Publications

TitleAbstractYear
Filter
PMID
Filter
junctions between interstitial cells of the renal medulla: a freeze-fracture study.cell junctions between interstitial cells of the renal medulla were studied in freeze-fracture replicas of kidneys from rat, rabbit, hamster and the tree-shrew tupaia belangeri. in all species studied a composite type of intercellular junction was found comprising elements of tight junctions and irregular gap junctions of highly variable size and shape. the number of these junctions increased towards the tip of the papilla. our findings suggest that the composite junctions observed play a role i ...1979574802
converging projections from the mediodorsal thalamic nucleus and mesencephalic dopaminergic neurons to the neocortex in three species.previous studies in the rat have shown that the neocortical dopaminergic afferents, originating in the mesencephalon, terminate in those areas of the frontal lobe which receive projections from the mediodorsal thalamic nucleus i.e., the prefrontal cortex. in order to clarify whether this overlap is accidental for the rat or a consistent feature of several species we have compared the projection areas of the ventral tegmental area and the mediodorsal thalamic nucleus in three species, rat, opossu ...1978649789
amino acid sequences of the aplpha and beta chains of adult hemoglobin of the tupai, tupaia glis.globin prepared from hemoglobin of adult tupai (tupaia glis) was separated into alpha and beta polypeptide chains by cm-cellulose column chromatography. the s-aminoethylated alpha polypeptide chain and s-carboxymethylated beta polypeptide chain were each digested with trypsin, and the sequences of all the peptides thus obtained were established. the ordering of these tryptic peptides in the alpha and beta polypeptide chains was deduced from the homology of their primary structures with that of h ...1977410801
body weight: its relation to tissue composition, segment distribution, and motor function. i. interspecific comparisons.the composition of skin, muscle, and bone and their distribution throughout the body are compared for "advanced" or "specialized" species (alouatta, macaca, canis, felis, lepus); smaller, more closely related species (tupaia and the lorisidae); and several species within the same ecosystem (barro colorado island, panama). among the most significant variables, the skin of sloths, howlers and macaques constitutes more than 12% of body weight, whereas greyhound skin is 5% of weight; sloth and howle ...1977410305
establishment of a variant cell clone growing at 41 degrees c from embryonic rat and tupaia (tree shrew) fibroblast cells.rat and tupaia 41 degrees c temperature variant cell clones were derived from parental embryonic cells, cloned and established in tissue cultures. both variant cell clones grew permanently at 41 degrees c. the morphology of these cell clones was altered in comparison to the original fibroblast cell clones. the cell biological characterization of the rat and tupaia 41 degrees c temperature variant cell clones showed that both cell clones were stable. after abolishing the selection pressure (incub ...1978567184
induction of liver tumors by aflatoxin b1 in the tree shrew (tupaia glis), a nonhuman primate.the epidemiological studies suggest that aflatoxins, the toxic metabolites of the ubiquitous mold aspergillus flavus, may play a significant role in the evolution of hepatocellular carcinoma in man in certain geographic areas of the world. to ascertain their carcinogenicity in nonhuman primates, we have administered highly purified aflatoxin b1, intermittently in the diet at 2 ppm, to 10 female and 8 male tree shrews. the tree shrew (tupaia glis) is a nonhuman primate occurring throughout southe ...1976174805
behavior alterations in tree shrews (tupaia glis, diard 1820) induced by borna disease virus.intracerebral injection of borna disease virus in tree shrews led to a persistent infection that sometimes resulted in clinical symptoms and/or specific alterations in the animals' behavior. whereas infective virus in the brain and in the serum antibodies were always present after infection, only some of the animals showed signs of clinical disease and behavior changes. animals kept in pairs showed especially obvious behavior alterations expressed as an exaggeration of all the components of norm ...1978566371
tupaias (tree shrews)--a new animal model for gallstone research. ii. influence of fat, sugar, and cholesterol on bile composition.the lipid composition of bile obtained from the gallbladder and from the liver of tupaias was determined. compared to the gallbladder bile of man, the gallbladder bile of tupaias contains the same percentage of phospholipids (pl), one third of the cholesterol (ch), and 50% more total bile acids (tba). the lithogenic index (li) of the bile is about 0.2--0.3. no significant sex differences or diurnal variations are found in the composition of bile. the concentration of pl, ch, and tba is found 5 t ...1979121164
are there specialized junctions in the pars maculata of the distal tubule?in the present study the tight junctions at the macula densa were compared to those of the adjacent straight and convoluted segments of the distal tubule using freeze fracturing and thin sectioning techniques. only insignificant differences were found in the number of strands and the apico-basal depth of the tight junctions in the three distal tubular segments of rat, dog and tree shrew. in experiments with horseradish peroxidase on mice and tree shrews, the tracer did not penetrate the apical j ...1979487402
hepatic drug metabolism in bushbabies (galago crassicaudatus and galago senegalensis) and tree shrews (tupaia glis). 1979113012
interlaminar connections of tree shrew visual cortex.the intracortical projections of neurons in layers ii and upper iii of tree shrew visual cortex were studied after terminal lesions in the supragranular layers of area 17. examination for terminal degeneration was made using ultrastructural techniques. the majority of degenerating terminals were found in layers v and, to a lesser extent, vi, and were presynaptic to neural profiles in the following distribution: 80.5% on spines of small to medium size dendrites, 19% on dendrite shafts, and less t ...1979111169
some affinities and differences between the submandibular glands of the primates, tree-shrew (tupaia glis), insectivora and some other kinds of animals. 1978104216
experimental infection of tupaia belangeri (tree shrews) with herpes simplex virus types 1 and 2.the susceptibility of tupaia belangeri (tree shrews, which are primitive prosimian primates) to infection with herpes simplex virus (hsv) and the pathogenesis of hsv in these animals were investigated. juvenile (28--45 days old) and adult (150 days old) animals were inoculated intravenously, intraperitoneally, or subcutaneously with hsv type 1 or 2 (25--10(5) plaque-forming units per animal). clinical illness usually appeared in juvenile animals on the second day after inoculation, and the anima ...1978204709
the influence of dose on the pattern of conjugation of phenol and 1-naphthol in non-human primates.1. the pattern of conjugation of phenol and 1-naphthol was investigated in several primates; three old world species (rhesus, cynomolgus, patas monkeys), two new world species (capuchin, tamarin), and two prosimians (bushbaby, tree shrew). 2. following intra-muscular phenol or 1-naphthol (10 mg/kg), sulphation was the major conjugation in the old world monkeys and prosimians, whereas glucuronidation predominated in the new world species. 3. in rhesus and cynomolgus monkeys, sulphation decreased ...197898922
horseradish peroxidase-labelled cells in cervical sympathetic and trigeminal nervous systems after injection of hrp into tooth pulp in monkeys and tree shrews (a preliminary report).the neurons that project to the tooth pulp were examined by the hrp-retrograde transport technique, using 4 monkeys (3 japanese monkeys and a crab-eating monkey) and 6 tree shrews. the present investigation showed that a large number of sympathetic cervical ganglion neurons, small and medium in size, project to the molar teeth from the superior, middle and inferior ganglia and a small number of gasserian gangilon neurons (small in size) to the molar teeth ipsilaterally.197987281
the actions of 5-hydroxytryptamine and histamine on the isolated ileum of the tree shrew (tupaia glis).1. contractions to 5-hydroxytryptamine (5-ht) and histamine of longitudinal muscle from the isolated ileum of the tree shrew (tupaia), guinea-pig and rat were investigated by constructing dose-response curves and studying the effects of various antagonists. 2 in the tupaia and rat ileum the contraction to 5-ht was reduced by methysergide but not affected by tetrodotoxin (ttx), morphine, hexamethonium (c6) or atropine. the response of guinea-pig ileum to 5-ht was not significantly inhibited by me ...197943173
the induction of acute and chronic cardiovascular disease in animals by psychosocial stimulation.it has been established that sustained emotional arousal can accompany the psychosocial stimulation induced by the social interaction of members of a social group as they compete for desiderata, such as food and water. this paper reviews the evidence that this arousal of neuronendocrine response patterns can, in turn, lead to disease states and to a fatal outcome. various experimental observations in pigs, monkeys, baboons, tree shrews, and rodents demonstrate both acute and chronic disturbances ...1975131784
amino acid sequences of the alpha and beta chains of adult hemoglobin of the european hedgehog, erinaceus europaeus.globin prepared from hemoglobin of the european hedgehog (erinaceus europaeus) was separated into alpha and beta polypeptide chains by chromatography on a cm 52 column. the s-aminoethylated alpha and beta chains were each digested with trypsin and the resulting peptides were isolated. the sequences of all the tryptic peptides were established. the ordering of these peptides in the alpha and beta chains was deduced from their homology with the primary structures of alpha and beta chains of human ...1979762046
partial characterization of hepatic micorsomes from tupaia glis.the dithionite difference spectrum of tupaia microsomal cytochrome p-450-co complex has an absorbance maximum at 449 nm, rather than at 450 nm as found for rat, rabbit, mouse, guinea pig, and human microsomes. n-octylamine difference spectroscopy showed the ratio of high- and low-spin forms of cytochrome p-450 to be different from that of the rat, indicating that the 449 nm absorption maximum might be due to a high concentration of the high-spin form, cytochrome p-448. the tupaia microsomes demo ...1975804714
dorsal root afferents to clarke's column from hindlimb cord levels in tupaia and galago.the projection of hindlimb dorsal root afferents to clarke's column has been studied in the tree shrew (tupaia glis) and lesser bushbaby (galago senegalensis). in the bushbaby, fibers from k12, l1 and l3 projected ipsilaterally to clark's nucleus from levels l3 to t3, l2 to t4 and l3 to t5 respectively. in tupaia, afferents from t11, l1, and l3 terminated ipsilaterally within the nucleus from segments l2 to t4, l3 to t6, and l3 to t8. fibers from t12, l1, and l3 in galago and t11 in tupaia termi ...1975805631
anatomical distribution of estrogen in the central nervous system of mouse, rat, tree shrew, and squirrel monkey. 1975809304
some affinities and differences between the tree-shrews (tupaia), insectivora and primates. 1975809737
tupaias (tree shrews)--a new animal model for gallstone research; first observations of gallstones.in tupaias, rat-sized mammals with phylogenetic affinities to insectivores and primates, gallstones can be induced by diet. twenty per cent butter, 20% sucrose, and 1% cholesterol, added to the standard diet, caused massive stone formation in 11 of 16 male tupaias. in the other five animals the bile contained cholesterol crystals or few stones, liquid crystals, and fat droplets. the stones were composed almost totally of cholesterol and closely resembled those described in squirrel monkeys, whic ...1979118503
the ascent of man: deductions based on a multivariate analysis of the brain.this paper attempts to investigate taxonomic and phylogenetic relationships through an analysis of the distribution of mass within the brain. a multivariate analysis was performed on encephalization ratios for various divisions of the brain, employing volume measurements reported for 63 species by stephan et al. [1970]. the ratios for each brain region were considered to lie along one of the dimensions of eight dimensional 'brain space', and distances between all species were calculated and empl ...1975810216
behavioral study of the visual cortex of galago senegalensis.an ablation study of the visual cortex of galago senegalensis was undertaken in the hope of finding clues about the evolution of primate visual cortex. removal of area 17 resulted in a profound sensory loss manifested by, first, the failure to discriminate between simple patterns; second, a deficit in localizing objects; third, a deficiency in tracking moving objects; and fourth, symptoms attributable to a deficiency in depth perception, such as misreaching and inaccurate jumping. thus, the effe ...1975811692
digenetic trematodes from rats, squirrels and tree shrews in malaysia.neodiplostomum (conodiplostomum) brachylaima, ectosiphonus and euparadistomum are reported for the first time from small mammals in malaysia. new host and locality records are given for echinostoma, achillurbainia, beaveria, odeningotrema, leipertrema, athesmia, skrjabinus and zonorchis. possible-life-cycles of the parasites are discussed in relation to the ecology and feeding habits of the hosts.1975816008
the chromosomal location of rdna in selected lower primates.hybridization in stiu was used to identify the chromosomes that carry rdna in representative lower primates, including the baboons, papio cynocephalus and papio hamadryas; the colobus monkey, colobus polykomos; the tree shrew, tupaia glis; the lemur, lemur fulvis; the saki, pithecia pithecia; the marmoset, saguinus nigricollis, and the spider monkey, ateles geoffroyi. the marker chromosome, common to the cercopithecines studied to date, carries the rdna in the baboons. another marker chromosome ...1977414888
[nematodes of the genus spirura, parasites of tupaia and nycticebus in malaysia (author's transl)].morphological study of two spirura parasites of the oesophageal and the gastric wall of tupaia and nycticebus in malaysia. -- spirura malayensis n. sp. is found both in tupaia in the district of selangor (west malaysia) and in nycticebus coucang in borneo. its very primitive characteristics relate it to s. diplocyphos chabaud, brygoo and petter, 1965, parasite of lemurs from madagascar. its larval development was obtained experimentally in blatella germanica. -- spirura aurangabadensis (ali and ...1975818936
a comparative survey of the mast cells of the mammalian brain.a search for mast cells has been made in the brains of 18 mammalian species in 13 families in the orders insectivora, primates, rodentia and carnivora. in the larger animals, only the diencephalon and olfactory bulbs were examined. mast cells were identified by virtue of their heparin-containing granules, which are stained by alcian blue 8gx and, metachromatically, by toluidine blue 0. within the cerebral parenchyma, mast cells were confined to the dorsal diencephalon of erinaceus europaeus (hed ...1976819404
crystalloid configuration in the adrenal cortex of the siamese tree shrew (tupaia glis).crystalloids of what appear to be smooth reticulum have been observed in the zona fasciculata and zona reticularis in both the stressed and nonstressed adrenal gland of the siamese tree shrew (tupaia glis). no crystalloids are observed in the zona glomerulosa. similar crystalloids have been described in other steroid-secreting organs, including the antebrachial organ of the lemur (lemur catta), the parotoid gland of bufo alvarius and in sebaceous gland cells of the galagos and macaques. moreover ...1976820215
the intercollicular area of the inferior colliculus.to study the somatosensory input to the inferior colliculus, lesions were made in the dorsal column nuclei of the hedgehog, tree shrew, slow loris, marmoset and african green monkey, and spinal cord of the hedgehog, tree shrew and slow loris. the degenerating fibers stained with silver impregnation methods. the dorsal column system projects primarily to an area lateral to the central nucleus of the inferior colliculus, whereas the spinotectal projection is primarily to the medial region in the h ...1976825188
prolonged hematopoiesis in a primate bone marrow culture system: characteristics of stem cell production and the hematopoietic microenvironment.maintenance of myelopoiesis and pluripotential stem cell production for prolonged periods in vitro hitherto has been limited to mouse bone marrow culture. in an effort to adapt the system for use in higher species, particularly in human and non-human primates, studies were undertaken using the prosimian species, tupaia glis (tree shrew). in a number of experiments the duration of sustained normal hematopoiesis observed in cultures of this species, following a single inoculum of 5 x 10(6)--10(7) ...1979476301
auditory pathways to the cortex in tupaia glis.the auditory system of the tree shrew, tupaia glis, was investigated by identifying axonal degeneration after lesions of the lateral lemniscus, the inferior colliculus, the medial geniculate nucleus and the auditory cortex. the results show that the lateral lemniscus projects to the central nucleus of the inferior colliculus which in turn projects principally to the ventral division of the medial geniculate nucleus but to a lesser extent to the magnocellular division of the medial geniculate nuc ...1976816825
a comprehensive study of in vitro drug metabolism in several laboratory species.a shortage of rhesus monkeys for use in drug toxicity studies has made it necessary to search for a potential replacement species in the event that one should be needed in the near future. to this end, 14 parameters of drug metabolism in hepatic microsomal and soluble fractions were examined in preparations from adult male and female rhesus monkeys, squirrel monkeys, hanford miniature pigs, common tree shrews, and sprague-dawley rats. model substrates were utilized and comparisons were made on a ...19766223
masking, de lange curves and integration time as revealed by the electroretinogram of a tree shrew (tupaia chinensis).dynamical characteristics of the electroretinogram (erg) of a tree shrew were measured. since this animal has a cone dominated receptor population (95%) comparison to human photopic vision is obvious. the light source was chosen to stimulate the red cones of this deuteranopic animal predominantly. masking experiments displayed a reasonable correspondence to human foveal psychophysics. de lange curves and cff values revealed a maximum sensitivity at 15-20 hz, which is higher than is found for hum ...1978416417
the precise origin of the tectospinal pathway in three common laboratory animals: a study using the horseradish peroxidase method.the horseradish peroxidase tracing method has been used to study the cells of origin of the tectospinal projections in the opossum, the tree shrew, and the cat. the present data show that only those collicular neurons which occupy the deep (ventral to the stratum opticum) tectal laminae send axons to the cervical spinal cord. in particular, layer iv contains the greatest number of spinal projecting neurons. our results also reveal that while only the large sized collicular neurons project upon t ...1979460682
the medial geniculate body of the tree shrew, tupaia glis. ii. connections with the neocortex.in this study the temporal cortex of the tree shrew was subdivided on the basis of cytoarchitectonic criteria, and the connections of each subdivision with the thalamus and midbrain were analyzed with retrograde and anterograde techniques. the results indicate that, with one exception, each subdivision of the medial geniculate body projects to a separate cortical area. the primary auditory cortex receives projections from the ventral nucleus. surrounding the primary cortex are at least five addi ...1978102661
distribution of 125i-endothelin-1,-2,-3 binding sites in mammalian kidneys.1. binding sites for 125i-labeled endothelin (et) isopeptides et-1, et-2 and et-3 were visualized by autoradiography in the kidneys of man, baboon, rhesus monkey, tree shrew, pig and rat. 2. highest levels of binding for the three isoforms were observed in the glomeruli, cortical and medullary vessels of baboon, rhesus monkey, pig and rat, whereas there was no noticeable labeling of glomeruli in human and tree shrew kidneys. 3. the enrichment of binding sites depended on the species and peptide ...19921351453
the medial geniculate body of the tree shrew, tupaia glis. i. cytoarchitecture and midbrain connections.in this study of the medial geniculate body in the tree shrew eight subdivisions are identified on the basis of differences recognized in nissl-stained material. experiments using the methods of anterograde and retrograde axonal transport and anterograde degeneration show that each subdivision has a unique pattern of connections with the midbrain. the ventral division of the medial geniculate body contains at least two subdivisions, the ventral nucleus and the caudomarginal nucleus. the ventral ...1978102660
pancreatic microcirculation in the common tree shrew (tupaia glis) as revealed by scanning electron microscopy of vascular corrosion casts.pancreatic vascular casts of the common tree shrew (tupaia glis) were prepared by infusion of batson's no. 17 plastic mixture into the blood vessels and examined by scanning electron microscopy (sem). routine histological study of the pancreas was also performed. it was found that the a and d cells appeared to occupy the core whereas the b cells were found at the periphery of the islets of langerhans. with sem, the insular arteriole, a branch of the interlobular artery, was shown to penetrate de ...19921632182
anatomical and neurobehavioral investigations concerning the thalamo-cortical organization of the rat's visual system.the organization of thalamic afferents to the rat's visual cortex was investigated autoradiographically and through the retrograde transport of horseradish peroxidase (hrp) following infections into striate and peristriate cortex. the results revealed that nucleus lateralis posterior (nlp) projects to a large peristriate cortical field that includes areas 18a, 7, and the anterior portion of area 18, and to a circumscribed temporal area corresponding to krieg's ('46a,b) area 20. the dorsal latera ...1977903426
[biological cycle of tarsubulura perarmata (ratzel, 1868) (author's transl)].tarsubulura perarmata (ratzel, 1868) is described from a primate tarsius bancanus and from tupaidae: tupaia glis and t. minor in malaysia (kuala lumpur). its biological cycle is done by the experimental infestation of crickets belonging to the genera valanga and oxya. the infective larvae are obtained after three weeks of development of 28 degrees c in the intermediate host. they differ from third stage larvae obtained from subulurinae by the development of cuticular pharyngeal lobes. the early ...1977907289
elimination of ul56 gene by insertion of lacz cassette between nucleotide position 116030 to 121753 of the herpes simplex virus type 1 genome abrogates intraperitoneal pathogenicity in tree shrews and mice.in order to investigate whether or not the ul56 gene is involved in those processes determining the viral pathogenicity and latency, a recombinant virus hsv-1-m-lacz was constructed in which the dna sequences between nucleotide position (np) 116030 and 121753 were replaced by the e. coli beta-galactosidase (lacz) gene. this deletion spans from the carboxyterminus of ul55 (np 116030) to the second exon of ie110 (np 121753) eliminating ul56 and the variable region of the bamhi dna fragment b which ...19911662844
identification and mapping of the ul56 gene transcript of herpes simplex virus type 1.the herpes simplex virus type 1 (hsv-1) strain hfem is apathogenic for tree shrews and mice by the intraperitoneal application route. this is due to a 4.1 kbp deletion [0.762 to 0.789 map units (mu)] within the bamhi dna fragment b of the viral genome. with exception of 71 bp the dna sequences of the deleted region are located within the repetitive dna sequences of the inverted repeat of the l segment of the hsv-1 genome (irl). a 1.5 kb rna hybridizing to the dna sequences of the hsv-1 genome at ...19911651032
development of the lateral geniculate nucleus: interactions between retinal afferent, cytoarchitectonic, and glial cell process lamination in ferrets and tree shrews.we have studied the relationship of retinal afferents, glial cell processes, and neuronal cytoarchitectonics in the lateral geniculate nucleus (lgn) of two species: tree shrews (tupaia belangeri) and ferrets (mustela putoris). both species are relatively immature at birth, allowing the development of these features to be studied in the perinatal period. retinal afferents, visualized by intraocular injection of a wheat germ agglutinin/horseradish peroxidase conjugate (wga-hrp), are apparently the ...19901698826
molecular phylogeny of the superorder archonta.the superorder archonta has been hypothesized to include primates, tree shrews, bats, and flying lemurs as descendants of a common ancestor. more recently, a diphyletic origin for bats has been proposed. to evaluate these hypotheses, the nucleotide sequence of the mitochondrial cytochrome oxidase subunit ii gene was determined from a bushbaby (galago senegalensis), flying lemur (cynocephalus variegatus), tree shrew (tupaia glis), spear-nosed bat (phyllostomus hastatus), rousette bat (rousettus l ...19911658802
morphological details of primate axons and dendrites revealed by extracellular injection of biocytin: an economic and reliable alternative to pha-l.the objective of this study was to determine if biocytin would reliably label details of distant axons and dendrites when injected extracellularly in primates. biocytin (2.5-5%) was injected iontophoretically or by pressure into several areas of the visual and somatosensory systems of macaque monkeys, squirrel monkeys, tree shrews and galagos. after survival times that ranged from 9 h to 2 weeks, fine details of anterogradely filled axons and/or retrogradely filled dendrites were reliably reveal ...19911723335
parallel thalamic activation of the first and second somatosensory areas in prosimian primates and tree shrews.in tupaia belangeri and galago senegalensis, microelectrode recordings immediately after ablation of the representation of the forelimb in the midportion of the first somatosensory area, s-i, revealed that all parts of the second somatosensory area, s-ii, remained highly responsive to cutaneous stimuli. in this way, prosimian primates, close relatives of simian primates, and tree shrews differ markedly from monkeys in which s-ii is deactivated by comparable ablations, and resemble such mammals a ...19911753020
protein binding of cortisol by means of competitive adsorption: application to cortisol binding by serum of sixteen eutherian mammals.1. binding of 3h-cortisol by serum proteins by means of competitive adsorption was relatively high by serum of the gerbil, human, rabbit, sheep, tree shrew, hamster, rhesus monkey and horse. 2. a somewhat lower binding was observed by serum proteins of the baboon, cattle, dog, rat and cat. 3. serum taken from either the mouse, guinea pig or pig gave very flat binding curves, specific binding not exceeding 5% of added 3h-cortisol. 4. it is concluded that the measurement of protein-binding of 3h-c ...19911673379
hdl and apolipoprotein a1 (apo a1). their effects on retardation of lipid deposition in aortic intima.the aim of this study is to clarify whether apo a1 displays a similar role as that of hdl in preventing the development of experimental atherosclerosis. results were obtained from 4 groups of experiments. (1) result from 4 successive experiments of tree shrews indicated that high serum hdl level is the main factor in preventing the development of experimental atherosclerosis; (2) results from 4 successive experiments in rabbits showed that both hdl and apo a1 were able to decrease the extent of ...19921499365
[trbc receptor on t lymphocytes of human and macaque and its ligand are different from e2 molecule and ligands for cd2].cd2 (e receptor, lfa-3 receptor) and e2 molecules (bernard, 1988) on human t lymphocytes, cd58 (lfa-3, lymphocyte function associated antigen 3) on human erythrocytes and s14,s42,s110-220 molecules (bernard, 1987) of sheep erythrocytes are involved in rosette formation of human t lymphocytes with human or sheep erythrocytes. rosette formation of human and macaque pan-t lymphocytes with tree shrew (tupaia belangeri) red blood cells (trbc) (trbc rosette) has shown different physicochemical propert ...19901708938
tupaiataenia quentini gen. et sp. n. (anoplocephalidae: linstowiinae) and other tapeworms from the common tree shrew, tupaia glis.three species of cestodes recovered from tree shrews, tupaia glis, were identified as sparganum sp., hymenolepis diminuta, and tupaiataenia quentini gen. et sp. n. the new genus is differentiated from mathevotaenia, markewitchitaenia and atriotaenia by being craspedote, possessing a large seminal receptacle, the presence of a hermaphroditic canal leading into the genital atrium, and by having two opposable, muscular lappets on the anterior margin of each sucker.1977864565
pneumocystis carinii infections in zoo animals.pneumocystis carinii was found to be present in the lungs of twenty-three zoo animals in the netherlands. the following species were represented: red kangaroo, common tree shrew, senegal-galago, demidoff's-galago, brown howler monkey, woolly monkey, long-haired spider monkey, white-eared marmoset, chimpanzee, three-toed sloth, palm squirrel, red panda, fennec fox, tree hyrax and large-toothed hyrax.19751079994
origins of anthropoid intelligence.the development of the extrastriate visual system relative to the striate system was estimated indirectly by measuring the volumes of the lateral posteriorpulvinar complex and lateral geniculate nucleus in six varieties of mammals selected on the basis of their propinquity with anthropoidea [oppossums, hedgehogs, rats, squirrels, tree shrews and bushbabies]. the same animals were tested on two related behavioral tasks [spatial and visual reversal learning] whose successful achievement requires a ...19751137814
photosensitive and photostable pigments in the retinae of old world monkeys.microspectrophotometric measurements of retinal receptors are reported for eight species of old world monkey. although the animals vary greatly in size, colourings and habitat, they all appear to be trichromats and the peak sensitivities of their cones invariably lie near 430, 535 and 565 nm. this consistent pattern contrasts with the results reported earlier for new world monkeys and with the results reported here for tupaia glis. the trichromacy of frugivorous catarrhine monkeys may have co-ev ...19912051127
[the visual cortex of tupaia: an alternative model?].the tree shrew has become an interesting animal for research in neurobiology because of its unique structural and functional properties, in particular in its visual system. some of these properties are described and discussed here as far as they are related to the functional architecture of the primary visual cortex: the representation of the ocularity, the on and off responses, the development of the retino-geniculo-cortical projection, and synaptogenesis. from these data it appears that the tr ...19911812170
[new nematodes of the genus trichospirura smith and chitwood, 1967, in malaysia. remarks on the evolution of the family rhabdochonidae (author's transl)].description of trichospirura willmottae n. sp. parasite of the salivary ducts of tupaia glis and t. sp. (single virgin female) parasite of the intestine of myotis mystacinus in malaysia. the two species are very closely related to the type species, a parasite of the pancreatic ducts of brasilian primates, and can be differentiated mainly by the mensurations of the posterior extremities of the bodies. while the genus rhabdochoma, parasite of the intestine of fresh-water fishes, underwent a very s ...19751227382
postnatal development of area 17 callosal connections in tupaia.the goal of the present study was to investigate the pattern of maturation of callosal projecting neurons in a well-studied mammalian visual system with unique structural and functional properties. studies of the distribution pattern of interhemispheric connections in the adult tree shrew primary visual cortex reveal not only a high concentration of labeled neurons along the area 17/18 border, as in standard experimental animals such as the cat and monkey, but also numerous callosal projecting n ...19921282524
current status of food-borne parasitic zoonoses in singapore.parasitic infections adopt a rather low profile in the highly urbanized setting in singapore. very few food-borne parasitic infections are encountered. apart from a few reports of infections with clonorchis/opisthorchis, taenia spp. and hydatid disease, there are no other citations of such helminthic infections. seroprevalence surveys have shown the presence of toxoplasmosis in local meat animals (sheep, pigs and cattle) and toxoplasma strains have been isolated from the pig, tree shrew (tupaia ...19911822903
[comparative study of trbc receptor and e receptor on t lymphocytes of human and macaque].in 1985, rosette formation of human and macaque pan-t lymphocytes with tree shrew red blood cells (trbc) (trbc rosette) was first found by ben k et al, showing different physico-chemical properties from that of rosette formation with sheep red blood cells (e-rosette). in order to approach the correlation between trbc receptor, e receptor (cd2) and other differentiation antigens (cds) on t lymphocytes, rosette inhibition assay and antigenic modulation or co-modulation were performed with monoclon ...19901974378
alpha 2-adrenergic binding sites in the medulla oblongata of tree shrews demonstrated by in vitro autoradiography: species related differences in comparison to the rat.alpha 2-adrenergic binding sites in the medulla oblongata of tree shrews and rats were detected and quantified by in vitro-autoradiography with the alpha 2-antagonist 3h-rauwolscine (3h-rauw). the autoradiographic pattern of the radioligand binding in the tree shrew medulla oblongata resembles that which has been described by others for the human myelencephalon. this pattern coincides well with the occurrence of catecholaminergic structures detected by immunocytochemistry with antibodies against ...19901973422
the retinohypothalamic projection and oxidative metabolism in the suprachiasmatic nucleus of primates and tree shrews.this study compared the patterns of retinal projections and oxidative metabolism in the hypothalamus of squirrel monkeys, bonnet macaques, and tree shrews. intraocular injections of horseradish peroxidase in primates demonstrated that retinal terminals were present from the anterior to posterior poles of the suprachiasmatic nucleus (scn). the terminals were primarily located in the ventral and ventrolateral regions of the scn. in addition, there was a relatively even density and distribution of ...19902169949
preliminary observations on experimental leprosy in tupaias (tupaia belangeri yunalis).the tupaia belangeri yunalis (tree shrew) is one of the primitive primates. they were inoculated subcutaneously in the footpad or intravenously with mycobacterium leprae from a patient with multibacillary leprosy. as controls, the footpads of cfw mice were inoculated with the same suspension of m. leprae. the results showed growth of acid-fast bacilli (afb) in the footpads of locally inoculated cfw mice and in the footpads of both locally and intravenously inoculated tupaias. whereas the numbers ...19902181220
rod bipolar cells in the cone-dominated retina of the tree shrew tupaia belangeri.the tree shrew has a cone-dominated retina with a rod proportion of 5%, in contrast to the common mammalian pattern of rod-dominated retinae. as a first step to elucidate the rod pathway in the tree shrew retina, we have demonstrated the presence of rod bipolar cells and studied their morphology and distribution by light and electron microscopy. rod bipolar cells were labeled with an antiserum against the protein kinase c (pkc), a phosphorylating enzyme. intense pkc immunoreactivity was found in ...19911883767
light and electron microscopy of the structural organization of the tissue-lymphatic fluid drainage system in the mesentery: an experimental study.supplementing vital microscopy and histophysiology, we examined using combined light and electron microscopy the tissue fluid-lymphatic drainage system of the mesentery isolated from guinea pigs, rabbits, and tree shrews. in silver impregnated tissue, different types of lymphatics and blood vessels were able to be distinguished along with argyrophilic and argyrophobic structures in the connective tissue. some initial lymphatic pathways were interrupted by non-endothelialized tissue zones thus fo ...19911921481
high density lipoproteins and prevention of experimental atherosclerosis with special reference to tree shrews.according to data obtained from epidemiological and experimental survey, serum hdl level is known to be correlated conversely with the incidence of atherosclerosis. experimental data collected in this article explained part of its mechanism, which is described in four parts as follows: 1. the result of 3 successive experiments on experimental atherosclerosis in tree shrews (total of 96 animals available including 40 as the controls) showed that the serum hdl level had been kept persistantly to 6 ...19902123379
a blood capillaries-bridging cell type in adult mammalian brains.for the investigations we used coronal-sectioned series of adult brains from wistar-rat, white mouse, cat, tree-shrew (tupaia glis), and rhesus monkey (macaca mulatta) in which the blood capillaries bridging cells (bcs) had been demonstrated by different silver-impregnation procedures (golgi-kopsch, gallyas, bär and budi santoso) and by complex staining with lfb + pas + hematoxylin, too. the bcs could be found in many cortical and subcortical brain areas of the 5 mammalian species under study. a ...19882460522
magnocellular nuclei of the basal forebrain project to neocortex, brain stem, and olfactory bulb. review of some functional correlates.horseradish peroxidase was injected into the neocortex of squirrel monkeys, rats, tree shrews and one opossum, in the brain stem of one squirrel monkey and rats, and in the olfactory bulb, the corpus vitreum or the vascular system of rats. following the cortical, brain stem and bulbar injections labeled cells were found (predominatly ipsilaterally) in the magnocellular nuclei of the basal forebrain: nucleus of the diagonal band, the magnocellular preoptic nucleus and nucleus basalis. these nucle ...19751174977
organotropism of latent herpes simplex virus type 1 is correlated to the presence of a 1.5 kb rna transcript mapped within the bamhi dna fragment b (0.738 to 0.809 map units).the transcriptional activity of the dna sequences within the genome of herpes simplex virus type 1 (hsv-1) at the coordinates 0.760 to 0.762 and their influence in the process of viral latency were investigated. seven avirulent hsv-1 strains (hfem, 1752/2, 1752/3, 1752/11, 1469, 1475, 1618), two virulent wild-type hsv-1 strains (f and 17) and three virulent intratypic hsv-1 recombinant viruses (r19, r26, rm1c1) were screened. the virulent hsv-1 strains colonize the ganglia but the avirulent viru ...19892541581
activation of glycogenolysis by stimulation of the hepatic nerves in perfused livers of guinea pig and tree shrew as compared to rat: differences in the mode of action.a study on the metabolic and hemodynamic actions of hepatic nerve stimulation in the perfused liver of guinea pig and tree shrew as compared to rat was performed, since the density of liver innervation was reported to be different. 1) nerve stimulation resulted in an increase in glucose release and decrease in lactate uptake or in a shift to output as well as a decrease in portal flow in all three species. the change in glucose output was very similar, that in lactate balance and flow was smalle ...19902334519
[comparative anatomic studies of the tongue of pan troglodytes (blumenbach, 1799) and other primates. i. the chimpanzee tongue].this study was carried out on a comprehensive collection of tongues of pan troglodytes. material of tongues of tupaia glis, microcebus murinus, chirogaleus major, lemur catta, galago crassicaudatus, cebus apella, and macaca mulatta were used for comparison of the different stages of the development of the papilla foliata. the tongue of pan exhibits longitudinal growth correlated with the growth of length of the jaws and individual age. a typical foramen caecum as it occurs in man was gross anato ...19902242823
[a study on primary liver cancer in tree shrews induced by human hepatitis b virus and aflatoxin b1].among 41 tree shrews exposed to aflatoxin b1(afb1), 17 were experimental infected by human hepatitis b virus (hhbv) and 24 were uninfected. after 158 weeks, 9 cases (52.94%) of primary liver cancer (plc) were found out of the 17 tree shrews infected by hhbv and only 3 cases (12.5%) developed plc in the 24 uninfected animals. significant difference of plc incidence was seen between the hhbv-infected and uninfected groups (p less than 0.05). moreover, 1/9 of the tree shrews that had been infected ...19892505943
macaque accessory optic system: i. definition of the medial terminal nucleus.the organization of the accessory optic system (aos) has been studied in the macaque monkey following intravitreal injections of tritiated amino acids in one eye. retinal projections to the dorsal (dtn) and the lateral (ltn) terminal nuclei are identical to those previously described in other primate species. we observed an additional group of retinorecipient cells of the aos, located between the cerebral peduncle and the substantia nigra, which we define as the interstitial nucleus of the super ...19902289977
comparative effects of ouabain on isolated papillary muscle from tree shrews, guinea-pigs and rats.inotropic effects of ouabain were investigated in the isolated papillary muscle preparations of the tree shrew (tupaia glis), guinea-pigs and rats. in the guinea-pig and shrew papillary muscles, ouabain at concentrations of 10(-8) to 3 x 10(-7) m caused a concentration-dependent positive inotropic response in a similar magnitude, while in the rat, ouabain at concentrations of 10(-7) to 3 x 10(-6) m elicited negative inotropic one. either phentolamine or pindolol in a concentration sufficient to ...19892568455
[fatty acid compositions of cholesteryl esters. different species and their correlation with susceptibility to atherosclerosis].fatty acid compositions of serum cholesteryl esters (ce) in human and animals were analysed. polyunsaturated fatty acids (pufa) were the predominant fatty acids in ce. a close relation between pufa to saturated fatty acids (p/s) ratio in ce and susceptibility to atherosclerosis (as) was observed among different species. animals with high p/s such as tree shrews and rats (p/s 9.0) were as-resistant, and those with low p/s such as rabbits (p/s 2.9) were susceptible to as. the p/s ratio in human se ...19921337719
dark-rearing interference with emmetropization in the rhesus monkey.dark rearing has been shown to protect against the development of lid-suture myopia in monkeys and tree shrews. dark-reared monkeys and cats, with or without lid suture, are significantly hyperopic in comparison to light-reared controls. the time course of refractive change during dark rearing has only been systematically investigated in chicks, with hyperopia increasing from 14 to 42 days after hatching. longitudinal refractions of dark-reared monkeys have not been reported previously. five inf ...19892703319
histamine-immunoreactive nerve fibers in the mammalian spinal cord.new sensitive antisera against histamine were used to study the distribution of histamine-immunoreactive nerve fibers in the spinal cord of several mammalian species. tissues were fixed with carbodiimide by transcardiac perfusion or immersion. a few immunoreactive nerve fibers were found in the cervical spinal cord of the rat in the superficial laminae of the dorsal horn, around the central canal and scattered in the anterior horn. the density of immunoreactive fibers in the cervical spinal cord ...19892713684
stereo architecture of the connective tissue cores of the lingual papillae in the treeshrew (tupaia glis).the stereo architecture of the lingual connective tissue cores (ctc) in the treeshrew (tupaia glis) (which has the primitive characteristics of primates) was observed by scanning electron microscopy, and compared to that of other animal orders. the tongue of the treeshrew has three vallate papillae which are situated in the posterior part of the tongue, while some macaques have several vallate papillae. among numerous filiform papillae, fungiform papillae are sporadically distributed. a filiform ...19921292368
demonstration in tupaia papillary muscle preparations of alpha-adrenoceptors mediating positive inotropic effects: comparison with guinea-pigs.1. positive inotropic responses to alpha- and beta-adrenoceptor agonists of isolated papillary muscles from the tree shrew (tupaia), were compared with those from guinea-pigs. 2. in tupaia, the concentration-response curve for phenylephrine, unlike that for isoprenaline, was not affected by pindolol in a concentration (10(-8) m) sufficient to block beta-adrenoceptor-mediated responses, but it was significantly shifted to the right by phentolamine (10(-6) m). in guinea-pig papillary muscles, howe ...19892573402
effects of bicuculline on signal detectability in lateral geniculate nucleus relay cells.the lateral geniculate nucleus conveys the center-surround organized retinal receptive fields to the cortex in a way that does not significantly alter their spatial structure. however, non-retinal influences may change the 'strength' (detectability) of the signal under conditions of anesthesia, arousal and attention. a previous analysis of receiver operating characteristic curves in cat suggests that a reduction in signal detectability occurs in lateral geniculate nucleus (lgn) relay cells in an ...19892743129
comparative analysis of the transcripts mapped in the bamhi dna fragment b of avirulent hsv-1 hfem, virulent hsv-1 f, and their intratypic recombinant viruses.hsv-1 hfem, whose genome harbors a deletion of 4.1 kbp (0.762 to 0.789 map units (mu] is avirulent for mice and tree shrews by the intraperitoneal (i.p.) application route. insertion of the bamhi dna fragment b (0.738 to 0.809 mu) and/or the mlui dna fragment (0.7615 to 0.796 mu) molecularly cloned from virulent hsv-1 f, restored the i.p. pathogenicity to strain hfem and led to the isolation of virulent intratypic recombinants. in order to determine the rna transcripts mapped in the bamhi dna fr ...19882842976
atrial natriuretic peptide detected by immunocytochemistry in peripheral organs of tupaia belangeri.anp (atrial natriuretic peptide), a peptide found in granules of mammalian atrial cardiac myocytes, has been shown to be active in regulation of blood pressure and body water homeostasis. the existence of anp in atrium, pituitary, adrenal gland, and kidney of the rat had been immunocytochemically demonstrated with an antibody against rat anp (102-126). we used the same antibody in immunocytochemical studies for the detection of anp in peripheral organs of the tree shrew (tupaia belangeri). the a ...19872953699
natural herpesvirus hominis infection of tree shrews (tupaia glis). 19724340293
[experimental infection of human hepatitis b virus (hbv) in adult tree shrews]. 19872962750
characterization of prostaglandin e2 binding to uterine membranes from baboon, rabbit and tree shrew (tupaia belangeri).membrane preparations (100,000 g pellet) of rabbit, baboon and tree shrew (tupaia belangeri) uteri were studied for binding of [3h]prostaglandin e2 ([3h]pge2). unbound [3h]pge2 was separated by filtration through whatman gf/f filters. non-specific binding was determined by the amount of radioactivity associated with the filters in the presence of a 100-fold excess of radioinert pge2. pge2 bound to membranes could be displaced by some other prostaglandin (pg) molecules: pge1, 16,16-dimethyl-pge2, ...19892742743
replacement of the deletion in the genome (0.762-0.789 mu) of avirulent hsv-1 hfem using cloned mlui dna fragment (0.7615-0.796 mu) of virulent hsv-1 f leads to generation of virulent intratypic recombinant.the hfem strain of hsv-1 is apathogenic for the tree shrew by the intraperitoneal (i.p.) route because of a deletion in the genome coordinates 0.762-0.789. insertion of the mlui dna fragment (coordinates 0.7615-0.789) cloned from hsv-1 strain f, which is pathogenic for the tree shrew, restored the i.p. pathogenicity to strain hfem. the recombinant designated r-m1-c1 was highly pathogenic for the tree shrew, but slightly virulent for inbred mouse strain a. it thus appears that the viral dna seque ...19863020829
mammalian frontal diploic vein and the human foramen caecum.the course of the frontal diploic vein in the mole talpa and the tree shrew tupaia is described and compared to the frontal diploic vein of other mammals. the frontal diploic vein in talpa and tupaia connects the dorsal sagittal sinus to the veins of the orbit and has an emissary function. in certain other mammals it has a diploic function and may drain towards the orbit (e.g., orycteropus) or towards the dorsal sagittal sinus (e.g., didelphis). the frontal diploic vein of these mammals is not h ...19892712348
determination of the nucleotide sequence flanking the deletion (0.762 to 0.789 map units) in the genome of an intraperitoneally avirulent hsv-1 strain hfem.herpes simplex virus type 1 (hsv-1) strain hfem which harbours a deletion of 4.1 kbp in its genome (0.762 to 0.789 map units, hpai dna fragment p of hsv-1), is apathogenic for mice and tree shrews by the intraperitoneal application route. the exact position of this deletion was determined by dna sequence analysis. this analysis was performed using the recombinant plasmid pu18hshf-xmi-b which harbours the flanking genome regions (0.752 to 0.762 and 0.789 to 0.7895 map units) of the deletion in th ...19873035814
investigation of the virulence genes of herpes simplex virus 2 by experimental infection in vivo with defined intertypic recombinants of a virulent hsv-2 x an avirulent hsv-1.for determination of the gene loci for virulence and tropism of herpes simplex virus 2 (hsv-2) intertypic recombinants of hsv-1 strain hfem and hsv-2 strain 3345 were screened for their pathogenicity in the tree shrew. hsv-1 strain hfem is not pathogenic in the tree shrew and can be recovered as a latent virus only from the spleen of the animals; but hsv-2 strain 3345, the other parental virus of the recombinants, was found to be virulent for the tree shrew and colonized the ganglia of latently ...19853003551
scanning electron microscopic study on pineal vascularization of the common tree shrew (tupaia glis).the detailed blood supply including microvascularization of pineal gland in the common tree shrew (tupaia glis) was investigated using a vascular corrosion cast technique in conjunction with scanning electron microscopy. adult common tree shrews of both sexes, divided into 3 groups, were injected with red latex, blue vinyl resin, and batson's no. 17 plastic mixture for the studies of arterial supply, venous drainage, and microvasculature of the pineal gland, respectively. it was found that the p ...19912056434
the nucleotide sequence of the early region of the tupaia adenovirus dna corresponding to the oncogenic region e1b of human adenovirus 7.the nucleotide sequence of the early region e1b of the tree shrew (tupaia) adenovirus (tav) dna has been determined. the sequenced region includes the genes for polypeptides of mr 15 000, 44 000 and 13 400, which are analogous to the small and large e1b proteins and protein ix, respectively, of the three human adenovirus serotypes 5, 7, and 12. the hexanucleotide consensus signal aataaa occurs only at the 3' terminus of the gene for protein ix suggesting that the e1 region of tav encompasses one ...19853159623
application of a new, simple method for quantitative collection of 24-hour urines in small laboratory animals: determination of basal excretion of proteins, creatinine, urea, electrolytes, and of free steroids.the application of a simple method for collection of 24-hour urines in laboratory animals is described and basal excretion values of urinary proteins, creatinine, urea, electrolytes and of free steroids (glucocorticosteroids, dhea, progesterone, testosterone) in small laboratory animals like the mongolian gerbil, rat, guinea pig and tree shrew were measured. the major advantage of this method is that cages are identical in size to animal's home cages, are easily constructed and cheap, and that d ...19892756797
binding sites of atrial natriuretic peptide in tree shrew adrenal gland.adrenal gland binding sites for atrial natriuretic peptide-(99-126) (anp) were quantitated in tree shrew (tupaia belangeri) by incubation of adrenal sections with (3-[125i]-iodotyrosyl28) atrial natriuretic peptide-(99-126), followed by autoradiography with computerized microdensitometry. in the adrenal glands, there are three types of anp binding sites. one is located in the zona glomerulosa (bmax 84 +/- 6 fmol/mg protein; kd 122 +/- 9 pm); the second in the zona fasciculata and reticularis (bm ...19863025827
brain growth in man.25 male brains meeting the criteria for normativity and available in serial sections suitable for morphometric studies were selected from the yakovlev collection. growth parameters were calculated based on the generalized logistic function. the ideal weight is 1,313 g (sd = 41), with a half value time of 387 (sd = 26) ontogenetic days and a growth factor of 4.0 (sd = 0.5). comparison of growth parameters derived from a sample of 161 normative male brains collected at the department of neuroanato ...19863707509
[clearance effect of 3h-cholesterol by apo-ai/dppc liposome from cultured smc of rabbits and tree shrew].micellar liposomes were prepared by using apo-ai from rabbit or tree shrew and dipalmitoylphosphatidyl choline (dppc), with or without cholesterol through a rapid dialysis method. an obvious ability was noticed in clearing of 3h-cholesterol from the cultured smooth muscle cells (smc) and a cross effect of apo-ai originated from either rabbit's or tree shrew's serum on the clearance rate of 3h-cholesterol from the cultured smc of these two species of animals was also obtained.19902116940
laminar organization and ultrastructure of gaba-immunoreactive neurons and processes in the dorsal lateral geniculate nucleus of the tree shrew (tupaia belangeri).the distribution and ultrastructure of neurons and neuropil labeled by an antiserum to gamma-aminobutyric acid (gaba) were examined in the lateral geniculate nucleus (lgn) of the tree shrew (tupaia belangeri). the lgn of this species segregates center type and cell class into three distinct pairs of laminae: a medial pair (laminae 1 and 2) containing on-center cells, a more lateral pair (4, 5) containing off-center cells, and 2 laminae (3, 6) containing w-like cells. the relationship between thi ...19883154795
pretectal complex and accessory optic system of primates.in the present report, conflicting results regarding the pretectal complex and accessory optic system of primates are discussed. subsequently data are presented and used in an attempt to clarify some of the issues. the retinal projections to the pretectal complex and accessory optic system of the tree shrew and squirrel monkey were examined using anterograde autoradiographic methods. these data demonstrate that, following intraocular injections of 3h-proline or 3h-fucose in the tree shrew, silve ...19853907744
an allometric study of hippocampal components. a comparative study of the brains of the european hedgehog (erinaceus europaeus), the tree shrew (tupaia glis), and the marmoset monkey (callithrix jacchus).brains of western european hedgehogs, common tree shrews and common marmosets were perfused and stained according to timm's method. the volumes of hippocampal components were determined with semiautomated quantitative techniques and compared by allometric methods. the results support previous findings that the size of the hippocampus in marmosets and tree shrews is about twice that of the hippocampus of the european hedgehogs of the same body weight. three hippocampal substructures account for m ...19853939608
multiaxonal horizontal cells in the retina of the tree shrew, tupaia glis.the retinas of most vertebrates contain two or more morphologically distinct types of horizontal cell, and usually one of these types lacks an axon. among mammals, in which two types are observed, primates are exceptional in that both types of horizontal cell have axons. it then seemed of interest to study the horizontal cells of tree shrews (tupaia glis), insectivores thought to be closely related to primates. golgi impregnations of whole, flat-preparations revealed two types of horizontal cell ...19853980782
histaminergic system in the tree shrew brain.this study mapped the histamine-immunoreactive neuronal system in the brain of the tree shrew (tupaia belangeri) and compared its structure with that of the rat and guinea pig. the histamine-containing cell bodies lay in the posterior ventral hypothalamus in the tuberomammillary complex, as in the rodents. the morphology of this complex resembled that of the rat. the histaminergic axons projected to nearly all parts of the brain. the main ascending bundle ran ventromedially: the densest innervat ...19892768560
Displaying items 1 - 100 of 1295