| glycosides of magnolia. ii. structural elucidation of magnolidin. | magnolidin, the major glycoside of magnolia grandiflora l. consists of two moles of rhamnose, and each of glucose, caffeic acid and 3,4-dihydroxyphenethanol. based on degradative and spectroscopic evidence, a structure is proposed for magnolidin as one of two possible alternatives which differ with respect to the position occupied by the o-caffeyl unit. | 1975 | 52816 |
| isolation and characterization of the sesquiterpene lactones costunolide, parthenolide, costunolide diepoxide, santamarine, and reynosin from magnolia grandiflora l. | the germacranolide sesquiterpene lactones costunolide, parthenolide, and costunolide diepoxide were isolated from the leaves of magnolia grandiflora l. costunolide diepoxide might be, at least in part, an artifact derived from air oxidation of parthenolide. the root bark yielded only costunolide together with the two eudesmanolides, santamarine and reynosin. in an attempt to synthesize costunolide diepoxide, the action of m-chloroperbenzoic acid on parthenolide and on costunolide was studied. th ... | 1978 | 641720 |
| glycosides of magnolia grandiflora. part i: isolation of three crystalline glycosides. | | 1975 | 1161874 |
| a simple technique for removing plant polysaccharide contaminants from dna. | a survey of the inhibitory effects of various plant polysaccharides on dna restrictions (hindiii and ecori) revealed that neutral polysaccharides (arabino-galactan, dextran, gum guar, gum locust bean, beta-glucan, inulin, laminaran, mannan and starch) were not very inhibitory. in contrast, acidic polysaccharides (carrageenan, dextran sulfate, gum ghatti, gum karaya, pectin and xylan) were very inhibitory, even at low concentrations. the elutip-d (rpc-5 type resin) was evaluated for removal of th ... | 1991 | 2059438 |
| magnolia grandiflora dermatitis. | a patient is described who had allergies to several sesquiterpene lactone-containing plants, but the reaction to magnolia grandiflora was extremely severe. the condition was a chronic lichenified dermatitis that was unresponsive to treatment but cleared with protective measures. primary allergy to magnolia is rarely reported, even though some studies of cross-reactivity suggest that sensitivity is far from rare. | 1990 | 2137402 |
| tumor inhibitory agent from magnolia grandiflora (magnoliaceae). i. parthenolide. | | 1973 | 4686424 |
| [studies on the alkaloids of magnoliaceous plants. 38. alkaloids of magnolia grandiflora linn]. | | 1967 | 5627439 |
| constitutents of magnolia grandiflora. iii. toxic principle of the wood. | the alcoholic extract of the wood of magnolia grandiflora exhibited toxicity to mice when injected by the ip route. the toxic principle was found to be a phenolic quaternary alkaloid and was obtained as a colorless crystalline solid. analytical and spectral data showed that it was identical with menisperine (also called chakranine and isocorydinium cation) which has not been previously isolated from the genus magnolia. | 1982 | 7119806 |
| helical, motile mycoplasmas associated with flowers and honey bees in california. | spiroplasmas were cultured from nonsurface-sterilized flowers of magnolia tree (magnolia grandiflora l.) and tulip tree (liriodendron tulipfera l.) in alameda, solano, and yolo counties in california. spiroplasmas were also isolated from honey bees (apis mellifera l.) collected in the vicinity of davis and berkeley, ca. most of the isolates grew relatively slowly at 31 or 37 degrees c reaching maximum population at 31 degrees c in 8-10 days. the flower isolates were serologically indistinguishab ... | 1981 | 7214240 |
| antimicrobial activity of phenolic constituents of magnolia grandiflora l. | three phenolic constituents of magnolia grandiflora l. were shown to possess significant antimicrobial activity using an agar well diffusion assay. magnolol, honokiol, and 3.5'-diallyl-2'-hydroxy-4-methoxybiphenyl exhibited significant activity against gram-positive and acid-fast bacteria and fungi. the minimum inhibitory concentrations were determined for each compound using a twofold serial dilution assay. | 1981 | 7310672 |
| pharmacological screening of the aqueous extracts of magnolia grandiflora l. | preliminary screening studies of the aqueous extracts of flowers and leaves of magnolia grandiflora l. were carried out on different animal models in an attempt to confirm their effects on the cardiovascular system, in view of the wide use of this plant in traditional mexican medicine. | 1980 | 7469654 |
| rna editing in the cox3 mrna of magnolia is more extensive than in other dicot or monocot plants. | the magnoliaceae are discussed as one of the key species at the root of the flowering plants. to obtain molecular information for one of these phylogenetically interesting plant species, we determined genomic and cdna sequences of the mitochondrial cox3 gene in magnolia grandiflora. twenty-two rna editing events are identified to alter cytidines in the mrna to uridines, all but one of which change the encoded amino acid identity. rna editing in the cox3 coding region is thus more frequent in mag ... | 1996 | 8688456 |
| anticonvulsant effects of magnolia grandiflora l. in the rat. | the ethyl ether (ee) and hydroalcoholic extract (he) of magnolia grandiflora l. (magnoliaceae) seeds, a popular plant utilized in the mexican traditional medicine because of its antispasmodic as well as other reported pharmacological effects, were studied in adult male wistar rats. ee and he orally administered in a single dose of 250 mg/kg (calculated on lipidic base) and 200 mg/kg, exhibited abolition of the extensor reflex of maximal electric induced-seizure test in 50 and 40% of the experime ... | 1998 | 9683345 |
| reynosin from sassurea lappa as inhibitor on cinc-1 induction in lps-stimulated nrk-52e cells. | an inhibitor on cinc-1 (cytokine-induced neutrophil chemoattractant-1) induction in lps-stimulated rat kidney epithelioid nrk-52e cells was purified from the roots of sassurea lappa clarke, a herbal medicine used in korean traditional prescriptions for gastric intestinal diseases by a variety of column chromatographic procedures. the inhibitor was identified as reynosin, a sesquiterpene lactone isolated and characterized previously from ambrosia confertiflora dc., and magnolia grandiflora l. rey ... | 1998 | 9690347 |
| [digitalic therapy. historical outline]. | the action of medical drugs obtained from many vegetables aroused a great interest of naturalists and physicians in all time. moreover, it was always required that those persons destined to medical practice have a good knowledge of botany. among the medicinal plants utilized by ancient peoples of the anahuac, yoloxochitl or heart flower (talauma mexicana) is mentioned, which seems to have a digitalis-like action. research in our century demonstrated a positive inotropic and bradycardic effect of ... | 2000 | 11080935 |
| a sesquiterpene lactone, costunolide, from magnolia grandiflora inhibits nf-kappa b by targeting i kappa b phosphorylation. | a sesquiterpene lactone, costunolide (ctn), was identified from magnolia grandiflora together with parthenolide (ptn) by its strong inhibition of lps-induced nf-kappa b activation. ctn, which showed more potent inhibition than ptn in the nf-kappa b activation, strongly suppressed nitric oxide (no) production in lps-stimulated raw 264.7 cells. rt-pcr and western blot analyses demonstrated that ctn suppressed the expression of inos mrna and protein in a dose-dependent manner. ctn also significantl ... | 2001 | 11301852 |
| two new germacranolides from magnolia grandiflora. | two new sesquiterpenoids, 4,5-epoxy-13-methoxy-1(10)-germacren-12,6-olide and 4,5-epoxy-13-acetoxy-1(10)-germacren-12,6-olide, were isolated from the leaves of magnolia grandiflora, together with six known compounds, 2alpha-hydroxy-dihydroparthenolide, parthenolide, costunolide, syringaresinol, (+) medioresinol and 6,7-dimethoxycoumarin. the structures of the new compounds were elucidated on the basis of spectroscopic methods and x-ray diffraction. | 2001 | 11407820 |
| sesquiterpenoids from magnolia grandiflora. | three new sesquiterpenoids were obtained from the leaves of magnolia grandiflora l. their structures were determined as 6 alpha,11-dihydroxy-12,13-diacetoxyelem-1,3-diene, 4 alpha,6 alpha,10 alpha-trihydroxy-13-acetoxyguaia-11-ene, and 12,13-diacetoxyguaia-4 alpha,6 alpha,10 alpha,11-tetraol on the basis of spectral evidence. in addition, the known sesquiterpenoid magnograndiolide was also obtained. | 2001 | 11458454 |
| honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo. | natural products comprise a major source of small molecular weight angiogenesis inhibitors. we have used the transformed endothelial cell line svr as an effective screen of natural product extracts to isolate anti-angiogenesis and anti-tumor compounds. aqueous extracts of magnolia grandiflora exhibit potent activity in our svr proliferation assays. we found that the small molecular weight compound honokiol is the active principle of magnolia extract. honokiol exhibited potent anti-proliferative ... | 2003 | 12816951 |
| the outer integument and funicular outgrowth complex in the ovule of magnolia grandiflora (magnoliaceae). | the development of the outer integument and funicular outgrowth in the ovule of magnolia grandiflora was examined by microtomy and scanning electron microscopy to reveal the morphology and evolution of the outer integument, a novel angiosperm structure. early in development the outer integument is semiannular, decurrent to the lateral sides of the funiculus, and extends downwards beyond the funicular outgrowth that forms in the gap of the outer integument, and is transverse to the funiculus. the ... | 2003 | 12836041 |
| [liquid extract of magnolia grandiflora as a new drug]. | | 1953 | 13051144 |
| studies on the alkaloids of magnoliaceous plants. xii. alkaloids of magnolia grandiflora l. (1). | | 1954 | 14356872 |
| studies on the alkaloids of magnoliaceous plants. xiii. alkaloids of magnolia grandiflora l. (2). | | 1954 | 14356873 |
| studies on the alkaloids of magnoliaceous plants. xiv. alkaloids of magnolia grandiflora l. (3). structure of magnoflorine. | | 1954 | 14356874 |
| [repellent and antifeedant effect of secondary metabolites of non-host plants on plutella xylostella]. | based on the theory of co-evolution between plants and phytophagous insects, the repellent and antifeedant effect of secondary metabolites of non-host plants on diamondback moth(dbm) plutella xylostella was studied, aimed at finding out the oviposition repellents and antifeedants of insect pests. when the ethanol extracts(etho exts) of bauhinia variegata, eucalyptus tereticornis, euphorbia hirta, duranta repens, zanthoxylum bungeanum, magnolia grandiflora, and nicotiana tabacum were applied resp ... | 2004 | 15228000 |
| [study of magnolia grandiflora extracts in guinea pigs cardiac muscle]. | several extracts from diverse magnolia grandiflora varieties were pharmacological evaluated in the cardiac muscle. from march to july, flowers and leaves from magnolia grandiflora, native from the national institute of cardiology "ignacio chávez", from north, west, and orient zones from mexico city, and from puebla, colima and chiapas states were collected. they were separately processed and the extracts were obtained by maceration with ethanol-water (1:3 v/v) at 4 degrees c during two weeks. qu ... | 2004 | 15291039 |
| anti-inflammatory and anti-hyperalgesic effects of sesquiterpene lactones from magnolia and bear's foot. | sesquiterpene lactones possess a variety of biological activities, including anti-inflammatory activity. two plants native to the southeastern united states, magnolia grandiflora (l.) and smallanthus uvedalius (l.) [syn polymnia uvedalius (l.)], are novel sources of the sesquiterpene lactones parthenolide and enhydrin, respectively. in this study, the anti-inflammatory and anti-hyperalgesic effects of these isolated lactones from these two plant sources were evaluated in the rat carrageenan infl ... | 2004 | 15501305 |
| coumarins and sesquiterpene lactones from magnolia grandiflora leaves. | | 1994 | 17236065 |
| screening and isolation of a nematicidal sesquiterpene from magnolia grandiflora l. | the ethanolic extracts from 30 plant species were tested for their nematicidal activity against nematodes bursaphelenchus xylophilus (steiner & buhrer) nickle and panagrellus redivivus (l.) goodey. the leaf extract of magnolia grandiflora l. exhibited the strongest nematicidal activity against both nematodes, causing 73 and 100% mortality respectively within 48 h at 5 mg ml(-1). a new nematicidal sesquiterpene was obtained from the leaves of m. grandiflora. the compound was determined to be 4,5- ... | 2007 | 17304632 |
| constituents of magnolia grandiflora i: mono-o-methylhonokiol. | | 1982 | 17396785 |
| constituents of magnolia grandiflora, cyclocolorenone. | | 1982 | 17402129 |
| vulgarenol, a sesquiterpene isolated from magnolia grandiflora, induces nitric oxide synthases ii and iii overexpression in guinea pig hearts. | vulgarenol, a sesquiterpene isolated from magnolia grandiflora flower petals, decreased coronary vascular resistance in the langendorff isolated and perfused heart model, when compared to the control group [(15.2 x 10(7) +/- 1.0 x 10(7)) dyn s cm(-5) vs. (36.8 x 10(7) +/- 1.2 x 10(7)) dyn s cm(-5)]. our data suggest that this coronary vasodilator effect probably involved inducible and endothelial nitric oxide synthase overexpression (6.8 and 4.2 times over control, respectively), which correlate ... | 2007 | 18069247 |
| biochemical and genomic characterization of terpene synthases in magnolia grandiflora. | magnolia grandiflora (southern magnolia) is a primitive evergreen tree that has attracted attention because of its horticultural distinctiveness, the wealth of natural products associated with it, and its evolutionary position as a basal angiosperm. three cdnas corresponding to terpene synthase (tps) genes expressed in young leaves were isolated, and the corresponding enzymes were functionally characterized in vitro. recombinant mg25 converted farnesyl diphosphate (c(15)) predominantly to beta-c ... | 2008 | 18467455 |
| coronary vasodilator activity of vulgarenol, a sesquiterpene isolated from magnolia grandiflora, and its possible mechanism. | the aim of this study was to investigate the biodynamic effects of vulgarenol, a sesquiterpene isolated from magnolia grandiflora flower petals and its possible mechanism on the langendorff isolated and perfused heart model. vulgarenol (5 microm) caused a statistically significant decrease in coronary vascular resistance (15.21 +/- 6.00 dyn s cm(-5) vs 36.80 +/- 5.01 dyn s cm(-5), control group), increased nitric oxide release (223.01 +/- 8.76 pmol/ml vs 61.00 +/- 12.00 pmol/ml, control group) a ... | 2009 | 19107855 |
| neolignans from north american magnolia species with cyclooxygenase 2 inhibitory activity. | based upon reported ethnomedicinal use by native americans, extracts and pure isolates from leaves and seeds of magnolia grandiflora, m. virginiana, m. acuminata and m. macrophylla, all native to the southeastern united states, were investigated for their anti-inflammatory potential against cyclooxygenase 2 (cox-2). | 2009 | 19214385 |
| natural occurrence of entomogenous nematodes in tennessee nursery soils. | to isolate potential insect biocontrol agents, entomogenous nematodes were surveyed in tennessee plant nurseries in 1991. soil samples from 113 nursery sites were baited with greater wax moth (galleria mellonella) larvae, house cricket (acheta domesticus) adults, lesser mealworm (alphitobius diaperings) adults, and house fly (musca domestica) larvae. heterorhabditis bacteriophora and steinernema carpocapsae were each recovered from 17 soil samples. heterorhabditis bacteriophora was more common i ... | 1993 | 19279756 |
| giant flowers of southern magnolia are hydrated by the xylem. | flowering depends upon long-distance transport to supply water for reproductive mechanisms to function. previous physiological studies suggested that flowers operated uncoupled from stem xylem transport and received water primarily from the phloem. we demonstrate that the water balance of southern magnolia (magnolia grandiflora) flowers is regulated in a manner opposite from that of previously examined flowers. we show that flowers of southern magnolia rely upon relatively efficient xylem hydrau ... | 2009 | 19403730 |
| design and synthesis of ten biphenyl-neolignan derivatives and their in vitro inhibitory potency against cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated ltb4-formation. | a set of ten derivatives of methylhonokiol, an anti-inflammatory active biphenyl-type neolignan from magnolia grandiflora, has been evaluated for their in vitro cyclooxygenase-1/2 (cox-1/2) inhibitory activity using assays with purified prostaglandin h synthase (pghs)-1 and pghs-2 enzymes as well as for their 5-lipoxygenase (5-lox) mediated ltb(4) formation inhibitory activity using an assay with activated human polymorphonuclear leukocytes. the derivatization reactions included methylation, ace ... | 2009 | 19481465 |
| honokiol-mediated inhibition of pi3k/mtor pathway: a potential strategy to overcome immunoresistance in glioma, breast, and prostate carcinoma without impacting t cell function. | inhibition of the phosphoinositide 3-kinase (pi3k)/mammalian target of rapamycin (mtor) pathway is an appealing method for decreasing the immunoresistance and augmenting t cell-mediated immunotherapy. a major impediment to this strategy is the impact of conventional pi3k/mtor pathway inhibitors on t cell function. in particular, rapamycin, is a well-known immunosuppressant that can decrease the activity of the pi3k/mtor pathway in tumor cells, but also has a profound inhibitory effect on t cells ... | 2009 | 19483651 |
| cytotoxic and antiviral activities of aporphine alkaloids of magnolia grandiflora l. | bioassay guided fractionation of the methanol extract of magnolia grandiflora l. (magnoliaceae) leaves led to the isolation and characterisation of four aporphine alkaloids, magnoflorine, lanuginosine, liriodenine and anonaine. the cytotoxicities of the pure compounds magnoflorine and lanuginosine were determined in a cell viability assay with the tumour cell lines hela (cervix tumour cell line), hepg2 (hepatocellular carcinoma cell line) and u251 (brain tumour cell line). magnoflorine was more ... | 2010 | 19764006 |
| mapping urban forest tree species using ikonos imagery: preliminary results. | a stepwise masking system with high-resolution ikonos imagery was developed to identify and map urban forest tree species/groups in the city of tampa, florida, usa. the eight species/groups consist of sand live oak (quercus geminata), laurel oak (quercus laurifolia), live oak (quercus virginiana), magnolia (magnolia grandiflora), pine (species group), palm (species group), camphor (cinnamomum camphora), and red maple (acer rubrum). the system was implemented with soil-adjusted vegetation index ( ... | 2011 | 20140503 |
| screening of novel low-cost adsorbents from agricultural residues to remove ammonia nitrogen from aqueous solution. | most studies on ammonia adsorption from aqueous solution have been focused on mineral materials. however, a series of batch experiments were performed in this study to screen novel adsorbent materials from 80 agricultural residues, and to investigate the adsorption characteristics of six screened samples. the results showed that the ammonia adsorption efficiencies of 11 agricultural residues were comparable to those of minerals. the equilibrium data fitted well with both the langmuir and freundl ... | 2010 | 20189302 |
| vasoactive and antioxidant activities of plants used in mexican traditional medicine for the treatment of cardiovascular diseases. | this study demonstrated that the aqueous extracts of plants employed in mexican traditional medicine for the treatment of cardiovascular diseases are able to modify the tone of arterial smooth muscle. agastache mexicana (kunth) lint & epling (labiatae), chenopodium murale l. (chenopodiaceae), chirantodendron pentadactylon larreat (sterculiaceae), dracocephalum moldavica l. (labiatae), psittacanthus calyculatus g. don (loranthaceae), prunus serotina ssp. capuli (cav. ex spreng) mcvaugh (rosaceae) ... | 2010 | 20645769 |
| annual and seasonal variation in the phyllosphere bacterial community associated with leaves of the southern magnolia (magnolia grandiflora). | the phyllosphere contains a diverse bacterial community that can be intimately associated with the host plant; however, few studies have examined how the phyllosphere community changes over time. we sampled replicate leaves from a single magnolia (magnolia grandiflora) tree in the winter of three consecutive years (2007-2009) as well as during four seasons of 1 year (2008) and used molecular techniques to examine seasonal and year-to-year variation in bacterial community structure. multivariate ... | 2011 | 20809288 |
| apoptosis induced by magnolia grandiļ¬ora extract in chlorambucil-resistant b-chronic lymphocytic leukemia cells. | b-cell chronic lymphocytic leukemia (b-cll) still remains as an uncurable disease. even the newest antineoplastic agents have demonstrated limitations in their efficacy. for this reason, further research of new compounds must be done. new pharmacological properties can be obtained from a great diversity botanical species. among these products, magnolia grandiflora receives our attention since it mainly contains honokiol which had demonstrated effect against b-cll cells activating different cell ... | 2010 | 21358081 |
| winter biology of wetland mosquitoes at a focus of eastern equine encephalomyelitis virus transmission in alabama, usa. | at temperate latitudes, vectors and pathogens must possess biological mechanisms for coping with cold temperatures and surviving from one transmission season to the next. mosquitoes that overwinter in the adult stage have been proposed as winter maintenance hosts for certain arboviruses. in the cases of west nile virus (family flaviviridae, genus flavivirus) and st. louis encephalitis virus (family flaviviridae, genus flavivirus), discovery of infected overwintering females lends support to this ... | 2011 | 21936314 |
| [magnetic response of street tree leaves to particulate pollution in shanghai]. | to reveal the magnetic response to atmospheric particulate pollution in tree leaves along urban streets, twenty-four evergreen tree leaves were collected from green belt along jinshajiang road, shanghai, which were subjected to magnetic and heavy metals (zn, cu, pb) analyses. the result revealed that in all leaf samples chi, sirm varied in ranges of (4-59) x 10(-8) m3 x kg(-1) and (496-6 114) x 10(-6) am2 x kg(-1), respectively, s(-300mt) varied from 89% to 98% and chi(arm)/chi < 4, chi(arm)/sir ... | 2012 | 23379141 |