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decreased smooth muscle side effects with 16, 16-dimethyl-trans-delta2-pge1 methyl ester in japanese monkey (macaca fuscata fuscata).the smooth muscle stimulating activity of a new pge1 analog, 16, 16-dimethyl- trans delta2 -pge1 methyl ester (ono-802) was evaluated by simultaneously recording the emg of the uterus and intestines, along with urinary bladder pressure, and blood pressure in pregnant and non-pregnant japanese monkeys (macaca fuscata fuscata). single intravenous injections of ono-802 in increasing dosages (0.2-5 microgram/kg) were found to be 50-100 times or more effective in inducing uterine contraction than pgf ...197896494
decreased smooth muscle side effects with 16, 16-dimethyl-trans-delta2-pge1 methyl ester in japanese monkey (macaca fuscata fuscata).the smooth muscle stimulating activity of a new pge1 analog, 16, 16-dimethyl- trans delta2 -pge1 methyl ester (ono-802) was evaluated by simultaneously recording the emg of the uterus and intestines, along with urinary bladder pressure, and blood pressure in pregnant and non-pregnant japanese monkeys (macaca fuscata fuscata). single intravenous injections of ono-802 in increasing dosages (0.2-5 microgram/kg) were found to be 50-100 times or more effective in inducing uterine contraction than pgf ...197896494
scanning electron microscope observation of the seminal vesicle in the japanese monkey with special reference to intraluminal spermiophagy by macrophages.the seminal vesicle of the adult japanese monkey was observed by scanning electron microscopy. a number of spermatozoa are found scattered on the luminal surface. some of them are normal in appearance, while others disintegrated. the epithelial cells bulging slightly into the lumen are devoid of cilia, but provided with diffusely distributed microvilli. the fracture surface reveals that the epithelium of the seminal vesicle consists of columnar epithelial cells with secretory activity and occasi ...1978102301
[scanning electron microscopic studies of the normal ocular tissues. 2. scanning and transmission electron microscopic studies of the melanocytes in the iris stroma of japanese monkey (author's transl)]. 1978104561
uterine contractility and plasma levels of steroid hormones after intravaginal treatment of pregnant japanese monkeys (macaca fuscata fuscata) with 16,16-dimethyl-trans-delta2-prostaglandin e-1 methyl ester.intravaginal treatment with a pge-1 analogue (ono-802) resulted in strong uterine contractions with a high frequency which lasted for more than 3 h. when 20-50 microgram ono-802/kg were administered intravaginally 5 times every 3 h in 5 pregnant animals, vaginal bleeding started by 6 h and abortion occurred by 26 h after the initial treatment. there were no significant side effects. plasma levels of steroid hormones, especially progesterone and 20alpha-dihydroprogesterone, fluctuated initially a ...1979108397
uterine contractility and plasma levels of steroid hormones after intravaginal treatment of pregnant japanese monkeys (macaca fuscata fuscata) with 16,16-dimethyl-trans-delta2-prostaglandin e-1 methyl ester.intravaginal treatment with a pge-1 analogue (ono-802) resulted in strong uterine contractions with a high frequency which lasted for more than 3 h. when 20-50 microgram ono-802/kg were administered intravaginally 5 times every 3 h in 5 pregnant animals, vaginal bleeding started by 6 h and abortion occurred by 26 h after the initial treatment. there were no significant side effects. plasma levels of steroid hormones, especially progesterone and 20alpha-dihydroprogesterone, fluctuated initially a ...1979108397
species-specific perceptual processing of vocal sounds by monkeys.monkeys of four species were trained to discriminate between sets of natural tonal calls of japanese macaques (macaca fuscata) by the position of a frequency-inflection peak or by initial pitch. the japanese macaques consistently performed best on peak position and the other species on pitch. the results imply special strategies for perceptional processing of vocal sounds and suggest parallels with human speech perception.1979108805
cerebellar cortical atrophy in an adult japanese macaque. 1979111404
surveys of simian malaria in japan.the survey of simian malaria in japan which had been conducted since 1965 showed that no japanese monkeys (macaca fuscata fuscata and macaca fuscata yakui) were infected with malaria parasites. most interestingly, however, babesia sp. was found in 4 (4.3%) of 93 macaca fuscata yakui which had been reared in a monkey park. as for the monkeys imported from abroad, plasmodium was only found in macaca irus from southeast asia, namely, p. inui (14.1-25.0%), p. cynomologi (0.6, 3.2%) and p. coatneyi ( ...1979116437
surveys of simian malaria in japan.the survey of simian malaria in japan which had been conducted since 1965 showed that no japanese monkeys (macaca fuscata fuscata and macaca fuscata yakui) were infected with malaria parasites. most interestingly, however, babesia sp. was found in 4 (4.3%) of 93 macaca fuscata yakui which had been reared in a monkey park. as for the monkeys imported from abroad, plasmodium was only found in macaca irus from southeast asia, namely, p. inui (14.1-25.0%), p. cynomologi (0.6, 3.2%) and p. coatneyi ( ...1979116437
female aggression and male membership in troops of japanese macaques and olive baboons.a detailed comparison of macaca fuscata and papio anubis reveals that female aggression to males has an effect on male association with females in both species, but only in m. fuscata do females appear to be able to limit the number of males in their troop. it is suggested that this is the reasons why 'solitary' males are commonly reported in m. fuscata, but rare in p. anubis, and may be related ultimately to the different degrees of sexual dimorphism in the two species.1979116946
frequency of occurrence, morphology, and causes of congenital malformation of limbs in the japanese monkey. 1979119627
weights and heights of stump-tailed macaques (macaca arctoides) living in colony groups.weights and heights of adults, week-old infants, and animals of intermediate ages were obtained from colony groups of stump-tailed macaques and are compared with similar measurements of rhesus, japanese macaques, and other stump-tailed monkeys.1979120444
laparoscopic observations of follicular rupture in the japanese macaque (macaca fuscata). 1977142148
[cellular inclusions in the epithelium of the choroid plexus (biondi body) in japanese monkeys]. 1976187817
[cellular inclusions in the epithelium of the choroid plexus (biondi body) in japanese monkeys]. 1976187817
monkey vocalizations and human speech: parallels in perception?primate vocal repertoires may be classified along a continuum of discrete vs. graded signals, with the placement of a particular repertoire a result of the interplay between the species' social organization and adaptive specializations of individual signals engendered by the physical environment and their use. discussion of the different types of graded signals reveals that they may possess either transitional, ontogenetic, or internal variability. upon examination, the speech of humans is found ...1979399203
perception of conspecific vocalizations by japanese macaques. evidence for selective attention and neural lateralization.japanese macaques (macaca fuscata) and control species (vervet, pigtailed macaque, bonnet macaque) were trained for food to respond to one class of recorded fuscata vocalizations and do not respond to a second class. a measure of neural lateralization was obtained by presenting the stimuli randomly to the right or the left ear, and comparing performance in the two ears (ear advantage method). vocalizations were from steven green's field tapes. in experiment i, the two classes were green's 'smoot ...1979399204
progesterone levels in the japanese monkey (macaca fuscata fuscata) during the breeding and nonbreeding season and pregnancy.progesterone levels were determined in the peripheral blood of the japanese monkey during the menstrual cycle, breeding season, nonbreeding season, and gestation. progesterone levels averaged less than 0.3 ng/ml in the earlier follicular phase, rose to maximum values of 3.8 ng/ml approximately eight days before menses, and declined to less than 1.0 ng/ml before menstruation. progesterone levels during the nonbreeding season were comparable with those during the early follicular phase. in pregnan ...1977406405
comparative studies of coagulative and fibrinolytic faculties between the japanese monkey and the human.in the present study, the coagulative and the fibrinolytic faculties of the japanese monkey (macaca fuscata) were investigated and compared with those of the human. regarding the coagulative faculty, the plasmic fibrinogen level, prothrombin times, and partial thromboplastin times of the japanese monkey were similar to those of the human, but the antithrombin level in the monkey was higher than that in the human. regarding the fibrinolytic faculty, the simian plasminogen level was significantly ...1977406688
scanning electron microscopic observation of spermiophage cell within the lumen of the epididymal duct of the vasectomized japanese monkey (macacus fuscatus).the spermiophagic process by intraluminal macrophages in the epididymal ducts of the vasectomized japanese monkey was well visualized with scanning electron microscope. the fragments of disintegrated spermatozoa were seen in the phase enveloped in bulk by flap-like cytoplasmic extensions or in the phase ingested within the cytoplasm.1977408181
scanning electron microscopic observation of spermiophage cell within the lumen of the epididymal duct of the vasectomized japanese monkey (macacus fuscatus).the spermiophagic process by intraluminal macrophages in the epididymal ducts of the vasectomized japanese monkey was well visualized with scanning electron microscope. the fragments of disintegrated spermatozoa were seen in the phase enveloped in bulk by flap-like cytoplasmic extensions or in the phase ingested within the cytoplasm.1977408181
thermoregulation of the japanese macaque living in a snowy mountain area.a field investigation was conducted to study the thermoregulatory responses in nine japanese macaques (macaca fuscata) living in a snowy mountain area, jigoku-dani (hell valley, about 1,000 m above sea level) in shiga heights in central japan in late january 1975. at about the same time, a laboratory study was made on four japanese macaques reared in mild climate in an outdoor cage in inuyama city. in the hell valley (hv) monkeys, no significant change in metabolic rate was observed at ta betwee ...1977410988
age and sexual behavior of japanese macaques (macaca fuscata).the sexual behavior of the arashiyama west troop, a natural semi-free-ranging troop of japanese macaques, was studied during the 1973-1974 and 1974-1975 breeding seasons. the troop was transported intact from japan to its current location in south texas. there they have been free to move about in a 42.2-hectare electric fence enclosure. this report describes the relationships among age, aging, and sexual behavior. males beginning at the age of 2.5 years were observed to series-mount estrous fema ...1978416810
intra-group variations in the dental eruption sequence of macaca fuscata fuscata.the purpose of this investigation was to establish general trends of intra-group variations in the dental eruption sequence of a semi-wild troop of maca fuscata fuscata. dental impressions were taken on 128 animals of varying ages. the analysis of the dental casts revealed sexual dimorphism in sequence and timing of eruption.1977604224
dialects in japanese monkeys: vocal learning and cultural transmission of locale-specific vocal behavior?differences were detected by ear in vocalizations made during artificial feeding of japanese monkey troops at three locations. tape recording and sound spectrographic analysis confirmed a distinctive vocal pattern specific to each site and used only in the provisioning situation. the 3 different acoustic morphologies are variations on a shared tonal theme. vocal learning by macaca fuscata may have occurred separately at each site regulated by species-wide constraints on vocal production.1975813420
dialects in japanese monkeys: vocal learning and cultural transmission of locale-specific vocal behavior?differences were detected by ear in vocalizations made during artificial feeding of japanese monkey troops at three locations. tape recording and sound spectrographic analysis confirmed a distinctive vocal pattern specific to each site and used only in the provisioning situation. the 3 different acoustic morphologies are variations on a shared tonal theme. vocal learning by macaca fuscata may have occurred separately at each site regulated by species-wide constraints on vocal production.1975813420
hemoglobin izu (macaca): beta83 (ef 7) gly leads to cys. a new hemoglobin variant found in the japanese monkey (macaca fuscata).recently, ishimoto, kuwata and shotake reported a polymerizing hemoglobin found in japanese monkey (macaca fuscata) (j. anthropol. soc. nippon 83, 233-243 (1975)). they separated the variant hemoglobin by gel filtration and from finger print results and from the fact that beta-mercaptoethanol dissociates the polymer deduced the substitution of an amino acid(s) by cysteine in the betat10 peptide. we have purified the variant hemoglobin by ion-exchange chromatography using carboxymethyl cellulose ...1977406934
the carbohydrate moiety of japanese monkey pepsinogens. its composition and site of attachment to protein. 1977402137
seasonal changes of plasma estradiol and progesterone in the japanese monkey (macaca fuscata fuscata).the plasma levels of estradiol and progesterone in 5 mature female japanese monkeys (macaca fuscata fuscata) throughout a breeding and nonbreeding season were measured by radioimmunoassay. as the breeding season approached, plasma estradiol levels started to increase and a few elevations were detected. however, neither a plasma progesterone rise nor menstrual bleeding was seen. menstrual bleeding began in december and recurred regularly 4 or 5 times at 4 week intervals until april. during this p ...1977401026
seasonal changes of plasma estradiol and progesterone in the japanese monkey (macaca fuscata fuscata).the plasma levels of estradiol and progesterone in 5 mature female japanese monkeys (macaca fuscata fuscata) throughout a breeding and nonbreeding season were measured by radioimmunoassay. as the breeding season approached, plasma estradiol levels started to increase and a few elevations were detected. however, neither a plasma progesterone rise nor menstrual bleeding was seen. menstrual bleeding began in december and recurred regularly 4 or 5 times at 4 week intervals until april. during this p ...1977401026
sem observation of the contractile cells of japanese monkey seminiferous tubules treated with hcl-collagenase. 1979231080
a study of roles in the arashiyama west troop of japanese monkey (macaca fuscata). 1976824098
the effect of prostaglandins on the electromyogram and motility of the monkey uterus and oviduct in late pregnancy and postpartum.the electromyogram of the monkey (macaca fuscata fuscata and macaca mulatta) uterus in labor presents spike bursts which accompany the rising intrauterine pressure. asynchronous localized electrical activity develops into synchronous activity during the course of labor. the early postpartum uterus shows an irregular pattern or continuous small bursts of spikes. during labor it responds markedly to prostaglandins (pgs); this declines in postpartum. direct intrauterine injection of pgf2a is effect ...1977875007
a spontaneous neuropathy of free-ranging japanese macaques.thirteen cases of a spontaneous neuropathy were observed among 150 free-ranging japanese snow monkeys (macaca fuscata). necropsy of 4 individuals revealed lesions in the peripheral and central nervous systems. pathologic changes were associated with ingestion of coyotillo berries (karwinskia humboldtiana).19751134041
a comparison of thermoregulatory responses in the japanese macaque (macca fuscata) and the crab-eating macaque (macaca irus) during cold exposure.thermoregulatory responses in four male adult japanese macaques and four male adult crab-eating macaques, weighing 6-12 kg and 6.2-8 kg, respectively, were compared at ambient temperatures (ta) ranging from 5 degrees c to 25 degrees c. the average values +/- s.e. for some physiological measurements made at ta of 25 degrees c in the japanese macaque and the crab-eating macaque, respectively, were as follows: resting metabolic rate; 47.6 +/- 5.0 and 42.5 +/- 1.7 w/m2; tissue conductance; 11.9 +/- ...19751152303
grooming and consort partner selection in a troop of japanese monkeys (macaca fuscata).the arashiyama west troop of macaca fuscata consists of 150 monkeys transported from kyoto, japan, in february 1972 to their present location near laredo, texas. at this site the animals range over 108 acres and during the study period were only minimally provisioned and disturbed. in the report of a 3-year study of consort partner selection it was suggested that yearlong social bonds within the troop appeared to be distinct from consort bonds formed during mating season. like sade, we consider ...1979115445
grooming and consort partner selection in a troop of japanese monkeys (macaca fuscata).the arashiyama west troop of macaca fuscata consists of 150 monkeys transported from kyoto, japan, in february 1972 to their present location near laredo, texas. at this site the animals range over 108 acres and during the study period were only minimally provisioned and disturbed. in the report of a 3-year study of consort partner selection it was suggested that yearlong social bonds within the troop appeared to be distinct from consort bonds formed during mating season. like sade, we consider ...1979115445
[neuropathological studies on aged japanese monkeys (macaca fuscata): on cerebral vascular changes of aged monkeys (author's transl)]. 1978104071
influences of female partner preference on potential reproductive outcome in japanese macaques.the immediate effects of female partner preference on male mating behaviors and its potential influence on male reproductive success and conception in the japanese macaque (macaca fuscata) were analyzed. although male dominance interactions probably led to low-ranking males having more single-day consortships and high-ranking males more multi-day consortships, dominant males were unable to prevent females from mating with preferred subordinate males. ultimately, there was no marked difference in ...19921297630
[neuropathological studies on aged japanese monkeys (macaca fuscata): on cerebral vascular changes of aged monkeys (author's transl)]. 1978104071
monkey pepsinogens and pepsins. iii. carbohydrate moiety of japanese monkey pepsinogens and the amino acid sequence around the site of its attachment to protein.purified japanese monkey pepsinogens i and ii contain carbohydrate as a part of the enzyme molecule. by gel filtration on sephadex g-100, chromatography on de-32 cellulose, and polyacrylamide disc gel electrophoresis, the carbohydrate moiety could not be separated from the enzyme protein, and the content did not decrease on repeated chromatography. glycopeptides were obtained by successive digestion of pepsinogens with thermolysin and aminopeptidases and isolated by chromatography on sephadex g- ...1978101535
neural lateralization of species-specific vocalizations by japanese macaques (macaca fuscata).five japanese macaques and five other old world monkeys were trained to discriminate among field-recorded japanese macaque vocalizations. one task required discrimination of a communicatively relevant acoustic feature ("peak"), and a second required discrimination of an orthogonal feature of the same vocalizations ("pitch"). the japanese animals more proficiently discriminated the peak feature when stimuli were presented to the right ear (primarily left cerebral hemisphere), as opposed to the le ...197899817
horseradish peroxidase-labelled cells in cervical sympathetic and trigeminal nervous systems after injection of hrp into tooth pulp in monkeys and tree shrews (a preliminary report).the neurons that project to the tooth pulp were examined by the hrp-retrograde transport technique, using 4 monkeys (3 japanese monkeys and a crab-eating monkey) and 6 tree shrews. the present investigation showed that a large number of sympathetic cervical ganglion neurons, small and medium in size, project to the molar teeth from the superior, middle and inferior ganglia and a small number of gasserian gangilon neurons (small in size) to the molar teeth ipsilaterally.197987281
horseradish peroxidase-labelled cells in cervical sympathetic and trigeminal nervous systems after injection of hrp into tooth pulp in monkeys and tree shrews (a preliminary report).the neurons that project to the tooth pulp were examined by the hrp-retrograde transport technique, using 4 monkeys (3 japanese monkeys and a crab-eating monkey) and 6 tree shrews. the present investigation showed that a large number of sympathetic cervical ganglion neurons, small and medium in size, project to the molar teeth from the superior, middle and inferior ganglia and a small number of gasserian gangilon neurons (small in size) to the molar teeth ipsilaterally.197987281
the structure and function of acid proteases. viii. purification and characterization of cathepsins d from japanese monkey lung.two kinds of cathepsin d were found in japanese monkey lung and were named cathepsins d-i and d-ii. cathepsin d-i was partially purified by ammonium sulfate fractionation and deae-cellulose column chromatography. it had properties common to other ordinary cathepsins d in terms of the elution position from a deae-cellulose column at ph 8.0, the ph-dependence of activity toward acid-denatured hemoglobin, and the molecular weight of 35,000 as determined by sephadex g-100 gel filtration. on the othe ...197824623
formaldehyde formation as a metabolite of methoxyflurane.the production of formaldehyde as a metabolite of enzymatic biotransformation of methoxyflurane was observed in vitro in hepatic microsomal preparations derived from japanese monkeys, rabbits and wistar strain rats. production rates of formaldehyde were 0.80-2.50 n moles/mg protein/min in the induced group which was pretreated with phenobarbitone, and 0.15-0.68 n moles/mg protein/min in the non-induced group. this reaction needed the presence of nadph and oxygen. formaldehyde production was almo ...197716507
immunohistochemical and enzymehistochemical studies of peptidergic, aminergic and cholinergic innervation of the lacrimal gland of the monkey (macaca fuscata).the distribution of nerve fibers containing peptides which include calcitonin gene-related peptide (cgrp), substance p (sp), neuropeptide y (npy) and vasoactive intestinal polypeptide (vip) and enzymes of tyrosine hydroxylase (th) and acetylcholinesterase (ache) in the lacrimal gland of the monkey (macaca fuscata) was studied using immunohistochemical and enzymehistochemical methods. we also examined the trigeminal ganglion (tg) and superior cervical ganglion (scg) using the same methods. all pe ...19921375236
responses of isolated japanese monkey tracheal muscle to allergic mediators.the responsiveness of isolated japanese monkey (macaca fuscata) tracheal muscle to antigen, carbachol, histamine, leukotriene c4 (ltc4), u-46619 and substance p (sp) was compared to that of isolated human trachea. weak but persistent contraction was observed after the addition of antigen to isolated japanese monkey tracheal muscle passively sensitized with monkey serum containing ige antibody against japanese cedar (cryptomeria japonica) antigen. unlike monkey tracheal muscle, a fair amount of c ...19921378043
formaldehyde formation as a metabolite of methoxyflurane.the production of formaldehyde as a metabolite of enzymatic biotransformation of methoxyflurane was observed in vitro in hepatic microsomal preparations derived from japanese monkeys, rabbits and wistar strain rats. production rates of formaldehyde were 0.80-2.50 n moles/mg protein/min in the induced group which was pretreated with phenobarbitone, and 0.15-0.68 n moles/mg protein/min in the non-induced group. this reaction needed the presence of nadph and oxygen. formaldehyde production was almo ...197716507
the structure and function of acid proteases. vii. distribution and some properties of acid proteases in monkey tissues.1. the distribution of acid protease activity in various tissues of japanese monkey (macaca fuscata fuscata) was investigated with hemoglobin as a substrate at ph 3.0. the activity per protein weight in crude extracts was highest in spleen and lung, and decreased in the order: spleen, lung greater than kidney, testis greater than brain greater than liver, placenta greater than thyroid gland, muscle. the activity in crude muscle extract was about one-tenth those of spleen and lung. the activity p ...197714947
pepsinogen c and pepsin c from gastric mucosa of japanese monkey. purification and characterization.a new pepsinogen component, pepsinogen c, was purified from the gastric mucosa of japanese monkey. the chromatographic behavior of this component on de-32 cellulose was coincident with that of pepsinogen iii-2 previously reported (1), and final purification was performed by large-scale polyacrylamide disc gel electrophoresis. the molecular weight was 35,000 as determined by gel filtration. the ratios of glutamic acid to aspartic acid and of leucine to isoleucine were higher than those of other j ...197612157
oxygen equilibrium characteristics of adult and fetal hemoglobin of japanese monkey (macaca fuscata).adult hemoglobin and fetal hemoglobin were obtained from japanese monkey (macaca fuscata) and their oxygen equilibrium characteristics were studied. (1) the oxygen affinity of fetal hemoglobin was higher than that of adult hemoglobin both in the presence and absence of 2,3-diphosphoglycerate. the presence of diphosphoglycerate lowers the oxygen affinity of adult hemoglobin much greater than does that of hbf and the diphosphoglycerate levels of red cells of adult and newborn monkeys are about the ...197610977
effect of t-shaped progesterone-releasing system on contraceptive efficacy and menstrual cycle regularity in japanese monkeys.twenty-seven sexually mature japanese monkeys (macaca fuscata fuscata) weighing 6 to 8 kg were used to evaluate and characterize the local and systemic effects of a t-shaped progesterone-releasing system (uts) following transabdominal insertion into the uterus. none of five experimental animals conceived, while four of five sham-operated control animals and all intact animals conceived. the general physical appearance, behavior, and clinical blood chemical titer of animals receiving the uts were ...1976819310
effect of t-shaped progesterone-releasing system on contraceptive efficacy and menstrual cycle regularity in japanese monkeys.twenty-seven sexually mature japanese monkeys (macaca fuscata fuscata) weighing 6 to 8 kg were used to evaluate and characterize the local and systemic effects of a t-shaped progesterone-releasing system (uts) following transabdominal insertion into the uterus. none of five experimental animals conceived, while four of five sham-operated control animals and all intact animals conceived. the general physical appearance, behavior, and clinical blood chemical titer of animals receiving the uts were ...1976819310
[on corpora amyrlacea in the central nervous system of macaca fuscata fuscata (author's transl)]. 1975814566
ultrastructure research of the endocardial endothelium of monkeys.the surface structure of the endocardial endothelium of normal monkeys (macaca fuscata and m. irus) was studied using scanning and transmission electron microscopy. the endocardium was covered by a layer of endothelial cells, each of which was recognized by the presence of nuclear bulge and marginal folds. the free cell surface was covered by a number of microvilli. the size of the endothelial cell and its surface morphology varied considerably in the different portions of the heart. the endothe ...1975812453
scanning electron microscopy of epididymal ducts in the japanese monkey (macacus fuscatus) with special reference to the architectural analysis of stereocilia.the luminal surface of the initial segment of the epididymal duct in the japanese monkey was observed under a field emission type scanning electron microscope. the long, slender stereocilia projecting from the apical surface of the columnar cells were found to be closely arranged in a funnel-like form opening to the lumen. the funnels formed by stereocilia were also confirmed by observation of thin sections cut from the same specimen used for scanning electron microscopy and their bottom was loc ...1975810114
[changes in retinal blood flow volume in experimental retinal vein compression].the authors quantitated the retinal blood flow volume during and immediately after experimental compression of the temporal retinal vein in 5 macaca fuscata monkey eyes. the hydrogen clearance method was used to quantitate the retinal blood flow volume. after placing a microelectrode on the retinal surface, we measured the blood flow volume 4 times at a 15-minute interval. this value served as a baseline for the experiments. next we compressed the temporal retinal vein near the disc with a 25-ga ...19921442348
kin selection in the japanese monkey. 1977560939
pepsinogens and pepsins from gastric mucosa of japanese monkey. purification and characterization.five pepsinogens were purified from gastric mucosa of japanese monkey by deae-cellulose column chromatography and sephadex g-100 gel filtration. each was shown to be homogeneous by polyacrylamide disc gel electrophoresis. they were designated as pepsinogens i, ii, iii-1, iii-2, and iii-3, respectively, based on the elution profile on deae-cellulose chromatography. the molecular weights of pepsinogens i and ii were 48,000 and 43,000, respectively, and those of the other three were 40,000. each pe ...1976820694
effects of castration and androgen-substitution on the morphology of the epididymal epithelium of the japanese monkey, macacus fuscatus, as revealed by scanning electron microscopy.the caput epididymidis from castrated and androgen-supplemented, castrated japanese monkeys was observed with the scanning electron microscope. the experimental findings were compared with the normal structures in control animals. the epididymal lumen of control animals was lined by a tall, pseudostratified columnar epithelium possessing long, slender stereocilia which were densely arranged in a tuft-like form. after castration, the epididymal epithelium was decreased in height to one-fifth of c ...1976822942
monkey performance: the development of bipedalism in trained japanese monkeys.a series of studies collaborated by the suo-sarumawashi (japanese monkey performance) revealed the potential for bipedalism in japanese monkey. the long-term training which aimed at stable upright posture introduced marked lumbar lordosis in monkeys. this feature is comparable to the humans' condition not only morphologically, but also functionally. the developed lordosis was retained even in normal pronograde posture of the monkeys. bone remodeling in the postcranial skeleton also evidenced fun ...19921523956
monkey performance: the development of bipedalism in trained japanese monkeys.a series of studies collaborated by the suo-sarumawashi (japanese monkey performance) revealed the potential for bipedalism in japanese monkey. the long-term training which aimed at stable upright posture introduced marked lumbar lordosis in monkeys. this feature is comparable to the humans' condition not only morphologically, but also functionally. the developed lordosis was retained even in normal pronograde posture of the monkeys. bone remodeling in the postcranial skeleton also evidenced fun ...19921523956
effects of castration and androgen-substitution on the morphology of the epididymal epithelium of the japanese monkey, macacus fuscatus, as revealed by scanning electron microscopy.the caput epididymidis from castrated and androgen-supplemented, castrated japanese monkeys was observed with the scanning electron microscope. the experimental findings were compared with the normal structures in control animals. the epididymal lumen of control animals was lined by a tall, pseudostratified columnar epithelium possessing long, slender stereocilia which were densely arranged in a tuft-like form. after castration, the epididymal epithelium was decreased in height to one-fifth of c ...1976822942
hindlimb proportions, allometry, and biomechanics in old world monkeys (primates, cercopithecidae).the traditional focus on morphological rather than mechanical units has obscured some significant functional differences in the hindlimbs of primates. this paper examines the allometric and biomechanical basis for some distinctive proportional differences among pairs of morphological units in the hindlimb, and especially the foot, of cercopithecid primates. five major conclusions are reached. first, many hindlimb dimensions scale allometrically with body mass to maintain mechanical similarity wi ...19921543245
effect of acid etching on the dental pulp in adhesive composite restorations.pulpal response to marginal enamel etching or both enamel and dentine etching with 37% phosphoric acid for adhesive composite restorations was studied in the teeth of the japanese monkey (macaca fuscata). dentine etching irritated the pulp and caused moderate to severe initial changes along the odontoblastic layer at 3 days. when no bacteria were present along the cavity walls, the subsequent pulpal reactions at 30 and 90 days decreased with time and large amounts of irritation dentine were form ...19921563819
effect of clipping the coat of the japanese macaque (macaca fuscata) on the thermoregulatory responses.effect of clipping the coat of the japanese macaque on thermoregulatory responses was studied. heat production was significantly increased in clipped animals in comparison without clipped coats at ambient temperatures ranging from 5 to 25 degrees c. at ambient temperatures of 5, 15, and 25 degrees c tissue thermal conductance and cooling constant were significantly higher in clipped animals. clipped animals could maintain thermal equilibrium at an ambient temperature of 5 degrees c, conpensating ...1976823355
[the artificial fecundation in japanese monkeys (macaca fuscata) by induced ovulation and artificial insemination in nonmating season].induced ovulation trials by pmsg-hcg administration were conducted in eleven female japanese monkeys showing neither bleeding nor ovulation in nonmating season. the ovulation was confirmed by the laparoscopic observation in nine of the 11 females. artificial inseminations were performed in these 9 females by the injection of semen collected by the penile electrode approach. the semen was injected into the uterine cervix in 6 females or the uterine cavity in 3 females. a gestational sac was confi ...19921577088
[the artificial fecundation in japanese monkeys (macaca fuscata) by induced ovulation and artificial insemination in nonmating season].induced ovulation trials by pmsg-hcg administration were conducted in eleven female japanese monkeys showing neither bleeding nor ovulation in nonmating season. the ovulation was confirmed by the laparoscopic observation in nine of the 11 females. artificial inseminations were performed in these 9 females by the injection of semen collected by the penile electrode approach. the semen was injected into the uterine cervix in 6 females or the uterine cavity in 3 females. a gestational sac was confi ...19921577088
cyclic changes in the charge profile of lh in anterior pituitary glands of adult female japanese monkeys (macaca fuscata). 19921297853
formant frequency discrimination by japanese macaques (macaca fuscata).these studies investigated formant frequency discrimination by japanese macaques (macaca fuscata) using an ax discrimination procedure and techniques of operant conditioning. nonhuman subjects were significantly more sensitive to increments in the center frequency of either the first (f1) or second (f2) formant of single-formant complexes than to corresponding pure-tone frequency shifts. furthermore, difference limens (dls) for multiformant signals were not significantly different than those for ...19921619126
formant frequency discrimination by japanese macaques (macaca fuscata).these studies investigated formant frequency discrimination by japanese macaques (macaca fuscata) using an ax discrimination procedure and techniques of operant conditioning. nonhuman subjects were significantly more sensitive to increments in the center frequency of either the first (f1) or second (f2) formant of single-formant complexes than to corresponding pure-tone frequency shifts. furthermore, difference limens (dls) for multiformant signals were not significantly different than those for ...19921619126
histological and histochemical investigations on japanese lizard esophagus.the authors previously investigated the bottle-shaped glands distributed in the lamina propria mucosae of the japanese lizard and gecko. we made two sets of sections of the japanese lizard at that time. the numerical values of the physical dimensions of the two individuals were as given table 1, showing that no. 2 was slightly smaller. moreover we found very unusual tissue in the lower portion of the esophagus of no. 2. therefore we excluded this individual from the preceding investigations. how ...19921620528
cyclic changes in the charge profile of lh in anterior pituitary glands of adult female japanese monkeys (macaca fuscata). 19921297853
measurement of serum ige antibodies against japanese cedar pollen (cryptomeria japonica) in japanese monkeys (macaca fuscata) with pollinosis.ige antibodies against allergens of japanese cedar (cryptomeria japonica, cj) pollen in the serum of seven japanese monkeys (macaca fuscata) with pollinosis were measured by fluorometric indirect enzyme-linked immunosorbent assay (elisa). all of the monkeys were found to have specific ige to the crude pollen antigen. the specific ige levels were well correlated with those determined by the pharmacia cap system. ige antibodies were then assayed with two kinds of purified allergens (cry j i and cr ...19921297854
measurement of serum ige antibodies against japanese cedar pollen (cryptomeria japonica) in japanese monkeys (macaca fuscata) with pollinosis.ige antibodies against allergens of japanese cedar (cryptomeria japonica, cj) pollen in the serum of seven japanese monkeys (macaca fuscata) with pollinosis were measured by fluorometric indirect enzyme-linked immunosorbent assay (elisa). all of the monkeys were found to have specific ige to the crude pollen antigen. the specific ige levels were well correlated with those determined by the pharmacia cap system. ige antibodies were then assayed with two kinds of purified allergens (cry j i and cr ...19921297854
dna polymorphisms in the psi beta 1- and beta-globin gene regions in asian macaques.dna polymorphisms in the psi beta 1-beta-globin gene region in nine asian macaques (macaca fuscata, m. mulatta, m. nemestrina, m. cyclopis, m. fascicularis, m. arctoides, m. radiata, m. maura, and m. assamensis) were examined using several restriction endonucleasese and the human psi beta 1, delta ivs2, and beta ivs2 probes. the bamhi site 3' to the beta-globin gene was polymorphic in m. fuscata and m. mulatta, while the hincii site and the ecori site in the psi beta 1-globin gene region was hig ...19911677560
dna polymorphisms in the epsilon- and gamma-globin gene regions in asian macaques.dna polymorphisms in the epsilon- and gamma-globin gene regions in nine asian macaques (macaca fuscata, m. mulatta, m. nemestrina, m. cyclopis, m. fascicularis, m. arctoides, m. radiata, m. maura, and m. assamensis) were examined using several different restriction endonucleases and the human epsilon and gamma ivs2 probes. m. fuscata and m. mulatta had highly polymorphic sites (bglii and hincii, respectively) in the epsilon-globin gene region. the bamhi site in the gamma-globin gene region was h ...19911677561
heteroplasmy and polymorphism in the major noncoding region of mitochondrial dna in japanese monkeys: association with tandemly repeated sequences.we have sequenced the major noncoding region of mitochondrial dna (mtdna) of four japanese monkeys and have found length polymorphism in the sequenced region. the length polymorphism resulted from two tandem duplications of 160-bp sequences which contained the conserved sequence blocks 2 and 3 and the light-strand transcription-promoter region. we also found polymorphisms in this mtdna region among 100 japanese monkeys from 12 localities, 90 of which were analyzed using dna amplified through the ...19911681409
heteroplasmy and polymorphism in the major noncoding region of mitochondrial dna in japanese monkeys: association with tandemly repeated sequences.we have sequenced the major noncoding region of mitochondrial dna (mtdna) of four japanese monkeys and have found length polymorphism in the sequenced region. the length polymorphism resulted from two tandem duplications of 160-bp sequences which contained the conserved sequence blocks 2 and 3 and the light-strand transcription-promoter region. we also found polymorphisms in this mtdna region among 100 japanese monkeys from 12 localities, 90 of which were analyzed using dna amplified through the ...19911681409
distribution of somatostatin-immunoreactive cell bodies and fibers in the neocortex of macaca fuscata.the distribution of somatostatin-immunoreactive cell bodies and processes was studied in the cerebral cortex of the macaque monkey (macaca fuscata), by applying an immunohistochemical technique with a monoclonal antibody raised against somatostatin tetradecapeptide. many somatostatin-immunoreactive cell bodies and processes were observed in all regions of the cerebral cortex, i.e., frontal, parietal, temporal, insular, occipital, and cingulate cortices, and also in the underlying white matter. t ...19911686672
single retinal ganglion cells sending axon collaterals to the bilateral superior colliculi: a fluorescent retrograde double-labeling study in the japanese monkey (macaca fuscata).single retinal ganglion cells projecting bilaterally to the superior colliculi (sc) by way of axon collaterals were revealed in the japanese monkey (macaca fuscata). after injecting fast blue into the sc on one side and diamidino yellow into the sc on the opposite side, some retinal ganglion cells were double-labeled with both tracers. most of them were large cells (more than 25 microns in diameter), and were localized in a narrow strip around the vertical meridian of the retina on each side. th ...19921477729
ribosomal ribonucleic acid (rrna) gene typing for species identification.deoxyribonucleic acid (dna) typing of ribosomal ribonucleic acid (rrna) genes was performed with a polymerase chain reaction (pcr) assay for species identification. a variable region of the 28s ribosomal rna gene was amplified with primers complementary to flanking sequences phylogenetically well conserved. the products of twelve animal dnas (human, japanese monkey, dog, cattle, pig, cat, rabbit, mouse, rat, chicken, frog, and fish) were separated by polyacrylamide gel electrophoresis, each reve ...19921500890
mechanism underlying the response to vasodilator nerve stimulation in isolated dog and monkey cerebral arteries.relaxant responses to transmural electrical stimulation and nicotine of cerebral artery strips obtained from dogs and japanese monkeys were abolished by tetrodotoxin and hexamethonium, respectively, and suppressed by treatment with ng-monomethyl-l-arginine (l-nmma), a nitric oxide (no) synthesis inhibitor. the inhibitory effect was prevented and reversed by l-arginine but not by d-arginine. the relaxations suppressed by l-nmma were not increased by exogenously applied no. endothelium denudation ...19901700632
mechanism underlying the response to vasodilator nerve stimulation in isolated dog and monkey cerebral arteries.relaxant responses to transmural electrical stimulation and nicotine of cerebral artery strips obtained from dogs and japanese monkeys were abolished by tetrodotoxin and hexamethonium, respectively, and suppressed by treatment with ng-monomethyl-l-arginine (l-nmma), a nitric oxide (no) synthesis inhibitor. the inhibitory effect was prevented and reversed by l-arginine but not by d-arginine. the relaxations suppressed by l-nmma were not increased by exogenously applied no. endothelium denudation ...19901700632
[proceedings: anatomical studies of the ano-rectum of japanese monkeys and dogs]. 19751232408
[proceedings: anatomical studies of the ano-rectum of japanese monkeys and dogs]. 19751232408
species differences in the coexistence of 5-hydroxytryptamine and substance p in presynaptic boutons in the cervical ventral horn.substance p (sp)- and 5-hydroxytryptamine (5-ht)-containing presynaptic boutons in the cervical ventral horn were studied in chicken, hamster, rat and monkey spinal cords, using pap and protein a-gold double-labeling techniques in conjunction with monoclonal antibodies. in the chicken, the pap method demonstrated that sp-immunoreactive boutons contained large spherical dense-cored vesicles (dcvs) whereas 5-ht-immunoreactive boutons displayed both elongated and spherical dcvs. using the protein a ...19911715239
detection of simian t-lymphotropic virus type i using the polymerase chain reaction.to develop the polymerase chain reaction (pcr) for the detection of simian t-lymphotropic virus type i (stlv-i) infection, cell lines or peripheral-blood mononuclear cells (pbmc) from 2 non-human primate species [african green monkeys (agm), cercopithecus aethiops; baboon, papio cynocephalus] were evaluated for their stlv-i status using oligonucleotide primer pairs and probes specific for the tax and pol gene regions of the closely related human t-lymphotropic virus type i (htlv-i). these pcr re ...19921312066
cytochrome oxidase staining facilitates unequivocal visualization of the primary gustatory area in the fronto-operculo-insular cortex of macaque monkeys.fronto-opercular and insular cortices of japanese macaques were histochemically stained for cytochrome oxidase activity. the laminated pattern of enzyme activity differed in the different cytoarchitectonic areas. area g, the presumed primary gustatory area, as well as area 3 were prominent because the third stripe, corresponding to the termination layers of the specific thalamocortical projection in these areas was very dark and thick in comparison with that from the neighboring areas. this appr ...19911721111
fine structure of the dorsal lingual epithelium of the japanese monkey macaca fuscata fuscata.filiform papillae, which were densely distributed all over the dorsal surface of the lingual body, were crown-shaped, with a central, circular area that sloped in the anterior direction and several branches that surrounded it in a semicircle from the back of the central area. dome-shaped, fungiform papillae were scattered among these filiform papillae. at the posterior end of the lingual body, there were four circumvallate papillae. prominent microridges and elevated intercellular borders were w ...19921382355
species-specific epitopes exist on the cytoplasmic amino-terminal domain of erythrocyte band 3 protein.monoclonal antibodies (p3-9h, p3-1f, p3-2h, p3-4a, and p3-4c) to human erythrocyte band 3 were produced using human erythrocyte membranes as the immunogen. all epitopes defined by these antibodies were found on the amino-terminal cytoplasmic domain of erythrocyte band 3. the antibodies crossreacted variously with erythrocyte band 3 of primates (chimpanzee, orangutan, rhesus monkey, japanese monkey, spider monkey, and capuchin monkey) in enzyme-linked immunosorbent assay. p3-9h did not crossreact ...19921383196
functional significance of female japanese macaque copulatory calls. 19921398344
hyperlipidemia and atherosclerosis in experimental insulinopenic diabetic monkeys.chronic insulinopenic diabetes was induced by i.v. streptozotocin in the non-human primate macaca fuscata. five diabetic monkeys were kept for 8-19 months and nine for 24-48 months without any insulin treatment. hyperglycemia (241 +/- 22 mg/dl, m +/- se less than or equal to 1 year) progressed to 376 +/- 34 mg/dl (greater than 2 years) and ketosis to 3.5 mm (greater than 2 years) during the course of diabetes; this was roughly inversely proportional to hypoinsulinemia (3.4 microu/ml, 2 years). s ...19921425136
structure and distribution of the lymphatic vessels in the parietal pleura of the monkey as studied by enzyme-histochemistry and by light and electron microscopy.the entire distribution of lymphatics in whole mount preparations of the japanese monkey was studied using the enzyme-histochemical technique reported by kato et al. (1990, 1991). in this staining, the lymphatic endothelium was colored dark brown by its positive 5'-nucleotidase activity, while most blood vessels (especially arterioles) were colored blue due to their positive alkaline phosphatase reaction. the whole mount preparations of the pleura treated enzyme-histochemically clearly indicated ...19921295550
an autoradiographic study of cortical projections from motor thalamic nuclei in the macaque monkey.the special areal and laminar distributions of cortical afferent connections from various thalamic nuclei in the monkey (macaca fuscata) were studied by using the anterograde axonal transport technique of autoradiography. the following findings were obtained. the superficial thalamocortical (t-c) projections, terminating in the (superficial half of) cortical layer i, arise mainly from the nucleus ventralis anterior, pars principalis (vapc) and nucleus ventralis lateralis, pars oralis (vlo), and ...19921374871
a motor area rostral to the supplementary motor area (presupplementary motor area) in the monkey: neuronal activity during a learned motor task.1. the rostromesial agranular frontal cortex of macaque monkey (macaca fuscata), traditionally defined as the supplementary motor area (sma), was studied using various physiological techniques to delineate two different areas rostrocaudally. 2. field and unitary responses to electrical stimulation of the primary motor cortex were distinct in the caudal part, but minimal or absent in the rostral part. intracortical microstimulation readily evoked limb or orofacial movements in the caudal part, bu ...19921432040
auditory evoked potentials in the japanese monkey.auditory sensitivity based on auditory brain stem response (abr), whole nerve action potential (ap), and cochlear microphonics (cm) to tone bursts of 0.5-8 khz were compared with behavioral audiometry in the japanese monkeys. although sensitivity loss at 4-6 khz was observed in these potentials, an increase in sensitivity at 8 khz was obtained only in the abr. thus the sensitivity loss at 4-6 khz originates at the peripheral system and the increased sensitivity at 8 khz originates at the central ...19911757970
auditory evoked potentials in the japanese monkey.auditory sensitivity based on auditory brain stem response (abr), whole nerve action potential (ap), and cochlear microphonics (cm) to tone bursts of 0.5-8 khz were compared with behavioral audiometry in the japanese monkeys. although sensitivity loss at 4-6 khz was observed in these potentials, an increase in sensitivity at 8 khz was obtained only in the abr. thus the sensitivity loss at 4-6 khz originates at the peripheral system and the increased sensitivity at 8 khz originates at the central ...19911757970
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