| infectivity of plasmodium simium to aotus trivirgatus monkeys and different anophelines. | infections of plasmodium simium were induced in splenectomized and intact aotus trivirgatus griseimembra monkeys by parasitized blood and by sporozoites from anopheles freeborni mosquitoes. eleven of 13 monkeys developed infection after sporozoite inoculation; prepatent periods ranged from 11 to 25 days (mean 15.8 days). comparative infectivity studies indicated that an, freeborni mosquitoes were the most susceptible followed by an. stephensi, an. balabacensis balabacensis, an. maculatus, an. qu ... | 1979 | 120434 |
| erythrocyte membrane alterations induced by plasmodium simium infection in saimiri sciureus: relation to schüffner's dots. | the nature of erythrocyte membrane alterations in plasmodium simium infections was determined employing light microscopy, carbon replication and transmission electron microscopy. light microscopy of giemsa stained preparations shows that infected cells initially acquire a faint stippling (schuffnerization) which becomes pronouced with subsequent parasite development. enlargement of the host cell usually accompanied stippling. both phenomena appear to depend on host cell age since infected mature ... | 1975 | 165280 |
| five species of panamarian monkeys as new experimental hosts for plasmodium simium. | | 1975 | 809569 |
| plasmodium simium:ultrastructure of erythrocytic phase. | | 1976 | 816667 |
| transmission of plasmodium simium to aotus nancymai, a. vociferans, a. azarae boliviensis, and saimiri sciureus boliviensis monkeys. | | 1987 | 3598812 |
| studies on the exoerythrocytic stages of simian malaria. ix. plasmodium simium. | | 1974 | 4212369 |
| [studies on the transmission of simian malaria and on a natural infection of man by plasmodium simium in brazil]. | | 1967 | 4233427 |
| observations on the sporogonic cycle and transmission of plasmodium simium da fonseca. | | 1969 | 4390413 |
| plasmodium simium in the aotus trivirgatus monkey. | | 1973 | 4631556 |
| [a new natural host of plasmodium simium and plasmodium brasilianum: the woolly spider monkey]. | | 1968 | 4974015 |
| anopheles (kerteszia) cruzi, a natural vector of the monkey malaria parasites, plasmodium simium and plasmodium brasilianum. | | 1970 | 4991945 |
| studies on transmission of simian malaria and on a natural infection of man with plasmodium simium in brazil. | | 1966 | 5297817 |
| circumsporozoite protein gene of plasmodium simium, a plasmodium vivax-like monkey malaria parasite. | | 1993 | 8426613 |
| meager genetic variability of the human malaria agent plasmodium vivax. | malaria is a major human parasitic disease caused by four species of plasmodium protozoa. plasmodium vivax, the most widespread, affects millions of people across africa, asia, the middle east, and central and south america. we have studied the genetic variability of 13 microsatellite loci in 108 samples from 8 localities in asia, africa, south america, and new guinea. only one locus is polymorphic; nine are completely monomorphic, and the remaining three are monomorphic in all but one or two po ... | 2004 | 15328406 |
| host switch leads to emergence of plasmodium vivax malaria in humans. | the geographical origin of plasmodium vivax, the most widespread human malaria parasite, is controversial. although genetic closeness to asian primate malarias has been confirmed by phylogenetic analyses, genetic similarities between p. vivax and plasmodium simium, a new world primate malaria, suggest that humans may have acquired p. vivax from new world monkeys or vice versa. additionally, the near fixation of the duffy-negative blood type (fy x b(null)/fy x b(null)) in west and central africa, ... | 2005 | 15858201 |
| plasmodium simium and saimiri boliviensis as a model system for testing candidate vaccines against plasmodium vivax. | observations on plasmodium simium infections in saimiri boliviensis boliviensis monkeys suggest that this host-parasite combination would be a suitable model for the testing of candidate vaccines against plasmodium vivax. to evaluate the normal course of infections, parasitemia in 52 splenectomized s. boliviensis boliviensis monkeys infected with p. simium were analyzed. the mean maximum parasite count for 31 monkeys after injection with trophozoite-infected erythrocytes was 77,580/microl. twent ... | 2005 | 16172496 |
| plasmodium vivax: recent world expansion and genetic identity to plasmodium simium. | plasmodium vivax causes the most geographically widespread human malaria, accounting annually for 70-80 million clinical cases throughout the tropical and subtropical regions of the world's continents. we have analyzed the dna sequences of the csp (circumsporozoite protein) gene in 24 geographically representative strains of p. vivax and 2 of p. simium, which parasitizes several species of new world monkeys. the csp sequences are of two types, vk210 and vk247, which differ by three diagnostic am ... | 2005 | 16227436 |
| zoonotic malaria - global overview and research and policy needs. | the four main plasmodium species that cause human malaria, plasmodium falciparum, plasmodium vivax, plasmodium malariae, and plasmodium ovale, are transmitted between humans by mosquito vectors belonging to the genus anopheles. it has recently become evident that plasmodium knowlesi, a parasite that typically infects forest macaque monkeys, can be transmitted by anophelines to cause malaria in humans in southeast asia. plasmodium knowlesi infections are frequently misdiagnosed microscopically as ... | 2014 | 25184118 |
| first case of a naturally acquired human infection with plasmodium cynomolgi. | since 1960, a total of seven species of monkey malaria have been reported as transmissible to man by mosquito bite: plasmodium cynomolgi, plasmodium brasilianum, plasmodium eylesi, plasmodium knowlesi, plasmodium inui, plasmodium schwetzi and plasmodium simium. with the exception of p. knowlesi, none of the other species has been found to infect humans in nature. in this report, it is described the first known case of a naturally acquired p. cynomolgi malaria in humans.the patient was a 39-year- ... | 2014 | 24564912 |
| natural plasmodium infection in monkeys in the state of rondônia (brazilian western amazon). | simian malaria is still an open question concerning the species of plasmodium parasites and species of new world monkeys susceptible to the parasites. in addition, the lingering question as to whether these animals are reservoirs for human malaria might become important especially in a scenario of eradication of the disease. to aid in the answers to these questions, monkeys were surveyed for malaria parasite natural infection in the amazonian state of rondônia, brazil, a state with intense envir ... | 2013 | 23731624 |
| new potential plasmodium brasilianum hosts: tamarin and marmoset monkeys (family callitrichidae). | non-human primates (nhps) as a source for plasmodium infections in humans are a challenge for malaria elimination. in brazil, two species of plasmodium have been described infecting nhps, plasmodium brasilianum and plasmodium simium. both species are infective to man. plasmodium brasilianum resembles morphologically, genetically and immunologically the human quartan plasmodium malariae. plasmodium brasilianum naturally infects species of non-human primates from all new world monkey families from ... | 2017 | 28187764 |
| simian malaria in the brazilian atlantic forest: first description of natural infection of capuchin monkeys (cebinae subfamily) by plasmodium simium. | in brazil, two species of plasmodium have been described infecting non-human primates, plasmodium brasilianum and plasmodium simium. these species are morphologically, genetically and immunologically indistinguishable from the human plasmodium malariae and plasmodium vivax parasites, respectively. plasmodium simium has been observed naturally infecting monkeys of the genera alouatta and brachyteles in a restricted area of the atlantic forest in the south and southeast regions of brazil. however, ... | 2015 | 25889933 |
| non-human primate malaria parasites: out of the forest and into the laboratory. | the study of malaria in the laboratory relies on either the in vitro culture of human parasites, or the use of non-human malaria parasites in laboratory animals. in this review, we address the use of non-human primate malaria parasite species (nhpmps) in laboratory research. we describe the features of the most commonly used nhpmps, review their contribution to our understanding of malaria to date, and discuss their potential contribution to future studies. | 2016 | 27748213 |
| identification of a vir-orthologous immune evasion gene family from primate malaria parasites. | the immune evasion gene family of malaria parasites encodes variant surface proteins that are expressed at the surface of infected erythrocytes and help the parasite in evading the host immune response by means of antigenic variation. the identification of plasmodium vivax vir orthologous immune evasion gene family from primate malaria parasites would provide new insight into the evolution of virulence and pathogenesis. three vir subfamilies viz. vir-b, vir-d and vir-g were successfully pcr ampl ... | 2014 | 24477117 |
| detection of plasmodium in faeces of the new world primate alouatta clamitans. | plasmodium falciparum and plasmodium vivax have evolved with host switches between non-human primates (nhps) and humans. studies on the infection dynamics of plasmodium species in nhps will improve our understanding of the evolution of these parasites; however, such studies are hampered by the difficulty of handling animals in the field. the aim of this study was to detect genomic dna of plasmodium species from the faeces of new world monkeys. faecal samples from 23 alouatta clamitans from the c ... | 2016 | 27580347 |
| plasmodium simium, a plasmodium vivax-related malaria parasite: genetic variability of duffy binding protein ii and the duffy antigen/receptor for chemokines. | plasmodium simium is a parasite from new world monkeys that is most closely related to the human malaria parasite plasmodium vivax; it also naturally infects humans. the blood-stage infection of p. vivax depends on duffy binding protein ii (pvdbpii) and its cognate receptor on erythrocytes, the duffy antigen receptor for chemokines (hdarc), but there is no information on the p. simium erythrocytic invasion pathway. the genes encoding p. simium dbp (psdbpii) and simian darc (sdarc) were sequenced ... | 2015 | 26107662 |
| plasmodium simium/plasmodium vivax infections in southern brown howler monkeys from the atlantic forest. | blood infection by the simian parasite, plasmodium simium, was identified in captive (n = 45, 4.4%) and in wild alouatta clamitans monkeys (n = 20, 35%) from the atlantic forest of southern brazil. a single malaria infection was symptomatic and the monkey presented clinical and haematological alterations. a high frequency of plasmodium vivax-specific antibodies was detected among these monkeys, with 87% of the monkeys testing positive against p. vivax antigens. these findings highlight the possi ... | 2014 | 25099335 |