| preparation and characterization of an enzymatically active immobilized derivative of myosin. | purified skeletal muscle myosin (ec 3.6.1.3) has been covalently bound to sepharose 4b by the cyanogen bromide procedure. the resulting complex, sepharose-myosin, possesses adenosine triphosphatase activity and is relatively stable for long periods of time. under optimal binding conditions, approximately 33% of the specific atpase activity of the bound myosin is retained. polyacrylamide gel electrophoresis of polypeptides released from denatured sepharose-myosin indicates that 85% of the myosin ... | 1975 | 72 |
| influence of beta-blocking agents on experimental atherosclerosis of cocks (author's transl). | | 1975 | 146 |
| mercury inhibition of avian fatty acid synthetase complex. | (1) subcutaneous or intra-abdominal injections of 8 mg of hgcl2/100 g body weight markedly depressed hepatic fatty acid synthetase activity of chicks at 1 h post-injection. the depression occurred despite the fact that the chicks continued to eat up until the time they were killed. under these same conditions, the hepatic activity of acetyl-coa carboxylase (ec 6.4.1.2) was not affected by hgcl2, while the activity of the mitochondrial system of fatty acid elongation was stimulated. (2) when 2-me ... | 1975 | 150 |
| a comparison of intestinal amino acid absorption in various avian and mammalian species. | | 1976 | 178 |
| the relative importance of monoamine oxidase and catechol-o-methyl transferase on the physiologic response to administered norepinephrine in the turkey. | | 1975 | 200 |
| characteristics of the noradrenergic innervation of the left atrium in the chick (gallus gallus domesticus, l.). | | 1975 | 202 |
| analysis of immunosuppression generated by the graft-versus-host reaction. i. a suppressor t-cell component studied in vivo. | the kinetics and cellular characteristics of immunosuppression in (cba-p x c57/bl)f1 mice during graft-versus-host (gvh) reaction induced with spleen cells from either parental strain have been investigated. effects on pfc responses to thymus-dependent (chicken red blood cells) and independent (levan) antigens have been compared. the unresponsive state which developed in gvh mice was expressed to comparable extent by their spleen cells following transfer to irradiated recipients. furthermore, gv ... | 1975 | 325 |
| tyrosine aminotransferase induction in normal and tumor-bearing chickens. | tyrosine aminotransferase (tat) induction by glucagon and dexamethasone in the liver of tumor-bearing chickens was studied and compared with induction in healthy animals. the transplantable tumor was caused by inoculation of cells from a cell line induced by mc29 avian leukosis virus. tat was hardly detectable in tumor tissue of control and dexamethasone-treated chickens, but it was induced by glucagon to levels which were significant although very low when compared to those in host liver or the ... | 1975 | 337 |
| structural studies of two ovalbumin glycopeptides in relation to the endo-beta-n-acetylglucosaminidase specificity. | heterogeneities of the two ovalbumin glycopeptides, (man)5(glcnac)2asn and (man)6(glcnac)2asn, were revealed by borate paper electrophoresis of oligosaccharide alcohols obtained from the glycopeptides by endo-beta-n-acetylglucosaminidase h digestion and nab3h4 reduction. the structures of the major components of the oligosaccharides were determined by the combination of methylation analysis, acetolysis, and alpha-mannosidase digestion. based on the results, the whole structures of the major comp ... | 1975 | 389 |
| decarboxylation of oxalacetate to pyruvate by purified avian liver phosphoenolpyruvate carboxykinase. | phosphoenolpyruvate carboxykinase, which has been isolated from chicken liver mitochondria in essentially homogenous form, carries out the irreversible decarboxylation of oxalacetate to pyruvate in the presence of catalytic amounts of gdp or idp, as well as the reversible decarboxylation of oxalacetate to phosphoenolpyruvate in the presence of substrate amounts of gtp or itp. the pyruvate- and phosphoenolpyruvate-forming reactions are similar in their nucleoside specificity and appear to be carr ... | 1975 | 392 |
| hydrolysis of the hen egg vitelline membrane by cock sperm acrosin and other enzymes. | a technique utilizing pregnant mare's serum gonadotropin and human chorionic gonadotropin treatment of hens (gallus domesticus), followed by manual ovulation of the excised follicles, was developed to obtain a large number of mature ova. the intact ova were used to test whether acrosin, partially purified from the spermatozoa of the cock (gallus domesticus), partially purified rabbit testicular acrosin and commercial preparations of several hydrolytic enzymes could dissolve the inner vitelline m ... | 1975 | 454 |
| some mechanisms of reduction of carotenoid levels in chickens infected with eimeria acervulina or e. tenella. | the levels of plasma carotenoids were markedly reduced in broiler cockerels infected with eimeria acervulina or e. tenella. the mechanisms of this depigmentation differed between the two species, being primarily associated with interference of absorption of xanthophyll (carotenoids) from the intestinal lumen with e. acervulina infection and with leakage through the damaged wall of the cecum with e. tenella infection. chicks reared on an essentially carotenoid-free diet and inoculated with e. ace ... | 1975 | 476 |
| the avian erythrocyte: a study of fixation for electron microscopy. | the quality of ultrastructural preservation of the avian erythrocyte achieved using various fixation techniques is evaluated. different combinations of initial fixatives, buffers and post-fixation procedures were tested as well as variations in fixative osmolarity, ph and temperature. of the commonly used initial fixatives (glutaraldehyde, acrolein and formaldehyde), 2% glutaraldehyde, alone in a slightly hypertonic buffer containing divalent ions, produced optimum erythrocyte preservation. the ... | 1975 | 508 |
| properties of nad-pyrophosphorylase of the nuclei of liver cells of chickens. | certain characteristics of chicken liver cells nuclei nad-pyrophosphorylase (nmn-adenylytranspherase, ec 2.7.7.1) were investigated. it was established that nad-pyrophosphorylase activity optimum ph is within interval of 7.0-7.5; temperature optimum - 38-39 degrees c; factor q10 is equal to 2. enzyme activation energy, inactivation energy and enthalpy were calculated; apparent km values of nad-pyrophosphorylase with respect to nmn and atp are equal to 1.62-10(-7) m and 2.61-10(-7) m, respectivel ... | 1975 | 833 |
| experimental ulcer. | | 1975 | 855 |
| separation of low molecular weight rna by polyacrylamide gel electrophoresis. | | 1975 | 925 |
| the virus hypothesis in systemic lupus erythematosus. | type-c viruses are currently the prime etiologic candidates in systemic lupus erythematosus. on the basis of knowledge gained from studies of experimental and human models of chronic viral disease, there are possible pathogenetic roles of a virus in systemic lupus erythematosus. experimental attempts at implicating specific viruses have been predominantly negative, but evidence for enhanced type-c-virus expression has recently been reported. | 1975 | 938 |
| amp-deaminase of human skeletal muscle. divalent metal cations and catalytic activity. | | 1975 | 1005 |
| some physical and chemical properties of serinesulfhydrase from chicken liver. | an improved procedure of purification of serinesulfhydrase from chicken liver is described. preparations of enzyme (700-fold purification with the yield of 40 per cent from total activity) have been obtained homogeneous on polyacrylamide gel electrophoresis. molecular weight of serinesulfhydrase is 90.000; 1 mole of enzyme contains 2 moles of pyridoxalphosphate and consists apparently of 2 subunits. amino acid composition of the enzyme is studied. absorption spectrum of serinesulfhydrase has a m ... | 1975 | 1109 |
| evidence for noradrenaline and adrenaline as sympathetic transmitters in the chicken. | 1 the concentrations of noradrenaline and adrenaline in various organs, arterial plasma and venous outflow from isolated hearts of adult chickens have been determined. 2 the relative adrenaline concentrations (percentage of the sum of noradrenaline and adrenaline) in the heart (33%), spleen (16%) and brain (26%) were higher than those found in mammalian organs. chemical sympathectomy by pretreatment with 6-hydroxydopamine caused a decrease of the noradrenaline and adrenaline concentrations in th ... | 1975 | 1132 |
| ontogeny of immunity in humans. | | 1975 | 1167 |
| changes in plasma glucose and liver glycogen following the administration of gluconeogenic precursors to the starving fowl. | | 1975 | 1190 |
| the interaction of organic phosphates with human and chicken hemoglobin. | in this study of the binding properties of inositol hexaphosphate and 2,3-bisphosphoglycerate to chicken and human deoxyhemoglobin and carboxyhemoglobin were compared. it appeared that in all cases the binding to chicken hemoglobin is much stronger than to human hemoglobin. this is very probably due to the fact that 4 out of the 12 residues, responsible for the binding of phosphates in chicken hemoglobin, are arginines. these are absent in human hemoglobin, where the binding site is made up to o ... | 1975 | 1272 |
| studies on biosynthesis of soluble lens crystallin antigens in the chick by isoelectric focusing in thin-layer polyacrylamide gel. | | 1976 | 1281 |
| hemoglobin function in the vertebrates: an evolutionary model. | comparative data on quaternary structure, cooperativity, bohr effect and regulation by organic phosphates are reviewed for vertebrate hemoglobins. a phylogeny of hemoglobin function in the vertebrates is deduced. it is proposed that from the monomeric hemoglobin of the common ancestor of vertebrates, a deoxy dimer, as seen in the lamprey, could have originated with a single amino acid substitution. the deoxy dimer has a bohr effect, cooperativity and a reduced oxygen affinity compared to the mon ... | 1975 | 1543 |
| metabolic characteristics of cells infected with a herpesvirus of turkeys. | chicken embryo fibroblasts infected with the nononcogenic herpesvirus of turkeys (hvt) displayed an increased rate of glucose uptake, a pronounced alteration of the ph of the medium, and an increased production of lactic acid when compared to mock-infected cultures. objective estimates of cytopathology (quantifiable neutral red uptake and cell protein determination) showed that cell deterioration was a slow process in hvt-infected cells when compared to infection by herpes simplex virus. experim ... | 1975 | 1548 |
| copper-induced activation of aortic lysyl oxidase in vivo. | raising day-old chicks on diets lacking copper severely depressed the activity of lysyl oxidase, a copper metalloenzyme in connective tissue. administration of cuso4 either through the diet or through intraperitoneal injections restored the lysyl oxidase activity in aortic tissue. two hours after the chicks received cuso4 (1 mg/kg) the activity of lysyl oxidase rose rapidly to attain, within 4-6 hr, a new steady-state level which was five to 20 times higher than the basal (saline-injected) activ ... | 1976 | 1753 |
| studies of in vitro cultivated cells from the smooth muscle organs. 3. effectiveness of some drugs on pulsation frequency of isolated smooth muscle cells of the chicken amnion. | the effects of some drugs on the beating frequency of isolated cells of the chick amnion cultivated on cover slips were investigated. cholinergic and adrenergic agonists and antagonists, serotonine, antispasmodics, coronary dilatants and local anesthetics influenced the beating frequency significantly. the isolated chick amnion cells equal in their pharmacological behaviour the intact chick amnion and smooth muscle cells of mammals but differ from isolated beating heart cells. | 1975 | 1953 |
| classification and biological distribution of histamine receptor sub-types. | the distribution and classification of histamine receptors in mammalian and avian tissues have been summarized in tables 1-4. it is evident that histamine receptors are present on a number of morphologically distinct cell types and the proportion of cells bearing h1- and h2-receptors varies not only with the species but also with the cell source. the pharmacological receptors mediating mepyramine-sensitive histamine responses have been defined as h1-receptors. receptors mediating mepyramine-resi ... | 1975 | 1979 |
| effect of ph on the growth and cytopathogenicity of avian infectious bronchitis virus in chick kidney cells. | the growth of avian infectious bronchitis virus (ibv) in chick kidney cells at different ph values in the range 6.0-9.0 demonstrated that although the virus was released at a much faster rate at the higher ph values the titre tended to drop more quickly. at the acid ph values the virus was released more slowly but reached a maximum titre similar to that at the higher ph values and showed only minimum reduction in infectivity up to 49 hours post inoculation. the stability of virus in tissue cultu ... | 1975 | 2145 |
| effect of dietetic and hormonal factors on ornithine transaminase and tyrosine transaminase of the chichen liver. | | 1975 | 2269 |
| chromatin-bound protease: degradation of chromosomal proteins under chromatin dissociation conditions. | a chromatin-bound protease, active in 2 m nacl-5 m urea or 5 m urea alone, was demonstrated in rat liver, kidney, testes, brain, rabbit bone marrow, chicken reticulocyte, and ehrlich ascites chromatin. chicken erythrocyte chromatin did not possess any detectable proteolytic activity in salt and urea. the proteolytic activity of rat liver chromatin in salt and urea was found to be independent of the methods of chromatin preparation. the protease can be inhibited by the serine specific reagents ph ... | 1976 | 2280 |
| developmental variations of tyrosine hydroxylase and acetylcholinesterase in embryonic and post-hatching chicken sympathetic ganglia. | the developmental variations of tyrosine hydroxylase (th) and of acetylcholinesterase (ache) were studied in embryonic and post-hatching chicken sympathetic ganglia. different levels of th activity were found in two different flocks of white leghorn chicken, which are probably dependent on genetic differences. these enzymatic differences, however, do not become apparent before hatching and may indicate a combined effect of genetic variation and functional demands. during the period of incubation ... | 1976 | 2367 |
| studies on avian erythrocyte metabolism--ii. relationship between the major phosphorylated metabolic intermediates and oxygen affinity of whole blood in chick embryos and chicks. | | 1976 | 2411 |
| mediation of glucagon in the response of the domestic fowl to stress. | | 1976 | 2415 |
| a procedure for location and removal of the lachrymal and harderian glands of avian species. | | 1976 | 2419 |
| analysis of the structural forms of alpha-amylase present in chicken (gallus domesticus) pancreatic duct juice and intestinal lumen. | | 1976 | 2446 |
| separation of pesticide residues from lipids prior to gas-liquid chromatographic analysis. | lipids are separated from dieldrin, endrin, and p,p'-dde residues by saponification in ethanolic sodium hydroxide, acidification with dilute sulfuric acid, and adsorption chromatography on deactivated alumina, using petroleum ether as the eluant. dieldrin, endrin, and p,p'-dde are efficiently recovered (95-102%), and p,p'-ddt is converted to p,p'-dde, which is then recovered with high yield (90-96%). extremely low lipid carryover (less than 0.3-0.5%) is observed for 0.5-1.0 g samples of chicken ... | 1976 | 2580 |
| effects on tryptophyl absorption of the ionization of the catalytic carboxyls in hen and turkey lysozymes. | the difference spectra of hen and turkey egg-white lysozymes ec 3.2.1.17 produced by acidification were measured. the difference spectra of both lysozymes had peaks at 295 and 301 nm which are characteristic of tryptophyl residues. the ph dependence curves of the extinction differences (delta eplision) at 301 nm and 295 nm for hen lysozyme were identical with the corresponding curves for turkey lysozyme. the ph dependence of delta eplision at 301 nm was analyzed assuming that the extinction at 3 ... | 1975 | 2583 |
| demonstration of a precursor-product relationship between soluble and cross-linked elastin, and the biosynthesis of the desmosines in vitro. | direct evidence showing that a soluble form of elastin is the precursor of cross-linked elastin was obtained from pulse-chase experiments using chick embryo aortas and by demonstrating the conversion of soluble elastin into cross-linked elastin in a cell-free system. acetic acid extracts of embryonic chick aorta pulse-labeled with 14clysine contain two radioactive proteins of molecular weights 74,000 and 138,000 which have been identified previously as soluble elastin and the pro-alpha chain of ... | 1976 | 2602 |
| lymphoid cell fractionation by aggregated immunoglobulin-agarose columns. | fractionation by columns of aggregated rat immunoglobulin (agg ig)-agarose was investigated as a method of separating different populations of lymphoid cells. with rat spleen cells, agg ig columns retained phagocytes, igm- and igg-antibody-forming-cells, cells mediating antibody- or pha-induced lysis of chicken erythrocytes, and specifically immune splenocytes lytic to chicken erythrocytes without exogenous antibody. agg ig columns did not selectively remove 'b lymphocytes' (surface-ig-bearing l ... | 1976 | 2637 |
| the effect of dietary vanadium on fatty acid and cholesterol synthesis and turnover in the chick. | day-old male, broiler type chicks were used to study the effect of 100 ppm dietary vanadium on fatty acid and cholesterol synthesis and turnover in vivo. after feeding the experimental diets for 4 weeks body weight and liver weight of chicks fed 100 ppm vanadium were significantly less than those of the control chicks and liver total lipid and cholesterol tended to be slightly higher than the levels of the control chicks. 1-14c acetate was administered intravenously and the specific activities o ... | 1976 | 2654 |
| cysteine sulfinate carboxylase in the visual pathway of adult chicken. | | 1976 | 2830 |
| uric acid as electronic acceptor of chicken liver's xdh (author's transl). | uric acid seems to act as an electronic acceptor in the dehydrogenation of hypoxanthine catalyzed by chicken liver's xanthinedehydrogenase (xdh). oxidation was observed in crude homogenates under anaerobic conditions, although dialyzed homogenates or purified hepatic xdh also induce a similar action either in aerobic or anaerobic conditions. the reaction ph optimum is about 6.0. xanthine appears to be the only inhibited product of the reaction when its concentration is greater than 1 x 10(-4) m. ... | 1975 | 2955 |
| bacteriological and physicochemical studies of the meat from poultry with acute marek's disease. | studied were bacteriologically a total of 114 birds affected with acute marek's disease (40 broilers, 44 growing layers, and 30 adult layers) as well as 100 healthy control birds of the same three categories. a chemical analysis was performed of the red and white meat of 20 of the diseased pullets and 20 of the diseased adult layers as well as of 34 of the affected broilers. the investigation included the same numbers of the control birds. extractions of the sampled meat were studied in terms of ... | 1975 | 3015 |
| the effect of acid proteinase inhibitors on chicken pepsin. | 1. the activity of chicken pepsin was partially inhibited by dimethyl-(2-hydroxy-5-nitrobenzyl)sulphonium bromide, but was unaffected by p-bromophenacyl bromide. 2. in the presence of cu2+, diazoacetylnorleucine methyl ester completely inactivated chicken pepsin with the incorporation of 1 mol/mol. the mechanism of the reaction was similar to that with pig pepsin. 3. chicken pepsin was completely inactivated by 2-diazo-4-bromoacetophenone in the presence of cu2+. 4. chicken pepsin was almost com ... | 1975 | 3165 |
| iron oxidation and transferrin formation by phosvitin. | the catalytic activity of phosvitin in fe(ii) oxidation and the addition of iron to transferrin were studied under various conditions. it was concluded that the fe(ii) oxidized by phosvitin would bind to apotransferrin, although an appreciable fraction of fe(iii) remained bound to phosvitin. fe(iii) also migrated from phosvitin to apotransferrin. this reaction was first-order with respect to fe(iii)-phosvitin concentration with a half-time (t1/2) of 10 min, and a first-order rate constant, k=0.0 ... | 1975 | 3172 |
| effect of bombesin on pancreatic and gastric secretions under different conditions of acidification of the proventriculus in chickens. | | 1975 | 3189 |
| electrofocusing and kinetic studies of adult and embryonic chicken pyruvate kinases. | chicken embryos less than 15 days old contain only the k isozyme of pyruvate kinase, which appears to exist in vivo as an r,t conformational set with pi values of 7.2 and 6.6, respectively. sets of lower pi and higher pi k-isozyme variants also are obtained. whole embryos of 15 days or more of development show progressively increasing amounts of higher pi, lower k0.5s enzymatic variants. tissue distribution and kinetic properties suggest that the highest pi form (ph 8.8-9.0) is an m-isozyme anal ... | 1976 | 3208 |
| measurement of 25-hydroxyvitamin d3 in serum. | we describe a method for measuring 25-hydroxyvitamin d3 in serum. extraction with dichloromethane/methanol (2/1 by vol), followed by chromatography on a column of sephadex lh-20, resulted in an overall analytical recovery of 82% +/- 3.5% (sd). diluted normal rat serum was used as binding protein because it contains a transport protein that has both a high affinity (ka = 2 x 10(10) liter/mol) and a high capacity (3 x 10(-6) mol/liter) for 25-hydroxyvitamin d3. there is no advantage in using more ... | 1976 | 3295 |
| the shivering pattern in an arctic (willow ptarmigan) and a tropical bird (bantam hen). | | 1976 | 3318 |
| renal urate synthesis in the fowl (gallus domesticus). | | 1976 | 3325 |
| developmental patterns of intestinal transport mechanisms in the chick. | | 1976 | 3330 |
| stimulatory effects of ammonia and glutamine on uric acid synthesis in the chicken (gallus domesticus) treated with methionine sulfoximine. | | 1976 | 3356 |
| the binding of catecholamines to the serum proteins of the rat and the domestic fowl. | | 1975 | 3370 |
| metabolism of 2-(3-chloro-4(4-chlorobenzoyl)-phenyl)-as-triazine-3,5(2h,4h)-dione by the chicken. | the metabolism of the anticoccidial 2-3-chloro-4-(4-chlorobenzoyl)phenyl-as-triazine-3,-5(2h,4h)-dione (cp-25,415) was investigated in the chicken. it was shown that the predominant residue present in the chicken was 2-3-chloro-4-(alpha-hydroxy-4-chlorobenzoyl)phenyl-as-triazine-3,5(2h,4h)-dione (cp-25,641). a gas-liquid chromatographic assay for the analysis of cp-25,641 in biological fluids and tissues was developed which was rapid, accurate, and reproducible. results of the analytical method ... | 1976 | 3402 |
| studies of the histidine residues of triose phosphate isomerase by proton magnetic resonance and x-ray crystallography. | | 1976 | 3655 |
| morphogenesis and physiogenesis of the retino-tectal connection in the chicken. i. the retinal ganglion cells and their axons. | | 1976 | 3794 |
| morphogenesis and physiogenesis of the retino-tectal connection in the chicken. ii. the retino-tectal synapses. | | 1976 | 3795 |
| effects of dietary vitamin d and calcium on lysyl oxidase activity in chick bone metaphyses. | activity of lysyl oxidase, an enzyme responsible for production of aldehydic precursors for lysine-derived collagen crosslinks, was measured in tibial metaphyses from chicks receiving different dietary levels of vitamin d and ca for 2 weeks after hatching. enzyme activities were increased twofold in d-deficient chicks compared to activities from chicks receiving control levels of vitamin d. addition of ca to the d-deficient diet had no effect on lysyl oxidase activity. it is suggested that vitam ... | 1976 | 3797 |
| characteristics of heterogeneity of serum albumin in heterosis-hybrid chickens. | a comparative study was performed for isoelectric and electrophoretic spectra blood serum albumin of parental breeds of chickens and their heterosis hybrids --broiler cocks. the method of isoelectric focusing within the surcrose density gradient and ph 4-6 created by the gradient of sucrose, mannitol and boron-borate buffer (ph 8.5) concentrations was applied. the electrophoretic spectrum of the serum albumin fraction homogeneous in the agar gel was obtained by electrophoresis in 7% polyacrylami ... | 1976 | 3872 |
| ecologic studies of venezuelan encephalitis virus and isolations of nepuyo and patois viruses during 1968-1973 at a marsh habitat near the epicenter of the 1969 outbreak in guatemala. | ecologic studies of venezuelan encephalitis (ve) virus at a marsh habitat near the epicenter of the 1969 outbreak in guatemala revealed that the virus was enzootic there. ve virus was isolated yearly during 1968-1973 from sentinel hamsters exposed during the rainy seasons and from mosquitoes collected during july and august 1970. hamsters yielded 41 strains of ve virus and virus was detected within 2 km of the edge of the marsh, in its interior, and at its western extreme 18 km from the central ... | 1976 | 3981 |
| induction of microsomal stearyl coenzyme a desaturase in the newly hatched chicks. | | 1976 | 4026 |
| chicken liver fructose 1,6-bisphosphatase:purfication and some properties. | | 1976 | 4029 |
| thermoregulation in the young fowl (gallus domesticus). | | 1976 | 4262 |
| analysis of phosphate metabolites, the intracellular ph, and the state of adenosine triphosphate in intact muscle by phosphorus nuclear magnetic resonance. | 31p nuclear magnetic resonance spectra recorded from intact muophosphate, and the sugar phosphates. quantitation of these metabolites by 31p nuclear magnetic resonance was in good agreement with values obtained by chemical analyses. the spectra obtained from various muscles showed considerable variation in their phosphorus profile. thus, differences could be detected between (a) normal and diseased muscle; (b) vertebrates and invertebrates; (c) different species of the same animal. the time cour ... | 1976 | 4452 |
| electron microscopy of myosin molecules from muscle and non-muscle sources. | | 1976 | 4809 |
| the biological actions of thyrotropin. | | 1975 | 4827 |
| macrocyclic intermediates in the biosynthesis of porphyrins. | the hepta-, hexa- and penta-carboxylic porphyrins found in the faeces of rats poisoned with hexachlorobenzene have been separated by high-pressure liquid chromatography and characterized largely by spectroscopie methods. their structures were confirmed by total synthesis, as part of a programme in which eleven of the fourteen hepta-, hexa- and penta-carboxylic porphyrins derived from uroporphyrin iii have now been synthesized as their methyl esters. the four isomeric heptacarboxylic and three of ... | 1976 | 4837 |
| suppressor cells in the embryonic thymus mediate allograft tolerance. | thymus cells from non-immunized young chickens suppress the allograft rejection in lightly irradiated syngeneic or allogeneic recipients and mediate longlasting skingraft survival in a significant proportion of recipients across a strong histocompatibility difference. suppressive activity of this kind is already found in the embryonic thymus and is therefore believed to mediate also self tolerance and neonatal allograft tolerance. | 1976 | 4964 |
| the influence of fodder mineral substances on the inner quality of eggs. | | 1975 | 5073 |
| cellular basis for increased sensitivity of vascular smooth muscle in spontaneously hypertensive rats. | there is evidence that hypersensitivity of vascular muscle to neurotransmitters contributes to the development of hypertension. comparison of the caudal arteries of spontaneously hypertensive rats (shr) and their genetically related kyoto-wistar normotensive control rats (knr) showed that although there is no difference in membrane potential under unstimulated conditions, greater depolarization of the shr vascular muscle cells by norepinephrine occurs at concentrations which cause greater contra ... | 1976 | 5207 |
| comparative biochemistry of antarctic proteins. | | 1976 | 5216 |
| proteolytic activity in ptarmigan muscle. | | 1976 | 5229 |
| hind gut function in the domestic fowl. | | 1976 | 5244 |
| effects of na+ depletion, theophylline and 2,4-dinitrophenol on neutral amino acid influx and cyclic adenosine 3':5'-monophosphate levels in chicken small intestine. | | 1976 | 5246 |
| ph dependence of the binding constants of n-acetylglucosamine monomers to hen and turkey egg-white lysozymes. | the binding constants of n-acetylglucosamine (g1cnac) and its methyl alpha- and beta- glycosides to hen and turkey egg-white lysozymes ec 3.2.1.17, in the latter of which asp 101 is replaced by gly, were determined at various ph values by measuring changes in the circular dichroic (dc) band at 295 nm. the binding of beta-methyl-g1cnac to turkey and hen lysozymes perturbed the pk value of glu 35 from 6.0 to 6.5, the pk value of asp 52 from 3.5 to 3.9, and the pk value of asp 66 from 1.3 to 0.7. i ... | 1975 | 5413 |
| triglyceride, diglyceride, monoglyceride, and cholesterol ester hydrolases in chicken adipose tissue activated by adenosine 3':5'-monophosphate-dependent protein kinase. chromatographic resolution and immunochemical differentiation from lipoprotein lipase. | hormone-sensitive lipase and cholesterol ester hydrolase of chicken adipose tissue were markedly activated by adenosine 3':5'-monophosphate (camp)-dependent protein kinase (on the average, 235 to 275%; occasionally as much as 1000%). diglyceride and monoglyceride hydrolases were also activated, but to a lesser extent (60 to 87%). the activation of all four hydrolases was inhibited by protein kinase inhibitor and reversed by the addition of exogenous protein kinase. following activation by camp-d ... | 1976 | 5445 |
| glucocorticoid potency and parachor. | | 1976 | 5630 |
| comparative aspects of buffering capacity in muscle. | these findings are discussed in relation to the contention that a high buffer value is linked to a high work performance. this generalization does not extend to the "white" breast muscle of chicken. its high buffer value is in part due to a high content of the dipeptides carnosine and anserine. additionally, a hypothesis is advanced that muscle, e.g. pigeon breast muscle, can in part regulate intracellular ph by changes in the steady state concentrations of the glycolytic and citric acid cycle a ... | 1975 | 5763 |
| comparative study of the optimum ph value of serum alkaline phosphatase in various species of farm animals. | investigations were carried out on the alkaline phosphatase in the sera of cattle, horses, pigs, sheep, goats, and chickens, the ph value of the buffer used being 9.0-9.8-10.0-10.2-10.6 and 11.0, and the method applied--that of richterich. the ph value at which the serum alkaline phosphatase in the various farm animals and birds was most active was found to vary to a large extent. optimal values for the enzyme's activity usually range as follows: cattle, 10.2; pigs and goats, 10.0; sheep,--10.2; ... | 1975 | 5802 |
| characterization of an endotoxic lipopolysaccharide from coxiella burnetii. | phase i coxiella burnetii antigen isolated by phenol extraction from purified suspensions of c. burnetii in phase i is a complex lipopolysaccharide (lps) molecule containing substances typical of the bacterial lps. some endotoxic properties of this c. burnetii lps, namely pyrogenicity and skin epinephrine reaction in rabbits, hypothermia in white rats, lethal effect on chicken embryos or on actinomycin-d-treated mice are similar to those of lps isolated from other gram-negative bacteria. | 1976 | 5871 |
| formation of interferon with chicken species-specificity in bacterial cells. | | 1976 | 5875 |
| soluble, nuclear and mitochondrial forms of dehydrogenases, pentose-phosphate pathway transferases and nucleases in chicken liver. | the sub-cellular topography of oxidative and non-oxidative enzymes of the pentose phosphate pathway of carbohydrates metabolism and enzymes of the nucleic exchange (acid and alkaline deoxyribonucleases and ribonucleases) in chicken liver is studied. nuclear and mitochondrial forms of the enzymes are discovered. the activity of the enzymes studied of carbohydrates metabolism is shown to correlate with that of the enzymes of nucleic metabolism in cytosol, nucleic and mitochondrial liver fractions. | 1976 | 6078 |
| biochemical characterization of an avian spermatozoan acrosin and comparison of its properties to those of bovine trypsin and mammalian acrosins. | | 1976 | 6190 |
| effect of propylthiouracil feeding on plasma na+ and k+ levels in the chick (gallus domesticus). | | 1976 | 6206 |
| oxygen dissociation curve for chorioallantoic capillary blood of chicken embryo. | oxygen dissociation curves for blood in the chorioallantoic capillary of chicken embryos were determined using a microphotometric apparatus made for measuring the reaction velocity of a red blood cell with oxygen and carbon monoxide. the modified hill's equations expressing the dissociation curve during development were calculated by two methods. p50's at ph of 7.4 were found to be 60.0, 54.4, 46.2, 33.1, and 28.6 mmhg for 10, 12, 14, 16 and 18 days of incubation, respectively. although the bohr ... | 1976 | 6417 |
| binding of n-acetyl-chitotriose to human lysozyme. | the interaction of n-acetyl-chitotriose ((glcnac)3) with human lysozyme ec 3.2.1.17 was studied at various ph values by measuring changes in the circular dichroic (cd) band at 294 or 255 nm and the data were compared with the results for hen and turkey lysozymes reported previously (kuramitsu et al. (1974) j. biochem.76, 671-683; kuramitsu et al. (1975) j. biochem. 77, 291-301). the ph dependence of the binding constant of (glcnac)3 to human lysozyme was different from those for hen and turkey l ... | 1975 | 6438 |
| a transition state analog of lysozyme catalysis prepared from the bacterial cell wall tetrasaccharide. | treatment of the cell wall tetrasaccharide glcnacbeta(1 leads to 4)-murnac-beta(1 leads to 4)-glcnac-beta(1 leads to 4)-murnac with alkali resulted in the formation of the unsaturated tetrasaccharide glcnac-beta(1 leads to 4)-murnac-beta(1 leads to 4)-glcnac-beta(1 leads to 4)-delta2,3-2-acetamido-2-deoxy-d-glucoseen. the same compound was also formed by transglycosylation upon incubation of the unmodified tetrasaccharide with the unsaturated disaccharide glcnac-beta(1 leads to 4)-delta2,3-2-ace ... | 1976 | 6476 |
| antibody-dependent cell-mediated cytotoxicity in selected autoimmune diseases. | antibody-dependent cell-mediated cytotoxicity mediated by peripheral blood lymphocytes was studied in patients with systemic lupus erythematosus, polyarteritis nodosa. sjogren's syndrome, and rheumatoid arthritis. the target cells were chicken erythrocytes coated with rabbit anti-chicken erythrocyte antibody. antibody-dependent cell-mediated cytotoxic activity was normal in sjogren's syndrome and rheumatoid arthritis but significantly decreased (p is less than 0.001) in active systemic lupus ery ... | 1976 | 6490 |
| acetylcholinesterase and responses to acetylcholine in the embryonic chicken heart. | three and 4 day old embryonic chicken hearts were examined for their responsiveness to acetylcholine and presence of acetylcholinesterase (ache) to determine the role of the enzyme in the cardiac effects of the transmitter. the effects of acetylcholine on rate and contractility of 3 day old hearts were indistinguishable from those on 4 day old hearts. the effects were readily blocked by atropine at both stages of development. in 3 day old hearts the responses to acetylcholine were not affected b ... | 1976 | 6692 |
| the discovery of uptake of adrenaline in 1930-1933 and the development of the adrenergic fibre from a cholinergic fibre. | | 1976 | 6737 |
| characterization of whitney's clethrionomy gapperi virus isolates from massachusetts. | six strains of virus were recovered from the blood and/or liver of five clethrionomys gapperi ochraceus trapped in southeastern massachusetts during 1969. biological, antigenic and physiochemical properties of these isolates are reported. usa m-2268a was selected as the reference strain. this strain was identical by complement-fixation and neutralization tests to whitneys c. gapperie virus (usa 64-7855) from new york state and was related to, but distinct from, an unpublished agent (johnson's mi ... | 1976 | 6801 |
| on the presence of a "particle-bound" neuraminidase in retina: a developmental study. | | 1976 | 6852 |
| changes in plasma electrolytes, acid-base balance and other physiological parameters of adult female turkeys under conditions of acute hyperthermia. | the effects of acute hyperthermia on certain physiological parameters of turkey hens was studied. it was found that the response of the turkey to hyperthermia is similar to the reported response of the chicken. the birds began panting and the average body temperature increased 0.1 degrees c. as the ambient temperature reached 32 degrees c. the panting or polypnea induced a profound respiratory alkalosis in the turkeys. the acute hyperthermia also caused a significant (p less than 0.05) decrease ... | 1975 | 6952 |
| observation of individual carboxyl groups in hen egg-white lysozyme by use of high field 13c-nuclear magnetic resonance. | several of the carboxyl carbon atom resonances of hen egg-white lysozyme (mucopeptide n-acetylmuramoyl hydrolase, ec 3.2.1.17) have been resolved by 13c-nuclear magnetic resonance (nmr) at 68 mhz. the change in chemical shift of the carboxyl carbon atom resonances, as a function of ph, has enabled the distinction of these resonances against the background of many nontitrating carbonyl group resonances. several apparent microscopic ionization constants have been determined from the carboxyl group ... | 1976 | 6962 |
| mechanisms and regulation of biosynthesis of saturated fatty acids. | | 1976 | 6981 |
| synaptic chemistry of identified cells in the vertebrate retina. | | 1976 | 7386 |
| upper respiratory dead space in the chicken: its fraction of the tidal volume. | | 1976 | 7394 |
| metabolism of avian twitch and tonus muscle. | | 1976 | 7395 |