| use of micro-elisa for quantitating antibody to trypanosoma cruzi and trypanosoma rangeli. | of 229 residents of a panamanian village where both trypanosoma cruzi and trypanosoma rangeli are endemic, 52% had antibody to one or both species by the enzyme-linked immunosorbent assay (elisa), 26% were positive by complement fixation, 17% were positive by direct agglutination, and 32% were positive on the basis of clinical impression. although the sensitivity of elisa makes it the procedure of choice for sero-epidemiologic studies, there does appear to be some serologic cross-reactivity betw ... | 1979 | 116559 |
| a trypanosome, indistinguishable from trypanosoma rangeli, in the haemolymph of rhodnius domesticus from brazil. | | 1977 | 339424 |
| search for trypanosoma rangeli in endemic areas of trypanosoma cruzi in argentina and brazil. | because the presence of trypanosoma rangeli in argentina and brazil has not been confirmed, a serach was carried out in man and triatomine insects. fifty-nine of 207 persons (28.5%) were infected when studied with one or more xenodiagnosis (40 triatoma infestans/xenodiagnosis); 0.1% to 13% of 7,821 bugs' feces and 4% of 875 dissected midguts showed t. cruzi in giemsa stained smears. one of 6,980 hemolymph samples and 1/875 salivary glands showed few flagellates which may have originated in the g ... | 1977 | 407809 |
| leishmania herreri sp. n. from sloths and sandflies of costa rica. | leishmania herreri sp. n. is described after isolation in pure culture from blood, viscera and skin of two-toed (choloepus hoffmanni) and three-toed (bradypus griseus) sloths from costa rica. also, it was isolated from the following sandflies: lutzomyia trapidoi, l. ylephiletor and l. shannoni. the amastigote forms were not seen in the final hosts but they were obtained in tissue culture at 33 c. both promastigotes and amastigotes failed to infect hamsters. the new parasite is isolated frequentl ... | 1979 | 448612 |
| [a peruvian strain of trypanosoma rangeli. iii. observations on the experimental infection of panstrongylus herreri wygodzinsky, 1948]. | | 1975 | 1103260 |
| [peruvian strain of trypanosoma rangeli. iv. observations on its development and morphogenesis in the hemocele and salivary glands of rhodnius ecuadoriensis]. | | 1975 | 1105741 |
| letter: growth characteristics of trypanosoma rangeli. | | 1976 | 1265828 |
| characterization of a natural human antibody with anti-galactosyl(alpha 1-2)galactose specificity that is present at high titers in chronic trypanosoma cruzi infection. | an antibody reactive with the galactosyl(alpha 1-2)galactose [gal(alpha 1-2)gal] epitope was characterized in human sera by enzyme-linked immunosorbent assay, red blood cell (rbc) and laminin absorption, and oligosaccharide inhibition. this antibody was found evenly distributed between the igg and igm classes and was present at high titers in the serum of all normal adults studied, but in 75% of children less than three years of age, it was observed at the lower limit of detection, and gradually ... | 1992 | 1279994 |
| the possibility of occurrence of trypanosoma rangeli in the state of tocantins, brazil. | | 1992 | 1343658 |
| trypanosoma rangeli (tejera, 1920): observations upon pleomorphism. | meta-trypomastigotes of trypanosoma rangeli tejera, 1920, harvested from lit medium, were inoculated i.p. or s.c. into 6, 16, and 26 g nmri mice, these representing increasing degrees of immunological maturity. in all cases, similar pleomorphic patterns were observed. four morphobiometrically differentiable types of trypanosome were encountered in an overlapping temporal sequence. these observations, taken in comparison with those on pleomorphism in this and other species of trypanosoma by other ... | 1992 | 1343665 |
| [presence of neuraminidase in rhodnius prolixus infected with trypanosoma rangeli]. | using three different methods, the activity of neuraminidase was studied in the promesenteron, postmesenteron, rectal ampulla, haemolymph and salivary glands in 600 rhodnius prolixus experimentally infected with trypanosoma rangeli stock san agustín. the haemagglutination method with peanut lectin, and the fluorescence test with peanut lectin conjugated with fluorescein isothiocyanate, and the fluorescence emitted by 4-methylumbelliferone showed in all cases the presence of neuraminidase in the ... | 1992 | 1345317 |
| pcr amplification of mini-exon genes differentiates trypanosoma cruzi from trypanosoma rangeli. | synthetic oligonucleotides corresponding to a conserved 22 nucleotide sequence within the tandemly repeated mini-exon gene have been used to amplify a single gene-containing repeat from trypanosoma cruzi and trypanosoma rangeli, two morphologically similar organisms with overlapping hosts and geographical distribution but different pathogenicity in humans. the t. cruzi repeat is 582 nucleotides long and the t. rangeli repeat is 858 nucleotides. the two organisms may therefore be distinguished pr ... | 1992 | 1406732 |
| spliced leader rna sequences of trypanosoma rangeli are organized within the 5s rrna-encoding genes. | the spliced leader rna(sl rna)-encoding genes of the salivarian new world trypanosome, trypanosoma rangeli, are organized within the 5s rrna tandem repeats. each repeat contains genes encoding an sl rna and a 5s rrna in the same orientation of transcription. this sl-5s organization is also present in the african trypanosome, trypanosoma vivax. a similar association of sl and 5s genes has been observed in some nematodes, but has not been described previously in trypanosomatids. | 1992 | 1572544 |
| immune response and trypanosoma cruzi infection in trypanosoma rangeli-immunized mice. | the capacity of trypanosoma rangeli antigens to induce immune response in mice was analyzed and the course of the infection was studied in immunized animals challenged with virulent forms of t. cruzi. balb/c mice were immunized with supernatant of disrupted epimastigotes of t. rangeli and with epimastigotes (epi) of t. rangeli fixed with glutaraldehyde. both of the antigens were emulsified with incomplete freund's adjuvant (ifradj). all of the animals received t. cruzi tulahuen antigens in the f ... | 1991 | 1828328 |
| trypanosoma rangeli (tejera, 1920) isolated from a sylvatic rodent (echimys dasythrix) in santa catarina island, santa catarina state: first report of this trypanosome in southern brazil. | a trypanosome strain isolated from a sylvatic rodent (echimys dasythrix) from santa catarina island (santa catarina state, brazil) was characterized by the following methods: experimental transmission and development in invertebrate and vertebrate hosts, morphometry, cross protection, complement sensitivity, lectin agglutination and isoenzyme profiles. comparisons were made with standard trypanosoma cruzi and t. rangeli strains. all methods except isoenzyme analysis led to the identification of ... | 1991 | 1842404 |
| the distribution of agglutinins and lytic activity against trypanosoma rangeli and erythrocytes in rhodnius prolixus and triatoma infestans tissue extracts and haemolymph. | haemolymph, heads, salivary glands, crops, midguts, hindguts, and malpighian tubules from rhodnius prolixus and triatoma infestans were extracted in phosphate or tris buffer saline with calcium, and tested for agglutination and lytic activities by microtitration against both vertebrate erythrocytes and cultured epimastigote forms of trypanosoma rangeli. haemagglutination activity against rabbit erythrocytes was found in the crop, midgut and hindgut extracts of t. infestans but only in the haemol ... | 1991 | 1842412 |
| schizodeme analysis with the restriction endonuclease rsa i differentiates between trypanosoma rangeli and trypanosoma cruzi. | | 1991 | 1842443 |
| trypanosomatid isolates from honduras: differentiation between trypanosoma cruzi and trypanosoma rangeli. | with the aim of identifying and differentiating trypanosoma cruzi from trypanosoma rangeli, culture epimastigotes from 30 honduran trypanosomatid isolates were analyzed by susceptibility to complement lysis, reactivity to lectins, reactivity to monoclonal antibodies specific for t. cruzi, and isoenzymatic electrophoretic patterns. using these four methodologies, 27 of the 30 trypanosomatid isolates, as well as 5 clones, were identified as t. cruzi, whereas the remaining three isolates were class ... | 1991 | 1907109 |
| the prophenoloxidase system and in vitro interaction of trypanosoma rangeli with rhodnius prolixus and triatoma infestans haemolymph. | the presence of the prophenoloxidase (propo) system in the haemolymph of rhodnius prolixus and triatoma infestans and the role played by trypanosoma rangeli in the in vitro activation of propo were tested. both r. prolixus and t. infestans whole blood preparations showed a very active propo system. the propo cascade of the two insect species were differentially activated by microbial-derived extracts: laminarin was a better activator of t. infestans haemolymph than of r. prolixus blood, and lipo ... | 1991 | 1956701 |
| elevated cerebroside antibody levels in human visceral and cutaneous leishmaniasis, trypanosoma rangeli infection, and chronic chagas' disease. | a natural cerebroside (antic) igm antibody was found at relatively high levels in the serum of every healthy individual studied. the reactivity of the antibody was assessed by using highly purified bovine brain galactocerebroside (galc) or human glucocerebroside (gluc) as antigen. the importance of fatty acid moiety of galc in antigen-antibody reaction was demonstrated by low immunoreactivity using 1-beta-d-galactosyl sphingosine (gs) as antigen and by the absence of absorption to gs-bearing lip ... | 1990 | 2116736 |
| development and interactions of trypanosoma rangeli in and with the reduviid bug rhodnius prolixus. | two strains of trypanosoma rangeli and three strains of rhodnius prolixus were used in various combinations to transmit the trypanosomes via the reduviid bug. a persisting infection in the midgut lumen posterior to the stomach resulted in all 2,500 bugs being third and fourth instars. infectious, metacyclic forms developed exclusively in the salivary glands; forms excreted with bug feces were noninfectious to mice. the midgut epithelium was the main barrier to transmission of the parasite. in on ... | 1990 | 2186407 |
| use of total parasite dna probes for the direct detection of trypanosoma cruzi and trypanosoma rangeli in domicilliary rhodnius prolixus. | | 1990 | 2189249 |
| clinical trypanosoma rangeli infection as a complication of chagas' disease. | laboratory studies on a group of 20 patients from the rio negro valley, colombia selected for detailed study showed that 14 gave antibody reactions on immunoassay consistent with trypanosoma cruzi or t. rangeli infections. four were diagnosed as having t. rangeli infection, 4 had mixed infections and 6 were infected with t. cruzi alone. immunoprecipitation analysis showed that sera from t. cruzi-infected patients recognized a similar range of trypomastigote-derived polypeptides as sera from pati ... | 1987 | 2441341 |
| serological activity against galactosyl-alpha(1-3)galactose in sera from patients with several kinetoplastida infections. | using rabbit erythrocyte-derived neutral glycosphingolipids enriched for a defined ceramide pentasaccharide as antigens, we have detected elevated anti-galactosyl-alpha(1-3)galactose (anti-g alpha g) antibody values in patients with american cutaneous leishmaniasis (acl), chronic chagas' disease, and trypanosoma rangeli infections compared with normal subjects or with patients suffering from any of 15 other infectious diseases. the specificity of the g alpha g antibodies was determined by inhibi ... | 1988 | 2449451 |
| binding of lectins to culture and vector forms of trypanosoma rangeli tejera, 1920 (protozoa, kinetoplastida) and to structures of the vector gut. | culture forms of trypanosoma rangeli could be agglutinated with canavalia ensiformis (con a) lectin and, less effectively with pisum sativum agglutinin (pea), at a concentration of 200 micrograms/ml. ricinus communis agglutinin i (rca i) agglutinated trypanosomes only if they were not previously washed with physiological ringer's solution. three other lectins did not react with the same parasite forms. direct or indirect lectin-gold labeling techniques were applied to lr-white embedded thin sect ... | 1989 | 2689636 |
| characterization of tubulin genes in trypanosoma rangeli. | tubulin genes in trypanosoma rangeli, the only trypanosome besides t. cruzi to infect humans in america, are organized in homogeneous, alternate alpha and beta gene tandem repeats of 3.8 kb. the basic repeat was cloned, mapped and partially sequenced. in contrast to most other eukaryotes, where tubulin genes are scattered throughout the genome, trypanosomatids so far studied are characterized by tandem arrangements of these genes with the genus trypanosoma displaying an alternating alpha- and be ... | 1989 | 2733730 |
| antibody response to experimental trypanosoma rangeli infection and its implications for immunodiagnosis of south american trypanosomiasis. | differential immunodiagnosis of t. rangeli and t. cruzi infections in man poses a particular problem, not only because these parasites share antigenic determinants, as detected by immunofluorescence, but also because they have a similar geographical distribution, the same host range and often identical insect vectors. we show here that whereas mouse anti-t. rangeli sera have significant cross reactivity with t. cruzi by immunofluorescence, they are entirely specific when tested by elisa, using a ... | 1985 | 2868633 |
| action of pyrazolopyrimidine derivatives on trypanosoma rangeli culture forms. | the capacity of 54 different pyrazolo(3,4-d)- or pyrazolo(4,3-d)pyrimidine derivatives to inhibit the multiplication of trypanosoma rangeli culture forms was evaluated. among pyrazolo(3,4-d)pyrimidines, 14 derivatives showed trypanostatic activity, 4-aminopyrazolo-(3,4-d)pyrimidine (app) being the most active, with 4-hydroxypyrazolo(3,4-d)pyrimidine (hpp) lacking trypanostatic activity. 7-hydroxy-3-beta-d-ribofuranosylpyrazolo(4,3-d)pyrimidine (fob) was as active as 7-amino-3-beta-d-ribofuranosy ... | 1986 | 2871991 |
| the affinity of the lectins ricinus communis and glycine maxima to carbohydrates on the cell surface of various forms of trypanosoma cruzi and trypanosoma rangeli, and the application of these lectins for the identification of t. cruzi in the feces of rhodnius prolixus. | flagellates of trypanosoma cruzi (stock molino 1), obtained from the intestine of experimentally infected rhodnius prolixus, grown in cellular or acellular culture, as well as from the blood of infected mice, were examined by a direct fluorescence test using the lectins rca (ricinus communis-120) and sba (soy bean agglutinin; glycine maxima), conjugated with fluorescein isothiocyanate, for the detection of beta-d-galactose and alpha,beta-n-acetyl-d-galactosamine on the membranes of the flagellat ... | 1986 | 2877548 |
| trypanosoma (herpetosoma) leeuwenhoeki in choloepus hoffmanni and didelphis marsupialis of the pacific coast of colombia. | trypanosoma (herpetosoma) leeuwenhoeki, originally described in panamanian sloths, was isolated from didelphis marsupialis (marsupialia) and choloepus hoffmanni (edentata) inhabiting the pacific coast of colombia. trypanosomes were characterized by their large blood forms (total length 51-53 microns), poor infectivity for mice, and lack of development in rhodnius prolixus. isoenzyme studies, with either strains or clones, revealed homogeneous profiles clearly distinct from trypanosoma cruzi and ... | 1989 | 2926591 |
| isoenzymes of trypanosoma rangeli stocks and their relation to other trypanosomes transmitted by triatomine bugs. | culture forms of three trypanosome species, trypanosoma rangeli, t conorhini and t. cruzi, have been compared isoenzymatically by isoelectrofocusing. of 9 enzymes examined, three: nonspecific esterase (nse), phosphoglucomutase (pgm) and glucosephosphate isomerase (gpi), showed species specific enzyme profiles. little isoenzymatic variation was found amongst the 14 t. rangeli stocks examined. two of them were identified as t. cruzi of group i demonstrating the necessity of a clear identification ... | 1986 | 2947314 |
| trypanosoma cruzi and trypanosoma rangeli in saimiri sciureus from bolivia and saguinus mistax from brazil. | examination of blood films for trypanosomes in primates housed at the tulane university delta regional primate research center showed that 47% (32/68) of the bolivian saimiri sciureus and 51% (68/135) of brazilian saguinus mistax harbored one or more types: trypanosoma (schizotrypanum) cruzi in 6% to 7% and trypanosoma (herpetosoma) spp. or trypanosoma (megatrypanum) spp. in 39% and 45%, respectively. trypanosomes were isolated from a sample of the infected monkeys and morphobiological studies w ... | 1986 | 3082228 |
| antibodies to laminin in trypanosoma rangeli-infected subjects. | | 1987 | 3106958 |
| biological activity of analogs of guanine and guanosine against american trypanosoma and leishmania spp. | the growth inhibitory effects of six guanine and guanosine analogs, 3-deazaguanine (compound 1); 3-deazaguanosine (compound 2); 6-aminoallopurinol (compound 3); 9-beta-xylofuranosyl guanine (compound 4); a ribosylated derivative of compound 3, 6-aminopyrazolo(3,4-d)pyrimidin-4-one (compound 5); and 5-aminoformycin b (compound 6), were tested against some pathogenic members of the family of american trypanosomatidae. compounds 1 and 2 were highly active against trypanosoma cruzi, trypanosoma rang ... | 1987 | 3107463 |
| radiolabeled total parasite dna probe specifically detects trypanosoma cruzi in mammalian blood. | a dna-dna hybridization procedure is described in which radiolabeled total parasite dna is used to detect trypanosoma cruzi spotted directly onto nylon membrane. under conditions that favor hybridization of repetitive dna sequences, the radiolabeled total dna was able to detect as few as five parasites spotted onto nylon membrane. trypanosomes were detectable in blood from mice with t. cruzi parasitemias spotted directly onto membranes. all 10 strains of t. cruzi examined, which came from differ ... | 1988 | 3128583 |
| a simple semi-defined culture medium for the growth of trypanosoma rangeli. | | 1988 | 3188152 |
| studies on the cellular immune responses of insects toward the insect pathogen trypanosoma rangeli. | | 1988 | 3280694 |
| trypanosoma (schizotrypanum) cruzi and trypanosoma (herpetosoma) rangeli. i. comparative studies by polyacrylamide-gel electrophoresis. | | 1986 | 3296073 |
| [laboratory maintenance of trypanosoma (herpetosoma) rangeli tejera, 1920]. | two laboratory maintenance systems of trypanosoma rangeli were compared. the maintenance by weekly subinoculations in tobie's culture medium and the intrafemoral inoculation of rhodnius prolixus with cultured flagellates, resulted in loss of infectivity of the metacyclic salivarian trypomastigotes for mice, ten months after maintenance in culture. with the system of cyclical passes through culture-rhodnius-mouse-culture-rhodnius, the infectivity of the metacyclic trypomastigotes for mice, was ma ... | 1986 | 3313550 |
| neuraminidase fluorescence test for the differentiation of trypanosoma cruzi and trypanosoma rangeli. | the cell free supernatants of 13 stocks of trypanosoma rangeli/t. rangeli-like, 50 stocks of t. cruzi/t. cruzi-like and 3 stocks of t. conorhini grown in culture were examined by using the 2-(4-methylumbelliferyl-alpha-d-n-acetylneuraminic acid) test. it could be demonstrated that only the supernatants of the t. rangeli/t. rangeli-like stocks showed a white-yellow fluorescence under uv light. in contrast, the cell free supernatants of the t. cruzi/t. cruzi-like and t. conorhini stocks showed an ... | 1987 | 3327143 |
| studies on trypanosoma rangeli tejera, 1920. ix. course of infection in different stages of rhodnius prolixus. | frequent individual observations od different stages of rhodnius prolixus exposed to trypanosoma rangeli, revealed a higher susceptibility to infection in the bugs exposed during the two first instars. the mortality rate in infected bugs was significantly higher than in controls, indicating that the parasite was responsible for the majority of deaths. an analysis of the mortality distribution, per instar, is presented. statistical analysis of deaths among the different infected instars, showed t ... | 1987 | 3333807 |
| rhodnius neivai: a new experimental vector of trypanosoma rangeli. | rhodnius neivai was as efficient as rhodnius prolixus and rhodnius robustus in transmitting by bite a colombian strain of trypanosoma rangeli following its inoculation into the hemocoel. under conditions of the study the strain of t. rangeli had a high and constant infectivity to the salivary glands of r. prolixus, its natural vector in colombia. six species of triatoma and dipetalogaster maximus likewise inoculated did not develop metatrypomastigotes in the salivary glands. of the 12 known spec ... | 1986 | 3518505 |
| specific inhibition of trypanosoma cruzi neuraminidase by the human plasma glycoprotein "cruzin". | plasma of normal human individuals was shown to contain an inhibitor of trypanosoma cruzi neuraminidase (naase; acylneuraminyl hydrolase, sialidase, ec 3.2.1.18). the inhibitor has been purified to homogeneity by peg precipitation, cm affi-gel blue sepharose chromatography, and gel filtration. the purified preparation inhibits t. cruzi naase at a concentration as low as 10(-9) m and has no effect at concentrations at least 100 times higher on any of the other naases tested, including those from ... | 1987 | 3554230 |
| investigation of the possible role of hemocyte and parasite surface charge in the clearance of trypanosoma rangeli from the insect hemocoel. | | 1987 | 3693944 |
| lack of enzyme polymorphism in trypanosoma rangeli stocks from sylvatic and domiciliary transmission cycles in colombia. | although trypanosoma rangeli is biologically and morphologically distinct from trypanosoma cruzi, these two hemoflagellates are epidemiologically linked. we report the results of enzyme electrophoretic studies of t. rangeli stocks isolated from sylvatic and domiciliary rhodnius prolixus, and infected humans inhabiting foci in which t. cruzi was sympatrically transmitted. t. rangeli stocks displayed electrophoretically detectable polymorphism for only a single enzyme, isocitrate dehydrogenase (ic ... | 1987 | 3812885 |
| [trypanosoma rangeli tejera, 1920. viii. response to reinfections in 2 mammals]. | under experimental conditions, the course of the infection and the response to the reinfection by trypanosoma rangeli in mice and didelphis marsupialis, are studied. during the initial infection the mice show a relatively low parasitaemia and a short patent period. a scanty parasitaemia level of four days length, was observed following the first reinfection, being the mice resistant to new reinfections by t. rangeli. in opossums a lower parasitaemia and a longer patent period than that detected ... | 1985 | 3836326 |
| serine hydroxymethyltransferase activity in trypanosoma cruzi, trypanosoma rangeli and american leishmania spp. | serine hydroxymethyltransferase (shmt) was studied in several american trypanosomatids, trypanosoma cruzi epimastigotes displaying, in contrast with t. rangeli, high enzymatic activity. several leishmania spp. members, including l. braziliensis, l. mexicana and l. garnhami promastigotes, under identical assay conditions, showed low enzymatic activity. the t. cruzi and leishmanial enzymes presented several different kinetic properties, and thus apparent km for thf was 0.30 mm for the trypanosomal ... | 1985 | 3896630 |
| flagellate infections of brazilian sand flies (diptera: psychodidae): isolation in vitro and biochemical identification of endotrypanum and leishmania. | flagellate infections were found in 1,063 of 18,895 sand flies collected in the states of amazonas, pará, rondonia and acre, brazil. infection rates were 13.4% (species group shannoni); 7.5% (subgenus nyssomyia); 6.7% (subgenus lutzomyia series cruciata); 0.5% (genus psychodopygus) and 3.1% for other sand flies (various subgenera). leishmania braziliensis guyanensis and l. mexicana amazonensis were isolated, respectively, from the known vectors, lutzomyia umbratilis and l. flaviscutellata. singl ... | 1985 | 3938924 |
| neuraminidase activity in trypanosoma rangeli. | supernatants of cultures and extracts of trypanosoma rangeli readily release n-acetyl neuraminic acid from a variety of substrates. the activity in both supernatant and cell extract is precipitated between 30 and 50% ethanol, and between 40 and 70% ammonium sulfate. fractionation of the culture supernatant by gel exclusion gives a single peak of neuraminidase activity of molecular weight 48 000. the culture supernatant releases sialic acid at different rates from the following substrates:fetuin, ... | 1985 | 3990712 |
| trypanosoma (herpetosoma) rangeli tejera, 1920: mouse model for high, sustained parasitemia. | the neotropical mammalian parasite trypanosoma (herpetosoma) rangeli tejera, 1920 is difficult to study due to the scarcity of blood forms in the vertebrate host. high and persistent parasitemias (up to 7 times the original inoculum at the peak, and persisting for up to 2 wk) were obtained by i.p. inoculation of infant (6.0 g) male white mice (nmri strain) with 15 x 10(3) trypomastigotes/g body weight from 12-day-old cultures of the "dog-82" strain of t. rangeli. this strain was cultured 15 mo a ... | 1985 | 4032147 |
| [natural infection of panstrongylus megistus (burmeister, 1835) by trypanosoma rangeli (tejera, 1920) in the interior of the state of alagoas]. | | 1973 | 4201998 |
| the prevalence of trypanosomes and microfilariae in panamanian monkeys. | a total of 3,523 wild caught monkeys from panama was examined for blood parasites from august 1968 through june 1972. trypanosomes or microfilariae were observed in the blood of 31.1% of the monkeys. mixed infections, with microfilariae and trypanosomes, were detected in 6.6% of the animals. trypanosoma cruzi was found in marmosets. saguinus geoffroyi (12.2%), in white-faced capuchins, cebus capucinus (5.0%), in squirrel monkeys, saimiri sciureus (1.7%) and in black spider monkeys, ateles fuscic ... | 1974 | 4217567 |
| new experimental vectors of colombian trypanosoma rangeli. | | 1972 | 4560504 |
| prevalence of trypanosoma cruzi and trypanosoma rangeli in triatomines (hemiptera: reduviidae) collected in the republic of panama. | | 1973 | 4567850 |
| [presence of trypanosoma rangeli tejera, 1920, in peru. i. the insect vector rhodnius ecuadoriensis lent & león, 1958]. | | 1972 | 4569344 |
| [study of a peruvian strain of trypanosoma rangeli. i. verification of natural infection in salivary glands of rhodnius eduadoriensis]. | | 1974 | 4602562 |
| [study of a peuruvian strain of trypanosoma rangeli. ii. observations on experimental infection of rhodnius ecuadoriensis]. | | 1974 | 4602563 |
| isoenzymic differences between culture forms of trypanosoma rangeli, t. cruzi, and t. lewisi. | | 1974 | 4608715 |
| [notes on chagas' disease in panama. incidence and distribution of trypanosoma cruzi and trypanosoma rangeli]. | | 1972 | 4634059 |
| division of the human trypanosome, trypanosoma (herpetosoma) rangeli. | | 1973 | 4796916 |
| natural infections and behavior of trypanosoma rangeli and trypanosoma cruzi in the vector rhodnius prolixus in colombia. | | 1969 | 4980776 |
| frequency and distribution of trypanosoma cruzi and trypanosoma rangeli in the republic of panamá. | | 1971 | 4996705 |
| histology of rhodnius prolixus infected with trypanosoma rangeli. | | 1971 | 4997588 |
| observations on the development of trypanosoma rangeli in the hemocoel of rhodnius prolixus. | | 1970 | 5442845 |
| [ultrastructure of trypanosoma rangeli, tejera 1920. forms of culture]. | | 1970 | 5484568 |
| trypanosoma rangeli: effect on excretion in rhodnius prolixus. | | 1971 | 5558074 |
| [new observations on the pathological actions of trypanosoma rangeli tejera, 1920 on rhodniu prolizus, 1859]. | | 1967 | 5598521 |
| pathogenicity of trypanosoma rangeli for rhodnius prolixus stal in nature (hemiptera: reduviidae) (kinetoplastida: trypanosomatidae). | | 1968 | 5699971 |
| biological factors influencing transmission of trypanosoma rangeli by rhodnius prolixus. | | 1965 | 5857287 |
| purified trypanosoma cruzi specific glycoprotein for discriminative serological diagnosis of south american trypanosomiasis (chagas' disease). | chagas' disease, leishmaniasis, and trypanosoma rangeli infection are endemic and their distributions overlap in vast regions of south and central america. serological cross-reactivities can confuse epidemiological studies of these infections, and their differential diagnosis has been assigned a high priority by the world health organisation. a lectin-affinity-purified, 90,000 molecular weight glycoprotein (gp90) is present in the known principal strains (zymodemes) of trypanosoma cruzi and abse ... | 1983 | 6138504 |
| interspecific differentiation of trypanosoma cruzi, trypanosoma conorhini and trypanosoma rangeli by lectins in combination with complement lysis. | four-day-old epimastigote culture forms of trypanosoma cruzi, trypanosoma rangeli and trypanosoma conorhini were tested with 21 lectins. furthermore t. conorhini was incubated with the following sera: rat, wistar han, germ free; normal fresh hen, rat and human serum. t. rangeli was agglutinated only by the d-mannose specific lectins from canavalia ensiformis and pisum sativum. t. cruzi and t. conorhini could be distinguished by the lectin from tridacna crocea. the epimastigote culture forms of t ... | 1984 | 6143480 |
| studies on trypanosoma rangeli tejera, 1920 ii. its effect on feeding behaviour of triatomine bugs. | | 1984 | 6143490 |
| constant and variable regions in dna mini-circles from trypanosoma cruzi and trypanosoma rangeli: application to species and stock differentiation. | | 1981 | 6173749 |
| differential metabolism of allopurinol and derivatives in trypanosoma rangeli and t. cruzi culture forms. | we have compared the metabolism of allopurinol (4-hydroxypyrazolo (3,4-d)pyrimidine; hpp), by trypanosoma rangeli, a non-pathogenic american trypanosome, and t. cruzi, the causative agent of chagas' disease. our results indicate that t. rangeli was unable to animate allopurinol mononucleotide to 4-aminopyrazolopyrimidine (app) mononucleotide. radioactivity was located in the rna, but not the dna, only of t. cruzi. substrate specificity studies showed t. cruzi succino-amp synthetase activity bein ... | 1981 | 6174862 |
| zymodeme and species specificities of monoclonal antibodies raised against trypanosoma cruzi. | a series of hybrid cell lines was generated by the fusion of sp2/0 myeloma cells with spleen cells from balb/c mice that had been immunized or infected with trypanosoma cruzi zymodemes (z1, z2, z3 ). four immunoglobulin isotypes, igm, igg1, igg2a and igg3 were represented amongst the monoclonal antibodies secreted by 22 hybridoma clones. on indirect immunofluorescence (ifat) antibodies bound to flagellum, cytoplasm, cell membrane or stained the whole organism. two antibodies were epimastigote-sp ... | 1984 | 6380014 |
| lectins discriminate between pathogenic and nonpathogenic south american trypanosomes. | cell surface carbohydrates of trypanosoma cruzi, trypanosoma rangeli, and trypanosoma conorhini were analyzed by a micro-agglutination assay employing 27 highly purified lectins and by binding assays using various 125i-labeled lectins. the following seven lectins discriminated between the trypanosomes: 1) tomato lectin (an n-acetyl-d-glucosamine-binding protein), both in purified form and as crude tomato juice; 2) bauhinea purpurea and sophora japonica lectins (both n-acetyl-d-galactosamine-bind ... | 1984 | 6385741 |
| differentiation between trypanosoma cruzi and trypanosoma rangeli on the basis of their sialic acid content. | four day-old culture forms of trypanosoma rangeli strain san augustin were tested with the following lectins: canavalia ensiformis, pisum sativum, ricinus communis-120, sojahispida, aaptos papillata ii, triticum vulgaris, limulus polyphemus, lberis amara and arachis hypogaea. these flagellates were only agglutinated by the lectins from canavalia ensiformis and pisum sativum. furthermore four day-old culture forms of the t. cruzi strains morcego 1354, p-60, téhuantépéc and wa 301/130 as well as t ... | 1984 | 6388083 |
| studies on trypanosoma rangeli tejera, 1920. vii--its effect on the survival of infected triatomine bugs. | the pathological effects of trypanosoma rangeli on rhodnius prolixus and r. robustus, and the relation of mortality to infection, were studied under laboratory conditions. frequent observations revealed that when the first instar nymphs of r. prolixus and r. robustus were infected with t. rangeli, survival of the bugs during the stages of development to the adult stage decreased. this decrease was statistically significant when compared with uninfected control-bugs, indicating that t. rangeli is ... | 1984 | 6399091 |
| studies on trypanosoma rangeli tejera, 1920. vi. developmental pattern in the haemolymph of rhodnius prolixus. | the morphological sequence of trypanosoma rangeli development in the body cavity of rhodnius prolixus is described. the metacyclic trypanosome is the product of successive division and transformation during the intra and extracellular development in the haemocoele. the significance of the early invasion of t. rangeli into the haemolymph is discussed. the epidemiological importance of the developmental pattern of t. rangeli in the vectors haemolymph and the host-response to the parasite are consi ... | 1983 | 6400168 |
| vertebrate hosts and vectors of trypanosoma rangeli in the amazon basin of brazil. | a total of 46 trypanosoma rangeli stocks were isolated from naturally infected mammals and triatomine vectors. twenty-two stocks were from the common opossum (didelphis marsupialis), one from the brown "4-eyed" opossum (metachirus nudicaudatus), one from the anteater (tamandua tetradactyla), one from the coati (nasua nasua), seven from rhodnius pictipes and 14 from rhodnius robustus. two stocks were also isolated from recently fed sandflies (lutzomyia sp., shannoni group). the stocks were identi ... | 1983 | 6418015 |
| diagnosis of chagas' disease in humans using a biotin-3h-avidin radioimmunoassay. | a radioimmunoassay (ria) originally designed to measure antibody responses to trypanosoma cruzi in mice was adapted for use in the immunodiagnosis of chagas' disease in humans. the assay utilizes biotinylated antibodies and 3h-avidin as the tracer molecules, and has proven to be both safe and sensitive. results using the ria and those from direct agglutination and indirect fluorescent antibody tests were comparable in most cases. using the ria, we were able to discriminate between mice infected ... | 1984 | 6421182 |
| epidemiology of trypanosoma cruzi in the oriental plains of colombia. | epidemiologic studies to define the domiciliary and extradomiciliary transmission cycles of trypanosoma cruzi and trypanosoma rangeli in the oriental plains of colombia were conducted in the gallery forests near carimagua and el porvenir. one-hundred and seven palm trees belonging to nine genera were examined; triatomines were found in only three palm species, the leaves of which are locally used for roof thatching: 2/29 maximiliana elegans, 1/7 mauritia flexuosa and 7/7 scheelea sp. bugs were a ... | 1984 | 6439062 |
| identification of antigens of culture forms of trypanosoma cruzi and trypanosoma rangeli recognized by sera from patients with chronic chagas' disease. | | 1984 | 6439848 |
| studies on trypanosoma rangeli tejera, 1920. iii. direct transmission of trypanosoma rangeli between triatomine bugs. | | 1982 | 6763503 |
| studies on trypanosoma rangeli tejera, 1920. iv--a reconsideration of its systematic position. | | 1982 | 6764519 |
| the effect of lampit on trypanosoma rangeli in experimentally infected mice. | mice experimentally inoculated with metacyclic forms of trypanosoma rangeli were given orally 10, 25, 50 or 100 mg/kg of body weight/day of lampit on 20 consecutive days. the results of combined examinations of fresh blood, giemsa stained blood preparations, blood cultures, blood concentration, repeated xenodiagnosis with rhodnius prolixus and blind passages via triatomine bites to other mice demonstrated that a dose of 50 to 100 mg/kg/day of the drug eliminated t. rangeli from the blood of all ... | 1982 | 6814024 |
| the penetration of the salivary glands of rhodnius prolixus by trypanosoma rangeli. | ultrastructural studies of the mechanism of penetration of the salivary gland of the reduviid bug rhodnius prolixus by trypanosoma rangeli showed that trypanosomes from the haemocoele penetrate the outer "membranes" of the gland flagellum foremost, disrupting the inner layers, to pass between the muscle cells to reach the gland cell basement membrane. this latter is also penetrated flagellum foremost, the parasite invaginating the gland cell plasmalemma beneath, to create a vacuole in which the ... | 1980 | 6994382 |
| early invasion of trypanosoma rangeli into the haemolymph of rhodnius prolixus. | | 1980 | 7001694 |
| detection of trypanosoma rangeli by salivation of infected rhodnius prolixus on glass slides. | | 1980 | 7008724 |
| antigenic differentiation of trypanosoma cruzi and trypanosoma rangeli by means of monoclonal-hybridoma antibodies. | sera from balb/c mice, hyperimmunized with ruptured epimastigotes of either trypanosoma cruzi or trypanosoma rangeli, lacked species-specificity when assayed for antibodies by indirect immunofluorescent microscopy and by the enzyme-linked immunosorbent assay. however, when plasma cells from those mice were fused with syngeneic mouse plasmacytoma cells, many of the resultant hybridomas synthesized antibodies which were species-specific. four clones are synthesizing antibodies specific for antigen ... | 1981 | 7034561 |
| studies by electron microscopy of the giant forms of some african and south american trypanosomes found other than within their mammalian host. | giant multinucleate cyst forms of 3 brucei group trypanosomes and 2 south american species were found in culture systems and within the insect host cells by electron microscopy; the african stocks within the tsetse mid-gut cells, an unidentified brazilian trypanosome within the bug's gut cells and trypanosoma rangeli within the muscle layers surrounding the bug's salivary gland. the various forms found were similar in that they contained varying numbers of large vacuoles, usually lined by subpel ... | 1982 | 7037576 |
| infectivity of trypanosoma rangeli in a promonocytic mammalian cell line. | the existence of an intracellular stage of trypanosoma rangeli in the vertebrate host was evaluated by experimental infection of the u937 histiocytic cell line with the san agustín strain and the ub66-5b clone. the identity of the parasites at the beginning and end of the experiments was confirmed through biological behavior in the vector and mammal hosts, isoenzymes, polymerase chain reaction (pcr), and monoclonal antibodies. infectivity to u937 cells of t. rangeli obtained from culture and sal ... | 1995 | 7472856 |
| genes for cysteine proteinases from trypanosoma rangeli. | pcr amplification of genomic dna from the american trypanosome, trypanosoma rangeli, using as primers oligonucleotides derived from the gene of cruzipain, the major cysteine proteinase (cp) from trypanosoma cruzi, allowed the production of a probe which was used to obtain three clones encoding a cp with 70% overall identity with cruzipain. the genes are organized in tandem, with a monomere size of approximately 2 kbp, located on two chromosomes which, in some parasite isolates, have a high molec ... | 1995 | 7607394 |
| purification and partial characterization of a cysteine proteinase from trypanosoma rangeli. | epimastigotes of the american trypanosome trypanosoma rangeli contain a very low cysteine proteinase (cp) activity. the enzyme was purified to homogeneity by affinity chromatography on cona-sepharose and cystatin-sepharose. this cp had a similar apparent molecular mass and an identical n-terminal sequence (15 amino acids) as compared with cruzipain from trypanosoma cruzi; cross-reacted immunologically with the latter enzyme, it was inhibited by e-64 and tlck, but not by pmsf, o-phenanthroline or ... | 1995 | 7607395 |
| trans-sialidase genes expressed in mammalian forms of trypanosoma cruzi evolved from ancestor genes expressed in insect forms of the parasite. | the trans-sialidase of trypanosoma cruzi mammalian forms transfers sialic acids from host's cell-surface glycoconjugates to acceptor molecules on parasite cell surface. to investigate the mechanism by which the mammalian stages of trypanosoma cruzi have acquired their trans-sialidase, we compared the nucleotide and predicted amino acid sequences of trans-sialidase genes expressed in different developmental stages and strains of trypanosoma cruzi with the sialidase gene of trypanosoma rangeli and ... | 1995 | 7666441 |
| population genetics of trypanosoma cruzi and trypanosoma rangeli: taxonomical and epidemiological purpose. | a genetic analysis of a set of trypanosoma cruzi and trypanosoma rangeli stocks was performed by two combined approaches, namely multilocus enzyme electrophoresis (mlee) and labeling by dna probes. a considerable genetic variability was evidenced within each of the two species. since the upper level of resolution of the isoenzyme method was reached, it was impossible to draw any definite discrimination between the two species by usual clustering methods. nevertheless, two markers appeared as spe ... | 1993 | 7670539 |
| trypanosoma cruzi and trypanosoma rangeli: interplay with hemolymph components of rhodnius prolixus. | studies were carried out on the course of infection of trypanosoma cruzi (clone dm28c) and trypanosoma rangeli (clone san agustin) and their interactions with hemolymph components of rhodnius prolixus. these parasites when inoculated into the hemocoel of adult r. prolixus (i) had different courses of infection (t. rangeli had high rates of both multiplication and infection and t. cruzi had no division and disappeared soon from the hemolymph); (ii) induced high but no differential increases in ly ... | 1995 | 7745280 |
| kinetoplast dna from trypanosoma rangeli contains two distinct classes of minicircles with different size and molecular organization. | trypanosomatids are characterized by the presence of kinetoplast dna (kdna), a peculiar form of mitochondrial dna that consists of several thousand minicircles and a few dozen maxicircles catenated in a network. within a species, the minicircles are known to differ in nucleotide sequence, but are homogeneous in size and always cross-hybridize. in all species of trypanosomatids, kdna minicircles have at least one copy of a conserved 100-200 nucleotide region containing an almost invariant 'univer ... | 1994 | 7870129 |
| trans-sialidase and sialidase activities discriminate between morphologically indistinguishable trypanosomatids. | the expression of trans-sialidase and sialidase activities in the kinetoplastid protozoa was explored as a potential marker to discriminate between the morphologically indistinguishable flagellates isolated from human, insects and vertebrate reservoir hosts. by virtue of the differences observed in the ratios of these enzyme activities, a collection of 52 species and strains comprising the major taxa of these parasites could be separated into four expression types. type-i parasites express compa ... | 1994 | 7925453 |
| comparison of chagasic and non-chagasic myocardiopathies by elisa and immunoblotting with antigens of trypanosoma cruzi and trypanosoma rangeli. | trypanosoma cruzi associated myocardiopathy, or chagas disease, continues to be a serious problem in venezuela, for which there is neither a vaccine nor a cure. in order to learn more about the humoral immune response to trypanosomal antigens, and to try to identify dominant antigens, we used elisa and immunoblotting to study the reactivity of sera from patients with chagasic and non-chagasic myocardiopathies, against surface and secreted proteins from t. cruzi and t. rangeli. both species are f ... | 1994 | 8023751 |