| [effect of dietary alpha-linolenic acid on the conversion of linoleic and gamma-linolenic acids (1-14c) into arachidonates in rats in vivo]. | the effects of alpha-linolenic acid (9-12-15 octadecadienoic) upon the conversion in vivo of [1-14c] linoleic acid and of [1-14c] gamma-linolenic acid into arachidonate have been studied in adult rats. the two tracers have been administered by stomach tubing and the amounts of [14c]-radioactivity incorporated into arachidonate in the liver, kidneys and whole rat have been measured 48 h later. three experiments have been carried out on rats fed on alpha-linolenic acid containing diets prior to th ... | 1978 | 84552 |
| the safety of rapeseed oil. | | 1978 | 101916 |
| [effects of hypobaric hypoxia and erucic acid on mitochondrial triglycerides in rat heart]. | at normal atmospheric pressure, an erucic acid-supplemented diet produces an increase of heart mitochondrial triglycerides. with the same quantity of erucic acid, hypoxia emphasizes the triglyceride overload in rat heart mitochondria. thus, hypoxia increases the risk caused by rapeseed-oil. in hypoxia or at normal atmospheric pressure, rapeseed-oil without erucic acid does not modify the level of mitochondrial triglycerides. | 1978 | 150928 |
| [researches on the physiopathologic effects of rapeseed oil with high and low erucic acid content]. | the physiopathological effects were studied of a common high erucic acid rapeseed oil as well as of janpol, a low erucic acid oil produced of a rapeseed variety selected in poland. its erucic acid content equals 2.8% of total fatty acids. the studies were carried out on white male wistar rats, 25 days old at the beginning of experiment. these animals were divided into 6 groups fed the diets in which 10 or 20% of kcal well supplied either by high erucic acid rapeseed oil, by janpol rapeseed oil, ... | 1978 | 153722 |
| [lipid overload induced in myocardial cells by vegetable oils. observation using electron microscopy]. | comparative studies were made to estimate the lipid overloading of myocardiac cells in rats fed by groups, for 3 and 6 days, one of the following dietary oils: peanut oil, maize oil, sunflower oi, soyabean oil, rapeseed-primor oil, rapeseed-canbra oil and rapeseed oil. | 1975 | 171096 |
| size of lipoprotein particles in the intestinal lymph of rats fed on corn oil, peanut oil, rapeseed oil or canbra oil. | | 1979 | 216957 |
| [nutritional and biological experiences on low-erucic acid rapeseed oil "janpol". studies on rats after ingestion of "janpol" oil and other edible fats]. | comprehensive investigations were carried out for establishing the biological and nutritional value of low erucic-acid rapeseed oil from a variety of rape called janpol selected in poland. the pathophysiological effects of janpol rapeseed oil were observed after giving it as the only source of fat in the diet or added in different proportions to other edible fats. in all cases the total amount of fat in the diet was 20 p. 100 kcal. the investigations were carried out on 78 young male wistar rats ... | 1978 | 220900 |
| metabolism of erucic acid in perfused rat liver: increased chain shortening after feeding partially hydrogenated marine oil and rapeseed oil. | | 1979 | 228147 |
| the effect of feeding rats with partially hydrogenated marine oil or rapeseed oil on the chain shortening of erucic acid in perfused heart. | 1. the metabolism of [14(-14)c]erucic acid and [u-14c]palmitic acid was studied in perfused hearts from rats fed diets containing hydrogenated marine oil, rapeseed oil or peanut oil for three weeks. 2. [14c]erucic acid was shortened to [14c]eicosenoic acid (20 : 1, n -- 9) and [14c]oleic acid (18 : 1, n -- 9) in perfused rat hearts from all diet groups. the rapeseed oil diet caused a three-fold increase and the marine oil diet a four-fold increase in the amount of chain-shortened products recove ... | 1979 | 228734 |
| ultrastructural alterations of the myocardium of rats fed rapeseed oils. | ultrastructural studies were conducted on the myocardium of rats fed corn oil, tower rso (0 . 88 per cent ea), 1788 rso (3 . 6 per cent ea) and target rso (38 . 9 per cent ea) supplemented diets for 18 weeks. cardiac myocytes of tower rso-fed rats showed some loosening of myofibrils and a slight increase in the number of mitochondria, few of which had lost their cristae. large intravascular lipid droplets were observed in the myocardium of rats fed the 1788 rso diet, as well as some small lipid ... | 1979 | 262600 |
| effects of edible oils on blood and arterial lipids in rats after one year's balanced normolipidic diet. | male sprague-dawley rats were fed during one year with diets containing 12% of one of the following fats: butter, sunflower oil, rapeseed oil, soybean oil, hydrogenated soybean oil, palm oil, canbra oil and arachid oil. total serum cholesterol was lower in the arachid, suflower and butter groups and higher in the palm and hydrogenated soybean groups (p less than 0.01); serum cholesterol esters were lower in the arachid, sunflower and soybean groups, but higher in the palm and hydrogenated soybea ... | 1977 | 267716 |
| nutritional evaluation of low-erucic-acid rapeseed oils. | detailed morphometric studies performed in heart tissue from swiss mice and wistar rats show that, in comparison with other edible oils, long-term feeding of the new rapeseed oils, poor in erucic acid, do not significantly affect the incidence of myocardial background lesions, in contrast to high-erucic-acid rapeseed oil. the strong predisposition of the sprague-dawley rat, however, to develop myocardial necrosis is re-emphasized. the factors underlying this particularity need further clarificat ... | 1978 | 277106 |
| effects of rapeseed oil compared to hydrogenated marine oil in rats. histopathological effects of erucic acid and isomers on the heart. | in a recent review on the role of fats in human nutrition vergroesen and gottenbos (1975) emphasize, that the presence of erucic acid isomers in hydrogenated marine oils (hmo) may constitute a toxicological problem as serious as erucic acid in rapeseed oil (rso). on the contrary christophersen et al. (1976) stress, that these fatty acids in hmo represent a minor toxicological problem, and that conclusions drawn from hmo to rso are questionable. preliminary studies at our institute indicate lipid ... | 1978 | 277125 |
| a comparison of fatty acids from high levels of docosenoic acids of rapeseed oil (erucic acid) and of partially hydrogenated fish oil (primarily cetoleic acid) in a non-human primate species in a short-term exploratory study. | | 1977 | 410406 |
| morphologic effects of dietary plant and animal lipids rich in docosenoic acids on heart and skeletal muscle of cynomolgus monkeys. | cynomolgi (macaca fascicularis) were fed diets containing 25% rapeseed oil (rso), partially hydrogenated herring oil (phho), or a 3:1 mixture of lard and corn oil as control for 4 months. the rso contained approximately 25% of the fatty acids as erucic acid; the phho contained a similar concentration of mainly cetoleic acid. the control diet did not include such fatty acids. at the time of necropsy, the rso- and phho-fed monkeys showed myocardial and skeletal muscle lipidosis. foci of mononuclea ... | 1978 | 415615 |
| effects of plant and animal lipids rich in docosenoic acids on the myocardium of cynomolgus monkeys. | cynomolgus monkeys (macaca fascicularis) were fed diets containing 25% rapeseed oil (rso), partially-hydrogenated herring oil (phho) or a 3:1 mixture of lard/corn oil as control (con) for 4 months. the rso contained approximately 25% of the fatty acids as erucic acid (cis-docos-13-enoic, 22:1w9) while the phho contained a similar concentration of mainly cetoleic acid (cis-docos-11-enoic, 22:1w11). the con contained no 22:1 acids. the monkeys developed the expected myocardial lipidosis, somewhat ... | 1978 | 416402 |
| effect of marine oil and rapeseed oil on composition of fatty acids in lipoprotein triacylglycerols from rat blood plasma and liver perfusate. | the fatty acid patterns of triacylglycerols (tg) from very low density lipoprotein (vldl) in blood plasma and liver-perfusate from rats fed partially hydrogenated marine oil or rapeseed oil were determined. in the plasma from rats fed rapeseed oil for three days and three weeks, there was a small but significant decrease in the percentage of 22:1 fatty acid from 17.2 to 11.2% with length of feeding. in liver-perfusate, the comparable decrease with dietary rapeseed oil was from 18.5 to 5.2%, and ... | 1979 | 423712 |
| growth, lipid metabolism and pathology of two strains of rats fed high fat diets. | studies were carried out on sprague-dawley (sd) and chester beatty (cb) rats to determine whether the difference in incidence of myocardial lesions can be related to dietary factors and parameters known to be affected in sd rats fed rapeseed oils. the two strains of young, male rats were fed diets which contained 20% by weight of either corn, lear (low erucic acid) or hear (high erucic acid rapeseed) oils for a period of up to 16 weeks. a significantly lower incidence of focal myocardial necrosi ... | 1979 | 430222 |
| effects of high and low erucic acid rapeseed oils on energy metabolism and mitochondrial function of the chick. | duplicate experiments were conducted to compare energy utilization, growth, cardiac mitochondrial oxidative phosphoryl,tion, and mitochondrial membrane fatty acid composition of chicks fed diets containing 20 parts of high erucic acid rapeseed oil (her), low erucic acid rapeseed oil (ler) or sunflower seed oil (sfo) for 24 days. chicks fed diets containing her deposited less fat and utilized energy less efficiently (kcal gained/kcal consumed) than chicks fed diets containing either ler or sfo. e ... | 1979 | 430239 |
| comparison of lipid status in the hearts of piglets and rats on short term feeding of marine oils and rapeseed oils. | a series of 4 experiments with piglets and one experiment with rats has been conducted to establish the cardiac lipid status of weanling (3 weeks old) male animals fed fats with different contents of docosenoic fatty acids. experimental fats were rapeseed oil (rso) (48.0% 22:1), refined fish oil (rfo) (14.6% 22:1), partially hydrogenated fish oil (phfo) (14.3% 22:1) and lard (0% 22:1) combined with sunflower seed oil (sfo) in different proportions in diets with 21% total fat. lipidosis could not ... | 1979 | 440026 |
| beneficial effect of zinc supplementation on reproduction in rats fed rapeseed protein concentrate. | three groups of 33 90-day-old female sprague-dawley rats were fed, ad libitum, the following diets for 2 weeks before breeding. diet 1 (d1) contained 20% protein from casein, diet 2 (d2) had the same level of protein from tower rapeseed (brassica napus) protein concontrate (rpc) and diet 3 (d3) was the same as d2 with a zinc supplement (70 mg/l) in the drinking water. from each group 6 animals were killed before breeding and 5-9 animals were killed at 1 and 2 weeks of gestation and post-partum. ... | 1979 | 440630 |
| beneficial effect of zinc supplementation on reproduction in rats red rapeseed protein concentrate. | three groups of 33 90-day-old female sprague-dawley rats were fed, ad libitum, the following diets for 2 weeks before breeding. diet 1 (d1) contained 20% protein from casein, diet 2 (d2) had the same level of protein from tower rapeseed (brassica napus) protein concontrate (rpc) and diet 3 (d3) was the same as d2 with a zinc supplement (70 mg/l) in the drinking water. from each group 6 animals were killed before breeding and 5--9 animals were killed at 1 and 2 weeks of gestation and post-partum. ... | 1979 | 440631 |
| nutritional properties of poppyseed oil relative to some other oils. | male wistar rats were fed a purified basal diet with 20% lard and corn oil (3:1), sunflower oil, poppyseed oil, low-erucic rapeseed oil from brassica napus, cultivar tower, or mixtures of these oils, for 1 or 26 weeks. none of the hearts exhibited lipidosis at 1 week. at 26 weeks, the level of serum triglycerides was higher in rats fed the mixture of lard and corn oil than in those fed only vegetable oil, and the incidence of cardiac necrosis and fibrosis was higher in rats fed the rapeseed oil ... | 1979 | 440636 |
| the stimulation of erucate metabolism in isolated rat hepatocytes by rapeseed oil and hydrogenated marine oil-containing diets. | 1. the metabolism of palmitate and especially of erucate was studied in hepatocytes isolated from rats fed for 3 weeks a diet containing peanut oil (diet, 1), rapeseed oil (diet 2) and partially hydrogenated marine oil (diet 3). 2. the metabolism of palmitate was not significantly influenced by the diet. the rapeseed oil diet caused 1.4 fold and 1.3 fold increase and marine oil diet 3 fold and 2.2 fold increase in the oxidation and chain-shortening respectively of [14-14c]erucic acid in isolated ... | 1979 | 465511 |
| the effect of clofibrate on heart and plasma lipids in rats fed a diet containing rapeseed oil. | the effect of clofibrate on heart and plasma lipids in rats fed a diet containing 30% of the calories as peanut oil (po) or rapeseed oil (rso) (42.7% erucic acid and 0.5% eicosenoic acid) was studied. a decrease of erucic acid content to one-third and concomitant increase in the content of 18:1, 16:1 and 16:0 fatty acids in plasma triacylglycerols were observed after administration of clofibrate to rats fed the rso-diet. it is suggested that these changes reflect the increased capacity of the li ... | 1979 | 481134 |
| electron microscopic investigation of the intestinal epithelial cells and the lipoprotein particles of lymph in rats after ingestion of peanut, canbra and rapeseed oil in the diet. | | 1979 | 533873 |
| effect of mustard oil, rapeseed oil & groundnut oil feeding on development of myocardial lipidosis & fibrosis in rats. | | 1979 | 544469 |
| lack of fatty acid specificity in the lipolysis of oligo and polyunsaturated triacylglycerols by milk lipoprotein lipase. | native soybean and rapeseed oils and native and rearranged cod liver and peanut oils were subjected to partial hydrolysis with milk lipoprotein lipase and the fatty acid composition and molecular association in the substrates and lipolysis products were determined. in both native and rearranged oils the lack of significant differences in the fatty acid composition and molecular association between the residual and total triacylglycerols suggested that all triacylglycerols were attacked by the li ... | 1977 | 558804 |
| the role of dietary long chain fatty acids in mitochondrial structure and function. effects on rat cardiac mitochondrial respiration. | to evaluate the effect of dietary rapeseed oils on cardiac mitochondrial function and metabolic conservation of energy, male weanling rats derived from the sprague-dawley strain were fed three rations containing either 15% (w/w) soybean oil, low erucic acid rapeseed oil or a high erucic acid rapeseed oil. cardiac mitochondria were isolated for measurement of mitochondrial respiratory functions. pyruvate and malate plus malonate or succinate plus amytal, or alpha-ketoglutarate and malate plus mal ... | 1978 | 563903 |
| time course changes in total lipid content and fatty acid distribution in various tissues of young chickens after feeding rapeseed oil or soybean oil. | 1. in chicks fed rations containing 15% rapeseed oil (rso) or soybean oil (sbo) a gradual increase in the lipid content of heart tissue was found from 1 to 10 days of age. the finding that feeding high levels of rso to chicks did not cause excessive accumulation of fat in cardiac tissue supports the contention that it is inappropriate to extrapolate from one species to another (e.g. from rats to humans) as has been done by some workers with respects to rso utilization. 2. inclusion of rso in the ... | 1978 | 564889 |
| [effect of various edible oils on the monoxygenases in liver of rats]. | 2 months old male rats were fed over a period of 10, 30 and 60 days a diet containing 1.20% sunflower oil, 2.10% sunflower oil and 10% rapeseed oil, 3.6% sunflower oil, 8% rapeseed iuk abd 6% soybean oil. the diets caused changes in the composition of the fatty acid of total lipids and in the activity of the monoxygenase in the liver. the level of the oleic acid in the livers of the 2nd and 3rd groups was elevated. the linolic acid level was elevated in all three groups, the level of the 1st gro ... | 1978 | 567745 |
| subacute toxicological evaluation of sclerotia of sclerotinia sclerotiorum in rats. | weanling wistar rats of both sexes were fed diets containing 0 (control), 1% and 5% ground sclerotia of sclerotinia sclerotiorum derived from infected rapeseed (brassica napus). body weight, feed consumption and clinical appearance were monitored over an 84-day period. blood samples were collected on days 41 and 84 and necropsies performed on day 84. weight gain and feed consumption were similar in the control and 1% groups. in the 5% group, weight gain was depressed, feed wastage was greater an ... | 1978 | 570444 |
| cardiopathogenicity of soybean oil and tower rapeseed oil triglycerides when fed to male rats. | the triglycerides of soybean oil were purified by molecular distillation and those of tower rapeseed oil by molecular distillation and adsorption chromatography. the original oils and the purified triglycerides were incorporated in semisynthetic diets at 20% by weight and fed for 16 weeks to weanling male sprague-dawley rats to compare the nutritional and pathological effects of the oils and their triglyceride fractions on rats. the study was carried out at two independent laboratories. no signi ... | 1979 | 573839 |
| erucic acid in rapeseed oil. | | 1977 | 590896 |
| productive performance and liver lesions in two strains of laying hens receiving two rapeseed meals. | a comparative study was conducted to determine the effect of two varieties of rapeseed meal at 10 and 20% levels in the diet on the productive performance, organ weights and liver lesions of two commercial strains of laying hens. the double-low (brassica napus 1788) rapeseed meal appeared to be superior to span meal (brassica campestris) at the 10% level in maintaining egg production, feed efficiency, thyroid weight and body weight gain. however at the 20% level the productive performance was de ... | 1977 | 611494 |
| a comparison of procedures to determine free fatty acids in rat heart. | the level of free fatty acids in intact tissues has been found to be low but is known to rise in proportion to the extent of autolysis. therefore, the high levels of free fatty acid reported in the cardiac lipids of rats fed rapeseed oil were reinvestigated using two different procedures for homogenization. quick freezing and pulverization at dry ice temperature followed by lipid extraction was found to give lower values of free fatty acids (200 microgram/g of wet heart tissue) than the more com ... | 1978 | 621434 |
| eicosenoic and docosenoic acid incorporation in serum lipoproteins in rats fed rapeseed oil. | rats were fed rapeseed oil rich in eicosenoic (20:1) and docosenoic (22:1) acids for 7 days, and the fatty acid composition of the lipid classes of serum and serum lipoproteins was determined. concentrations of 20:1 and 22:1 acids in the lipid classes were variable, especially among lipoproteins, and were a direct function of the alimentary state of the animal. the results suggest differences in the incorporation of the above acids among the major lipoprotein types and various lipid classes with ... | 1978 | 634044 |
| changes in fatty acid composition of cardiac mitochondrial phospholipids in rats fed rapeseed oil. | male wistar rats were fed rapeseed oil containing high or low levels or erucic acid for 20 weeks, and changes in the fatty acid composition of cardiac mitochondrial phospholipids were studied. treatment with rapeseed oil containing 46.2% erucic acid showed incorporation of 22:1 (5.6%) into isolated cardiolipin from heart mitochondria. after high or low (3.7%) erucic rapeseed oil feeding, linolenic acid was slightly incorporated into cardiolipin. moreover, both of these rapeseed oils induced a si ... | 1978 | 661516 |
| effects of cold stress on rats fed different levels of docosenoic acids. | male sprague-dawley rats, 4 weeks old, were subjected to an ambient temperature of 4 c for periods up to 24 days and fed a synthetic diet containing one of the following oils: peanut oil (po), rapeseed oil (ro), low erucic acid rapeseed oil (lo), and partially hydrogenated marine oil (ho), each at 20% w/w. a parallel experiment using the same oils was performed at room temperature (23 c). during cold stress, animals on the ro diet showed higher mortality than all other groups; all 20 animals in ... | 1978 | 692293 |
| histopathology of the heart from rats fed rapeseed oils. | the cardiopathogenicity of oils from new, low erucic acid (ea) rapeseed, brassica napus, cv tower (0.88 per cent ea) and brassica napus, cv 1788 (3.6 per cent ea) were tested on rats following 18 weeks of feeding. oil from brassica napus, cv target, with 38.9 per cent ea served as a positive control and corn oil as the negative control. tower and 1788 rapeseed oils showed noticeable cardiopathogenicity, and a few mild lesions were also noted in the corn oil group. the main pathological change wa ... | 1978 | 749084 |
| nutritional evaluation of low-glucosinolate rapeseed meals obtained by various processes. | defatted meals were prepared from two new varieties of rapeseed, the 'high-glucosinolate' variety, brassica napus, lesira, and the 'low-glucosinolate' variety, brassica napus, erglu, by each of the following processes: (1) defatting of the ground seed with hexane; (2) extraction of the myrosinase-deactivated ground seed with 70% aqueous acetone for the removal of glucosinolates followed by defatting with pure acetone, and (3) autolysis of the ground seed for the decomposition of glucosinolates f ... | 1979 | 759989 |
| alteration of the lipase activities of muscle, adipose tissue and liver by rapeseed oil feeding of rats. | feeding rapeseed oil, rich in erucic acid, for 4 days results in a significant increase of the lipoprotein lipase activities of heart and adipose tissue. the lipase activity of liver, which in earlier studies has been shown to be releasable by heparin perfusion, also increases by the dietary regimen. the increased lipoprotein lipase activity of heart may contribute to lipid accumulation in this organ. the higher intracellular lipid store probably results in higher (hormone-sensitive) tissue lipa ... | 1979 | 760798 |
| increased chain shortening of erucic acid in perfused heart from rats fed rapeseed oil. | | 1979 | 761613 |
| physiopathological effects of rapeseed oil: a review. | rapeseed oil has a growth retarding effect in animals. some investigators claim that the high content of erucic acid in rapeseed oil alone causes this effect, while others consider the low ratio saturated/monounsaturated fatty acids in rapeseed oil to be a contributory factor. normally erucic acid is not found or occurs in traces in body fat, but when the diet contains rapeseed oil erucic acid is found in depot fat, organ fat and milk fat. erucic acid is metabolized in vivo to oleic acid. the ef ... | 1975 | 766575 |
| [variations in the lipid and fatty acid composition of cardiac tissue during perfusion of hearts isolated from rats on a high colza oil diet]. | after perfusion, during one hour, of isolated working hearts extracted from rats fed (60 days) with diet containing 15% of rapeseed oil, we have found a decrease of triglycerides and phosphatidic-cardiolipin fractions, particularly of fractions containing erucic acid. in contrast with this finding, lipids and phospholipids of hearts from rat feed with peanut oil is not decreased and fatty acid composition slightly altered. | 1975 | 808289 |
| biochemical and histological effects of feeding thermally oxidized rapeseed oil and lard to rats. | four groups of weanling rats were fed semisynthetic diets containing 15 percent by weight of dietary fats for 28 days. two groups received thermally oxidized low-erucic acid rapeseed oil (ole) or lard (ola) and the other two groups received the respective fresh fats (fle, fla) as controls. average daily feed consumption and feed efficiency were not affected by either ole or ola, however final body weights were depressed by the ola in the diet. the relative heart weights and heart total lipids we ... | 1977 | 832196 |
| studies of the utilization of high and low erucic acid rapeseed oils by the chick. | experiments were conducted to compare energy utilization, growth and tissue composition of chicks fed diets containing 10 or 20 parts of either high erucic acid rapeseed oir 24 days. results showed that chicks fed diets containing 10 or 20 parts ler grew at the same rate, utilized energy just as efficiently, had similar heart to body weight ratios and levels of heart lipids equal to or less than chicks fed comparable diets containing sfo. the substitution of 10 or 20 parts her for an equienerget ... | 1977 | 833686 |
| changes in the acyl and alkenyl group composition of cardiac phospholipids in boars fed corn oil or rapeseed oil. | boars fed diets containing rapeseed oil for 8 weeks showed significantly higher levels of neutral lipids and similar levels of phospholipids, compared to those fed corn oil. erucic and eicosenoic acids were found to be high in ethanolamine phosphoglycerides, and in particular alkenyl acyl-ethanolamine phosphoglyceride. furthermore, both long chain monoenes were incorporated preferentially in position 2 of the choline and ethanolamine phosphoglycerides. the alkenyl group composition of the cardia ... | 1977 | 846298 |
| the effects of original and randomized rapseed oils containing high or very low levels of erucic acid on cardiac lipids and myocardial lesions in rats. | the nutritional status of the very lowerucate, rapseed oil, brassica napus var. 'tower,' was compared with that of the high-erucate oil, brassica napus var. 'target,' as well as with corn oil. the effect of randomization on the nutritional qualities of rapeseed oil was investigated as well. the feeding of diets containing the original and randomized 'tower' oil or the original 'target' oil, at the 20% level by weight, gave growth rates which were not significantly different from that for corn oi ... | 1977 | 846307 |
| changes in rat heart phospholipid composition after rapeseed oil feeding. | the influence of long duration rapeseed oil feeding with high or low levels of erucic acid has been investigated on rat heart phospholipids. the rats treated for 20 wk with rapeseed oil containing 46.2% erucic acid showed a twofold increase in the sphingomyelin content of the heart. treatment with primor rapeseed oil (3.7% erucic acid) for 20 wk did not modify phospholipid composition of rat heart. the fatty acid patterns of phosphatidylethanolamine and phosphatidylcholine were slightly influenc ... | 1977 | 846318 |
| monoethlenic c20 and c22 fatty acids in marine oil and rapeseed oil. studies on their oxidation and on their relative ability to inhibit palmitate oxidation in heart and liver mitochondria. | 1. carnitine esters of erucic acid (22:1 n-9 cis), cetoleic acid (22:1 n-11 cis), brassidic acid (22:1 n-9 trans), gadoleic acid (20:1 n-9 cis) and oleic acid (18:1 n-9 cis) have been compared as mitochondrial substrates and as inhibitors of palmitoylcarnitine oxidation in heart and liver mitochondria. 2. both the rate of intramitochondrial-coa acylation and the rate of beta-oxidation decreases as the chain length increases from c18 to c22. there are no significant differences among the three c2 ... | 1977 | 870057 |
| myocardial lesions in rats fed rapeseed oil. i. influence of strain of rats. | the influence of strain of rat on the development of myocardial lesions was investigated in an experiment which included two factors: strain (wistar, sherman, chester beatty (hooded), and sprague-dawley from two sources designated sprague-dawley a, sprague-dawley c) and diet (5% corn oil, 20% corn oil, and 20% brassica napus var. zephyr rapeseed oil). groups of 30 rats, housed 2 per cage, from each of three different strains of rats and groups of 10 rats, housed 2 per cage, from one strain of ra ... | 1977 | 871958 |
| myocardial lesions in rats fed rapeseed oil. ii. effects of castration. | the effects of castration on the incidence of myocardial lesions in rats were investigated in an experiment which included two factors: sex (entire males, castrated males, entire females and castrated (ovariohysterectomized) females) and diets (5% corn oil, 20% corn oil, and 20% brassica napus var. zephyr rapeseed oil). for 16 weeks, each of the 12 groups of 30 sprague-dawley rats, housed 2 per cage, were fed ad libitum the test oils incorporated in a semisynthetic diet. at each weighing, the me ... | 1977 | 871959 |
| carnitine effect on heart steatosis induced in rats by rapeseed oil. | myocardial triglyceride levels in rats fed a high erucic acid rapeseed oil diet for three days were five times higher than in controls. the incorporation of erucic acid and, to a lower extent, some unsaturated fatty acids was increased, as well as total cholesterol content, compared to controls. the presence of 5% carnitine in the diet partially prevented these effects. it is assumed that carnitine may be a rate limiting factor in the myocardial catabolism of unsaturated fatty acids and particul ... | 1977 | 881297 |
| high and low erucic acid rapeseed oil in the diet of lactating rats. | | 1977 | 896743 |
| [comparative physiological effects of partially hydrogenated herring oils and rapeseed oil in the rat. ii. very short-term and medium term effects on the lipids of heart, lever and adipose tissue]. | | 1977 | 907273 |
| [physiopathological effects or erucic acid-poor rapeseed oil on rat adrenal glands]. | the authors explored the influence of colza oils containing variable proportions of erucic acid ("sinus", containing about 15 p. 100 erucic acid and k-20-40 oil, containing 0,5 p. 100) on adrenal function in the rat. the assays were performed on white male wistar rats, aged 2.5 to 3 months. for a period of 6-10 weeks, groups of animals were maintained on diets containing 30 and 50 p. 100 of their caloric value as "sinus" oil, and on diets containing 30 p. 100 of their caloric value as "zero" oil ... | 1977 | 907275 |
| nutritional effects of partially hydrogenated low erucic rapeseed oils. | the incidence of cardiac lesions in male rats fed rapeseed oil (brassica campestris, cultivar "span") was lower with partially hydrogenated oil (iodine value 78) than withe the liquid oil which had been treated in various ways. another rapeseed oil (brassica napus, cultivar "tower") was similarly improved when hydrogenated to iodine value 76.6, but not at iodine value 97.1, as demonstrated in both sprague-dawley and wistar rats. the improved nutritional quality of hydrogenated oil appeared not t ... | 1977 | 916818 |
| electrocardiograms of male rats fed rapeseed oil. | frontal plane electrocardiograms (standard limb leads) were recorded on male sprague-dawley rats fed for 14 weeks on semisynthetic diets containing 20% (by weight) of brassica napus cv. tower or b. campestris cv. span rapeseed oil or fractions isolated from span rapeseed oil. control diets were rat chow or semisynthetic diets containing 20% (by weight) of either safflower oil or corn oil. the amplitude of the p, q, r, s, and t waves, the duration of the p wave, qrs complex, and p-r interval, and ... | 1977 | 922586 |
| the influence of dietary inositol on glyceride composition and synthesis in livers of rats fed different fats. | the effect of inositol supplementation on the composition and biosynthesis of glycerides in the livers of rats fed diets containing fats with differing fatty acid composition was investigated. the dietary fats employed in these studies included corn oil, tower rapeseed oil (rso), partially hydrogenated soybean oil (sbo), and tallow. no significant influence of inositol on hepatic triglyceride levels was found in animals fed corn oil and sbo whereas inositol deficiency caused a two-and four-fold ... | 1976 | 943478 |
| cardiopathogenicity of rapeseed oils and oil blends differing in erucic, linoleic, and linolenic acid content. | male wistar rats were fed semipurifed diets containing 20% fat for 25 weeks. ten different oils or oil blends were employed, including rapessed oils, simulated rapeseed-type oils, and modified rapeseed-type oils. safflower, soybean, and hydrogenated coconut oils served as control oils. histopathological examination of the cardiac tissue was conducted at the end of the study and an incidenceseverity rating assigned to the lesions induced by each fat. oils containing high levels of erucic acid (26 ... | 1976 | 948250 |
| mortality and production characteristics of laying chickens fed high- and low-erucic acid rapeseed oils. | laying pullets were fed a diet supplemented with three percent of either high-erucic acid rapeseed (hear) oil or low-erucic acid rapeseed (lear) oil for 39 weeks. egg production for the period was 78.8 and 80.1% by the birds fed the respective oils. average egg weights were 56.8 and 58.7 g. respectively. gains in body weight, liver weight and adrenal gland weight were similar with the two types of oil fed. feed consumption was similar for the two groups of birds. the efficiency of utilization of ... | 1976 | 951380 |
| [fatty acids in 80 brands of edible vegetable oil and in 14 brands of mayonnaise (author's transl)]. | the fatty acid patterns have been defined in 80 commonly used table oils chosen at random and of 14 brands of mayonnaise commercially available in west germany. in addition, sterols of the various mayonnaises were analysed. the oils could be grouped into 8 different categories: 12 oliver oils, 8 maize oils, 14 soya oils, 5 linseed oils, 22 sunflower oils, 3 safflower oils, 5 groundnut oils, and 8 rapeseed oils. as a result of the analyses, it is in almost every case a question of a pure variety ... | 1976 | 979069 |
| effect of nutrition in the rearing and laying phases on mortality and egg composition of crossbred layers. | crossbred pullets reared on a low plane of nutrition had a lower mortality rate due to marek's disease and lymphoid leucosis in the laying phase and had smaller livers with less fat than those reared on a high plane of nutrition. on the other hand, the addition of 0.06% methionine to the laying diet increased the incidence of deaths due to marek's disease and lymphoid leucosis. the spleen weight of birds fed the diet supplemented with methionine was greater than that of those fed the unsupplemen ... | 1976 | 985249 |
| cathodic stripping voltammetry of nanogram amounts of selenium in biological material. | a method is described to determine selenium in biological material, based on cathodic stripping voltammetry. following wet ashing, the selenium was extracted into benzene as the 3',4'-diaminophenylpiazselenol. the selenium was subsequently back-extracted into dilute acid for analysis. analyses of nbs bovine liver demonstrated that the method was capable of recovering 96+/-9% of the selenium present. the detection limit and working range were 3 ng/g and 0-10,000 ng/g, respectively. the method was ... | 1976 | 993175 |
| effects of rapeseed oil on fatty acid oxidation and lipid levels in rat heart and liver. | the comparative rates of oxidation of erucic and oleic acids and of their coa esters were studied in heart and liver mitochondria of rats fed a standard diet or semisynthetic diets containing 25% of the calories as either rapeseed oil (46.6% erucic and 10.4% eicosenoic acid) or olive oil, for a period of 5 months. the long exposure to the diet containing 25% rapeseed oil did not alter the oxidative activity of mitochondria and did not induce morphological changes in the heart. it is confirmed th ... | 1976 | 994756 |
| pathological changes in chickens, ducks and turkeys fed high levels of rapeseed oil. | rations containing 25% of either regular rapeseed oil (36% erucic acid), oro rapeseed oil (1.9% erucic acid), soybean oil or a mixture of lard and corn oil were fed to chickens, ducks and turkeys. the regular rapeseed oil ration caused growth depression, increased feed conversion and anemia in all species. all the ducks and some of the chickens fed the regular rapeseed oil ration died. these dead birds were affected with hydropericardium and ascites. no deaths in the turkeys could be attributed ... | 1976 | 1000400 |
| [influence of rapeseed oil feeding on morphology and oxidative properties of mitochondria isolated from the rat heart]. | mitochondria from heart of rats fed a diet rich in rapeseed oil for two months from weaning, oxidized oleic acid a little better than those from animals fed a control diet containing peanut oil; but their activity decreased much more in presence of potassium cyanide which is an oxidation inhibitor. when observed by electronic microscopy, mitochondria from heart of rats fed rapeseed oil were more mumerous and more mitochondria of great size were encountered as compared with control rats. biochemi ... | 1976 | 1029423 |
| [comparative physiological effects of partially hydrogenated herring and rapeseed oils in the rat. 1. mean-term effects on growth, organ weights and heart histology]. | two partially hydrogenated herring oils, containing 15% or 30% of c 22: 1, supplemented or not with linoleic (maize oil), have been fed for 16 weeks to growing rats (15% by weight in the diet), and their effects have been compared to those of peanut oil (controls), and to those of 2 mixtures of rapeseed oil and peanut oil having similar c 22:1 contents (15% and 30%). on the basis of equal amounts of ingested food, the growth of the rats is lower with herring and rapeseed oil than with peanut oil ... | 1976 | 1029425 |
| [influence of rapeseed oil on lipoprotein lipase activity in pigs (author's transl)]. | toxic activities in various animal species have shown for rapeseed oil. in this paper the influence of this oil on lipoprotein lipase activity of heart, liver and lung of pigs has been examined. the animals were fed with rapeseed oil with 40% erucic acid for 7, 15, 20 and 40 days. the control animals received olive oil. the results have shown a slight increase in the lipoprotein lipase activity in the heart of the pig after 20 days with rapeseed oil. in the liver this increase is particularly la ... | 1976 | 1037418 |
| [adaptation to a rapeseed oil enriched diet as shown by the mitochondrial oxidation rate in the heart (author's transl)]. | 40 wistar rats were divided into two groups which had been fed one year earlier a diet in which 30% of the caloric intake consisted of rapeseed oil and peanut oil respectively. both groups were then fed a diet of 30% peanut oil for five months and then fed a normal diet for seven months. at this time each of the two main groups was subdivided into four smaller groups, each group receiving a different diet: one of 25% rapeseed oil, one of 25% peanut oil, one of 25% butter, and one internal contro ... | 1976 | 1037419 |
| morphological effects of rapeseed oil in rats. i. short-term studies. | light microscopy of paraffin embedded and frozen sections, supplemented with electron microscopy, was performed on the heart muscle of young rats fed rapeseed oil in short-term experiments. it was confirmed that high levels of rapeseed oil, which contains erucic acid, produce severe lipoidosis of the heart muscle fibres within 10 days. an attempt was made to find out the lowest level of erucic acid in the rat diet to give rise to pathological fatty accumulation. several frozen sections from each ... | 1975 | 1062116 |
| morphological effects of rapeseed oil in rats. ii. long-term studies. | in long-term studies covering up to 160 days young sprague-dawley rats were fed diets containing 40 cal% of fat. the fat component consisted of either conventional rapeseed oil, or canadian rapeseed oil low in erucic acid, or arachis oil. myocardial fatty accumulation was demonstrated in light microscopic studies throughout the experiments in rats fed conventional rapeseed oil, but the number of fat droplets decreased with time. the controls fed arachis oil showed no fatty accumulation. in the r ... | 1975 | 1062117 |
| morphological effects of rapeseed oil in rats. iii. studies in germ-free rats. | the morphological effects on the myocardium of feeding rapeseed oil were compared in conventional and germ-free rats in short-term experiments (10 days). it was concluded that the fatty accumulation in the heart muscle cells occurring in rats fed rapeseed oil was not influenced by the presence or absence of a normal intestinal flora. in long-term experiments (80 days) under similar conditions, the myocardial effects of feeding germ-free rats with conventional rapeseed oil, rapeseed oil from the ... | 1975 | 1062118 |
| electrocardiogram and renal concentrating capacity in rats fed a diet containing rapeseed oil. | the functional effects of a diet containing rapeseed oil (40% of total energy intake) were studied in rats, starting at age 28 days. there were no effects on the electrocardiogram in spite of morphological changes in the myocardium. in 10 female rats the urine osmolality following 16 hours of dehydration was approximately 20% lower than in 10 control rats during the 9th, 10th and 20th week of the experiment. it is suggested that erucic acid in the rapeseed oil inhibits beta-oxidation of fatty ac ... | 1975 | 1062119 |
| observations on lipid composition with particular reference to cardiolipin of rat heart after feeding rapeseed oil. | the influence of dietary rapeseed oil on the lipid classes and fatty acid pattern of rat heart homogenate and mitochondria has been investigated after feeding a diet with 9.8 weight- % erucic acid for 10 days and 1.4 and 2.6% erucic acid for 28 days. the rats treated with 9.8% erucic acid showed a significant increase in the triglycerides of the heart mitochondria. this tendency was much less pronounced in rats treated with 1.4 resp. 2.6% erucic acid. these results confirm those of other investi ... | 1975 | 1062120 |
| effect of hydrogen peroxide treatment on the nutritional quality of rapeseed flour fed to weanling rats. | the effect of treating rapeseed flours with hydrogen peroxide on the glucosinolate content and nutritional value of the protein was examined. four flours were prepared from target variety rapeseed (brassica napus) by dehulling and defatting the seed (sample rf), by heat treating and water washing the dehulled seed prior to defatting (sample wwrf), and by treating a part of samples rf and wwrf with solutions of 7 and 3% hydrogen peroxide, respectively. chemical analysis showed that the hydrogen p ... | 1975 | 1117343 |
| erucic acid metabolism by rat heart preparations. | rat heart preparations metabolized erucic acid at much slower rates than palmitic acid. this applied for activation reaction, for the conversion of acyl-coa to acylcarnitine, and for the utilization of acyl group for oxidation. as compared to palmityl-coa, erucyl-coa exhibited a lower affinity for carnitine palmityltransferase (ec 2.3.1.23), the respective apparent michaelis constants were 43 and 83 mum. presence of erucyl-coa or erucyl-carnitine slowed the mitochondrial oxidation of palmityl gr ... | 1975 | 1134221 |
| thiocyanate ion formation in rapeseed meals. | meal prepared from unheated rapeseed (brassica napus cv. zephyr) showed the presence of t,iocyanate ion, while meal from heated seed of the same cultivar did not show detectable amounts. unheated seed meal on autolysis, and heated seed meal on incubation with thioglucosidase, yielded increased amounts of thiocyanate ion. various commercial rapeseed meals showed the presence of t,iocyanate ion only after enzyme incubation. low glucosinolate, cv. bronowski, and higher glucosinolate, cv. zephyr on ... | 1975 | 1139401 |
| influence of rapeseed oil feeding on the lipase activities of rat heart. | | 1975 | 1147953 |
| failure of dietary erucic acid to impair oxidative capacity or apt production of rat heart mitochondria isolated under controlled conditions. | 1. male, 8-week old rats were fed purina rat chow for semisynthetic diets containing 20% by weight of rapeseed oil or corn oil for 3 days. 2. the hearts from the animals fed the three diets were analyzed for total lipid, phospholipid, free fatty acids, cholesterol esters, tri-, di- and monoacylglyerols. there was a seven-fold increase in the levels of triacylglycerols in the hearts of rats fed rapeseed oil diet compared to the levels in the hearts of animals fed the other two diets. smaller incr ... | 1975 | 1148251 |
| cardiac lesions in rats fed rapeseed oils. | fully refined rapeseed oils containing different amounts of erucic acid (1.6%, 4.3% and 22.3%) were fed, at 20% by weight of diet, to weanling male and female sprague-dawley rats for periods up to 112 days. transient myocardial lipidosis characterized by accumulation of fat droplets in myocardial fibers was marked in male and female rats fed oxidized and unoxidized rapeseed oil containing 22.3% erucic acid, moderate with rapeseed oil containing 4.3% erucic acid and very slight in rats fed rapese ... | 1975 | 1170010 |
| the effects of high and low erucic acid rapeseed oils in diets for rats. | fully refined rapessed oils of high (regular rapeseed oil, b. campestris) and low erucic acid content (span oil, b. campestris; commercially hydrogenated span oil and zephyr oil, b. napus) and soybean oil were fed to male and female sprague-dawley rats at a level of 15% by weight in the diet. in the first experiment, 5 male and 5 female rats per treatment were housed individually, whereas in the second experiment 5 male or 5 female rats per treatment were housed in groups of five. body weight ga ... | 1975 | 1172494 |
| brassica campestris var. span: ii. cardiopathogenicity of fractions isolated from span rapeseed oil when fed to male rats. | rapeseed oils low in erucic acid caused myocardial lesions when fed to weanling male rats for 16 weeks. the cardiopathogenic properties appear to be associated with the triglycerides of the oil, and not to nontriglyceride components present in fully refined rapeseed oil. cardiac lipid analysis confirmed that erucic acid accumulation was proportional to the concentration of this acid in the diet. | 1975 | 1177663 |
| myocardial lesions induced by rapeseed oil-rich diet in the rat: ultrastructural aspects. | rats were fed a diet containing 15 g% of rapeseed oil rich in erucic acid (55%). at different stages of the experiment, the hearts were examined in the electron microscope and planimetric studies were performed, with special attention to lipid accumulation and mitochondrial mass. the already known data concerning the early appearance and reversibility of the intracellular lipidosis, the delay (2 to 3 months) in the occurrence of the cellular lesions, and the lack of correlation between the degre ... | 1975 | 1197899 |
| fatty haemorrhagic liver syndrome in laying hens on diets supplemented with rapeseed products. | livers of laying hens of hy-line no 934e on low erucic acid rapeseed meals and rapeseed oil were studied. gross lesions in the livers of hens on experimental diets were moderate to severe fatty degeneration, focal necrosis and moderate to severe haemorrhage. histological examination revealed oedematous foci and lysis of hepatocytes along with large amounts of lipid droplets in the necrotic lesions. necrotic lesions were not always associated with large haemorrhages. connective tissue infiltratio ... | 1975 | 1215683 |
| [effect of alcohol on the metabolic conversion of 14c erucic acid in the liver of rats receiving rapeseed or peanut oil]. | the effects of addition of ethanol to diets containing rapeseed or ground nut oil on the metabolic conversions of 14 14c erucic and 9-10 3h oleic acid were studied in the rat liver. 1. whatever the diet more 14c than 3h radioactivity was recovered in liver lipids 2 and 19 hours after injection of labelled fatty acids. ethanol has little effect on this incorporation. 2. only small amounts of 3h oleic acid were converted. 3. in all cases, the metabolic conversion of erucic acid was identical: the ... | 1975 | 1221113 |
| effect of exercise on the lipid content, lipid fatty acid composition and morphology of myocardial and skeletal muscles in rat. | the effect of exercise on the morphology of the myocardial and skeletal muscle, total lipid content and lipid fatty acid composition was checked in rats fed a rapeseed oil-containing diet. the graded exercise was found to reduce the growth rate of animals. myocardial fatty degeneration was less intense and erucic acid content lower in trained rats fed a diet with 50% kcal of rapessed oil than the untrained ones. the opposite was true when rapeseed oil supplied 30% of calories. histiocytic granul ... | 1975 | 1223812 |
| ultrastructure of rat myocardium after feeding a diet with low--erucic acid rapeseed oil. | electron microscopy was applied to study the myocardium of rats fed a diet with sunflower oil (group i), low-erucic acid rapeseed oil (group ii), or high-erucic acid rapeseed oil (group iii). the most severe lesions were found in group iii. the rats fed sunflower oil showed slight lesions in the form of dilated channels of endoplasmic reticulum and the presence of a few lipid droplets. similar abnormalities were found in group ii, they were followed, however, after four and eight weeks of experi ... | 1975 | 1223813 |
| [effect of dietary magnesium levels on cardiac lesions in rats fed a diet rich in rapeseed oil]. | cardiac lesions (histiocyte infiltration and fibrosis) obtained in rats fed rapeseed oil and 3 magnesium levels (high, low and normal) during 30 or 50 days are quantified by their size. correspondence factorial analysis is used to compare the results. after 30 days, less cardiac lesions of histiocyte infiltration or fibrosis appear with rats fed a diet high in both rapeseed oil and magnesium than with normal or low magnesium diet. after 50 days, cardiopathogenic effects are less severe with norm ... | 1975 | 1226266 |
| [effects of rapeseed oil on production of corticosterone by rats subjected to stresses (physical effort, cold]. | investigations were carried out on male wistar rats from an own animal farm of the institute of food and nutrition. the animals were kept on two types of diet containing 50 p. 100 of calories from rapeseed or sunflower oil. the investigations on the effect of rapeseed oil on functional changes of rat adrenals in animals exposed to graded physical exercise were performed on 40 rats aged 3.5 months at the beginning of the experiment. the animals were divided into two groups and were given during 6 ... | 1975 | 1227368 |
| [short term comparative study of effects of n-9 trans-docosenoic (brassidic) acid and n-9, cis-docosenoic (erucic) acid on the cardiac lipids of weanling rats]. | cardiac lipids (triglycerides and phospholipids) of weanling rats fed diets containing 15% by weight of rapeseed oil (rso), hydrogenated rapeseed oil (hrso), trierucin (te) or tribassidin (tb) were analyzed after 3 and 7 days of feeding. the amount of c22:1 was made equal in the 4 diets. trans-isomers of erucic acid found in hrso and tb do not cause as high an accumulation of lipids and docosenoic acids in the heart as erucic acid. digestibility of brassidic acid (46%) is lower than that or eruc ... | 1975 | 1230664 |
| nutritive value of rapeseed meals and rapeseed protein isolates. | defatted meals of two new varieties of rapeseed, brassica napus, erglu and lesira, and protein isolates prepared therefrom, were fed to chicks that had been depleted of their embryonic protein reserve. first, the animals were fed at a 12% protein level, half of it from rapeseed meal, or a rapeseed protein isolate and, subsequently, at a 20% level, all of it from rapeseed products. feed consumption, weight gain and protein efficiency ratio revealed better performance of the protein isolates as co ... | 1975 | 1230667 |
| lipid changes in tissues of young boars fed rapeseed oil or corn oil. | fully refined rapeseed oil, brassica campestris var. arlo plus echo, and corn oil were fed at 20% by weight of a basal diet to young yorkshire boars. a serial slaughter technique was employed whereby 3 boars from each dietary treatment were killed at 0,1,2,3,4 and 8 weeks of the experiment. the fatty acid profiles of heart, liver, adrenals and testes lipids were investigated. the typical fatty acids of rapeseed oil, erucic and eicosenoic acids, were incorporated at different levels into the tiss ... | 1975 | 1232599 |
| [effect of the quality of various vegetable oil emulsions on phagocytotic activity of the reticuloendothelial system in the rat]. | in the liver, reticuloendothelial cells make up 35 p. 100 of the total cellular population. the characterization of the reticuloendothelial system (res) is its phagocytic activity. certain fatty acids and lipids produce stimulation or depression of phagocytic function. in the present study, the phagocytic activity of the res has been evaluated 3 days after oral (15 g/kg) and intravenous (1, 5 g/kg) treatments of male rats with emulsions of peanut, canbra, soyabean, olive and rapeseed oils. the d ... | 1975 | 1241257 |
| investigations on rapeseed oil toxicology. | a series of investigations on humans and mice, performed in this laboratory in the years 1973-74 is presented. to assess the exposure levels of the italian population to rapeseed oil ingestion, the serum of 70 apparently healthy railway workers, as well as the adipose tissue and myocardium of 16 subjects deceased for different causes were analyzed, with a gas chromatographic method, to ascertain if erucic acid or its metabolites were present. 40 out of 70 subjects had measurable erucic acid in t ... | 1975 | 1243051 |
| [rapeseed oil: nutritional aspects and safety considerations (author's transl)]. | in this review data are reported on the effects of rapeseed oil feeding to several animal species (mice, pigs, rats, guinea pigs, ducklings, chickens, turkeys) with particular regard to its nutritional value as compared to other vegetable fats, and to physiological and pathological modifications on different organs and tissues, namely: gonads, adrenals, thyroid, liver, myocardium. finally, the results obtained after administration of regular rapeseed oil (i.e. with high levels of erucic acid) ar ... | 1975 | 1243957 |
| effect of cold stress on rapeseed oil fed rats. | no mortality was observed in 6 week old male sprague-dawley rats subjected to cold at 4 c for 3 weeks and fed either a control diet (chow) or a semisynthetic diet containing 20% by wt rapeseed oil high in erucic acid (23.6%). all rats fed the chow diet and 17 of 20 rats fed the rapeseed oil-containing diet survived 4 weeks in the same environment. three rats on the latter diet died of self-mutilation. marked myocardial lipidosis as well as a large acumulation of 20:1 and 22:1 was observed in the ... | 1976 | 1250067 |
| relationship between erucic acid and myocardial changes in male rats. | the back and belly fat of pigs fed a diet containing 20% by wt rapeseed oil (22% erucic acid) for 16 weeks was rendered into oil. this rendered pig fat, which contained 5.6% erucic acid, was fed to male rats in three separate experiments at 20% by wt of the diet for 16 weeks. in experiment i rendered pig fat was compared only to brassica campestris var. span rapeseed oil containing 4.8% erucic acid. in experiments ii and iii, rendered pig fat was compared to commercial lard containing 0.2% docos ... | 1976 | 1250074 |
| the development of dermal lesions and alopecia in male rats fed rapeseed oil. | for 8 weeks 10 male weanling sprague-dawley rats were fed a semisynthetic diet containing by weight either 20% corn oil or rapeseed oils containing different amounts of erucic acid (brassica napus var. zephyr, 0.6%; b. napus var. oro, 1.8%; b. campestris var. span, 4.8%; or b. campestris var. echo and arlo, i.e., regular rapeseed oil, 23.6%). at 4-5 weeks after the experiment began, rats receiving the diets containing rapeseed oil showed evidence of alopecia and developed scaly, hemorrhagic, and ... | 1976 | 1260511 |