| a histochemical study of the neuro-muscular spindles in the tongue of some rodents. | an investigation was undertaken to study the neuro-muscular spindles in the tongue (rattus rattus rufescens and suncus murinus) by cholinesterase technique, under maintained ph of 5.2, incubation period 20 h., and temperature 38 degrees c (rattus) and 39 degrees c (suncus). neuro-muscular spindles were observed frequently distributed from anterior to posterior of the tongue and took a little darker stain than the ordinary muscle fibres (negatively stained) while the nerve fibres and ganglia took ... | 1979 | 160147 |
| the occurence of coxiellosis among rodents and shrews in the tarai area of uttar praedesh. | rodents and shrews were screened for serologic evidence of coxiella burnetii. attempts were made to isolate the organism from the spleen and liver. seroreactors: total positive/total tested (% positive), in rats (rattus rattus, r. norvegicus), ground shrews (suncus murinus), bandicoots (bandicota indica, b. bengalensis) and the house mouse (mus musculus), respectively, were 13/105 (12.38), 6/42 (14.3), 2/15 (13.3) and 1/7 (14.3). of the eight rickettsial isolants recovered including four from fi ... | 1979 | 459035 |
| comparative neurohistological observations on the intrinsic innervation of pancreatic artery (blood vessel) in the representative of bird and mammal. | the present investigation was undertaken for the study of the comparative neurohistological observations of pancreatic-artery (blood vessel) in gallus domesticus (white leghorn) and suncus murinus (indian musk shrew) by cholinesterase technique. in gallus, the innervation of arteries (blood vessel) was by a good number of non-myelinated nerevs, which formed the periarterial plexus in participation with the postganglionic fibres at one end and the fibres of the nerve cells of the other end. in su ... | 1977 | 617554 |
| neurohistological observations on pancreas of suncus murinus (indian musk shrew). | | 1978 | 631658 |
| comparative breeding biology of musk shrews (suncus murinus) from guam and madagascar. | | 1977 | 908892 |
| capillaria hepatitis in the indonesian house shrew, suncus murinus. | | 1975 | 1226542 |
| grouping of hantaviruses by small (s) genome segment polymerase chain reaction and amplification of viral rna from wild-caught rats. | a single pair of consensus primers in the polymerase chain reaction (pcr) amplified a conserved region of the small genome segment of twenty hantavirus isolates. isolates tested included representatives of the four recognized hantaviruses, hantaan, seoul, puumala and prospect hill, as well as isolates from mus musculus (leakey), bandicota indica (thailand 749), and suncus murinus (thottapalayam). viruses from the nairovirus and phlebovirus genera yielded negative results. the amplification produ ... | 1992 | 1354416 |
| production of specific antibody against l-dopa and its ultrastructural localization of immunoreactivity in the house-shrew (suncus murinus) lateral habenular nucleus. | an antiserum was raised against l-dopa bound to bovine serum albumin, purified by affinity chromatography, and its specificities were verified by immunoblotting and enzyme-linked immunosorbent assays. the antiserum did not cross-react with dopamine (da), tyrosine, tyramine, octopamine, norepinephrine or epinephrine. immunocytochemical studies using the pap method revealed that tyrosine hydroxylase- and l-dopa positive but aromatic l-amino acid decarboxylase- and da-negative neurons were present ... | 1992 | 1359476 |
| morphological study of parafollicular cells and the parathyroid gland in the house shrew (suncus murinus). | a morphological study of parafollicular cells in the thyroid gland and parathyroid gland of the house shrew (suncus murinus) was made. the results indicated that (1) there were two pairs of parathyroid glands which were located in the upper part of the house shrew thyroid gland, (2) the volumes of the house shrew parathyroid glands ranged from 0.014 to 0.079 mm3, (3) the number of parafollicular cells along the follicles was largest in the upper part of the thyroid lobe, while no parafollicular ... | 1992 | 1436955 |
| intestinal disaccharidases in the house musk shrew, suncus murinus: occurrence of sucrase deficiency. | 1. disaccharidase activities of the small-intestinal brush border membrane were studied in six laboratory lines of the house musk shrew, suncus murinus. 2. sucrase activity was detected in all shrews of one line, but not in any shrew of three lines. in the other two lines it was found in some shrews, but not in the others. 3. maltase, isomaltase, trehalase and lactase activities were found in all shrews of all the lines examined. 4. sucrase was normally associated with isomaltase to form an enzy ... | 1992 | 1458837 |
| embryonic development of the house shrew (suncus murinus). i. embryos at stages 9 and 10 with 1 to 12 pairs of somites. | the embryonic development during the period from 1 to 12 pairs of somites was observed in an insectivore species, the house shrew (suncus murinus), which has been bred within a closed colony. embryos were staged by the number of somite pairs. each stage was punctuated at every addition of three pairs of somites and numbered after the carnegie system. the first somite became apparent between 8 and 9.0 days after fertilization, and the 12th somite appeared between 9.5 and 10.0 days. the rate of so ... | 1992 | 1514703 |
| dat-582, a novel serotonin3 receptor antagonist, is a potent and long-lasting antiemetic agent in the ferret and dog. | the antiemetic effects of a novel serotonin3 receptor antagonist, dat-582 [(6r)-(-)-n-[1-methyl-4-(3-methylbenzyl)hexahydro-1h-1,4- diazepin-6-yl]-1h-indazole-3-carboxamide dihydrochloride] were compared with those of the existing serotonin3 receptor antagonists, ondansetron and granisetron, in experimental animals. in ferrets, dat-582 (0.003-0.1 mg/kg i.v. twice) dose-relatedly prolonged the latency to the first emetic episode and decreased the number of emetic episodes induced by cisplatin (10 ... | 1992 | 1532032 |
| decrease in the content of cytochrome p450iie by fasting in liver microsomes of house musk shrew (suncus murinus). | the effects of fasting on hepatic cytochrome p450 in the mature male house musk shrew, suncus murinus (suncus), were studied by western blot analyses and enzyme assays. the content of p450iie protein was decreased, by fasting, to 24% of the control level in contrast to the results with rats, in which p450iie protein was increased to 172% by fasting. these changes reflected on catalytic activities, such as aniline hydroxylase and n-nitrosodimethylamine demethylase activities, which were decreased ... | 1992 | 1596279 |
| immunohistochemistry of the pituitary pars distalis of the musk shrew, suncus murinus. | immunocharacteristics of the pituitary pars distalis cell types of the musk shrew, suncus murinus, were studied by the unlabeled antibody enzyme technique, using peroxidase-antiperoxidase or avidin-biotin-peroxidase complex. the thyrotropin (tsh)-, gonadotropin (gth)-, corticotropin (acth)-, prolactin (prl)-, and growth hormone (gh)-secreting cells of the pd were identified on the basis of their immunoreactivity with different heterologous antisera. the tsh cells showed specific immunoreactivity ... | 1991 | 1663882 |
| response to opioids of isolated small intestine in the house musk shrew, suncus murinus. | 1. response to the opioids of isolated small intestine of suncus murinus, an insectivore, was examined and compared with that of guinea-pig ileum. 2. the mechanical response to morphine and u50,488h, preferential mu- and kappa-agonist respectively, was relaxation which was antagonized by tetrodotoxin and naloxone in the suncus small intestine. 3. methionine5-enkephalin and d-alanine2, d-leucine5-enkephalin, both preferential delta-agonists, elicited contraction or relaxation in the suncus small ... | 1991 | 1685436 |
| characterization of cell fusion in xc cells induced by suncus murinus mammary tumor virus. | syncytium formation in a rat tumor cell line (xc) induced by suncus murinus mammary tumor virus (sm-mtv) was studied. multinucleate giant cells containing 20-30 nuclei were formed in a monolayer of xc cells by cocultivation with x-ray-irradiated sm-mtv producing cells (sm-mt-1). by fluorescent antibody staining. sm-mtv antigens were demonstrated in the cytoplasm of syncytia, and budding particles and intracytoplasmic a particles were found in syncytial giant cells by electron microscopy. cell-fr ... | 1990 | 1701988 |
| deficiency of apolipoprotein b synthesis in suncus murinus. | we reported previously that fatty liver is easily induced in a novel experimental animal, suncus murinus (suncus) by withholding food. in this study, we focused on lipoprotein and apolipoprotein secretion from the liver. the study of lipoproteins from this animal revealed that small amounts of lipoproteins with apolipoprotein (apo) e but without apo b were observed in the fraction of density less than 1.08 g/ml. in order to learn whether apo b is synthesized by the liver or not, isolated suncus ... | 1991 | 1783607 |
| comparative aspects of microsomal cytochrome p-450-dependent monooxygenase activities in musk shrew (suncus murinus), mongolian gerbil (meriones unguiculatus), harvest mouse (micromys minutus) and rat. | 1. the cytochrome p-450 content (0.75 +/- 0.13 nmol/mg microsomal protein) in musk shrew (suncus, suncus murinus) liver microsomes was lower than that (1.30 +/- 0.26) in rat liver microsomes, but it is approximately the same level as in the mongolian gerbil (meriones unguiculatus, 1.18 +/- 0.14), harvest mouse (micromys minutus, 1.11 +/- 0.02) and rat. 2. the hydroxylation activity (based on cytochrome p-450) of medium-chain fatty acids (otanoic, decanoic, lauric and tridecanoic acids) is much h ... | 1991 | 1799966 |
| serotonergic ligand binding in aging brain of experimental animals. | although the use of aging experimental animals for studying serotonergic neuronal changes is limited because of species differences, cholinergic neuronal deterioration does appear to be a feature common to mammalian aging brains. in the present study, a recently introduced experimental animal, suncus murinus (house musk shrew, an insectivore classified as being at the stem of the mammalian phylogenic tree) which in certain physiological characteristics is more closely related to the primate than ... | 1991 | 1833658 |
| induction of fatty liver by fasting in suncus. | we found that a fatty liver was easily induced in a novel experimental animal, suncus murinus (suncus), by withholding food. hepatic triglyceride content increased linearly for up to 24 h after fasting in these animals. serum levels of neutral lipids are very low in the fed state compared with those in rats, and decreased significantly after 24 h fasting. on the other hand, serum free fatty acids, which are at the same level in fed animals as in rats, increased threefold in the fasting suncus. i ... | 1991 | 1940621 |
| a comparative electron microscopic analysis of mechanoreceptors in the hard palate of the mouse (mus musculus; rodentia) and the musk shrew (suncus murinus; insectivora). | these mechanoreceptors were studied with particular regard to their type and the distribution. in both species they were concentrated in the crests of transverse palatine rugae. in the mouse, meissner corpuscles, glomerular corpuscles, and merkel cell nerve endings were seen in every palatine ruga, though the first antemolar ruga also contained simple and atypical lamellated corpuscles. in contrast, the palatine rugae of the musk shrew contained only simple corpuscles and merkel cell nerve endin ... | 1990 | 2076060 |
| localization of motoneurons innervating the stylohyoid muscle in the monkey, cat, rabbit, rat and shrew. | the distribution of motoneurons innervating the stylohyoid muscle was examined in the japanese monkey (macaca juscata), cat, rabbit, rat and house musk shrew (suncus murinus) using the retrograde tracing method of horseradish peroxidase. the enzyme was injected into the stylohyoid muscle after ligating the central cut ends of the main peripheral branches of the facial nerve supplying the superficial facial muscles, or the trunk of the glossopharyngeal nerve supplying the pharyngeal muscles. in t ... | 1990 | 2092061 |
| group a rotavirus infection in animals from an animal house and in wild-caught monkeys. | randomly selected samples from different animal colonies from two laboratory animal houses and from the wild-caught monkeys were tested for the presence of anti-rotavirus antibodies to estimate the rates of infection with group a rotavirus. antibodies to the common group a rotaviral antigen were detected by a competitive enzyme-linked immunosorbent assay (elisa) using reagents of who elisa rotavirus detection kit. the results of the study showed that white mice, albino rats, and guinea pigs from ... | 1990 | 2122998 |
| an immunohistochemical study on the distribution of endocrine cells in the gastrointestinal tract of the musk shrew, suncus murinus. | the endocrine cells in the gastrointestinal tract of the musk shrew were studied immunohistochemically. eleven kinds of endocrine cells, immunoreactive for serotonin, somatostatin, gastrin, cholecistokinin, gastric inhibitory polypeptide, motilin, secretin, neurotensin, pancreatic glucagon, enteroglucagon and bovine pancreatic polypeptide, were revealed. in the stomach, serotonin-, somatostatin-, gastrin-, pancreatic glucagon- and enteroglucagon-immunoreactive cells were detected. the first thre ... | 1990 | 2134360 |
| deficiency of beta-adrenoceptor-mediated relaxation in suncus trachea. | characteristics of beta-adrenoceptor in the tracheal smooth muscle of suncus murinus (suncus) were studied in comparison with those of rats and guinea pigs. isoproterenol induced concentration-dependent relaxation of suncus trachea. however, the maximal relaxation was very small, and about 1000 times higher concentration was necessary compared to the case of the guinea pig. the order of the sensitivity to isoproterenol and the maximal relaxation was guinea pig much greater than rat greater than ... | 1990 | 2155338 |
| antibodies raised against different oligopeptide segments of human dopamine-beta-hydroxylase. | we raised antibodies against 3 oligopeptide segments of human dopamine-beta-hydroxylase (hdbh) corresponding to the n-terminal (hdbh-n), the intermediate (hdbh-i), and the c-terminal (hdbh-c) amino acid sequences (residues 26-43, 452-468, and 582-598), respectively. we characterized the antibodies in terms of specificity by means of western blotting and immunohistochemistry. anti-hdbh-n antiserum recognized dbh in the brain (noradrenergic neurons in the pons and medulla oblongata) and adrenal me ... | 1990 | 2293101 |
| serum concentrations of thyroid hormones and activity of iodothyronine deiodinase in peripheral tissues of the house musk shrew, suncus murinus. | serum concentrations of thyroid hormones and the properties of iodothyronine deiodinase in tissues of the house musk shrew, suncus murinus, were examined and compared with those of the rat. serum concentrations of thyroxine (t4) and 3,3',5'-tri-iodothyronine (rt3) were higher, while the serum concentration of 3,5,3'-tri-iodothyronine (t3) was lower in the shrew than in the rat. among liver, kidney, skeletal muscle, heart, brown adipose tissue (bat), spleen, lung, testes and thymus homogenates of ... | 1990 | 2338528 |
| genetic relationship among the musk shrews, suncus murinus insectivora, inhabiting islands and the continent based on mitochondrial dna types. | cleavage patterns of mitochondrial dna (mtdna) by restriction endonucleases were examined in musk shrews collected at six trapping sites on two japanese and two indonesian islands, on sri lanka, situated close to the indian subcontinent, and on the mainland of east bengal in bangladesh. no variation of mtdnas was found among the japanese and indonesian shrews, despite their geographical isolation by the sera. in contrast, at least six mtdna types were present in the sri lanka and the bangladesh ... | 1990 | 2383245 |
| biochemical and immunological characterization of suncus murinus mammary tumor virus dna polymerase. | enzymological properties of the rna-directed dna polymerase associated with the suncus murinus mammary tumor virus (sm-mtv) was investigated and its antigenic relatedness to other retroviral dna polymerases was examined. the enzyme exhibited higher activity in the presence of mg2+ than in the presence of mn2+ with endogenous rna as well as with almost all of the synthetic template x primers tested. mg2+ was also effective with poly(2'-o-methylcytidylate) x oligodeoxyguanylate which was known to ... | 1986 | 2417416 |
| ultrastructural characterization of the retrovirus particles (sm-mtv) liberated from the mammary tumor cell line (sm-mt) of a house musk shrew, suncus murinus (insectivora). | detailed ultrastructure of a new type of retrovirus (sm-mtv) released by cultured cells (sm-mt) of a spontaneous mammary tumor from a house musk shrew suncus murinus, insectivora, is described. the virus particles were revealed as three forms: intracellular; budding; and extracellular. the intracellular type a particles were similar in profile to those associated with mouse mammary tumor cells and tended to form a small cluster of several particles in the cytoplasm. in addition, horseshoe-shaped ... | 1986 | 2421890 |
| major structural polypeptides of retrovirus produced by a suncus murinus mammary tumor cell line and type d retrovirus share interspecies antigenic determinants. | constitutive polypeptides of retrovirus produced by a suncus murinus mammary tumor cell line (sm-mtv) were characterized by immunofluorescence and immunoblotting. the major structural polypeptide of sm-mtv, molecular weight 44/43k, immunologically cross reacted with the structural polypeptides of mason-pfizer monkey virus (mpmv) (molecular weights 27k and 12/10k). sm-mtv constitutive polypeptides did not show antigenic relatedness with those of the following mammalian retroviruses: murine mammar ... | 1988 | 2460996 |
| nucleotide sequence of suncus murinus immunoglobulin mu gene and comparison with mouse and human mu genes. | both primates and rodents apparently originated from insectivores and then evolved separately. we isolated the immunoglobulin mu gene from dna of the insectivore suncus murinus and determined its nucleotide sequence. the gene organization was ch1 exon (318 bp)-intron (89 bp)-ch2 exon (345 bp)-intron (80 bp)-ch3 exon (318 bp)-intron (85 bp)-ch4 exon (392 bp)-coding sequence and 3'-untranslated region. comparison of nucleotide sequences of mu genes between mouse, human and suncus murinus indicated ... | 1989 | 2497033 |
| characterization of three forms of cytochrome p-450 inducible by 3-methylcholanthrene in golden hamster livers with special reference to aflatoxin b1 activation. | three forms of cytochrome p-450 of liver microsomes of 3-methylcholanthrene-treated golden hamsters were purified and characterized as regards their catalytic activity toward aflatoxin b1-related hepatocarcinogenic mycotoxins. these include two major forms, designated as cytochrome p-450-afb (p-450-i) and p-450-ii, and one minor form, p-450-iii. cytochromes p-450-afb, p-450-ii, and p-450-iii have their absorption maximum in the carbon monoxide-complex of the reduced form at 448.5, 447.0, and 448 ... | 1989 | 2509440 |
| [three dimensional structure of the connective tissue papillae of the tongue in suncus murinus]. | the surface structure of the connective tissue papillae (cp) of suncus murinus tongue was observed by sem after fixing with karnovsky's fixative and removal of the epithelial cell layer with 3n or 8n hcl. on the surface of the slender conical tongue, there are densely distributed filiform papillae among which fungiform papillae are seen sporadically. a pair of vallate papillae are situated in the posterior region of the tongue. filiform papillae appear somewhat different externally depending on ... | 1989 | 2519278 |
| scanning, transmission and immunoelectron microscopical studies of the tonsil-like lymphoid organ of normal and horseradish-peroxidase-injected laboratory suncuses. | fine structures of normal and horseradish peroxidase (hrp)-stimulated tonsil-like lymphoid organs of the laboratory suncus (suncus murinus) were examined by scanning, transmission and immunoelectron microscopies. the normal organs appear as a pair of small oval protrusions at the upper lateral sites of the fauces, and consist of a single lymph nodule with a germinal center and a crypt-like epithelium with prominent lymphoid cell infiltration. postcapillary venules (pcv) and efferent lymphatics a ... | 1989 | 2603630 |
| the intermediate epithelium lining the larynx of the suncus murinus. | in the larynx of the suncus murinus the stratified squamous epithelium lines the tip of the caudal surface of the epiglottis and the region close to the vocal process of the arytenoid cartilage, while the ciliated columnar epithelium is located in the laryngeal sac and the dorsal part of the vocal fold. further, in the transitional zone between the stratified squamous epithelium and the ciliated columnar one there exists the epithelium which shows gradations ranging from stratified squamous thro ... | 1989 | 2608258 |
| chigger mite infestation of small mammals in a feral biotope of a public park area of south delhi. | examination of bandicota bengalensis (8) and suncus murinus (4) trapped in a feral biotope of a public park area of south delhi revealed presence of the known scrub typhus vector leptotrombidium (l.) deliense, the suspected vector gahrliepia (s.) ligula and gahrliepia (walchia) sp. of chigger mites, on them. the epidemiologically important population indices (chigger infestation rate-cir and incidence rate--1r) were estimated. the overall cir of the three mite species on the hosts was 2.83 mite/ ... | 1989 | 2638383 |
| major ocular glands (harderian gland and lacrimal gland) of the musk shrew (suncus murinus) with a review on the comparative anatomy and histology of the mammalian lacrimal glands. | the harderian gland of the musk shrew suncus murinus is elongated anteroposteriorly from in front of the eye to behind the ear. the gland is divided into two portions: an anterior portion (a portion) and a posterior portion (p portion). the single secretory duct of the gland emerges from the anterior end of the p portion, receives several secretory ducts of the a portion during the course along it, runs around the ventral aspect of the eyeball, and finally opens into the anterior corner of conju ... | 1989 | 2664187 |
| isolation and characterization of shrew (suncus murinus) liver alcohol dehydrogenases. | 1. starch gel electrophoresis of adult shrew (suncus murinus) liver extracts revealed five forms of alcohol dehydrogenase (adh 1-5) and four of them were purified. 2. adh-4 and adh-5 resemble human class i adh in terms of electrophoretic mobility, substrate specificity and sensitivity to pyrazole inhibition. 3. adh-2 does not belong to any of the three classes of human adhs but rather with catalytic properties similar to those of the class b adh found in guinea pig liver. 4. adh-1 prefers second ... | 1989 | 2666017 |
| ultrastructure of secretory ameloblasts in the house musk shrew, suncus murinus, insectivora. | tooth germs from neonatal house musk shrews, suncus murinus, were used for the study. the tooth morphogenesis was compared electron microscopically to that of primates. in the tooth germ at the bell stage, the ameloblast was 3 x 50 microns in size, columnar in shape and had several tubular-type golgi apparatus which were at the distal end of the cell. most mitochondria were noted at the proximal end of ameloblasts. tomes' processes were 1 micron in width, protruded 10 microns from the ameloblast ... | 1989 | 2718719 |
| suncus murinus. observations on ecology, distribution, status to plague in bombay. | the common house shrew suncus murinus has been shown to play an important role in maintenance and perpetuation of plague infection by earlier plague workers. with the control of human plague there is no knowledge about foci of plague in small mammals associated with man. present study was carried out to fill in this lacuna. studies carried out in the present paper reveal that s. murinus does not harbour any plague infection in bombay. this species is widely distributed in bombay and is found to ... | 1989 | 2723422 |
| comparative studies on the stereo architecture of the connective tissue papillae in some mammalian tongues. | the epithelial cell layer was removed from the underlying connective tissue papillae by the method of long term hydrochloric acid treatment and the connective tissue surface was observed by scanning electron microscopy. tongues of insectivora (suncus murinus), rodentia (mouse, rat, guinea pig), carnivores (dog, cat) and primates (man) were studied. each animal species had proper architecture of connective tissue papillae as to four types of lingual papillae. there was a tendency for the stereo s ... | 1989 | 2748642 |
| organ distribution, purification and characterization of kynureninase in suncus murinus (insectivora) and anthranilic acid level in the serum. | 1. the highest kynureninase activity was measured in suncus liver compared with other organs tested. the holo-enzyme activity detected in liver was 25%. 2. the enzyme mainly localized in liver cytosol was purified to a single protein band by heat treatment, ammonium sulfate fractionation, deae-sepharose, hydroxyapatite and phenyl-sepharose column chromatography. 3. the purified enzyme was effective for both kynurenine and 3-hydroxykynurenine, and showed the optimum ph at 8.5 against both substra ... | 1989 | 2752727 |
| effect of castration on epididymal sperm storage in male musk shrews (suncus murinus) and mice (mus musculus). | reproductively mature male musk shrews and mice were bilaterally castrated. epididymal sperm numbers and motility were assessed 0, 2, 4 and 6 weeks after surgery. seminal vesicle weights and plasma concentrations of total androgens were also measured. in male musk shrews, 30% of the original epididymal sperm numbers were still present 2 weeks after castration and motile spermatozoa were present in 2 of 7 individuals. by 4 and 6 weeks after castration the numbers of spermatozoa remaining declined ... | 1989 | 2754641 |
| structural and functional analysis of long terminal repeats of suncus murinus mammary tumor virus. | a 2.7-kilobase (kb) cdna sequence complementary to suncus murinus mammary tumor virus (sm-mtv) genomic rna [corrected] was prepared using purified virions produced by the sm-mt cell line, which had been established from a spontaneous mammary tumor of s. murinus. it was found, by using this cdna in southern hybridization experiments, that sm-mtv was endogenous to this animal and that some 50 copies of endogenous provirus were present per haploid cellular genome. in addition, a proviral sm-mtv dna ... | 1988 | 2831384 |
| characteristics of cardiac beta-adrenoceptors in suncus murinus. | | 1988 | 2854498 |
| isolation of haemorrhagic fever with renal syndrome virus from suncus murinus, an insectivore. | | 1985 | 2857871 |
| serum constituents and liver photomicrographs of wild suncus murinus in the south of taiwan. | serum constituents and liver of the wild male suncus as well as of those bred and fed in our laboratory were examined serologically and histologically. the following results were obtained: the serum glutamic-oxaloacetic transaminase, gamma-glutamyl transaminase, inorganic phosphate, blood urea nitrogen, creatinine, uric acid, and zinc turbidity test levels of wild suncus were higher than those of 4 and 8 week old fed suncus. the total cholesterol level of wild suncus was lower than those of 4 an ... | 1987 | 2880742 |
| cats--source of protection or infection? a case-control study of hemorrhagic fever with renal syndrome. | in the first case-control study analyzing risk factors in sporadic hemorrhagic fever with renal syndrome, 111 cases occurring in shanghai in 1983 and 1984 and 136 matched controls were studied. three factors were associated with risk of disease: travel in the month before onset of illness, intense exposure to rodents in the home, and cat ownership. risk associated with cat ownership was not confounded by exposure to rodents in the home. neither cat ownership nor risk associated with rodent expos ... | 1987 | 2889355 |
| characterization of mixed-function oxidases and purified cytochrome p-450 of livers of house musk shrew, suncus murinus. | characteristics of mixed-function oxidases in the liver of house musk shrew, suncus murinus, were studied. the basal level of cytochrome p-450 and the activity of drug-metabolizing enzyme in hepatic microsomes of suncus murinus is relatively lower than that of rats, while the level of cytochrome b5 and nadph-cytochrome c reductase is approximately the same as that of rats. the treatment of suncus murinus with phenobarbital and 3-methylcholanthrene elevated the level of cytochrome p-450 and the a ... | 1988 | 2894946 |
| side gland of suncus murinus as a new model of sebaceous gland: 5 alpha-reductase, androgen receptor, and nuclear androgen content in male and female animals. | the side gland of suncus murinus is composed of well-developed sebaceous glands in both males and females. we measured the 5 alpha-reductase activity, androgen receptor content, and the intranuclear concentrations of testosterone and dihydrotestosterone in this side gland taking it as a new experimental model of human sebaceous glands. lineweaver-burk plot analysis suggested the presence of two classes of 5 alpha-reductase with different km for testosterone in the homogenate. the enzyme activity ... | 1989 | 2919895 |
| studies on shrew (suncus murinus) epidermal growth factor. | the shrew smg contains a very high level of egf. by heterologous radioreceptor assay, the egf content was determined to be about 300 pmol/mg wet weight in the male. the content is sex dependent; in the female gland, it is only 4% of the male gland level. egf level and egf receptor content in other tissues showed a reciprocal distribution pattern with the parotid gland containing the second highest level of egf and the liver containing the largest amount of egf receptor. shrew egf is heat stable. ... | 1986 | 3008480 |
| preparation and characterization of monoclonal antibodies against a form of hamster liver cytochrome p-450 highly specific to aflatoxin b1. | monoclonal antibodies were prepared against a form of cytochrome p-450 (designated as cytochrome p-450-i) purified from 3-methylcholanthrene-treated hamster livers which is highly specific to aflatoxin b1. the cytochrome p-450-i was detected in elisa and western blots in liver microsomes from 3-methylcholanthrene-treated hamsters and also from non-treated and phenobarbital-treated hamsters in smaller amounts. however, none of the liver microsomes from 3-methylcholanthrene-treated rat, rabbit, gu ... | 1988 | 3132167 |
| observations on commensal rats and their status to plague in bombay. | the distribution pattern of various types of commensal rodents in bombay city reveals that bandicota bengalensis constitutes the predominant commensal rodent species followed by r. rattus and rattus norvegicus. apart from these three types, bandicota indica, m. musculus and an insectivore (suncus murinus) are the three species of commensal small mammals that are frequently encountered in or near human habitations. these small mammals are prevalent throughout the year and their percentage distrib ... | 1988 | 3221091 |
| unique features of secretory granules observed in the pituitary growth hormone-secreting (gh) cells of the musk shrew (suncus murinus l). | unique rod-shaped secretory granules were observed among oval or spherical secretory granules in gh cells of the anterior pituitary gland of musk shrew using the protein a-gold procedure combined with electron microscopy. the rod-shaped and spherical secretory granules were both immunoreactive by the immuno-gold method using antiserum to sheep gh. the rod-shaped secretory granules, which seem to be formed directly from the golgi vesicles, extend from several hundred to several thousand nm in len ... | 1988 | 3342430 |
| isolation of mycoplasmas from house musk shrews (suncus murinus). | mycoplasmas were isolated from various sites of experimental and wild house musk shrews (suncus murinus). the oral cavity was the most prominent site to harbor mycoplasmas (15/18; 83%), followed by the nasal cavity (9/18; 50%). all of the isolated strains required serum for their growth and all fermented glucose. they were found to be serologically homogeneous by growth inhibition test but did not cross-react with several type strains of mycoplasma or reference strains of murine, feline, canine, ... | 1988 | 3416940 |
| detection of lymphocytic choriomeningitis virus antibody in colonies of laboratory animals in japan. | indirect fluorescent antibody method was applied for a detection of lymphocytic choriomeningitis virus (lcmv) antibody in colonies of laboratory animals in japan. the results showed that the antibody exist in spf mice (3/152, 2.2%) and conventional mice (30/539, 5.6%) with the titers ranging from 1:10 to 1:160. the antibody was also detected in 2.2% (2/89) of syrian hamsters, and 2.9% (2/68) of apodemus agrarius, 21.4% (3/14) of japanese harvest mice which have been maintained as laboratory colo ... | 1986 | 3525200 |
| a new experimental animal for the study of age-related changes in serotonergic neuronal activity in the brain cortex. | calcium uptake by the cortical synaptosomes in a rodent (fischer rat) and an insectivore shrew (suncus murinus) was detected as a parameter reflecting molecular dysfunction of the aging brain. the change in calcium uptake by the cortical synaptosomes in both species was concomitant which showed less than half the capacity at 24 months old animals compared with those at 8 months old. on the other hand, 5-hydroxytryptamine binding and imipramine binding to the membrane fraction of aging rat brain ... | 1987 | 3574597 |
| morphological and reproductive characteristics of musk shrews (suncus murinus) collected in bangladesh, and development of the laboratory line (ban line) derived from them. | to establish a unique laboratory line of the musk shrew with different genetic properties from previously developed laboratory lines, 49 male and 49 female shrews were captured in the campus of bangladesh agricultural university from october through november in 1983 and from december in 1985 to january in 1986. the shrews collected were of various ages. they had light gray coats, with slight variations in color. except for the 12 shrews introduced into our laboratory, the total length and body w ... | 1987 | 3678369 |
| ouabain susceptibility of heart muscle of the house musk shrew, an insectivore: a comparison with the rat, guinea pig and rhesus monkey. | the susceptibility to ouabain of the heart muscle of the house musk shrew (suncus murinus), an insectivore, was investigated by means of in vitro experimentation, and compared with the rat, guinea pig, and rhesus monkey. contraction of the electrically driven heart muscles of all species slowly increased following application of ouabain. the shrew was approximate 100-fold more sensitive than the rat and 10-fold less than the guinea pig and rhesus monkey. only the rat heart preparation that was a ... | 1987 | 3694428 |
| anatomy and histology of the musk shrew (suncus murinus) prostate. | gross anatomy and the light and electron microscopic characteristics of the musk shrew (suncus murinus, insectivora) prostate are described. the prostate is a pair of compound tubuloalveolar glands with one main excretory duct for each gland. each gland is divided into ventral and dorsal lobes. the tubuloalveoli are larger in diameter and the secretory cells are lower in the ventral than in the dorsal lobes. probable spontaneous release of secretory granules and accumulation of secretory materia ... | 1986 | 3703747 |
| serum constituents of suncus murinus. | blood samples were collected by cardiac puncture from nine-week-old suncus, mice and rats those had been fasted for 16 hours, and the serum was assayed for the levels of corticosterone, cortisol, and other constituents. the following results were obtained: the serum levels of corticosterone and cortisol and corticosterone/cortisol ratio of suncus were about the same as those of human. the sgpt, gamma-gt, alp, ldh, ca and k values in suncus were all within the normal range of the respective value ... | 1986 | 3709676 |
| acute hepatotoxicity induced by hepatotoxins in suncus murinus. | a comparative study was conducted to contrast the hepatotoxicity of several chemicals in the musk shrew (suncus murinus) versus other common laboratory species (mouse or rat), and the following results were obtained from serum enzymes (sgot and sgpt) and histopathological findings of liver specimens. the sensitivity of suncus liver to ccl4 was different from that of mouse liver. the sensitivity of suncus liver to beta-d-galactosamine was weaker than that of rat liver. the sensitivity of suncus l ... | 1986 | 3735458 |
| a new retrovirus produced by tissue culture cell line from mammary tumor of a house musk shrew, suncus murinus. | a new type of retrovirus (sm-mtv) released by cultured cells of a spontaneous mammary tumor from a house musk shrew, suncus murinus, is described. the sm-mtv is distinct morphologically from type c particles. in spite of certain morphological similarities to type b and type d retroviruses, the sm-mtv is readily distinguishable. the extracellular virions had a spikeless envelope containing a centrally located nucleoid with a small electron-dense core surrounded by an inner membrane. the budding p ... | 1985 | 4060590 |
| pituitary luteinizing hormone level in the male house musk shrew, suncus murinus l., following castration and testosterone treatment. | the effect of castration and replacement therapy with testosterone propionate (tp) on the pituitary lh concentration and contents in the house musk shrew was investigated by using an in vitro bioassay for lh, the rat interstitial cell testosterone assay. the concentration and contents of lh increased slightly 10 days after castration, but decreased progressively thereafter to about a half of the pre-operation level by 90 days after the operation. the replacement with tp (100 micrograms/day) for ... | 1985 | 4085414 |
| a serological survey of rodent plague in taiwan and offshore islands. | serological surveys were made on individual sera of small animals trapped on taiwan and offshore islands. the animals were shrews of the species suncus murinus, and rats of the species rattus rattus and r. norvegicus. the tests showed that on makung in the peng-hu islands (pescadores), 66% of the shrews, 30% of the r. rattus and 15% of the r. norvegicus had passive haemagglutination titres with fraction 1 antigens in the range of 1:16 to 1:256, indicative of previous plague infections. these obs ... | 1968 | 5303332 |
| preliminary studies on experimental transmission of kyasanur forest disease virus by nymphs of ixodes petauristae warburton, 1933, infected as larvae on suncus murinus and rattus blanfordi. | | 1968 | 5679151 |
| [life cycle of seuratum nguyenvanaii, le-van-hoa, 1964, parasite of the shrew-mouse, suncus murinus (l.) in vietnam. (preliminary note)]. | | 1966 | 6012572 |
| ecology of plague in vietnam. i. role of suncus murinus. | | 1967 | 6024813 |
| hemagglutination-inhibiting antibody in hemorrhagic fever with renal syndrome. | hemagglutination activity was demonstrated in a hantaan virus antigen prepared from infected suckling mouse brain by sucrose-acetone extraction. hemagglutination of goose erythrocytes was ph dependent and was optimal at ph 6.0-6.2. immunofluorescent and hemagglutination-inhibiting antibodies were significantly correlated in 80 human and 13 animal sera. hemagglutination-inhibiting antibody was present in some patients 20 years after the onset of hemorrhagic fever with renal syndrome. the hemagglu ... | 1984 | 6150063 |
| the reaction of funambulus tristriatus tristriatus rattus blanfordi and suncus murinus to kyasanur forest disease virus. | | 1981 | 6273309 |
| susceptibility of cynopterus sphinx (frugivorus bat) & suncus murinus (house shrew) to japanese encephalitis virus. | | 1984 | 6327512 |
| comparative cytoarchitectonic study of gudden's tegmental nuclei in some mammals. | the structure and location of the dorsal and ventral tegmental nuclei of gudden were studied in brains of 12 species of mammals. the ventral tegmental nucleus of gudden is composed of oval or polygonal, medium-sized, well-stained cells, and includes the pars principalis situated ventral to the fasciculus longitudinalis medialis, and the pars suprafascicularis in the central gray matter dorsal to the fasciculus longitudinalis medialis (in the golden hamster, mouse, vole, and house shrew). the dor ... | 1983 | 6345599 |
| comparative anatomical study of the tegmentomammillary projections in some mammals: a horseradish peroxidase study. | mammillary projections from each subnuclei of gudden 's tegmental nuclei were investigated by retrograde transport of horseradish peroxidase (hrp) in the cat, rat, guinea pig, golden hamster and house shrew (suncus murinus, insectivora). the dorsal tegmental nucleus of gudden (td) is composed of the pars dorsalis (tdd) and the pars ventralis ( tdv ) in the cat, rat, guinea pig, and golden hamster, but the td of the house shrew can not be divided. the ventral tegmental nucleus of gudden (tv) is c ... | 1984 | 6428701 |
| mesostigmatid mites associated with the house shrew, suncus murinus, in rangoon, burma. | in rangoon and vicinity suncus murinus comprises almost 20% of the small mammal population with almost equal load of mesostigmatid mites compared to murine rodents. suncus murinus was infected by four species of laelapids, out of which l. myonyssognathus seems to infest more on urban s. murinus. the infestation of the free living androlaelaps or hypoaspis species is higher on the rural shrews while the cheyletus species is higher on the urban than the rural s. murinus. | 1980 | 6452696 |
| tick-borne rickettsioses in pune district, maharashtra, india. | an extensive study on tick-borne rickettsioses in the pune district of maharashtra revealed that indian tick typhus exists as a zoonosis, which only occasionally causes disease in man. by sero-conversion in guinea pigs, presumptive isolates of rickettsia conori and coxiella burnetii were recovered from 4 of the 11 species of ticks examined. boophilus microplus and rhipicephalus haemaphysalis were found to be harbouring r. conori whereas c. burnetii was isolated from haemaphysalis intermedia and ... | 1984 | 6500861 |
| the occurrence of salmonellae in house shrews and rats in ipoh, malaysia. | house shrews (suncus murinus) and rats (rattus rattus diardii), trapped during a survey period from july 1978 to december 1979 and thereafter on a random basis, from residences within and outside the veterinary research institute, ipoh, malaysia campus, were bacteriologically examined for the presence of salmonellae. of the 55 shrews and 8 rats examined, 39 (71%) shrews and 2 (25%) rats were found positive. there were 46 salmonella isolates which included 5 dual infections. these were serotyped ... | 1984 | 6523172 |
| genetic polymorphism of the vitamin d binding protein (gc) in the musk shrew (suncus murinus). | in the musk shrew (suncus murinus), the electrophoretic bands in the post-albumin region were identified as vitamin d binding protein (gc) by the [3h] vitamin d3 binding method. three gc phenotypes were distinguished from each other: a single faster band (gc-a), a single slower band (gc-b) and the double bands (gc-ab). results of mating experiments indicated that the gc-a and gc-b are controlled by two codominant alleles, gca and gcb at an autosomal locus (gc), respectively. it was noticed that, ... | 1984 | 6547578 |
| some observations on the structure of suncus liver with special reference to the vitamin a-storing cell. | the structure of the liver of the thick-tailed shrew (suncus murinus) was studied with special reference to the vitamin a-storing cell. the macroscopic arrangement of hepatic lobes was the same as those of rodents. connective tissues of glisson's sheath were not prominent. there were gradual differences in the size and the cytoplasmic contents of hepatocytes among perihepatic, intermediate, and periportal regions. these correspond to the acinar zones 3, 2, and 1 of rappaport, respectively. the u ... | 1983 | 6613904 |
| cytochrome p-450-dependent fatty acid hydroxylase system in japanese house musk shrew, suncus murinus. | the substrate specificity and other properties of a fatty acid hydroxylase system in liver microsomes of the japanese house musk shrew, suncus murinus, were examined. shrew liver microsomes catalyzed the hydroxylation of various saturated fatty acids (c8-c18) to the corresponding omega- and (omega-1)-hydroxy derivatives. the relative activities of the hydroxylase with these substrates were as follows: c12 (100, actual conversion: 7.05 nmol/mg of microsomal protein/min), c10 (90), c14 (87), c16 ( ... | 1984 | 6725235 |
| [length and weight of gastrointestinal tracts of pikas, suncus, millardias, mice and rats]. | the length and weight of gastrointestinal tracts including contents of ten week old male pikas (ochotona rufescens rufescens) and suncus (suncus murinus) were measured and they were investigated and compared with those of millardias, icr-mice and wistar-rats. the length from the duodenum to the anus of pikas was much longer and the weight from the stomach to the anus was about 16g per 100g of body weight. the weight of cecum was about 7g per body weight and they were heavier than those of other ... | 1983 | 6852120 |
| population indices of chiggers (leptotrombidium deliense) and incidence of scrub typhus in chinese military personnel, pescadores islands of taiwan, 1976-77. | larval leptotrombidium deliense were recovered from live-trapped suncus murinus, rattus rattus and r. norvegicus captured in the pescadores islands of taiwan during 1976 and 1977. weekly and monthly indices of chigger infestation expressed as a percentage of hosts infested and the number of chiggers per host for s. murinus and rattus spp. were calculated. close correlations were observed between monthly indices of l. deliense measured for s. murinus and rattus spp. and the number of laboratory-c ... | 1982 | 7080163 |
| taste preferences for amino acids in the house musk shrew, suncus murinus. | taste preferences in house musk shrews for amino acids as well as nacl, sucrose, quinine hydrochloride, hcl and saccharin na were studied by employing the two-bottle preference technique. shrews showed a preference for 0.2--05. m sucrose but a moderate rejection to nacl and a strong rejection to quinine, hcl and saccharin. they exhibited a marked preference for many naturally occurring l-alpha-amino acids with aliphatic side chains at both 0.02 and 0.2 m. increase in the aliphatic side chain len ... | 1982 | 7100283 |
| the primary structure of adult hemoglobin of musk shrew (suncus murinus). | an alpha chain and two beta chains beta i and beta ii) were obtained from adult hemoglobin of the musk shrew (suncus murinus) by cm-cellulose column chromatography. the s-carboxymethylated alpha chain and the s-aminoethylated beta chains were each digested with trypsin and the amino acid sequences of the tryptic peptides obtained were established. the ordering of these peptides in the alpha and beta chains was deduced from their homology with the primary structures of the alpha and beta chains o ... | 1981 | 7309005 |
| a study of small mammals in the ciloto field station area, west java, indonesia, with special reference to vectors of plague and scrub typhus. | from june 1977 to june 1978 a study of smal mammals was carried out in the ciloto field station area, west java, indonesia by the who vector biology and control research unit-ii. the objectives of the investigations were to determine the diversity and density of rodent species, to find potential plague and scrub typhus vectors and to study their host-parasite relationships. in the 13 month period a total of 6 species of murids were identified; two species of campestral rats (r. tiomanicus and r. ... | 1980 | 7403957 |
| rodent and scrub typhus survey in a ricefield at kramat tunngak area, tanjung priok, jakarta, indonesia. | trapping of small mammals in a ricefield at kramat tunggak around tanjung priok in jakarta city, was carried out from july 1977 through june 1978. of three species of rodents, r.argentiventer was found to be the predominant species in the ricefield. r.r.diardii was an intermittent resident, and the presence of r.norvegicus was interesting observation. s.murinus, a house shrew, was also present. r.argentiventer was the dominant species during the periods when the rice grains were available as a s ... | 1980 | 7434074 |
| evidence for the lack of hepatic n-acetyltransferase in suncus (suncus murinus). | the abilities of liver cytosol fractions from the suncus and sprague-dawley (sd) rats to n-acetylate aniline, p-aminobenzoic acid, p-aminosalicylic acid and 2-aminofluorene (af) were compared. the cytosol from rats n-acetylated these substrates at efficient rates, whereas the cytosol from the suncus did not n-acetylate these substrates at detectable rates. when af was given to the suncus, 2-acetylaminofluorene (aaf), a metabolite of af formed by n-acetyltransferase (nat), was not detectable in s ... | 1995 | 7488230 |
| collagen fibrils in the odontoblast layer in the teeth of the rat and the house shrew, suncus murinus, by scanning electron microscopy using a maceration method. | it is not well known whether there are gaps in the tight junctions between odontoblasts and whether the fluid flows from the pulp to the predentin through these gaps. the collagen fibrils in the odontoblast layer were investigated using a maceration method in order to show the existence of the gaps between tight junctions of the odontoblasts. the mandibles containing teeth of the rat and the house shrew were digested by naoh maceration and revealed the architecture of the collagen fibrils under ... | 1995 | 7554943 |
| characterization of a novel brain neutral glycosphingolipid composition in house musk shrew (suncus murinus). | glycosphingolipids were extracted from the brain of house musk shrew (suncus murinus). neutral glycosphingolipids were purified by qae-sephadex column chromatography followed by high-performance liquid chromatography using an iatrobeads column. purified glycosphingolipids were identified by high-performance thin-layer chromatography, carbohydrate analysis, fast-atom bombardment mass spectrometry and tlc immunostaining. the ganglioside pattern was almost the same as the pattern obtained for rat b ... | 1995 | 7601161 |
| immunocytochemical identification of serotonergic supraependymal nerve fibers in the third ventricle of the house musk shrew, suncus murinus. | supraependymal fibers of the house musk shrew (suncus murinus) were examined by conventional scanning electron microscopy (sem), backscattered electron (bse) imaging of enzyme immunohistochemistry and by immunotransmission electron microscopy in the dorsal part of the third ventricular wall. in this region, ependymal cells were not so heavily ciliated and conventional sem studies showed two main categories of supraependymal fibers. the first type consisted of long fibers fasciculated which were ... | 1995 | 7625602 |
| distribution of chicken-ii gonadotropin-releasing hormone in mammalian brain. | brains of nonmammalian vertebrates typically contain multiple forms of gonadotropin-releasing hormone (gnrh). until recently, only the mammalian form of gnrh (mgnrh) had been isolated in placental mammals. biochemical and histological data show that both mgnrh and chicken-ii gnrh (cgnrh-ii) are present in a primitive placental mammal, the musk shrew (suncus murinus). similar to the case in nonmammalian species, in the musk shrew, neurons that express cgnrh-ii are located in a discrete cluster in ... | 1995 | 7673483 |
| identification of chicken gnrh ii in brains of metatherian and early-evolved eutherian species of mammals. | two molecular forms of gnrh (chicken gnrh ii and a second variant) are present in the brains of species from all the major vertebrate groups. in mammals, two forms are present in metatherian species and early-evolved eutherian species, but chicken gnrh ii has not been identified in more advanced eutherian species. we investigated the nature of gnrh molecular forms in several early-evolved mammalian species, using high performance liquid chromatography and radioimmunoassay with specific gnrh anti ... | 1994 | 7716279 |
| a novel dodecadepsipeptide, cereulide, is an emetic toxin of bacillus cereus. | a vacuole-formation substance, cereulide of bacillus cereus, is an emetic toxin in animals. both oral administration and intraperitoneal injection of cereulide caused dose-dependent emesis in suncus murinus, a new animal model of emesis. vagotomy or a 5-ht3 receptor antagonist completely abolished this emetic effect. therefore, cereulide causes emesis through the 5-ht3 receptor and stimulation of the vagus afferent. we also found that our purified cereulide caused swelling of mitochondria of hep ... | 1995 | 7781985 |
| evolution of alanine:glyoxylate aminotransferase 1 peroxisomal and mitochondrial targeting. a survey of its subcellular distribution in the livers of various representatives of the classes mammalia, aves and amphibia. | as part of a wider study on the molecular evolution of alanine:glyoxylate aminotransferase 1 (agt1) intracellular compartmentalization, we have determined the subcellular distribution of immunoreactive agt1, using postembedding protein a-gold immunoelectron microscopy, in the livers of various members of the classes mammalia, aves, and amphibia. as far as organellar distribution is concerned, three categories could be distinguished. in members of the first category (type i), all, or nearly all, ... | 1994 | 7813517 |
| absence of emetic effects of morphine and loperamide in suncus murinus. | the house musk shrew suncus murinus recently has been introduced for the study of emesis. we investigated the emetic effects of the opioids morphine (0.1-21.5 mg/kg i.p.) and loperamide (0.01-10 mg/kg i.p.) and found a complete lack of emetogenic potential. nicotine, however, dose dependently induced vomiting in the suncus with an ed50 of 8.8 mg/kg s.c. and a 100% incidence at 20 mg/kg. this drug-induced vomiting was reduced by morphine or loperamide: ed50 values obtained were 1.2 mg/kg i.p. for ... | 1994 | 8045273 |
| electrophysiological properties of suncus (suncus murinus) cardiac muscle. | 1. electrophysiological properties of cardiac muscle in suncus murinus were compared with those of rat and guinea pig. 2. the resting potential and resting potassium permeability were smallest in suncus heart. 3. the action potential duration in suncus was also shortest, and effects of tetraethylammonium suggested that transient outward current is well developed in suncus. 4. elicitation of slow response was very difficult in suncus, suggesting poor development of the calcium channel. | 1993 | 8102963 |
| activities of drug-metabolizing enzymes in the liver of suncus murinus: possible lack of n-acetyltransferase activity in liver cytosol. | the amounts of several drug-metabolizing enzymes in livers of suncus murinus (suncus) were studied in comparison with rats. the content of cytochrome p450 in suncus was less than one third that seen in rats. activities of glutathione s-transferase, udp-glucuronyltransferase and arylhydroxycarbon hydroxylase in suncus were less than half those in rats. activity of flavin-containing monooxygenase in suncus was 71% that of rats. interestingly, n-acetyltransferase (nat) activity in suncus liver cyto ... | 1994 | 8153148 |
| identification of hairs of three asian commensal mammals: suncus murinus, bandicota bengalensis, and rattus exulans. | hairs of 3 major asian commensal mammals, suncus murinus (l.), bandicota bengalensis (gray and hardwicke), and rattus exulans (peale), were studied, identified, and compared with those of better-known commensal species to provide an overview of their hair morphologies. techniques were developed for authentic hair specimen collection and rapid slide mounting to aid in the timely analysis of food products. the study showed that hairs of b. bengalensis and r. exulans are easily identified to the re ... | 1994 | 8199475 |
| oxygenation of unsaturated fatty acids by hepatic microsomes of musk shrew (suncus murinus). | the cytochrome p-450-dependent monooxygenase in musk shrew (suncus; suncus murinus) liver microsomes metabolized unsaturated fatty acids (oleic, linoleic, alpha-linolenic and arachidonic acids) to a variety of oxygenated products. alpha-linolenic acid was the most active substrate. the oxygenation activity increased with an increase in the number of cis double-bonds in the c18 fatty acids. this suggests that the introduction of cis double-bonds in c18 fatty acids is important for the binding of ... | 1994 | 8205390 |
| presence and differential distribution of distinct forms of immunoreactive gonadotropin-releasing hormone in the musk shrew brain. | gonadotropin-releasing hormone (gnrh) immunoreactive cells and fibers were revealed in olfactory regions, the ventral forebrain, and in the midbrain of the musk shrew (suncus murinus). immunoreactive neurons in olfactory and telencephalic areas were specific for the mammalian form of gnrh. cell bodies in the midbrain, however, cross-reacted with an antibody specific for chicken-ii gnrh. high-performance liquid chromatography and radioimmunoassay analyses confirmed these results; high levels of c ... | 1993 | 8264863 |