Publications

TitleAbstractYear
Filter
PMID
Filter
physiological basis of host susceptibility of florida mosquitoes to dirofilaria immitis. 1975441
dirofilaria immitis (dog heartworm) as a pulmonary lesion in humans.dirofilaria immitis, the dog heartworm, has been identified in the pulmonary granulomas of 5 patients from the greater charleston area; this is the largest series of such cases from one medical center. the patients had no pulmonary symptoms. on roentgenogram the lesions were all about 2 cm in size, of uniform light opacity, and located near the pleural surface. thoractomy was performed in each instance because of the possiblity of carcinoma. the association of granuloma formation, pulmonary infa ...19765063
increased pulmonary vascular pressor response to hypoxia in highland dogs. 197714334
distribution of acid phosphatase activity in the larval stages of wuchereria bancrofti, brugia malayi, b. pahangi and dirofilaria immitis in the mosquito.the histochemical distribution of acid phosphatase in microfilariae and in the larval stages of four mosquito-borne filariae: wuchereria bancrofti, brugia malayi, b. pahangi and dirofilaria immitis was studied using naphthol as-tr-hexazonium technique and light microscopy. accurate differentiation between microfilariae of the four species could be made on the basis of their patterns of acid phosphatase activity. in contrast to microfilariae in the blood, the larval stages in the mosquito exhibit ...197716368
dirofilaria immitis and its potential mosquito vectors in central new york state.screening of 25,822 dog blood samples indicated approximately a 1% infection rate with dirofilaria immitis. dipetalonema reconditum microfilariae were found in approximately 2% of 1,876 feral dogs examined. laboratory experimentation indicated that 6 of 10 local mosquito species examined allowed successful extrinsic incubation of d immitis. indices of experimental infection indicated aedes triseriatus and anopheles quadrimaculatus were excellent hosts for d immitis, but other factors considered, ...197720828
presumed dirofilaria immitis infections in natural mosquito populations of connecticut. 197832395
observations on the early death experienced by dirofilaria immitis-infected mosquitoes (diptera: culicidae). 197935614
hexokinase of the adult dog heartworm, dirofilaria immitis.1. dirofilaria immitis hexokinase was relatively heat stable and had a ph optimum range between 7.8 and 8.2. 2. mean vmax was 0.40 +/- 0.10 (s.d.) mumole/min/100 mg of worm. 3. mean km values were 0.32 mm for glucose, 0.86 mm for fructose and 0.39 mm for atp. 4. glucose-6-phosphate was not a strong product inhibitor. 5. starch gel electrophoresis demonstrated at least three isozymes.197745524
analysis of serum proteins, using agarose electrophoresis in normal dogs and in dogs naturally infected with dirofilaria immitis.the electrophoretic pattern of 130 serum samples from clinically normal dogs was evaluated, using agarose as the supporting matrix. the relative mobility of each globulin fraction in relationship to the mobility of albumin was determined in 70 dogs, and nomenclature based on the mobilities (rf values) was proposed. biuret protein determinations were done, and relative and absolute values of each serum protein fraction were determined. changes in the fractions of serum proteins were evaluated in ...197770182
specific allergic sensitsation to filarial antigens in tropical eosinophilia syndrome.reaginic antibodies to antigens from the human filarial parasites wuchereria bancrofti and brugia malayi and the animal parasite dirofilaria immitis were studied by histamine release from basophils in 7 patients with tropical eosinophilia (t.e.) and 18 patients with other manifestations of filarial infection (lymphatic changes or symptomless microfilaraemia). all the patients had antibodies to all three filariae but t.e. patients were more highly sensitised. t.e. patients responded more to antig ...197986883
intraarticular microfilariae in laboratory animals. 1979114182
inhibition of dirofilaria immitis in gregarine-infected aedes aegypti: preliminary observations. 1979115926
glycolytic end products of the adult dog heartworm, dirofilaria immitis.1. adult dog heartworms remained alive and motile for 24 hr without oxygen present and with only glucose available as a substrate. 2. lactate accounted for 55% of the carbon from the 1-14c-glucose utilized in 1 hr and 14co2 for 1.9%. 3. only traces of 14c were found in glycogen and no net accumulation of acetate was demonstrated. 4. dirofilaria immitis resembles litomosoides carinii in the percent of utilized glucose appearing as lactate but is more akin to brugia pahangi and dipetalonema viteae ...1979122581
hematologic and radiographic changes in cats after inoculation with infective larvae of dirofilaria immitis.hematologic and radiographic findings in 15 domestic cats inoculated with 25, 100, or 200 to 400 infective larvae of dirofilaria immitis and in 5 uninoculated cats were compared. eosinophilia and leukocytosis developed 3 to 5 months after inoculation; packed cell volume and hemoglobin values were similar for inoculated cats and controls. changes detected in radiographs of inoculated cats were: (1) increased visualization of the pulmonary arteries; (2) right-side cardiac enlargement; and (3) diff ...1976130366
dirofilaria immitis (heartworms). 1976134023
inhibition of lactate dehydrogenase activity from dirofilaria immitis by suramin.lactate dehydrogenase from adult d. immitis was partially purified and characterized. the molecular weight of the enzyme was determined to be 130 000. the specific activity of the lactate dehydrogenase was 4.1 u/mg in the direction of nadh-oxidation and 0.38 u/mg protein in the direction of nad-reduction. the michaelis constants were determined to be 0.028 mm and 0.9 mm for nadh and nad, respectively. suramin was found to be a potent inhibitor of the lactate dehydrogenase activity. the inhibitio ...1979231858
letter: human pulmonary dirofilariasis: entry method of infective larvae. 1975238798
a shock syndrome related to administration of diethylcarbamazine citrate, producing electrocardiographic changes in a dog with microfilariae of dirofilaria immitis. 1977245205
incidence of heartworm (dirofilaria immitis) infection in memphis, tennessee. 1979257970
[immunological diagnosis of filariosis in persons returning from tropical countries and in european and indigenous inhabitants of endemic areas (author's transl)].serum samples from persons who lived in areas where onchocerciasis occurred or who had filariasis were examined with the complement fixation test and the indirect hemagglutination test for the presence of antibodies against crude extracts from dirofilaria immitis, onchocerca volvulus, dipetalonema viteae, and ascaris suum. the results could be interpreted as follows: 1. the indirect hemagglutination test was more sensitive than the complement fixation test for the demonstration of antibodies in ...1977271633
glycerol metabolism in the adult dog heartworm, dirofilaria immitis.1. when adult dirofilaria immitis were incubated up to 60 min in a medium containing physiological concentrations of glycerol and glucose, the mean amount of free glycerol present did not change significantly. 2. [14c]2-glycerol disappeared from media in which 1 g heartworms were incubated at a linear rate of about 0.7 mumol/hr/g during the first hour. 3. 85-95% of the radioactivity in the folch extract remained in the aqueous phase. 4. phosphoglycerides and diacylglycerols accounted for better ...1979318317
lipid synthesis in the adult dog heartworm, dirofilaria immitis.1. incorporation studies with three labelled substrates--[14c]2-glycerol, [14c]1-acetate and [14c]1-oleic acid--demonstrated that adult dog heartworms can synthesize all classes of complex lipids present, including free cholesterol. 2. diacylglycerols and phosphoglycerides were most rapidly labelled regardless of the precursor employed. 3. 14c from glycerol was found in the aqueous phase of saponified lipids, whereas that from oleic acid was in the fatty acid portion. 4. tag from acetate was pre ...1979318318
sensitivity and specificity of skin reactivity to brugia malayi and dirofilaria immitis antigens in bancroftian and malayan filariasis in the philippines.saline antigen extracts of microfilariae, adult worms and third-stage larvae of subperiodic brugia malayi maintained in gerbils were prepared for use as skin test reagents. patients were studied on three different islands in the philippines, one endemic for bancroftian filariasis (sorsogon, luzon), another endemic for malayan filariasis (palawan) and the third without endemic filariasis (cebu). a dose-response curve was established initially in patients with bancroftian filariasis: thereafter 1. ...1977322516
immunofluorescent reactions with microfilariae: 1. diagnostic evaluation.microfilariae have been evaluated as antigen for the indirect immunofluorescent test in the diagnosis of filariasis. sonicated, unlike whole, microfilariae present no problems in handling on a slide. the cytoplasmic antigen that is exposed by sonication, unlike the sheath or cuticular antigen, reacts with filariasis sera irrespective of whether or not there is a detectable microfilaraemia. the cytoplasmic antigen of microfilariae of various species was marginally superior to dirofilaria adult wo ...1977339419
"a most certaine and true relation of a strange monster or serpent found in the left ventricle of the heart of john pennant, gentleman, of the age of 21 years". 1977339428
immunodiagnosis of parasitic zoonoses: comparative efficacy of three immunofluorescence tests using antigens purified by affinity chromatography.three immunofluorescent antibody assays were developed during this study: the direct (dfat) and indirect (ifat) fluorescent antibody tests using frozen worm sections, and the cyanogen bromide indirect fluorescent antibody test (cnbr-ifat) using helminth antigens purified by affinity chromatography bound on to commercially prepared cnbr-sepharose 4b beads. purified antigens used in the cnbr-ifat gave greater specificity and sensitivity than either the dfat or ifat. dirofilaria immitis, toxocara c ...1978354114
[the incidence of dirofilaria immitis in dogs of havana city].the significance of the knowledge of the incidence of dirofilaria immitis in the dog is emphasized since dirofilariasis is a zoonosis which produce subcutaneous tumors which clinical-etiological diagnosis is very difficult. adult forms are often located in the skin. the percentage of parasitized dogs found in the havana city is reported. one-hundred-and-two necropsies of gadder dogs depicted that 6,86% of them had dirofilaria immitis. results were negative in the remaining 93,13%.1977354645
a heated centrifuge for orientation of electron microscope specimens. 1978364776
indirect fluorescent antibody test in occult dirofilariasis.indirect fluorescent antibody titers to dirofilaria immitis microfilaria (ifa-mf) and peripheral eosinophilia were recorded from 15 to 52 months in ten experimentally infected dogs with occult dirofilariasis (heartworm infection without microfilaremia). five dogs which were experimentally sensitized with d immitis microfilaria did not exhibit microfilaremia after inoculation with infective-stage larvae. in three other dogs, microfilaremia suddenly ceased after 4 to 7 months. in these three dogs, ...1979382922
distribution and diagnosis of dirofilariasis and toxocariasis in australia. 1979391207
studies on endoparasites of the black bear (ursus americanus) in the southeastern united states.examination of 53 black bears (ursus americanus) from six states in the southeastern united states revealed at least 17 species of endoparasites, including sarcocystis sp., spirometra mansonoides (spargana), macracanthorhynchus ingens, ancylostoma caninum, arthrocephalus lotoris, baylisascaris transfuga, capillaria aerophila, capillaria putorii, crenosoma sp., cyathospirura sp., dirofilaria immitis, gnathostoma sp., gongylonema pulchrum, microfilariae, molineus barbatus, physaloptera sp. and str ...1978418189
survey for dirofilaria immitis in mecklenburg county, north carolina. 1979438038
the effects of various carbohydrate diets on aedes aegypti infected with dirofilaria immitis. 1979438527
pulmonary lesions due to dirofilaria immitis (dog heartworm). report of four cases with radiologic findings.chest radiographs of 4 patients with dirofilaria immitis (dog heartworm) revealed solitary, small, peripheral, noncalcified nodular lesions. the pulmonary lesions were apparently produced secondary to lodging of the parasite in peripheral pulmonary vessels. none of the patients had symptoms referable to the heartworm lesions. needle aspiration in 2 patients revealed a nonspecific inflammatory lesion.1979441308
brugia pahangi and dirofilaria immitis: experimental infections in the ferret, mustela putorius furo. 1979446585
immunological and physicochemical properties of a highly purified allergen from dirofilaria immitis.allergen in crude extract of dirofilaria immitis was purified and separated from igg-inducing antigens by a combination of deae-sephadex a-50 chromatography, sephadex g-200 gel filtration and starch gel zone electrophoresis. the purified preparation was proved to be one protein band by sodium dodecyl sulfate polyacrylamide gel (sds-gel) electrophoresis and one precipitin arc by immunodiffusion. the molecular weight of the purified allergen was estimated to be approximately 20,000 by gel filtrati ...1979468388
nodular skin disease associated with dirofilaria immitis infection in the dog.three dogs with dirofilariasis had a dermatologic syndrome, characterized by pruritus and multifocal nodules which tended to ulcerate. the cutaneous nodules revealed angiocentric pyogranulomatous inflammation with variable numbers of eosinophils. microfilariae were often present in the blood vessels surrounded by the pyogranulomatous process. therapy for dirofilariasis resulted in complete resolution of the dermatitis.1979477322
dirofilaria immitis: cell-mediated and humoral immune responses in experimentally-infected dogs. 1979489233
culture systems for the maintenance and development of microfilariae. 1979496468
dirofilaria in the abdominal cavity of a man in japan.a case of human dirofilariasis of the abdominal cavity is reported from japan. the patient, a 74-year-old man, died of liver cancer; postmortem examination revealed a granulomatous mass on the mesentery. in histologic sections there were cross-sections of a mature female nematode identified as a dirofilaria. the cuticle had a smooth surface and consisted of four distinct layers. the inner cuticular layer had internal lateral longitudinal ridges, and the musculature of the body wall was of the hi ...1979507286
efficacy of avermectin b1a against microfilariae of dirofilaria immitis.avermectin b1a given at a dose level of 0.05 or 0.1 mg/kg of body weight caused rapid removal of dirofilaria immitis microfilariae from the blood of dogs with heartworm infections. if the adult worms were also killed with an arsenical (melarsoprol), the removal of microfilariae was permanent.1979507489
microfilariae in the ejaculate of a dog. 1979514248
dirofilaria immitis infection in foxes and coyotes in indiana.between october 1976 and january 1977, carcasses or hearts and lungs from 202 wild foxes and coyotes in indiana were collected to determine the prevalence of dirofilaria immitis infection. three of 113 (2.7%) red foxes (vulpes fulva), 3 of 81 (3.7%) gray foxes (urocyon cinereoargenteus), and 1 of 8 (12.5%) coyotes (canis latrans) were infected with d immitis. an average of 5 worms (range, 1 to 10) were recovered from foxes and 11 worms were recovered from the coyote. worms from the coyote were o ...1979521369
scintigraphic evaluation of pulmonary perfusion in dogs experimentally infected with dirofilaria immitis.pulmonary arterial perfusion was evaluated by perfusion lung scans in ten dogs experimentally infected with heartworm. after larval inoculation, scans were done once a month for 11 months. in 8 of 10 dogs, pulmonary arterial perfusion deficits were detected. the perfusion deficits involved the left cranial, right cranial, and right caudal lung lobes. generally, there was a poor correlation between vascular abnormalities detected on the survey thoracic radiographs and the perfusion deficits detec ...1979525864
the effectiveness of levamisole hydrochloride in the treatment of adult dirofilaria immitis.dogs infected with d. immitis were treated with oral levamisole hydrochloride at various dose rates over different durations. clinical toxicity, haematological and biochemical parameters, body weight and food intake were recorded and filarial mortality estimated at autopsy. all filariae were dead in dogs treated at 10 mg/kg body weight twice daily (12 hourly) for 14 days, with minimal clinical toxicity being seen during the treatment period.1979543826
high dipetalonema reconditum microfilarial counts in two dogs.dipetalonema reconditum microfilarial counts of 509 and 932/ml of blood, respectively, were found in 2 dogs thought to have been infected with dirofilaria immitis. the high counts were attributed to a state of immunosuppression. it was concluded that microfilarial width is a more reliable criterion that microfilarial numbers for the differentiation of d immitis and d reconditum infections. for reliable width measurements, it is necessary to use the modified knott or polycarbonate filter techniqu ...1978566740
the prevalence of heartworms (dirofilaria immitis) in dogs from indiana. 1978569196
diethylcarbamazine citrate for prevention of heartworm (dirofilaria immitis) in the california sea lion (zalophus californianus). 1977585265
dirofilaria immitis from the eye of a dog in arkansas. 1977592053
pulmonary dirofilariasis: report of a human case.dirofilaria immitis (dog heartworm) principally infests canine hosts. however, human pulmonary dirofilariasis is being reported with increasing frequency, and the following case illustrates essential features of the disease. it typically presents as a solitary pulmonary nodule without symptoms and invariably requires pulmonary resection to differentiate it from primary or secondary malignancy.1977594944
filaria in the vitreous of the eye of man in peninsular malaysia.an active worm was seen in the right eye of a 62-year-old man in malaysia. the worm was behind the lens and attached at one end to some vitreous fibers. it was tentatively identified as an immature dirofilaria immitis. there appear to be only five previous authentic reports of filariae in the vitreous.1977596511
density gradient separation of lymphocytes, eosinophils, and microfilariae from blood of dogs infected with dirofilaria immitis. 1977596710
heartworm heart disease. 1977602865
dirofilaria immitis: effect on the longevity of aedes trivittatus. 1978627272
cuticular morphology of five species of dirofilaria: a scanning electron microscope study.cuticular markings of five species of dirofilaria were examined by sem. variations in the patterns on the en face view were observed among the species. transverse striations were observed on the cuticles of all five species, but longitudinal ridges were lacking on dirofilaria immitis, the type species of the subgenus dirofilaria. they were present on the other four species, dirofilaria repens, dirofilaria tenuis, dirofilaria corynodes, and dirofilaria magnilarvatum, members of the subgenus nocht ...1978627947
dirofilaria immitis: experimental infections in the ferret (mustela putorius furo).the ferret, mustela putorius furo, was found to be susceptible to dirofilaria immitis infection when exposed to low (14) or high (280-420) numbers of infective larvae harvested from aedes aegypti. eight ferrets (half of them cortisonized) were inoculated subcutaneously with 14 larvae each. all of them were subsequently found to harbor d. immitis in the heart, and all but one of them had worms of both sexes. six of these ferrets were examined for microfilaremia at 31 to 35 weeks after inoculation ...1978627949
laboratory observations on the insusceptibility of raccoons to dirofilaria immitis.two raccoons, procyon lotor, were exposed to dirofilaria immitis by subcutaneous injection of infective third stage larvae obtained from experimentally-infected aedes trivittatus. nematodes were not recovered from either raccoon when examined at necropsy 223 and 254 days postexposure. large numbers of adult d. immitis were found in six dogs used as controls. these data indicate that raccoons cannot support the development of d. immitis.1978633513
dirofilaria immitis: a cause of human intra-ocular infection. 1978689747
heartworm infected dogs in the netherlands.heartworm infected small animal patients are seldom seen in the netherlands, because the parasite's life cycle cannot be completed in this climate. we report here four cases of the disease in dogs brought to the netherlands from endemic heartworm areas. the initial diagnosis was based upon this knowledge and clinical signs (low exercise tolerance and coughing). the diagnosis was confirmed by the radiographic finding of variable pulmonary artery enlargement, the electrocardiographic finding of ri ...1978705753
rapid decrease of precipitating and reaginic antibodies in dirofilaria immitis-infected dogs which develop severe adverse reactions following treatment with diethylcarbamazine.dirofilaria immitis-infected dogs were treated with diethylcarbamazine. measurement of the level of igg precipitating antibody was carried out by counterimmunoelectrophoresis and that of ige by passive cutaneous anaphylaxis in pre-treatment and post-treatment serum samples. in dogs showing severe to moderate adverse reactions to the drug there were pronounced decreases of both antibodies to a "metabolic" antigen prepared from the medium in which adult female worms had been incubated. these antib ...1978727319
trial of avermectin b1a, mebendazole and melarsoprol against pre-cardiac dirofilaria immitis in the ferret (mustela putorius furo).avermectin b1a was found active against the pre-cardiac stage of dirofilaria immitis in ferrets. the drug was given orally, at 0.2 mg/kg, on days 38--42 of infection. at necropsy, 5 1/2 months after inoculation, worms were almost totally absent from the hearts of these ferrets. the efficacy of melarsoprol against developing dirofilaria, which has been demonstrated in dogs by other workers, was demonstrated in ferrets given oral doses, at 100 mg/kg, on days 38--42 of infection. the reported effic ...1978739297
[a case of pulmonary dirofilariasis presenting pulmonary infarction caused by dirofilaria immitis (author's transl)]. 1978739699
cell mediated and humoral immune response in tropical eosinophilia. 1978744632
efficacy of avermectins against dirofilaria immitis in dogs. 1978752054
case records of the massachusetts general hospital. weekly clinicopathological exercises. case 13-1979. 1979763304
nematode sense organs. 1976769503
factors that affect the intradermal test in diagnosis of filariasis in egypt. 1976801636
pulmonary dirofilariasis: another coin lesion.a 67-year-old woman with a long history of debilitating rheumatoid arthritis developed a peripheral coin lesion in the lower lobe of the left lung. a wedge resection was done and pathologic study revealed noncaseating granuloma secondary to rheumatoid infection with dirofilaria immitis, a nematode. although rare, canine dirofilariasis should be considered in the differential diagnosis of coin lesions.1977850826
adult heartworms in arteries and veins of a dog.a 5-year-old terrier-type dog with a 3-week history of progressive lameness, swelling, and pain in the left hindlimb suddenly became paralyzed in the right hindlimb. because of a poor prognosis, the dog was euthanatized. necropsy revealed mature heartworms (dirofilaria immitis) in the femoral arteries as well as in the right side of the heart and pulmonary arteries. extensive ischemic necrosis in the muscles of the hindlimbs was attributed to occlusion of the femoral arteries by heartworms.1977858687
preliminary studies on the transplantation of adult dirofilaria immitis into laboratory rodents. 1977869615
evaluation of a polycarbonate filter for the detection of microfilaremia in dogs in central michigan.several diagnostic techniques were used in determining the prevalence of microfilaremia in 479 dogs entering the holding facility for research animals at michigan state university. the modified knott test and cellulose filter procedures were initially applied, but persistent difficulties with the cellulose filter system prompted evaluation of the use of clear polycarbonate filters. this procedure was found to be equally as sensitive as the modified knott test and more sensitive than the microhem ...1977870465
prevalence of dirofilaria immitis infection in dogs from a humane shelter in ohio.hearts of 500 dogs more than 1 year old from a humane shelter in columbus, oh, were examined for dirofilaria immitis infection. peripheral blood from dogs with worms in the heart was examined for microfilariae. dirofilaria immitis adults were found in 24 (4.8%) hearts. the number of worms in infected hearts were: 19 (1 dog), 6 (2 dogs), 5 (1 dog), 4 (2 dogs), 3 (1 dog), 2 (9 dogs), and 1 (8 dogs). of the 24 infected dogs, 4 had only male worms, 8 had only female worms, and 12 had worms of both s ...1977870466
efficacy of levamisole resinate against dirofilaria immitis in dogs. 1977882096
dirofilaria immitis recovered from a horse. 1977893220
susceptibility of dogs with heartworm disease to hypoxia.dogs with dirofilaria immitis microfilariae and early radiographic pulmonary artery changes, but without pulmonary hypertension or clinical signs of heartworm disease, were studied. an exaggerated pulmonary hypertensive response was found in these dogs if subjected to 10% inspired oxygen. the mean pulmonary artery pressure of control dogs was increased from base line (prehypoxia control) of 15.8 +/- 2.3 (sem) mm of hg to 20.2 +/- 2.3 during hypoxia, and the mean pulmonary pressure of dogs with h ...1977921031
dirofilariasis in iowa coyotes.(dirofilaria immitis) were found in eight of 220 (3.6%) coyotes (canis latrans) collected from fur buyers in adams, carroll, cass, and warren counties in southwestern iowa. infections ranged from one to 23 worms per coyote.1976933306
studies on hemagglutination test on filariasis. i. the fractionation and purification of antigens by column chromatography and disc electrophoresis.the fractionation of antigens for hemagglutination test from adult worms of dirofilaria (d.) immitis was carried out by defatting with diethylether, sonication, centrifugation, gel-filtration on sephadex g-100 column, deae cellulose column chromatography, saturation with ammonium sulfate and disc electrophoresis. an antigen fpsd4 thus obtained, showed potent ha activity against sera from patients infected with wuchereria (w.) bancrofti. but it was also reactive with normal sera. after eliminatio ...1976933367
dirofilaria immitis and dipetalonema reconditum infections in oklahoma dogs. 1976943387
incidence of canine heartworm (dirofilaria immitis) in malaysia.a total of 764 adult dogs were examined for microfilariae and adult worms of d immitis and 197 (25-8 per cent) were found to be infected. direct blood examinations revealed only 47-2 per cent of the infected dogs whereas the blood serum examination detected 57-8 per cent of them. these results showed that the absence of circulating microfilariae could not be relied upon to be an accurate indication of the absence of patent heartworm infection. the average number of heartworms per dog was 5-5 wit ...1976943885
analysis of the microfilarial periodicity of dirofilaria immitis.microfilarial periodicity displayed by dogs infected with dirofilaria immitis was analyzed using the methematical model proposed by sasa and tanaka (s.e. asian j. trop. med. and pub. health 4, 1974, 518-536) except that pearson's product-moment correlation test was substituted for their chi-square analysis to estimate goodness of fit. samples were drawn at 3 hour intervals for periods of 24 or 48 hours in a series of 10 studies conducted on 4 dogs. no significant differences were observed in mic ...1976954440
levamisole resinate as a dirofilaria immitis microfilaricide in dogs.dogs infected naturally or experimentally with dirofilaria immitis were given levamisole resinate at the rate of 5.5 or 11 mg/kg of body weight/day for 10 days. all dogs had been treated with thiacetarsamide sodium approximately 6 weeks earlier. when given at the dosage of 5.5 mg/kg for 10 days, levamisole resinate was not effective as a microfilaricide in either naturally or experimentally infected dogs. microfilaria counts were reduced in all dogs at this dosage, but never to zero. in all case ...1976956014
prophylactic activity of mebendazole against dirofilaria immitis in dogs. 1976978377
changes in hookworm distribution in surinam.during the months may-july, 1974, a follow-up investigation was carried out on hookworm infections in dogs and cats in order to study changes in the hookworm distribution in surinam since 1967. fifty-two cats and 152 dogs were examined for the presence of helminths in the oesophagus, small intestine, coecum and heart. in total 15,942 helminths were isolated; most of these (14,006) were hookworms belonging to the species ancylostoma caninum, a. tubaeforme, a. ceylanicum and a. braziliense. the av ...1976987625
a new immunodiagnostic test in onchocerciasis.the radioallergosorbent (rast) technique was used as a diagnostic test for onchocerciasis. ige antibodies for dirofilaria immitis antigen were found in thirty-one of fifty-seven (54%) affected patients.19761016289
killing effect of normal peritoneal exudate cells in guinea pigs on microfilariae of dirofilaria immitis evoked by passive transfer of immune humoral factor.parasiticidal activity of normal peritoneal exudate cells on microfilariae of dirofilaria immitis in diffusion chambers implanted into normal guinea pigs was evoked by intraperitoneal passive transfer of anti-d. immitis serum. the immune serum was fractionated into supernatant and sediment by ammonium sulfate precipitation. the parasiticidal effect was reproduced with the supernatant and, to a less extent, with the sediment. anti-d. immitis serum from the animals sensitized 5 days before was als ...19761030746
a comparison of the efficiency of the nuclepore and millipore filtration systems for detecting microfilariae.using brugia pahangi or dirofilaria immitis as the test organisms no significant difference could be detected between nuclepore and millipore filters. it was found that 0.7% of microfilariae passed through the millipore and 1% through the nuclepore filters. no microfilariae were lost from the nuclepore membrane during the staining process.19761030840
[significance of passive hemagglutination and its prospectives in lymphatic filariasis].the authors analyze the data concerning 219 sera, that they have tested in passive hemagglutination, with as antigen a dirofilaria immitis proteic extract, in french polynesia. besides its light sensitivity, this method does appear very interesting. it points out: --first, that there is a gaussian distribution of the results found at various dilutions, both by "filarian" and "non filarian" people. therefore, this distribution is a feasible and practical parameter for evaluation of the filariasis ...19761037386
survey of dirofilaria immitis infection among dogs at fort dix & mcguire afb, new jersey. 19761048799
studies of immediate hypersensitivity in a patient with acanthocheilonema perstans filarial infection.a 25-year-old white female returned from west africa with a two-year history of epidosic swelling, pruritus, and pain in a wrist, associated with peripheral eosinophilia. serologic and immediate skin tests with dirofilaria immitis antigen were positive, and blood smears transiently showed microfilariae of acanthocheilonema perstans after the patient had been treated with diethylcarbamazine. before treatment, both the serum concentration of ige and the eosinophil content of arylsulfatase, an enzy ...19751079219
a rapid batch method for the production of specific fluorescein isothiocyanate-labeled globulins to dirofilaria immitis microfilaria.a rapid, reproducible method for the production of specifically labeled anti-dirofilaria immitis microfilaria (mff) globulins (mag) has been devised. these labeled antibodies have made the detection of d immitis in serum possible by a fluorescent-antibody technique.19751089371
letter to the editor: dirofilaria immitis survey in new york state. 19751126172
dirofilaria immitis (dog heartworm) as a cause of pulmonary infarction in man. 19751128003
tropical eosinophilia. a human model of parasitic immunopathology, with observations on serum ige levels before and after treatment.the diverse clinical syndromes characterized by asthmatic symptoms, transient pulmonary infiltrates, and eosinophilia have tended to obscure the specific association of one such entity with filarial infections. serum ige levels were determined before and after therapy in a group of well-characterized patients with tropical eosinophilia (te), studied earlier in singapore. the mean serum ige level in 14 cases before treatment with diethylcarbamazine was 2,355 ng. per milliliter, with a trend but s ...19751138016
human pulmonary dirofilariasis. a case report and review of the literature.a case of pulmonary dirofilariasis in a 48-year-old woman is presented. this rare pulmonary disorder is caused by dirofilaria immitis, the canine heartworm. a review of the literature revealed 40 documented cases, most of which have occurred in the united states within the past 10 years. the incidence of pulmonary dirofilariasis appears to be increasing; thus, this entity represents an important zoonosis and indicates a need for familiarity with the pathologic features of the lesions and the mor ...19751163896
solitary and bilateral pulmonary nodules due to dirofilaria immitis. 19751163897
separation of dirofilaria immitis allergen from the igg-inducing antigens.allergen in crude extract of dirofilaria immitis was purified and separated from the igg-inducing antigens by a combination of deae-sephadex a-50 chromatography and sephadex g-200 gel filtration. the molecular weight of the purified preparation was estimated to be approximately 20,000 by gel filtration. the carbohydrate content of the preparation was apparently low, about 2%. rats immunized with the allergenic fraction developed only a homocytotropic antibody and no hemagglutination antibody.19751165610
dirofilaria immitis: ultrastructural aspects of oocyte development and zygote formation. 19751168584
prevalence of dirofilaria immitis in a stray dog population in western new york.in a survey in 1973 undertaken to determine the prevalence of dirofilaria immitis in 100 dogs from a public pound in western new york, 2 dogs were found to be positive. microfilariae of dipetalonema sp were not present. hearts and pulmonary blood vessels were dissected for adult worms, and blood samples were examined for microfilariae, using a modified knott technique. although adult heartworms and microfilariae have been recovered from wild foxes, coyotes, and wolves in new york, this is the fi ...19751170797
cell-mediated immunity to dirofilaria immitis.cell-mediated immunity to dirofilaria immitis (di) in guinea pigs was confirmed by the migration inhibition test (mit), the blast transformation test (btt), the delayed skin reaction, and the skin reaction by passive transfer with sensitized peritoneal exudate (pe) cells. all migration inhibition (mi) positive cases were always associated with positive skin reactions and two cases showed positive skin reactions without mi. the cellular antibody confirmed by mit first appeared on the 4th day afte ...19751172086
experimental infection of cats with dirofilaria immitis.natural and experimental infections of cats with dirofilaria immitis have been reported. experimental infections of d. immitis in cats with the subsequent detection of microfilaremia and immediate skin hypersensitivity to antigen to d. immitis were produced. cutaneous nodules and chylothorax were also detected in some infected cats. adult worm recoveries were low and dead worms were found in some cats indicating the unsuitability of the cat as a host for d. immitis. however, one successful mosqu ...19751172533
Displaying items 1 - 100 of 1901