| experimental design for the surgical relocation of the ovary into the vaginal fornix. | after translocation into the vaginal vault while attached to a pedicle consisting of the infundibulo-pelvic ligament, the ovary was found to maintain its function in laboratory primates. in the majority of the baboons the ovulatory pattern returned within a few weeks after the surgical procedure. the only significant complication was a transitory, and self-limited, infection which was evident on inspection and on the biopsy specimens, but caused no clinical symptoms. by comparing the surgical ou ... | 1979 | 45099 |
| expression of baboon endogenous virus in exogenously infected baboon cells. | strains of low-passage, fetal diploid, baboon (papio cynocephalus) fibroblasts were susceptible to exogenous infection with three independent isolates of baboon endogenous virus, as measured by an immunofluorescence assay specific for viral p28. infectivity of the m7 strain of baboon endogenous virus for baboon cells of fetal skin muscle origin was equivalent to that for human and dog cells in that similar, linear, single-hit titration patterns were obtained. the assay for supernatant rna-depend ... | 1979 | 90162 |
| the nature of a primary feeding habit in different age-sex classes of yellow baboons (papio cynocephalus). | two feeding habits of 30 baboons selected equally from five age-sex classes were studied at mikumi national park, tanzania. the finding, gathering, and preparing of sedge corms and of seeds of tamarind fruit were described in detail. adults obtained these foods faster than younger animals, although even small juveniles and weaned infants were efficient in gathering and preparing them. while gathering sedges or tamarinds, adult males sat in one place longer than others and obtained more food per ... | 1978 | 101429 |
| decreased renal blood flow in the baboon during mild dynamic leg exercise. | twelve chair-restrained baboons (papio cynocephalus) were conditioned with operant techniques and a food reward to perform 4 min of dynamic leg exercise. during the last minute of exercise, blood flow through the left renal artery, measured by an electromagnetic flow transducer, was decreased 19 +/- 2% sem with respect to the minute of rest preceding the exercise. this response occurred within 1.5 min, was maintained throughout the exercise, and recovered to control within 2 min. mean arterial b ... | 1979 | 107812 |
| the isolation of herpesvirus from trigeminal ganglia of normal baboons (papio cynocephalus). | a herpesvirus was isolated from the trigeminal ganglia of three of six normal baboons (papio cynocephalus). this virus possessed the virologic characteristics of sa8, a herpesvirus known to be indigenous to the baboon. | 1978 | 108465 |
| the baboon as a primate model for the study of endometrium. | a series of transcervical uterine biopsy specimens were obtained at various stages of the menstrual cycle from a colony of 11 normally cycling female baboons, papio anubis and papio cynocephalus. morphologically, baboon endometrium appeared to be similar to human endometrium. alkaline phosphatase activity was maximal throughout the preovulatory phase and during the late postovulatory period. during the preovulatory phase acid phosphatase was not demonstrable but increased after ovulation to reac ... | 1979 | 110149 |
| african baboon (papio cynocephalus) infected with three strains of schistosoma mansoni. | | 1979 | 113522 |
| a longitudinal study of facial growth in papio cynocephalus after resection of the cartilagenous nasal septum. | the present study evaluates in papio cynocephalus the effectiveness of varying the amount of nasal septum resected and the age at surgery in an attempt to develop a technique which may have clinical value for the human condition. the analysis of interdental dimensions by graphical techniques demonstrates that a critical age exists at which total septum resection leads to maximum growth arrest of the premaxilla. comparisons of linear regression curves for operated and control animals confirm thes ... | 1979 | 113543 |
| fetal infection of the baboon (papio cynocephalus) with lymphocytic choriomeningitis virus. | recent observations of lcm-induced fetal damage in humans suggested attempts to develop an animal model for studies on viral congenital malformations. we report herein viral studies on three pregnant baboons (papio cynocephalus) inoculated subcutaneously with lcm virus strain we3. the first animal, inoculated in the 9th week of pregnancy, aborted 9 days after a high virus dose. inoculation of the second baboon during a later stage (23rd week) of pregnancy with a moderate virus dose, resulted in ... | 1979 | 116625 |
| the chemotactic, phagocytic, and microbial killing abilities of primate polymorphonuclear leukocytes (pml). | functions of polymorphonuclear leukocytes including chemotaxis, phagocytosis, and microbial killing were investigated in baboons (papio cynocephalus), cebus monkeys (cebus apella), and marmosets (saguinus oedipus). cells from a group of normal adult human volunteers were also studied for comparison. polymorphonuclear leukocytes from the three nonhuman primate species were comparable to each other and to humans in chemotactic activity using endotoxin activated serum. in addition, the ability of b ... | 1979 | 121031 |
| steriod changes during the menstrual cycle of the baboon (papio cynocephalus) and human. | | 1978 | 149569 |
| connective tissue proteins of the baboon lung: concentration, content and synthesis of collagen in the normal lung. | lung connective tissue proteins have been assayed in 12 normal juvenile baboons (papio cynocephalus). the collagen concentration (26.8 +/- 5.1 microgram hydroxyproline per mg dry weight) is comparable to values reported for adult human lung, while the rate of collagen synthesis (0.242 +/- 0.082 nmoles hydroxyproline per mg dna per hour) is approximately half that of human lung. proteins other than collagen are synthesized at approximately equal rates in human and baboon lung. elastin concentrati ... | 1978 | 150961 |
| isolation of foamy viruses from baboon (papio cynocephalus) tissues. | fourty per cent of baboon kidney cell cultures were found to contain foamy virus contaminants regardless of sex of the animal, source or time of year. the older the animal, however, the higher the incidence. fifty percent of placentas examined contained foamy virus, with first and second trimester specimens more likely to be positive. foamy virus isolates from baboon lymphocytes were also more frequent as the age of the animal increased. freezing and thawing these lymphocytes prevented foamy vir ... | 1975 | 168767 |
| clinical, virological, and pathological features of herpesvirus sa8 infection in conventional and gnotobiotic infant baboons (papio cynocephalus). | the pathogenicity of a strain of simian herpesvirus sa8 in one month old conventional and gnotobiotic baboons was investigated. intratracheal inoculation resulted in a mortality rate of 1/5 in the conventional and 1/4 in the gnotobiotic group. disease became apparent after 3 days and was characterized by respiratory distress, reduced formula intake, weight loss and fever in both groups. isolation of herpesvirus from the respiratory tract, lymphoid organs, kidneys, adrenals, and cns was more freq ... | 1976 | 179497 |
| isolation and biological properties of endogenous baboon (papio cynocephalus) type c viruses. | | 1975 | 183663 |
| poxvirus infection of the baboon (papio cynocephalus). | ten serial passages of monkeypox (mpv), vaccinia, variola, and chimpanzeepox (chimp-9) viruses were performed in baboons (papio cynocephalus) via skin scarification. comparisons of clinical and virological results indicate that mpv and vaccinia are very closely related and that variola and chimp-9 viruses are identical. these findings suggest that infections of simians with chimp-9 virus resulted from contact with variola virus, the source of which is still unknown. on the other hand, mpv in mon ... | 1976 | 191209 |
| viral infections of the captive kenya baboon (papio cynocephalus): a five-year epidemiologic study of an outdoor colony. | rectal swabs, throat swabs, fecal samples, tissues, and sera were collected from 334 adult and infant kenya baboons (papio cynocephalus) in captivity at this institution over a 5-year period. a total of 4,893 specimens were collected, resulting in the isolation of 582 viral isolates (11.9%). the month of november yielded the lowest isolation rate, while the month of january produced the highest rate. the most commonly isolated viruses in adults and infants were sv6 and sv23, followed by n125, sv ... | 1977 | 195135 |
| nonhuman primates: laboratory animals of choice for neurophysiologic studies of sleep. | a systematic study was made of several nonhuman primates to learn more about their relative usefulness for studies of sleep. species studied included the guinea baboon (papio papio), kenya or yellow baboon (p cynocephalus), olive baboon (p anubis), sacred baboon (p hamadryas), vervet monkey (cercopithecus aethiops), rhesus monkey (macaca mulatta), bonnet monkey (m radiata), crab-eating monkey (m fascicularis), patas monkey (erythrocebus patas), chimpanzee (pan troglodytes), mongoose lemur (lemur ... | 1977 | 201798 |
| isolation and characterization of a new simian foamy virus serotype from lymphocytes of a papio cynocephalus baboon. | a new type of syncytium-forming (foamy) virus was isolated from peripheral lymphocytes of a papio cynocephalus baboon after cocultivation with a rhesus monkey cell line. the isolate was characterized by cytopathogenic effect, host range, electron microscopy, reverse transcriptase activity and physical and chemical properties. seroneutralization tests indicate that the new isolate is antigenically distinct from the other nine known simian foamy virus serotypes. | 1979 | 231658 |
| vaginal transposition of the ovary in primates (papio cynocephalus and macaca arctoides). | experimental data indicate that the time and mechanism of ovulation play a significant role in some cases of infertility and in a broad range of reproductive abnormalities. in order to establish a new experimental model for the study of these phenomena in primates, transposition of the ovary from the pelvis into the vaginal fornix was attempted in 2 species of monkeys: (a) macaca arctoides and (b) papio cynocephalus. particularly in the latter species, ovarian relocation into the anterior and th ... | 1978 | 278593 |
| differential habitat utilizati of four cercopithecidae in a kenyan forest. | the presence of papio cynocephalus, cercopithecus mitis, cercopithecus aethiops and colobus angolensis in a small coastal forest is attributed to their differential habitat utilization. data on diet, space-use patterns and polyspecific associations are given. habitat partitioning is found to be resource-related and is accomplished through differential reliance on resources as well as different means of exploiting overlapping resources. the implications of the data for understanding the relations ... | 1977 | 403113 |
| light and electron microscopical study on sarcocysts from muscles of the rhesus monkey (macaca mulatta), baboon (papio cynocephalus) and tamarin (saguinus(=oedipomidas) oedipus). | sarcocystis cysts from muscles of monkeys (baboon, tamarin and rhesus monkey) were studied by means of light and electron microscopy. the differences in the morphology of the cyst wall and parasites clearly indicate that the three monkey species examined were each parasitized by at least a specific sarcocystis species being not identical with s. nesbitti or s. kortei. the large numbers of cysts found within the muscle fibres point out the important role that have these monkeys as intermediate ho ... | 1977 | 403695 |
| gm and inv studies on baboons, papio cynocephalus: analysis of serum samples from kenya, ethiopia and south africa. | | 1977 | 407802 |
| biologic and antigenic characteristics of epstein-barr virus-related herpesviruses of chimpanzees and baboons. | leukocyte-transforming agents were isolated in baboon leukocytes inoculated with oral excretions from immunosuppressed chimpanzees. the transformed lymphoblasts had b cell surface markers and harbored herpes-type virus particles; 5-10% of the cells contained cytoplasmic antigens reactive with epstein-barr virus (ebv)-antibody-positive chimpanzee, human and baboon sera. these sera also neutralized the transforming activity of the chimpanzee virus. long-term lymphoid cell lines were established fr ... | 1977 | 409690 |
| renal vascular response to heat stress in baboons--role of renin-angiotensin. | to determine if hyperthermia in the baboon caused a reduction of renal blood flow (rbf) similar to that reported in man, we repeatedly exposed six unanesthetized male baboons (papio cynocephalus) to ambient temperatures of 42.5-49.0 degrees c for 55-175 min. internal temperatures rose 1.0-2.0 degrees c. on the average, rbf fell 23.7% per degrees c, renal vascular resistance (rvr) rose 34.0% per degrees c, and mean arterial pressure (map) fell by only 2.9 torr. plasma renin activity (pra), measur ... | 1977 | 409711 |
| the b-vitamin content of baboon (papio cynocephalus) milk. | 1. the b-vitamins in milk from baboons (papio cynocephalus) at various stages of lactation were measured microbiologically. 2. mature milk contained, on average (microgram/ml): thiamin 0.18 riboflavin 0.74, nicotinic acid 3.2, folate 0.03, vitamin b6 0.70 vitamin b12 0.002, pantothenic acid 2.63, biotin 0.0065. 3. colostrum contained much less vitamin b6 and pantothenic acid than mature milk; otherwise, there were only slight changes in composition as lactation progressed. neither these changes, ... | 1977 | 412516 |
| measurement of hemolytic complement and the third component of complement in nonhuman primates. | complement, determined by hemolytic assay, and the third component of complement (c3), determined by radial immunodiffusion assay, were measured in nine nonhuman primate species. the species studied were the titi (callicebus mollach). the sooty mangabey (cercocebus atys), the thick-tailed galago or bushbaby (galago crassicaudatus panganiensis), the crab-eating monkey (macaca fascicularis), the rhesus monkey (macaca mulatta), the bonnet monkey (macaca radiata), the stumptailed macaque (macaca spe ... | 1977 | 414024 |
| the chromosomal location of rdna in selected lower primates. | hybridization in stiu was used to identify the chromosomes that carry rdna in representative lower primates, including the baboons, papio cynocephalus and papio hamadryas; the colobus monkey, colobus polykomos; the tree shrew, tupaia glis; the lemur, lemur fulvis; the saki, pithecia pithecia; the marmoset, saguinus nigricollis, and the spider monkey, ateles geoffroyi. the marker chromosome, common to the cercopithecines studied to date, carries the rdna in the baboons. another marker chromosome ... | 1977 | 414888 |
| radiographic diagnosis of choanal atresia induced prenatally with triamcinolone in the baboon (papio cynocephalus). | choanal atresia was diagnosed radiographically using a water soluble contrast media in 2 of 7 papio cynocephalus exposed to triamcinolone acetonide in utero. in one p. cynocephalus, the atresia was complete and was associated with other orofacial abnormalities. the other animal, previously considered to be normal, had a partial nasal obstruction. the radiographic appearance of the drug-induced defects observed in the baboon closely resemble the descriptions of spontaneously occurring defects in ... | 1977 | 416215 |
| complete sequence of the gamma chain from the fetal hemoglobin of the baboon, papio cynocephalus. | the amino acid sequence of the hemoglobin gamma chain from a baboon, papio cynocephalus, was determined by automated sequencing of the intact chain and six fragments generated by specific clevage reactions. the existence of structural heterogeneity at position 75, where both valyl and isoleucyl residues were found, is suggestive of the presence of nonallelic v gamma- and i gamma-chain genes in this species, and further emphasizes the extent to which the genetic basis of hemoglobin production amo ... | 1979 | 511581 |
| cardiovascular depressant effects of the neomycin-streptomycin group of antibiotics. | cardiovascular depressant effects of the neomycin-streptomycin group of antibiotics (aminoglycoside antibiotics) were examined during pentobarbital anesthesia in cats, dogs, and 4 species of nonhuman primates: owl (aotus trivirgatus), squirrel (saimiri sciureus), and rhesus (macaca mulatta) monkeys, and dog-faced baboons (papio cynocephalus). intravenous administration of kanamycin, streptomycin, gentamicin, or neomycin produced various degrees of hypotension and relative bradycardia in all spec ... | 1975 | 803801 |
| entopolypoides macaci mayer, 1934 in the african baboon (papio cynocephalus l. 1766). | entopolypoides maaci occurs in different populations of papio cynocephalus in kenya, but not in the same host with hepatocystis kochi. parasitemia may be greatly enhanced by splenectomy, but there is little effect on the host in spite of substantial alteration in hemoglobin and rbc counts, and transferability to other primates is erratic. descriptions are presented for differentiation of e. macaci from h. kochi. | 1975 | 804557 |
| a review of 105 necropsies in captive baboons (papio cynocephalus). | in contrast to the findings in newly caught babboons in africa, the leading cause of death in captivity in america was a pneumonia and enteritis complex. bacterial species such as proteus morgani, proteus mirabilis, clostridium sp., pseudomonas paracolon, pathogenic escherichia coli and cocci have been isolated in association with a pneumoenteric syndrome of 35 newborn baboons, including neonates. the majority of these animals died with pulmonary factors such as anoxia and pneumonia. | 1975 | 808667 |
| chlamydial infection of the male baboon urethra. | two adult male baboons (papio cynocephalus) were infected by urethral catheter with a type d strain of chlamydia trachomatis isolated from a male patient with nongonococcal urethritis. chlamydial organisms were shed from the urethra for about 90 days and serum antibody developed. intraurethral re-inoculation of homologous and heterologous (type i) strains of chalmydia, 4 and 11 months later, resulted in relatively shorter periods of infection of less than 15 days. the antibody titres and type-sp ... | 1975 | 811318 |
| the thermoreculatory responses of the galago (galago crassicaudatus), the baboon (papio cynocephalus) and the chimpanzee (pan stayrus) to heat stress. | 1. the thermoregulatory response of the galago, the baboon and the chimpanzee were studied on exposure to dry bulb temperatures of up to 40 degrees c in a temperature controlled room. 2. heat exposure caused an elevation in the respiratory frequency of all three species. the increase in the galago was significantly greater than that in the baboon and the chimpanzee. 3. heat exposure also caused an increase in the cutaneous moisture loss of the baboon and the chimpanzee but not in the galago. 4. ... | 1976 | 815544 |
| [the life cycle of the sarcosporidia. viii. sporocysts of sarcocystis bovihominis in the feces of rhesus monkeys (macaca rhesus) and baboons (papio cynocephalus)]. | | 1976 | 816348 |
| localized nocardiosis due to nocardia caviae in a baboon (papio cynocephalus). | nocardia caviae was identified as the causative agent of draining, multinodular swelling of the hand of a 16-yr-old female baboon (papio cynocephalus). the baboon's general physical condition was poor and menstrual cycles had ceased. the baboon improved after systemic and topical antibiotic therapy, but the lesion recurred after antibiotic treatment was discontinued. since excision of the mass, the baboon's physical condition has improved to the extent that regular menstrual cycles have resumed ... | 1975 | 1121169 |
| the order of movement of yellow baboons (papio cynocephalus). | the spatial organization of progressing baboons is thought to serve a protective function considered important in their adaptation to a terrestrial existence. progression positions of identified black infants, adult males, and other yellow baboons were determined from repeated samples of troop movements. spatial positioning by demographic class was similar to that previously found for three troops of anubis baboons living in two different habitats. such consistency across species and habitats se ... | 1975 | 1140751 |
| a study of baboon hemoglobin. | electrophoretic analysis of hemoglobin types of 409 baboons of various species, mostly from senegal, corresponds with the findings of other authors. baboon hemoglobin is homogeneous as a whole, but differs electrophoretically from that of other monkey species. however, a difference in the electrophoretic mobility of the nonhemoglobin fraction of papio anubis and papio cynocephalus suggests a possibly different amino-acid sequence. this information may be useful for the classification in doubtful ... | 1975 | 1146987 |
| dominance and reproduction in baboons (papio cynocephalus). | this monograph reports on a 14 month study of yellow baboons (papio cynocephalus) in the masai-amboseli game reserve, kenya. the study was an attempt to determine the relationship between agonistic dominance and reproductive success in male baboons and centered around testing a priority-of-access model of mating behavior. explicit criteria for determining dominance in baboons are presented and the consistency of dominance relationships through time is analyzed for all classes of individuals. rel ... | 1975 | 1170998 |
| detection of simian t-lymphotropic virus type i using the polymerase chain reaction. | to develop the polymerase chain reaction (pcr) for the detection of simian t-lymphotropic virus type i (stlv-i) infection, cell lines or peripheral-blood mononuclear cells (pbmc) from 2 non-human primate species [african green monkeys (agm), cercopithecus aethiops; baboon, papio cynocephalus] were evaluated for their stlv-i status using oligonucleotide primer pairs and probes specific for the tax and pol gene regions of the closely related human t-lymphotropic virus type i (htlv-i). these pcr re ... | 1992 | 1312066 |
| effect of clomiphene citrate upon periovulatory endometrial development in the baboon. | endometrial histology in baboons (papio cynocephalus anubis) was evaluated after five days of clomiphene citrate (cc) treatment initiated on either cycle day six (n = 8) or ten (n = 4). biopsies performed before and after a human chorionic gonadotropin (hcg) induced ovulation were compared to non-cc treated controls. although cc had a definite antiestrogenic effect on perineal skin, no significant effect of endometrial proliferation was demonstrable. | 1991 | 1865481 |
| [acute muramyl dipeptide-induced arthritis in the baboon papio cynocephalus]. | daily subcutaneous injections of muramyl dipeptide (mdp) for 14 days into yellow baboons (papio cynocephalus) caused polyarthritis with a prolific fibrinous exudate, but slight synovial lymphocytosis. in contrast, a single injection of bovine serum albumin (bsa) induced only a low-grade synovitis of the ipsilateral knee. when the schedules were combined the histological features suggested an additive effect between the reactions to bsa and to mdp. larger amounts of mdp diminished the severity of ... | 1991 | 1872047 |
| is lipsmacking an indicator of social status in baboons? | lipsmacking is performed by many old world monkey species, and some studies of baboons and macaques suggest that lipsmacking may be associated with social status. we studied 60 adult anubis baboons (papio cynocephalus anubis) for 18 months, measured social status and the rate of lipsmacking, and used these data to test the hypothesis that lipsmacking is related to social status. our results indicate that social status and lipsmacking were not significantly correlated for either males or females. ... | 1991 | 1937282 |
| diets of yearling female primates (papio cynocephalus) predict lifetime fitness. | the foraging of yearling baboons (papio cynocephalus) was studied in amboseli national park, kenya. the nutrient content of the diets of individual females was compared with the composition of energy-maximizing optimal diets. energy in the diets of all individuals fell appreciably short of their respective optima. nonetheless, linear combinations of just two variables, protein intakes in excess of requirements and proximity of energy intakes to those specified in the optimal diets, were sufficie ... | 1991 | 1988942 |
| vitamin a metabolism in the baboon eye. | the vitamin a metabolism of eight baboon (papio cynocephalus anubis) eyes were examined. high performance liquid chromatography was utilized for quantitative analysis of retinyl esters and retinol in four eyes. retinyl ester levels in pigment epithelium (pe) were greater (3043 pmol/eye) than in neuroretina (1084 pmol/eye). however, the reverse was true for retinol levels (neuroretina = 4610 pmol/eye; pe = 1451 pmol/eye). neuroretina and pe of four remaining eyes were analyzed for retinyl ester h ... | 1990 | 2372694 |
| complete amino acid sequence of gamma chain of fetal hemoglobin of japanese macaque (macaca fuscata). | the complete amino acid sequence of the gamma chain of japanese macaque (macaca fuscata) was deduced from sequence analysis of its tryptic peptides and a few other peptides. three amino acid residues are substituted compared to the human gamma chain, 77his (human) to 77asn (japanese macaque), 104lys to 104arg and 135thr to 135 ala. the primary structure of the gamma chain of japanese macaque is the same as that of rhesus macaque (macaca mulatta) (2) and yellow baboon (papio cynocephalus) (3). di ... | 1986 | 2420747 |
| prevalence of antibodies to siv in baboons in their native habitat. | we have documented rare infection of baboons in their native habitat with simian immunodeficiency virus (siv). of 124 sera collected from yellow baboons in central tanzania, two gave high readings by sivagm elisa (greater than 1.0) and moderate by sivmac elisa (0.5-1.0). these two sera gave strong reactions to the major sivagm proteins, including gp130, by western blot analysis; their reactivity to sivmac protein was considerably weaker. similar testing of 155 sera from olive baboons of ethiopia ... | 1989 | 2543434 |
| refined structure of baboon alpha-lactalbumin at 1.7 a resolution. comparison with c-type lysozyme. | the solution of the structure of alpha-lactalbumin from baboon milk (papio cynocephalus) at 4.5 a resolution using the isomorphous replacement method has been reported previously. initial refinement on the basis of these low-resolution studies was not successful because of the poor isomorphism of the best heavy-atom derivative. because of the striking similarity between the structure of lysozyme and alpha-lactalbumin, a more cautious molecular replacement approach was tried to refine the model. ... | 1989 | 2769757 |
| experimental infection of baboons (papio cynocephalus anubis) with chlamydia pneumoniae strain 'twar'. | two infant baboons (papio cynocephalus anubis) were inoculated with chlamydia pneumoniae strain 'twar', one in the conjunctiva, nasopharynx and oropharynx, the other in the trachea. both remained well during 8 weeks of observation. c. pneumoniae infection persisted for at least 8 weeks after inoculation. chlamydia pneumoniae seems to be of low virulence in baboons and capable of causing chronic infection. | 1989 | 2778341 |
| characterization of a human lymphoblastoid cell line permanently modified by simian foamy virus type 10. | simian spumavirinae serotype, sfv10, of a papio cynocephalus baboon, was used to infect a human lymphoblastoid cell line, lv2. permanent growth and morphological alterations of infected cells occurred, even though no viral particles were detected. evidence for the presence of viral genomes in the modified cell line is provided indirectly from immunological studies and induction experiments followed by coculture procedures. the permanently modified cell line obtained (lv2-fb10) is an interesting ... | 1987 | 2826791 |
| embryotoxicity and maternal serum concentrations of medroxyprogesterone acetate (mpa) in baboons (papio cynocephalus). | a single dose of mpa (depo-provera; upjohn co.; usa) was administered intramuscularly on day 27 (+/- 2) of gestation to three dosage groups of pregnant baboons. the dosage expressed as mg/kg corresponded to 1 (2.5 mg/kg), 10 (25 mg/kg) and 40 (100 mg/kg) times the human contraceptive dose equivalent (hde) based on body weight. injectable mpa was not teratogenic in baboons at 1x hde. the teratogenicity was confined to the higher doses which included malformations of the external genitalia at 10x ... | 1985 | 2935368 |
| experimental herpes neonatalis in sa 8-infected baboons (papio cynocephalus). | 13 newborn baboons were experimentally infected with a baboon-derived herpesvirus sa 8-strain. intratracheal infection produced herpetic tracheobronchopneumonia, intravenous inoculation resulted in adrenal necrosis similar to that in human neonatal herpes infection. | 1985 | 2987612 |
| hepatocystis in populations of baboons (papio hamadryas s.l.) of tanzania and ethiopia. | bloodsmears from 119 yellow baboons (papio hamadryas cynocephalus) in six groups in mikumi national park, tanzania, and from 189 olive (p.h. anubis) hamadryas (p.h. hamadryas) and hybrid baboons in three groups in awash national park, ethiopia showed differing levels of infection with hepatocystis simiae. 0% to 42% in the tanzanian groups were carriers of the parasite but none of the ethiopian baboons was positive. the remarkable absence of h. simiae in the ethiopian baboons is believed to be re ... | 1988 | 3184165 |
| case of disseminated african histoplasmosis in a baboon. | an adult red baboon (papio cynocephalus papio) had a severe disseminated case of african histoplasmosis (histoplasma capsulatum var. duboisii) with skin lesions from small pustules to ulcerative granulomas. osteolytic lesions were seen radiographically. treatment with ketoconazole for 6 months was unsuccessful. | 1988 | 3184166 |
| distribution of androgen receptor in microdissected brain areas of the female baboon (papio cynocephalus). | we measured androgen receptors in the brain and pituitary of 4 female baboons (papio cynocephalus) by the in vitro binding of methyltrienolone (r1881) to cytosols from 17 brain subregions as well as anterior and posterior pituitaries. high levels of ar were detected in anterior (22.1 +/- 7.1 (s.e.m.) fmol/mg protein) and posterior pituitary (12.6 +/- 3.3 fmol/mg protein). in brain tissue, the highest androgen receptor levels were found in the infundibular nucleus/median eminence (9.4 +/- 2.3 fmo ... | 1988 | 3259151 |
| inoculation of baboons and macaques with simian immunodeficiency virus/mne, a primate lentivirus closely related to human immunodeficiency virus type 2. | a primate lymphotropic lentivirus was isolated on the human t-cell line hut 78 after cocultivation of a lymph node from a pig-tailed macaque (macaca nemestrina) that had died with malignant lymphoma. this isolate, originally designated m. nemestrina immunodeficiency virus (mniv) and now classified as simian immunodeficiency virus (siv/mne), was inoculated intravenously into three juvenile rhesus monkeys (macaca mulatta), three juvenile pig-tailed macaques (m. nemestrina), and two juvenile baboon ... | 1988 | 3285032 |
| thyroid hormone levels and cigarette smoking in baboons. | using a primate animal model, two studies were undertaken to examine the effects of cigarette smoking on thyroid hormone levels. in study 1, mean total triiodothyronine (total t3) and mean total thyroxine (total t4) levels were measured in two groups of baboons (papio cynocephalus) who were taught to smoke cigarettes using operant conditioning techniques. the smokers were divided into established and naive smokers according to pack-years of exposure. a control group of never-smoker baboons was i ... | 1988 | 3340630 |
| embryotoxicity of sex steroidal hormone combinations in nonhuman primates: i. norethisterone acetate + ethinylestradiol and progesterone + estradiol benzoate (macaca mulatta, macaca fascicularis, and papio cynocephalus). | two sex steroid hormone combinations which have been used clinically as tests for detection of early pregnancy were examined for embryotoxic effects in macaques and baboons. norethisterone acetate and ethinyl estradiol (nea + ee) were orally administered to rhesus and cynomolgus monkeys and baboons at dosages ranging from one to 1,000 times the human dose equivalent (hde) during days 20-50 of pregnancy. progesterone and estradiol benzoate (p + eb) were delivered by two to six intramuscular injec ... | 1987 | 3563930 |
| early implantation and embryonic development of the baboon: stages 5, 6 and 7. | implantation stages of the olive baboon, papio cynocephalus anubis, showing embryonic development equivalent to carnegie stages 5, 6 and 7 of development, were collected by hysterotomy and examined histologically. the younger specimens (stage 5) consisted of a thick trophoblastic plate composed of cytotrophoblast and syncytiotrophoblast with multiple small clefts, and a bilaminar disk embryo with a small slit-like amniotic cavity. an epithelial plaque response was present in the uterine epitheli ... | 1987 | 3631530 |
| baboon diet: a five-year study of stability and variability in the plant feeding and habitat of the yellow baboons (papio cynocephalus) of mikumi national park, tanzania. | the habitat and plant feeding of 64 well-habituated, individually identified adult male and female yellow baboons was studied for 5 years at mikumi national park, tanzania. variation across the years showed that a study of only one or two years would have been incomplete and misleading. the list of baboon food species obtained from mikumi is considerably larger and more diverse than any previously reported. one to six plant parts were eaten from each of more than 180 species. the 25 most common ... | 1987 | 3653819 |
| leishmania major: the suitability of east african nonhuman primates as animal models for cutaneous leishmaniasis. | the susceptibility of four species of east african nonhuman primates to experimental infection with leishmania major was investigated. four syke's monkeys (cercopithecus mitis), two vervet monkeys (cercopithecus aethiops), two baboons (papio cynocephalus), and two brown bushbabies (galago garnettii) were each inoculated intradermally on the left eyelid, left ear, and nose with 0.1 ml of medium containing 1 x 10(7) promastigotes of a characterized l. major strain. all the nonhuman primates except ... | 1987 | 3678449 |
| insect and meat eating among infant and adult baboons (papio cynocephalus) of mikumi national park, tanzania. | it has been suggested that baboon predation upon vertebrates may tend to peak in the dry season because insect food is then less available, and that males obtain animal nutrients primarily from vertebrates whereas other troop members obtain them primarily from invertebrates. the development of meat and insect eating by 22 male and 24 female infants studied for 25 months was compared with that of 18 male and 46 female adults studied for 37 months. systematic sampling allowed quantitative comparis ... | 1986 | 3728648 |
| [arterial vascularization of the sino-atrial and atrio-ventricular nodes and frequency of coronary artery branches in papio erxleben, 1777]. | the arterial blood supply to the sino-atrial (s-a) and atrio-ventricular (a-v) nodes was studied in 63 baboon hearts (papio cynocephalus and papio hamadryas). the arterial coronary injection was made with latex neoprene (23 hearts), a latex and lead oxide mixture (30 hearts) and polyester resin (10 hearts) for dissection, radiographic and corrosion cast studies, respectively. the s-a artery is a long recurrent left coronary branch (92.1%) or an ascendant less long right coronary branch (7.9%). t ... | 1986 | 3744187 |
| experimental infection of the baboon (papio cynocephalus) with echinococcus granulosus of camel, cattle, sheep and goat origin from kenya. | in different areas of the world, strains of echinococcus granulosus have been described which appear to vary in their infectivity, and laboratory primates have been used as indicators of their infectivity to man. this phenomenon was evaluated in kenya for hydatid material of human, camel, cattle, sheep and goat origin. viable eggs, produced by experimental infections in dogs with larval material from all the above intermediate hosts, were fed separately to four baboons (papio cynocephalus) in ea ... | 1986 | 3745875 |
| the suitability of east african primates as animal models of visceral leishmaniasis. | the susceptibility of four east african primate species to experimental infection with leishmania donovani was investigated. vervet monkeys (cercopithecus aethiops), sykes monkeys (c. mitis) and baboons (papio cynocephalus) all supported low grade infections for periods ranging between four and eight months and subsequently showed evidence of self-cure. greater bushbabies (galago crassicaudatus) remained completely refractory throughout the course of the experiment. the significance of hepatic h ... | 1986 | 3810791 |
| hand-rearing baboons for laboratory investigations. | to conduct laboratory studies in unsedated animals that were similar anatomically and physiologically to man, five full term baboons (four papio cynocephalus anubis, one papio cynocephalus cynocephalus) were hand-reared. these infants were used as unsedated animal models in short-term lung clearance studies conducted from birth to 2 years of age. the hand-rearing techniques described here encouraged the formation of an infant-human rearer bond that permitted us to control the level of expressed ... | 1986 | 3821060 |
| effect of dexamethasone on serum protein extravasation in experimental brain infarcts of monkey: an immunohistochemical study. | experimental brain infarcts were produced in 12 adult baboons (papio cynocephalus) by transorbital permanent clipping of the left middle cerebral artery. one group (seven monkeys) received daily injections of 1 mg/kg dexamethasone, starting 1 h after vascular occlusion and continuing till the end of the experiment. another group (five monkeys) was not treated. one week after vascular occlusion the volume of infarcts and peri-infarct edema was estimated morphometrically on histological sections, ... | 1985 | 3883688 |
| tuberculosis in wild olive baboons, papio cynocephalus anubis (lesson), in kenya. | several wild olive baboons from a single troop in the masai mara game reserve, kenya were observed to be lethargic and emaciated. five were trapped and tuberculin tested by intradermal inoculation of 0.1 cc (100 iu) mammalian old tuberculin in the upper eyelid. two of the five showed positive reaction at 72 hr and were examined at necropsy. gross lesions in both animals consisted of multiple nodules with caseation in the lung, spleen and tracheobronchial lymph nodes. there were multiple granulom ... | 1985 | 3889385 |
| antibiotic resistance and population structure in escherichia coli from free-ranging african yellow baboons. | two collections of escherichia coli from human hosts and one from free-ranging african yellow baboons were examined for the ability to utilize various sugars (biotype) and for resistance to antibiotics. the frequency of antibiotic resistance in the e. coli flora of baboons that feed regularly in village garbage dumps was found to be no greater than that in baboons not associated with human habitation. the frequency of antibiotic resistance in e. coli isolated from baboons is similar to that in e ... | 1985 | 3909963 |
| timing of the luteal-placental shift in the baboon (papio cynocephalus). | normally cycling female baboons (papio cynocephalus) were mated with males of proven fertility during the periovulatory period. after pregnancy was confirmed, the corpus luteum-bearing ovary was removed (cl-ovx) at day 18 (n = 1), day 20 (n = 4), day 25 (n = 3), or day 30 (n = 4) of gestation. upon cl-ovx at day 18 or 20, there was an immediate decline in plasma progesterone to basal levels, and pregnancy was not maintained. after cl-ovx on days 25 or 30, there was a transient, small decline in ... | 1986 | 3943483 |
| antibiotic-resistant bacteria in wild primates: increased prevalence in baboons feeding on human refuse. | we examined three groups of wild baboons (papio cynocephalus) in amboseli national park, kenya, to determine the prevalence of aerobic antibiotic-resistant fecal bacteria in nonhuman primates with and without contact with human refuse. using standard isolation and replica plating techniques, we found only low numbers of antibiotic-resistant gram-negative enteric bacteria in two groups of baboons leading an undisturbed existence in their natural habitat and having limited or no contact with human ... | 1985 | 4004213 |
| effects of dietary polyunsaturated and saturated fats on lipoproteins in the baboon. | the effects of 2 different dietary fats (40% of calories from corn oil or coconut oil), in the presence of high-dietary cholesterol (1.7 mg/kcal), on the lipoprotein profiles of baboons (papio cynocephalus sp) were studied by analytic ultracentrifugation, gradient gel electrophoresis (gge), and heparin-manganese chloride precipitation. relative to the corn oil (polyunsaturated fat) diet, the coconut oil (saturated fat) diet significantly increased total serum cholesterol by 43% (p less than 0.00 ... | 1985 | 4074459 |
| duration of the third stage of labor in a female yellow baboon from mikumi national park, tanzania. | in human obstetrical practice, placental retention is defined as failure of placental expulsion within 45 min of fetal delivery, and is of concern given the potential for hemorrhage or infection. because of the difficulty in observing the parturition event, few data exist on variation in the duration of this stage of labor in free-ranging primates. in mikumi national park in tanzania we recorded an interval in excess of 2 h between delivery of the infant and expulsion of the placenta in a yellow ... | 1985 | 4076926 |
| effects of cigarette nicotine content on smoking behavior of baboons. | human cigarette smokers modify the way in which they smoke cigarettes of differing nicotine content, apparently to maintain nicotine exposure at a preferred level. the effects of changing from moderate to high or low nicotine content cigarettes were examined in 11 baboons (superspecies papio cynocephalus) trained to smoke cigarettes for water rewards. relative to the moderate nicotine content cigarette, the animals took significantly (p less than .05) more puffs on the high nicotine content ciga ... | 1985 | 4083101 |
| study of the photo-sensitivity of papio anubis, papio cynocephalus and of their cross-mating. | | 1970 | 4194029 |
| fetal infection of the baboon (papio cynocephalus) with vaccinia virus. | | 1973 | 4200608 |
| commensals and parasites of african baboons (papio cynocephalus l. 1766) captured in rift valley province of central kenya. | | 1973 | 4203715 |
| experimental infection of african baboon (papio cynocephalus) with brugia malayi. | | 1974 | 4204969 |
| carbonic anhydrase isoenzymes in nine troops of kenya baboons, papio cynocephalus (linnaeus 1766). | | 1974 | 4212980 |
| controlled investigations in baboons (papio cynocephalus) on transmission of sv-5 virus by contact. | | 1967 | 4291701 |
| hemorrhagic-necrotic enteritis in a baboon (papio cynocephalus) due to vibrio fetus. | | 1972 | 4343333 |
| experimental herpesvirus infection of baboons (papio cynocephalus) and african green monkeys (cercopithecus aethiops) and recovery of virus by tissue explants. | | 1973 | 4362931 |
| persistence and spread of influenza virus (a2-hong kong) in normal and poly i.c. treated baboons (papio cynocephalus). | | 1970 | 4992080 |
| [anguillulosis due to strongyloides fülleborni o. von linstow in the cynocephalus (papio cynocephalus) in senegal: its treatment by the dimethyl ester of 2-2-2-trichloro-1-hydroxyethylphosphonic acid]. | | 1967 | 5628194 |
| cellular immunology in the baboon (papio cynocephalus): examination of structural and functional characteristics of adult and fetal lymphoid cells. | we studied structural and functional characteristics of lymphocytes from adult and fetal baboons (papio cynocephalus). flow cytometry with monoclonal antibodies to human lymphocyte antigens and plant lectins was used to define expression of surface antigens on lymphocytes from adult and 140 day fetal baboons (term = 180 days). major t cell antigenic determinants on adult and fetal baboon lymphocytes were the tp50, tp32-45, and p45 glycoproteins detected by monoclonal reagents t11, okt8, and okt1 ... | 1984 | 6084035 |
| changes in the gamma chain heterogeneity of hemoglobin f of the baboon (papio cynocephalus) postnatally and after partial switching to hemoglobin f production by various stimuli. | the postnatal switch from hemoglobin (hb) f to hb a in the baboon (papio cynocephalus) occurs somewhat more rapidly than in humans. minor components which are related to hb f and hb a are also present and show reciprocal rise and fall. the baboon produces two types of gamma chain presumably from nonallelic genes. these have either an isoleucyl (i gamma) or a valyl (v gamma) residue in position 75. as in the human case with g gamma and a gamma chains, the ratio i gamma to v gamma chains changes d ... | 1983 | 6186664 |
| the effect of medroxyprogesterone acetate (depo-provera) on prenatal development in the baboon (papio anubis): a preliminary study. | six female olive baboons (papio cynocephalus anubis) were treated with a single dose of 150 mg of depo-provera i.m. at day 30 of pregnancy, approximately three times the human dose equivalent on a body weight basis. fetectomies were performed at day 100 of gestation. the body weights and measurements of the five live fetuses were comparable to age-matched controls and no gross or histologic abnormalities were seen. the dead fetus was in an advanced state of decomposition. this preliminary study ... | 1984 | 6238440 |
| [experimentally induced herpesvirus sa 8 -- encephalitis in kenya baboons (papio cynocephalus) (author's transl)]. | | 1980 | 6259804 |
| isolation of an enterovirus (sv19) from baboons (papio cynocephalus). | inoculation of newborn mice with fecal samples from approximately 200 baboons (papio cynocephalus) yielded an enterovirus (sv19) from four different animals. this virus previously had been found only in asian monkeys (macaca sp). | 1981 | 6264223 |
| [experimentally induced herpesvirus sa 8-pneumonia (bronchopneumonia) in kenya baboons (papio cynocephalus) (author's transl)]. | captive baboons of three age groups were experimentally infected with herpesvirus sa 8-strain 0430. intravenous inoculation of the virus induced minor, transient, interstitial pneumonia of a nonspecific type in newborn baboons. intratracheal inoculation, in contrast, invariably produced multifocal or diffuse necrotizing inclusion body bronchopneumonia within two days in newborn, two months and one year old baboons. differences in the outcome of the experimental intratracheal infections were noti ... | 1981 | 6269276 |
| chemical inhibition of foamyvirus in primary baboon (papio cynocephalus) kidney cells. | this report describes the conditions for the use of aluminum chloride (alcl3) in growth and maintenance media for the suppression or inhibition of simian foamyviruses (sfv) in primary baboon kidney (bak) and rabbit kidney (rk) cell cultures. when rk cells were planted in medium containing alcl3, infected with sfv, and passaged, the growth of sfv was suppressed or inhibited by the presence of alcl3. with this method, bak cells yielded higher viral titers after infection with various viruses, thus ... | 1982 | 6286700 |
| infection of baboons ("papio cynocephalus") with rotavirus (sa11). | a recent survey of nonhuman primate sera indicated that antibody to a rotavirus (sa11) was prevalent among a wide spectrum of animals. both new and old world species were found with antibody, many with surprisingly high titers (1:320). whether or not infection per se was due to sa11 or an antigenically closely related agent could not be determined by that study; however, it is apparent from this study as well as from a survey of the literature that natural as well as experimental infection of no ... | 1983 | 6307781 |
| identification of specific fsh binding sites in the testes of adult monkeys of different species. | the interaction of 125i-labelled hfsh with primate testicular tissue from 4 species of adult monkeys (macaca mulatta, m. nemestrina, m. fascicularis and papio cynocephalus) was investigated. 125i-labelled hfsh binding to a particulate fraction (p1, 40 000 g) of frozen testes was highly specific and saturable. displacement curves generated using the p1 fraction of testes from the 4 species and 125i-labelled hfsh and unlabelled fsh were very similar. the binding of fsh to the monkey testicular rec ... | 1984 | 6321720 |
| novel viral sequences related to human t-cell leukemia virus in t cells of a seropositive baboon. | antibodies reactive with proteins of human t-cell leukemia virus (htlv) can be found in old world monkeys. a t-lymphocyte cell line established from a seropositive baboon (papio cynocephalus) was analyzed for the presence of viral dna sequences. the provirus found in these cells was related to but distinct from htlv subgroup i. these results add to recent evidence from human studies that htlv represents a spectrum of infectious t-lymphotropic retroviruses that includes closely and distantly rela ... | 1984 | 6322297 |
| synovial response of papio cynocephalus to exogenous antigen: histological and immunoperoxidase observations. | acute experimental synovitis was produced by intra-articular challenge of 3 baboons (papio cynocephalus) sensitised with ovalbumin. haemagglutination tests revealed high titres of circulating antiovalbumin antibody. measurements were made of articular diameter, circumference, and temperature before the animals were killed on days 1, 5, and 20. the sterile synovitis was investigated microscopically and by immunoperoxidase methods. igg, igm, iga, c3, and fibrin were identified within the synovial ... | 1983 | 6349553 |
| initial characterization of a peripheral blood mononuclear cell chemoattractant derived from cultured arterial smooth muscle cells. | a mononuclear cell chemoattractant of high specific activity produced by baboon (papio cynocephalus) aortic medial smooth-muscle cells (smcs) in culture has been partially characterized. smooth-muscle cells, between the third and eighth passage, were grown to confluence in medium 199 containing 10% fetal calf serum and then incubated for 24 hours in either serumless medium (neuman and tytell) or medium 199 containing 0.2% bovine serum albumin. the 24-hour smc-conditioned medium was fractionated ... | 1984 | 6391189 |
| immune complex glomerulonephritis in baboons (papio cynocephalus) with indwelling intravascular catheters. | baboons with long term, indwelling, intravascular catheters developed clinical signs of renal and hepatic impairment. these included proteinuria and hypoalbuminemia without edema, and albumin to globulin ratios were reversed. serum igm, igg, rheumatoid factor, and liver enzyme concentrations were above normal. immunofluorescent staining of renal glomerular capillary loops was positive for igg, igm, b1c, and c4. major microscopic lesions were membranoproliferative glomerulonephritis, chronic acti ... | 1981 | 6458737 |
| pubertal endocrinology of the baboon: adrenarche. | the concentration of the adrenal steroids dehydroepiandrosterone (dha) and dehydroepiandrosterone sulfate (dha-s) was measured by radioimmunoassay in plasma of 134 baboons (papio cynocephalus) from 0 to 17 yr of age. plasma androstenedione (delta 4-a) was also measured in 289 baboons encompassing the same age range. the concentration of dha was persistently high from birth to adulthood, exceeding 700 ng/dl at all ages. this differs markedly from the human pattern in which dha concentrations fall ... | 1981 | 6459032 |
| micro-system for the primary immunization of baboon (papio cynocephalus) peripheral blood mononuclear cells with sheep erythrocytes in vitro. | a micro-culture system for the stimulation of baboon peripheral blood mononuclear cells (pbmc) with sheep erythrocytes (srbc) in vitro was established. pbmc cultures in 96-well microtiter plates were maintained in 300 microliter of culture medium containing a murine mixed lymphocyte reaction (mlr) supernatant and srbc. cultures of 7.5 x 10(5) pbmc and 6 x 10(6) srbc resulted in the highest anti-srbc plaque-forming cell (pfc) response. it was also determined that the presence of 50 microliter of ... | 1982 | 6460063 |