Publications

TitleAbstractYear
Filter
PMID
Filter
[iatrogenic mycoses with deep visceral localization caused by opportunistic fungi].the new therapeutic methods based on antibiotics, corticosteroids and immunosuppressors and the new medicosurgical techniques (catheters, monitoring in intensive-care units, open-heart surgery) modify the host, favorise the adaptation and introduction f endogenous and exogenous yeast-like fungi and thus create a new pathology characterized by deep visceral or septicemic infections due to yeasts belonging to the genera candida, torulopsis, cryptococcus, trichosporon, rhodotorula, and saccharomyce ...1979573715
diagnostic medium containing inositol, urea, and caffeic acid for selective growth of cryptococcus neoformans.an agar medium containing inositol and urea as sole carbon and nitrogen sources, caffeic acid and ferric citrate as agents for the selective pigmentation of cryptococcus neoformans, gentamicin as a broad-spectrum bacterial antibiotic, and yeast nitrogen base without amino acids and ammonium sulfate (difco) was tested against 137 clinical isolates, 4 survey specimens, and 11 atcc yeast and yeast-like strains. all 28 strains of c. neoformans showed heavy growth and dark brown pigmentation after 36 ...1977334795
disseminated trichosporon capitatum infection in an immunosuppressed host.trichosporon is a frequent cause of superficial mycotic infections but has rarely been associated with invasive disease. a patient undergoing bone marrow transplantation who died from disseminated trichosporon capitatum infection with endocarditis is reported, and the clinical spectrum of human infection caused by fungi of this genus is reviewed. to our knowledge, this is the first reported case of clearly invasive disease caused by this specific organism and emphasizes the expanding spectrum of ...1977332101
the distribution of pyrophosphatidic acid in nature.the occurrence of a novel phospholipid, pyrophosphatidic acid, in the lipid extracts of yeasts (23 species), bacteria (e. coli), algae (chlorella), mammalia (human, rabbit, guinea pig, and mouse), insect (cockroach), fish (carp), mollusc (clam), and spermatophyta (spinach) was investigated. pyrophosphatidic acid was found exclusively in the lipid extracts of several kinds of yeast species, but not in other normal living species (animals, plants, and microorganisms) so far investigated. all of th ...1975175047
[trichosporon capitatum as pathogen of dermatomycoses].three cases of dermatomcycosis are reported, caused by trichosporon capitatum, a yeast-like organism, belonging to genus trichosporon of the cryptococcaceae, which till now was isolated out of dermatological material only in a few cases. one of the lesions, characterized as "leuconychia mycotica", is a problematic task with regard to the treatment, for it is a professional infection in an offset-printer. a glycerol containing fluid for wiping his printing machine was detected as reservoir of yea ...1976136429
trichosporon sepsis and leukemia.trichosporon cutaneum is a fungus known to cause superficial nodules over the distal third of hair shafts, mainly scalp hair, and to produce a clinical entity known as piedra. this superficial mycosis occurs mostly in temperate and tropical regions and is rarely seen in north america. trichosporon cutaneum spesis is described here in a 12-year-old boy with acute lymphocytic leukemia in relapse. to our knowledge this is the first case reported in the literature. emphasis is made of the increasing ...197552400
metabolism of phenol and resorcinol in trichosporon cutaneum.trichosporon cutaneum was grown with phenol or resorcinol as the carbon source. the formation of beta-ketoadipate from phenol, catechol, and resorcinol was shown by a manometric method using antipyrine and also by its isolation and crystallization. metabolism of phenol begins with o-hydroxylation. this is followed by ortho-ring fission, lactonization to muconolactone, and delactonization to beta-ketoadipate. no meta-ring fission could be demonstrated. metabolism of resorcinol begins with o-hydro ...197933145
degradation of 4-hydroxyphenylacetic acid by trichosporon cutaneum.trichosporon cutaneum degraded 4-hydroxyphenylacetic acid to acetoacetic and malic acids. 3.4-dihydroxyphenylacetic acid, an intermediate in the reaction sequence, underwent hydroxylation before the benzene ring was cleaved.197830749
cellulase formation by soil yeasts of the genus trichosporon and by microscopic fungi.the production of celulases by a soil yeast belonging to the genus trichosporon and by microscopic fungi of various systematic groups was studied. the yeast synthesized relatively small amounts of cellulases in contrast to microscopic fungi. the active culture producing cellulases was the fungus trichoderma longibrachiatum 7-26.197826853
the enzymes of ammonia assimilation in trichosporon cutaneum. 1975239097
killer phenomenon in pathogenic yeast.potentially pathogenic yeast strains from four genera, candida, cryptococcus, torulopsis, and trichosporon, were examined for killer activity and sensitivity using saccharomyces and torulopsis strains of known killer status. tests were performed by using a streak method and by concentration of culture fluid by lyophilization. of 236 strains examined, killers were found with low prevalence among torulopsis and cryptococcus strains; candida and trichosporon isolates showed no killing activity. dif ...1979572656
catabolism of l-tyrosine in trichosporon cutaneum.protocatechuic acid was a catabolite in the degradation of l-tyrosine by trichosporon cutaneum. intact cells oxidized to completion various compounds proposed as intermediates in this conversion, but they did not readily oxidize catabolites of the homogentisate and homoprotocatechuate metabolic pathways, which are known to function in other organisms. cell extracts converted tyrosine first to 4-hydroxycinnamic acid and then to 4-hydroxybenzaldehyde and 4-hydroxybenzoic acid. the proposed hydrati ...1979571434
the origin and species of yeasts in commercial preparations of bovine semen.whereas yeasts were not normally isolated from raw semen samples 13% of commercial frozen semen samples and 71% of preputial washings contained yeasts. nine genera and 25 species of yeasts have been identified from these two sources. yeasts originating in the preputial cavity were generally saprobic members of the genera candida, cryptococcus, rhodotorula, saccharomyces, torulopsis and trichosporon. those originating as contaminants during processing were more likely to be opportunistic pathogen ...1979570874
colonization of hospitalized patients with yeast-like organisms.the pharyngeal, fecal and skin carrier rates of yeast-like organisms was determined in 126 patients on the day of admission to a larger veterans administration hospital. none of these patients had been hospitalized or received anti-microbial agents during the previous year candida and torulopsis species were most common. a small percentage of patients were carriers of various species belonging to the genera trichosporon, rhodotorula, saccharomyces, leucosporidium and endomycopsis. fifty of the o ...1977564082
[moulds of bakery dusts (author's transl)].a total of 260 samples from bakery dusts were investigated. the samples were taken in the great part with the sedimentation-method. a large concentration of moulds was found in the meal-room. the fungal flora was here charcterized by species of rhizopus nigricans, mucor and circinella. with a new volumetric sampler a total quantity of 8 680 fungus spores of particles in 1 m3 was registrated. by a re-examination we found 4473. in the baker's rooms besides moulds (aspergillus, penicillium etc.) th ...1977558701
mycotic flora in the lower digestive tract of feral pigeons (columba livia) in the el paso, texas area.fourteen species of fungus were isolated from the lower digestive tract of 39 of 80 pigeons. sixteen pigeons had concurrent isolations while two harbored three species. fungi isolated were allescheria boydii, aspergillus spp., candida krusei, chrysosporium spp., geotrichum candidum, mucor spp., paeciliomyces spp., penicillium spp., rhizopus spp., rhodotorula spp., scopulariopsis spp., streptomyces spp., and trichosporon cutaneum. there was no apparent evidence that these fungi were associated wi ...19761255918
tube carbohydrate assimilation method for the rapid indentification of clinically significant yeasts.yeasts have gained greater recognition in the past several years as being the cause of significant infections. we modified and evaluated a carbohydrate assimilation test to identify yeast isolates rapidly and accurately. the 192 clinical isolates used in this study included 20 species of the genera candida, cryptoccoccus, saccharomyces, torulopsis, trichosporon, rhodotorula, and geotrichum. the method achieved 95% agreement with standard wickerham assimilation results, and 97% of the isolates we ...1978351362
carbohydrate composition and taxonomy of geotrichum, trichosporon and allied genera.the yeast-like genera geotrichum and trichosporon are heterogeneous and are related with anamorphs of both ascomycetous and basidiomycetous fungi. a rearrangement can be obtained using carbohydrate composition of intact cells, studied with the aid of gas-liquid chromatography. the genus geotrichum is restricted to ascomycetous species with a dominance of galactomannans, whereas trichosporon is reserved for basidiomycete-like, xylose-containing species. consequently, some new combinations are int ...1979575971
deoxyribonucleic acid base composition and taxonomy in the genus geotrichum link.the molar percentage of guanine + cytosine (% gc) in the dna from 25 yeast-like fungi related to the genus geotrichum has been measured. this criterion together with the biochemical characteristics allow the division of the species into 3 groups: one group resembling g. candidum (% gc: 31.5--42) and containing 8 imperfect and 6 perfect forms. in this group only g. capitatum has a lower % gc (31.5). a second group of 6 species resembling the genus trichosporon (57--60%) and a third intermediate c ...1979582888
evaluation of the new api 20c strip for yeast identification against a conventional method.the new api 20c yeast identification system together with appropriate microscopic morphology determinations achieved a 97% correlation with a rapid conventional method. whereas a group composed of candida, torulopsis, saccharomyces, and rhodotorula was identified with ease (98% overall correlation), a second group, containing cryptococcus, trichosporon, and geotrichum species, appeared to give the system the most difficulty (90% correlation). within this group particular difficulty was encounter ...1979385621
evaluation of a commercial multitest system for identification of yeasts.a new commercial yeast identification system, the randolph multitest mycology plate, was evaluated. this system is based on the assimilation of carbohydrates, growth on birdseed agar, resistance to cycloheximide, hydrolysis of urea, and reduction of nitrate. the 184 clinical isolates used in the evaluation included 20 species of the genera candida, cryptococcus, saccharomyces, torulopsis, trichosporon, rhodotorula, and geotrichum. agreement with the standard wickerham carbohydrate assimilation a ...1978354378
[microflora of the low-mineralized waters of the truskavets deposit].waters of the truskavetz deposit with a low content of mineral substances were found to contain considerable amounts of microorganisms; upto millions of cells per 1 ml. sulphate-reducing, dentrifying and iron bacteria were detected in the waters. the following genera were represented and isolated: pseudomonas, bacillus, nocardia, arthrobacter, brevibacterium, corynebacterium, micrococcus, candida, cryptococcus, rhodotorula, hansenula, torulopsis, trichosporon. many of the studied strains assimil ...1978672688
in vitro survival of human pathogenic fungi in seawater.the survival of propagules from 4 pathogenic fungi, trichophyton mentagrophytes, trichosporon cutaneum, candida albicans, and microsporum gypseum was studied in seawater subjected to different temperature (20--35 degrees c) and salinity (6--50%) levels in diurnal rhythm of 12 h cycles. survival was measured by viability of propagules over a period of 52 weeks. all fungi, except t. cutaneum at 35 degrees c survived the experimental conditions for 52 weeks. temperature was the most influential fac ...1979375437
evaluation of a caffeic acid-ferric citrate test for rapid identification of cryptococcus neoformans.an evaluation of a rapid caffeic acid-ferric citrate paper disk test for the identification of cryptococcus neoformans, using 474 isolates of yeasts and yeastlike organisms, showed that 96.6, 97.7, and 98.3% of 176 isolates of c. neoformans produced brown to dark-brown pigment on disks incubated for 6 h at room temperature, 30 degrees c, and 37 degrees c, respectively. all c. neoformans produced brown to dark-brown pigment within 24 h. however, nonspecific pigmentation was encountered at all tem ...1977336639
evaluation of a modified dye pour-plate auxanographic method for the rapid identification of clinically significant yeasts. comparison with two commercial systems.a modified dye pour-plate auxanographic (dppa) method for the presumptive identification of medically important yeasts was evaluated, in a comparative study with a conventional procedure, the api 20c clinical yeast system (analytab products inc.), and the uni-yeast-tek (uyt) system. the 174 coded clinical isolates were members of the genera candida, cryptococcus, rhodotorula, saccharomyces, torulopsis, and trichosporon. the identification accuracies with dppa, api, and uyt were 95%, 93%, and 99% ...1979375051
in vitro survival of human pathogenic fungi in hawaiian beach sand.in vitro studies utilizing 4 pathogenic fungi, trichosporon cutaneum, candida albicans, microsporum gypseum and trichophyton mentagrophytes, all known from hawaiian beaches, indicate that they survive in the fluctuating beach habitat where they can serve as potential sources of infection for significant periods of time. survival was measured by testing the viability of propagules at intervals for 6 months. all species survived 6 months under 1 or more experimental conditions. survival patterns s ...1979375438
role of opportunistic fungi in ocular infections in nigeria.the importance of opportunistic fungal pathogens in causing ocular infections is emphasized. a study was conducted over a period of 4 years (1974--1977) to investigate the role of opportunistic fungi in causing mycotic keratitis and to elucidate certain aspects of epidemiology of this disease in nigeria. fifty-nine cases of corneal ulcers of suspected mycotic etiology were investigated. fungal etiology was confirmed in 42 of these cases. the predominant etiological agent was fusarium solani in 1 ...1978745623
[diagnosis of candida albicans mycosis in gynaecology by the germ tube test (author's transl)].experience with the germ tube test for the diagnosis of candida mycosis in gynaecology and dermatology is reported. candida albicans forms germ tubes in human serum and other culture media at 37 degrees c within 2 to 3 hours. if the initial culture grows yeast, the germ tube test permits the exact identification of the yeast as candida albicans within three to five hours. the specificity of the test is approximately 99%. of 3270 samples 934 grew yeast and 742 were candida albicans by the germ tu ...1978342332
phenol hydroxylase from yeast. sulfhydryl groups in phenol hydroxylase from trichosporon cutaneum.thiol groups in phenol hydroxylase were measured using two different -sh reagents and amino acid analysis. stepwise blocking of the -sh groups was correlated with enzyme activity and fad content. the results indicate that the enzyme contains 16 -sh groups per molecule of mr 1.48 x 10(5). at least four -sh groups are not accessible without the use of a denaturing agent. there is seemingly no disulphide bridge. on the whole, the reactivity towards p-hydroxymercuribenzoate is much greater than towa ...1975810352
[recent causal organisms of bacteremia and a case of septicemia caused by trichosporon cutaneum (author's transl)]. 1978101615
mycoses of the sudan.mycoses in the sudan are still significant and, as well as mycetoma, there are a number of fungal diseases: paranasal aspergillus granuloma, which came into eminence in 1966; actinomycosis; subcutaneous phycomycosis; systemic phycomycosis; post-operative opportunistic infection of the eye with trichosporon cutaneum and rhinosporidiosis. mycetoma and paranasal aspergillus granuloma are discussed in detail.1977888164
the morphological identification of pathogenic yeasts using carbohydrate media.eight isolates of c. albicans were used to determine the frequency with which germ tube formation occurred: on rice extract -tween 80 agar, on its components, and on 1% bactopeptone agar after three hr at 37 degrees c; in 0.5% aqueous solution of various carbohydrates; in various concentrations of glucose; on 0.5 and 0.1% glucose agar and on various types of agar alone. subsequently 250 isolates of yeast of the genera candida, torulopsis, trichosporon, cryptococcus, and saccharomyces, which were ...19751091660
xylan-degrading activity in yeasts: growth on xylose, xylan and hemicelluloses.the ability to grow in liquid media with d-xylose, xylan from decidous trees, and hemicelluloses from conifers was tested in 95 strains of 35 genera of yeasts and yeast-like organisms. of 54 strains thriving on xylose, only 13 (genera aureobasidium, cryptococcus and trichosporon) utilized xylan and hemicelluloses as growth substrates. the árowth media of these strains were found to contain xylan-degrading enzymes splitting the substrate to xylose and a mixture of xylose oligosaccharides. the abi ...1978700524
[yeast flora of plant rhizosphere and phyllosphere].the species belonging to the genera cryptococcus and hansenula with saturnian spores predominate in the rhizosphere of agricultural plants. the sporiferous strains of debaryomyces, hanseniaspora apiculata, metschnikowia pulcherrima, and asporogenic candida krusei and trichosporon cutaneum prevail in the rhizosphere of wild plants. candida krusei and trichosporon cutaneum prevail in the rhizosphere of wild plants. the cultures of rhodotorula, candida krusei and metschnikowia pulcherrima are typic ...19751226148
[effect of the chemical nature of the carbon source in the medium on the makeup of the biomass].the yeast candida tropicalis, candida utilis, trichosporon cutaneum were cultivated on the synthetic medium containing additions of group b vitamins (biotin, thiamin) and glucose, glycerol of lactic acid as the sole source. the protein content, amino acid composition, nucleic acids and complex b vitamins were identified in the resultant biomass. the carbon source in the medium affected these indices. the protein and nucleic acid content also depended on the yeast strain.19751237887
[cultivation of the yeast trichosporon cutaneum k-1 on milk serum].yeast trichosporon cutaneoum k-1 were cultivated on milk serum supplemented with nitrogen and phosphorus sources. the culture showed a high biosynthetic capacity. the specific growth rate (mu) of yeast on milk serum was 0.40-0.45 hr-1. during lactose assimilation in the synthetic medium mu was 0.43 hr-1 and the economic coefficent of the biomass yield was 54%. it was shown that assimilation first involved lactose and then organic acids. the composition of the resulting biomass was identified.19751239760
[zinc consumption from the nutrient medium of trichosporon capitatum and aspergillus niger].the sorption capacity of the cultures trichosporon capitatum and aspergillus niger towards zinc dissolved in the culture liquid was studied by radio active labelling. the curves of sorption kinetics and the so-called sorption quasi-isotherms showing the dependence of zinc sorption by the microbial biomass upon zinc concentration in the liquid medium were derived. for the aspergillus niger culture at zinc concentrations of 0.5 to 52 mug/ml the sorption quasi-isotherm was linear. the zinc extracti ...19751239764
in vitro activity of amphotericin b, hamycin and their novel water-soluble compounds against pathogenic yeasts.twenty-eight pathogenic isolates, 4 each of candida albicans, c. lusitaniae, c. parapsilosis, cryptococcus neoformans, torulopsis glabrata and trichosporon beigelii were tested for their in vitro sensitivity to amphotericin b (amb), hamycin (ha) and their novel water-soluble compounds, namely jai-amb (oral and injectable; patents pending) and jai-ha (jaimycin inc., walnut creek, calif., usa), using a standard double-dilution broth (1 ml/tube) procedure. the 2 novel compounds, namely jai-amb and ...19921286573
trichosporon cutaneum endocarditis.a 61-year-old man with trichosporon cutaneum (t. cutaneum) prosthetic valve endocarditis is reported. he had had an aortic valve replacement for rheumatic heart disease 3 years earlier. onset of the valve infection was subacute. a systolic murmur was noted on admission. subsequently, he developed conjunctival hemorrhages, hematuria and transient episodes of confusion, aphasia and cranial nerve palsies. three of 17 blood cultures taken over 3 weeks were positive for t. cutaneum. he was given amph ...1978715385
vaginal yeast flora of pregnant women in the cusco region of peru.a study of the vaginal yeast flora in pregnant women living in cusco and in its region (peru), located approximately 3000 m above sea level, is reported. we observed 300 pregnant, healthy and non-diabetic women who attended a gynaecological clinic in the lorena, regional or ipss (instituto peruano de seguridad social) hospitals in cusco. a comprehensive clinical history was obtained from each patient. it included age, work, parity, time of pregnancy, use of contraceptives or antibiotics, type of ...19921291874
mouse model for disseminated trichosporon beigelii infection. 19921318450
[rare opportunistic fungal diseases in patients with organ or bone marrow transplantation].candidiasis, aspergillosis and cryptococcosis are the most common fungal infections in transplant recipients. however other fungal infections have been reported. mucormycosis, scedosporium infections, fusariosis and trichosporonosis represent the largest part of these rare mycosis. the clinical and mycological features are described here. in addition, cases of very uncommon mycosis, most of them only once reported, have been reviewed. overall the diagnosis is difficult as mycological examination ...19921340094
[trichosporon capitatum septicemia. apropos of 5 cases].invasive trichosporon capitatum infections are seldom reported. we present here five cases of septicemia. all patients had an acute myeloblastic leukemia and were severely neutropenic. they have also been treated before the onset of the fungal infection with broad-spectrum antibiotherapy and also with an oral azole antifungal agent. the role of this antifungal therapy in the development of t. capitatum infection is discussed. the prognosis of t. capitatum infections is severe. eight of the 10 pu ...19921340100
effect of cigarette smoking on prevalence of summer-type hypersensitivity pneumonitis caused by trichosporon cutaneum.we investigated the effect of cigarette smoking on the prevalence of summer-type hypersensitivity pneumonitis (shp) caused by trichosporon cutaneum. in the adult family members of shp patients, we found that 27 of 41 (65.9%) nonsmokers were shp patients, compared with 3 of 11 (27.3%) smokers (p less than .05). also, the prevalence of anti-t. cutaneum antibody was significantly lower in the smokers (p less than .05). a questionnaire provided to 209 shp patients revealed that the smoking rates of ...19921344064
[letter: yeasts isolated from human urinary sample. prevalence and high resistance of trichosporon cutaneum]. 1976785383
yeasts in biodegradation and biodeterioration processes. 19901366489
amperometric determination of ammonium ions with a microbial sensor.a sensor for nh+4 ions has been developed, which consists of immobilized micro-organisms (bacillus subtilis, pseudomonas aeruginosa, trichosporon cutaneum) in combination with an electrochemical transducer. this sensor is based on the measurement of acceleration of respiration after addition of nh+4 in the presence of glucose. the physiological background of this signal and its connection with nh+4 ion uptake and/or metabolism is discussed. the response time of the sensor is about 5-10 s for nh+ ...19901367422
a 34- to 38-kilodalton cryptococcus neoformans glycoprotein produced as an exoantigen bearing a glycosylated species-specific epitope.three monoclonal antibodies (mabs), all of the immunoglobulin g1 subclass, were raised against cryptococcus neoformans by using the technique of cyclophosphamide ablation of b-cell responses against shared epitopes of the cross-reactive fungus trichosporon beigelii. mab 3c2 was reactive against the encapsulated and nonencapsulated isolates of c. neoformans var. neoformans by enzyme-linked immunosorbent assay (elisa) and western blot (immunoblot), and in addition to a 34- to 38-kda determinant, i ...19921370270
impact of the changing epidemiology of fungal infections in the 1990s.the increase in fungal infections over the past decade is striking. this is particularly true for hospitalized patients where the rate of candidal bloodstream infection has increased by as much as 487% over the decade of the 1980s. this increase in fungal infections is accompanied by a significant excess mortality and excess length of stay in hospital. the emergence of "new" fungal pathogens such as candida krusei, torulopsis glabrata, fusarium and trichosporon beigelii is now recognized as a si ...19921396747
evaluation of a new system for the rapid identification of clinically important yeasts.the rapid system developed by huppert et al. (1975) for the identification of yeasts based on assimilation and fermentation patterns and on germ tube and pseudohyphal production was evaluated in a comparative study with conventional procedures. the 95 test cultures were members of the genera candida, cryptococcus, rhodotorula, saccharomyces, torulopsis, and trichosporon. the study revealed that approximately 94% of the isolates were correctly identified by the rapid method in comparison with the ...1976965478
trichosporon terrestre sp. nov.a single strain representative of an undescribed trichosporon species, was recovered from soil. the cell wall of the strain corresponds in structure to cell walls of the ascomycetous yeasts. on the ground of x-ray inactivation data the strain is assumed to be diploid. a description of the new species is given.19751082301
yeast-like fungi recovered from normal human skin in nsukka (nigeria).the incidence of yeast-like fungi on normal skin was investigated in 52 healthy nsukka individuals comprising 21 adults, 24 children, and 7 infants. eighty-six isolates of yeasts and 2 of geotrichum candidum were recovered. the yeasts included candida tropicalis-36 isolates, c. guilliermondii-3, c. parapsilosis-2, candida spp. (unidentified)-16, cryptococcus albidus-6, trichosporon cutaneum-7, trichosporon spp.-8 and rhodotorula spp.-8 isolates. the isolates originated from various sites, predom ...19761085120
[clinical evaluation of flucytosine in patients with urinary fungal infections].the clinical effectiveness of flucytosine (5-fc) was evaluated in 52 patients with urinary fungal infections which were diagnosed because of the presence of both funguria (greater than or equal to 10(4) cfu/ml) and pyuria (greater than or equal to 5 wbc/hpf). the patients received oral daily doses of 5-fc ranging 20 to 150 mg/kg, with a mean treatment duration of 11 days. the 57 fungus strains isolated from urine specimens consisted of 51 candida spp. including 28 candida albicans, 10 candida gl ...19921433895
superficial mycoses in saudi arabia.between june 1988 and december 1990, 1018 cases of superficial mycoses were investigated. diagnosis was confirmed by microscopic examination in 503 cases and the causal agent was isolated in 490 cases. tinea capitis accounted for 47.7% (92.5% in children below 10 years of age). the frequency of other clinical types in descending order was pityriasis versicolor 25.8%, tinea corporis 9%, onychomycosis 5.8%, tinea pedis 4%, intertrigo 3.9% and tinea cruris 2.8%. erythrasma was encountered three tim ...19921445094
azole therapy for trichosporonosis: clinical evaluation of eight patients, experimental therapy for murine infection, and review.we studied the in vivo antifungal activity of azoles in humans and in a murine model of disseminated trichosporonosis. eight patients infected with trichosporon species were treated with fluconazole, sch 39304, or miconazole for 2-26 weeks. four patients had fungemia, two patients had disseminated trichosporonosis, and one patient each had soft-tissue infection and cystitis. response of trichosporonosis to azoles was seen in all eight patients, although one patient died with disseminated aspergi ...19921445976
cutaneous involvement of systemic fungal infections in neutropenic patients.skin nodules can be the first evidence of a disseminated fungal infection in febrile neutropenic patients. we present our experience in the diagnosis of this clinical problem in five patients treated for serious hematologic conditions in our service. there were two cases of candida sp., two of fusarium sp., and one of trichosporon sp.. the immediate assessment of any suspicious lesion, including a biopsy of the lesion for microbiological and histopathologic examinations, will usually lead to the ...19921289191
[clinical study of bronchial inhalation challenge in summer-type hypersensitivity pneumonitis induced by trichosporon cutaneum].to evaluate the methods and criteria of judgement for the bronchial antigen inhalation challenge test, the test was performed with culture filtrate antigen of serotype i and ii of trichosporon cutaneum in 18 patients with summer-type hypersensitivity pneumonitis from 15 families. the quantity of 15 mg of culture filtrate antigen was adequate, and had no side effects. in the tests, 17 of 18 patients showed a positive reaction to both or either, serotype of antigen. in 36 performances of inhalatio ...19921484431
localized pulmonary disease due to trichosporon beigelii.a case of pulmonary infection caused by trichosporon beigelii is reported. the infection occurred in a neutropenic patient with acute lymphoblastic leukemia. his chest radiograph showed a 6-cm pulmonary infiltrate in the right midzone and an apical infiltrate on the left. repeated cultures of bronchoalveolar lavage grew budding yeast that was identified as t beigelii on the basis of morphological, cultural, and biochemical characteristics. he responded to amphotericin-b therapy. systemic infecti ...19921495118
neotypification of the genus trichosporon.the currently accepted type species of the genus trichosporon behrend is t. beigelii. this species has formerly been regarded as identical to t. cutaneum. however, these fungi are now known to represent separate species with different ecology. the first species described in trichosporon was t. ovoides, an agent of human white piedra. a neotype strain is designated for this species, while a lectotype strain is indicated for t. cutaneum. the name t. beigelii is considered as doubtful and consequen ...19921497333
contributions to a revision of the genus trichosporon.the genus trichosporon was revised using characters of morphology, ultrastructure, physiology, ubiquinone systems, mol% g + c of dna, dna/dna reassociations and 26s ribosomal rna partial sequences. a total of 101 strains was used, including all available type and authentic cultures of previously described taxa. nineteen taxa could be distinguished, 15 of which having q-9 coenzyme systems and 4 having q-10. sixteen previously described names were reduced to synonymy. one new species was described ...19921497334
generation of genetic recombinants in trichosporon cutaneum by spontaneous segregation of protoplast fusants.auxotrophic mutants were isolated in two strains of trichosporon cutaneum. complementing auxotrophs were hybridized by protoplast fusion. some of the fusants were apparently transient diploids and segregated to give recombinant marker combinations.19921512572
catheter-associated septicaemia due to trichosporon capitatum. 19921362742
[the enzymatic hydrolysis of cell wall applied to yeasts classification (author's transl)].the rigid structure of yeast cell wall may be a taxonomic criterion. using the helix pomatia juice (with mercaptoethylamine hydrochloride) as a polyenzymatic system, we have always obtained protoplasts from ascomycetous yeasts and never from basidiomycetous yeasts tested. then, we have applied this enzymatic analysis to the fungi imperfecti yeasts and, according to this test, separated genus looking like basidiomycetous behaviour: trichosporon, pityrosporum, rhodotorula, cryptococcus and non fer ...19751190637
trichosporon beigelii: a potential cause of sepsis in premature infants.trichosporon beigelii is an emerging pathogen, often resistant to amphotericin b, that causes disseminated infection in immunocompromised patients. early identification of this organism and knowledge of sensitivity patterns to antifungal agents may decrease the high mortality rate for immunocompromised patients with disseminated trichosporosis. i have reported a case of septicemia associated with t beigelii in a premature twin infant who had been granulocytopenic since birth.19921470973
antifungal activities of salivary histidine-rich polypeptides against candida albicans and other oral yeast isolates.twenty-six oral yeast isolates from 26 donors were tested for their susceptibility to salivary histidine-rich polypeptide-4 (hrp-4) in blastospore viability assays. hrp-4 was observed to inhibit blastospore division in all of the yeast isolates, although inhibition was variable depending upon both species and strain tested. nine species of candida and 2 strains of trichosporon pullulans were included in the study. no significant differences in susceptibility to hrp-4 could be seen, irrespective ...19921528625
approaches to management of fungal infections in cancer patients.the patient most susceptible to invasive aspergillosis has had prolonged granulocytopenia resulting from intensive chemotherapy and/or radiation therapy, aplastic anemia, or acute leukemia. the sinuses and lungs are usually involved, but the infection may disseminate to the endocardium, skin, cns, and eye. efficacy of antifungal treatment with amphotericin b depends on early recognition and aggressive intervention. in severe or refractory cases, addition of flucytosine, rifampin, or fluconazole ...19921534671
cutaneous manifestations in systemic trichosporonosis.trichosporonosis due to trichosporon beigelii is increasingly recognized in neutropenic immunocompromised patients. we report the clinical and histological presentation of three cases, as well as a study of the prevalence of t. beigelii colonization of normal-looking skin in patients receiving intensive chemotherapy for cancer.19921516247
disseminated neonatal trichosporon beigelii. 19921549411
fungal diseases of the nasal cavity of the dog and cat.fungal infections of the nasal cavity are a common cause of nasal disease in the dog and cat. aspergillus fumigatus most commonly affects the dog; cryptococcus neoformans is the most common fungus isolated from the cat. rhinosporidium infection causes obstructive nasal polyps in the dog but has not been reported in the cat. several other miscellaneous fungi, including exophiala, alternaria, trichosporon, blastomyces, and histoplasma, and the alga prototheca occasionally cause nasal disease in do ...19921523784
[a comparative study of the effect of pyrazole on the activity of enzymes in the alcohol/polyol dehydrogenase family].a comparative study of the effect of pyrazol, an inhibitor of the coenzyme-binding site of alcohol dehydrogenases, on the activity of enzymes of the alcohol/polyol dehydrogenase group has been carried out. commercial preparations of alcohol dehydrogenases from the cytoplasm of horse liver cells and yeast cells, as well as the enzyme from the cytoplasm of trichosporon pullulans cells was completely inhibited by 1 mm pyrazol, while alcohol dehydrogenases from candida utilis and saccharomyces carls ...19921594544
endocarditis caused by blastoschizomyces capitatus and taxonomic review of the genus.blastoschizomyces capitatus salkin, gordon, samsonoff et rieder was found to be the etiologic agent of endocarditis in a patient with a prosthetic mitral valve. cultures inoculated with peripheral blood and portions of the valve yielded b. capitatus. examination of stained tissue sections revealed the presence of fungal filaments morphologically consistent with this organism. the salient characteristics of b. capitatus and the factors contributing to its recognition as a distinct taxon are descr ...19921400996
[analysis of 84 cases with fungemia].eighty-four patients with fungemia were analyzed. fungi had been isolated by culture of blood samples, including blood from the catheter for intravenous hyperalimentation, between 1986-1990. candida albicans (39.3%), candida parapsilosis (20.2%), candida tropicalis (11.9%), candida glabrata (10.7%), candida guilliermondii (4.8%) and trichosporon beigelii (4.8%) were the most frequently isolated fungal pathogens. four patients' blood yielded two different fungal species. fifty-nine cases were mal ...19921402094
[a case of trichosporon beigelii peritonitis in capd].continuous ambulatory peritoneal dialysis (capd) was introduced to japan ten years ago and was established as the treatment for end-stage renal disease along with hd. although the incidence of peritonitis in capd has decreased by educating the patients and parents and the improvement of various devises of capd, peritonitis is still one of the major complications of capd. fungus is a rare pathogen for peritonitis in capd, but it must be considered as a causative agent in cases of intractable peri ...19921402121
phenol hydroxylase from trichosporon cutaneum: gene cloning, sequence analysis, and functional expression in escherichia coli.a cdna clone encoding phenol hydroxylase from the soil yeast trichosporon cutaneum was isolated and characterized. the clone was identified by hybridization screening of a bacteriophage lambda zap-based cdna library with an oligonucleotide probe which corresponded to the n-terminal amino acid sequence of the purified enzyme. the cdna encodes a protein consisting of 664 amino acids. amino acid sequences of a number of peptides obtained by edman degradation of various cleavage products of the puri ...19921429434
in vitro activity of sertaconazole.the activity of 7-chloro-3-[1-(2,4-dichlorophenyl)-2-(1h-imidazol-1-yl) ethoxy-methyl]benzo[b]thiophene (sertaconazole, fi 7045, cas 99592-32-2), a new topical antifungal, was studied in vitro against several infecting organisms. the results obtained show that sertaconazole is a broad-spectrum antifungal against yeasts (c. albicans, c. tropicalis, c. pseudotropicalis, c. krusei, trichosporon and cryptococcus), dermatophytes (microsporum, trichophyton and epidermophyton), opportunistic filamentou ...19921627186
in vitro antifungal activity of sertaconazole.the antifungal activity of 7-chloro-3-[1-(2,4-dichlorophenyl)-2-(1h- imidazol-1-yl)ethoxy-methyl]benzo[b]thiophene (sertaconazole, fi-7045, cas 99592-32-2) versus miconazole has been studied in vitro against yeast-like fungi, dermatophytes and other filamentous fungi. candida albicans was very sensitive to sertaconazole both in serotype a and serotype b strains (mic = 0.21 micrograms/ml). sensitivity of candida non albicans species (mic = 0.17 microgram/ml), torulopsis (mic = 0.09 microgram/ml) ...19921627187
a novel murine model of disseminated trichosporonosis.serious infections caused by trichosporon beigelii have been noted with increasing frequency in immuno-compromised patients. progress in understanding the pathogenesis of this emerging infection has been limited by the lack of an animal model. we developed a cf1 mouse intravenous inoculation model of disseminated trichosporonosis to evaluate the pathogenicity of t. beigelii in transiently immunosuppressed mice. four inocula (1 x 10(6), 1 x 10(7), 2 x 10(7), and 4 x 10(7) cfu per animal) of one c ...19921639502
successful surgical management of septic arthritis due to trichosporon beigelii in a patient with acute myeloid leukaemia.a greek male with acute myeloid leukaemia (aml) developed a pyrexial illness while neutropenic and trichosporon beigelii was isolated from his skin, blood and urine. this infection appeared to resolve with a rising neutrophil count, but recurred in the next episode of neutropenia. t. beigelii was isolated from an aspirate from an inflamed knee. despite a rising neutrophil count resolution only occurred after surgical drainage and local irrigation with miconazole.19921641603
[in vitro antifungal activity of itraconazole, a new triazole antifungal agent, against clinical isolates from patients with systemic mycoses].the in vitro antifungal activity of itraconazole (itz), a new oral triazole antifungal agent, against clinical isolates from patients with systemic mycoses were compared with those of existing systemic antifungals, viz. ketoconazole (kcz), miconazole or amphotericin b. the studies were performed with 65 isolates of pathogenic yeasts and 13 isolates of aspergillus spp. using the agar dilution method on casitone agar. itz showed the most potent antifungal activities against isolates of pathogenic ...19911652654
evaluation of the baxter-microscan 4-hour enzyme-based yeast identification system.a new 4-h yeast identification panel (yip; baxter-microscan, w. sacramento, calif.) was compared with the api 20c yeast identification system (analytab products, inc., plainview, n.y.) in the identification of recent clinical yeast isolates. the yip had a 94% correlation (288 of 306) in identifying 22 species within the genera candida, hansenula, pichia, rhodotorula, saccharomyces, and torulopsis. correlation dropped to 65% for those species within the genera of slower growing yeasts, i.e., blas ...19911653786
lowered responsiveness of bronchoalveolar lavage t lymphocytes in hypersensitivity pneumonitis.we previously reported that trichosporon cutaneum was the major causative antigen of summer-type hypersensitivity pneumonitis (hp) in japan. in summer-type hp patients, we noticed that the proliferative responses of bronchoalveolar lavage (bal) lymphocytes to phytohemagglutinin (pha) and concanavalin a were significantly lower than those of the peripheral blood lymphocytes of the same patients. it was shown in this study that the low response of bal lymphocytes was due to an intrinsic lowering o ...19911673617
distinction of deep versus superficial clinical and nonclinical isolates of trichosporon beigelii by isoenzymes and restriction fragment length polymorphisms of rdna generated by polymerase chain reaction.fifteen clinical and environmental strains of trichosporon beigelii were analyzed for similarities by using morphological features, biochemical profiles based on carbon compound assimilation and uric acid utilization, isoenzyme electrophoresis, and restriction fragment length polymorphisms of a segment of genes coding for rrna expanded with the polymerase chain reaction. the findings suggest that strains that cause invasive disease are distinct from the superficial and the nonclinical isolates a ...19911684798
importance of serotype-related antigen in the induction of experimental hypersensitivity pneumonitis by trichosporon cutaneum in rabbits. correlation between granulomatous alveolitis and cellular and humoral immune responses to polysaccharide-rich antigen.we evaluated the immunopathogenic properties of trichosporon cutaneum, a major etiologic agent of japanese summer-type hypersensitivity pneumonitis (hp). when the culture filtrate antigen of t. cutaneum was chromatographed on deae-cellulose, two peaks of polysaccharide, fractions a and b, were obtained. fraction b was highly reactive to the specific igg and iga antibodies in the serum and bronchoalveolar lavage fluid samples obtained from sensitized rabbits, whereas fraction a was mainly reactiv ...19901689976
cysto-peritoneal shunt infection with trichosporon beigelii.infection is a frequent problem affecting cysto-peritoneal shunts, the usual causative organisms being staphylococcus epidermidis and staphylococcus aureus. fungi are rarely isolated from such infections. we present the first report, as far as the authors are aware, of a case of trichosporon beigelii shunt infection that responded to shunt removal and antifungal therapy.19911764234
fungal infections in cancer patients: an escalating problem.major advances in anticancer treatment have contributed to an increased frequency of severe fungal infections in patients with neoplastic diseases. neutropenia remains the most important among the predisposing factors related to the malignancy or its treatment. most fungal infections are caused by the commonly recognized opportunistic fungi candida spp and aspergillus spp, and the pathogenic fungi cryptococcus neoformans, histoplasma capsulatum, coccidiodes immitis, and less often by blastomyces ...19921525339
orofacial fungal infections. nine pathogens that may invade during chemotherapy.immunosuppression due to antineoplastic drugs or malignant tumor leaves patients extremely vulnerable to infection. opportunistic fungi that rarely infect healthy persons can have very severe consequences in these patients. candida albicans is the pathogen found most often, but several other candida species may cause infection as well. aspergillosis is the second most frequently seen fungal infection of the face and mouth in patients receiving chemotherapy. less commonly seen but equally dangero ...19921561171
fungal infection in neonates. 19911778847
white piedra.a 39-year-old thai man had eczema on the left groin accompanied by asymptomatic white nodules on the public hair for two weeks. examination with the wood's lamp, microscopic examination, culture and biochemical testing showed organisms compatible with trichosporon beigelii. the diagnosis of "white piedra" was made, and this is the first case of white piedra to be reported in thailand.19911781759
experimental trichosporon infection in persistently granulocytopenic rabbits: implications for pathogenesis, diagnosis, and treatment of an emerging opportunistic mycosis.disseminated trichosporon infection, an uncommon but emerging opportunistic mycosis due to trichosporon beigelii, is frequently difficult to diagnose, refractory to treatment, and associated with a high attributable mortality. models of disseminated and gastrointestinal trichosporon infection were developed in persistently granulocytopenic rabbits. the patterns of infection resembled those of clinical disease, including cutaneous lesions, chorioretinitis, renal infection, pulmonary infection, an ...19921535092
[a case of severe summer-type hypersensitivity pneumonitis treated with high-dose administration of steroid].a 40-year-old man who lived in a wooden house built 30 years ago presented with complaints of fever, dry cough and dyspnea. chest x-ray findings showed interstitial shadows throughout bilateral lung fields. after admission, high-dose administration of 3000 mg of methylprednisolone was performed because of deterioration of chest x-ray shadows and symptoms. in a week, clinical data and symptoms improved. findings of bal fluid on admission revealed a relative increase of lymphocytes, neutrophils an ...19911770686
fatal trichosporonosis is not related to tolerance to amphotericin b.a case of disseminated trichosporonosis in a 45-year-old female suffering from acute lymphocytic leukaemia is reported. the patient died of that mycosis despite of therapy with amphotericin b for which the pathogen had been proven susceptible in vitro.19911803234
effect of culture media on in vitro susceptibility testing of fluconazole against some yeasts.thirty clinical isolates, comprising six strains of candida albicans, and four strains each of c. lusitaniae, c. parapsilosis, c. tropicalis, cryptococcus neoformans, torulopsis glabrata and trichosporon beigelii were tested against fluconazole, using sabouraud's dextrose (sd) broth and a high resolution (hr) medium (pfizer central research, inc.). the procedure was a standard tube (1 ml/tube) dilution, and c. albicans y01 09 was included as a reference strain to monitor quality and reproducibil ...19911803235
[focal hepato-splenic mycosis caused by trichosporon beigelii in a patient with acute leukemia].we report a case of infection produced by trichosporon beigelii in a patient with acute leukaemia. in spite of treatment with amphotericin b the patient died and the necropsy studies showed only involvement of liver and spleen without disseminated infection. focal hepatosplenic fungal infection has been recognized with increasing frequency in recent years as a serious complication in immunosuppressed patients. usually it is produced by candida spp and this is the first case described in the lite ...19911776110
analysis of cases of central nervous system fungal infections reported in japan between january 1979 and june 1989.data from 129 cases of central nervous systemic fungal infections reported in japan between january 1979 and june 1989 were analyzed. of 129 cases, 116 were cryptococcal meningitis, 6 candidal meningitis (including meningitis due to trichosporon cutaneum) and 7 aspergillus meningoencephalitis. fifty-six of the patients with cryptococcal meningitis had an underlying systemic disease or condition. the overall survival rate was 72.4%, which was a markedly improved rate compared to earlier reports. ...19921600262
antifungal prophylaxis during neutropenia or allogeneic bone marrow transplantation: what is the state of the art? ad hoc working group.neutropenia induced by intensive chemotherapy and allogeneic bone marrow transplantation are increasingly commonly complicated by fungal infections; thus prophylaxis may be justified. the authors surveyed the literature and culled their experience - few randomized trials have been done and definitions have often been poor. in prophylaxis of mucosal candidosis, miconazole and clotrimazole may both be more effective than placebo. nystatin is ineffective and ketoconazole of medicine efficacy. fluco ...19921611930
trichosporon beigelii pneumonitis following busulphan-induced leucopenia.we present a 41 yr old male, who died of respiratory failure due to infiltration of trichosporon beigelii (cutaneum) into the pulmonary interstitial spaces with systemic dissemination. busulphan-induced leucopenia in the chronic phase of chronic myelogenous leukaemia had progressed before this infection developed. in leukaemic patients with profound leucopenia, interstitial pneumonitis due to t. beigelii should be considered as a possible cause of otherwise unexplained hypoxaemia.19921612161
arxula adeninivorans, a yeast assimilating many nitrogenous and aromatic compounds.a detailed description of the yeast species arxula adeninivorans (syn. trichosporon adeninovorans) was given. the yeast assimilated all the sugars, polyalcohols and organic acids used in the conventional carbon compound assimilation test rapidly, except for l-rhamnose, inulin, lactose, lactate and methanol. as nitrogen sources served all conventionally used compounds except creatine and creatinine. several nitrogenous compounds, e.g. amino acids, purine derivatives, served as sole source of carb ...19911854187
a case of trichosporon pullulans infection of the lung with adult t-cell leukemia.fungal infections are often reported, but trichosporon infection is very rare. a 78-year-old man with adult t-cell leukemia complicated with pulmonary infections is presented. bronchial exudate culture revealed many yeast-like colonies, which were morphologically and biochemically identified as trichosporon pullulans.19911865584
[clinical features of 32 cases of fungal pneumonia].a total of 32 patients with mycoses other than cavity-formed aspergilloma were reviewed. the main pathogenic fungi were aspergillus in 14, candida in 8, cryptococcus in 4, trichosporon in 4 and mucor in 2. coinfection by two species was detected in 3 cases: trichosporon and aspergillus in 2 and aspergillus and candida in 1. the underlying diseases were hematologic malignancies in all cases except 1 case of lung cancer. the hematologic malignancies were mostly leukemias of various types. cryptoco ...19911865594
endocarditis due to trichosporon beigelii: in vitro susceptibility of isolates and review.infection with trichosporon beigelii is an uncommon cause of endocarditis. of the eight cases of t. beigelii endocarditis that have been reported (one herein and seven previously), six involved prosthetic heart valves and two involved native heart valves. the clinical manifestations of this infection included embolization of the superficial femoral artery or of the bifurcation of the posterior tibial and peroneal arteries in three of these patients (two with prosthetic valve and one with native ...19911866540
Displaying items 1 - 100 of 1387