| babesia rodhaini: immuno-induction of antigenic variation. | | 1975 | 53214 |
| babesia rodhaini, babesia bovis, and babesia bigemina: analysis and sorting of red cells from infected mouse or calf blood by flow fluorimetry using 33258 hoechst. | | 1979 | 92419 |
| pathogenesis of acute avian malaria. iii. antigen and antibody complexes as a mediator of anemia in acute plasmodium gallinaceum infections of chickens. | in a study of antigens and antibodies found in malarious chicken blood, antigen activity was found in plasma, and in hypertonic saline eluates of blood cells. a soluble antigen was extracted from parasites liberated from erythrocytes. two classes of antigen were differentiated, one a globulin associated "serum antigen" which was found to show identity with a serum antigen from blood of rats with acute babesia rodhaini infection, and another that was associated with the plasmodium gallinaceum par ... | 1975 | 125550 |
| studies on cell fusion between babesia rodhaini-infected mouse erythrocytes and baby hamster kidney cells. | | 1975 | 166951 |
| studies on immune responses to parasite antigens in mice. v. different susceptibilities of hypothymic and intact mice to babesia rodhaini. | hypothymic balb/c.nu/nu mice are more resistant than intact balb/c.nu/+ mice to babesia rodhaini and a proportion survive a dose of infected blood which is uniformly lethal to nu/+ mice. this proportion of nu/nu survivors is not affected by administration of an anti-babesial drug, whereas the majority of nu/ + mice develop a long-lasting resistance to infection. the data suggest that t cell dependent activities are involved both in the acceleration of parasitaemia and in the development of drug- ... | 1977 | 300714 |
| protection of mice against plasmodium and babesia infections: attempts to raise host-protective sera. | in an attempt to generate large numbers of mice resistant to plasmodium berghei and babesia rodhaini to be used as donors of antibody-secreting cells for hybridoma production, various methods of inducing resistance to repeated challenge with infected blood cells have been explored. although results of independent experiments varied markedly, prior injection of cba/m mice with bcg, and prior infection of balb/c mice with plasmodium yoelii, were found to be manipulations capable of inducing resist ... | 1978 | 375903 |
| resistance to babesia spp. and plasmodium sp. in mice pretreated with an extract of coxiella burnetii. | mice injected intravenously with a commercially available extract of coxiella burnetii prepared for use as the antigen in the complement fixation diagnostic test for q fever were subsequently resistant to infection with babesia microti, babesia rodhaini, and plasmodium vinckei petteri. the parasites appeared to die inside circulating erythrocytes. protection was unaffected by exposing the pretreated mice to 900 rads on the day before they were infected. to explain these findings, it is postulate ... | 1979 | 378850 |
| biochemistry of intraerythrocytic parasites. i. identification of enzymes of parasite origin by starch-gel electrophoresis. | enzymes of parasite origin were identified by starch-gel electrophoresis. the species of parasite studied were plasmodium berghei, plasmodium yoelii nigeriensis, babesia rodhaini and anthemosoma garnhami. lactate dehydrogenase, glucose phosphate isomerase and (nadp) glutamate dehydrogenase were detected in all species; phosphogluconate dehydrogenase was detected in both plasmodium species but malate dehydrogenase only in p. y. nigeriensis. glucose-6-phosphate dehydrogenase, alanine aminotransfer ... | 1979 | 386967 |
| biochemistry of intraerythrocytic parasites. ii. comparative studies in carbohydrate metabolism. | comparative studies were carried out on the glucose catabolism of mouse erythrocytes infected with plasmodium berghei, plasmodium yoelii, babesia rodhaini, babesia microti and anthemosoma garnhami, as well as on uninfected erythrocytes and reticulocytes. the results showed that there was little qualitative difference between the glucose utilization and lactate production of the parasites although quantitative differences between malaria parasites and piroplasms were observed. the rate of glucose ... | 1979 | 386968 |
| [studies on immunogenic properties of somatic and metabolic antigens of babesia rodhaini]. | | 1979 | 473980 |
| antibody to fibrinogen/fibrin products (anti-f) in malaria, babesiosis, and trypanosomiasis of rodents. | antibody to fibrinogen/fibrin related products (anti-f) was stimulated during the course of plasmodium chabaudi, babesia rodhaini, and trypanosoma lewisi infections in rats. titers of this autoantibody remained elevated in serum from rats that had recovered from each of the infections. column chromatographic studies indicated that anti-f was a 19s globulin, possibly igm. during acute infections high titers of anti-f were associated with elevated titers of cold-active hemagglutinin (cah) and immu ... | 1979 | 480072 |
| the effect of chronic protozoan infection by babesia rodhaini on leukemogenesis in mice. | the effect of chronic infection with the protozoan parasite babesia rodhaini on the subsequent development of mouse leukemia was investigated in three different murine leukemia-lymphoma model systems: congenital lymphoma (in akr mice), irradiation-induced lymphoma (in c57bl mice), and rauscher-virus-induced leukemia in nmri mice. leukemia incidence was significantly greater than in controls in babesia-infected (nmri strain) mice that had been infected with an adjusted dose of rauscher leukemia v ... | 1977 | 591132 |
| [the suitability of the enzyme-linked immunosorbent assay (elisa) for the demonstration of babesia antibodies in hyperimmune serums with the use of ectoantigens]. | from sera of highly parasitised mice and dogs with babesia rodhaini, b. galagolata and b. canis ectoantigens were isolated by column-chromatography and tested in the elisa for their serological properties. hyperimmunsera against the three babesia species were prepared in rabbits, mice and dogs. serologic cross-reactions occurred between the investigated babesia species although distinct titer differences could be observed between b. canis on one hand and b. rodhaini and b. galagolata on the othe ... | 1978 | 623620 |
| differential centrifugation and infectivity of babesia rodhaini freed by contiuous-flow ultrasonication. | | 1978 | 660389 |
| babesia rodhaini: passive protection of mice with immune serum. | immune serum delayed the onset of parasitemia in both intact and splenectomized mice, but it neither prevented the development of babesia rodhaini infection nor protected the mice from death even with further supplementation of immune serum during the infection. the protective antibodies in the serum are more effective in their action on free b. rodhaini parasites than on infected erythrocytes; the parasites (free or inside the red cells) being direct targets for the antibodies. passive administ ... | 1978 | 726044 |
| babesia rodhaini: requirement of complement for penetration of human erythrocytes. | a system has been developed in vitro in which human red cells, in the presence of fresh human (or rat) serum, are parasitized by the hemosporidian protozoan babesia rodhaini. the ability of b. rodhaini to penetrate red cells depends on factors of the alternative complement pathway (properdin and factor b) as well as ionic magnesium and the third (c3) and the fifth (c5) components of complement. these data indicate a novel mechanism by which a parasite is able to utilize the complement system. th ... | 1977 | 841340 |
| interaction of rate of latent heat removal during freezing and rates of subsequent cooling and warming on survival of the blood protozoan, babesia rodhaini. | | 1977 | 891237 |
| survival of aegyptianella pullorum, anaplasma marginale and various parasitic protozoa following prolonged storage in liquid nitrogen. | various protozoa species were examined using in vivo and in vitro methods to determine their ability to survive prolonged periods of storage in liquid nitrogen. the following protozoan species were successfully recovered after they had been cryopreserved for a period over 10 years: trypanosoma lewisi, t. cruzi, t. congolense, t. brucei, t. rhodesiense, t. gambiense, t. evansi, t. equinum, t. equiperdum, leishmania donovani, plasmodium berghei, p. praecox (relictum), babesia rodhaini and b. canis ... | 1977 | 919686 |
| the complement profile in babesiosis. | rats have been infected with babesia rodhaini, a protozoan agent that induces immune complex disease. assays for complement have revealed depletion of c2, c3, c4, c5, and whole complement in the course of infection. no evidence of depletion in the alternative (properdin) pathway was found. these findings are consistent with the conclusion that the classical complement pathway is activated during the course of the protozoan infection. | 1976 | 956661 |
| bioassay to measure effects of cooling and warming rates and protection by dimethyl sulphoxide on survival of frozen babesia rodhaini. | | 1976 | 991614 |
| babesia sp.: the relationship of stage of development to structure of intra- and extracellular parasites. | the relationship of stage of development to structure in babesia rodhaini and b. microti was studied by freeze-etching, carbon replication, and thin sectioning. the trophozoites of these babesia are surrounded by a single membrane over most of their surfaces, but in some regions of the cytoplasm, membranous structures may parallel the plasmalemma, providing a double membrane. merozoites are produced from trophozoites by budding. an early external indication that a bud will form is the organizati ... | 1975 | 1145729 |
| babesia rodhaini: a study of the effects of immune serum. | | 1975 | 1201890 |
| changes in c3 metabolism during protozoan infection (babesia rodhaini) in rats. | metabolism of the third component of complement (c3) and igg was measured in rats before and during infection with the hemosporidium agent babesia rodhaina. in the course of infection, hypocomplementemia and immune complex nephritis developed. during babesial infection, in most animals the half-life of c3 fell sharply, as did serum levels of c3; the catabolic rate for c3 sharply increased, whereas the synthetic rate sharply decreased. in contrast, the catabolic rate for igg remained unchanged. t ... | 1976 | 1270796 |
| babesia bovis, babesia bigemina, babesia canis, babesia microti and babesia rodhaini: comparison of ribosomal rna gene organization. | the three ribosomal dna (rdna) units have been cloned from an australian isolate of babesia bigemina. the organization of the units is very similar to that reported for a mexican isolate of b. bigemina. in babesia canis four rdna units have been identified. both babesia rodhaini and babesia microti contain two different rdna units. a small number of different rdna units appears to be a common feature of this group of protozoa. restriction enzyme analysis of the rdna units form these species and ... | 1992 | 1428519 |
| changes of splenic lymphocyte subpopulation in mice inoculated with babesia microti and babesia rodhaini. | changes of splenic lymphocyte subpopulation after babesia microti and babesia rodhaini inoculation in mice were examined by flow cytometric analysis. the b. microti inoculated mice showed a longer period of time from inoculation to the onset of increase or decrease parasitaemia (%), packed cell volume, total spleen cell numbers and surface immunoglobulin positive splenic cell numbers than respective periods in b. rodhaini inoculated mice. the thy-1 positive cell numbers in b. microti inoculated ... | 1992 | 1477155 |
| ribosomal dna sequence comparison of babesia and theileria. | previous studies on the taxonomy of babesia spp. (phylum apicomplexa) using morphological and life cycle characteristics have resulted in their classification into 3 subgenera, with the genus theileria being most closely related to them. using a strategy based on the direct sequence analysis of products derived by asymmetric pcr to determine the nucleotide sequences, we have tested the validity of this classification by sequencing the small subunit ribosomal rna genes amplified from 2 babesia sp ... | 1992 | 1518535 |
| immunological changes in babesia rodhaini infected balb/c mice after treated with anti-babesial drug; diminazene diaceturate. | a model system capable of investigating immunological changes was first established in babesia rodhaini infected mice with an aid of a drug, diminazene diaceturate (dd). intraperitoneal (ip) inoculation with b. rodhaini resulted in acute death in euthymic (nu/+) and athymic (nu/nu) balb/c mice. treatment with dd at an early stage of infection saved both mice from acute death. parasitemia recurred in some of them but resulted in death only in nu/nu mice. a re-challenge with 10(5) parasitized eryt ... | 1991 | 1832024 |
| the effect of immune serum and complement on the in vitro phagocytosis of babesia rodhaini. | the effect of immune serum and complement on the in vitro phagocytosis of babesia rodhaini was investigated. infected erythrocytes and parasites released from erythrocytes by lysis were phagocytosed by mouse peritoneal macrophages in vitro when the infected erythrocytes or parasites were exposed to hyperimmune b. rodhaini serum. complement, in the presence of immune serum, did not reproducibly enhance phagocytosis of infected erythrocytes or parasites alone. when adjusted for its effect on norma ... | 1991 | 1956695 |
| in vitro adherence of erythrocytes infected with babesia bigemina and babesia rodhaini to thrombospondin. | the adherence of erythrocytes infected with babesia bigemina and babesia rodhaini to thrombospondin (tsp) in vitro is demonstrated. blood with a range of parasitaemias was used and counts of cells which bound to tsp on plastic were significantly different from the controls with both babesia species. these studies indicated that tsp receptors are present on the surface of red blood cells infected with the two babesia species, although these parasites do not alter the membranes of infected erythro ... | 1990 | 2276864 |
| an antigenic determinant common to both mouse red blood cells and several membrane proteins of the parasitic protozoa babesia rodhaini. | four membrane proteins of babesia rodhaini have been identified by monoclonal antibodies. these proteins are differentiated by serological criteria and by tryptic peptide maps but contain common antigenic determinants. in vitro translation of parasite polyadenylated rna followed by immunoprecipitation demonstrates that these common determinants are located within the primary sequence of the protein and do not result from post-translational modification. part of the common amino acid sequence of ... | 1986 | 2426589 |
| studies on route of immunization with a mixture of killed parasites and adjuvants against babesia rodhaini infection in mice. | a series of experiments were undertaken to determine the most effective route of immunization with a mixture of killed babesia rodhaini antigen (s antigen) and formalin-fixed corynebacterium parvum (propionibacterium acnes) bacterin (cpb) against challenge infection with b. rodhaini 3 weeks later. the mice pretreated with s antigen and cpb mixture intraperitoneally, but not intramuscularly, were significantly resistant to intraperitoneal (ip) or intravenous (iv) challenge with 10(6) organisms. t ... | 1989 | 2601229 |
| effect of corynebacterium parvum bacterin on artificial immunity against babesia rodhaini infection in mice. | | 1989 | 2601237 |
| sequence homology of surface membrane proteins of babesia rodhaini. | four surface membrane proteins of babesia rodhaini have previously been shown to induce a degree of protective immunity, and to carry both unique and cross-reactive determinants. cdna clones for two of the genes coding for these proteins have been isolated and used as probes to isolate a single large genomic dna fragment which contained all four genes. dna sequence of two of the genes and their predicted amino acid sequences confirmed that the proteins had hydrophobic sequences at their n- and c ... | 1988 | 2893977 |
| anemia and anti-erythrocyte antibodies developed after repeated injections of sonicated preparations of plasmodium berghei and babesia rodhaini. | anemia developed in mice after repeated injections of sonicated preparations of plasmodium berghei and babesia rodhaini. anti-erythrocyte antibodies were detected in sera by an enzyme-linked immunosorbent assay and their levels rose as anemia developed. administration of carbon particle suspension to block the mononuclear phagocyte system was effective to inhibit anemia induced by injections of sonicated parasite preparations. sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunob ... | 1988 | 3051800 |
| additive effects of tetrocarcin-a and diminazene aceturate concurrently administered against babesia rodhaini-inoculated mice. | | 1988 | 3172611 |
| daily efficacy variation of diminazene diaceturate in mice infected with babesia rodhaini. | | 1988 | 3199625 |
| with time changes of t-lymphocytes after babesia infection in mice pretreated with toxoplasma lysate antigen. | adult female mice of the icr/jcl strain were injected intraperitoneally with an emulsion of toxoplasma lysate antigen (tla; 100 micrograms per head) in light mineral oil (lmo) twice at 2 weeks' interval. each mouse was inoculated intraperitoneally with 10(2) erythrocytes infected with babesia rodhaini 2 weeks after the second injection of the emulsion. the rates of decrease in the erythrocyte count, hemoglobin concentration, and hematocrit value 10 days after inoculation, as compared with the co ... | 1987 | 3310464 |
| development of anti-erythrocyte antibodies in mice infected with babesia rodhaini. | anti-erythrocyte and anti-parasite antibodies were detected in sera of mice infected with a lethal strain of babesia rodhaini by an enzyme linked immunosorbent assay (elisa). both antibodies were produced soon after infection, and their levels increased rapidly in parallel with increasing parasitemias. the number of erythrocytes decreased as parasitemias increased. serum levels of both antibodies increased in mice injected with sonicated parasite antigens derived from infected erythrocytes, but ... | 1987 | 3439388 |
| immunity in neonates of mice chronically infected with babesia rodhaini. | | 1987 | 3573495 |
| the proliferative response of mouse lymphoid tissues during infections with babesia microti or babesia rodhaini. | | 1987 | 3583545 |
| immunity to babesia in mice. iii. the effects of corticosteroids and anti-thymocyte serum on mice immune to babesia rodhaini. | balb/c mice, immunized against babesia rodhaini by an amicarbalide controlled infection, were exposed to selective immunosuppressive treatment with corticosteroids and anti-thymocyte serum (ats) respectively. hydrocortisone acetate, 100 mg/kg, given i.p. six times during the three weeks after challenge inoculation caused a rising parasitaemia and high mortality (6/7). dexamethasone in the drinking water at 20 mg/l or 10 mg/l for 22 days had a similar suppressive effect on the protection against ... | 1985 | 3875924 |
| a double screening trial for the development of drugs against theileria sergenti in cattle using babesia rodhaini and plasmodium berghei in mice. | | 1985 | 3884864 |
| the effect of mitomycin c treatment of infected erythrocytes on infection with babesia microti and babesia rodhaini in mice. | | 1985 | 3920167 |
| viability and virulence of babesia rodhaini eight years after cryogenic preservation with dimethyl sulfoxide. | mouse blood infected with babesia rodhaini and containing an equal volume of 4 m dimethyl sulfoxide was infective after storage at -196 degrees c for 8 years. the babesia organisms were still able to cause lethal infections after prolonged low temperature storage. | 1985 | 4049729 |
| quinuronium levels in ovine plasma as determined by an in vitro/in vivo system with babesia rodhaini. | quinuronium was shown to have a babesicidal activity in vitro. in vitro/in vivo system with babesia rodhaini gave an in vitro ec50 for 13.5 ng/ml. quinuronium levels in ovine plasma increased to a maximum mean of approximately 27 ng/ml at 2 hours with a gradual decay from 8 hours up to almost no detectable levels at 48 hours following administration of therapeutic dose (1 mg/kg s.c.). this study supports previous reports of the use of babesia rodhaini as an organism in screening antibabesials. t ... | 1985 | 4051633 |
| antigenic variants of the haemosporidian parasite, babesia rodhaini, selected by in vitro treatment with immune globulin. | | 1973 | 4132544 |
| babesia rodhaini: carbohydrate metabolism and infectivity for rats of cells freed from host erythrocytes. | | 1970 | 4312898 |
| [apropos of "babesia" rodhaini]. | | 1965 | 4379113 |
| morphological studies of babesia rodhaini--infected rat erythrocytes. | | 1974 | 4420878 |
| infectivity and immunogenicity of irradiated babesia rodhaini. | | 1974 | 4449095 |
| proceedings: the effect of mouse haemoglobins of plasmodium berghei and babesia rodhaini infections. | | 1974 | 4607933 |
| function of the spleen in controlling infections of babesia rodhaini in mice. | | 1972 | 4631548 |
| infectivity of plasmodium berghei and of babesia rodhaini to various primates. | | 1973 | 4631764 |
| [evolution of babesia rodhaini in the mouse embryo]. | | 1973 | 4720424 |
| effects of stimulating erythropoiesis in mice infected with babesia rodhaini. | | 1973 | 4761938 |
| comparison of the effects of irradiation and splenectomy on babesia rodhaini infection in mice. | | 1973 | 4762124 |
| the effect of an interferon inducer on experimental mouse piroplasmosis (babesia rodhaini infection). | | 1973 | 4805160 |
| babesia rodhaini: effects of the immune system in mice. | | 1974 | 4815011 |
| serum opsonins and the passive transfer of protection in babesia rodhaini infections of rats. | | 1974 | 4822486 |
| [the multiplication rate of plasmodium berghei, plasmodium vinckei and babesia rodhaini]. | | 1967 | 4972587 |
| [elimination of eperythrozoon coccoides from strains of babesia rodhaini, plasmodium berghei and plasmodium vinckei]. | | 1968 | 4974248 |
| acquired immunity to babesia microti and babesia rodhaini in mice. | | 1969 | 4976873 |
| babesia rodhaini infections in the rat after acute primary parasitaemia. | | 1969 | 4976947 |
| the rate of development of drug resistance in babesia rodhaini. | | 1969 | 4980625 |
| the blood picture resulting from nuttallia (=babesia) rodhaini and nuttallia (=babesia) microti infections in rats and mice. | | 1969 | 4982449 |
| carbohydrate metabolism in babesia rodhaini: differences in the metabolism of normal and infected rat erythrocytes. | | 1969 | 4983048 |
| resistance of mice and rats to challenge by babesia rodhaini after inoculation with irradiated red cells infected with b. rodhaini. | | 1970 | 4989140 |
| resistance of mice and rats to babesia rodhaini challenge after inoculation with irradiated b. rodhaini infected red cells. | | 1970 | 4991940 |
| the effect of a milk diet upon plasmodium berghei, nuttallia (=babesia) rodhaini and trypanosoma brucei infections in mice. | | 1970 | 4994294 |
| immunity of rats and mice following injection with 60co irradiated babesia rodhaini infected red cells. | | 1971 | 4995421 |
| antigenic variation in babesia rodhaini demonstrated by immunization with irradiated parasites. | | 1971 | 5002030 |
| protective effect of haemolytic serum on mice infected with babesia rodhaini. | | 1972 | 5021569 |
| babesicidal effect of basically substituted carbanilides. i. activity against babesia rodhaini in mice. | | 1969 | 5368454 |
| babesicidal effect of basically substituted carbanilides. ii. imidocarb in rats and mice: toxicity and activity against babesia rodhaini. | | 1969 | 5368455 |
| the role of the spleen in relation to natural and acquired immunity to infections of babesia rodhaini in the rat. | | 1969 | 5374706 |
| drug resistance in babesia rodhaini. | | 1970 | 5420131 |
| measurement of the effect of low temperature on protozoa by titration. ii. titration of babesia rodhaini, using prepatent period and survival time, before and after storage at minus 76 degree c. | | 1970 | 5446635 |
| carbohydrate metabolism in babesia rodhaini: investigations with 14c-labeled substrates and enzyme assays. | | 1970 | 5499669 |
| adoptive transfer of immunity to babesia rodhaini by spleen cells from immune rats. | | 1968 | 5729735 |
| the protective activity of serum from immune rats against babesia rodhaini. | | 1969 | 5770073 |
| anaemia, parasitaemia, erythrophagocytosis, and haemagglutinins in babesia rodhaini infection. | | 1966 | 5960106 |
| enzymes of de novo pyrimidine biosynthesis in babesia rodhaini. | the pathway of de novo pyrimidine biosynthesis in the rodent parasitic protozoa babesia rodhaini has been investigated. specific activities of five of the six enzymes of the pathway were determined: aspartate transcarbamylase (atcase: e.c. 2.1.3.2); dihydroorotase (dhoase: e.c. 3.5.2.3); dihydroorotate dehydrogenase (dho-dhase: e.c. 1.3.3.1); orotate phosphoribosyltransferase (oprtase: e.c. 2.4.2.10); and orotidine-5'-phosphate decarboxylase (odcase: e.c. 4.1.1.23). michaelis constants for atcas ... | 1983 | 6134826 |
| the serological differentiation of babesia rodhaini, b. microti and b. muratovi with a fluorescent antibody staining technique. | | 1981 | 6171215 |
| evaluation of a range of antimicrobial agents against the parasitic protozoa, plasmodium falciparum, babesia rodhaini and theileria parva in vitro. | eighteen antimicrobials commonly used in tissue culture were screened in three different protozoan test systems in order to establish their suitability for routine inclusion in protozoal cultivation systems. the human malaria parasite, plasmodium falciparum, was inhibited by more than half the antibiotics tested at concentrations recommended for normal tissue culture use. eight compounds were well tolerated and thus could be used prophylactically to prevent microbial contamination. these antimic ... | 1984 | 6206808 |
| complement does not play a role in promoting babesia rodhaini infections in balb/c mice. | a critical role of c3 and the c3b receptor for the erythrocyte invasion and the development of the parasitemia of b. rodhaini in rats has been described recently (jack and ward 1980a). in the present study the influence of the c system on b. rodhaini infection in balb/c mice is documented. depletion of serum c3 to less than 5% of the normal level by treatment of mice with cof, the c3 inactivator isolated from cobra venom, did not affect the course of b. rodhaini parasitaemia. treatment of mice w ... | 1982 | 6218704 |
| metabolism of babesia parasites in vitro. comparison of several zwitterion buffers for the in vitro incubation of babesia rodhaini. | the effect on the haemoprotozoan parasite babesia rodhaini of adding a zwitterion buffer, hepes, to a basal medium was studied by comparing the glucose uptake, atp concentration, medium ph and infectivity of parasitized rat erythrocytes every 4 h during 24 h incubation in either krebs ringer phosphate (krp) or krp plus 28 mm hepes. krp plus hepes was found to be superior to krp for the maintenance of glucose uptake, erythrocyte atp concentration, medium ph and infectivity of the parasite. having ... | 1982 | 6287987 |
| anemia and thrombocytopenia from corynebacterium parvum-stimulated resistance against malaria, trypanosomiasis, and babesiosis. | nonspecific immunity (nsi) was manifested in rats injected intravenously with killed corynebacterium parvum and challenged with trypanosoma lewisi, plasmodium chabaudi, or babesia rodhaini. the nsi became evident some 5 days after infection as a suppressed parasitemia, a more rapid recovery from patent infection and as enhanced survival among rats infected with b. rodhaini. the c. parvum injections produced anemia and thrombocytopenia with splenomegaly and signs of glomerulonephritis in rats. th ... | 1983 | 6355427 |
| development of a babesia rodhaini mouse assay for quality control of the serum component of a bovine babesiosis vaccine. | the rodent babesia, babesia rodhaini, survived equally well in basal medium containing either 10 per cent rat serum or 10 per cent bovine serum. as a result, a b rodhaini mouse assay is now performed routinely to determine the suitability of batches of bovine serum for use in a commercial babesia bovis vaccine issued in australia. heat inactivation of bovine serum at 56 degrees c for two hours did not affect the survival of either b bovis or b rodhaini. | 1983 | 6665317 |
| immunity to babesia in mice. i. adoptive transfer of immunity to babesia rodhaini with immune spleen cells and the effect of irradiation on the protection of immune mice. | immunisation of balb/c mice against babesia rodhaini by an amicarbalide-controlled infection resulted in a solid immunity which lasted for 216 days. with spleen cells of immune mice protection could be transferred both to naive mice pretreated with cyclophosphamide. treatment of naive mice with cyclophosphamide (300 mg/kg) five days before a lethal b. rodhaini inoculation resulted in over 50% survival. this protective effect of cyclophosphamide is explained by its inhibiting effect on suppressor ... | 1984 | 6730310 |
| metabolism of babesia parasites in vitro. change in adenylate energy charge and infectivity of babesia rodhaini-infected erythrocytes. | studies were undertaken to investigate a possible correlation between the change, during experimental in vitro treatments, in adenylate energy charge (aec) of b. rodhaini-infected erythrocytes and the infectivity of the parasites for mice. when the aec and infectivity of b. rodhaini-infected erythrocytes were modified by incubation in basal salts media containing various substrates, parasite infectivity correlated significantly (r2 = 0.83, p less than 0.01) with change in aec. however, b. rodhai ... | 1984 | 6743142 |
| immune responses to babesia rodhaini in rats. | | 1984 | 6748444 |
| susceptibility of small laboratory animals to babesia rodhaini infections. | | 1982 | 6752507 |
| babesia rodhaini interactions with complement: relationship to parasitic entry into red cells. | | 1980 | 6767771 |
| the role in vivo of c3 and the c3b receptor in babesial infection in the rat. | the critical role of complement (c3) and the c3b receptor in facilitating the in vivo development of parasitemia with babesia rodhaini in rats is documented. depletion of serum c3 to less than 5% of normal levels by treatment of rats with the c3 inactivator isolated from cobra venom markedly delays the onset of parasitemia. treatment of rats with trypan blue, an inhibitor of the c3b receptor, delays the development of parasitemia. conversely, treatment of rats with suramin, a drug that blocks th ... | 1980 | 6965951 |
| metabolism of babesia parasites in vitro. glucose and energy-metabolism and survival of babesia rodhaini in a basal medium with and without adenosine. | during in vitro incubation in krebs ringer phosphate (krp) medium, rat erythrocytes about 20% parasitized with b. rodhaini used two to four times as much glucose as unparasitized erythrocytes. however, the atp concentration and the atp production of parasitized erythrocytes decreased. for example, before incubation the atp concentration in parasitized erythrocytes was significantly higher thant unparasitized erythrocytes, but following 0.5 h incubation it was reduced to about the same as in unpa ... | 1982 | 6981404 |
| babesia rodhaini and plasmodium berghei. a highly active series of chlorophenoxyalkoxy-substituted diamino-dihydrotriazines against experimental infections in mice. | | 1981 | 7023398 |
| metabolism of babesia parasites in vitro. amino acid production by babesia rodhaini compared to plasmodium berghei. | the in vitro amino acid production by babesia rodhaini, plasmodium berghei and uninfected rat erythrocytes was determined following 4 and 18 h of incubation in krebs ringer medium. both parasites produced excess free amino acid. b. rodhaini produced up to 150 times and p. berghei up to 1,100 times as much free amino acid as parasite-free rat erythrocytes. the composition of excess amino acids produced by both parasites had a statistically significant concordance with the amino acid composition o ... | 1982 | 7052039 |
| susceptibility to babesia rodhaini infection due to sex and age of mice. | | 1982 | 7132023 |
| inhibition of babesia spp. by plastics. | five commercially available plastic containers were compared with glass for toxicity toward babesia rodhaini and babesia bigemina. comparisons were made by using infectivity tests in mice (b. rodhaini) and cattle (b. bigemina). low-density polypropylene and polystyrene containers were not toxic, but two of the three polyvinyl chloride containers tested significantly reduced the viability of both species of babesia. plasticizer present in various amounts on the surface of the toxic containers was ... | 1981 | 7224620 |
| comparisons of glucose, sucrose, and dimethyl sulfoxide as cryoprotective agents for babesia rodhaini, with estimates of survival rates. | | 1980 | 7398365 |