| the effect of microbial mycolytic agents on trichophyton rubrum. | chitinolytic microorganisms isolated from forest soil and from healthy gypsy moth larvae (porthetria dispar (l.) were screened for their ability to lyse trichophyton rubrum mycelia. a few of these isolates were mycolytic on both autoclaved and on actively growing, intact, t. rubrum mycelia. supernatants from these isolates, utilizing live t. rubrum as the sole carbon source, showed the same mycolytic ability. assays of the supernatants for enzymatic activity revealed exocellular, stable enzymes ... | 1975 | 1677 |
| pigment formation by trichophyton rubrum: differentiation between t. rubrum and t. mentagrophytes on serum albumin agar (author's transl). | on serum albumin agar (bovine albumin) with initial ph-values of 5.0-6.0, trichophyton rubrum showed a yellow pigmentation, and on the same medium with an initial ph-value of 7.0, a red pigmentation. strains of trichophyton mentagrophytes have never shown pigmentation until now, the scarce growth (submerged) of t. rubrum on serum albumin agar is associated with a pigment formation that may be used for diagnostic purposes. it could be read within 3-7 days. serum albumin agar with the initial ph-v ... | 1977 | 15390 |
| lipolytic enzymes of trichophyton rubrum. | trichophyton rubrum cells contain lipase, phospholipases a and b and acyl coa lysolecithin acyl transferase activities. this dermatophyte excretes lipase and phospholipase a into the growth medium when cultivated in sabouraud's broth. extracellular lipase has optimum activity at ph 8.0 whereas the intracellular lipase is maximally active at ph 8.0 whereas the intracellular lipase is maximally active at ph 7.0. the optimum ph of phospholipase a and b activities which are localized in 15000 g sedi ... | 1977 | 23589 |
| serum-albumin agar used as slant for the differentiation between trichophyton rubrum and trichophyton mentagrophytes: specific reg pigmentation of t. rubrum. | trichophyton rubrum strains freshly isolated from clinical material exhibited red pigment formation within 7 days at 26 degrees c on slant serum-albumin agar, initial ph 7.0. in trichophyton mentagrophytes strains this phenomenon could not be observed. since in the case of t. rubrum, yellow pigmentation will appear at an initial ph of 5.0, the use of initial ph values of 7.0 and 5.0 is recommended for diagnostic application of slant serum-albumin agar. | 1978 | 29418 |
| [age-related changes in the ultrastructure of trichophyton rubrum]. | | 1975 | 50677 |
| studies of the antigenic structure of trichophyton rubrum, trichophyton mentagrophytes, microsporon canis, and epidermophyton floccosum by crossed immuno-electrophoresis. | by means of crossed immuno-electrophoresis, 35 antigens of t. rubrum, 26 of t. mentagrophytes, 35 of m. canis, and 25 of e. floccosum have been demonstrated. tandem crossed immuno-electrophoresis has revealed two antigens common to t. rubrum and the other species, which, however, differ within the species. no common antigens have been demonstrated between t. mentagrophytes, m. canis, and e. floccosum. the technique for preparation of extracts and production of immune serum is described, and the ... | 1976 | 60875 |
| toxic fatty acid resistant mutant of trichophyton rubrum. | a mutant of trichophyton rubrum which could tolerate high concentration (110 microgram/ml) of undecanoic acid was isolated from undecanoic (27.5 microgram/ml) sensitive parent. the mutant showed cross resistance towards other fatty acids like propionic acid, caprylic acid and undecenoic acid which were toxic for the parent strain. development of fatty acid resistance in the mutant strain was associated with increased pigment production. there was no difference in colony or cell morphology betwee ... | 1977 | 75669 |
| control of exocellular proteases in dermatophytes and especially trichophyton rubrum. | the production of proteases was investigated during growth of dermatophytic fungi with special emphasis on trichophyton rubrum. exogenous glucose suppressed elastase production in all dermatophytes examined. the production of protease active guinea pig hair in keratin-salts broth by microsporum gypseum. trichophyton mentagrophytes and t. rubrum was also suppressed by glucose. various carbohydrates added to keratin-salts broth curtailed protease production by t. rubrum as did individual amino aci ... | 1979 | 94467 |
| chronic trichophyton rubrum infection and bloodgroups. | | 1979 | 115928 |
| trichophyton rubrum infections according to age, anatomical distribution and sex. | trichophyton rubrum caused 72.9% of the cases of dermatophytosis observed in a sample of caucasoids from philadelphia. tinea pedis was found in 84% of the female and male patients with dermatophytosis. tinea manuum occurred with equal frequency in both sexes whereas tinea unguium was more prevalent in females. tinea cruris occurred almost exclusively in males. infections of two or more anatomical sites were observed more frequently in males. the data are compared with those reported by rosman (1 ... | 1975 | 125094 |
| fungal diseases in shiraz. | in 122 patients with fungal diseases studied over a six month period, sixty were seen with dermatophyte infections. tinea pedis, cruris and ungruium occurred mainly in adult males attending the private hospital and tinea corporis and capitis children attending the university hospital. the organisms found were trichophyton rubrum, t. mentagrophytes, t. schonleinii, t. tonsurans, epidermophyton floccosum and microsporum canis. infections with candida albicans occurred both in the urban and rural p ... | 1978 | 148630 |
| [energy metabolism of the skin in dermatomycoses caused by trichophyton rubrum]. | | 1978 | 207041 |
| skin infections in kaimai rail tunnel construction workers. | skin lesions in kaimai rail tunnel workers were noted to respond poorly to treatment and investigations revealed that this was because the lesions were either gram-negative infections or trichophyton rubrum infections. | 1977 | 272510 |
| [on the ultrastructural observation of fungal elements in trichophyton rubrum granuloma (author's transl)]. | | 1979 | 314538 |
| experimental inoculation with trichophyton rubrum (castellani) sabouraud in patients with pemphigus and related dermatoses. | | 1977 | 321955 |
| determination of biogenous amines in fungus-cultures (candida albicans, trichophyton mentagrophytes, trichophyton rubrum and microsporum canis) by thin-layer chromatography and mass-spectrometry. | | 1978 | 366401 |
| [in vitro effectiveness of salicylic, benzoic and boric acid and diiodine thymol solutions on various strains of dermatophytes]. | in order to study the in vitro behavior of the drug used according to our formula cultures of trichophyton mentagrophytes. trichophyton rubrum, trichophyton verrucosum, trichophyton tonsurans, microsporum canis, microsporum gallinae, microsporum audouinii, microsporum gypseum and epidermophyton floccosum were prepared in order to prove its efficacy. it was found no growth in cultures to which the drug was added in different concentrations thus proving its efficacy as a fungistatic element. the i ... | 1979 | 395583 |
| econazole effects on trichophyton rubrum and candida albicans--electron microscopic and cytochemical studies. | | 1978 | 400880 |
| [skin ultrastructure in rabbits with experimental mycosis caused by trichophyton rubrum]. | | 1979 | 419871 |
| comparison of in vitro activity of undecylenic acid and tolnaftate against athlete's foot fungi. | undecylenic acid and tolnaftate were tested in an in vitro test system to evaluate their relative "killing time" efficacy against trichophyton mentagrophytes, trichophyton rubrum, and epidermophyton floccosum. commercial products containing these active agents were tested similarly. the pure active agents were equivalent in activity. the commercial product containing undecylenic acid appeared to be more effective against the test organisms than did the product containing tolnaftate. | 1979 | 423138 |
| [trichophyton rubrum infection simulating duhring's disease in chronic schizophrenia]. | | 1979 | 424620 |
| [electron microscopic study of the ultrastructure of trichophyton rubrum in culture]. | | 1979 | 425698 |
| concomitant erythrasma and dermatophytosis of the groin. | four patients are reported with concomitant erythrasma and trichophyton rubrum dermatophytosis of the groin. the recognition and diagnosis of these associated infections is emphasized. | 1979 | 427017 |
| an additional case of canine dermatophytosis caused by trichophyton rubrum. | | 1979 | 430934 |
| comparative study of the growth inhibition of vegetative hyphae of some dermatophytes and keratinophilic fungi on glucose-peptone-agar with griseofulvin. | by the method of jesenská and danilla [29] the growth inhibition of vegetative hyphae of colonies of 12 species of dermatophytes and keratinophilic fungi on the surface of glucose-peptone-agar with incorporated griseofulvin has been established. it could be concluded that the sensitivity of hyphae to griseofulvin is neither connected with the taxonomic position and ecological classification of these microscopic fungi, nor with their ability to survive in the soil, or with their pathogenity etc. ... | 1979 | 456713 |
| an unusual lipid in the human pathogenic fungus epidermophyton floccosum. | the dermatophyte epidermophyton floccosum contains an unusual lipid characterized as 1(3),2-diacylglyceryl-3(1)-o-4'-(n,n,n-trimethyl)homoserine. its concentration in e. floccosum is approx. 15% of the polar lipids. the role of this lipid in the biosynthesis of polar lipids and fatty acids is not yet known. however, it is interesting from a chemotaxonomic viewpoint that the lipids from two other genera of dermatophyte, microsporum cookei and trichophyton rubrum do not contain this novel lipid. | 1979 | 486519 |
| [relationship between the clinical characteristics and types of specific humoral immunologic reactions in mycosis caused by trichophyton rubrum]. | | 1979 | 506453 |
| imported fungal infections. | data on mycoses known to be imported into the united kingdom are sparse. estimates on the prevalence of fungal infections have to be based on indirect and incomplete figures, obtained from isolation figures and reports of individual cases to co-ordinating centres such as the mycological reference laboratory and the communicable disease surveillance centre of the public health laboratory service. imported species of dermatophytes account for less than 1% of the total number of isolations made ann ... | 1979 | 523346 |
| failure of treatment in chronic dermatophyte infections. | a proportion of dermatophyte infections fail to respond to normally adequate courses of griseofulvin and topical antifungal therapy. the organism trichophyton rubrum was isolated from 96% of 50 patients studied, but no instances of in vitro resistance were seen. of these patients, 57% had an underlying condition, commonly hay fever/asthma, atopic eczema, collagen disease or ichthyosis. defective delayed type hypersensitivity responses and leucocyte migration inhibition to the specific antigen, t ... | 1979 | 523349 |
| [the afro-asian variety of trichophyton rubrum in czechoslovakia (author's transl)]. | | 1979 | 527061 |
| [ontogenic changes in the ultrastructure of trichophyton rubrum based on scanning electron microscopy]. | | 1977 | 595832 |
| trichophyton fischeri sp. nov.: a saprophyte resembling trichophyton rubrum. | a new species trichophyton fischeri was isolated as a contaminant on blood agar plates. this fungus is believed to be a saprophyte. it may be confused with t. rubrum. on peptone dextrose agar plate, the growth is white and velvety to cottony. it occasionally forms furrows. the underside of the mature colony is brownish red. clavate microaleuriospores are common. trichophyton-type macroaleuriospores are produced occasionally on blood agar and potato dextrose agar. erythritol does not stimulate t. ... | 1977 | 601659 |
| immune responses in patients with chronic trichophyton rubrum infections. | | 1977 | 603976 |
| tinea faciei. | a 62-year-old man had a long-standing fungal infection of the face. the eruption had been treated as a photosensitivity disorder for 22 years. a literature review revealed only 35 reported cases classified as tinea faciei, most of which also were misdiagnosed originally. pertinent clinical findings include facila erythema, pruritus, and scaling patches with arcuate or annular borders. the most common organisms isolated with trichophyton rubrum or t mentagrophytes. to our knowledge, this unique c ... | 1978 | 629551 |
| [value and method of the urease test in the differentiation of trichophyton rubrum and trichophyton mentagrophytes]. | | 1978 | 680296 |
| variation in trichophyton rubrum. | | 1978 | 723914 |
| [effect of griseofulvin/on the riboflavin and nicotinic acid content in patients with tinea pedis caused by trichophyton rubrum]. | | 1978 | 735339 |
| [specific immune reactions of blood cells in patients with trichophyton rubrum infection]. | | 1978 | 740017 |
| hereditary c2 deficiency associated with cutaneous lupus erythematosus: clinical, laboratory, and genetic studies. | selective congenital deficiency in the second component of complement has been described in association with lupus erythematosus (le) and other connective tissue disorders. we identified a 59-year-old woman with a 13-year history of cutaneous le and no detectable serum c2. the patient's photosensitivity, large polycyclic erosive cutaneous lesions, lack of renal disease, paucity of serological findings, and high incidence of bacterial infection is consistent with previously described patients wit ... | 1979 | 760659 |
| experimental inoculation of dermatophytes on psoriatic skin. | two dermatophytic agents, trichophyton rubrum and trichophyton mentagrophytes were used in the experimental inoculation of psoriatic lesions in 27 volunteer patients (13 males and 14 females with an age range from 17 to 72 yr). t. rubrum was inoculated in 14 patients and t. mentagrophytes (varietas granulare) in 13. for purposes of control in each patient the same agent was also inoculated on healthy skin. results were noted once a week for a period of 1 mo. a positive response was found in 12 o ... | 1979 | 762446 |
| clinical evaluation of clotrimazole. a broad-spectrum antifungal agent. | the efficacy and safety of the broad-spectrum, topically applied antifungal agent clotrimazole were evaluated in two double-blind, multicentric trials. ten investigators reported on a total of 1,361 cases in which a 1% solution or a 1% cream formulation was compared with its respective vehicle. clotrimazole was therapeutically effective, as confirmed by mycological cure (negative microscopy and culture) and clinical improvement, in tinea pedis, tinea cruris, tinea corporis, pityriasis versicolor ... | 1976 | 769697 |
| tinea cruris: diagnostic confusion due to isolation of candida albicans alone. | the diagnostic importance of the isolation of candida albicans from a skin lesion is often uncertain. in a 68-year-old man from whose lesions only c. albicans was originally isolated trichophyton rubrum and epidermophyton floccosum were also isolated when the growth of the yeast was inhibited in a selective medium. the use of this selective medium, casamino acids erythritol albumin agar, ensures the proper interpretation of the significance of the presence of c. albicans in skin lesions. | 1976 | 773524 |
| ciclopirox: a new topical pyrodonium antimycotic agent. a double-blind study in superficial dermatomycoses. | one percent ciclopirox solution, a new topical antimycotic agent, was used in a double-blind controlled trial in 105 dermatomycosis patients. twelve of the patients were lost to follow-up. of the remaining ninety-three patients, forty-four were treated with the active drug, forty-nine with a placebo. the cure rate amongst those using ciclopirox was significantly superior to that of the placebo. the drug was effective against trichophyton rubrum, t. violaceum, t. mentagrophytes and malassezia fur ... | 1976 | 782504 |
| isolation of ethyl p-methoxycinnamate, the major antifungal principle of curcumba zedoaria. | an antifungal principle of the dried rhizomes of curcuma zedoaria was extracted with hot ethanol. by successive chromatography on neutral alumina and silica gel, three antibiotic compounds a, b, and c, all active against trichophyton rubrum, aspergillus niger and saccharomyces cerevisiae, were obtained in chemically pure form. by uv, ir, pmr and ms analysis, the structure of the most abundant one of these compounds (c, 69.8%; h, 6,8%; and 0.23.4%) was assigned as ethyl p-methoxycinnamate (epmc). ... | 1976 | 785141 |
| lymphocyte transformation in vitro in dermatophytosis. | peripheral blood lymphocytes from 59 patients with dermatophytosis and from nine young healthy women were studied by the lymphocyte transformation test (lt) using mitogens and bacterial as well as fungal antigens. the latter included candida albicans (ca) and four dermatophyte species, viz. trichophyton rubrum (tr), trichophyton mentagrophytes (tm), epidermophyton floccosum (ef) and microsporum canis (mf). most of the patients showed normal transformation in response to mitogens and non-dermatop ... | 1976 | 793301 |
| [ultrastructural cytopathology of the mycotic process caused by trichophyton rubrum in the dynamics]. | | 1975 | 808918 |
| dermatophyte isolation media: quantitative appraisal using skin scales infected with trichophyton mentagrophytes and trichophyton rubrum. | various dermatophyte isolation media were quantitatively appraised by colony counts for their ability to support growth when suspensions of trypsin-treated infected-skin scales were used as inocula. evaluation included guinea pig skin scales infected with a granular trichophyton mentagrophyton mentagrophytes, and one trial was conducted using human skin scales infected with trichophyton rubrum. no differences in the ability to support growth were observed among taplin dermatophyte test medium, d ... | 1977 | 833268 |
| sterols and sterol esters of trichophyton rubrum. | | 1977 | 863487 |
| [deep forms of mycosis caused by trichophyton rubrum]. | | 1977 | 878583 |
| tinea inguinalis treated with miconazole cream: a double-blind study. | a double-blind study on the effect of 2% miconazole cream and its vehicle was conducted on 84 men with tinea inguinalis. relief of itching and improved clinical and mycological cure rates were noted after 14 and 28 days of treatment with miconazole in patients in whom the causal agent was trichophyton rubrum. no conclusion about the efficacy of the active substance could be drawn in patients in whom the causal agent was some other dermatophyte or candida. | 1977 | 885711 |
| leukonychia trichophytica caused by trichophyton rubrum. | a case of leukonychia is reported, in which trichophyton rubrum was isolated from the nail plates and interdigital spaces of the toes. treatment consisted of oral griseofulvin, which produced appreciable improvement after ten months' therapy. | 1977 | 891245 |
| phospholipid turnover in trichophyton rubrum. | phospholipid synthesis, interconversion and breakdown in t. rubrum were followed by radioactive tracer. synthesis and catabolism of phosphatidyl ethanolamine and phosphatidyl serine are most rapid; phosphatidyl choline and phosphatidyl inositol are metabolised rather slowly. catabolism of phosphatidyl ethanolamine and phosphatidyl serine are uniform and their conversions to phosphatidyl choline and phosphatidyl inositol are suspected. | 1977 | 905923 |
| effect of undecanoic acid on germination of microconidia of wild and undecanoic acid resistance mutant of trichophyton rubrum. | effects of undecanoic acid (uda) on germination of microconidia and elongation of germ tubes in uda sensitive (udas) wild type trichophyton rubrum and uda resistant (udar) mutant derived from it, were studied. uda inhibited conidial germination of udas and udar strains at 30 microgram/ml and 120 microgram/ml respectively which were minimum inhibitory concentrations of uda for these two strains. when spores from both udas and udar were germinated in presence of subinhibitory concentration of uda, ... | 1977 | 917103 |
| [cellular and humoral immune reactions in fungus allergy]. | cellular and humoral immune reactions upon the polysaccharide preparations of trichophyton-rubrum-cultures have been proved in the most of 185 examined patients. quantitative and qualitative specific changes of the cells connected with their sensibilization, could be observed in the early period of trichophyton-rubrum-mycosis, in the course of the further development of the disease we also saw an accumulation of circulatory antibodies. humoral reactions have become predominant. the peculiarity o ... | 1977 | 923879 |
| in vitro and in vivo evaluation of versicolin, an antifungal antibiotic. | versicolin is mainly active against trichophyton rubrum. it is inactivated by serum. however, attainable blood level can be fifteen to twenty times higher than the fungicidal concentration for as long as 4 hours after a single intravenous administration of the maximum tolerable dose of 25 mg/kg body weight of mouse. it has no haemolytic activity like other polypeptide antibiotics. skin does not show the presence of any measurable amount of the antibiotic. it is excreted through urine to the exte ... | 1976 | 931794 |
| [a macroconidia-rich variant of trichophyton rubrum]. | | 1976 | 955202 |
| [multiple subcutaneous trichophyton rubrum abscesses. pathomorphosis of a generalized superficial tinea due to impaired immunological resistance]. | a patient with chronic polyarthritis is reported who was treated with corticosteroids over several years and also received azathioprine. the patient developed extensive tinea pedum and corporis which was suddenly complicated by multiple subcutaneous abscesses caused by the same organism, trichophyton rubrum. this type of dermatophytosis has only rarely been described. it shares some characteristics with the maladie dermatophytique of hadida and schousboe. chronic granulomatous dermatophytoses su ... | 1976 | 955893 |
| [miconazole per os in tinea and deep mycosis]. | for the last 6 years we have been using miconazole cream in the treatment of tinea and vaginal candidiasis. we think that it is at least as good as the best drugs for this purpose, but consider it difficult to decide about its superiority. therefore we refrain from describing this part of our experience in detail. we have employed miconazole "per os" at the daily doses of 24-28 mg./kg. in treating 3 cases of tinea corporis or cruris by "trichophyton rubrum". symptoms ceased in 3 days; mycologic ... | 1976 | 988459 |
| experimental dermatophytosis in guineapigs with trichophyton rubrum. | | 1976 | 992783 |
| [atypical forms of mycosis caused by trichophyton rubrum]. | | 1976 | 997888 |
| [role of the blood cells in specific allergic reactions in trichophyton rubrum infection]. | | 1976 | 1022111 |
| [cellular and humoral immunity response in patients with mycosis of the feet due to trichophyton rubrum]. | | 1976 | 1023632 |
| isolation of dermatophytes, candida species and systemic fungi from dermatologic specimens in montréal, 1963 to 1973. | of 10 057 specimens of scrapings from skin, nails and scalp examined for dermatophytes, yeasts, pityriasis versicolor and systemic mycoses between 1963 and 1973, 30.4 percent were positive for fungi. skin produced the highest proportion (68.6 percent) of positive scrapings, scalp the lowest (4.2 percent). trichophyton rubrum was the predominant species (23.6 percent); of lesser prevalence were microsporum canis (9.3 percent), t. mentagrophytes (8.4 percent) and epidermophyton floccosum (4.8 perc ... | 1975 | 1091342 |
| miconazole therapy for endemic fungal disease. | miconazole nitrate (2.0%) cream was evaluated in the treatment of endemic dermatophytosis in an overcrowded prison. the active drug was compared in a random double-blind study with its control vehicle in the treatment of 99 inmates who had moderate to severe symptomatic disease. tinea cruris and tinea pedis caused by trichophyton rubrum predominated, although trichophyton mentagrophytes and candida albicans were also isolated and identified. prompt clinical clearing occurred in 75.5% of those tr ... | 1975 | 1093481 |
| [study of the specific reactivity of the body in mycosis caused by trichophyton rubrum]. | | 1975 | 1098308 |
| canine ringworm caused by trichophyton rubrum; probable transmission from man to animal. | a case of ringworm in a 2-year-old male dachshund caused by trichophyton rubrum is described. the owner of this dog had tinea pedis probably caused by the same fungus. the authors believe that this is the first authenticated case of t. rubrum infection in a dog recorded in japan, the infection probably having been acquired from man. | 1975 | 1124460 |
| classification of some gymnoascaceae by pyrolysis-gas-liquid chromatography using added marker compounds. | methyl esters of fatty acids were added to samples before pyrolysis to superimpose peaks of known retention time on the pyrochromatograms. these peaks were useful in calibrating the retention time scales so that peaks on different chromatograms could be appropriately homologized. the study included 3 species of nannizzia, 3 strains of trichophyton rubrum and 1 strain each of gymnoascus uncinatus, g. reesii, arachniotus hyalinosporus, chrysosporium pannorum and gliocladium viride. pyrograms of th ... | 1975 | 1124463 |
| minor epidemic of trichophyton rubrum. | | 1975 | 1131629 |
| [comparative epidemiology of mycoses caused by zoophilic dermatophytes and an antropophilic species of trichophyton rubrum]. | | 1975 | 1139659 |
| isolation of chrysophanic acid-9-anthrone, the major antifungal principle of cassia tora. | an antifungal principle of defatted seed power of cassia tora linn. was isolated by extraction of an aqueous paste of the powder with benzene, followed by column chromatography over activated silica gel c using chloroform as the developing solvent. besides chrysophanic acid and other hydroxyanthraquinone derivatives, the major antifungal compound was identified as chrysophanic acid-9-anthrone, the structure of which was assigned on the basis of its chemical properties and uv, ir, nmr and mass sp ... | 1975 | 1143018 |
| letter: mycetoma and trichophyton rubrum. | | 1975 | 1148119 |
| [the effect of econazole on the fine structure of trichophyton rubrum cells]. | | 1975 | 1196335 |
| [exudative manifestation of mycosis caused by trichophyton rubrum]. | | 1975 | 1214465 |
| [possibilities in the serological differentiation of trichophyton rubrum species]. | | 1975 | 1222816 |
| trichophyton rubrum and t. mentagrophytes studied by freeze-etching. | | 1975 | 1224280 |
| antibodies with affinity for epithelial tissue in chronic dermatophytosis. | antibodies to dermatophytes which also had affinity for intercellular material of epithelial tissue, were detected in sera from 80% of patients with chronic dermatophytosis using an indirect fluorescent antibody test. the class of immunoglobulins reactive with both the dermatophyte and the epithelial tissue was identified as igm. igm antibodies with affinity for arthrospores of trichophyton mentagrophytes and intercellular substance of epithelial tissue could be removed from sera with mycelium o ... | 1975 | 1225650 |
| a study of the immunological status of patients with dermatophytoses. | 22 patients with trichophyton rubrum infection were studied for some of their immunological parameters. the trichophytin skin test performed with commercially available dermatophytin (hollister-stier) gave immediate positive reaction in 3 patients. all the other patients gave negative delayed and retarded reactions. in vitro response to pha of the peripheral lymphocytes was significantly depressed in patients compared to the controls. no relationship could, however, be established between the se ... | 1975 | 1225666 |
| a case of kerion with trichophyton rubrum. | | 1975 | 1234871 |
| dermatophyte infection in ichthyosis vulgaris. | a 31-year-old male who had been suffering from ichthyosis vulgaris developed hyperkeratosic lesions on the palms and soles and ungual alterations of both hands and feet. these lesions were resistant to topical corticosteroid and emollient cream treatments and were found to be caused by trichophyton rubrum. association of ichthyosis vulgaris and dermatophytosis--both very common disorders--is to our knowledge a very rare event. | 1992 | 1287487 |
| pattern of dermatophyte infection in singapore. | dermatophyte infection is the fourth commonest skin disorder seen in the national skin centre in singapore. a prospective study was carried out from june 1990 to march 1991 to determine the epidemiology and pattern of dermatophyte infections seen in this centre. two hundred patients who had a clinical diagnosis of dermatophyte infection and confirmed by direct microscopy were included into the study. cultures for dermatophyte were done on sabouraud's dextrose agar with chloramphenicol and cycloh ... | 1992 | 1295417 |
| inhibition of growth of dermatophytes by indian hair oils. | a survey on the use of hair oils for hair dressings by the indian population revealed that mustard oil is preferred by males and coconut oil by females. amla oil is used equally by both. these oils contain different percentages of various saturated and unsaturated fatty acids which largely determine their toxicity against dermatophytes. for microsporum canis, m. gypseum and trichophyton rubrum, amla oil was most toxic, followed by cantharidine and coconut oil, while trichophyton mentagrophytes w ... | 1992 | 1302812 |
| dermatophytosis due to trichophyton rubrum in northern greece during the decade 1981-1990. | during the years 1981-1990 trichophyton rubrum was the most frequent causative agent of dermatophytic infections in northern greece, especially in cases of tinea pedis, cruris, corporis, and unguium, as well as dermatophytosis of the hands. between sexes there was a prevalence in women in tinea pedis and toenail infections. men were particularly infected in the groin, the hands and the face. the chronic follicular dermatophytosis in the lower legs was also presented in women, but tinea corporis ... | 1992 | 1302814 |
| binding of trichophyton rubrum mannan to human monocytes in vitro. | we recently reported that the mannan component of trichophyton rubrum cell wall (trm) has an inhibitory influence on cell-mediated immune function in vitro. we now describe experiments designed to identify the target cell for this effect of trm. t. rubrum mannan labeled with fluorescein (fitc-trm) was incubated with peripheral blood mononuclear leukocytes, monocytes, or lymphocytes. binding and uptake of the fitc-trm were monitored by fluorescence microscopy and flow cytometry. approximately 10% ... | 1992 | 1317395 |
| efficacy and safety of itraconazole in the long-term treatment of onychomycosis. | sixty-one patients with a clinical diagnosis of onychomycosis in finger or toe nails were treated with itraconazole 100 mg/day or griseofulvin 500 mg/day for six to nine months. the infective causes were trichophyton rubrum, trichophyton mentagrophytes, or trichophyton violaceum, and in two cases candida albicans. a total of 27 finger and 390 toe nails were infected. statistically significant intragroup reductions from baseline symptom severity values were seen at endpoint (month 6 or 9) for bot ... | 1992 | 1324238 |
| mitochondrial dna sequence analysis of the cytochrome oxidase subunit i and ii genes, the atpase9 gene, the nadh dehydrogenase nd4l and nd5 gene complex, and the glutaminyl, methionyl and arginyl trna genes from trichophyton rubrum. | in this paper, we present the nucleotide sequence of a 5248 bp-long region of the mitochondrial (mt) genome of the dermatophyte trichophyton rubrum. this region which represents about 1/4 of the total mt genome of this species reveals a compact organization of genes including: the glutaminyl trna, the methionyl trna, the cytochrome oxidase subunit i gene, the arginyl trna, the mitochondrial version of the atpase subunit 9 gene, the cytochrome oxidase subunit ii gene and a part of the nadh dehydr ... | 1992 | 1326416 |
| the unexpectedly rapid response of fungal nail infection to short duration therapy. | to test our hypothesis that, by laying down a fungicidal barrier in the growing nail, a short course of antifungal therapy should be effective against onychomycosis, we treated 8 subjects with trichophyton rubrum nail infection with terbinafine 125 mg b.d. for 14 days. all but one patient showed marked improvement, and 80% of fingernails and 37% of toenails were clinically cured after 6 months. although this confirmed our prediction, the onset of response measured by outward movement of affected ... | 1992 | 1350399 |
| binding and uptake of trichophyton rubrum mannan by human epidermal keratinocytes: a time-course study. | trichophyton rubrum infects skin. this fungus or its products might affect the function of epidermal cells. we previously reported that t. rubrum mannan (trm) exhibits a suppressive effect on proliferation of human lymphocytes. the goal of the present study was to investigate the possibility of direct interaction of trm with cultured normal human epidermal keratinocytes (ek). mannan, a cell wall glycoprotein, was extracted from t. rubrum by precipitation with cetyltrimethylammonium bromide and c ... | 1992 | 1357884 |
| possible mechanisms of immune modulation in chronic dermatophytoses: an in vitro study. | it has been suggested that patients with chronic superficial trichophyton rubrum infection have defective cellular immunity to dermatophyte antigens. this may be due to a selective anergy to dermatophyte antigens or reflect the activity of dermatophyte-derived lymphocyte inhibitory factors. to explore these possibilities, we assessed lymphocyte transformation to a variety of recall antigens, including a cytoplasmic and exoantigen preparation of trichophyton rubrum in 15 patients with chronic der ... | 1992 | 1390167 |
| [preliminary data on dermatomycoses in ouagadougou (burkina faso)]. | this study is a contribution to a best knowledge of mycosis in burkina faso where the data concerning these diseases are very old. it has been focused on the clinical and mycological features of the dermoskeloton mycosis through the consultations at the two offices of dermatology in the city of ouagadougou. from april to october, 1990, 216 patients have been taken census of, and they have shown 265 lesions among which 143 mycosis of the skinfolds (54 p. cent), 45 onychomycosis (17 p. cent), 29 p ... | 1992 | 1406214 |
| forty four years of dermatophytes in a chicago clinic (1944-1988). | data are presented on 39,270 cultures taken over a 44 year span (1944-1988) at the university of chicago's dermatology clinic. in the mid 1940's microsporum audouinii accounted for 60-80% of isolates. it gradually decreased over the next two decades and disappeared altogether in the 1970's. trichophyton rubrum, rare in the 1940's accounted for over 60% of isolates in the mid-1960's only to be overtaken by t. tonsurans. this species, not isolated till the mid 1950's, became and remains the domina ... | 1992 | 1406904 |
| comparative efficacy and safety of amorolfine nail lacquer 2% versus 5% once weekly. | altogether 157 patients with onychomycosis affecting not more than 80% of the surface area of nail with intact lunula and matrix were treated once weekly for up to 6 months with amorolfine nail lacquer (2 or 5%) in a double-blind randomized design. clinical examinations were carried out before, monthly during, and 1 and 3 months after therapy. mycological examinations were performed before, 1 and 3 months after therapy. one hundred patients were evaluated. according to the overall assessment by ... | 1992 | 1458664 |
| the effect of sulconazole on the antigenic composition of two dermatophyte species. | trichophyton rubrum and trichophyton interdigitale have been grown in liquid culture in the presence of sulconazole. the antigenic activity of detergent extracts of intact organisms was analysed following sds-page and the probing of western blots with homologous antisera raised in rabbits and with sera from patients with dermatophyte infections. differences in protein-band patterns were noted; some bands present in control samples were absent in azole-treated samples and vice versa. these differ ... | 1992 | 1474985 |
| once-weekly oral doses of fluconazole 150 mg in the treatment of tinea corporis/cruris and cutaneous candidiasis. | ninety-five adult out-patients with tinea corporis and/or tinea cruris participated in a multicentre open non-comparative study investigating the safety and efficacy of 1-4 once-weekly doses of oral fluconazole 150 mg. trichophyton rubrum was isolated most frequently (67 of 86 mycologically evaluable patients). a mean of 2.6 doses of fluconazole was administered; patients infected with candida albicans or epidermophyton floccosum required an average of 2 doses compared to 3-4 doses in patients i ... | 1992 | 1486705 |
| once-weekly oral doses of fluconazole 150 mg in the treatment of tinea pedis. | seventy adult out-patients with tinea pedis participated in a multicentre open non-comparative study of the safety and efficacy of once-weekly doses of oral fluconazole 150 mg. a mean of 3 doses of fluconazole was administered; patients infected with candida required an average of 2 doses compared to 3-4 doses in patients infected with other organisms. clinical cure was obtained in 45 of 61 (74%) evaluable patients at the last post-treatment evaluation, with 15 patients being substantially impro ... | 1992 | 1486706 |
| isolation of dermatophytes from clinically normal sites in patients with tinea cruris. | sixty patients clinically suspected of tinea cruris were studied by collecting skin scrapings from the site of their lesions and six clinically normal sites including the thighs, scrotum, crural clefts, natal cleft and the web between their 4th and 5th toes. dermatophytes were detected in scrapings in 46 (77%) and by culture in 36 (60%) patients from lesions. trichophyton rubrum was isolated from 32 and epidermophyton floccosum from 4 patients. dermatophytes were also isolated with maximum isola ... | 1992 | 1494358 |
| ige antibodies to pityrosporum orbiculare and staphylococcus aureus in patients with very high serum total ige. | serum ige antibodies were detected with the radioallergosorbent test (rast) to a panel of allergens which included pityrosporum orbiculare, candida albicans, trichophyton rubrum, cladosporium herbarum, staphylococcus aureus, animal dander, deciduous tree pollens, grass pollens and foods in 81 consecutive patients with total ige greater than or equal to 3000 ku/l. data on atopic and infectious disease characteristics were collected by a questionnaire. ige antibody concentrations to p. orbiculare ... | 1992 | 1525694 |
| molecular evolution of the fungi: human pathogens. | the morphological, ecological, and clinical diversity among ascomycete fungi that are pathogenic to humans suggest that the potential for pathogenicity may have arisen multiple times within these higher fungi. we have obtained 18s ribosomal dna sequences from a diverse group of human pathogenic fungi in order to determine their evolutionary origins. the fungi studied include a skin pathogen that is confined to humans (trichophyton rubrum) and three systemic, facultative parasites that cause hist ... | 1992 | 1528111 |
| treatment of onychomycosis with terbinafine. | an open multicentre trial was conducted by 40 dermatologists in switzerland involving 188 patients with onychomycosis of either the toenails or fingernails. of these patients, 145 who had positive microscopy and culture of dermatophyte infection were evaluable: of the dermatophytes identified at the initial visit, 80% were trichophyton rubrum and 12.4% were t. mentagrophytes. only the most affected nail was evaluated during the observation period. daily dosage was 250 mg of terbinafine (lamisil) ... | 1992 | 1531928 |
| nail dust aerosols from onychomycotic toenails. part ii. clinical and serologic aspects. 1984. | the podiatric procedure of burring hyperkeratotic fungal infected toenails results in large quantities of nail dust aerosols. an extremely large percentage (31%) of podiatrists who were analyzed for immunoglobulin e (ige) by antibody radioimmunoassay were found to have abnormally high levels. incidence of precipitin antibodies to trichophyton rubrum in sera of those in practice from 0 to 15 years was 23%, and those in practice 16 years or more was 29%. in this study, podiatrists who were chronic ... | 1992 | 1532984 |
| [shifts in the species spectrum of mycoses in the netherlands from 1970-1990]. | a review is presented of yeast and mould infections occurring in humans in the netherlands. the occurrence of the dermatophytes trichophyton rubrum and t. mentagrophytes tends to increase, while microsporum canis and particularly epidermophyton floccosum have become less common. the yeast candida glabrata is particularly often involved in infections of the urinary tract. candida krusei, c. parapsilosis and c. tropicalis have become less significant. remarkable differences are found between the s ... | 1992 | 1557162 |