general survey of the present distribution of helminths in iran and comparison with those of past this paper the literature on helminthiasis in iran is reviewed and the distribution, prevalence and intensity of infections caused by helminths are discussed. a comparison of prevalence and intensity of infections was accomplished in the recent 10 years by the author. hookworm infections are found mostly in the north along the caspian sea, but its prevalence is declining. trichostrongylus are found in iran with a high prevalence in central country. schistosoma haematobium is found in one prov ...19768977
the effect of trichinella spiralis on graft-versus-host reaction, transplantation immunity and antibody formation.the effect of trichinella spiralis in different phases of infection on transplantation immunity, the ability of lymphocytes to induce graft-versus-host reaction, on antibody and plaque-forming cell production was studied. in certain phases of trichinella spiralis beginhing from the first days of infection and during 40 days significant suppression of transplantation immunity was observed. thus, on the 24th day of infection skin allograft necrosis occurred much later (26.2 days) as compared with ...197611851
the etiology of sylvatic trichinellosis in switzerland.three trichinella strains from swiss wild foxes (vulpes vulpes) were tested in crossbreeding experiments with trichinella spiralis, t. nativa and t. nelsoni using white mice as laboratory animals. the results demonstrated that t. nelsoni britov et boev 1972 is the etiologic agent of sylvatic trichinellosis in switzerland. former isolations of these species were successful in materials from east and south africa, ussr (republics of tadzhikistan, turkmenia and kazakhstan) and bulgaria. the area of ...197723655
depression of cell-mediated immunity following inoculation of trichinella spiralis extract in the mouse.mice pretreated with trichinella spiralis extract (tse), or infected with the parasite, rejected primary skin allografts in 18-23 days and secondary allografts in 12-16 days. mice pretreated with saline or with bovine serum albumin (bsa) rejected the primary allografts in 12-18 days and did not accept the secondary grafts. inoculation of increasing doses of parental spleen cells from mice pretreated with saline or with bsa in f1 hybrids produced proportionately stronger graft-versus-host reactio ...197823994
mechanisms of killing of newborn larvae of trichinella spiralis by neutrophils and eosinophils. killing by generators of hydrogen peroxide in vitro.eosinophil and/or neutrophil leukocytes appear to have important roles in host defense against invasive, migratory helminth infestations, but the mechanisms of larval killing by leukocytes are uncertain. this study examines killing of newborn (migratory phase) larvae of trichinella spiralis during incubation with granule preparations of human eosinophils or neutrophils and generators of hydrogen peroxide (glucose-glucose oxidase) (g-go) or superoxide and hydrogen peroxide (xanthine-xanthine oxid ...197941002
report concerning trichinella spiralis studies in the netherlands 1977-1978. 1. epidemiological and epizootiological situation in the netherlands. 197944396
effect of infection with trichinella spiralis and bcg on thymic histology.the histology of mouse thymic tissue was examined following infection with trichinella spiralis and/or bcg. icr/cd-1 mice were orally infected with 200 t. spiralis 56 days preceding intravenous administration of 4x10-6 viable bcg. following assessment of delayed hypersensitive foot pad reactions to bcg, the mice were bled and sacrificed. the thymus was removed from each animal, fixed in 10% neutral buffered formalin, embedded in paraffin and cut in 4 mum sections. examination of serial sections ...197549304
trichinella infestation in mice genetically selected for high and low antibody production.mice genetically selected according to their capacity to produce antibodies (high and low responder lines) were infested with trichinella spiralis. high responder mice produced much higher levels of ige and gamma1 serum antibodies than low responder mice. igg and igm antibodies were detected by immunodiffusion analysis or passive haemagglutination only in animals of the high responder line and in very low concentrations. the number of living larvae present in the muscles was very similar in the ...197551004
i. effect of trichinella spiralis infection on the migration of mesenteric lymphoblasts and mesenteric t lymphoblasts in syngeneic mice.the migration of [125i]udr-labelled mesenteric lymph node cells in nih strain mice at various times after inis produced an enhanced accumulation of mesenteric immunoblasts in the small intestine at 2 and 4 days after infection but not at later times. the enhanced migration occurred when using cells from both uninfected and infected donors, denoting an absence of antigenic specificity. this effect is not secondary to a reduced arrival of cells at sites away from the gut in infected mice, but to a ...197662712
[fractionation of the trichinella spiralis antigen and allergy diagnosis trails].experiments were carried out to fractionate an antigen of trichinella spiralis with sephadex g-50 and g-100. the specificty of the fractions has been followed up by means of the intradermal allergic reaction in six pigs, experimentally infected with trichenalla spiralis, one with trichocephalus suis and three, born by trichinellosis-affected sows. the second fraction has been tested also on four pigs, experimentally inoculated with ascaris suum, nine--with ascarsis suum and oesophagostomum and 1 ...197888790
role for activated macrophages in resistance against trichinella determine whether activated macrophages are important in resistance against the intestinal phase of nematode parasites, we studied trichinella spiralis infections in mice with normal macrophages and in mice with macrophages activated by either chronic toxoplasma gondii or acute listeria monocytogenes infections. the peak t. spiralis adult worm burden in the intestines of normal c57bl/6 or swiss webster mice occurred from 6 to 14 days after infection. subsequent expulsion of worms from the int ...197899366
physiological characterization of a biphasic immune response to trichinella spiralis in the rat.secondary infection with trichinella spiralis in the rat was associated with a host response that prevented approximately 80% of the total number of larvae recovered after primary infection from embedding in the intestine. the host response occurred within 15 min after contract of the parasite with intestinal mucosa and was not associated with acute inflammatory cell infiltrates or with the pathophysiology of the primary infection. eventual rejection of the residual population of embedded worms ...1979109546
[observations on a trichinellosis focus].following the consumption of porc infested with trichinella spiralis, there were 21 cases of trichinellosis, of which 15 clinical forms and 6 subclinical cases. the clinical picture was polymorphous, characteristic. in one case of an expectant mother, the pregnancy evolved up to term and the child was born normally. histologic examination of the maternal placenta revealed the presence oe encapsulated parasites. eosinophilia, increasing up to 50%, was found in all the cases, as well as a slight i ...1976134448
[immune elimination of trichinella spiralis in rats. interference with the cellular immunity system]. 1977138323
trichinella spiralis: correlates in vitro of altered immune responsiveness in mice. 1979156123
immunological sequelae of trichinella spiralis infection in mice: effect on the antibody responses to sheep erythrocytes and japanse b encephalitis virus.immunosuppression of the antibody response to japanese b encephalitis (jbe) virus and sheep erythrocytes (srbc) was observed in mice infected with trichinella spiralis. this suppression was paralleled by the presence of fewer antibody-forming cells to srbc in the spleens of parasitized mice. both primary and secondary complement-fixing antibody responses to jbe virus were suppressed, but the development of immunological memory was not affected. parasitized mice demonstrated a normal blastogenic ...1975166916
lethality of disrupted intestinal lamina propia cells for trichinella spiralis in vitro.the possible direct role of inflammatory cells in resistance to trichinella spiralis was studied by observing the effects of lamina propria cells from the small intestine (lp cells) of immunized rats on various stages of the parasite. effects produced by physically disrupted cells were compared to those produced by intact cells on worms exposed to phytohemagglutinin or immune serum. lp cells were isolated from the rat intestine by collagenase digestion of everted gut segments that were previousl ...1975172621
effect of experimentally induced trichinellosis on the infection with erysipelothrix rhusiopathiae in rats.infection with erysipelothrix rhusiopathiae in rats infested 20 days earlier with trichinella spiralis developed more slowly, the clinical and pathoanatomic changes in the joints were expressed to a less extend, and the mortality rate was lower. the erythrocyte sedimentation rate, the precipitin formation and the phagocytic activity of the macrophages did not considerably change. experiments carried out to elucidate this fact did not reveal any antigenic or antagonistic relationships between par ...1978207030
[ultrastructural localization of cytoplasmic phosphatases at different developmental stages of trichinella spiralis (nematoda). i. cytoplasmic phosphatases in hypodermal gland cells (bacillary band cells) of trichinalla spiralis]. 1978208312
foodborne hazards of microbial origin.foods can serve as vehicles of many pathogenic and toxigenic agents of disease. bacterial agents comprise three groups: 1) those that grow in the food and produce an active toxin before consumption (e.g., clostridium botulinium); 2) those that merely exist as contaminants in the food but are able to initiate infection when swallowed (e.g., salmonella spp.); and 3) those that multiply and produce large numbers of vegetative cells in the food, then release an active enterotoxin when they sporulate ...1978212326
trichinella spiralis: acceleration and inhibition of cyst calcification in rats.daily administration of vitamin d3 (75,000 iu/kg b. wt) for 7 days accelerated trichinella spiralis cyst calcification in rats with a 14-week-old infection. when disodium ethane-1-hydroxy-1, 1-diphosphonate (ehdp) was administered (50 mg/kg b. wt) from 2 days before until 2 days after vitamin d3 treatment, cyst calcification was inhibited. thus, the ability to inhibit e. spiralis calcification has demonstrated for the first time.1978215446
electron transport in mitochondria of trichinella spiralis larvae. 1978218888
[ultrastructural localization of cytoplasmic phosphatases in different developmental stages of trichinella spiralis. 2. morphological and cytochemical studies of trichinella spiralis stichosome]. 1979225890
lymphocyte activation induced by trichinella spiralis infection reflected as spontaneous dna synthesis in vitro.spleen cells from mice, infected with trichinella spiralis, were cultured in micro and macrocultures without stimulatory agents. as controls, various polyclonal t and b cell activators were used. during the course of the infection the cells exhibited an increased spontaneous dna synthesis compared to the cells from uninfected controls. it was also found that the relative proportion of theta and ig-positive cells and macrophages was not significantly affected by the infection. to characterize the ...1979230926
eosinophils and resistance to trichinella spiralis.mice infected with trichinella spiralis were depleted of eosinophils by repeated administration of rabbit anti-mouse eosinophil serum. there was no effect on the spontaneous expulsion of adult worms from the small intestines, but the numbers of larvae in the muscles were almost doubled. it is concluded that eosinophils contribute to resistance to the systemic phase of trichinosis.1977233913
trichinella spiralis in new zealand. 1978279880
[reactivity of pig serum against an antigen of trichinella spiralis in 2 serologic tests]. 1978292104
immunity to trichinella spiralis. i. transfer of resistance by two classes of lymphocytes.rats can be solidly immunized against trichinella spiralis by a series of methyridine-terminated oral infections with t. spiralis larvae. injections of thoracic duct lymphocytes (tdl) obtained from such animals can protect normal rats against a trichinella challenge. the protective cells belong to two populations which differ with respect to their adherence to affinity columns prepared with rabbit antibody to rat f(ab')2. immune lymphocytes in the column-adherent b cell fraction are inhibited by ...1977304035
the immunological consequences of nematode infection.nematode infections in the gut induce a strong immune response which is rapidly detected parenterally. the response is thymus-dependent and long-lasting and involves both antibodies and cell-mediated reactions. the immunological response to unrelated antigens, tumours and other infectious organisms is altered in animals infected with nematodes. both antibodies and sensitized lymphocytes participate in the immune response which affects the nematodes themselves, and characteristically the lymphocy ...1977305838
trichinella spiralis: changes caused in the mouse's thymic, splenic, and lymph node cell populations. 1978307495
the accumulation of immunoblasts in extravascular tissues including mammary gland, peritoneal cavity, gut and skin.the migration of [125i]udr labelled mesenteric (mln) and peripheral t immunoblasts (pln) has been followed in mice with multiple sites attractive to immunoblasts. the sites studied were the inflamed gut (produced by trichinella spiralis infection), inflamed skin, the peritoneal cavity and the mammary glands of lactating mice. pln were capable of assembling in all of the four sites and in the presence of both inflamed gut and inflamed skin, pln accumulated preferentially in the skin. mln, in cont ...1978312255
b and t lymphocytes from peripheral blood in mice infected with trichinella spiralis and trichinella pseudospiralis. 1978313234
t and b cells in the transfer of immunity against trichinella spiralis in mice.enriched populations of t or b cells, prepared by nylon wool filtration of mesenteric node lymphocytes from mice infected with trichinella spiralis, were capable of transferring immunity to normal and irradiated syngeneic mice. in cell recipients there was an early loss of fecundity by the worms and an accelerated expulsion from the intestine. treatment with anti-thy 1.2 serum, to deplete contaminating t cells, severely reduced or abolished the protective activity of enriched b-cell fractions. r ...1979313897
response of intestinal globule leucocytes in the mouse during a trichinella spiralis infection and its independence of intestinal mast cells.we have previously reported that intestinal mast cells represent a separate population of mast cells which is thymus- (t-) dependent. in this paper we examine whether the appearance of these cells is dependent on thymus-dependent antibodies or thymus serum factor(s). the response of intestinal mast cells and globule leucocytes to a trichinella spiralis infection was therefore studied in congenitally athymic (nude) mice after treatment with specific anti-t. spiralis hyperimmune serum or normal mo ...1979314302
villous atrophy and expulsion of intestinal trichinella spiralis are mediated by t cells. 1979314854
migration of lymphoblasts to the small intestine. iii. strain differences and relationship to distribution and duration of trichinella spiralis nih strain mice, in which the majority of trichinella spiralis are located in the anterior half of the small intestine early in the enteral phase of infection, enhanced localization of mesenteric lymphoblasts, nylon wool separated mesenteric t-lymphoblasts and even oxazolone sensitized peripheral lymphoblasts is most prominent in the anterior region of the small intestine. as the worms move to the posterior half of the small intestine, enahnced localization of lymphoblasts is observed in that ...1979317031
trichiniasis among the animals in north eastern iran (1), 1969, 1976, 1969, 1976 and 1977, 1,039 rodents and carnivores collected from north east iran were examined for trichinella spiralis. eighty four per cent of golden jackals, 30 per cent of red foxes and nine per dent of dogs were found to be infected. the importance of wild boar sus scrofa as the source of infection is discussed.1979318000
anthelmintics.this article describes the drugs used in helminthic infections and their therapeutic indications, mode of action, toxicity and other details of each of the recommended drugs, and discusses the nature and treatment of infection by helminths important in human medicine. infestation due to the roundworms enterobius vermicularis, ascaris lumbricoides and the hookworms, ancylostoma duodenale and necator americanus can all be treated effectively with pyrantel pamoate. for enterobius vermicularis, howe ...1977319991
effect of experimental trichinosis on unrelated humoral and cell mediated immunity.immune responses to unrelated antigens were studied during the course of trichinella spiralis infection in mice. a transitory depression of the igm response to the thymus dependent antigen, sheep erythrocytes, was seen three weeks after infection and this effect was more pronounced after challenge. a depression of the igg response also was observed, however, not until 6 weeks after infection. the humoral response to the thymus independent antigen, polyvinyl pyrrolidone showed a slight increase w ...1977324236
metabolite levels and activities of some enzymes of carbohydrate metabolism in livers and intestines of conventional and bi-associated (with staphylococcus epidermidis and escherichia coli) mice in the course of trichinella spiralis infection. 1977324584
[mechanizing the enzyme-linked immunosorbent assay (elisa) in repressive testing for trichinella spiralis infections in fattening pigs (author's transl)].the constuction of and procedure adopted in a rail system for use in a macro-enzyme-linked immunosorbent assay (elisa) are described. this method is used in the serodiagnosis of trichinella spiralis infections in fattening pigs. two persons will be able to test 4,000 sera daily using this system.1977331555
autopsy of an egyptian mummy (nakht--rom i).autopsy of a 3200-year-old egyptian mummy by an international multidisciplinary team yielded much information about diseases of the ancient past. major contributions were made by the disciplines of anatomy, dentistry, genetics, hematology, histology, microbiology, nuclear medicine, occupational medicine, orthopedic surgery, otolaryngology, pathology, pediatrics, plastic surgery, radiology and virology. scientists from toronto, detroit, philadelphia and cardiff participated in the investigation. ...1977332299
circulating immune complexes in six patients with trichinosis.the sera of six patients infected with trichinella spiralis were studied for the presence of circulating immune complexes (cic). cic were present in all six patients studied 1 month after infection. in two patients in whom serial serum samples were available, as clinical improvement occurred there was a decrease in the level of cic and an increase in the fluorescent antibody titres.1977342150
effect of trichinella spiralis infection on delayed hypersensitivity to heterologous antigens.studies were initiated to determine the effects of the different phases of the nematode life cycle on the delayed-type hypersensitivity (dth) capabilities of the host. mice were injected intraperitoneally with 4 x 10(6) viable or heat-killed bcg at 0, 3, 7, 14 and 28 days after oral infection with 200 trichinella spiralis larvae. groups were tested for dth 28 days after bcg inoculation by the footpad swelling assay. infection with t. spiralis was found to suppress the response in mice administer ...1978346495
trichinella spiralis: effects on the host-parasite relationship in mice of bcg (attenuated mycobacterium bovis). 1978350600
[specificity of drop passive hemagglutination and indirect immunofluorescence towards trichinella spiralis antigens]. 1978358304
in vitro killing of schistosomula of schistosoma mansoni by bcg and c. parvum-activated macrophages.resistance to schistosoma mansoni infection in the mouse has been induced either specifically by a primary infection with this parasite or nonspecifically by a variety of immunostimulants such as bcg. in the present study we developed an in vitro system to examine the effector mechanism of nonspecifically induced resistance. activated macrophage monolayers obtained from bcg- or corynebacterium parvum treated mice killed a respective mean 32 +/- 6% and 48 +/- 5% of schistosomula after 24 hr incub ...1979376723
[diagnosis of trichinellosis and special aspects of a modified immunofluorescence test (author's transl)].trichinella spiralis was detected in 1835 by paget, an english student. since the introduction of the meat investigation law for trichinosis in 1937 the infection with this parasites became a rare condition. the last endemies in germany occurred in 1967 and 1977. they restimulated the discussion regarding the efficiency and sensitivity of the routinely used methods for the detection of tr. spiralis. 69 patients, suffering from infection with tr. spiralis were investigated using a modified ift. t ...1979396230
report on trichinella spiralis in federal republic of germany 1977-1978. 1. serological examination in humans for trichinellosis. 1979396721
history of trichinosis: paget, owends and the discovery of trichinella spiralis. 1979397841
[antibody-dependent adherence of peritoneal cells of the rat to trichinella spiralis larvae].washed peritoneal exudate cells from normal rats firmly adhere to trichinella spiralis larvae in the presence of serum containing anti-trichinella antibodies. this effect is observed when muscle larvae, cells and dilutions of anti-sera are incubated for 1 hr. at 37 degrees c. no adherence takes place at 4 degrees c. whole serum or its gammaglobulin fraction are active and effect is inhibited by the addition of trichinella antigens. complement is not essential since antiserum heated for 2 hrs. at ...1977404082
[behavior of the serum titer after treatment with mebendazole in guinea-pigs infected with trichinella spiralis (author's transl)].the behavior of the ift serum titer in 80 guinea-pigs, experimentally infected with trichinella spiralis, was tested before and after treatment with mebendazole for 6 months. for 14 consecutive days each animal was drenched with 40 mg mebendazole/kg bw on the 25th, 35th and 45th day after infection. after the 2 weeks therapy, living trichinella larvae were not found in any of the 3 treated groups of guinea-pigs. on the other hand even after 6 months viable larvae were found in the muscular tissu ...1977408642
application of the indirect enzyme-labeled antibody microtest to the detection and surveillance of animal diseases.the rapid, indirect enzyme-labeled antibody (ela) microplate test has been developed as a diagnostic and surveillance tool to aid in the control of animal disease. the test has been applied to viral (hog cholera), parasitic (trichinosis), and bacterial (brucellosis) diseases of animals. a correlation of greater than 95% was observed between the hog cholera ela test and the serum neutralization test for hog cholera in greater than 2,000 field samples obtained during the 1976 epizootic in new jers ...1977409789
[value of the ouchterlony reaction in experimental trichinelliasis in swine].the double diffusion method after ouchterlony was employed for the diagnosis of swine trichinellosis. studied were sera of 12 experimentally infected pigs from the 15th to the 365th day after their treatment with moderate and massive doses of trichinella spiralis. the antigen used was an extract of freeze-dried decapsulated muscular trichinellae, obtained by tanner and gregory's method modified according to the institute's laboratory conditions. results showed that ouchterlony's double diffusion ...1977411237
eosinophilia in kenyan baboons (papio anubis) induced by trichinella spiralis and schistosoma mansoni.high primary doses of trichinella spiralis administered orally to kenyan baboons (papio anubis) induced a marked but unpredictable eosinophilia which started 2--3 weeks after infection and persisted as erratic waves for at least 6 months. low primary oral doses induced no eosinophilia but a later, high challenge gave an accelerated eosinophilic response, although the peak was lower than in high primary infection. intravenous injection of infective t. spiralis larvae resulted in a predictable, ra ...1977413084
trichinella spiralis and strongyloides ratti: immune interaction in adult rats. 1979421767
[trichinella spiralis infestation in children of the biaƂystok region]. 1979432012
trichinella spiralis: mediation of the intestinal component of protective immunity in the rat by multiple, phase-specific, antiparasitic responses. 1979437014
studies of macrophage function during trichinella spiralis infection in mice.studies were made to investigate the quantitative and functional changes which occur in peritoneal macrophage populations obtained from mice infected orally with trichinella spiralis larvae. c57bl/6 mice infected with t. spiralis larvae became parasitized with adult worms which were rejected from the intestine from 14 to 20 days after infection. infected mice developed a striking increase in peritoneal exudate cells, composed largely of macrophages, which was maximal at from 16 to 18 days after ...1979437839
trichinella spiralis in raccoons (procyon lotor) of tennessee. 1979448587
morphology of the advanced-stage larva of eustrongylides wenrichi canavan 1929, occurring encapsulated in the tissues of amphiuma in louisiana.larval nematodes identified as eustrongylides wenrichi canavan 1929, from cysts in the tissues of amphiuma means tridactylum cuvier in louisana were redescribed. the extent of differentiation of the sex organs was found to be greater than that of 3rd-stage dioctophyma renale, or of the infective stage of trichinella spiralis, and comparable with the late 4th-stage larva of secernentean (phasmid) nematodes.1979448605
trichinella spiralis: expression of rapid expulsion in rats exposed to an abbreviated enteral infection. 1979456465
trichinella spiralis: role of different life cycle phases in induction, maintenance, and expression of rapid expulsion in rats. 1979456466
[research on trichinella spiralis in rodents captured in the santos dock area]. 1979462116
purification of rodent eosinophils on discontinuous metrizamide gradients.methods are described for the purification of rat and mouse eosinophils. peritoneal exudate cells obtained from schistosoma mansoni- or trichinella spiralis-infected mice were plated on plastic dishes, and the nonadherent cells were centrifuged over discontinuous hypertonic metrizamide gradients. approximately 41% of those eosinophils present in the original preparations were recovered from the interfaces between 20% and 22% metrizamide at an average of 88% purity. peritoneal cells obtained from ...1979469262
transplantation of adult trichinella spiralis between hosts: worm survival and immunological characteristics of the host--parasite relationship.a technique for the transplantation of trichinella spiralis worms directly into the host intestine is described. infections established by the direct transfer of adult worms were essentially normal both in terms of their survival and reproduction and in their stimulation of, and susceptibility to, host immune responses. worms transplanted from nih mouse donors at intervals after infection had an equal ability to survive in the recipient, even when taken from the donor shortly before or during th ...1979471532
report 1977-1978 concerning trichinella spiralis studies in the netherlands. 1979473155
intestinal mast cells and globule leucocytes: role of the thymus on their presence and proliferation during a trichinella spiralis infection in the rat. 1979314934
influence of prostaglandin e2 (pge2) on t cells in mice infected with trichinella spiralis. 1977305170
identification and distribution of swine serum immunoglobins that react with trichinella spiralis antigens and may interfere with the enzyme-labeled antibody test for trichinosis.sera from trichinella spiralis digestion-negative swine contained variable amounts of two immunoglobins that reacted with t spiralis antigen in the indirect enzyme-labeled antibody test for trichinosis. one of these immunoglobins, detected by heavy chain-specific anti-swine immunoglobulin g (igg) conjugate, was removed by absorption with t spiralis larvae. a second immunoglobin, detected by heavy chain-specific anti-swine igm, was not removed by absorption with t spiralis larvae and increased in ...1979160765
immunity to trichinella spiralis. ii. expression of immunity against adult worms.thoracic duct lymphocytes or purified t or b cells obtained from specifically immunized (lewis x da)f1 hybrid rats can protect normal recipients against an oral challenge infection with t. spiralis. the immune cells increase the rate of expulsion of adult worms from the small intestine. immune tdl do not affect adult worm fecundity, as they do in other strains of rats, or the penetration and development of newborn larvae in muscle cells. irradiated f1 rats reconstituted with either immune tdl or ...1977304036
influence of enteric parasitism on hormone-regulated pancreatic secretion in dogs.the objective of this study was to test the hypothesis that enteric parasites affect pancreatic secretion in their host. pancreatic bicarbonate and protein outputs were studied in dogs with gastric and pancreatic fistulas to determine the secretory response to exogenously administered secretin and cholecystokinin and to intraduodenal stimulation with hydrochloric acid and sodium oleate to release endogenous hormones. bicarbonate and protein concentrations in pancreatic juice were measured prior ...1979474796
trichinella spiralis: immunity and inflammation in the expulsion of transplanted adult worms from mice. 1979477820
trichinella spiralis: an intracellular parasite in the intestinal phase.trichinella spiralis has been examined by electron microscopy after fixation in situ in the intestine of mice. the worms lie within the cytoplasm of cells of the intestinal mucosa and may occupy both absorptive and goblet cells. they cause little damage to host cells. a few worms have been seen protruding from tissue by sem techniques. these unusual observations suggest that the nematodes may be capable of exit and reentry into the epithelium.1979480074
the effect of the expulsion phase of trichinella spiralis on hymenolepis diminuta infection in rats.the effect of the intestinal changes brought about by the expulsion of trichinella spiralis in rats was studied in relation to the growth and survival of a concurrent infection with hymenolepis diminuta, a cestode not normally rejected by the rat in low-level infections. growth of h. diminuta was stunted in rats given t. spiralis just before, or after, infection with h. diminuta, the stunting being more pronounced when the cestode was given closer to the period of inflammation. there was no loss ...1979481909
[ultrastructural localization of cytoplasmic phosphatases in different developmental stages of trichinella spiralis. 3. localization of cytoplasmic phosphatases in the intestine of mature forms of trichinella spiralis]. 1979483810
[problem of geographical species of trichinella spiralis and their biological characteristics]. 1979483821
influence of parasitism on secretin-inhibited gastric secretion.this study tested the hypothesis that the inhibitory action of secretin on gastrin-stimulated gastric acid and pepsin secretion is comprised in animals harboring intestinal stages of the parasite trichinella spiralis. pentagastrin-stimulated acid and pepsin secretion, and the influence of secretin on these processes, were measured in dogs prepared with gastric fistulas and heidenhain pouches. dogs were studied before and after infection with 10(4) t. spiralis larvae/kg body weight. gastric secre ...1979484766
damage to trichinella spiralis newborn larvae by eosinophil major basic protein.purified eosinophil major basic protein damaged newborn larvae of trichinella siralis when added to in vitro cultures. damaged larvae were stiffened, immobile, and showed a granular appearance by light microscopy. larvae in control cultures and in cultures containing equimolar concentrations of other basic proteins failed to exhibit such damage.1979484767
cross-resistance between trichinella spiralis and angiostrongylus cantonensis in laboratory rats. 1979494711
ultrastructural localization of cytoplasmic phosphatases in intestinal form of trichinella spiralis (nematoda). 1979495208
eosinophils versus neutrophils in host defense. killing of newborn larvae of trichinella spiralis by human granulocytes in vitro.eosinophil leukocytes have been reported to have a major role in host defense against invasive, migratory phases of helminth infestations, yet the relative larvicidal abilities of eosinophils and neutrophils have not been thoroughly examined. this study examined the killing of newborn (migratory phase) larvae of trichinella spiralis during incubation by human granulocytes in vitro. the assay employed cultue of larvae with cells, sera, and reagents in microtiter wells with direct counting of surv ...1979500819
trichinella spiralis: comparison of stages in host intestine with those of an arctic trichinella sp. 1979510446
oral immunization of mice with metabolic antigens of trichinella spiralis larvae: effects on the kinetics of intestinal cell response including mast cells and polymorphonuclear eosinophils. 1979512763
intestinal phospholipase b activity in swine inoculated with trichinella spiralis.trichinella spiralis was studied in outbred swine to determine whether infection would cause an increase in intestinal phospholipase b (ec activity and in number of peripheral eosinophils. intestinal phospholipase b activities increased and were accompanied by eosinophilia. the response was similar to that found in rodents infected with helminth parasites, thus demonstrating that phospholipase b is not unique to rodent models and is probably part of the complex immune response of the ho ...1979525866
determination of the lethal dose of trichinella spiralis for germfree mice. 1979534952
influence of trichinella spiralis infection on development of sarcoma-180 ascites tumors.long-term infection of mice with trichinella spiralis has been shown to stimuate increased host protection aginst transplantable solid tumors. the present investionation was initiated to determine whether parasitized mice were similarly protected from induction and progression of an ascites tumor. icr/cd-1 mice were orally infected with 50, 100, 200, 300, or 400 t. spiralis larvae, and subsequently challenged intraperitoneally with 5 x 10(4) sarcoma-180 (s-180) ascites cells. animals were observ ...1979538817
efficacy of avermectins against trichinella spiralis in mice. 1979541496
studies on the isolation of the infective stages of trichinella spiralis and toxoplasma gondii from fresh and processed pork in egypt. 1979541599
the influence of cyclophosphamide on immunity in mice infected with trichinella spiralis. 1979543122
report on trichinella spiralis in denmark (1977-1978). 1979543131
report on trichinella spiralis status in greece. 1) epidemiologic data relating to trichinellosis in man, swine, other domestic and wild animals. 1979543137
[the dynamics of the immunocytoadherence test with trichinella spiralis-antigen in the experimental rabbit trichinellosis (author's transl)].the authors analysed the dynamics of the immunozytoadherence test in experimental trichinellosis. the evaluation was carried out by mixing the lymphocytes of the infected rabbits with sheep erythrocytes encoated with antigen trichinella spiralis. in three groups of infected rabbits (group i - 15 000 larves per rabbit, group ii - 20 000 larves per rabbit, group iii - 30 000 larves per rabbit) the examinations were performed 3, 6, 10, 20, 47, 82, 110, 140, 170 and 230 days after infection. it was ...1979543355
intestinal trichinella spiralis infection in germfree and conventiional mice treated with cyclophosphamide. 1979543975
presence of trichinella spiralis in free-living red foxes (vulpes vulpes) in sweden related to trichinella infection in swine and man. 1979546215
effects of immune serum and cells on newborn larvae of trichinella spiralis.serum and cells, collected from mice immunized by infection either with newborn larvae (nbl) or per os with infective larvae of trichinella spiralis, were passively transferred to mice which were challenged with nbl. serum always gave very strong protection if given before challenge but not if given within 2 h after challenge. cells from mice immunized with nbl also gave good protection, whereas those from mice immunized per os did not. if nbl were incubated in serum from immunized mice their in ...1979551376
altered intestinal fluid movement in response to trichinella spiralis in immunized intestinal fluid movement was measured in immunized and non-immunized rats infected with the enteric stages of the nematode, trichinella spiralis. animals were studied 30 min, 5 days and 30 days after receiving infective larvae. net water movement across the mucosal surface of the gut was measured in vivo by perfusing a cannulated segment (approximately 30 cm) of proximal small intestine with an isotonic solution containing a nonabsorbable marker, 14c polyethylene glycol, at a rate of 0.5 ml ...1979551380
trichinosis in bears of western and northcentral united bears (ursus americanus) from 10 states were examined for trichinella spiralis during the 1970-1975 period. trichinae were found in 14 (3.1%) of 454 bears examined. infected bears were found from california, seven (13.2%) of 54; idaho, one (2.3%) of 44; and wisconsin, six (3.8%) of 163. trichina counts per gram of tissue obtained by the artificial digestion-baermann method ranged from 1390 to 0.02. six california bears and one from wisconsin contained more than one trichina per gram, a lev ...1977560797
ultrastructural observations on the in vitro interaction between rat eosinophils and some parasitic helminths (schistosoma mansoni, trichinella spiralis and nippostrongylus brasiliensis).rat eosinophils form an intimate association with the surfaces of parasitic helminths, in vitro, in the presence of immune serum. the parasite presents a non-phagocytosable surface to the cell. the initial response of the eosinophil is degranulation which leads to the formation of large cytoplasmic vacuoles. peroxidase, an enzyme localized in the matrix of the crystalloid secretion granules, is discharged into these vacuoles as a consequence of degranulation. the vacuoles eventually become conne ...1977564249
the indirect rosette-forming cells in the blood of rabbits infected with trichinella spiralis. 1977564577
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