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malaria in illinois. 197719393
relation between malaria serum gamma-globulin concentration and the d-xylose absorption test.d-xylose excretion after a 25 g. oral load was determined in 15 african subjects suffering from malaria. nine of them were re-investigated after the malaria had been or was being treated. malarial parasitaemia and pyrexia did not significantly influence results of the d-xylose test. however, in the untreated subjects, there was a significant inverse correlation between the weight of d-xylose excreted and the serum gamma-globulin concentrations. the observation may have a nutritional importance.197549959
[proteinuria in quartan malaria-infected aotus monkeys].this paper describes the characterization of proteinuria in aotus monkeys infected with quartan malaria (plasmodium brasilianum), using a micro-disc-electrophoresis system. in the post infection urine samples, increases in total proteinuria, albuminuria and gamma-globulinuria were noted a few weeks after peak parasitaemia. two new proteins also appeared in the urine of malaria infected animals. these findings are discussed with reference to the belief that the aotus-p. brasilianum system can be ...197556072
fetal haemoglobin and malaria. 197764740
malaria and immunology. 197881994
immunopathology of malaria. 197898476
antimalarial properties of floxacrine, a dihydroacridinedione derivative.evaluations of the activities of floxacrine [7-chloro-10-hydroxy-3-(4-trifluoromethylphenyl)-3,4-dihydroacridine-1,9(2h, 10h)-dione] in owl monkeys infected with trophozoites of a chloroquine-quinine-resistant strain of plasmodium falciparum, a strain of this plasmodium resistant to both of these quinolines and pyrimethamine, or a strain of p. vivax resistant only to pyrimethamine showed that: (i) this compound regularly effected temporary clearance of parasitemia at daily doses of 1.25 to 2.5 m ...1979117747
[current information on treatment and prophylaxis of malaria (author's transl)].malaria is not a disease of the past. as long as worldwide eradication has not been achieved there is a close connection between countries which export it and those which import it. if the european doctor is presently confronted with a feverish disease which may have been brought in from a tropical area, he should immediately think of malaria and take the necessary measures for treatment. if patients or travelers come into the office and enquire about drugs and preventive measures against malari ...1979120502
parasitic infections and the genitourinary tract. 1975124862
[introduction of malaria into the rsfsr]. 1975126355
[strategy for worldwide eradication of malaria]. 1976129142
the kidney in infectious diseases. 1976129758
clinical and experimental investigation of immune complexes in malaria. 1976133011
[renal involvement in malaria (author's transl)].malaria infection leads to renal involvement. reversible proteinuria accompanies many plasmodial infections. chronic malarial nephrotic syndrome is specifically associated with quartan malaria. acute renal failure is restricted to infections with plasmodium falciparum. the pathogenesis of renal involvement during malarial infections includes immunological mechanisms. it is now realized that there exist at least two types of immunological processes: acute transient immune-complex glomerulonephrit ...1976135874
[results of an immunological examination of the population of the moldavian ssr in connection with cases of inoculation quartan malarian]. 1978149903
abnormal haemoglobins in the sudan savanna of nigeria. iii. malaria, immunoglobulins and antimalarial antibodies in sickle cell disease.subjects with sickle cell disease were identified in (i) a whole population sample (2742) garki district, kano state, nigeria, and in (ii) the 534 infants born into the population during five years. eleven (2.1%) newborn had hb.ss, as was expected from gene frequency (0.146). prevalence was maintained in the first year of life, but fell to 0.4% at one to four years and to 0.05% (one person) over the age of nine years. antimalarial intervention for two transmission seasons was followed by an appa ...1979315213
malaria and hereditary ovalocytosis.hereditary ovalocytosis in papua new guinea is restricted to areas of endemic malaria and may confer increased resistance to the disease. the incidence of malaria was investigated in 1616 melanesiams of known red cell morphology and severity of infection determined in a smaller subsample. ovalocytics tended to be more resistant to severe malarial infections than normocytics. the ratio of parasitaemia in 112 ovalocytics compared with 741 normocytic children was 1.05 for p. falciparum; 0.90 for p. ...1977328370
the prevention and treatment of malaria. 1977329080
the nephrotic syndrome in malawian blacks.this study deals with the nephrotic syndrome in 34 malawian blacks, plasmodium malariae infection and the use of mercury-containing skin lightening creams (butone 3) must be included among the usual causes of nephrotic syndrome in the malawian black.1977331510
malaria control in the labour forces of the tan-zam railway. 1977333667
[identification of plasmodial antibodies in the immunodiagnosis of malaria (author's transl)].out of 880 sera which were examined for antibodies to plasmodia 69 (7.8%) reacted only with p. falciparum antigen, 371(42.2%) reacted only with p. fieldi antigen, and 440 (50%) responded to both antigens. these groups were differentiated further with antigens from p. vivax, p. ovale, and p. malariae. the results showed that the p. ovale antigen was distinguished by a marked activity with those sera that had reacted only with p. fieldi in the screening test. with sera that had responded to both a ...1977337074
the duffy blood group and malaria prevalence in gambian west africans.erythrocytes from 1,168 donors, comprising almost the entire populations of two rural gambian villages, have been tested for duffy blood group antigens using antisera to both fya and fyb. all tests were negative. blood film examination of the same samples showed complete absence of plasmodium vivax parasitaemia, but infections with p. falciparum,p. malariae and p. ovale were observed. the findings are consistent with the view that the duffy-negative phenotype, fyfy, constitutes the basis of inna ...1977339418
plasmodium malariae in kerala and tamilnadu states of india (1969--75) 1977339425
[malaria; a summary]. 1978348605
topical aspects of the epidemiology of malaria. 1978355188
immunopathology of human malaria. 1978355197
[individual prevention of malaria by means of drug therapy]. 1978358609
the malaria burden and population growth in the solomon islands.this paper outlines the result of the control of infectious diseases, and more especially malaria, on the growth of populations in the solomon islands since 1931, the year of the first census, to 1976, the year in which the fourth census revealed, that a population explosion had occurred, and was occurring unabated.1978358655
malumfashi endemic diseases research project. ii. malariometry in malumfashi, northern nigeria.prior to longitudinal studies into the effects of malaria upon the immune response, nutritional status and haematological indices in young children in northern nigeria, the degree of malarial endemicity in the area has been established. field work was carried out in the wet seasons of 1976 and 1977 and the dry season of 1977 (april). seasonal variation in transmission has been demonstrated. age-specific parasite prevalence rates and splenic indices confirm previous studies that this northern par ...1978358930
detection and measurement of species-specific malarial antibodies by immunofluorescence tests.species-specific serodiagnosis of malaria could be made by means of the standardized indirect fluorescent antibody test, either by determination of the usual end-point titres or by fluorescent intensity measurements on antigens. the malarial antibody levels could also be measured by the fluorescent intensity measurements at a single serum dilution. thus the fluorescent intensity measurements could effectively replace the end point titre determination, with the advantages of standardization and s ...1978364784
longitudinal serological study of malaria in infants in the west african savanna. comparisons in infants exposed to, or protected from, transmission from birth.two infant populations, the one exposed to intense malaria transmission and the other protected, were followed and compared by six serological tests. the igg and igm levels increased with age and were systematically, though only slightly, lower in the protected children. the results of three plasmodium falciparum tests (precipitin, indirect fluorescent antibody (ifa) and indirect haemagglutination and one p. malariae test (ifa) were high at birth and decreased rapidly afterwards in both populati ...1978365385
[congenital malaria in a greek twin (author's transl)].a case of congenital malaria due to plasmodium malariae in one of two living greek twins born in germany is presented. in the child fever, anaemia and hepatosplenomegaly were first noticed at the age of two months. plasmodium malariae parasites were demonstrated in the peripheral blood and bone marrow. the sera of mother and infant contained malaria antibodies. however the mother never showed clinical signs of malaria. diagnosis and therapy of congenital malaria and the possible mode of transmis ...1979368608
distribution of human plasmodia in karnataka and tamil nadu states in the reappearing phase of malaria in 1970 and 1975. 1979372102
occurrence of malaria acquired during travel abroad among american civilians, 1970-1976. 1979374645
circulating and tissue-bound immune complex formation in murine malaria.immune complex formation during plasmodium berghei infection of of1 mice was investigated. circulating immune complexes (cic) were detected by the clg-binding assay and the conglutinin-binding solid-phase assay in lethal or drug-limited infections. cic appeared on day 9 of infection, peaked on day 11, and disappeared only after complete cure of the infection. analysis of the immune complexes detected by the clq-binding assay revealed the following characteristics: sedimentation coefficients of 1 ...1979376733
[errors in the diagnosis of malaria]. 1979377805
[aspects of malaria epidemiology in the people's democratic republic of yemen]. 1979384190
[successes of modern malariology].malariological situation analysis in the ussr and world over testifies to increasing malaria incidence particularly in the countries where earlier it was almost fully eradicated. malaria epidemics in these countries (posteradication epidemics) is a new phenomenon in malariology. temporary success of the global campaign of malaria eradication has led to a deadlock in malariology which during the past 10 years is being successfully overcome. achievements of modern malariology are reviewed in the a ...1979386234
treatment and chemoprophylaxis of malaria. 1979392489
quartan malarial nephrotic syndrome in children.quartan malarial infection causes an immune complex nephritis in some individuals, which, once established, is sustained by mechanisms not yet fully explained, but which probably involve autoimmune processes. the presenting clinical and biochemical findings of the quartan malarial nephrotic syndrome are similar to those classically described for the nephrotic syndrome in childhood, but the renal pathology seen on light, electron, and immunofluorescent microscopy show striking differences and dis ...1979393890
[central nervous system involvement in parasitic tropical diseases]. 1979393944
caps jottings on malaria. 4. ronald ross. 1979396986
simultaneous propagation of p. malariae and p. falciparum in a continuous culture. 1979398344
focal outbreak of plasmodium malariae infection in rohtak district (haryana). 1979398348
[plasmodium malariae infection due to exchange transfusion (author's transl)].a four month old baby with plasmodium malariae infection thought to be due to exchange transfusion is presented.1979399992
[imported cases of malaria at the central university hospital of nantes (1968-1978)]. 1979400400
transfusion malaria as a consequence of the 1974 war between turkey and greece--two cases.two cases of transfusion induced plasmodium malariae malaria that occurred in august and september 1974 in new york city were direct results of the outbreak of war between turkey and greece on the island of cyprus in july 1974. the cases could be traced to two greek immigrants with latent infection (one being the longest ever recorded) who independently donated blood after solicitation for people in need living in the country of their ancestors. in view of current rules for donor acceptability, ...1976769569
editorial: transfusion malaria in developing countries. 1976769889
sero-epidemiological surveillance of disappearing malaria in greece. 1975772232
a new look at the protection of hemoglobin as and ac genotypes against plasmodium falciparum infection: a census tract approach.a total of 4,097 randomly selected children under 5 years in accra, ghana were investigated for hb type, malarial parasite species, and parasite density. even though malarial infection rates in this metropolitan population were lower as compared to holoendemic areas, the differential survival of hb s carriers was confirmed. in addition, similar but less pronounced survival effects were seen in hb c heterozygotes. hb s carriers had the highest infection rates. more females than males were infecte ...1976773175
editorial: renal lesions in human malaria. 1976776349
letter: transfusion malaria and immigrant blood donors. 1976778305
a focus of hyperendemic plasmodium malariae-p. vivax with no p. falciparum in a primitive population in the peruvian amazon jungle.findings in a sample population in southeastern peru with a very high rate of malaria infection, due to plasmodium malariae and p. vivax with apparently no p. falciparum, are described. the proportion of persons with p. malariae in this sample population, as determined by slide examination, appears to be the greatest ever reported for any area before the introduction of control measures. although very few p. vivax were found on stained slides, results of the indirect immunofluorescence test indi ...1975779996
studies on the resistance of malaria to chloroquine and to a combination of chloroquine and pyrimethamine in peninsular malaysia.in vivo chloroquine resistance surveys, which allowed for detection of late recrudescing ri resistance, were conducted in three regions of peninsular malaysia, which were previously not recognized as having appreciable drug resistance. among the 485 plasmodium falciparum infections tested resistance rates ranged locally from 20% to 67% in those with parasitaemias over 1,000 per mm3, and 5% to 59% in all parasitaemias. the region found to have the most serious resistance was western pahang. in on ...1976785725
a study of the clinical features of malaria in rhodesia. part iii. african children. 1976786460
transfusion-induced malaria from an asymptomatic carrier.an asymptomatic malaria carrier who satisfied the currently recommended standards and criteria of the american association of blood banks for blood donation was the source of the transfusion-induced malaria in this study. the risk of transfusion-induced malaria remains a very real threat in the united states. any case of unexplained fever following transfusion should be considered as possibly caused by malaria. delay of the proper diagnosis may be due to unfamiliarity of medical personnel with d ...1976790686
differential protein clearances and response to treatment in nigerian nephrotic children.remission followed prednisolone therapy in 9 out of 21 nigerian children with the nephrotic syndrome who had highly selective proteinuria (cg/ca less than 15%). of these, 5 patients have remained well off all treatment during a follow-up of nearly 5 years, 4 have relapsed more than once but have responded to further courses of prednisolone. 3 of 21 with less selective proteinuria also remitted but all relapsed and only one of these has responded again. the other two have relapsed and further cou ...1976793539
aspects of tropical paediatrics.malnutrition interacting with infectious and parasitic diseases are the main causes of the appalling mortality in childhood in the tropics. the most important single safeguard against these in infancy is breast feeding and the trend now evident to abandon this is a disaster which demands urgent attention. reasons for this trend are discussed. efforts to control infectious diseases, other than smallpox, have had little success and the emergence and spread of dengue haemorrhagic fever in s.e. asia ...1976795103
an evaluation of malaria fluorescent antibody patterns in several remote island populations of the new hebrides, solomons, western carolines, and new guinea.from a representative sampling of several remote populations living on the banks and torres islands (new hebrides), the eastern and southern districts of the solomon islands, the western caroline islands (u.s. pacific trust territory), west new guinea (indonesia), and papua new guinea, 752 sera were examined for fluorescent antibodies to the four species of human malaria, and the results were compared to already published parasite survey data based on blood smears and medical examinations. antib ...1976795310
a comparative study of the efficacy of chloroquine and a combination of dapsone and pyrimethamine in the prophylaxis of malaria in peninsular malaysia. 1976796479
malaria parasites of rodents of the congo (brazzaville): plasmodium chabaudi adami subsp. nov. and plasmodium vinckei lentum landau, michel, adam and boulard, 1970.descriptions are given of the blood forms, sporogonic stages and enzyme forms of plasmodium chabaudi adami subsp.-nov. and p. vinckei lentum, malaria parasites of the thicket-rat thamnomys rutilans of the brazzaville region. the two species differ from each other in both morphological and enzymic characters. p.c. adami and p. v. lentum differ from the other subspecies of p. chabaudi and p. vinckei principally by their enzyme forms.1976800328
parasitological review. experimental monkey hosts for human plasmodia. 1975807483
studies on human malaria in aotus monkeys. vi. infectivity of plasmodium malariae to different anophelines.anopheles freeborni, a. balabacensis balabacensis, a. atroparvus, a. stephensi, and a. maculatus mosquitoes were infected by feeding on 12 aotus trivirgatus monkeys infected with a nigerian strain of plasmodium malariae. comparative infectivity studies indicated that the first 2 species were the most heavily infected.1975810562
malarial infections in aotus trivirgatus with special reference to renal pathology. ii. p. falciparum and mixed malaria infections.this paper describe the renal pathology in aotus trivirgatus (owl monkeys) following p. falciparum infections and also when the initial p. falciparum was followed by infection with p. malariae or p. brrasilianum. acute p. falciparum infections were associted with high parasitaemia but relatively mild changes in the glomeruli. this was also the case when a second infection with p. falciparum was given after the first infection had been terminated with chloroquine. four monkeys with multiple infec ...1975813757
malarial infections in aotus trivirgatus with special reference to liver pathology. 1976819657
[serodiagnosis of malaria (author's transl)].homologous and heterologous malaria pathogens were used as antigens for the determination of malaria antibodies by indirect immunofluorescence. homologous antibodies fell in the second half year, after successful treatment, down to the limit of demonstrability. in inhabitants of endemic malarial areas, who lived in the german federal republic, signs of a fall in antibodies could be observed after about 30 months. the predominance of particular malaria pathogens of the country of origin was recog ...1976823409
the quartan malarial nephrotic syndrome.a specific relationship between p. malariae and the nephrotic syndrome, originally postulated on epidemiologic evidence, has been substantiated by clinical, pathologic and immunologic observations. it would appear that quartan malaria causes an immune complex nephritis in some individuals that, once established, is sustained by mechanisms not yet fully explained but which may involve an autoimmune process. evidence to support an immunologic pathogenesis of the renal lesions is provided by the pr ...1976828446
chloroquine resistant malaria in west malaysia.chloroquine resistance is a well established entity in south east asia, and presents a problem of increasing importance. strains of p. falciparum resistant to chloroquine have also been found to be resistant to amodiaquine and a combination of pyrimethamine and sulphadoxine. knowledge of the drug sensitivity of the strains of malaria parasite in a given locality is important so that the right choice of drugs can be made in treatment of the disease. the treatment of chloroquine resistant malaria ...19751095776
[evaluation of malaria diseases]. 19751099424
applications of immunofluorescence to the seroepidemiology of malaria. 19751101775
letter: malaria in britain. 19751102056
the treatment of malaria. 19751105541
[subclinic infections and low parasitemia (plasmodium malariae)]. 19751105828
epidemiology and control of malaria in malaysia.in spite of more than 30 years of control activities, malaria continues to be the most important parasitic infection in malaysia, accounting for 39,189 confirmed cases in 1991, giving an annual parasite incidence rate of 2.2 per 1,000 population. some factors contributing to the continued transmission of malaria are the development of drug resistant plasmodium falciparum, changes in vector behavior, and ecological changes due to socio-economic reasons. malaria parasite rates are higher among the ...19921298064
detection of circulating plasmodial antigens in human sera by sandwich elisa with monoclonal antibodies.two monoclonal antibodies (mabs), one produced against plasmodium falciparum (pf-ig8) and the other against p. cynomolgi (pc-ie12) schizont antigens were used in a sandwich elisa for the detection of circulating plasmodial antigens in sera of patients infected with either p. falciparum, p. vivax or p. malariae. the mean +/- sd optical density (od) values for the normal control group using pf-108 and pc-1e12 were 0.351 +/- 0.036 and 0.205 +/- 0.044, respectively. mean od values for the three infe ...19921298082
[25 years of the eradication of malaria in spain]. 19921301679
[malaria imported into turin: epidemiological observations (1980-1990)]. 19921306171
placental malaria and pregnancy outcome.malaria parasitemia was assessed in 312 placentae of singleton deliveries in benin. the prevalence rate was 45.19%. the dominant infecting specie was plasmodium falciparum. high density parasitemia of placental smear in 44.68% was associated with preterm delivery, low birthweight, intrauterine growth retardation and neonatal mortality. placental histological diagnosis of malaria in 57.69% was more frequently associated with intrauterine growth retardation. extraplacental parasitemia decreased bu ...19921350539
prevalence and level of antibodies to the circumsporozoite proteins of human malaria parasites, including a variant of plasmodium vivax, in the population of two epidemiologically distinct areas in the state of acre, brazil.a seroepidemiological study of the prevalence of antibodies against the repeating epitopes of circumsporozoite (cs) proteins of human malaria parasites was conducted in 2 different areas in the state of acre, brazil in 1987 and 1990. in 1987 antibodies against the cs protein of the vk 247 variant plasmodium vivax as well as antibodies against the cs proteins of p. falciparum and the classic p. vivax were found at relatively high rates in the 2 areas, but significant microepidemiological differen ...19921373529
[the detection and characterization of drug resistant malaria parasites using genetic markers]. 19921404941
malaria. getting into the liver. 19921406943
[rapid diagnosis of malaria. the microwave furnace].thick blood is a well known method for malaria diagnosis, very faithful and sensitive, but it could not be used in emergency because it had to dry for many hours. micro-wave over allows a quick drying (two minutes). do it can now be used in emergency.19921422273
testing to begin on malaria vaccine. 19921439766
appearance of adherent cells suppressive to erythropoiesis during an early stage of plasmodium berghei infection in mice.we examined the effect of adherent cells from bone marrow or spleen of mice infected with plasmodium berghei on dyserythropoiesis. significant reduction in number of erythroid progenitors (erythroid colony-forming units: cfu-e and erythroid burst-forming units: bfu-e) was observed in bone marrow as early as 1 day after p. berghei infection. when adherent cells were removed from bone marrow or spleen cells of infected mice, the number of cfu-e and bfu-e was clearly increased. furthermore, additio ...19921439968
imported malaria in the bronx: review of 51 cases recorded from 1986 to 1991.the cases of 51 patients with malaria seen at the albert einstein college of medicine hospitals from january 1986 to june 1991 are reviewed. thirty-five patients acquired infection on journeys to their country of origin. of these 35 patients, 83% of whom had lived in the united states for > or = 2 years, only 17% received antimalarial prophylaxis. ten of the 51 patients were born and raised in the united states, and 70% received prophylaxis (p < .01). six of the 51 patients were visitors to the ...19921445975
[nephrotic syndrome caused by plasmodium malariae infection. a case with favourable outcome]. 19921454769
comparison of the quantitative buffy coat technique with the conventional thick blood film technique for malaria case detection in the field.the quantitative buffy coat (qbc) technique was compared with the conventional thick blood film technique in a malaria survey carried out in a mesoendemic area of malaria in betau, pahang, malaysia. the qbc technique was found to be a rapid technique but had a sensitivity of about 56% and a specificity of 95%, using the thick blood film method as the "gold standard". malaria species identification was unsatisfactory with the qbc technique as it could identify parasites correctly in only about 60 ...19921455266
[plasmodium falciparum or p. malariae parasitemia in carriers of sickle cell trait in various benin biotypes].the prevalence of malaria and the frequency of gene s were surveyed in two different regions of benin, savana and coastal lacustrine regions. in both regions, prevalence of malaria was not significantly different between hb aa people and hb as people. gene s prevalence was not modified by age, excepted for hb ss which was not found in people upper than 25 years. in holoendemic area, i.e. lacustrine region, means of p. falciparum parasitaemia were significantly lower in hb as children than in hb ...19921462031
[18th century description of malaria]. 19921462580
on-site diagnosis of plasmodium falciparum, p. vivax, and p. malariae by using the quantitative buffy coat system.the quantitative buffy coat (qbc) system was used for the detection and identification of malaria parasites in blood specimens from 570 residents of oksibil, an isolated highland valley in the eastern jayawijaya mountains of irian jaya (indonesian new guinea). the availability of a battery-powered centrifuge and a fiberoptic paralens enabled us to complete and interpret the assay in this remote environment. of 322 qbc tubes examined for 2-4 min each, results of 295 (92%) concurred with findings ...19921491313
malaria--the mime revisited: fifteen more years of experience at a new york city teaching hospital.purpose and patients: a previous review of the new york hospital experience with malaria during 1968 to 1975 summarized clinical and parasitologic features in 24 travelers and highlighted deficiencies in both chemoprophylaxis and diagnosis. to extend this original study, we describe 86 patients with malaria seen at the same hospital during the subsequent 15 years. results: eighty patients were infected with a single plasmodium species, and 60% had plasmodium falciparum infection primarily acquir ...19921524074
parasitology. skirmishes on the border. 19921560820
[autochthonous malaria in brittany]. 19921596964
the effect of splenectomy on immunity to plasmodium malariae and p. falciparum in a malaria immune donor.a 55 year old liberian male was splenectomized after an abdominal trauma. a few days after splenectomy he experienced a pure plasmodium malariae infection with high fever. he was later followed for 12 months with monthly blood films and temperature measurements, and did never show any signs of clinical malaria. the parasite densities observed during the longitudinal follow after splenectomy did not differ from parasite densities in villagers with intact spleens.19921598514
epstein-barr virus transformation of saimiri sciureus (squirrel monkey) b cells and generation of a plasmodium brasilianum-specific monoclonal antibody in p. brasilianum-infected monkeys.the new-world monkeys saimiri sciureus (squirrel monkeys) are currently used as a model to test the efficacy of vaccines against human malaria. to improve our knowledge on this model, we tested the susceptibility of s. sciureus b cells to epstein-barr virus (ebv) infection. b-lymphoblastoid cell lines were obtained from six of six healthy animals after infection with the b95-8 source of ebv. the frequency distributions of spleen b cells clonally committed to the production of immunoglobulins m a ...19911646769
plasmodium falciparum and p. malariae epidemiology in a west african village.transmission of plasmodium falciparum and p. malariae was studied in a village in burkina faso. consecutive captures of mosquitos were organized twice a month over a year and the species of the mosquitos identified. also, the prevalences and densities of plasmodium spp. were determined every 2 months in a sample of children who lived in the village. anopheles gambiae, a. funestus, and a. nili were the local vectors, but only the first two played a predominant role in both p. falciparum and p. ma ...19911677615
in vivo platelet aggregation in acute malaria.thirteen patients suffering from acute malaria attack and thirteen apparently healthy human volunteers (control) were used for the study. platelet aggregation was determined by platelet count ratio technique in which a reduction in platelet count ratio signified an increase in platelet aggregation. platelet count ratio in acute malaria patients was 0.75 +/- 0.03 (sem). platelet count ratio in subjects used as control was 0.88 +/- 0.02. this value was significantly higher than the former (p less ...19911685303
multiple antigen peptides for specific detection of antibodies to a malaria antigen in human sera.multiple antigen peptides (map), consisting of a number of peptide copies synthesized on a branching lysyl core, offer a novel approach for rendering small peptides immunoreactive in solid-phase immunoassays. an octameric map, carrying 6 repeats of the sequence -n-a-a-g-, tandem repeated in the immunodominant region of the circumsporozoite (cs) protein of plasmodium malariae, was used as a model to evaluate the suitability of the map system in an indirect enzyme-linked immunosorbent assay (elisa ...19911720420
reassessment of blood donor selection criteria for united states travelers to malarious areas.in the united states (us), travelers who have had malaria or who have taken antimalarial chemoprophylaxis are deferred as blood donors for 3 years to prevent transfusion-transmitted malaria. to assess the impact of shortening this 3-year exclusion period, national malaria surveillance data from 1972 to 1988 were reviewed. the average annual rate of transfusion-transmitted malaria is 0.25 cases per million units of blood collected. of 45 reported cases, 38 percent were caused by plasmodium malari ...19911755083
laboratory diagnosis of malaria.diagnostic procedures for the detection of malaria differ considerably depending on the aims of evaluation. the current requirements of any laboratory procedure for general application to the detection and diagnosis of malaria include: sensitivity, specificity, simplicity in application, unambiguous interpretation, and rapid turn-around time. presently the differential stained thick and thin blood smear, examined under the microscope, remains the most reliable and definitive test for diagnosis o ...19911802530
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