| laboratory and field assessment of the molluscicidal activity of gogo (entada phaseoloides) against the amphibious snail intermediate host of schistosoma japonicum. | a molluscicidal fraction occurs naturally in the bark of a vine (gogo in tagalog), entada phaseoloides, which grows indigeneously and abundantly in the philippines. butanol fraction of the methanol extracts of the bark was most toxic against oncomelania quadrasi with the lc50 of 3.6-5.8 ppm. analytical work on the butanol fraction by thin layer chromatography indicated that the active molluscicidal agents contained at least two kinds of saponins. the potency of e. phaseoloides remained rather st ... | 1977 | 24770 |
| schistosoma japonicum: anti-dna responses, serum cryogelatification, and cryoprecipitation phenomena in infected rabbits. | | 1977 | 69548 |
| lymphocyte responsiveness to phytohemagglutinin and to worm and egg antigens in human schistosomiasis japonica. | using a whole blood culture technique, lymphocyte responsiveness was assayed as 3h thymidine incorporation in 41 individuals infected with schistosoma japonicum. in comparison with controls, response to phytohemagglutinin (pha) was suppressed but was unrelated to egg excretion levels or duration of infection. reactivity to whole worm antigens was significantly greater in individuals with a higher level of egg excretion and presumably greater infection intensity. the response to egg antigens sign ... | 1979 | 86307 |
| the efficacy and toxicity of s72055 in experimental chemotherapy of schistosomiasis japonica. | | 1978 | 104835 |
| schistosomiasis japonica in barrio san antonio, basey, samar in the philippines: ii. quantitative fecal examination and circumoval precipitin tests. | an improved quantitative stool examination technique (mfct) and two variations in the performance of the circumoval precipitin test, one using whole serum (scopt) and the other employing the eluate from finger prick blood dried on filter paper (fpcopt), were evaluated in a field study to detect infection with s. japonicum among residents of an endemic barrio in samar. the sensitivity of scopt was above 90%, that of mfct was between 80 to 90%, while that of fpcopt was only about 50%. intensity of ... | 1978 | 107595 |
| schistosomal glomerulopathy. | | 1979 | 119087 |
| experimental renal disease due to schistosomiasis. | although there is a marked variability in the development of renal lesions among individual animal models of schistosomal infections, much has been learned about the mechanisms leading to renal injury. the lesions in s. mansoni and s. japonicum infections correspond quite closely to the immune complex type of lesions, with complement involvement. the main antigens involved seem to be polysacharides of worm-gut origin, but participation of other antigens (including soluble egg antigens) cannot be ... | 1979 | 119088 |
| the pathogenesis of hepatosplenic schistosomiasis: from man to monkey to mouse to molecule. | | 1979 | 120556 |
| schistosoma mansoni and schistosoma japonicum: comparison of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activities in adults. | glucose-6-phosphate dehydrogenase activity in paired adult schistosoma mansoni is about twice as great as in paired adult schistosoma japonicum. 2. 6-phosphogluconate dehydrogenase activity accounts for 25.8% of the measured production of reduced nicotinamide adenine dinucleotide phosphate (nadph) in s. japonicum but only 8.6% of the measured production of nadph in s. mansoni. 3. these data suggest a species difference in 6-phosphogluconate metabolism. | 1977 | 318249 |
| intestinal and blood parasites in the north lore district, central sulawesi, indonesia. | over 1,000 stool specimens from residents of the napu and besoa valleys, central sulawesi, indonesia were examined. schistosoma japonicum was detected in 31% of napu valley residents while in only 2% of the besoa valley residents. hookworm infections were the most frequently encountered helminth parasitisms in both valleys. other helminth parasites encountered were: ascaris lumbricoides, trichuris trichiura, enterobius vermicularis, strongyloides stercoralis, physaloptera sp., diphyllobothrium s ... | 1977 | 335530 |
| trends in the development of chemotherapy for parasitic diseases. | | 1978 | 364672 |
| human parasitoses of the malili area, south sulawesi (celebes) province, indonesia. | a biomedical survey was conducted in 9 villages in the malili area of south sulawesi, indonesia. blood specimens were examined for malaria and microfilariae; stool specimens were examined for intestinal parasites. malaria parasitemias were rare; plasmodium falciparum was detected in 10 and p. vivax in 11 of 985 blood smears. malayan filariasis was endemic to all villages surveyed. the overall prevalence of detectable microfilaremias was 15%, varying from 34% in kawata to 1% in nuha. microfilaria ... | 1978 | 364674 |
| potentiation of schistosome granuloma formation. by lentinan--a t-cell adjuvant. | lentinan is a fungal polysaccharide which acts as a t-cell adjuvant. when this glucan was administered to thymus-intact mice by intraperitoneal injection, conspicuously enlarged lung granulomas formed in response to either schistosoma mansoni or s japonicum eggs or to antigen-coated polyacrylamide beads. liver granulomas in cercaria-induced s mansoni infection were augmented up to eight-fold in volume. by contrast, nude mice showed a complete absence of hypersensitivity granulomas, regardless of ... | 1979 | 371408 |
| schistosoma japonicum: highly irradiated cercariae as a test for specific immunity in rhesus monkeys. | | 1977 | 408169 |
| north borneo (malaysia): a new locality for schistosoma japonicum. | eleven pairs of schistosomes, indistinguishable from the classical schistosoma japonicum, were found in a monkey (macaca fascicularis) taken near ranau in north borneo. the new locality is within the recorded range of the species which extends from japan, china, taiwan, and philippines through southeast asia to the celebes. | 1978 | 415627 |
| heterologous mating of schistosoma japonicum and schistosoma incognitum in experimentally infected rodents. | | 1979 | 483010 |
| experimental studies of schistosomal pigment from schistosoma japonicum. | the schistosomal and malarial pigments were distinguishable before and after extraction from the host liver. presence of iron in both pigments was ascertained by the elemental x-ray analysis. histochemically, however, schistosomal pigment was similar to that of malarial pigment. | 1979 | 374107 |
| [studies on the diagnosis of schistosomiasis japonica. (2) analysis of the efficiency of mifc method on the detection of schistosome eggs immersed into feces (author's transl)]. | | 1979 | 527924 |
| schistosomiasis japonica in barrio san antonio, basey, samar , the philippines. i. epidemiology and morbidity. | barrio san antonio is a coastal settlement on the san juanico straits in the municipality of basey on the island of samar, the philippines. it has a population of approximately 1,900 in 320 households. initially, 851 residents (45%) of 240 households participated in this survey to determine the prevalence and intensity of schistosoma japonicum infection, and morbidity as indicated by associated hepatomegaly and splenomegaly. as a result of an initial single stool examination of 1 ml by a modifie ... | 1979 | 315724 |
| fatty acid and lipid class composition of schistosoma japonicum eggs. | | 1977 | 299628 |
| [scanning and transmission electron microscopy of schistosoma japonicum egg shell (author's transl)]. | | 1979 | 263648 |
| [observations on the histopathological changes of schistosoma japonicum and host liver caused by pyquiton in experimental chemotherapy (author's transl)]. | | 1979 | 262815 |
| drug trial of schistosoma japonicum enfection in indonesia. | a limited drug trial was carried out on 42 cases with schistosomiasis japonica from an endemic area of central sulawesi. the drugs used were niridazole and stibophen. the effects of treatment were reported and discussed. the results of this study offer promise for treating s. japonicum infection in central sulawesi on a larger scale. | 1976 | 193201 |
| schistosoma mansoni and schistosoma japonicum: effects of infection on induction of tryptophan oxygenase in mouse livers. | | 1977 | 122552 |
| [a preliminary report on ocular symptoms in late stage of schistosomiasis japonica (author's transl)]. | | 1979 | 122338 |
| immunobiology of schistosomiasis. | although malaria and hookworm disease appear to be on the decline, another dreaded parasitic disease-schistosomiasis-is on the increase. presently, the number of infected individuals with schistosomes is estimated to be 250 million, and even though only a small proportion of them become sick and die, schistosomiasis remains a medical problem of great significance. the high incidence of infection of man with schistosoma mansoni, schistosoma japonicum or schistosoma haematobium, as well as the chr ... | 1979 | 118264 |
| clinical studies on cerebral schistosomiasis japonica in the philippines. | the author examined the cerebral schistosomiasis japonica (csj) in the philippines which is one of the areas heavily infected with s. japonicum. seventy-five subjects were selected randomly from 307 patients with csj, who showed neurological symptoms such as convulsions, paroxysmal disturbance of consciousness and hemiparesis. the mean age of the subjects was 33. of the 71 patients who had paroxysmal disease, 54 had convulsions, in 33 of which it was of the jacksonian type, and 24 had psychomoto ... | 1979 | 117911 |
| preliminary observations on immune function of schistosomiasis japonica patients. | | 1979 | 110546 |
| immunoglobulin e, mast cells, and eosinophils in the skin of rhesus monkeys immunized with x-irradiated cercariae of schistosoma japonicum. | immunoglobulin e (ige), mast cells, and eosinophils in the skin of rhesus monkeys immunized with highly x-irradiated cercariae of schistosoma japonicum were studied. ige was stained by the unlabeled antibody enzyme method and was found on mast cells. before challenge, mast cells were found only in the dermis. immediately after the challenge, mast cells were found in both the dermis and epidermis and many of them were degranulated. soon after, margination and emigration of granulocytes, predomina ... | 1979 | 109404 |
| [fundamental studies for the use of ria-gnost (peg) and its use for the measurement of serum aft content in patients with chronic schistosomiasis japonica (author's transl)]. | | 1978 | 81332 |
| effects of schistosoma mansoni and schistosoma japonicum infections on induction of hepatic tyrosine aminotransferase in mice. | | 1978 | 45516 |
| phosphodiesterase activity in adult schistosoma japonicum. | | 1977 | 22943 |
| pulmonary lesions in rabbits with experimental schistosomiasis japonica--derivation of schistosome eggs. | | 1979 | 502437 |
| schistosoma mekongi sp. n. from man and animals, compared with four geographic strains of schistosoma japonicum. | schistosoma mekongi sp. n. is described from man and animals in cambodia. it is compared to 4 geographic strains of schistosoma japonicum. it differs from s. japonicum in the size of embryonated eggs, in the length of the prepatent peroid in the mammalian host, and in its utilization of a different snail host. the relative usefulness of conventional morphologic criteria in the differentiation of asian schistosomes is discussed. | 1978 | 682060 |
| detection of antibodies in schistosoma japonicum infections by a micro-technique of enzyme-linked immunosorbent assay (elisa). | antibodies in schistosoma japonicum infections were successfully detected by micro-technique (0.3ml/well) of elisa on polystyrene microtiter plates using peroxidase labelled anti-human igg and 5-amino salicylic acid as conjugate and substrate, respectively. serum samples collected from 22 proven patients in leyte, philippines showed titers of higher than 1:960 in 18 cases, 1:240 in 2 cases and 1:120 in 2 cases whereas titers of 22 proven negative sera collected in tokyo were less than 1:15. thou ... | 1979 | 502084 |
| human schistosomiasis: postmortem experience at chulalongkorn hospital. | | 1979 | 501265 |
| longitudinal study on schistosoma japonicum infections in the philippines. incidence and prevalence among school children in dagami area, leyte. | the annual incidence of schistosoma japonicum infection was calculated from the record of the yearly examination among school children of dagami area, leyte, philippines. data were processed mainly by the computer. children were examined for eggs by the merthiolate formalin concentration technique and by the circumoval precipitin test (copt) once a year in 3 consecutive school years (sy), sy 1974/75, 1975/76 and 1976/77. about 600 to 700 children were examined yearly and the ratios of cases rech ... | 1979 | 480676 |
| schistosomiasis in oklahoma. | | 1979 | 479975 |
| [studies on the diagnosis of schistosomiasis japonica. (1) circumoval precipitin (cop) test as a method of screening of the subjects for fecal examination (author's transl)]. | examinations were performed on 351 individuals of shikishima village, yamanashi prefecture. three fecal samples were collected at one-week intervals and examined by mifc method without iodine. reactions with a diameter of 9 mm or more in wheal and/or 20 mm or more in erythema were regarded as the positive for the intradermal reaction using melcher's antigen (1 : 1,000). for the cop test, each one drop of serum and a saline suspension of eggs were mixed on a microscope slide and sealed a coversli ... | 1979 | 468099 |
| structure of the schistosome eggshell: amino acid analysis and incorporation of labelled amino acids. | preparations of eggshells of schistosoma mansoni and s. japonicum were hydrolyzed and analyzed for amino acid composition. both species showed great similarities in the proportions of each residue found. the predominant amino acid in shell hydrolysates was found to be glycine, which accounted for 37% of s. mansoni and 45% of s. japonicum amino acids. four components (glycine, aspartic acid, lysine, and serine) totalled 68--75% of amino acids in the eggshells. other individual amino acids were pr ... | 1979 | 453448 |
| the schistosoma japonicum egg granuloma. ii. cellular composition, granuloma size, and immunologic concomitants. | studies of granulomatous hypersensitivity to schistosoma japonicum eggs were performed at various time periods up to 20 wk after the induction of light infections in mice. cell populations which were determined in granulomas isolated from the livers revealed a maximum in the total number of cells at 6 wk with a decline of 36% by 20 wk. large mononuclear cells were predominant at all time periods, with eosinophils being the second most common cell. measurements of granuloma diameters around singl ... | 1978 | 417640 |
| a mammalian reservoir of schistosoma japonicum in the napu valley, central sulawesi, indonesia. | | 1978 | 739312 |
| preliminary clinical trials with praziquantel in schistosoma japonicum infections in the philippines. | praziquantel, a new antischistosomal compound, was tested for tolerance and efficacy against placebo in two double-blind clinical trials in philippine patients infected with schistosoma japonicum.the compound was given orally at a dose of 3 x 20 mg/kg at intervals of 4 hours to a total of 82 patients-some without advanced disease and some with hepatosplenic involvement. a total of 43 patients received placebo. in a single-blind trial, 42 patients were given a single oral dose of 50 mg/kg. monito ... | 1979 | 396056 |
| double-blind studies of tolerance to praziquantel in japanese patients with schistosoma japonicum infections. | the first clinical trials of praziquantel against schistosoma japonicum infections in japan were planned to assess tolerance only. three double-blind studies against placebo involving a total of 51 patients were conducted with dosages of praziquantel of 1 x 20 mg/kg body weight, 2 x 20 mg/kg, 3 x 20 mg/kg given on one day.the frequency of unwanted side effects was higher in the group of patients given praziquantel at a dose of 3 x 20 mg/kg than in all other drug- or placebo-treated patients. in ... | 1979 | 396055 |
| prevalence of schistosome infections within molluscan populations: observed patterns and theoretical predictions. | the paper draws together a large and scattered body of empirical evidence concerning the prevalence of snail infection with schistosome parasites in field situations, the duration of the latent period of infection in snails (and its dependence on temperature), and the mortality rates of infected and uninfected snails in field and laboratory conditions. a review and synthesis of quantitative data on the population biology of schistosome infections within the molluscan host is attempted and observ ... | 1979 | 542322 |
| prevention of the mutagenic activation of an antischistosomal isothiocyanate in primates by an antibiotic. | administration of 4 nitro-4' isothiocyano-diphenylamine (cgp 4540, amoscanate) to two nonhuman primates, macaca mulatta and cebus apella, resulted in the appearance of mutagenic material in the urines of these animals. mutagenic metabolites of this drug could also be detected in the urines when the drug was administered to primates infected with schistosoma mansoni and schistosoma japonicum. as observed previously in mice, the mutagenic activation of amoscanate can be prevented in primates by co ... | 1979 | 553807 |
| study of the circumoval precipitate in schistosomiasis japonica by immunofluorescent technic. | the 48-hour circumoval precipitates formed by infected human and rabbit sera on lyophilized schistosoma japonicum eggs were stained with the corresponding fluorescein-labelled monospecific goat antisera for study under a fluorescent microscope. the three major ig classes were found to participate in the formation of the precipitate, with major components being igg and igm; iga participated least. ige and c3 also contributed to the precipitate. the circumoval precipitate on s. japonicum eggs is t ... | 1976 | 769580 |
| [diagnosis of schistosomiasis japonica by dry ova precipitation reaction (author's transl)]. | | 1979 | 555915 |
| conversion of schistosome cercariae to schistosomula in serum-supplemented media, and subsequent culture in vitro. | both schistosoma japonicum and s. mansoni cercariae, axenized by washing in nctc 109, transformed to schistosomula when incubated directed in nctc 109 containing 2--50% human or 50% rabbit serum at 37 degrees c. the resultant schistosomula were grown in vitro to adults which mated, although the females did not produce eggs. the cercaria-schistosomulum transformation took place at a slower rate in heat inactivated serum than in unheated serum. | 1978 | 566806 |
| mechanism of immunity of schistosomiasis: histopathologic study of lesions elicited in rhesus monkeys during immunizations and challenge with cercariae of schistosoma japonicum. | | 1975 | 811795 |
| schistosoma japonicum-like egg from a human from central kalimantan, indonesia. | | 1978 | 568315 |
| schistosome antigens in the circulation of chimpanzees infected with schistosoma japonicum. | chimpanzees infected with schistosoma japonicum develop circulating schistosome antigens in their circulation between 6 and 9 weeks post-exposure. the minimum number of circulating antigens ranges from one to three. these antigens also cross-react with an antiserum against s. mansoni adult worms. clearance of these antigens from the circulation several weeks later typically occurs. persistence of these antigens could result in the observed renal damage. | 1976 | 820210 |
| schistosomiasis japonica in barrio san antonia, basey samar, in the philippines: iii. the plasma circumoval precipitin test-procedure and use in epidemiologic studies. | a plasma circumoval precipitin test is proposed as the basic diagnostic tool for epidemiologic studies on schistosomiasis japonica in the philippines. the collection of plasma, the preparation of the cop test slide, and the reading and interpretation of results are described in detail with pertinent comments. the cost, advantages and usefulness of the test are also discussed. | 1979 | 573501 |
| schistosoma japonicum-like ova in liver and rectal biopsies of three cases in sabah, malaysia. | three cases of schistosomiasis in 2 filipinos and one chinese in sabah are reported. diagnosis was based on incidental histological findings of schistosoma japonicum-like ova in the liver and rectal biopsies. as these 3 patients are immigrants to sabah, it is assumed that they are imported cases, and that sabah has been free of the disease from 1970 to 1977. | 1979 | 573502 |
| schistosoma japonicum: semiquantitative assessment of circulating immune complexes, serum c1q and c3, and their relationship to renal pathology and hepatic fibrosis in rabbits. | | 1977 | 862707 |
| oncomelania hupensis quadrasi from mindoro (victoria), leyte (palo), and mindanao (davao del norte) of the philippines: susceptibility to infection with philippine isolates of schistosoma japonicum. | | 1977 | 592045 |
| tricarboxylic acid cycle enzyme activities in adult schistosoma mansoni and schistosoma japonicum. | reduced tricarboxylic acid cycle enzyme activities were found in paired adult schistosoma mansoni and s. japonicum in comparison to those reported for s. mansoni cercariae (coles, 1973). succinate dehydrogenase activity, which has not been previously reported for either adult blood fluke, is more than twice as great in paired adult s. japonicum as in paired adult s. mansoni, but the activity is low in both species of adult worms. the similar low levels of tricarboxylic acid cycle enzyme activiti ... | 1977 | 595083 |
| comparative studies on reading criteria of circumoval precipitin reaction of schistosoma japonicum for field survey in highly endemic area. | | 1977 | 599717 |
| prolonged latent schistosomiasis. | | 1978 | 691174 |
| current status of schistosomiasis japonica in sorsogon province, republic of the philippines. | a resurvey of irosin and the eight municipalities surrounding it for schistosomiasis japonica using copt and fect was done in order to determine the status of the disease thirty years after it was first reported in the town of irosin in 1947. in irosin, the results by fect showed that there was a decrease in prevalence from 5.7% to 2.8%, however, if by copt, then there was an increase from 5.7% to 12.2%. there is a definite trend of the disease to spread from irosin into the surrounding municipa ... | 1978 | 705421 |
| schistosoma japonicum-type infection in malaysia--report of the first living case. | the first living patient with a schistosoma japonicum-type infection who presented with the nephrotic syndrome is reported in detail. it is not clear whether the nephrotic syndrome was due to the schistosome infection or to the deposition of hepatitis b antigen and antibody complexes. this is the tenth case of schistosomiasis reported from aborigines in malaysia and a sylvatic source of infection is suggested. | 1978 | 705845 |
| in vitro cultivation of schistosoma japonicum. | | 1976 | 1025035 |
| a benzodiazepine derivative and praziquantel: effects on musculature of schistosoma mansoni and schistosoma japonicum. | the benzodiazepine derivative (ro 11-3128) which has central nervous effects similar to other benzodiazepines, and praziquantel (pz), are two new antischistosomal drugs. at low concentrations these drugs will produce a marked spastic paralysis of male schistosoma mansoni musculature. an analysis of the action of these drugs on the parasite's musculature shows that ro 11-3128 and pz produced a rapid rise in the tension of the musculature of male schistosomes. various compounds known to interact w ... | 1978 | 714190 |
| [relationship between chronic schistosomiasis japonica and carcinoma in the large intestine.--studies on 12 cases of adenocarcinoma of large intestine associated with eggs of schistosoma japonicum (author's transl)]. | | 1978 | 716804 |
| the maintenance of philippine and other strains of schistosoma japonicum in the laboratory and the differences among philippine strains of oncomelania. | | 1976 | 1025723 |
| [clinical study of cerebral schistosomiasis japonica in leyte (philippines)--follow up study 2 years after treatment with antischistosomal agents (author's transl)]. | | 1978 | 718744 |
| immunopathologic mechanisms in parasitic infection with emphasis on schistosomiasis. | | 1978 | 725651 |
| effects of stressful conditions on the development and movement of reproductive cells in schistosoma japonicum. | adult s. japonicum exposed to 3h-thymidine to label reproductive cells were cultured in vitro, maintained intraperitoneally, or transplanted as unisexual infections to hamsters. daily samples were taken, processed for autoradiography, and observed for abnormal morphological and developmental characteristics. by day 5 of in vitro culture in medium 199 and calf serum, all worms were dead. the vitelline system was the most sensitive to culture conditions and labeled vitelline cells never moved from ... | 1978 | 739319 |
| final localization of schistosoma japonicum in the lungs of field rats, rattus mindanensis, in leyte, philippines. | among 45 specimens of rattus mindanensis (hearns, 1,905) caught in an endemic area of schistosomiasis japonica in leyte, philippines, 39 (86%) were found to be positive for schistosoma japonicum. lung examination of 24 autopsied rats revealed a high incidence of pulmonary infection and the flukes were found in 20 rats (83%). in 24 (73%) out of 33 rats, the flukes were seen in the hepatic portal vein. only 29% of the rats were positive for schistosoma ova in the intestinal wall. the average numbe ... | 1978 | 750677 |
| cross reactivity of schistosome antigens between schistosoma mansoni and japonicum. | fifty six patients with chronic schistosomiasis japonica were given skin tests with preparations made of schistosoma mansoni and schistosoma japonicum. there was a high, significant positive correlation between the results of both antigens. among 47 serum samples tested with indirect hemagglutination (iha) 27 had the antibody titer 1:16 or higher, which was diagnostically significant in combination with positive skin test results. the results indicate a definite cross reactivity of japonicum and ... | 1979 | 760262 |
| mouse antibody-dependent eosinophil and macrophage adherence and damage to schistosomula of schistosoma mansoni. | the effects of sera from s. mansoni-infected mice together with eosinophil- and macrophage-rich peritoneal exudate cells (pec) on the schistosomula were examined in vitro. adherence to and killing of the parasite by pec is mediated through a complement-independent opsonizing igg. destruction of schistosomula was assessed morphologically and by evaluating their infectivity to normal mice. by using ferritin-labeled anti-mouse immunoglobulin, the antibody was localized on the surface of the schisto ... | 1979 | 762428 |
| serology of capillaria philippinensis infection: reactivity of human sera to antigens prepared from capillaria obsignata and other helminths. | the reactivity of sera from 151 confirmed human cases of capillaria philippinensis infection was examined by double diffusion and indirect hemagglutination (iha) tests chiefly against capillaria obsignata antigen because of the present unavailability of c. philippinensis antigen. antigens from additional parasites and other human and animal sera representing a variety of helminthic infections were used for comparison. of 71 pre-treatment human sera, 56.3% were reactive by double diffusion test a ... | 1975 | 804269 |
| recovery of schistosomula in the skin of rhesus monkeys immunized with cercariae of schistosoma japonicum exposed to high dose of x-irradiation. | | 1975 | 811784 |
| malic dehydrogenase patterns in different strains of schistosoma japonicum and subspecies of oncomelania hupensis. | malic dehydrogenase (mdh) of the formosan philippine and indonesian strains of schistosoma japonicum and 3 subspecies of snails, oncomelania hupensis formosana, o. h. quadrasi, and o. h. lindoensis were identified by disc electrophoresis with 10.5% acrylamide gel columns using tris-malic buffer. male worm extracts of s. japonicum demonstrated 3, 2, and 2 clear mdh patterns and female worm extracts showed patterns of 2, 1 and 1 for the formosan, philippine and indonesian strains of the parasite, ... | 1976 | 1037537 |
| schistosoma japonicum: immunopathology of nephritis in macaca fascicularis. | | 1975 | 812719 |
| comparative effects of hycanthone in schistosoma mansoni and schistosoma japonicum. | after in vitro hycanthone treatment followed by a 20-hour incubation in drug-free medium, schistosoma mansoni were still resistant to labeling by a fluorescent analog of acetylcholine. s. japonicum, in contrast with the hycanthone sensitive species, showed prompt reversal of the blocking effects of hycanthone on fluorescent labeling. this finding suggests that differences in the reversibility of hycanthone may correlate with the usefulness of the drug in the therapy of schistosome infections by ... | 1977 | 848646 |
| experimental schistosoma japonicum infection in miniature pigs. | | 1977 | 859095 |
| distribution of oncomelania hupensis in the napu valley of central sulawesi, indonesia. | fifteen colonies of oncomelania hupensis were found near trails transecting the north lore district, napu valley, central sulawesi. habitats were in abandoned rice fields, uncultivated grazing areas for livestock, roadside ditches and, in one case, an actively worked rice field. marsh grasses, ischaemum barbatum and laersia hexandra, were the most common plants in oncomelanid habitats. other mollusks found in association with o. hupensis were radix sp., melanoides sp., gyraulus sp., idiopoma sp. ... | 1975 | 1166348 |
| scanning electron microscope observations on adult schistosoma japonicum. | the integumental surfaces of critical point dried adult schistosoma japonicum were studied by scanning electron microscopy. there are no bosses or spines on the dorsal surface of the male, which is ridged and presents a spongy appearance. many spines cover the inner surface of the oral sucker and extend to the pharyngeal opening. the oral sucker shows a rim with spines of variable size and sharpness inward and outward from the rim. the ventral sucker possesses many spines which are smaller than ... | 1977 | 864556 |
| rejection of mouse-derived schistosoma japonicum and serum lethality of host immunized with mouse globulin or mouse erythrocytes. | fourteen-day-old, mouse-derived schistosoma japonicum schistosomula survived, matured, and deposited viable eggs following surgical transfer to the hepatic portal system of rabbits. the survival of such schistosomula is essentially eliminated in rabbits immunized with either mouse erythrocytes or mouse gamma globulin. sera from rabbits immunized with either mouse erthrocytes or mouse gamma globulin in the presence of normal leukocytes is lethal for mouse-derived schistosomula 14 days of age or o ... | 1977 | 915611 |
| intestinal and blood parasites in the banggai kabupaten, central sulawesi, indonesia. | a survey for blood and intestinal parasites was carried out in the banggai kabupaten central sulawesi, indonesia. a total of 336, stool specimens were obtained from 182 males and 154 females ranging in age from 2 to 90 years. hookworm, trichuris trichiura and ascaris lumbricoides were the most common helminths encountered. schistosoma japonicum was noticeably absent in the population sampled. the following intestingl protozoa were detected: entamoeba coli, e.histolytica, iodamoeba bütschlii, gia ... | 1977 | 607427 |
| evaluation of a technique of circumoval precipitin test using blood taken on filter paper and a microtiter technique of complement fixation test of schistosoma japonicum. | for the circumoval precipitin test (copt) blood was taken on quantitative blood sampling filter paper by finger prick from outpatients at the schistosomiasis control pilot project, palo, leyte, philippines. the volume of serum available per strip of filter paper was 0.04 ml and this was extracted at 1:3, 1:5 and 1:8 dilutions. lyophilized eggs of schistosoma japonicum were mixed with the diluted serum on a microscope glass slide and incubated at 37 degrees c for 2 days. the reaction was read fol ... | 1975 | 1228231 |
| biomedical survey in north samar province, philippine islands. | a biomedical survey was carried out in north samar province, philipines to update information on the prevalence of parasitic and other infectious diseases. a total of 1,394 stool specimens, 1,859 blood smears and 1,274 sera were collected from persons living in 8 barrios. stools were examined for intestinal parasites, bloods smears for malaria and filariasis and sera tested for antibodies to schistosoma japonicum, entamoeba histolytica, toxoplasma gondii, influenza a and b, and japanese encephal ... | 1977 | 614707 |
| scanning electron microscope observations on miracidium, cercaria, and cercarial papillar patterns of schistosoma japonicum. | the surfaces of schistosoma japonicum miracidia and cercariae were examined with the scanning electron microscope, and argentophilic papillae of s. japonicum cercariae, presumed to be sensory, with both the scanning electron microscope and the light microscope. miracidia are covered with cilia, and the apical papilla is covered with cytoplasmic folds that form an anastomosing network. there is an excretory pore on the posterior one-third of the body. the tegument of s. japonicum cercariae is cov ... | 1978 | 627977 |
| t and b cell epitope mapping of sm23, an integral membrane protein of schistosoma mansoni. | sm23 is an integral membrane protein of the blood-vessel dwelling parasitic worm schistosoma mansoni. this protein has been detected with antibodies in all stages of the parasite found in the human host, notably the lung stage, and therefore is of interest as a vaccine candidate. in addition sm23 has been shown to be a member of a proposed new superfamily of membrane proteins whose structures do not conform to the previously known classifications. to date there are 13 members including me491 (cd ... | 1992 | 1281197 |
| observations on the surface of different strains of adult schistosoma japonicum. | | 1978 | 641684 |
| counterimmunoelectrophoresis in the detection of antibodies to schistosoma japonicum. | counterimmunoelectrophoresis (cie) was used to detect antibodies to schistosoma japonicum soluble egg antigen in 118 sera from people living in a schistosomiasis endemic area in the philippines. the sera were also tested for antibodies by the circumoval precipitin test (copt); 53% were found positive by cie and 48% positive by copt. no significant differences were found between the tests (p = 0.18 by mcnemar's test). cross-reactions with sera from patients with intestinal capillariasis and monke ... | 1978 | 646020 |
| anti-liver antibody in rabbits infected with schistosoma japonicum. | anti-liver antibody has been demonstrated in the sera of schistosoma japonicum-infected rabbits. by the 8th week after exposure to cercariae, perceptible levels of autoantibody were present and appeared to be direct predominantly determinants located in the cell membrane of the hepatocyte. | 1976 | 961981 |
| [comparative study on antigenicity and immunogenicity of the 24-26 kda antigen and the recombinant sj26 antigen of schistosoma japonicum]. | this paper reports on the comparison of the recombinant sj26 (rsj26) antigen originated from the philippine strain and 24-26 kda antigen isolated and purified from chinese mainland strain of s. japonicum for their antigenicity and immunogenicity. the results showed that there were obvious cross reactions between rsj26 and 24-26 kda antigen when rsj26 antigen was tested against specific antibodies in sera from mice infected with the mainland strain of s. japonicum or 24-26 kda antigen was tested ... | 1992 | 1307273 |
| studies on morphological characteristics of japanese strain of schistosoma japonicum in rabbits. | the present investigation was undertaken to determine some morphological characteristics of japanese strain of schistosoma japonicum, the results are summarized as follows: (1) the pattern of testes in male worms can be divided into two types: the tandem (37.6%) and non-tandem (62.4%). (2) the number of testes varied from 1 to 13. the percentage of specimens with 7 testes was much higher than of others with both in tandem (70% against 30%) and non-tandem (86% against 14%) arrangement. (3) the un ... | 1976 | 977230 |
| purification and characterization of the mouse mammary tumor virus protease expressed in escherichia coli. | the mouse mammary tumor virus (mmtv) protease gene was cloned into pgex-2t, an escherichia coli expression vector containing the glutathione s-transferase coding region of schistosoma japonicum. the chimeric protein was formed by fusion of the glutathione s-transferase with a hexapeptide which contains a thrombin cleavage site, followed by the mmtv protease. affinity chromatography on a glutathione-sepharose 4b column was used to isolate the chimeric protein. after thrombin cleavage, the glutath ... | 1992 | 1331110 |
| diagnosis of schistosoma japonicum infections in man: an introduction and brief review. | | 1976 | 1025719 |
| culture of schistosoma japonicum (philippine strain) from the cercarial stage and the effects of immune rabbit and human sera in vitro: a preliminary report. | | 1976 | 1025721 |
| a clinico-pathologic study of cases with schistosoma japonicum infection in indonesia. | combined clinico-pathological and laboratory examinations were carried out on 52 s. japonicum infected patients from an endemic area in central sulawesi, indonesia. all of these patients exhibited signs and symptoms of chronic hepato-splenic schistosomiasis. none of the patients showed evidence of liver cirrhosis on histopathological examination. however, varying degrees of portal fibrosis were exhibited. the correlation between the degree of fibrosis and the clinical and laboratory findings wer ... | 1976 | 1025729 |
| ambilhar in the treatment of schistosoma japonicum infection and as an egg suppressant for mass treatment. | ambilhar or niridazole at a dose of 25 mg per kg body weight for 7 days was found ineffective against sl japonicum infection. longer period of treatment for 10 to 14 days gave impressive stool negative conversion and egg reduction rates but with moderately severe reactions, the most alarming of which was hallucination. to minimize toxicity, the daily dose was reduced but given for a longer duration so that the total amount of the drug given per kilogram body weight was approximately the same as ... | 1976 | 1025735 |
| recommendations for future research work on the control of schistosoma japonicum in east and southeast asia. | | 1976 | 1025736 |
| preliminary observations on the biology of the indonesian strain of schistosoma japonicum: animals and oncomelanid snails. | laboratory animals and subspecies of oncomelania hupensis were exposed to experimental infections with a strain of schistosoma japonicum from the lindu valley, central sulawesi, indonesia. all laboratory animals given 50 cercariae were suspecptible to infection with the greatest number of worms being found in mice followed by wistar rats, long evans rats, mongolian gerbils, wild rats, hamsters and guinea pigs. rabbits and the taiwan monkeys given larger numbers of cercariae were also susceptible ... | 1976 | 1030835 |
| liver ultrasound findings in a low prevalence area of s. japonicum in china: comparison with history, physical examination, parasitological and serological results. | the paper describes a study carried out in a community in dongdian township, anhui province, people's republic of china. medical history and the results of a physical examination, ultrasound investigation, parasitological and serological tests for schistosoma japonicum infection were compared in 661 persons of 169 households. a lack of correlation between parasitological and serological indicators of infection and morbidity was observed in this area of low (6.4%) prevalence and intensity of infe ... | 1992 | 1351356 |
| antischistosomal activities of sesquiterpene lactones and steroid glucosides from vernonia amygdalina, possibly used by wild chimpanzees against parasite-related diseases. | | 1992 | 1368347 |
| control of schistosoma japonicum infection in lindu valley, central sulawesi, indonesia. | in indonesia, schistosomiasis is presently confined to two endemic areas in central sulawesi; lindu (1,500) and napu (5,000 inhabitants) valleys. because of various development schemes now underway, it is feared that the natural balance which existed for many years between the parasite, the snail intermediate hosts and man, will be upset and will place some 70,000 people of the adjoining palu and palolo areas at risk. measures are being taken to control and prevent the spread of the disease. a p ... | 1976 | 1030837 |