculatus.recombinant dna clones have been isolated that contain 80 kb of the beta-globin complex from the deer mouse, peromyscus maniculatus. comparisons of this complex with that from the laboratory mouse, mus domesticus (with an order 5'-hbby, hbb-bho, hbb-bhl, hbb-bh2, hbb-bh3, hbb-bl, hbb-b2 3') highlight organizational trends in the beta-globin complex since the two species diverged. unlike other mammals studied thus far, the deer mouse possesses three adult genes. partial sequence analysis indicate ...19873447002
oral infection of peromyscus maniculatus with borrelia burgdorferi and subsequent transmission by ixodes dammini.we determined if deer mice (peromyscus maniculatus) could be infected by borrelia burgdorferi and develop sufficient spirochetemia to infect larval ixodes dammini. ten p. maniculatus were infected orally with 0.05 ml phosphate buffered saline containing approximately 400 b. burgdorferi. on days 21 or 28 after infection (ai) larval i. dammini were fed on the deer mice. each of the p. maniculatus developed antibodies (up to 7 log2) to b. burgdorferi and b. burgdorferi was isolated from the blood o ...19873826500
heat loss regulation: role of appendages and torso in the deer mouse and the white rabbit.thermal conductance was subdivided into the component conductances of the appendages and torso using a heat transfer analysis for the deer mouse, peromyscus maniculatus, and the white rabbit, oryctolagus cuniculus. our analysis was based on laboratory measurements of skin temperature and respiratory gas exchange made between air temperatures of 8 and 34 degrees c for the deer mouse, and from published data for the white rabbit. two series conductances to heat transfer for each appendage and tors ...19853837023
evaporative water loss: thermoregulatory requirements and measurements in the deer mouse and white rabbit.using a physical model of the capacity for non-evaporative heat loss and measurements of metabolic heat production, i evaluated the evaporative requirements for thermoregulation in the deer mouse, peromyscus maniculatus, and the white rabbit, oryctolagus cuniculus. the physical limit to non-evaporative heat loss was calculated from the heat transfer properties of the two animals and expressed as a maximum thermal conductance (cmax). two physiologically-based thermal conductances were derived fro ...19853837024
chronic and acute trypanosomiasis in mice: a study by in vitro cloning of lymphohaematopoietic progenitors.a semi-solid culture system was used to study the effects of trypanosome infection in two species of mice on the propagation of progenitor cells from the bone marrow and spleen. the deer mouse (peromyscus maniculatus) survived infection with trypanosoma (t.) equiperdum for more than 15 days. during the first 10 days there was inhibition of development of granulocyte-monocyte colonies from progenitor cells in the bone marrow. b-lymphocyte progenitors in the spleen showed increased activity, produ ...19853873680
failure of 2-deoxy-d-glucose to stimulate feeding in deermice.deermice (peromyscus maniculatus) did not increase their food intake above baseline following treatment with 2-deoxy-d-glucose (2dg, 500 or 1000 mg/kg). they did eat more following food deprivation or treatment with insulin at a high dose (100 u/kg). house mice (mus musculus) showed hyperphagia to 2dg, low dose of insulin (5 u/kg) and deprivation.19853898162
neurons in the suprachiasmatic area are labelled after intravenous injections of horseradish peroxidase.intravenous injections of horseradish peroxidase (hrp) produced labelled neurons in the suprachiasmatic area of house mice (mus musculus), deer mice (peromyscus maniculatus bairdi), and white-footed mice (peromyscus leucopus). in the two species of peromyscus, a significant proportion of the labelled cells was found within the suprachiasmatic nucleus (scn). these results suggest that when hrp is injected in the eyes to trace retinal inputs to the hypothalamus, some of the reaction product seen i ...19873622673
disruption of ejaculates by male copulation in deer mice (peromyscus maniculatus).six experiments were conducted to analyze possible disruption of sperm transport occurring when one male deer mouse copulates soon after another male ejaculates. when a second male mated soon after the first, females had significantly fewer uterine sperm 1 hr later than when a delay of 7 or 15 min was imposed between males. however, it was impossible to detect any effect of such disruption on pregnancy initiation. similarly, artificial stimulation soon after an ejaculation was ineffective in dis ...19873685153
experimental infection with western equine encephalomyelitis virus in wild rodents indigenous to kern county, california.six species of rodents from kern county, california, were inoculated subcutaneously with western equine encephalomyelitis (wee) virus to determine their susceptibility to infection and their potential as natural hosts. ammospermophilus nelsoni, citellus beecheyi, dipodomys heermanni, dipodomys nitratoides, peromyscus maniculatus, and sciurus griseus were readily infected. infection was usually fatal in dipodomys species, c. beecheyi, and s. griseus, but was clinically inapparent in other species ...19744426699
the mechanism of autosomal synapsis and the substaging of zygonema and pachynema from deer mouse spermatocytes.surface-spread and silver-stained spermatocytes of peromyscus maniculatus and p. sitkensis were analyzed in order to develop criteria for the recognition of meiotic substages from early zygonema through early diplonema. the continuous sequence of changes in the morphology of the autosomal axes (lateral elements) of the synaptonemal complexes (sc), sex chromosome axes, and nucleoli enabled the recognition of three substages of zygonema and five of pachynema. the proposed system of subdivision is ...19863948599
photoperiodic time measurement in the male deer mouse, peromyscus maniculatus.weanling male deer mice, peromyscus maniculatus, were exposed for three weeks either to light-dark (ld) cycles with periods (t=l+d) ranging from t=23 (1l:22d) to t=25.16 (1l:24.16d) or to 24-h ld cycles with photoperiods ranging from 1 (1l:23d) to 19 (19l:5d) h. both the circadian locomotor activity rhythms and the response of the reproductive system to these ld cycles were assessed. the results demonstrate that the photoperiodic effectiveness of light depends on the phase of the light relative ...19854005352
the ecology of the deer mouse, peromyscus maniculatus, in a coastal coniferous forest. iii. stomach-weight variation. 19744434276
odor preferences of female peromyscus maniculatus bairdi for male mouse odors of p. m. bairdi and p. leucopus noveboracensis as a function of estrous state. 19724673475
yersinia philomiragia sp. n., a new member of the pasteurella group of bacteria, naturally pathogenic for the muskrat (ondatra zibethica).a bacterium experimentally pathogenic for muskrats (ondatra zibethica), white mice, mountain voles (microtus montanus), and deer mice (peromyscus maniculatus) was isolated from the tissues of a sick muskrat captured on the bear river migratory bird refuge (brigham city, utah) and from four surface water samples collected within 15 miles of that point. in culture, the cells are chiefly coccoid, but in the tissues of muskrats and voles they resemble the bizarre forms of yersinia pestis, except for ...19695361214
reactions of deer mice (peromyscus maniculatus) and white-footed mice (peromyscus leucopus) to homospecific and heterospecific urine odors. 19734737448
studies on sylvatic echinococcosis. iv. ecology of echinococcus multilocularis in the intermediate host, peromyscus maniculatus, in north dakota, 1965-1972. 19744847041
effects of olfactory experience on aggression in mus musculus and peromyscus maniculatus. 19725064952
echinococcus multilocularis in peromyscus maniculatus and vulpes vulpes from minnesota. 19685757663
studies on sylvatic echinococcosis. 1. ground beetle transmission of echinococcus multilocularis leuckart, 1863, to deer mice, peromyscus maniculatus (wagner). 19685757728
chromosome polymorphism in deer mouse siblings (peromyscus maniculatus). 19705439624
the chromosomes of peromyscus maniculatus hollesteri (deer mouse). 19675594480
hexose-6-phosphate dehydrogenase found in human liver.starch-gel electrophoresis of extracts of human liver revealed the presence of a new hexose-6-phosphate dehydrogenase that was slower-moving at ph 8.6 than the sex-linked glucose-6-phosphate dehydrogenase. when the gel plate was stained, galactose-6-phos phate being used as a substrate, this enzyme band stained intensely, but the sex-linked glucose-6-phosphate dehydro genase failed to stain. this new human enzyme may well be homologous with the autosomally inherited glucose-6-phosphate dehydroge ...19665917551
topography and vascularization of brown fat in a small nonhibernator (deer mouse, peromyscus maniculatus). 19695378703
mice: individual recognition by olfactory cues.mice discriminated between two male mice of the same inbred strain on the basis of olfactory cues. mice could also discriminate by olfactory cues between two different species, c3h mus musculus and peromyscus maniculatus, and between males and females.19676057298
cestode in north dakota: echinococcus in field mice.field mice (microtus pennsylvanicus and peromyscus maniculatus) are naturally infected with echinococcus multilocularis. thus, the sylvatic cycle (fox to field mice to fox) has been established in north dakota. this cestode is expected to extend its range to other agricultural regions of the continental united states where similar conditions favorable for the completion of its life cycle exist.19655891703
linkage relationships among eleven biochemical loci in peromyscus.interspecific f1 hybrids of peromyscus maniculatus (deermice) and p. polionotus (oldfield mice) were backcrossed to p. maniculatus. backcross progeny were electrophoretically typed for 11 variant protein markers: albumin, transferrin, leucine aminopeptidase, amylase, 6-phosphogluconate dehydrogenase, nucleoside phosphorylase, dipeptidase, tripeptidase, glutamate oxaloacetate transaminase, alcohol dehydrogenase, and sorbitol dehydrogenase. genetic variation for each protein was attributed to a si ...19836200103
axonal dystrophy in a deer mouse (peromyscus maniculatus) with an inherited ataxia and tremor. 19695787431
autosomal polymorphism due to pericentric inversions in the deer mouse (peromyscus maniculatus), and some evidence of somatic segregation. 19665932751
effects of experimental infection of the deer mouse (peromyscus maniculatus) with mouse hepatitis virus.three deer mice (peromyscus maniculatus) given 10(4) tcid50 of mouse hepatitis virus -s intranasally all had significant serum neutralization titers to mouse hepatitis virus -s 3 weeks later. ten other deer mice were given 10(3) tcid50 of mouse hepatitis virus -3 intranasally and placed with sentinel laboratory mice (cf1, c3h/rv, and nu/nu) and uninoculated deer mice. one inoculated deer mouse died, but mouse hepatitis virus was not isolated. no other inoculated or uninoculated animals exhibited ...19826285078
medroxyprogesterone, immunosuppression, and conceptus size in peromyscus.effects of exogenous medroxyprogesterone acetate (mpa) on skin transplant retention and conceptus size were studied in the deer mouse, peromyscus maniculatus, and the oldfield mouse peromyscus polionotus. daily injections of 2 mg mpa significantly prolonged survival of allografts in p. maniculatus and transspecific grafts between p. maniculatus and p. polionotus. allografts were retained significantly longer than transspecific grafts (17.2 vs 12.4 days) on mpa-treated p. maniculatus. near-term f ...19836345716
evidence for heterosynaptic pairing of the inverted segment in pericentric inversion heterozygotes of the deer mouse (peromyscus maniculatus).silver-stained pachytene cells of male deer mice, peromyscus maniculatus, which were heterozygous for a naturally occurring pericentric inversion of chromosome 6, were analyzed by light microscopy. the presence of the terminally positioned inversion, involving approximately 30% of the length of chromosome 6, was detected by g-banding. within the inversion, c-band-positive heterochromatin was restricted to the centromeric region. silver-staining of spermatocytes revealed the synaptonemal complexe ...19846467983
kinetics of cytoplasmic aspartate aminotransferase from three genotypes of the deer mouse (peromyscus maniculatus).three genotypic forms of the cytoplasmic enzyme, aspartate aminotransferase from the deer mouse (peromyscus maniculatus) were each analyzed kinetically after partial purification. kmapp and vmax for aspartate decreased in value as temperature changed from 37.9 to 15 degrees c for all three forms. for the aa genotype, the binding enthalpies were highest at 37.9 degrees c and lowest at 25 degrees c, while for the a'a' form, they were lowest at 37.9 degrees and highest at 25 degrees c. results for ...19846478801
adrenal weight in prairie deer mice (peromyscus maniculatus bairdii) and white-footed mice (peromyscus leucopus noveboracensis). 19676070648
experimental colorado tick fever virus infection in colorado mammals.one hundred and twenty-four small mammals of six species were inoculated with three strains of colorado tick fever (ctf) virus to define viremia and neutralizing (n) antibody responses. adult eutamias minimus and eutamias embrinus, and juvenile peromyscus maniculatus and spermophilus lateralis, were highly susceptible to development of viremic infection. adult s. lateralis and p. maniculatus were moderately susceptible (greater than or equal to 50% viremic). five sylvilagus nuttalli did not beco ...19816259958
the ecology of colorado tick fever in rocky mountain national park in 1974. ii. infection in small mammals.field studies of colorado tick fever (ctf) in small mammals in rocky mountain national park (rmnp) in 1974 established that eutamias minimus and spermophilus lateralis were the most important hosts for ctf virus and were the source of virus for immature stages of the tick vector, dermacentor andersoni. other species (peromyscus maniculatus, spermophilus richardsonii, eutamias umbrinus) are secondary hosts. the intensity of viral activity in rodents varied greatly from locality to locality. highe ...19816263122
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