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the structure and function of acid proteases. vii. distribution and some properties of acid proteases in monkey tissues.1. the distribution of acid protease activity in various tissues of japanese monkey (macaca fuscata fuscata) was investigated with hemoglobin as a substrate at ph 3.0. the activity per protein weight in crude extracts was highest in spleen and lung, and decreased in the order: spleen, lung greater than kidney, testis greater than brain greater than liver, placenta greater than thyroid gland, muscle. the activity in crude muscle extract was about one-tenth those of spleen and lung. the activity p ...197714947
decreased smooth muscle side effects with 16, 16-dimethyl-trans-delta2-pge1 methyl ester in japanese monkey (macaca fuscata fuscata).the smooth muscle stimulating activity of a new pge1 analog, 16, 16-dimethyl- trans delta2 -pge1 methyl ester (ono-802) was evaluated by simultaneously recording the emg of the uterus and intestines, along with urinary bladder pressure, and blood pressure in pregnant and non-pregnant japanese monkeys (macaca fuscata fuscata). single intravenous injections of ono-802 in increasing dosages (0.2-5 microgram/kg) were found to be 50-100 times or more effective in inducing uterine contraction than pgf ...197896494
neural lateralization of species-specific vocalizations by japanese macaques (macaca fuscata).five japanese macaques and five other old world monkeys were trained to discriminate among field-recorded japanese macaque vocalizations. one task required discrimination of a communicatively relevant acoustic feature ("peak"), and a second required discrimination of an orthogonal feature of the same vocalizations ("pitch"). the japanese animals more proficiently discriminated the peak feature when stimuli were presented to the right ear (primarily left cerebral hemisphere), as opposed to the le ...197899817
uterine contractility and plasma levels of steroid hormones after intravaginal treatment of pregnant japanese monkeys (macaca fuscata fuscata) with 16,16-dimethyl-trans-delta2-prostaglandin e-1 methyl ester.intravaginal treatment with a pge-1 analogue (ono-802) resulted in strong uterine contractions with a high frequency which lasted for more than 3 h. when 20-50 microgram ono-802/kg were administered intravaginally 5 times every 3 h in 5 pregnant animals, vaginal bleeding started by 6 h and abortion occurred by 26 h after the initial treatment. there were no significant side effects. plasma levels of steroid hormones, especially progesterone and 20alpha-dihydroprogesterone, fluctuated initially a ...1979108397
cerebellar cortical atrophy in an adult japanese macaque. 1979111404
surveys of simian malaria in japan.the survey of simian malaria in japan which had been conducted since 1965 showed that no japanese monkeys (macaca fuscata fuscata and macaca fuscata yakui) were infected with malaria parasites. most interestingly, however, babesia sp. was found in 4 (4.3%) of 93 macaca fuscata yakui which had been reared in a monkey park. as for the monkeys imported from abroad, plasmodium was only found in macaca irus from southeast asia, namely, p. inui (14.1-25.0%), p. cynomologi (0.6, 3.2%) and p. coatneyi ( ...1979116437
laparoscopic observations of follicular rupture in the japanese macaque (macaca fuscata). 1977142148
seasonal changes of plasma estradiol and progesterone in the japanese monkey (macaca fuscata fuscata).the plasma levels of estradiol and progesterone in 5 mature female japanese monkeys (macaca fuscata fuscata) throughout a breeding and nonbreeding season were measured by radioimmunoassay. as the breeding season approached, plasma estradiol levels started to increase and a few elevations were detected. however, neither a plasma progesterone rise nor menstrual bleeding was seen. menstrual bleeding began in december and recurred regularly 4 or 5 times at 4 week intervals until april. during this p ...1977401026
progesterone levels in the japanese monkey (macaca fuscata fuscata) during the breeding and nonbreeding season and pregnancy.progesterone levels were determined in the peripheral blood of the japanese monkey during the menstrual cycle, breeding season, nonbreeding season, and gestation. progesterone levels averaged less than 0.3 ng/ml in the earlier follicular phase, rose to maximum values of 3.8 ng/ml approximately eight days before menses, and declined to less than 1.0 ng/ml before menstruation. progesterone levels during the nonbreeding season were comparable with those during the early follicular phase. in pregnan ...1977406405
thermoregulation of the japanese macaque living in a snowy mountain area.a field investigation was conducted to study the thermoregulatory responses in nine japanese macaques (macaca fuscata) living in a snowy mountain area, jigoku-dani (hell valley, about 1,000 m above sea level) in shiga heights in central japan in late january 1975. at about the same time, a laboratory study was made on four japanese macaques reared in mild climate in an outdoor cage in inuyama city. in the hell valley (hv) monkeys, no significant change in metabolic rate was observed at ta betwee ...1977410988
age and sexual behavior of japanese macaques (macaca fuscata).the sexual behavior of the arashiyama west troop, a natural semi-free-ranging troop of japanese macaques, was studied during the 1973-1974 and 1974-1975 breeding seasons. the troop was transported intact from japan to its current location in south texas. there they have been free to move about in a 42.2-hectare electric fence enclosure. this report describes the relationships among age, aging, and sexual behavior. males beginning at the age of 2.5 years were observed to series-mount estrous fema ...1978416810
intra-group variations in the dental eruption sequence of macaca fuscata fuscata.the purpose of this investigation was to establish general trends of intra-group variations in the dental eruption sequence of a semi-wild troop of maca fuscata fuscata. dental impressions were taken on 128 animals of varying ages. the analysis of the dental casts revealed sexual dimorphism in sequence and timing of eruption.1977604224
[on corpora amyrlacea in the central nervous system of macaca fuscata fuscata (author's transl)]. 1975814566
effect of t-shaped progesterone-releasing system on contraceptive efficacy and menstrual cycle regularity in japanese monkeys.twenty-seven sexually mature japanese monkeys (macaca fuscata fuscata) weighing 6 to 8 kg were used to evaluate and characterize the local and systemic effects of a t-shaped progesterone-releasing system (uts) following transabdominal insertion into the uterus. none of five experimental animals conceived, while four of five sham-operated control animals and all intact animals conceived. the general physical appearance, behavior, and clinical blood chemical titer of animals receiving the uts were ...1976819310
effect of clipping the coat of the japanese macaque (macaca fuscata) on the thermoregulatory responses.effect of clipping the coat of the japanese macaque on thermoregulatory responses was studied. heat production was significantly increased in clipped animals in comparison without clipped coats at ambient temperatures ranging from 5 to 25 degrees c. at ambient temperatures of 5, 15, and 25 degrees c tissue thermal conductance and cooling constant were significantly higher in clipped animals. clipped animals could maintain thermal equilibrium at an ambient temperature of 5 degrees c, conpensating ...1976823355
the effect of prostaglandins on the electromyogram and motility of the monkey uterus and oviduct in late pregnancy and postpartum.the electromyogram of the monkey (macaca fuscata fuscata and macaca mulatta) uterus in labor presents spike bursts which accompany the rising intrauterine pressure. asynchronous localized electrical activity develops into synchronous activity during the course of labor. the early postpartum uterus shows an irregular pattern or continuous small bursts of spikes. during labor it responds markedly to prostaglandins (pgs); this declines in postpartum. direct intrauterine injection of pgf2a is effect ...1977875007
a comparison of thermoregulatory responses in the japanese macaque (macca fuscata) and the crab-eating macaque (macaca irus) during cold exposure.thermoregulatory responses in four male adult japanese macaques and four male adult crab-eating macaques, weighing 6-12 kg and 6.2-8 kg, respectively, were compared at ambient temperatures (ta) ranging from 5 degrees c to 25 degrees c. the average values +/- s.e. for some physiological measurements made at ta of 25 degrees c in the japanese macaque and the crab-eating macaque, respectively, were as follows: resting metabolic rate; 47.6 +/- 5.0 and 42.5 +/- 1.7 w/m2; tissue conductance; 11.9 +/- ...19751152303
influences of female partner preference on potential reproductive outcome in japanese macaques.the immediate effects of female partner preference on male mating behaviors and its potential influence on male reproductive success and conception in the japanese macaque (macaca fuscata) were analyzed. although male dominance interactions probably led to low-ranking males having more single-day consortships and high-ranking males more multi-day consortships, dominant males were unable to prevent females from mating with preferred subordinate males. ultimately, there was no marked difference in ...19921297630
detection of simian t-lymphotropic virus type i using the polymerase chain reaction.to develop the polymerase chain reaction (pcr) for the detection of simian t-lymphotropic virus type i (stlv-i) infection, cell lines or peripheral-blood mononuclear cells (pbmc) from 2 non-human primate species [african green monkeys (agm), cercopithecus aethiops; baboon, papio cynocephalus] were evaluated for their stlv-i status using oligonucleotide primer pairs and probes specific for the tax and pol gene regions of the closely related human t-lymphotropic virus type i (htlv-i). these pcr re ...19921312066
fine structure of the dorsal lingual epithelium of the japanese monkey macaca fuscata fuscata.filiform papillae, which were densely distributed all over the dorsal surface of the lingual body, were crown-shaped, with a central, circular area that sloped in the anterior direction and several branches that surrounded it in a semicircle from the back of the central area. dome-shaped, fungiform papillae were scattered among these filiform papillae. at the posterior end of the lingual body, there were four circumvallate papillae. prominent microridges and elevated intercellular borders were w ...19921382355
functional significance of female japanese macaque copulatory calls. 19921398344
microvascular architecture of the lingual papillae in the japanese monkey (macaca fuscata fuscata).the microvascular architecture of all kinds of lingual papillae in the japanese monkey was investigated on plastic corrosion casts and epithelium-separated specimens under a scanning electron microscope. three kinds of the filiform papillae were observed; the circularly-arranged papillae with a small papilla in the center on the lingual apex, a simple large conical papilla with a bilateral pair of spines on the lingual body and the aggregated filiform papillae on the top of an epithelial project ...19921436961
histological and histochemical investigations on japanese lizard esophagus.the authors previously investigated the bottle-shaped glands distributed in the lamina propria mucosae of the japanese lizard and gecko. we made two sets of sections of the japanese lizard at that time. the numerical values of the physical dimensions of the two individuals were as given table 1, showing that no. 2 was slightly smaller. moreover we found very unusual tissue in the lower portion of the esophagus of no. 2. therefore we excluded this individual from the preceding investigations. how ...19921620528
species differences in the coexistence of 5-hydroxytryptamine and substance p in presynaptic boutons in the cervical ventral horn.substance p (sp)- and 5-hydroxytryptamine (5-ht)-containing presynaptic boutons in the cervical ventral horn were studied in chicken, hamster, rat and monkey spinal cords, using pap and protein a-gold double-labeling techniques in conjunction with monoclonal antibodies. in the chicken, the pap method demonstrated that sp-immunoreactive boutons contained large spherical dense-cored vesicles (dcvs) whereas 5-ht-immunoreactive boutons displayed both elongated and spherical dcvs. using the protein a ...19911715239
effects of an intrauterine copper device on serum copper, endometrial histology, and ovarian, hepatic, and renal functions in the japanese monkey (macaca fuscata fuscata).a copper intrauterine device (cu-iud) was inserted transabdominally into the uterine cavity of eight japanese monkeys (macaca fuscata fuscata) for 4 to 6 months, and effects on various organ functions were examined. results showed no significant effects on the menstrual cycle length, serum levels of lh, estradiol-17 beta, progesterone or clinical biochemical data such as serum copper, glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, lactic dehydrogenase, and blood urea nitrogen. ...19911757969
the jump as a fast mode of locomotion in arboreal and terrestrial biotopes.the jump is always used for locomotion. for its execution in arboreal and terrestrial biotopes the requirements are of somewhat different nature. in an arboreal biotope the jump is characterized by a rapid progression through discontinuous substrates and the ability to take off from a small area and a secure landing on a spot. this requires well coordinated movements in all phases of the jump. on the ground, the jump is less frequent and often used for crossing obstacles or gaps. in primates bot ...19911887664
seasonal changes in plasma concentrations of immunoreactive inhibin and testicular activity in male japanese monkeys.seasonal changes in plasma immunoreactive (ir-) inhibin, testosterone, lh, and fsh concentrations were examined in five sexually mature male japanese monkeys (macaca fuscata fuscata) housed indoors individually, to explore the reproductive cyclicity in the male. blood samples were collected monthly throughout one year, and testicular size, semen volume, and number of sperm in the semen were ascertained at the same time in the same animals. semen samples were obtained by penile electrostimulation ...19911907859
male mating behaviour and paternity discrimination by dna fingerprinting in a japanese macaque group. 19911937283
marked seasonal changes in response to the negative feedback action of estradiol on luteinizing hormone secretion in the female japanese monkey.the seasonal changes in response to the negative feedback action of estradiol on lh secretion were studied in two groups of ovariectomized japanese monkeys (macaca fuscata fuscata; n = 6). blood samples were collected two to three times a week, and changes in serum concentrations of lh, estradiol, and progesterone were examined. before ovariectomy (ovx), serum lh was maintained at about 320 pg/ml regardless of the season (breeding season: autumn and winter). after ovx and simultaneous treatment ...19911999150
occurrence of cathepsin d isozymes with different specificities in monkey skeletal muscle.cathepsin d was highly purified from the skeletal muscle of japanese monkey (macaca fuscata fuscata) by a procedure including affinity chromatography on concanavalin a-sepharose and pepstatin-sepharose, and then resolved into ten isozymes (a through j) by isoelectric focusing. when examined for specificity toward oxidized insulin b chain, isozyme a was highly specific and cleaved exclusively the leu15-tyr16 bond, whereas isozyme f was less specific, cleaving the leu15-tyr16 and glu13-ala14 bonds ...19912025292
diurnal changes in serum melatonin concentrations under indoor and outdoor environments and light suppression of nighttime melatonin secretion in the female japanese monkey.to examine whether artificial light with the intensity commonly used for animal experimentation can mimic natural sunlight with respect to diurnal changes in serum melatonin, and to determine the minimum light intensity required to suppress nocturnal melatonin, serum melatonin profiles were examined in groups of female japanese monkeys (macaca fuscata fuscata). under outdoor environment, light intensities at the level of the monkey's eyes varied during daytime (0900-1500 h) depending on weather ...19902082009
immunoreactive inhibin levels in peripheral blood during the breeding season in the female japanese monkey.serum levels of immunoreactive inhibin as well as fsh, lh, estradiol-17 beta, and progesterone were measured by ria in four mature female japanese monkeys (macaca fuscata fuscata) during the breeding season and subsequent transition into the nonbreeding season. during the breeding season, each monkey showed 2-6 ovulations, which were inferred from underlying endocrine events. the concentrations of serum inhibin increased during the luteal phase, but were low during the follicular phase. such cha ...19902116190
changes in circulating inhibin levels during pregnancy and early lactation in the japanese monkey.changes in immunoreactive (ir-) inhibin concentrations in serum throughout pregnancy and early lactation up to one month after parturition were characterized in 6 japanese monkeys (macaca fuscata fuscata) by a heterologous radioimmunoassay (ria) based on a bovine ria. serum levels of fsh, lh/monkey chorionic gonadotropin (mcg), estradiol-17 beta, and progesterone were also monitored for the entire period. ir-inhibin levels in the serum were low (under 0.5 ng/ml) before conception. three marked i ...19902125510
sequence of dna replication in macaca fuscata chromosomes: an outgroup for phylogenetic comparison between man and apes.the relative replication times of every band in the standardized 300 band g-band idiogram of the chromosomes of the japanese macaque are presented, and compared to the human sequence. many chromosomes thought to be homologous between macaca fuscata and man on the basis of standard chromosome banding and gene mapping show a conservation of the replication sequence. other supposed chromosomal homologies between these two species show no good correspondence, and the replication sequence data sugges ...19902323565
catecholaminergic effects on neuronal activity related to a delayed response task in monkey prefrontal cortex.1. using iontophoretic techniques, we investigated the effects of dopamine (da) and noradrenaline (na) on neuronal activity related to a delayed response (dr) task in the prefrontal cortex (pfc) of the japanese macaque monkeys. the dr task was initiated by rotation of a handle to a central zone and consisted of seven distinct time periods: an initial waiting period of 0.3 s, a precue period of 1 s (a central green lamp), a cue period of 1 s (left or right lamp), a delay period of 4 s, a go perio ...19902358882
neuropeptides in cerebral cortex of macaque monkey (macaca fuscata fuscata): regional distribution and ontogeny.the concentrations of vasoactive intestinal polypeptide, somatostatin and substance p were determined in various cerebral subdivisions of adult and foetal japanese monkeys (macaca fuscata fuscata) by specific radioimmunoassays. in adult tissues, the highest level of vasoactive intestinal polypeptide was found in the somatosensory cortex and the lowest level in the occipital cortex. a high level of somatostatin was found in the association cortex (prefrontal, parietal and temporal cortex); the lo ...19862418918
complete amino acid sequence of gamma chain of fetal hemoglobin of japanese macaque (macaca fuscata).the complete amino acid sequence of the gamma chain of japanese macaque (macaca fuscata) was deduced from sequence analysis of its tryptic peptides and a few other peptides. three amino acid residues are substituted compared to the human gamma chain, 77his (human) to 77asn (japanese macaque), 104lys to 104arg and 135thr to 135 ala. the primary structure of the gamma chain of japanese macaque is the same as that of rhesus macaque (macaca mulatta) (2) and yellow baboon (papio cynocephalus) (3). di ...19862420747
ontogeny of glutamic acid decarboxylase, tyrosine hydroxylase, choline acetyltransferase, somatostatin and substance p in monkey cerebellum.the enzyme activities of glutamic acid decarboxylase (gad), tyrosine hydroxylase (th) and choline acetyltransferase (chat) and concentrations of substance p (sp) and somatostatin were determined in the cerebellum of macaque monkey (macaca fuscata fuscata) at 3 different ages, embryonic 4 months, embryonic 5.5 months (full-term) and adult. similar graded increases in the activities of gad and th were observed during development. in contrast, chat activity was relatively high at embryonic 4 months ...19872436722
the distribution of substance p in the cerebral cortex and hippocampal formation: an immunohistochemical study in the monkey and rat.the distribution of substance p-containing fibers in the cerebral cortex and the hippocampal formation of the japanese monkey (macaca fuscata fuscata) was studied by immunohistochemistry using a monoclonal antibody raised against substance p. the results were compared with the distribution in homologous regions of the rat brain. substance p-containing fibers and cell bodies were observed in all regions of the cerebral cortex. in deep layers of the neocortex (iv-vi), substance p-immunoreactive fi ...19892468400
functional analysis of the biceps femoris muscle during locomotor behavior in some primates.in order to investigate a correlation between morphological variations of the biceps femoris muscle and its homologues in four primate species (japanese macaque, spider monkey, white-handed gibbon, and chimpanzee) and each type of species-specific locomotor behavior, i carried out both morphological and functional analyses of these muscles. the description of the level of insertion reveals interspecific variation is in the level of crural attachment, especially in species with a bicipital biceps ...19892504047
immunological and molecular comparison of simian cytomegaloviruses isolated from african green monkey (cercopithecus aethiops) and japanese macaque (macaca fuscata).simian cytomegaloviruses (cmv) isolated from african green monkeys and japanese macaques were compared serologically and genetically. twenty-three out of 31 sera from japanese, taiwan and rhesus macaques were positive for neutralizing antibodies to simian cmvs isolated from both african green monkeys and a japanese macaque. the neutralizing antibody titers of those sera were slightly higher to the isolates of african green monkeys origin than to that of japanese macaque origin. studies with anti ...19892552962
[metrical study on teeth and mandible in macaca fuscata fuscata. 2. principal component analysis].metrical investigation on teeth and mandible together was performed to understand the morphological relationship between these two components in macaca fuscata fuscata. measurements are 9 items from the mandible, 2 items from dental arch, and 8 mesiodistal diameters from teeth. correlation matrix composed of 19 items, in total, was examined in males and females, respectively. significant correlation coefficients were frequently seen among mandibular measurements and also among tooth measurements ...19892626163
[histochemical properties of secretory granules and fine structure of terminal portion in the japanese macaque labial gland].the terminal portion of the japanese macaque (macaca fuscata) labial gland was examined ultrastructurally and histochemically. the results obtained are as follows. 1) the japanese macaque, macaca fuscata has the upper and the lower labial glands, which can be described as a compound tubulo-acinar gland. 2) the terminal portion of the labial gland appears to be consisted of the mucous acini and the demilunes when examined with the light microscope. 3) the secretory granules containing in the glan ...19892637414
delayed response deficits produced by local injection of bicuculline into the dorsolateral prefrontal cortex in japanese macaque monkeys.bicuculline (10-30 micrograms, but usually 30 micrograms) was injected locally into 20 different sites in the dorsolateral prefrontal cortex (pfc) of 2 japanese macaque monkeys, while they were performing a delayed response task. the task was initiated by the rotation of a handle to a central zone by the wrist joint and consisted of seven periods: an initial waiting period of 0.3 s, a pre-cue period (central green lamp of 1.0 s), a cue period (left or right green cue of 0.3 s), a delay period of ...19892744104
comparative anatomy of the accessory ciliary ganglion in mammals.the orbits of 13 mammalian species (pig, sika deer, domestic sheep, horse, cat, fox, racoon dog, marten, rat, rabbit, crab-eating macaque, japanese macaque and man) were stained with silver nitrate and dissected under a dissecting microscope with special attention to the presence and location of the accessory ciliary ganglion. some preparations were stained with thionin and examined as whole-mounts in a transmission microscope. the accessory ciliary ganglion was present in all 13 species, althou ...19892802184
establishment of primate lymphoblastic cell lines by coculture with a simian t-cell leukemia virus-1 positive, hypoxanthine-guanine-phosphoribosyltransferase negative japanese macaque cell line.a cell line (jamh17+) resistant to 8-azaguanine was established from a human t-cell leukemia virus type 1 related virus (simian t-cell leukemia virus-1) positive japanese macaque cell line. lymphoblastic cell lines were established from the peripheral blood mononuclear cells of humans, hominoids, and several species of macaques by coculture with jamh17+ in hypoxanthine-aminopterin-thymidine medium. htlv-1 specific antigen was detected in some of the established cell lines. phenotypic analysis sh ...19882835483
effect of restricted cortical lesions on absolute thresholds and aphasia-like deficits in japanese macaques.the effect of small bilateral cortical lesions on pure-tone audiograms and on the ability to discriminate between two types of japanese macaque coo vocalizations was determined in four japanese macaques (macaca fuscata). a lesion that included the middle portion of the superior temporal gyrus of both hemispheres, that is, the primary and secondary auditory areas, resulted in a partial hearing loss as well as an inability to discriminate the vocalizations. lesions that included the ventral portio ...19892923669
ontogeny of cholecystokinin-8 and glutamic acid decarboxylase in cerebral neocortex of macaque monkey.concentration of cholecystokinin-8 and the activity of glutamic acid decarboxylase were determined in the various cerebral cortical subdivisions of japanese monkey (macaca fuscata fuscata) at three different ages (embryonic 4 months, full-term and adult). the cck-8 immunoreactive material extracted with 90% methanol from the cerebral cortex of the adult and foetal monkey were shown to be identical with synthetic cholecystokinin-8 by the criterion of co-elution on gel filtration chromatography (s ...19892924846
categorical perception of conspecific communication sounds by japanese macaques, macaca fuscata.field studies indicate that japanese macaque (macaca fuscata) communication signals vary with the social situation in which they occur [s. green, "variation of vocal pattern with social situation in the japanese monkey (macaca fuscata): a field study," in primate behavior, edited by l. a. rosenblum (academic, new york, 1975), vol. 4]. a significant acoustic property of the contact calls produced by these primates is the temporal position of a frequency peak within the vocalization, that is, an i ...19892925998
complex carbohydrate histochemistry of the surface and gastric pit epitheliums of the japanese macaque. 19862947023
mucous cell types in the major and minor salivary glands of the japanese macaque. 19862947024
aspiration pneumonia with adenovirus infection in a japanese macaque (macaca fuscata fuscata).pneumonia with aspiration of foreign bodies and adenovirus infection was identified in a wild japanese macaque which died 1 month after capture. the adenovirus infection was considered to be secondary in importance to the pneumonia.19852983149
ultrasonic assessment of pregnancy and fetal development in three species of macaque monkeys.serial ultrasonic assessments of gestational sac (gs) and fetal biparietal diameter (bpd) were performed in the japanese monkey (macaca fuscata fuscata), rhesus monkey (macaca mulatta), and crab-eating monkey (macaca fascicularis). in the japanese monkey, gs increased linearly for 3-8 weeks, whereas bpd increased in a linear-quadratic manner over 8 weeks to term. ultrasonic assessments of spontaneously aborted fetuses with bpd growth retardation and diagnosis of a pelvic chocolate cyst also were ...19883068367
novel hemoglobin components and their amino acid sequences from the crab-eating macaque (macaca fascicularis).we found two types of hemoglobin, t and r, from the crab-eating macaque and compared those to a and q previously reported. the 22 animals studied showed six different phenotypes, a, r, qa, qt, qat, and qar. analysis of the complete amino acid sequences for the alpha chains of hemoglobins q, a, t, and r revealed that amino acids at four positions, 8, 55, 71, and 78 from the n-terminal, are variable. in the alpha a chain, thr, val, gly, and gln occupy these positions, and in the alpha q chain the ...19883148734
quantitative autoradiographic localization of prostaglandin e2 binding sites in monkey diencephalon.quantitative autoradiography was performed to investigate the mapping of prostaglandin e2 binding sites in the macaca fuscata fuscata diencephalon. autoradiographs were prepared by incubation of 10-micron-thick serial frozen sections with 3h-prostaglandin e2 and were processed by using a rotating drum-scanner and a computer-assisted image-processing system with 3h-microscales as standards. the localization of prostaglandin e2 binding sites was remarkably discrete in the diencephalon. the highest ...19883164357
helminth parasites of the japanese monkey, macaca fuscata fuscata in ehime prefecture, japan. 19883221609
maternal aggression by lactating group-living japanese macaque females.this study analyzed the influence of lactation on aggression by group-living japanese macaque females. data collected during 268 hr of observation showed that lactating females exhibited much more aggression than did females in any other reproductive condition under investigation. this postpartum aggression showed distinctive features in terms of time course during lactation and target selectivity but it was not characterized by a higher intensity and severity. aggression increased progressively ...19883235061
[two cases of anomaly of the lower third molar in macaca fuscata fuscata]. 19883253577
[metrical study on teeth and mandible in macaca fuscata fuscata (japanese monkey)]. 19883253599
[neuroanatomical study of experimental tremor produced by vmt lesion in monkeys--a horseradish peroxidase study].destruction of the ventromedial tegmentum (vmt) of the midbrain in monkeys is known to produce tremors similar to those seen in parkinson's disease. to elucidate such tremorgenic mechanisms, 50% horseradish peroxidase (hrp) was injected into the vmt target region in three monkeys (macaca fuscata fuscata) and eleven adult cats. the volume injected varied between 0.05 and 0.1 microliter. the results suggest that afferent fibers to the thalamus, which passed through the vmt region, contains tractus ...19883362296
weaning variability in semi-free-ranging japanese macaques (macaca fuscata).the purpose of this research was to investigate variability in the weaning behaviours of japanese macaque (macaca fuscata) mothers and their infants and to attempt to define factors contributing to this variability. the marked level of variability in maternal weaning behaviours was unrelated to traditional sociological factors, such as the rank, parity, age and number of immature offspring of the mother, and the sex of the infant. the only variability in the weaning behaviours of the infants occ ...19873443417
pneumocystis infection in macaque monkeys: macaca fuscata fuscata and macaca fascicularis.retrospective examination of lungs from 128 monkey necropsies was attempted for pneumocystis infection using special strains, including toluidine blue-o and gomori's methenamine silver nitrate. four japanese monkeys (7.7%), macaca fuscata fuscata, and one crab-eating monkey (7.7%), macaca fascicularis, were found to have pneumocystis infection. the organism was found in young and infant animals. at the time of death, one infant and two young monkeys were debilitated and/or emaciated. pneumocysti ...19873497397
percentage of glycosylated hemoglobin and serum concentration of glucose in the blood of japanese macaques and in three exotic ruminant species.serum glucose concentrations and percentages of glycosylated hemoglobin (ghb) were determined in 16 japanese macaques and in 19 exotic ruminants (4 markhor, 5 mouflon, 10 aoudad). mean (+/- sd) serum glucose concentration and ghb percentage in the japanese macaques were 73 +/- 21.8 mg/dl and 4.7 +/- 0.82%, respectively. serum glucose concentration was considered within the normal range for this species. the mean ghb percentage was within the normal range for man, indicating that ghb may be a val ...19863752690
effect of unilateral and bilateral auditory cortex lesions on the discrimination of vocalizations by japanese macaques.ten japanese macaques were trained to discriminate between two types of japanese macaque coo vocalizations before and after auditory cortex ablation. five of the animals were tested following left unilateral ablation, whereas the other five were tested following right unilateral ablation. after postoperative testing, symmetrical lesions were made in the remaining hemisphere in two animals from each group and the effect of bilateral lesions was assessed. the animals were tested using a shock avoi ...19863783215
retroperitoneal fibromatosis and acquired immunodeficiency syndrome in macaques: epidemiologic studies.at the university of washington regional primate research center, a simian acquired immunodeficiency syndrome (saids) associated with retroperitoneal fibromatosis (rf) has been observed in 82 macaques since 1976, including 77 pigtailed macaques (macaca nemestrina), two long-tailed macaques (m. fascicularis), one japanese macaque (m. fuscata) and two rhesus macaques (m. mulatta). the syndrome is characterized by immunodeficiency accompanied by a fibroproliferative lesion, primarily affects young ...19854057939
seasonal variation in urinary 17-oxosteroids and seminal fructose in male japanese macaque monkeys (macaca fuscata fuscata). 19744406683
plasma testosterone and male dominance in a japanese macaque (macaca fuscata) troop compared with repeated measures of testosterone in laboratory males. 19744474138
male dominance and aggression in japanese macaque reproduction. 19744475646
amino acid compositions and n-terminal amino acid of all the tryptic peptides from the and polypeptide chains of adult hemoglobin of the japanese monkey (macaca fuscata fuscata). biochemical studies on hemoglobins and myoglobins. ix. 19724630784
isolation of all tryptic peptides from the aminoethylated beta polypeptide chain of adult hemoglobin from japanese monkey (macaca fuscata fuscata) and their amino acid compositions. 19694981728
isolation of all soluble tryptic peptides from the alpha polypeptide chain of adult hemoglobin from japanese monkey (macaca fuscata fuscata) and their amino acid compositions. 19694981729
the n-terminal structure of adult hemoglobin from japanese monkey (macaca fuscata fuscata) and the n-terminal amino acids of all the tryptic peptides from its alpha and beta polypeptide chains. 19694981730
the primary structure of the beta-polypeptide chain of adult hemoglobin of the japanese monkey (macaca fuscata fuscata). 19715000512
human adult t-cell leukaemia virus is distinct from a similar isolate of japanese monkeys.we have compared the structural polypeptides of an adult t-cell leukaemia (atl) virus (atlv) isolate from a japanese patient with atl with those of a similar virus derived from a japanese macaque monkey. both are distinct but related entities. their core polypeptides p19 could not be distinguished, but p24, another core polypeptide, and their envelope glycopolypeptides differ. the human virus directs the synthesis of a single intracellular glycopolypeptide, gp68, while the macaque virus specifie ...19846096497
structure and carbohydrate histochemistry of the minor salivary glands of the japanese macaque (macaca fuscata yakui). 19826214751
presence of endogenous inhibitor of aromatic l-amino acid decarboxylase in monkey serum.in the course of our studies on the developmental changes of aromatic l-amino acid decarboxylase (aadc) in the serum of japanese monkeys (macaca fuscata fuscata), we found the presence of an endogenous inhibitor of aadc in all stages of monkey life. this inhibitor inhibited the serum enzyme activity completely with l-5-hydroxytryptophan (l-5-htp) as substrate, while the activity was partially inhibited with l-dopa as substrate. the inhibitor was non-dialyzable, but it could be removed from the m ...19846333583
ambivalence in monkey mothering. infant abuse combined with maternal possessiveness.the maternal behavior of an abusive japanese macaque multiparous female was compared with that of three primiparous normal females from the same colony to evaluate the quality of the abusive mother-infant relationship. the abusive mother-infant pair scored highest on maternal warmth, protectiveness, possessiveness, and scored lowest on maternal rejectingness. the finding that the abusive mother alternated violent abuse with attentive maternal care is not consistent with the learning defect expla ...19846537968
mother-infant visual interaction in japanese macaques.patterns of visual interaction in mother-infant dyadic behavior have been reported for human and nonhuman primates, including age and gender differences among rhesus macaques. such findings are tested with data from two developmental periods (weeks 1-8 and 21-36) on japanese macaque mother-infant visual behavior. rates for look, infant facial-fixation, and eye contact are greater during the first period than in the second. in weeks 1-8, infants interact visually with their mother significantly m ...19846745500
estrogen receptors and estrogen-inducible progestin receptors in the sexual skin of the monkey.estrogen-binding macromolecules were identified in sexual skin cytosol and nuclear fractions from female japanese monkeys (macaca fuscata fuscata), by sucrose-glycerol gradient analysis and dextran-coated charcoal adsorption technique. furthermore, using the highly potent synthetic progestin, r5020 (17,21-dimethyl-19-nor-4,9-pregnadiene-3,20-dione; promegestone), progestin-binding macromolecules were detected in sexual skin cytosols from ovariectomized estrogen-primed monkeys. both cytosol compo ...19836843117
infant abuse by a wild-born group-living japanese macaque mother. 19826891392
species difference in liver microsomal and cytosolic enzymes involved in mutagenic activation of n-hydroxy-n-2-fluorenylacetamide.the mutagenic activations of n-hydroxy-n-2-fluorenylacetamide (n-oh-2-faa) by subcellular fractions of the livers of the sprague-dawley rat, c57bl mouse, hartley guinea pig, syrian golden hamster, and macaca fuscata fuscata monkey were examined for sensitivity to paraoxon, which inhibits a deacetylase but not an arylhydroxamic acid acyltransferase. the mutagenic activation by liver microsomes was almost entirely mediated by a paraoxon-sensitive enzyme in all the animals tested. in contrast, the ...19816944527
winter range utilization of a japanese macaque troop in a snowy habitat.the winter range utilization pattern of a japanese macaque troop in a snowy habitat was studied. the vegetation areas essential for subsistence were found to be relatively undisturbed mixed and deciduous forests. the concept of essential resource area (era) is defined. our comparison among three troops in the same habitat in the past and present with different population densities indicated that the per capita era is quite important in determining the range area. this implies that the population ...19827068055
cognitive development in a japanese macaque (macaca fuscata). 19827186265
the presence of progesterone receptors in the sexual skin of the monkey.r5020(17,21-dimethyl-19-nor-4,9-pregnadiene-3,20-dione)-binding components with sedimentation coefficient of 8s were detected in sexual skin cytosols from estrogen-primed ovariectomized japanese monkey (macaca fuscata fuscata). in contrast, little 8s binding was found in similar preparations from the abdominal skin. the dissociation constants and the number of binding sites of the components were 1.6 x 10(-10)m and 36 fmoles/mg cytosol protein, respectively. the 8s binding components were specif ...19807193924
acquisition of death discrimination in a japanese macaque: a preliminary study.a training method of depth discrimination in a japanese monkey was reported. using a howard-dohlman type apparatus, the monkey was required to discriminate the distance of two rods. observation distance was 785 mm and a tracking method was employed. difference thresholds measured preliminarily were 23.6 mm and 77.1 mm for binocular and monocular conditions, respectively.19817267257
postnatal changes of immunoglobulins igg, igm and iga in blood and milk of japanese macaque (macaca fuscata). 19817321297
expression of basement membrane components in the dental papilla mesenchyme of monkey tooth germs--an immunohistochemical study.the present work, which employs indirect immunoperoxidase methods, demonstrates electron microscopic localization of three major basement membrane (bm) components--type iv collagen, laminin, and heparan sulfate proteoglycan--at the early stages of odontogenesis in tooth germs of the japanese macaque (macaca fuscata). intense immunostaining for each examined component occurred at the interface between the inner enamel epithelium and the dental papilla mesenchyme. at higher magnification, immunore ...19957554936
rosette formation by plasmodium coatneyi-infected erythrocytes of the japanese macaque (macaca fuscata).we studied in vitro the spontaneous rosette formation by red blood cells of a japanese macaque infected with plasmodium coatneyi, which occurred after 30 hr of incubation. rosette formation involved 88% of parasitized red blood cells (prbcs). spontaneous rosettes were formed when the ring-stage parasites developed into late trophozoites or schizonts. a rosette usually consisted of a prbc surrounded by three or more uninfected erythrocytes. electron microscopic examination revealed that interacti ...19957573716
lipid profiles of cerebral gray matter and livers of macaque monkeys macaca fascicularis and macaca fuscata fuscata: a comparative study during development.the lipid and fatty acid profiles in cerebral gray matter and livers were studied in macaque monkeys (macaca fascicularis and m. fuscata fuscata) of different ages. in cerebral gray matter, the phosphatidylcholine/phosphatidylethanolamine (pc/pe) ratio decreased in animals more than 3 years old, while the cholesterol/lipid-phosphorus ratios and the unsaturation indices increased, as compared with those in fetuses and newborns. the level of 22:6n-3 in pe of cerebral gray matter increased up to 3 ...19957599973
basal cell tumor in a japanese macaque (macaca fuscata).a rare case of basal cell tumor of the skin in a wild-caught female japanese macaque (macaca fuscata) was studied. tumor growth, which was composed of cells resembling basal cells, was observed in the dermis and subcutis and showed a mixture of ribbon, solid, glandular, and cystic patterns. the tumor was separated from surrounding normal tissue by a compressed zone of fibrous connective tissue. the nuclei were round and hyperchromatic and possessed a single centrally located nucleolus. mitotic f ...19957604501
reproductive senescence in female japanese monkeys (macaca fuscata): age- and season-related changes in hypothalamic-pituitary-ovarian functions and fecundity rates.age- and season-related changes in gonadotropin-gonadal functions were studied in captive female japanese monkeys (macaca fuscata fuscata), with special reference to reproductive senescence. in experiment 1, a total of 57 nonlactating females at ages 3-32 yr were used. blood samples were collected for at least one breeding season (september through march), and changes in plasma concentrations of lh, estradiol, and progesterone were examined. in experiment 2, two groups of females (older females, ...19957632833
postcranial skeleton of a macaque trained for bipedal standing and walking and implications for functional adaptation.the postcranial skeleton of a japanese macaque that had been trained for bipedalism over an 11-year period was studied. considerable modifications in the hindlimb bones caused by bipedal postural and locomotor behaviour were observed. changes occurred in joint morphology, articular dimensions and shape-dependent strength of long bones, reflecting the causal relationship between function and morphology. however, the conditions under which the modifications are developed are somewhat different fro ...19957665119
microvascular pattern of the retina in the japanese monkey (macaca fuscata fuscata).the microvascular architecture of the retina in the japanese monkey was revealed using scanning electron microscopy of microvascular corrosion casts. at the optic nerve disc, the central retinal artery radiated to four primary retinal arterioles: the superior and inferior temporal arterioles and superior and inferior nasal arterioles. a dense retinal capillary network showed regional differences in density. the capillary networks observed were divided in four parts: the optic nerve disc, macula, ...19947701308
comparative mapping of the immunoglobulin c epsilon 1 gene (ighe) in five species of nonhuman primates by fluorescence in situ hybridization.the orthologous immunoglobulin c epsilon 1 gene (ighe) of the common chimpanzee, pygmy chimpanzee, orangutan, white-handed gibbon, and japanese macaque was assigned to the human chromosome 14 homologue in each species and regionally mapped by fluorescence in situ hybridization to ptr15q32 (common chimpanzee), ppa15q32 (pygmy chimpanzee), ppy15q32 (orangutan), hla17qter (white-handed gibbon), and mfu7q29 (japanese macaque). the gene localized to the terminal region of the chromosome in each speci ...19957789180
evolution of alanine:glyoxylate aminotransferase 1 peroxisomal and mitochondrial targeting. a survey of its subcellular distribution in the livers of various representatives of the classes mammalia, aves and amphibia.as part of a wider study on the molecular evolution of alanine:glyoxylate aminotransferase 1 (agt1) intracellular compartmentalization, we have determined the subcellular distribution of immunoreactive agt1, using postembedding protein a-gold immunoelectron microscopy, in the livers of various members of the classes mammalia, aves, and amphibia. as far as organellar distribution is concerned, three categories could be distinguished. in members of the first category (type i), all, or nearly all, ...19947813517
variations in fundamental frequency peak position in japanese macaque (macaca fuscata) coo calls.japanese macaques (macaca fuscata) produce coo calls whose use in various contexts is correlated with differences in the relative temporal position of the peak value of a call's fundamental frequency (green, 1975). studies have produced conflicting results about both the location of the category boundary between smooth early high and smooth late high coo subtypes and macaques' perceptual sensitivity to variations in peak position. in this study, fundamental frequency peak positions were measured ...19947924259
cervical ripening and uterine contraction induced by prostaglandin e2-gel in pregnant japanese monkeys (macaca fuscata fuscata).effects of intracervical administration of pge2-gel were studied in pregnant japanese monkeys (macaca fuscata fuscata) near term. administration of pge2-gel induced cervical ripening and an increase in maternal plasma pge2 but no change in pgf2 alpha. ultrastructural observations of the connective tissue of the cervix after pge2-gel treatment revealed a decrease in the number of collagenous fibers. these results show that intracervical administration of pge2-gel induces cervical ripening without ...19947932635
neural activities in the fronto-opercular cortex of macaque monkeys during tasting and mastication.we recorded responses from 298 units in the fronto-opercular cortex (fop) of three japanese macaque monkeys. the units were activated while animals were drinking or eating. three types of units could be defined: units with transient responses to the delivery of all the fluid into the mouth (on-type units; n = 123); units activated in association with certain oral movements, e.g., licking (mo-type units; n = 90); and units responsive specifically to a certain fluid (taste units; n = 85). in both ...19947967217
vocalizations of rhesus (macaca mulatta) and japanese (m. fuscata) macaques cross-fostered between species show evidence of only limited modification.two rhesus and two japanese macaque infants were cross-fostered between species in order to study the effects of auditory experience on vocal development. both the cross-fostered and normally raised control subjects were observed over the first 2 years of life and their vocalizations were tape-recorded. we classified 8053 calls by ear, placed each call in one of six acoustic categories, and calculated the rates at which different call-types were used in different social contexts. species differe ...19938270122
molecular anatomy of human chromosome 9: comparative mapping of the immunoglobulin processed pseudogene c epsilon 3 (ighep2) in primates.karyotypic homology in relation to human chromosome 9 (hsa 9) was studied through comparative mapping of the immunoglobulin-processed pseudogene c epsilon 3 (ighep2) in primates. ighep2, which has been mapped to 9p24.2 --> p24.1 in the human genome, was assigned to ptr 11q34 (common chimpanzee), ppa 11q34 (pygmy chimpanzee), ppy 13q16 (orangutan), hla 8qter (white-handed gibbon), hag 8qter (agile gibbon), and mfu 14q22 (japanese macaque) by fluorescence in situ hybridization. to verify the break ...19968646893
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