| a conserved secondary structure for telomerase rna. | the rna moiety of the ribonucleoprotein enzyme telomerase contains the template for telomeric dna synthesis. we present a secondary structure model for telomerase rna, derived by a phylogenetic comparative analysis of telomerase rnas from seven tetrahymenine ciliates. the telomerase rna genes from tetrahymena malaccensis, t. pyriformis, t. hyperangularis, t. pigmentosa, t. hegewishii, and glaucoma chattoni were cloned, sequenced, and compared with the previously cloned rna gene from t. thermophi ... | 1991 | 1840508 |
| extensive changes in the locations and sequence content of developmentally deleted dna between tetrahymena thermophila and its closest relative, t. malaccensis. | tetrahymena thermophila has two different types of nuclei in a single cell. the development of the transcriptionally active macronucleus from a transcriptionally inert micronucleus is accompanied by the elimination of numerous dna segments, called deletion elements or internally eliminated sequences (iess). to try to distinguish between alternative modes for the generation of iess during evolution, dna sequences at three loci that contain iess in t. thermophila were examined in tetrahymena malac ... | 2007 | 17300523 |
| telomeric repeats of tetrahymena malaccensis mitochondrial dna: a multimodal distribution that fluctuates erratically during growth. | the linear mitochondrial dna (mtdna) of tetrahymena malaccensis has tandem 52-base-pair repeats at its telomeres. the mtdna has a multimodal distribution of telomeres. different groups in the distribution have different numbers of telomeric repeats. the standard deviation of the size of each end group is independent of the mean size of the end group. the two sides of the mtdna have different multimodal distributions of repeats. cloned cell lines have multimodal distributions of mtdna telomeres d ... | 1988 | 3185556 |