| production of nadph in the mannitol cycle and its relation to polyketide formation in alternaria alternata. | the enzymes mannitol-1-phosphate dehydrogenase, mannitol-1-phosphatase, mannitol dehydrogenase and hexokinase participate in an enzymatic cycle in the fungus alternaria alternata. one turn of the cycle gives the net result: nadh + nadp+ + atp leads to nad+ + nadph + adp + pi. the cycle alone can meet the total need of nadph formation for fat synthesis in the organism. a polyketide producing strain of a. alternata shows a lower mannitol oxidation as well as a lower fat synthesis than a nonproduci ... | 1978 | 28947 |
| primary interaction between antibody and components of alternaria. i. immunology and chemical characteristics of labeled antigens. | components were isolated from alternaria tenuis and its culture filtrate, and were radiolabeled with 123-i. the labeled antigenic components had a high polysaccharide content as determined by staining patterns following electrophoresis in polyacrylamide gels and by inactivation with sodium metaperiodate. a primary binding test was employed to detect and measure serum antibodies to the components from a. tennuis. this procedure was more sensitive in detecting antibodies that bound to antigens tha ... | 1975 | 48526 |
| preferential synthesis of ige reaginic antibodies in rats immunized with alum-adsorbed antigens. | the reaginic antibody response to alum-precipitated ovalbumin (oa) and the dialyzed water-soluble extracts of ragweed (dwsr) and alternaria tenuis (dwst) in several strains of rats appeared to be wholly an ige response. there was no evidence of a heat-stable (igga) antibody to oa, dwsr and dwst in the sera of the rats immunized with these antigens suspended in alum. wistar-furth and lew inbred and hooded outbred rats produced comparable amounts of reaginic antibody after immunization with dwst, ... | 1979 | 87378 |
| studies on alternaria allergens. i. isolation of allergens from alternaria tenuis and alternaria solani. | extracts of alternaria tenuis and alternaria solani were separated into dialyzable (molecular weight less than 10,000) and non-dialyzable forms. the latter was further fractionated by gel filtration through sephadex g-100 followed by ion-exchange chromatography on deae-cellulose. the dialyzable material was fractionated by gel filtration through sephadex g-50. the allergenic activities of the fractions obtained from the a. tenuis extract was measured in vitro by the radioallergosorbent test assa ... | 1979 | 114493 |
| [factors influencing the biosynthesis of beta-galactosidase in alternaria tenuis]. | the effect of ph, carbon sources, and some organic substances on the biosynthesis of beta-galactosidase was studied in alternaria tenuis on a defined medium that had been optimized by the method of mathematical planning of experiments. optimal conditions for the production of the enzyme and its liberation into the cultural broth were maintained by adding 2 per cent soya flour to the medium and 0.1 m phosphate-citrate buffer ph 3.0. the production of the enzyme was increased by 3 to 4 times. the ... | 1975 | 240105 |
| [production and properties of a beta-galactosidase preparation from alternaria tenuis]. | different methods of the preparation of fungal beta-galactosidase from the 72-hour culture of alternaria tenuis were tested: lyophilization of the culture liquid, precipitation with ethanol, acetone, ammonium sulphate. optimal results were obtained with precipitation by 1.5 acetone volume. studies of the properties of fungal beta-galactosidase demonstrated that the preparation retained its activity during 22 month storage at 5 degrees c. the fungal preparation had ph optimum at a more acidic zon ... | 1975 | 241996 |
| alternaria alternata as a cause of opportunistic fungal infections in man. | | 1978 | 285458 |
| detection of mutagens produced by fungi with the salmonella typhimurium assay. | forty-one fungal isolates (one isolate per species) representing common plant pathogens and food crop contaminants were grown on sterile, polished rice and assayed for mutagenic activity in the salmonella typhimurium-microsome system. initially, single doses of aqueous and chloroform extracts of the moldy rice were assayed against the ta100 tester strain by incorporating extracts into the growth medium and by applying small quantities on disks placed on the agar surface. suspected activity was e ... | 1978 | 354528 |
| toxins of molds from decaying tomato fruit. | among 27 mold isolates from decaying tomatoes, culture filtrates or ethyl acetate extracts of 8 isolates grown in yeast extract-sucrose medium were markedly toxic (mortality, greater than 50%) to brine shrimp larvae. the toxicity of six of these isolates could be attributed to the presence of citrinin, tenuazonic acid, or t-2 toxin. ethyl acetate extracts of five alternaria isolates and one fusarium isolate were mutagenic for salmonella typhimurium strains. in ripe tomatoes inoculated with toxin ... | 1979 | 391152 |
| [optimization of the conditions for beta-galactosidase biosynthesis in eukaryotes]. | liquid whey can be subsituted by dry whey in the growth medium for saccharomyces fragilis producing endocellular beta-galactosidase. the total biosynthesis of beta-galactosidase by the yeast on the medium containing dry whey can be increased by 40-50 percent as a result of additional stepwise introduction of lactose into the medium or optimization of the medium by mathematical planning of the experiment. constructive metabolism of the yeast is not correlated with the rate of biosynthesis of beta ... | 1978 | 418313 |
| blue light inhibits mycotoxin production and increases total lipids and pigmentation in alternaria alternata. | light inhibits production of the mycotoxins alternariol and alternariol monomethyl ether, both polyketids produced by alternaria alternata. this effect seems to be general because seven isolates of a. alternata with different alternariol- and alternariol monomethyl ether-producing abilities all respond to continuous light with reduced levels of alternariol and alternariol monomethyl ether when the mycotoxins were calculated on a microgram-per-milligram (dry weight) basis. blue light inhibited al ... | 1979 | 526015 |
| metabolites of alternaria alternata: ergosterol and ergosta-4,6,8(14),22-tetraen-3-one. | | 1977 | 560401 |
| tenuazonic acid production by alternaria alternata and alternaria tenuissima isolated from cotton. | cultures of alternaria alternata (three isolates) and alternaria tenuissima (three isolates) obtained from cottonseeds and bolls were toxigenic when cultured on various laboratory media. a mycotoxin was isolated and identified as tenuazonic acid by using solvent partition, thin-layer chromatography, and instrument analyses. toxicity was monitored with brine shrimp and chicken embryo bioassays. all cultures except a. alternata 938 produced tenuazonic acid when grown on cottonseed and on yeast ext ... | 1977 | 562128 |
| light inhibits the production of alternariol and alternariol monomethyl ether in alternaria alternata. | alternaria alternata (fr.) keissler, grown in drop culture, produced alternariol and alternariol monomethyl ether in late growth phase. production was almost completely inhibited when the fungal cultures were exposed to white light (180 w/m2), although mycelial dry weight was not significantly affected. the fungus was most sensitive to light during the exponential growth phase. twelve hours of light exposure was sufficient to decrease significantly the production of the secondary metabolites. in ... | 1978 | 569466 |
| [studies on habitat of fungi on glass fibre wallpaper (author's transl)]. | the fungi strains alternaria tenuis c.g. ness and ulocladium alternariae (cke.) simmons could be isolated from black coloured glass fibre wallpaper. it was investigated that glass fibre wallpaper and covering pastes were not substrate medium but were settled by fungi when there were nutrition substances under or in the air volume of the wallpaper. both isolated fungi strains converted carboxymethyl-cellulose as alone c- and energy source. the fungicide smotilon am limited the spore germination g ... | 1979 | 573036 |
| air-borne fungi in the air of barcelona (spain). ii. the genus alternaria. | the genus alternaria nees formed one of the more important components of the fungus population of the air at barcelone (spain), during a two-year study, from february 1976 through january 1978. results were based only on studied of colonies obtained by gravity-exposed plates. the occurrence of this genus was greatly affected by climatic conditions. in general. however, alternaria appeared to prefer warmer weather. a total of six species of alternaria was identified, of which, alternaria alternat ... | 1979 | 575195 |
| fungal antigens as a source of sensitization and respiratory disease in scottish maltworkers. | mycological and serological studies were carried out as part of a survey of respiratory disease in scottish maltworkers. 70% of stained sputum smears from 574 workers showed the presence of higher plant cells and/or myclelia, and the spores of common environmental fungi. penicillium spp. (90%), rhizopus stolonifer (48%) and yeasts (53%) were the dominant fungi in 699 sputum cultures, and showed a similar proportional distribution in 327 samples of grain, malt, culms and dusts from fifty-six malt ... | 1977 | 589785 |
| molds on vegetables at the time of harvest. | the mean numbers of colony-forming units of molds present on vegetables at the time of harvest were in the range of 4.2 x 10(3) to 6.7 x 10(3)/g for all vegetables except cucurbits and asparagus. the numbers were not influenced by cultivars within species, duration of the growing season, distant separation of the growing fields, or elevation above ground. numbers increased with rainfall during either of 3 days before harvest and decreased when the mean daily temperature exceeded 24 degrees c. th ... | 1978 | 646353 |
| the influence of water-logging stage upon the paddy soil mycoflora in the ukraine. | the soil fungal flora of paddy soils from the southern districts of the ukraine was investigated. from 287 soil samples 170 species were isolated. they belonged to the following genera: oomycetes 1.2%, zygomycetes 8.8%, ascomycetes 5.8%, deuteromycetes 84.2%. certain fungi were found to be dominant forms, among them mortierella alpina peyron., penicillium funiculosum thom, p. rugulosum thom, p. chrysogenum thom, acremonium strictum w. gams, acr. breve w. gams, alternaria alternata (fr.) riessler ... | 1978 | 726714 |
| equine nodular dermatitis associated with alternaria tenuis infection. | | 1978 | 751314 |
| effect of substrate on metabolite production of alternaria alternata. | alternariol and alternariol monomethyl ether are commonly associated with weathered grain sorghum. production of these metabolites and altenuene by isolates of alternaria alternata was evaluated on various sterile grain substrates. at 35% moisture content and 25 c, metabolite yields were highest on rice, intermediate on sorghums, and lowest on wheat and yellow corn. fourteen-to 21-day cultures on milled rice were best in terms of ease of metabolite recovery, even though yields were higher on 28- ... | 1976 | 945039 |
| regulation and metabolic background of polyketide formation. i. effects of (-)-hydroxycitrate and metabolic roles of citrate and malate in fatty acid and polyketide formations. | the effects of (-)-hydroxycitrate on fatty acid and alternariol syntheses from glucose and acetate in alternaria alternata were investigated. fatty acid synthesis from glucose and acetate was inhibited by (-)-hydroxycitrate. the inhibition could partly be removed by the addition of malate or isocitrate. alternariol synthesis from glucose was also inhibited by (-)-hydroxycitrate. this inhibition was not influenced to the same extent by malate addition as was that of fatty acid synthesis. it is sh ... | 1976 | 945650 |
| variability of alternaria alternata: biochemical and immunological characteristics of culture filtrates from seven isolates. | biochemical variability of culture filtrates from the common allergenic mold alternaria alternata was studied. differences between culture filtrates from 7 different isolates and between 4 batches of culture filtrate from the same isolate were observed, suggesting the unreliability of presently employed biochemical methods in the routine standardization of mold allergens and the possibility of difficulties in developing standard techniques for their purification. dextranases, cellulases, and aga ... | 1976 | 985835 |
| nuclear distribution in alternaria tenuis. | nuclear distribution and behaviour during vegetative growth and spore formation in alternaria tenuis was studied utilising the hc1-giemsa staining technique. the vegetative mycelium and conidia are predominantly monokaryotic. anastomoses, followed by nuclear migrations, have been recorded. intercellular nuclear migrations have only been observed in germinating conidia. nuclear behaviour during conidial formation indicates that the conidia are homokaryotic. cytological differences have been found ... | 1976 | 987535 |
| cutaneous microabscess formation from alernaria alternata. | a 69-year-old farmer with acute lymphocytic lymphoma developed multiple ulcerated hemorrhagic cutaneous lesions. alternaria alternata was cultured from the lesions and hyphae were seen in biopsies of the lesions. the potential role of alternaria as a human pathogen is discussed. | 1976 | 989259 |
| primary interaction between antibody and components of alternaria. ii. antibodies in sera from normal, allergic, and immunoglobulin-deficient children. | antibodies in sera from normal, allergic, and immunoglobulin-deficient children were studied for binding to radiolabeled components of alternaria tenuis. significant binding levels were found in 103 of 105 sera from normal children. the levels were age-dependent, rising from a low point in the 7- to 12-month age group to adult levels by the age of 8 years. levels of binding to two antigens, a culture filtrate derivative (125i-clf) and a mycelial derivative (125-i-hs), were similar. sera from ast ... | 1975 | 1094055 |
| effects of tentoxin on enzymic activities in cucumber and cabbage cotyledons. | tentoxin, produced by alternaria alternata (fr.) keissl. causes severe variegated chlorosis in germinating seedlings of certain dicotyledonous species. however, it does not impair radicle and hypocotyl elongation or cotyledon expansion. effects of the toxin on the activity of selected enzymes from both chloroplasts and cytoplasm were determined. cucumber (cucumis sativus l.), which is highly sensitive to tentoxin and cabbage (brassica oleracea l.), which is resistant, were used as test plants. t ... | 1975 | 1171367 |
| incidence of serum precipitins against organic-dust antigens in different populations by counterimmunoelectrophoresis. | the incidence of serum antidust and antifungal precipitins was determined by counterimmunoelectrophoresis in 317 atopic and nonatopic subjects of three geographic areas (north central, southern, and western united states). the selected lyophilized crude antigens employed were from house dust, micropolyspora faeni, candida albicans, alternaria tenuis, aspergillus fumigatus, puccinia coronata, cantharellus cibarius, and amborsia trifida. antidust precipitins were detected with high frequency in at ... | 1975 | 1192851 |
| the atmospheric fungal flora of the athens metropolitan area. | in the research programme of the department of microbiology of the athens university the nature of the mycological flora of the athenian air was studied. the research took place during the calendar year 1971. the open air was sampled twice weekly from two observation stations. the open plate technique was used, petri dishes containing sabourand's agar being exposed for 15 minutes. a total of 180 plates were exposed, and 1714 fungal colonies were isolated; these were subcultured and identified as ... | 1975 | 1207717 |
| dual infection of a white-tailed deer by dermatophilus congolensis and alternaria alternata. | infection by both dermatophilus congolensis and alternaria alternata was found in a 5 1/2-year-old, female white-tailed deer (odocoileus virginianus). encrusted lesions characteristic of dermatophilosis were observed on the hocks, flanks, and back. giemsa-staining of smears of material from beneath the crusts revealed branching filaments, transversely and longitudinally divided into packets of coccoid cells typical of d congolensis. hyphae morphologically consistent with those of a alternata wer ... | 1975 | 1236841 |
| linear, non-mitochondrial plasmids of alternaria alternata. | three plasmids, with sizes of 7.0 kbp, 6.8 kbp, and 5.0 kbp and designated paal-1, paal-2 and paal-3 respectively, have been found in a tentoxin-producing isolate of alternaria alternata. exonuclease digestions show these plasmids to be linear with blocked 5' ends. plasmid paal-1 does not hybridize to nuclear dna, mitochondrial dna, or double-stranded rna from a mycovirus found in the isolate, but does hybridize weakly to a series of linear dnas which are not visible on gels and may include paal ... | 1992 | 1314706 |
| effects of culture media on the in vitro susceptibility of selected opportunistic fungi to fluconazole and itraconazole. | the sensitivity of 23 isolates of opportunistic fungi, aspergillus fumigatus (5), a. flavus (5), a. niger (5), pseudallescheria boydii (5), alternaria alternata (2) and xylohypha bantiana (1), was investigated against fluconazole and itraconazole, using sabouraud's dextrose broth (sd) and a high-resolution (hr) medium (pfizer, inc.). the procedure followed was a standard tube dilution (1 ml/tube) method. candida albicans y01 09 was included as reference strain to monitor quality and reproducibil ... | 1992 | 1324830 |
| saprophytic and keratinophilic fungi isolated from desert and cultivated soils continuously exposed to cement dust particles in egypt. | forty soil samples collected from desert (uncultivated) and cultivated soils, exposed continuously to cement dust were screened for their content of saprophytic and keratinophilic fungi using the hair baiting technique and the dilution plate method. using the hair baiting technique, 21 genera and 31 species were collected from 20 samples of each of desert (15 genera and 21 species) and cultivated (17 genera and 24 species) soils, on sabouraud's dextrose agar. these included chrysosporium keratin ... | 1992 | 1325092 |
| study of mold allergy in asthmatic children in hungary. | we studied the change in sensitivity to propagating aerogenic fungi (spores, conidia) in extrinsic asthmatic children living in an urban environment from 1977 to 1988. according to the skin test, 10.6% of those examined in 1977 were sensitive to the fungi, the proportion being 30.4% in 1985 and 38.5% in 1987/88. the increase may be explained by the increasing frequency of sensitivity to alternaria alternata and phoma betae. in skin tests with bencard allergens, reaction to both types was frequen ... | 1992 | 1342888 |
| [fungi isolated from diseased medicinal plants]. | one hundred and forty-four fungal isolates were obtained from diseased paeonia albiflora pall. var. trichocarpa bung., astragalus membranaceus bung., lithospermum erythrorhizon sieb. et zucc., ledebouriella seseloides wolff and bupleurum falcatum l. which were collected in the test field of tsukuba medicinal plant research station, national institute of hygienic sciences. most of them were identified into 15 genera containing 8 species. fungal species presumed to be pathogens of the host plants ... | 1992 | 1364438 |
| the major allergen content of allergenic preparations reflect their biological activity. | the content of major allergens in biologically standardized allergenic preparations of birch, mite (der p), cat, alternaria (alt a) and ragweed (amb e) was determined. it was found fairly constant between species, i.e. varied within a factor of 2, with the exception of alt a 1 in alternaria alternata extract. this variation is allowed by authorities between different batches prepared from the same species of allergen. the method for biological standardization (bs) prescribed in the nordic guidel ... | 1992 | 1456414 |
| increased prevalence of igg-induced sensitization and hypersensitivity pneumonitis (humidifier lung) in nonsmokers exposed to aerosols of a contaminated air conditioner. | specific igg antibodies against antigens of a contaminated air conditioner were estimated in serum of 134 workers of a printing company. altogether 64% of the workers investigated revealed significantly elevated levels (> 3 u/ml) of igg antibodies specific to these antigens as compared to a nonexposed control group. the occurrence of igg antibodies for microbial extracts were 25% for fusarium, 23% for penicillium notatum, 13% for alternaria tenuis, 12% for aureobasidium pullulans, 9% for sphaero ... | 1992 | 1485005 |
| etiological role of alternaria alternata in human esophageal cancer. | in this paper, the mutagenicity and carcinogenicity of alternariol monomethyl ether (ame), alternariol (aoh), and their relevance to the etiology of human esophageal cancer were studied. these mycotoxins were produced by alternaria alternata which was the main contaminating fungi isolated from the grain in linxian county, an area with high incidence of esophageal cancer. this study demonstrated that: 1. ame and aoh might cause cell mutagenicity and transformation; 2. ame and aoh could combine wi ... | 1992 | 1499370 |
| aal toxins, fumonisins (biology and chemistry) and host-specificity concepts. | the aal toxins and the fumonisins (fb1 and fb2) are structurally related and produced respectively by alternaria alternata f.sp. lycopersici and fusarium moniliforme. aal toxin is characterized as a host-specific toxin, toxic to tomato, whereas fumonisin b1 causes equine leukoencephalomalacia. fb1 and fb2 were biologically active in susceptible tomato tissue (earlypak-7) and animal tissue culture (rat hepatoma h4tg and dog kidney mdck). conversely, aal toxin was also active in the rat and dog ti ... | 1992 | 1513374 |
| antifungal potential of binary and mixed-ligand complexes of n,2'-diphenyl acetohydroxamic acid. | chelating potential of n,2'-dpaha with 3d metal ions such as cu(ii), ni(ii), zn(ii), and cd(ii) in the presence of gly and phen has been investigated. these experiments were designed to study the role of the stability of mixed-ligand complexes in the modulation of its fungicidal potential. the mixed-ligand complexes were found to be more stable than binary complexes. enhanced stability of mixed-ligand complexes of ni(ii), co(ii), zn(ii), and cd(ii) is presumably due to pi-bonding effects. in the ... | 1992 | 1517732 |
| evaluation of filamentous fungi isolated from petals of bean and rapeseed for suppression of white mold. | the influence of filamentous fungi isolated from petals of bean and rapeseed on white mold caused by sclerotinia sclerotiorum was evaluated. in laboratory trials, macerates of agar plugs containing hyphal fragments of the pathogen in combination with individual fungi were applied onto celery petioles, and subsequent lesion diameters were recorded. the efficacy of 10 fungi exhibiting a spectrum of lesion suppression on celery was correlated with the efficacy of the same fungi in growth-room (r = ... | 1992 | 1521186 |
| ligational behavior of n-substituted acid hydrazides towards transition metals and potentiation of their microbiocidal activity. | new complexes of cu(ii), ni(ii), and co(ii) with 3-benzoyl-1-[2-n-(substituted-2'-thienyl methylmethylene/methylene)] prop-2-ene-1-oic acid hydrazides have been synthesized and characterized by elemental analysis, molecular weight determination, molar conductance, and magnetic moment and spectroscopic techniques. conductance measurements indicate the nonionic nature of the complexes. from the spectroscopic studies, it has been concluded that the n-substituted acid hydrazides act as tridentate li ... | 1992 | 1522414 |
| study on the pathogenic factors of kashin-beck disease. | kashin-beck disease (kbd) is a chronic osteoarthritic disease, endemic in parts of china. its etiology is unknown. selenium deficiency, high concentration of organic matter (mainly fulvic acid) in drinking water, and severe contamination of grain by fungi have been proposed environmental causes. free radicals, possible mediators between the environmental factors and origin of kbd, have been studied in this work. drinking water from kbd-affected areas contains a higher level of semiquinone radica ... | 1992 | 1542136 |
| viability of fungal cultures maintained at -70 degrees c. | one thousand four hundred forty-seven clinical and environmental isolates of molds, yeasts, aerobic actinomycetes, and algae belonging to 164 genera (382 taxa) maintained on potato dextrose agar at -70 degrees c for periods ranging from 6 months to 13 years were subcultured and then incubated at 25 degrees c to determine their viabilities. thirty-three isolates, alternaria alternata (n = 1), apophysomyces elegans (n = 1), bipolaris spicifera (n = 1), blastomyces dermatitidis (n = 4), cokeromyces ... | 1992 | 1572955 |
| inhibition of polyketide synthesis in alternaria alternata by the fatty acid synthesis inhibitor cerulenin. | the fatty acid synthase inhibitor cerulenin (50 to 100 micrograms/ml) inhibited production of the polyketide mycotoxins alternariol (aoh) and alternariol monomethyl ether (ame) by the mold alternaria alternata. the results suggested that aoh synthesis was inhibited by a direct mechanism by cerulenin, whereas production of ame was probably limited by a shortage of the precursor aoh. | 1992 | 1575478 |
| [toxin-producing ability of molds of the genus alternaria]. | the ability to produce the alternaria mycotoxins alternariol (aoh), alternariol monomethyl ether (ame) and altenuene (alt) were studied on 87 alternaria strains. 50 isolates were studied to produce tenuazonic acid (tea). the strains were isolated from ccm-maize and stored hay. they were cultured under optimum conditions and analysed by various chromatographic methods for the 4 mycotoxins. all alternaria strains studied produced ame and tea, 77 per cent also aoh. a production of alt was detected ... | 1992 | 1609553 |
| synthesis, characterization, and microbiocidal activity of alpha-methyl-(2-thiophenomethylene) aryloxyacetic acid hydrazides and their metal complexes. | complexes of alpha-methyl-(2-thiophenomethylene) aryloxyacetic acid hydrazides with cu(ii) and zn(ii) metal salts were synthesized and characterized by elemental analysis, molecular weight determination, molar conductance, and magnetic moment and spectroscopic techniques. in these complexes, the ligands form a conjugate o-n-s tridenate system, thus coordinating with metal through oxygen of the carbonyl group, nitrogen of azomethine, and sulphur of thiophenemoiety. octahedral geometry is proposed ... | 1992 | 1619403 |
| effect of mitotane on alternaria alternata infection in cushing's syndrome. | | 1991 | 1670675 |
| keratinophilic fungi and other moulds associated with air-dust particles from egypt. | one-hundred and eleven species and three species varieties belonging to 39 genera were collected from 50 dust samples on the five media used at 28 degrees c. using the hair-baiting technique with horse hair, 10 species of chrysosporium were isolated: c. asperatum, c. state of arthroderma tuberculatum, c. indicum, c. inops, c. keratinophilum, c. merdarium, c. pannorum, c. queenslandicum, c. tropicum and c. xerophilum. true dermatophytes were isolated: trichophyton verrucosum and trichophyton sp. ... | 1990 | 1702081 |
| influence of selenium on the efficiency of fungicide action against certain fungi. | aspergillus funiculosus was isolated from rotted banana fruits, whereas alternaria tenuis and fusarium sp. were isolated from rotted tomato fruits. the isolated fungi tolerated relatively high levels of the fungicide, dithane, up to 2560 ppm on solid medium, but grew well at 40 ppm when supplemented with liquid medium. they are able to tolerate selenite up to 2% (w/v) sodium selenite. a. funiculosus showed no growth in the presence of mixture of 2.5 ppm selenium and 20 ppm dithane, whereas fusar ... | 1991 | 1711889 |
| comparison of skin testing and three in vitro assays for specific ige in the clinical evaluation of immediate hypersensitivity. | a new assay, pharmacia cap system (pcs), for allergen-specific ige (sige) was evaluated in 198 new patients presenting with respiratory symptoms to an urban allergy practice. an experienced allergist examined each patient and clinically assessed sensitivity to timothy, short ragweed, alternaria tenuis, cat, or d. farinae. puncture and selected intracutaneous skin tests (st) with these inhalant extracts were then performed. the physician again rated the likelihood of clinical sensitivity to each ... | 1992 | 1736718 |
| sensitivity to common allergens: relation to respiratory symptoms and bronchial hyper-responsiveness in children from three different climatic areas of australia. | in order to examine further the relation between atopy, as defined by skin-prick tests, and respiratory illness, we studied three populations of schoolchildren aged 8-11 years and living in different climatic areas of new south wales, australia. skin-prick tests were performed using 13 commercial allergen extracts. respiratory and allergic symptoms were assessed using a self-administered questionnaire to parents and bronchial hyper-responsiveness (bhr) was measured by histamine inhalation test. ... | 1991 | 1742649 |
| the 31 kd major allergen, alt a i1563, of alternaria alternata. | a component of alternaria extract, previously identified as the major allergen, alt a i1563, was purified to homogeneity from alternaria mycelium by means of acetone precipitation and ion-exchange chromatography. the homogeneity of alt a i1563 was assessed by one single band after sodium dodecyl sulfate-polyacrylamide gel electrophoresis, by one single radiolabeled band after transfer to nitrocellulose, and by one single peak after size-exclusion chromatography by high-performance liquid chromat ... | 1991 | 1744361 |
| [alternaria infestation of corn silage and hay]. | the numbers of fungi and the portions of alternaria species in silage maize before harvesting and in hay stored were determined. alternaria is present in growing maize with 18.3 percent of the total numbers of fungi. it occurs mainly on leaves and husks. fungi of the genus alternaria also were found in hay, that has been stored for 8 months when total numbers of fungi have been decreased slowly. more than 80 percent of all alternaria strains isolated were determined systematically as alternaria ... | 1991 | 1767605 |
| toxicity of the mycotoxins fumonisins b1 and b2 and alternaria alternata f. sp. lycopersici toxin (aal) in cultured mammalian cells. | fumonisins b1 and b2 and aal toxin are a series of structurally related mycotoxins. fumonisins b1 and b2, produced by fusarium moniliforme sheldon induce toxic hepatitis and hepatomas in rats and leukoencephalomalacia in horses. the cancer-promotion assay which has been used to guide their purification is slow and consumes large amounts of sample. we have examined a series of cultured mammalian cell lines in order to develop a more rapid and sensitive bioassay system, which may be useful for exa ... | 1991 | 1780003 |
| mutagenicity of alternaria alternata and penicillium cyclopium isolated from grains in an area of high incidence of oesophageal cancer--linxian, china. | in order to study the relationship between daily consumption of mouldy food and the incidence of oesophageal cancer, we examined the mutagenicity of alternaria alternata and penicillium cyclopium, which seriously contaminate grain in linxian county, china. we first examined extracts of cultured strains of a. alternata. in the reverse mutation test, positive results were obtained in 85% of strains; positive results were seen in 84% of 19/20 strains in the rec assay. eight of ten strains induced s ... | 1991 | 1855863 |
| relationships between alternaria alternata and oesophageal cancer. | although it is uncertain whether fungi can produce the mycotoxins that induce oesophageal cancer, the tumorigenicity of fungi isolated from grain in an area of high incidence of oesophageal cancer has been confirmed. alternaria alternata is a fungus of importance in this respect. the contamination rate with a. alternata in corn from areas of high morbidity from oesophageal cancer is higher than that in low-morbidity areas. extracts of a. alternata induced reverse mutation in escherichia coli, un ... | 1991 | 1855864 |
| effect of surface sterilization, fumigation and gamma irradiation on the microflora and germination of barley seeds. | sodium hypochlorite (naocl) and mercuric chloride (hgcl2) surface sterilization, methyl bromide and propylene oxide fumigation and gamma irradiation treatments were compared for their effectiveness in killing microorganisms on or within barley seeds. surface sterilization with 12.5, 25 or 50% (v/v) naocl for 5, 15 or 30 min, decreased fusarium spp., epicoccum purpurascens, and bacillus spp. but did not kill alternaria alternata. however, surface sterilization with 0.1 or 0.2% (w/v) hgcl2 for 3 m ... | 1991 | 1863528 |
| reversed-phase high-performance liquid chromatography of tenuazonic acid and related tetramic acids. | a reversed-phase high-performance liquid chromatographic system for the determination of the fungal toxin, tenuazonic acid, (5s,8s)-3-acetyl-5-sec.-butyltetramic acid, is described. the system utilizes a column packed with deactivated end-capped c18 silica with a high carbon load to overcome the problem of poor chromatographic performance of this beta-diketone on reversed-phase liquid chromatography which previously necessitated the use of anion-exchange, ligand-exchange or ion-pairing methods. ... | 1991 | 1885712 |
| effect of gamma irradiation and water activity on mycotoxin production of alternaria in tomato paste and juice. | gamma-irradiation, water activity (aw) and incubation temperature were found to affect the production of tenuazonic acid (tza) by alternaria alternata in tomato paste and juice. by increasing the irradiation doses, the dry weight as well as tza decreased greatly until complete inhibition at 4 kgy. greatest production of tza occurred at 0.98 aw (57.5 micrograms/g and 26.3 micrograms/g) for both tomato paste and juice, respectively, at 25 degrees c. changing temperature and aw altered the relative ... | 1991 | 1922270 |
| response of long-running alternaria alternata infection to fluconazole. | | 1990 | 1975025 |
| exposure to an aeroallergen as a possible precipitating factor in respiratory arrest in young patients with asthma. | exposure to airborne spores of the common mold alternaria alternata has been implicated in asthma attacks. such exposure is particularly frequent in the midwest during the summer and fall months. to determine the role of a. alternata in triggering severe asthma attacks, we investigated the cases of 11 patients with asthma who had sudden respiratory arrest and determined the frequency of sensitivity to this allergen in these patients. | 1991 | 1987459 |
| chronic alternaria alternata endophthalmitis following intraocular lens implantation. | | 1991 | 1993023 |
| clustering of fungal allergen-specific ige antibody responses in allergic subjects. | statistical analysis of specific ige immune responses to a panel of nine allergens from 2,094 patients demonstrated significant clustering between aspergillus fumigatus, alternaria alternata, and cladosporium herbarum, not explained by crossreactive elements. this may represent a linked, high responder status to these fungal antigens in the allergic population. | 1991 | 1994786 |
| methodological considerations when using nitrocellulose immunoblotting from polyacrylamide gels to study the mould allergens aspergillus fumigatus and alternaria alternata. | the effects of sample treatments, separation conditions, and the possible presence of antibody interference phenomena in sodium dodecyl sulphate polyacrylamide gel electrophoresis (sds page) followed by nitrocellulose immunoblotting (ib) were studied using allergens from alternaria alternata (alt.a.) and aspergillus fumigatus (asp.f.) as model systems. in order to obtain good resolution in the ib method the mould allergens were separated in gradient gels under dissociating conditions (sdsgpage) ... | 1991 | 1995716 |
| mutagenicity of stemphyltoxin iii, a metabolite of alternaria alternata. | some common decay organisms of vegetables and ripened fruits are alternaria species. even fruits and vegetables kept under refrigeration can be spoiled by alternaria species because the mold grows at low temperatures. alternaria alternata is commonly found in grain in areas with a high incidence of esophageal cancer. three metabolites, altertoxins i, ii, and iii, have been isolated from a. alternata and have hydroxyperylenequinone structures. although other perylenequinone metabolites such as st ... | 1991 | 2036005 |
| purification and characterisation of a major allergen of alternaria alternata. | a major allergen of alternaria (alt a bd29k) was identified by sds-page and immunoblotting. it was purified by gel-permeation and ion-exchange hplc. the apparent molecular mass was 29,000, with a cysteine linked sub-unit of 15,000 mr. the apparent isoelectric point was 4.2. it was found to be a constituent of the alt i allergen group. | 1991 | 2062321 |
| [studies on the activation of oncogenes by alternariol monomethyl ether in human fetal esophageal epithelium]. | activation of oncogenes in human fetal esophageal epithelium by alternariol monomethyl ether (ame) is reported. ame is a main metabolite of alternaria alternata which is considered to be a dominant pollutant in the harvested grain in linxian county (a high risk area of esophageal cancer). it was found that nih/3t3 cells were transformed via transfection of dna extracted from human fetal esophageal epithelium having been treated with ame in short term in vitro. the transformed cells formed clony ... | 1991 | 2065371 |
| selective determination of altertoxins by high-performance liquid chromatography with electrochemical detection with dual "in-series" electrodes. | a selective method for the determination of altertoxin-i and altertoxin-ii by high-performance liquid chromatography with electrochemical detection is described. altertoxins were separated on a reversed-phase column with methanol-water containing 0.1 m sodium nitrate and 1 mm nitric acid (60:40) as eluent and detected with dual in-series electrodes operating in the "redox" mode (generator electrode +1.0 v, indicator electrode -0.1 v). the method was applied successfully to the determination of s ... | 1991 | 2071690 |
| natural occurrence of alternaria mycotoxins in sorghum and ragi from north bihar, india. | the natural occurrence of major alternaria mycotoxins i.e. alternariol (aoh), alternariol methyl ether (ame), altenuene (alt), altertoxin-1 (atx-1) and tenuazonic acid (ta) has been investigated in sorghum (sorghum vulgare pers.) and ragi (eleusine coracana gaertn.) collected from north bihar. nine out of 20 sorghum samples, and three out of eight ragi samples, were found to be contaminated with one to three alternaria mycotoxins. the toxin elaborating potential of alternaria alternata (fr.) kei ... | 1990 | 2079114 |
| houses and allergic respiratory syndromes. | a study was carried out in 49 flats in bucharest inhabited by 265 persons. a quantitative analysis of fungi spores was performed as well as allergologic tests with penicillium and aspergillus fungi (a13), aspergillus niger (m2), alternaria tenuis (m1), cladosporium herbarum (m3), dermatophagoides pteronissinus (allergenic products supplied by the bencard firm). the infested flats presented a high percentage of aspergillus niger spores, particularly pathogenic. the main triggering factors for the ... | 1990 | 2100879 |
| alternaria infection in a patient receiving chemotherapy for lymphoma. | a 60-year-old man receiving chemotherapy for an intermediate-grade non-hodgkin's lymphoma developed multiple papuloerythematous cutaneous lesions. alternaria alternata was cultured from the lesions, and hyphae were seen in biopsy specimens. this is an unusual infection, without a well-established treatment, in patients with lymphoma. the use of amphotericin b resulted in cure. | 1990 | 2120894 |
| ungual and cutaneous phaeohyphomycosis caused by alternaria alternata and alternaria chlamydospora. | two cases of ungual and cutaneous phaeohyphomycosis caused by alternaria alternata and alternaria chlamydospora are described. oxiconazole and amorolfine were most effective in vitro against a. alternata and a. chlamydospora respectively. this is the first report of a. chlamydospora as an opportunistic pathogen of skin. | 1990 | 2148601 |
| efficient integrative transformation of the phytopathogenic fungus alternaria alternata mediated by the repetitive rdna sequences. | an attempt was made to transform alternaria alternata protoplasts using a plasmid vector, pdh25, bearing the escherichia coli hygromycin b (hy) phosphotransferase gene (hph) under the control of the aspergillus nidulans trpc promoter. transformants arose on a selective medium containing 100 micrograms hy/ml. there were two types of transformants, forming large and small colonies on the selective medium. transformation with one microgram of the vector produced an average of 4.5 large colonies and ... | 1990 | 2169442 |
| pathologic quiz case 2. invasive alternaria alternata. | | 1990 | 2242268 |
| comparison of conidial and mycelial allergens of alternaria alternata. | alternaria allergens, separated by sds polyacrylamide gel electrophoresis and transferred onto a nitrocellulose membrane, were identified using sera from alternaria-allergic patients. 30 alternaria components of spore and mycelium, ranging in molecular weight from more than 150 to 12 kd, bound ige antibodies. 15 were detected by more than 25% of the sera and only 4 (85, 56, 42, 31 kd) by more than 50% of the sera. among these four major allergens, the 56-kd component was present mostly in the sp ... | 1990 | 2246069 |
| evaluation of basidiomycete and deuteromycete (fungi imperfecti) extracts for shared allergenic determinants. | aqueous extracts of select members of the basidiomycetes and deuteromycetes (fungi imperfecti) were evaluated for the presence of shared allergenic determinants using skin prick and radio-allergosorbent test (rast) inhibition. twenty adults with perennial symptoms of rhinitis, with or without asthma, were skin-prick tested with six species of deuteromycetes and seven species of basidomycetes. positive weal-and-flare reactivity to pleurotus ostreatus was associated with alternaria alternata, fusa ... | 1990 | 2253084 |
| fungal flora associated with combine harvester wheat and sorghum dusts from egypt. | 107 species and 8 species varieties belonging to 44 genera were collected from combine harvester wheat and sorghum dusts (35 genera and 91 species + 4 varieties) and from the atmosphere of their hay sites (26 genera and 69 species + 4 varieties) on glucose- and cellulose-czapek's dox agar at 28 degrees c and 45 degrees c. the mycoflora of wheat and sorghum dusts were basically similar on the two types of media and the most common fungi were: alternaria alternata, aspergillus flavus, a. fumigatus ... | 1990 | 2266490 |
| toxin production by alternaria alternata in tomatoes and apples stored under various conditions and quantitation of the toxins by high-performance liquid chromatography. | alternaria alternata strain 8442-3 was inoculated into tomatoes (lycopersicon esculentum mill.) and red delicious cultivar apples (malus domestica borkh.). half of the lots of each fruit were shrink-wrapped in high-density polyethylene film. wrapped and unwrapped fruits were incubated under darkness at 4, 15 and 25 degrees c for up to 5 weeks. a high-performance liquid chromatography method was developed to quantitate tenuazonic acid (tea), alternariol (aoh), alternariol methyl ether (ame), and ... | 1990 | 2282281 |
| [allergenicity of the osmophilic fungus aspergillus restrictus evaluated by skin prick test and radioallergosorbent test]. | recently large amounts of aspergillus restrictus, a species of osmophilic fungi, have been detected in house dust using culture media with low water activity. but little attention has been paid to this fungus as an allergen. in the present study, the authors examined the allergenic activity of a. restrictus by skin prick tests and radioallergosorbent tests (rast) on 94 asthmatic patients (mean age 12.0, range 3-18). aspergillus fumigatus, alternaria alternata and house dust were used for compari ... | 1990 | 2288495 |
| respiratory atopy in rio de janeiro. | an epidemiologic study was conducted in rio de janeiro, brazil, evaluating 1,410 patients with asthma and/or rhinitis. allergy skin testing was performed in 1,219 patients (intradermal and/or multi-test lincoln diagnostics techniques). thirteen different allergens were tested: house dust, dermatophagoides farinae, grasses, alternaria tenuis, hormodendrum hordei, penicillium mix, aspergillus fumigatus, dogs, cats, feathers, fleas, cockroaches, and household insects. the most frequent positive imm ... | 1990 | 2306018 |
| involvement of fungi and bacteria in enhanced and nonenhanced biodegradation of carbendazim and other benzimidazole compounds in soil. | the relationship between chemical structure and the enhancement of microbial degradation of three benzimidazole compounds in soil was determined. preapplication of methyl benzimidazole-2-ylcarbamate (carbendazim or mbc), 2-aminobenzimidazole (2ab), and benzimidazole enhanced their degradation upon repeated application (self-enhanced degradation). mbc and 2ab cross-enhanced the degradation of each of these two compounds, whereas benzimidazole did not enhance the degradation of mbc. thiabendazole ... | 1990 | 2334872 |
| bronchial allergy in cystic fibrosis. | thirty-one patients with cystic fibrosis (cf) were thoroughly evaluated for allergy. this included a clinical history, skin tests with twenty-three allergens and bronchial provocation with inhaled allergens and histamine. the bronchial response was measured by whole body plethysmography. of the patients studied, 40% showed a bronchoconstrictor response to inhaled allergens, despite the fact that none had reported asthma in their clinical history. strong skin test reactions (3+ and 4+) and weak r ... | 1985 | 2414033 |
| fusarium solani: evidence for common antigenic/allergenic determinants with other fungi imperfecti. | aqueous extracts of fusarium solani and other members of the fungi imperfecti were evaluated for the presence of common antigenic/allergenic determinants using skin-prick testing, radio-allergo-sorbent test (rast) inhibition, and immunoelectrophoretic methods. prevalence of skin reactivity in forty-four atopic individuals, tested with commercially available fungal extracts, ranged from 27.3% for alternaria tenuis to 6.8% for penicillium notatum. no specific patterns of reactivity emerged from st ... | 1987 | 2438068 |
| improved in vitro diagnosis of allergy to alternaria tenius and cladosporium herbarum. | to improve the in vitro diagnosis of mould allergy 22 children suffering from allergic asthma caused by alternaria tenius and/or cladosporium herbarum as proven by bronchial provocation test were investigated. partially purified, standardized mould preparations were used in radioallergosorbent test (rast) with conventional and new update mould discs, mould-induced histamine release and immunoblotting. updated rast discs were found to be superior to the old-type discs for the detection of alterna ... | 1987 | 2444126 |
| fungi in two swimming pools in assiut town, egypt. | 50 water samples from 2 public swimming pools were tested for the presence of fungi using the hair baiting technique and plate count methods. sabouraud's-dextrose agar and littman-oxgall agar media were used for isolation of the fungi. of the keratinolytic fungi 8 species were recorded of which three species were dermatophytes (trichophyton terrestre, 14% of the samples; t. mentagrophytes, 10% and microsporum gypseum, 6%). on littman-oxgall agar the following species were recovered: aspergillus ... | 1989 | 2475993 |
| penicillin amidohydrolases in fungal autolysis. | the production of penicillin g and penicillin v amidohydrolases or acylases (e.c.3.5.1.11) was studied during the autolysis of filamentous fungi in a mineral medium, and in the same medium with phenoxyacetic acid as inducer. in all the studied fungi, enzymes showing penicillin g and penicillin v amidohydrolase activities were found. generally, an increase of these activities during fungal autolysis was observed. the presence of phenoxyacetic acid in the medium did not increase these activities. ... | 1989 | 2499747 |
| [reactivity of human lymphocytes to yeast-like and mold fungi]. | the capacity of the allergens of mold fungi (rhizopus nigricans, mucor pusillus, alternaria tenuis, cladosporum herbarum, fusarium oxysporum) and yeast-like fungi (candida albicans) to induce the production of lymphokins by human lymphocytes was studied. all these preparations were active in reactions with lymphocytes obtained from adult donors, but did not activate lymphocytes of newborns (obtained from umbilical blood). in equal doses (10 micrograms/ml) c. albicans allergen was more active tha ... | 1989 | 2500001 |
| comparison of alternaria tenuis extracts prepared from different raw materials. | alternaria extracts, prepared from three different sources under the same conditions, were compared by several biochemical/immunochemical methods. two raw materials (a,g) contained mostly mycelia. the third raw material (c) contained mycelia (35%) and spores (65%). extracts a and g were different in total allergenic potency, antigen/allergen pattern, and in the alt 1 content. extract c was of similar total allergenic potency as extract a but showed a somewhat different antigen/allergen pattern a ... | 1989 | 2596763 |
| aflatoxins in sunflower seeds: influence of alternaria alternata on aflatoxin production by aspergillus parasiticus. | the aim of the present work was to determine the influence of alternaria alternata upon aflatoxin production by aspergillus parasiticus. a mixture of spores of both strains was inoculated in sunflower seeds at 0.90 aw and incubated for 42 days at 28 degrees c +/- 1. the cultures were observed and analyzed every 7 days to determine the infection level of the seeds and the production of aflatoxins. results showed that when the seeds were inoculated only with aspergillus parasiticus, 100% were infe ... | 1989 | 2615799 |
| odor volatiles associated with microflora in damp ventilated and non-ventilated bin-stored bulk wheat. | western hard red spring wheat, stored at 20 and 25% moisture contents for 10 months during 1985-86, was monitored for biotic and abiotic variables in 10 unheated bins in winnipeg, manitoba. the major odor volatiles identified were 3-methyl-1-butanol, 3-octanone and 1-octen-3-ol. the production of these volatiles was associated and correlated with microfloral infection. ventilation, used for cooling and drying of grain, disrupted microfloral growth patterns and production of volatiles. the highes ... | 1989 | 2641886 |
| biological activity of sulphur ylides. i. antimicrobial properties of some new carbonyl stabilized sulphonium ylides. | antimicrobial properties of some new carbonyl stabilized sulphonium ylides have been tested against two bacteria staphylococcus aureus, escherichia coli and two fungi alternaria alternata and curvularia lunata. the potent antifungal activity of these compounds suggest their practical applications in fungicidal formulations and other pharmacological preparations. | 1989 | 2684160 |
| organization of ribosomal rna genes in alternaria alternata japanese pear pathotype, a host-selective ak-toxin-producing fungus. | dna encoding ribosomal rna (rrna) of alternaria alternata japanese pear pathotype has been cloned in lambda replacement vector, lambda fix. restriction endonuclease mapping and southern hybridization with the 18s and 28s rrnas of saccharomyces cerevisiae revealed the a. alternata rdna to be tandemly repeating 8.15-kilobase pair unit. the restriction fragments of the unit were then subcloned in the plasmid vector bluescribe m13- and partially sequenced. the determined sequences were compared with ... | 1989 | 2697467 |
| stemphyltoxin iii from alternaria alternata. | stemphyltoxin iii, (6ar*, 6bs*, 7r*, 8r*)-3,6a, 10-trihydroxy-4,9-dioxo-4,6a,6b,7,8,9-hexahydro-7,8-epoxyperylene, a known metabolite of stemphylium botryosum var. lactucum, has been identified as a mutagenic metabolite of alternaria alternata by spectroscopic studies. the 13c-nmr spectral data, which were not reported previously, are presented. | 1989 | 2746264 |
| didymella exitialis and late summer asthma. | 4 patients in whom didymella exitialis seemed to be an important cause of their asthma were investigated. all 4 patients had immediate skinprick test reactions and specific ige antibody to d exitialis and alternaria alternata. inhalation of a soluble extract of d exitialis provoked immediate asthmatic reactions in these 4, but not in a skin-prick-test-negative volunteer. radioallergosorbent inhibition studies with d exitialis and a alternata showed self and cross inhibition, which suggested shar ... | 1985 | 2860285 |
| nitrogen inhibition of mycotoxin production by alternaria alternata. | alternaria alternata produces the polyketides alternariol (aoh) and alternariol monomethyl ether (ame) during the stationary growth phase. addition of 12 mm nano3 to the cultures before initiation of polyketide production reduced the aoh and ame content to 5 to 10% of that of controls. glutamate and urea also reduced aoh and ame accumulation, whereas increasing the ionic strength did not affect the polyketide content. adding nano3 after polyketide production had started did not inhibit further a ... | 1988 | 2904801 |
| effects of purified altertoxins i, ii, and iii in the metabolic communication v79 system. | purified alternaria alternata altertoxins i, ii, and iii were evaluated for comparative cytotoxicity and ability to inhibit gap junction communication in the chinese hamster lung metabolic cooperation assay. the noncytotoxic test range for each altertoxin was determined for the metabolic communication assays: altertoxin i, 1, 2, 3, 4, 5 micrograms/ml; altertoxin ii, 0.02, 0.008, 0.006, 0.004, 0.002, 0.0008 micrograms/ml; and altertoxin iii, 0.2, 0.1, 0.08, 0.06, 0.04 micrograms/ml. altertoxin ii ... | 1989 | 2913335 |
| mycoflora and mycotoxin-producing fungi of air-dust particles from egypt. | using the dilution-plate method, 27 genera and 64 species were collected from 20 air-dust samples on glucose - (24 genera and 57 species) and cellulose - (21 genera and 45 species) czapek's agar at 28 degrees c. there are basic similarities between the mycoflora of air-dust on the two media and the most prevalent species were aspergillus niger, a. flavus, a. ochraceus, a. terreus, a. versicolor, penicillium chrysogenum, p. funiculosum, alternaria alternata, cladosporium herbarum, fusarium oxyspo ... | 1986 | 2938009 |
| clinical significance of airborne alternaria tenuis-spores: seasonal symptoms, positive skin and bronchial challenge tests with alternaria in subjects with asthma and rhinitis. | | 1987 | 2958315 |
| [skin alternariosis in a patient with nephrotic syndrome]. | a case of cutaneous alternariasis with appeared during the treatment with corticosteroids in a patient having a nephrotic syndrome, is presented. the diagnosis was verified by histological and mycological examination, isolating alternaria alternata. the etiopathogenic mechanisms and the clinical and histological aspects of the lesions are discussed. good results of treatment with ketoconazole and topic ciclopirox are reported. | 1988 | 3073271 |