| a new method of allergen standardization. passive cutaneous anaphylaxis inhibition in a mouse-to-rat system in comparison with other methods. | various methods have been employed for standardization of potency of allergen extracts. we used passive cutaneous anaphylaxis (pca) inhibition in a mouse-to-rat system as a new means of standardization. several allergen extracts, including mite, short ragweed, house dust, aspergillus, candida, and japanese cedar, were examined. mouse ige antibodies were produced after two or three injections of antigen and alum. the potency measured by pca inhibition in the mouse-to-rat system was compared with ... | 1979 | 429715 |
| sugar production from agricultural woody wastes by saccharification with trichoderma viride cellulase. | the saccharification of agricultural woody wastes was studied using a commercial enzyme preparation, cellulase onozuka, derived from trichoderma viride or the solid culture extracts of the fungus. with the intention of producing sugar at low cost, a simple procedure of enzymatic saccharification of rice straw, bagasse, and sawdust was studied. delignifying methods of these wastes were investigated using dilute sodium hydroxide solution and dilute peracetic acid. rice straw and bagasse were effec ... | 1975 | 1238127 |
| measurement of serum ige antibodies against japanese cedar pollen (cryptomeria japonica) in japanese monkeys (macaca fuscata) with pollinosis. | ige antibodies against allergens of japanese cedar (cryptomeria japonica, cj) pollen in the serum of seven japanese monkeys (macaca fuscata) with pollinosis were measured by fluorometric indirect enzyme-linked immunosorbent assay (elisa). all of the monkeys were found to have specific ige to the crude pollen antigen. the specific ige levels were well correlated with those determined by the pharmacia cap system. ige antibodies were then assayed with two kinds of purified allergens (cry j i and cr ... | 1992 | 1297854 |
| [false positive reaction in measurement of allergen-specific ige--comparison of 3m ige fast-plus test using polystyrene well as adsorbent with phadezym rast]. | irrelevant ige binding to cellulose discs is known to give false positive results in phadezym rast (pharmacia) for the estimation of allergen-specific ige in serum. we investigated fast-plus test (3m diagnostic systems), an enzyme-linked sandwich type fluoro-allergo-sorbent test in which a particular allergen was coated to polystyrene well. phadezym rast and cap rast (pharmacia) using cellulose-derivative discs as adsorbent were used as reference methods. patients' sera which gave negative blank ... | 1992 | 1307629 |
| responses of isolated japanese monkey tracheal muscle to allergic mediators. | the responsiveness of isolated japanese monkey (macaca fuscata) tracheal muscle to antigen, carbachol, histamine, leukotriene c4 (ltc4), u-46619 and substance p (sp) was compared to that of isolated human trachea. weak but persistent contraction was observed after the addition of antigen to isolated japanese monkey tracheal muscle passively sensitized with monkey serum containing ige antibody against japanese cedar (cryptomeria japonica) antigen. unlike monkey tracheal muscle, a fair amount of c ... | 1992 | 1378043 |
| antigenic analyses of sugi basic protein by monoclonal antibodies: i. distribution and characterization of b-cell-tropic epitopes of cry j i molecules. | using 23 monoclonal antibodies raised against sugi basic protein (sbp, major allergen of japanese cedar pollen), composed of cry j i and cry j ii, analyses of b-cell-tropic epitopes of cry j i were performed. the following results were obtained. (1) as far as the mabs were used, no major cross-reactive determinants were detected between cry j i and cry j ii molecules. (2) 21 of the 23 mabs were specific for cry j i, and the anti-cry j ii mabs were classified into four groups by their fine specif ... | 1992 | 1379504 |
| skin tests of pollen grains of taxodiaceae and cupressaceae in children with bronchial asthma. | atmospheric cedar pollen in the southern region of okayama prefecture (situated in south-western japan) has been counted since 1988. pollen of different species of the taxodiaceae family (cryptomeria japonica, sequoia sempervirens and metasequoia glyptostroboides) and japanese juniper (juniperus rigida) in the cupressaceae family, which are propagated mainly in the southern region of okayama prefecture, were found among the atmospheric pollen. scratch tests using the pollen extract from taxodiac ... | 1992 | 1442021 |
| [evaluation of oriton ige, a new kit for measurement of allergen specific ige antibodies]. | to determine whether oriton ige kit, a new kit for the measurement of allergen-specific ige antibodies, is useful in screening allergen-specific antibody, we measured the titers of ige antibodies against 11 different allergens (house dust 2, dermatophagoides farinae, japanese cedar, ragweed pollen, egg white, milk, cat epithelium, dog epithelium, candida, alternaria and aspergillus) with the oriton ige kit, and the results were compared to those of intradermal tests and rast in 103 allergic pati ... | 1992 | 1444828 |
| [evaluation of the sensitized condition of patients with allergic diseases in okinawa using the mast allergy system]. | we determined, using the mast system, specific ige antibodies to allergens in the circulating blood of 127 patients with bronchial asthma, allergic rhinitis and atopic dermatitis in okinawa. the positive rates to inhalant allergens in all patients examined by the mast system were as follows: dermatophagoides farinae 65%, house dust 58%, cat epithelium 17% and japanese cedar 9%. in addition, the positive rates to food allergens found in all patients were as follows: wheat 16%, shrimp 14%, egg whi ... | 1992 | 1444829 |
| [elimination of japanese cedar (cryptomeria japonica) aeropollen by rainfall]. | the concentration of aeropollens of japanese cedar decreases on rainy days, due to the rainfall removing pollens from the atmosphere. an analysis was performed of the concentration of pollen grains in rain water samples from yokohama during the period february 10 to april 30, 1991. sampling of rain water was performed using an automatic rain water collector, and an analysis performed on each mm of rainfall, from 1 mm to 5 mm. in this collector, 1 mm of rainfall corresponds to 100 ml of accumulat ... | 1992 | 1467547 |
| [classification of allergens by positive percentage agreement and cluster analysis based on specific ige antibodies in asthmatic children]. | classification and characterization of allergens is important because allergic patients are sensitized by a variety of allergens. one hundred and sixty-one sera from asthmatic children were investigated for specific ige antibodies against 35 allergens including 20 inhalants and 15 foods by means of the mast method. we assessed the allergenic properties of the allergens based on positive percentage agreement and cluster analysis. there was a high positive percentage agreement of specific ige anti ... | 1992 | 1482294 |
| the effect of recombinant human interleukin-5 on eosinophil accumulation and degranulation in human nasal mucosa. | recombinant human interleukin-5 (rhil-5) was administered repeatedly onto the nasal mucosa of individuals with japanese cedar pollinosis outside the pollen season. the numbers of eosinophils and epithelial cells and the amount of eosinophil cationic protein (ecp), secretory iga (s-iga), and iga in the nasal lavage fluid increased significantly after the application of rhil-5. responsiveness to histamine was also enhanced after the application. when s-iga was administered onto the nasal mucosa af ... | 1992 | 1500623 |
| ipd-1151t: a prototype drug for ige antibody synthesis modulation. | ipd-1151t [(+/-)-[2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]-ethyl] dimethylsulfonium p-toluenesulfonate] inhibits not only antigen-induced histamine release from mast cells but also ige antibody formation. the present paper describes the inhibitory effect of ipd-1151t on the ige antibody formation. the ige antibody formation in balb/c mice which had been immunized with dinitrophenylated ascaris extract (dnp.as) plus alum was inhibited dose-dependently by ipd-1151t given p.o. the formation ... | 1991 | 1665310 |
| platelet-activating factor (paf) in allergic diseases: inhibitory effects of anti-allergic drugs, ketotifen and three kampo medicines on paf production. | platelet-activating factor (paf) is considered an important mediator in allergic and inflammatory reactions. to further investigate the role of paf in allergic diseases, we examined the in vitro and ex vivo effect of anti-allergic drugs on paf production by human neutrophils. ketotifen and three kampo medicines, which are widely used in the treatment of allergic diseases in japan, inhibited paf production by normal human neutrophils dose-dependently, whereas disodium chromoglycate (dscg) and tra ... | 1991 | 1726443 |
| existence of exine-free airborne allergen particles of japanese cedar (cryptomeria japonica) pollen. | we investigated whether exine-free pollen allergen particles exist together with the intact pollen grains of japanese cedar (cryptomeria japonica) in the air during the pollen season in yamagata city. first, we separated the allergen particles in an andersen multi-stage air-sampler according to their aerodynamic diameters. the amount of major allergen (cry j i) on each stage of the sampler was determined by a sensitive fluorometric sandwich elisa, and the pollen count of the same samples was don ... | 1991 | 1789400 |
| rast in diagnosis and therapy of allergic rhinitis. | skin tests, rast, nasal provocation tests, and other nasal allergy examinations were performed on 463 patients exhibiting symptoms of allergic rhinitis who were examined at the department of otolaryngology of osaka city university medical school, and comparisons were made between the rast scores and the results of the other examinations. a study was also made of the change in grade of the allergic rhinitis and the change of the rast score resulting from one year of immunotherapy. the rates of ag ... | 1991 | 1842868 |
| [analysis of the regulation of igg production to cryptomeria japonica pollen antigen]. | genetic control of the immune response to cryptomeria japonica pollen antigen (cpag) in humans was analyzed using 72 unrelated healthy adults. the 72 were classified into a low responder group and a high responder group by using purified cpag. significant associations were found between igg low responsiveness to purified cpag and possession of hla-dqw3. relative risks for the two groups were 4.80. peripheral blood lymphocytes from low responders revealed a specific igg response to cpag when the ... | 1991 | 1906704 |
| [relationships between the pollen productions in sugi (cryptomeria japonica d. don) forests and the patterns of atmospheric scattering pollens in toyama prefecture--the example of toyama prefecture in 1990]. | we investigated the geographical distribution of sugi (cryptomeria japonica d. don) forests and the male flower-setting conditions of them in toyama prefecture. the relationships between our findings and the atmospheric pollen scattering patterns were also studied. the results were as follows. 1. atmospheric pollen counts and their scattering patterns were fairly easily explained by the geographical distribution of 30-year old sugi forests, the male flower-setting conditions and the first day po ... | 1991 | 1958135 |
| comparison of a multi-allergen dipstick ige assay to skin-prick test and rast. | a multi-allergen dipstick enzyme immunoassay 'quidel allergy screen' (qas) has recently been developed commercially for measuring ige antibodies against nine allergens (house dust 1, house dust 2, dermatophagoides pteronyssinus, d. farinae, japanese cedar, ragweed, cat dander, sweet vernal grass, and egg white) at one time. to assess whether this assay is useful in screening allergen-specific ige antibody, we compared the titres of ige antibodies against the nine allergens measured by qas to tho ... | 1990 | 2192782 |
| [daily japanese cedar pollen forecast in sendai]. | the forecast of daily japanese cedar (cryptomeria japonica) pollen counts was performed in sendai in 1987, 1988 and 1989. the expected daily maximum temperature was used as a main determinative factor, and the term "pollen index", which is a ratio of a daily pollen count to the rest of the total seasonal pollen count, was devised and proved to be closely related to the daily maximum temperature. in 1987 and 1989, the total seasonal pollen count was very low, and daily pollen counts were in the l ... | 1990 | 2348275 |
| an ecological study on air pollution: changes in annual ring growth of the japanese cedar and prevalence of respiratory symptoms in schoolchildren in japanese rural districts. | the effect of air pollution caused by oil-fired electricity-generating stations on the annual ring growth of the japanese cedar (cryptomeria japonica, d. don) and prevalence of respiratory symptoms in schoolchildren were investigated. by retrospective analysis the annual ring growth has been demonstrated to show good agreement with the general trend in air pollution. in addition it was found to be related to the prevalence of respiratory symptoms. the reduction in annual ring growth and increase ... | 1990 | 2351128 |
| identification of the second major allergen of japanese cedar pollen. | we isolated and characterized the second major allergen (cry j ii) from japanese cedar pollen. we found that most patients with this pollinosis had ige antibody to this protein in addition to ige antibody to cry j i; however, some sera reacted only with cry j i or cry j ii. ige-elisa inhibition studies revealed that cry j i and cry j ii had no cross-allergenicity. cry j ii did not react with anti-cry j i monoclonal antibodies. in sds-page under a non-reducing condition, cry j ii showed a band at ... | 1990 | 2382797 |
| investigation of the genetic regulation in allergic rhinitis. | human leukocyte antigen (hla) population and family studies were performed to determine whether a specific hla type is associated with allergic rhinitis. we analyzed hereditary characteristics of allergic rhinitis using 27 nuclear families. according to the results of hla typing, we concluded that allergic rhinitis is certainly regulated by hla haplotype linked autosomal recessive inheritance. in addition, the frequency of hla dqw3 antigen, one of the hla class ii antigens, was higher in the pat ... | 1990 | 2390030 |
| [environmental and immunological survey of sensitization with japanese cedar (cryptomeria japonica) pollen in children. part 1. environmental factors influencing sensitization with japanese cedar (cryptomeria japonica) pollen among asthmatic children]. | | 1988 | 2467638 |
| functional differences of human basophils with different densities. | it has been reported that blood basophils comprise two populations of different densities. in this study, we compared the responses of two populations of basophils (band-1 and 2 basophils) to several secretagogues and anti-allergic agents. twelve patients with bronchial asthma, 3 patients with japanese cedar pollinosis and 6 healthy subjects were included in this study. band-2 basophils collected from the interface between percoll of density 1.078 and 1.068 g/ml released histamine better in resp ... | 1989 | 2470683 |
| [immunogenetic analysis of cryptomeria pollinosis. evidence for the hla-linked immune suppression gene to cryptomeria japonica pollen antigen]. | the ige response to cryptomeria japonica pollen antigen (cpag) in vivo was measured by radioimmunoassay, using plasma from 525 members of 98 families. 1) the 525 were classified into non plus low (non/low) responder group and high responder group. 2) segregation analysis revealed that the non/low responsiveness to cpag was formally a single dominant trait. 3) the frequency of this gene mediated for non/low responsiveness to cpag was calculated to be 0.44-0.60. 4) linkage analysis revealed that t ... | 1989 | 2524436 |
| [comparison of a new specific ige assay quidel allergy screen to skin prick test, intradermal test, and rast]. | quidel allergy screen (qas), an enzyme-linked immunosorbent assay, has been developed for measuring ige antibodies against 9 allergens (hd 1, hd 2, mite 1, mite 2, japanese cedar, ragweed, cat dander, sweet vernal grass, and egg white) at the same time. to determine whether this assay is useful in screening allergen-specific ige antibody, we compared the titers of ige antibodies against the 9 allergens measured by qas to the obtained in skin prick tests, in intradermal tests and by rast in 93 at ... | 1989 | 2589973 |
| [hourly variations in the dispersion of japanese cedar (cryptomeria japonica) pollens in the yamagata basin and the effect of cold and warm fronts on the pollen counts]. | airborne pollen counts of cryptomeria japonica (cj) were investigated at three points in the yamagata basin: 1. the central part of yamagata city (point a), 2. at the foot of a mountain with a cj grove (point b), 3. within the cj grove (point c). at the beginning of the cj pollen season, the airborne pollen counts at point b showed higher values than those at point a, whereas the relation of the count values was reversed later at the major pollen dispersion period. numerous airborne pollens were ... | 1989 | 2589976 |
| [dermatophagoides farinae and japanese cedar (sugi) pollen specific immunoglobuline e antibodies in asthmatic children measured by radioallergosorbent test and enzyme-linked immunosorbent assay]. | in recent years, pollinosis caused by japanese cedar pollen (cryptomeria japonica, sugi in japanese) has been increasing strikingly in japan. to investigate the prevalence and age-related sensitization of sugi pollen in children, the specific ige antibody was determined in 204 asthmatics (129 boys, 75 girls) by the enzyme-linked immunosorbent assay (elisa) and radioallergosorbent test (rast), and compared to dermatophagoides farinae (d.f.). there was a good correlation in the total serum ige lev ... | 1989 | 2589980 |
| [evaluation of allergen-specific ige antibodies by a newly developed mast allergy system]. | mast, which stand for multiple antigen simultaneous test, uses enzyme-linked anti-human ige and chemiluminogenic substate to determine ige. this system is characterized by simultaneous analysis of multiple allergen items, up to 35, together with total ige determination. we evaluated usefulness of this mast system using 191 serum samples obtained from patients with bronchial asthma, allergic rhinitis and/or atopic dermatitis. it was found that there were statistically significant correlations bet ... | 1989 | 2686587 |
| biological and immunological properties of sugi basic protein-pullulan conjugate. i. suppressive effect on ige antibody production and on ige-mediated reactions. | sugi basic protein (sbp), a major allergen of japanese cedar pollen, conjugated to pullulan acquires suppressive activities for ige, but not for igg antibody production, and for ige-mediated pk reactions in a sbp-specific manner. when either normal or ige anti-sbp antibody-producing mice were treated with the conjugate, ige anti-sbp antibody levels scarcely increased even after immunization with sbp + alum. this suppression was shown to be sbp specific and ige selective. the ability of sbp-pullu ... | 1989 | 2759711 |
| [a clinical study of two cases with immediate hypersensitivity to apple-pulp and an investigation of cross-allergenicity between apple-pulp allergen and some other pollen allergens]. | in japan there are no case reports of immediate hypersensitivity to apple-pulp. here, we report on two patients: a 23-year-old woman and a 14-year-old girl with 3-year and 7-year histories, respectively, of anaphylactic reactions to apple-pulp. in the first patient, eating raw apples immediately elicited itching and tingling of the lips and mouth with severe edema of the lips and tongue, irritation of the throat and slight colic in the upper abdomen. in the second, nausea and vomiting occurred a ... | 1989 | 2818215 |
| monoclonal antibody 4b4 blocks suppression of the immune response to cryptomeria japonica pollen antigen. | the monoclonal antibody 4b4 blocked the t8+ t cell-mediated suppression of ige response to cryptomeria japonica pollen antigen (cpag). the helper t cells for ige response to cpag expressed 4b4 specificity, whereas the suppressor t cells did not. the 4b4 molecule on pbl was a heterodimer and three additional bands were detected on activated cpag-specific t4+ t cells. they were not closely associated with hla molecules. it is thus conceivable that the 4b4 molecule is not only a marker of helper t ... | 1988 | 2968965 |
| a reverse-sandwich elisa for igg antibody to a pollen allergen. | we have developed a reverse-type sandwich elisa for measurement of igg (+iga) antibody to a major allergen of sugi (japanese cedar) pollens. in this assay, microplate wells were coated with the allergen proteins that had been dispersed in the presence of 0.5 mol/l nacl and 20 micrograms/ml of bovine serum albumin, followed by addition of test serum, and then the biotinylated allergen. beta-galactosidase-conjugated streptavidin was used for detection of the captured allergen, 4-methylumbelliferyl ... | 1988 | 3170988 |
| distribution of 90sr and 137cs in annual tree rings of japanese cedar, cryptomeria japonica d. don. | | 1988 | 3172041 |
| n-terminal amino acid sequence of a major allergen of japanese cedar pollen (cry j i). | a purified preparation of a major allergen of japanese cedar pollen, sugi basic protein (sbp, cry j i), was separated into 5 subfractions of 50-45 kda. all of the sbp subfractions were confirmed to be reactive to ige antibodies from patients with japanese cedar pollinosis, and also to mouse anti-sbp monoclonal antibodies. the sequences of 20 n-terminal amino acids of these 5 subfractions were found to be identical. peptide mapping analyses of the sbp subfractions showed similar patterns, with so ... | 1988 | 3181436 |
| [the annual variations in airborne cryptomeria japonica and cupressaceae pollen counts and meteorological conditions in fukuoka city--prediction of cryptomeria j. and cupressaceae pollen counts]. | | 1988 | 3240104 |
| anti-inflammatory constituents of topically applied crude drugs. ii. constituents and anti-inflammatory effect of cryptomeria japonica d. don. | | 1988 | 3245977 |
| [fine structure of the pollen of cryptomeria japonica]. | | 1986 | 3470071 |
| [experimental histological study on allergic conjunctivitis due to japanese cedar pollen]. | | 1986 | 3579614 |
| [atmospheric pollen counts of cryptomeria japonica and sugi pollinosis in the san-in area]. | | 1987 | 3606397 |
| cross-reactivity between the pollens of cupressus sempervirens (common cypress) and of cryptomeria japonica (japanese cedar). | a clinical and immunologic study was performed comparing a group of french patients allergic to the pollens of cypress (cupressus sempervirens, which belongs to the cupressaceae family) and a group of japanese patients allergic to the pollens of sugi (cryptomeria japonica, which belongs to the taxodiaceae family). by skin testing, rast, and rast inhibition, clear cross-reactivity was detected between the two pollens. no cross-reactivity was detected between the pollens of cupressus sempervirens ... | 1986 | 3729079 |
| [relationship between meteorological factors and pollen counts of cryptomeria japonica and cupressaceae in sakado city]. | | 1986 | 3767667 |
| ige antibody responses against japanese cedar pollen in the mouse. | ige antibody responses against japanese cedar pollen in the mouse were investigated to develop a mouse model of human allergy for combinations of factors including pollen administration routes, elicitation antigens and inbred mouse strains. daily short term inhalation of native pollen or intratracheal administration of pollen suspended in saline induced ige antibody responses in dba/2, bdf1 and balb/c mice, but failed to induce any detectable responses in c57bl/6 and c57bl/10 mice. intraperitone ... | 1986 | 3796321 |
| an epidemiological study on total and specific ige levels in japanese schoolchildren. | total serum ige, and specific serum ige against mites, ascaris and japanese cedar pollen were surveyed in 251 schoolchildren by a radioimmunoassay method. these children, aged from 10 to 13 years and living in a rural japanese town, were selected according to one-third random population sample. a high concentration of total serum ige (700 u/ml or more) was found in thirty-one children (12 x 3%). the sex ratio of these children, boys to girls, was 2 x 1:1. the cross-sectional and 6-year follow-up ... | 1982 | 6185250 |
| therapeutic effects of a new, anti-allergic ophthalmic preparation. | a 0.1% ketotifen ophthalmic preparation was evaluated in 11 cases of conjunctivitis due to japanese cedar pollinoisis (three cases also associated with vernal catarrh). the following results were obtained concerning the safety and the therapeutic efficacy of the preparation. (1) in the computation of the overall effects of the preparation, a marked therapeutic effect was noted in three out of 11 cases studied while one case remained unaffected. the overall effective rate was computed to be 91%. ... | 1982 | 7048635 |
| comparison of multiple-antigen simultaneous test and cap systems for diagnosis of nasal allergy. | the multiple-antigen simultaneous test (mast) is a simple system that uses no radioactive agents and allows simultaneous examination of multiple antigens. cap is a quick new, in vitro system that is more sensitive than the radio-allergosorbent test (rast). to evaluate their clinical efficacies, we examined the correlation between the mast and cap systems. serum samples were collected from 33 patients with nasal allergies, 13 males and 20 females, mean age 31.1 years. the mast and cap were used f ... | 1995 | 7478456 |
| induction of hepatic p450s in rat by essential wood and leaf oils. | 1. the effects of essential oils extracted from the wood and leaves of chamaecyparis obtusa, cryptomeria japonica and thujopsis dolabrata on p450s in the hepatic microsomes of the male rat have been investigated. 2. essential oils did not affect the content of total p450s measured photometrically. however, some metabolic activities and the levels of some forms of p450, including 2b1, were significantly increased, indicating their induction by essential oils. 3. the effects of components derived ... | 1995 | 7571719 |
| cry j 2, a major allergen of japanese cedar pollen, shows polymethylgalacturonase activity. | we examined cry j 2, a major allergen of japanese cedar (cryptomeria japonica) pollen, for polygalacturonase enzyme activity, since a nucleotide sequence of cdna of cry j 2 showed a significant homology with that of tomato polygalacturonase. polygalacturonase is well known to depolymerize preferentially polygalacturonic acid (pga) by hydrolysis. however, cry j 2 did not act on pga, but was found to depolymerize pectin and methylesterified pga in a dose-dependent manner. the substrate specificity ... | 1995 | 7573841 |
| [epidemiologic study of alnus sieboldiana matsumura (alder) pollinosis in ashiya city]. | alnus sieboldiana has been planted widely on denuded sites in the rokko mountains. its pollination season is in the latter half of that of japanese cedar. this epidemiologic study was carried out in ashiya in the 1991 spring hay fever season. the subjects were 532 female residents chosen at random, who had been living there more than ten years. there was an evident relation between the airbone alder pollen count and the prevalence of alder pollinosis. in the mountain town most severely inundated ... | 1995 | 7668998 |
| [investigation of cryptomeria japonica pollinosis in izu-oshima]. | we surveyed by questionnaire 4,673 residents of izu-oshima who were 15 or more years of age with regard to cryptomeria japonica pollinosis. the response rate was 22.3%. in the early spring, nasal symptoms were reported by 8.9% of the respondents, ocular symptoms by 5.7%, and dermal symptoms by 8.1%. on scratch tests of symptomatic subjects, 13.8% were positive for cryptomeria japonica antigen, and 33.3% had an ige rast score of 2 or more. the peak cryptomeria japonica pollen concentrations betwe ... | 1995 | 7668999 |
| substance p and vasoactive intestinal peptide in nasal secretions and plasma from patients with nasal allergy. | to clarify the role of substance p (sp) and vasoactive intestinal peptide (vip) in nasal allergy, we measured their concentrations in the nasal secretions and plasma of normal subjects and patients with nasal allergy to house dust and japanese cedar pollen by competitive enzyme-linked immunoassay. the mean levels of sp (224 pmol/l) and vip (41.6 pmol/l) in the nasal secretions of normal subjects were significantly higher than those in plasma (sp 3.04 pmol/l and vip 1.04 pmol/l; p < .01). the mea ... | 1993 | 7678375 |
| epitopes on cry j i and cry j ii for the human ige antibodies cross-reactive between cupressus sempervirens and cryptomeria japonica pollen. | forty sea from french patients allergic to cupressus sempervirens pollen were tested for cross-reactivities against cry j i, cry j ii (major allergens of cryptomeria japonica pollen) and other pollen allergens from botanically related plants. seventy-three per cent of the sera reacted with either cry j i or cry j ii, or with both of them. these ige cross-reactions were blocked effectively by mab 046 (anti-cry j i) or n26, t27 (anti-cry j ii), and weakly by mabs 052, 027 and 026 (anti-cry j i). f ... | 1993 | 7679186 |
| comparison of the mast chemiluminescent assay system with rast and skin tests in allergic children. | the mast chemiluminescent assay (cla) system uses enzyme-linked antihuman ige and a chemiluminogenic substance to determine specific ige antibodies. the mast cla system therefore not only makes unnecessary the precautions required for handling isotopic materials but has the advantage of long-term reagent stability. the mast cla system assay protocol consists of three steps: overnight incubation of serum, a 4-hour incubation with enzyme-labeled antibody, and a 30-minute chemiluminescent reaction, ... | 1993 | 7679259 |
| [sensitization and onset of japanese cedar pollinosis in children]. | recently, increases in cases of japanese cedar pollinosis have been found, especially in children. school children, junior high school students and high-school students in mibu-machi, tochigi prefecture were given questionnaires, rhinoscopic examinations were done and nasal secretions and blood samples were taken. the following results for the process of sensitization and the onset of japanese cedar pollinosis were found. according to the questionnaire, the percentage of positive japanese cedar ... | 1995 | 7702455 |
| specific ige to japanese cypress (chamaecyparis obtusa) in patients with nasal allergy. | japanese cedar (cryptomeria japonica) is the most important pollen causing pollinois during spring. during recent years some patients' nasal symptoms have been getting worse after the japanese cedar pollen season. japanese cypress (chamaecyparis obtusa) pollen is also observed in this period. the purpose of the study was to investigate the effect of japanese cypress pollen and cross-allergenicity between japanese cypress and japanese cedar in patients with allergic rhinitis. | 1995 | 7719888 |
| prevalence of ige antibody to crude and purified allergens of japanese cedar pollen among different troops of japanese monkeys (macaca fuscata). | we measured specific ige antibodies to the crude allergen as well as two purified allergens (cry j i and cry j ii) of japanese cedar (cryptomeria japonica--cj) pollen in the serum of 276 japanese monkeys in nine troops. of 45 monkeys with cj specific ige in eight of nine troops, 23 (51%) were found to have ige to both cry j i and cry j ii, 21 (47%) only to cry j i, and one (2.2%) only to cry j ii. the positive rate of specific ige antibody to each allergen varied among the troops. | 1994 | 7731029 |
| causative allergens of allergic rhinitis in japan with special reference to silkworm moth allergen. | to determine the importance of silkworm moth allergens, we tested 267 patients with allergic rhinitis with cap-rast, a new assay system for detecting specific ige in sera. we used the following allergen sources: house-dust mite, candida, alternaria, cat dander, orchard grass, ragweed, mugwort, japanese hops, japanese cedar, japanese cypress, cotton, silk, larval chironomid midge, adult chironomid midge, and silkworm moth. as expected, the highest positive rate of reaction, as determined by cap-r ... | 1995 | 7741185 |
| [prevalence of specific ige antibodies for dermatophagoides farinae and six inhalants in the general population]. | a seroepidemiologic study of house dust allergy and pollinosis was performed among a general population aged 17 to 69 in aichi prefecture, japan. the prevalence of blood containing ige antibodies to four perennial antigens and three seasonal antigens was examined among 198 persons whose serum total ige antibodies were above 40 iu/ml. the prevalence of blood containing ige antibodies was from 9 to 18 percent among perennial antigens and from 6 to 30 percent among seasonal antigens. these results ... | 1994 | 7919472 |
| allergen-specific human ige helper t cell lines derived from patients allergic to japanese cedar pollen. | to study the regulatory mechanism of allergen-dependent human ige synthesis, cry j i-specific and interleukin 4 (il-4)-producing cd4+ t cell lines (sn-4 and ss-12) were established from 2 patients allergic to japanese cedar pollen who highly expressed il-4 mrna in t cells in response to cry j i stimulation. upon stimulation of sn-4 and ss-12 cells with cry j i, il-4 production, which was observed at the protein and the mrna levels, was induced in an hla-dr-restricted manner, using autologous and ... | 1994 | 7920016 |
| antigenicity of the oligosaccharide moiety of the japanese cedar (cryptomeria japonica) pollen allergen, cry ji. | cry ji, a major allergenic glycoprotein of cryptomeria japonica (japanese cedar, sugi), is the most common pollen allergen in japan. carbohydrate analysis and lectin staining indicated that cry ji possesses the fucose/xylose-containing n-linked oligosaccharide which previously has been found in some plant glycoproteins. rabbit polyclonal anti-cry ji igg antibodies were found to be highly cross-reactive with two other plant glycoproteins which have the same type of oligosaccharides, and the cross ... | 1994 | 7920021 |
| ige-mediated hypersensitivity and contact sensitivity to multiple environmental allergens in atopic dermatitis. | atopic dermatitis (ad) is a chronic eczematous skin disease that develops in a patient with atopic diathesis, which is characterized by an increased liability to produce ige antibodies for environmental allergens mostly derived from other living organisms. experimentally, eczematous skin lesions cannot be induced by immediate ige-mediated reactions alone. they are produced by cell-mediated allergic contact reactions, and recently contact sensitivity to various environmental allergens has been de ... | 1994 | 7979440 |
| cdna cloning and expression of cry j ii the second major allergen of japanese cedar pollen. | we have isolated and sequenced a cdna clone coding for cry j ii, the second major allergen of japanese cedar (cryptomeria japonica) pollen. a 1.7-kilobase cdna clone contained an open reading frame coding for a 514-amino acid protein, including a putative signal peptide of 54 amino acid and three potential glycosylation sites. the deduced amino acid sequence of the cry j ii shows significant identities to those of the polygalacturonases associated with fruit-ripening in tomato (40%) and avocado ... | 1994 | 8002972 |
| cloning and sequencing of cdna coding for cry j i, a major allergen of japanese cedar pollen. | cdna clones coding for cry j i, a major allergen of the japanese cedar (cryptomeria japonica) pollen, have been isolated. two of the clones were sequenced and found to code for a putative 21-residue signal peptide and a 353-residue mature protein with a derived molecular weight of 38.5 kda. five possible n-linked glycosylation sites were found in the sequence. comparison of the nucleotide sequences of the two clones revealed sixteen nucleotide differences and these led to five amino acid exchang ... | 1994 | 8135802 |
| heterogeneous eosinophils of allergic rhinitis in chemotactic response. | chemotactic responses of eosinophils from patients with allergic rhinitis to 5 sto-2-derived eosinophil chemotactic factors (ecf), il-3, il-5 and gm-csf were examined. the patients were divided into two groups: patients with perennial allergic rhinitis sensitive to dermatophagoides farinae and those with seasonal allergic rhinitis sensitive to japanese cedar pollen. there was no essential difference between chemotactic response of eosinophils from the former to sto-2-derived ecf and that from he ... | 1994 | 8155995 |
| aggravation of experimental allergic conjunctivitis by environmental chemical and physical factors. | the effects of trichlorfon (dep, dipterex, anticholinesterase pesticide) and paraquat dichloride (gramoxon, inhibitor of superoxide dismutase) on passive anaphylactic reaction in guinea pig conjunctiva using japanese cedar pollen were quantitatively studied. for estimation of allergic conjunctivitis, evans blue after i.v. injection was extracted from conjunctiva and measured spectrophotometrically. allergic conjunctivitis was apparently aggravated by extremely low dosages of organophosphorus pes ... | 1993 | 8175053 |
| [analysis and regulation of interferon-gamma production by peripheral blood lymphocytes from patients with bronchial asthma]. | as with normal lymphocytes, small amounts of interferon-gamma (ifn-gamma) were spontaneously produced by lymphocytes from patients with bronchial asthma, and this bronchial asthma, and this production was markedly enhanced by concanavalin a (con a) stimulation. distinct from normal lymphocytes, however, ifn-gamma synthesis from patients' lymphocytes decreased in a dose dependent manner on stimulation with dermatophagoides farinae (df) antigen. ifn-gamma-producing cells are defined as being of th ... | 1994 | 8198458 |
| evaluation of allergen-specific ige antibodies by mast for the diagnosis of nasal allergy. | multiple-antigen simultaneous test (mast) is a new system for detecting allergen-specific ige antibodies. multiple antigens can be examined simultaneously in a short period of time by this method. the purpose of this study is to evaluate the usefulness of this method and to compare the results of mast with those of rast and intradermal skin test using 133 serum samples obtained from patients with nasal allergy. the positive rates of the main allergens detected by the mast system are 56% for japa ... | 1993 | 8321979 |
| [evaluation of immediate hypersensitivity and environmental factors by intracutaneous skin tests and specific ige antibodies in allergic children. part 1. the annual change of immediate hypersensitivity measured by intracutaneous skin tests and radioallergosorbent test]. | to evaluate the relation between immediate hypersensitivity and environmental factors, a total of 2,187 allergic children were given the intracutaneous skin tests (ic test) and specific ige antibodies (rast) at kudanzaka hospital over a period of 21 years (1967-1987). the incidence of positive ic test to house dust (hd) and japanese cedar pollen (sugi) increased, and that to molds increased transiently in the period 1965-1975. there was no sex difference in the incidence. asthmatic children with ... | 1993 | 8323455 |
| [immunological and physicochemical properties of cry j ii, the second major allergen of japanese cedar pollen (cryptomeria japonica)]. | cry j ii, the second major allergen of japanese cedar (sugi, cryptomeria japonica) pollen was examined for the allergenicity by intradermal test and rast. nineteen of the 25 allergic patients examined, showed positive reaction to the cry j ii. contents of cry j ii in the extracts of the pollen collected in various regions from 1977 to 1991 showed yearly variation ranging from 2.9 to 14 mg/100 g pollen, whereas the amount of cry j i in the extract was comparatively stable at about 35 mg/100 g pol ... | 1993 | 8347092 |
| [evaluation of the relationship between immediate hypersensitivity and environmental factors by intracutaneous skin tests and specific ige antibodies in allergic children. part 2. the age distribution of immediate hypersensitivity by intracutaneous skin test and radioallergosorbent test]. | to evaluate immediate hypersensitivity and environmental factors, 2,187 allergic children were given intradermal skin tests (id test) and specific ige antibodies (rast) at kudanzaka hospital for 21 years (1967-1987). the incidence of positive id test to house dust (hd) was 23% at 1 year, 50% at 2 years, 63% at 3 years and 84% at 8 years of age. the results of average positive test obtained at an earlier age in 1975 and 1985 than in 1965. children born recently begin to have positive test scores ... | 1993 | 8363435 |
| [repellent effect of wood odors on mites]. | since mites are known to react to odor, the repellent effect of wood odors on mites was measured with a simple indicative method of mite evasion behavior. this experiment confirmed that the odors of three types of trees including hinoki (chamaecyparis obtusa), pine (pinusdensiflora) and cedar (cryptomeria japonica), had repellent effects on tyrophagus putrescentiae, dermatophagoides farinae and d. pteronyssinus, mite specics which are comminly found in houses. the effects of lauan (shorea spp.) ... | 1993 | 8369535 |
| suppression of ige production by ipd-1151t (suplatast tosilate), a new dimethylsulfonium agent: (2). regulation of human ige response. | the ability of ipd-1151t to suppress the induction of human ige synthesis was investigated with an in vitro model of ige production mediated by an allergen-specific helper t cell line (sn-4) from a patient allergic to japanese cedar pollen. ipd-1151t induced a concentration-dependent suppression of purified allergen (cry j 1)-dependent ige synthesis in autologous b cell cultures mediated by sn-4, without significantly affecting the igg synthesis. in addition, the production of interleukin 4 (il- ... | 1993 | 8382323 |
| beta adrenergic receptor inhibitory factor in serum of patients with nasal allergy. | sera obtained from patients with perennial mite nasal allergy and japanese cedar pollinosis were examined to identify "beta receptor inhibitory factor". this was done by evaluating the inhibition of 3h-dihydroalprenolol binding to guinea pig cerebral membrane. beta receptor binding was inhibited by preincubation with sera from 8 of 44 (18.1%) perennial allergy patients, whereas sera from 2 of 41 (4.9%) controls showed this inhibition. sera from 6 of 41 pollenosis patients (14.6%) showed this inh ... | 1993 | 8383910 |
| a new method of counting airborne japanese cedar (cryptomeria japonica) pollen allergens by immunoblotting. | we have devised a new method of counting pollen allergen particles, modified from the fluorescent immunoblotting technique of schumacher et al. airborne japanese cedar pollen allergens collected on burkard's sampling tape were transferred onto a nitrocellulose membrane. the membrane was then treated with antiallergen mouse monoclonal antibody conjugated with alkaline phosphatase. pollen allergens were detected as purple spots on the nitrocellulose membrane after phosphate substrate staining was ... | 1993 | 8457039 |
| [antibody responses against japanese cedar pollen allergen (cry j i) in different strains of rats]. | we established an ige-capture elisa for rat ige antibody, and examined rat strain differences in the antibody responses against the major allergen of japanese cedar pollen (cry j i). first, ige-capture elisa and passive cutaneous anaphylaxis (pca) method were compared. ige-capture elisa was found to be, in sensitivity, about 10 times higher than, and, in specificity, equal to, pca. second, seven strains of rat were immunized three times at days 0, 14 and 28 by intraperitoneal injections of 1 or ... | 1993 | 8462638 |
| change in the northward movement of the pollen front of cryptomeria japonica in japan, during 1986-1991. | a map of pollen fronts of cryptomeria japonica was compiled from pollen counts taken at 28 airborne sampling sites in japan in 1986. thereafter, the number of sites was increased, reaching 80 in 1991. in this way an accurate and complete map of the c. japonica pollen fronts was compiled annually. we used the results obtained from mapping the pollen fronts to draw up a map of the average locations of the front, from which the beginning of the pollen season can be predicted. a close correlation wa ... | 1993 | 8489696 |
| hypersensitivity to japanese cedar (cryptomeria japonica) pollen in dogs. | four of 51 dogs with chronic dermatitis were made to react to crude japanese cedar (cryptomeria japonica, cj) pollen allergen by the intradermal skin test (idst). these four dogs had specific ige to cj as determined by prausnitz-küstner test. in the provocation test, nasal discharge increased 5 to 20 min after introduction of the crude cj pollen allergen into the nasal cavities, in two of three dogs. these results demonstrated that these dogs had hypersensitive to cj pollen, which might be a cau ... | 1995 | 8519898 |
| [relationships between atmospheric sugi (japanese cedar)-pollen counts and indices of climatic conditions]. | atmospheric pollen surveys have been conducted using durham's standard sampler for 12 years in toyama prefecture. the relationships between sugi (japanese cedar, cryptomeria japonica d. don) pollen and some indices of climatic conditions were analyzed. the results were as follows: 1. total pollen counts showed a tendency to increase for 12 years, although the variation of the count was relatively large. 2. significant correlations were found between pollen counts and some indices of the climatic ... | 1995 | 8520050 |
| sensitivity to two major allergens (cry j i and cry j ii) in patients with japanese cedar (cryptomeria japonica) pollinosis. | japanese cedar (cryptmeria japonica: cj) pollinosis is one of the most important allergic diseases in japan. recently, the second major allergen (cry j ii) was isolated from cj pollen. there have been no prevalence studies of sensitivity to cry j i and cry j ii among a large number of patients with pollinosis. | 1995 | 8564723 |
| single amino acid substitutions on a japanese cedar pollen allergen (cry j 1)-derived peptide induced alterations in human t cell responses and t cell receptor antagonism. | we generated t cell clones specific to a japanese cedar pollen allergen (cry j 1) and investigated effects of altered t cell receptor (tcr) ligand on changes of t cell responses. one of these cry j 1-specific t cell clones established from patients with japanese cedar pollinosis, st1.9, recognized an antigenic peptide cry j 1 p335-346 in the context of hla-dra+drb3*0301 molecules and secreted interleukin-4 dominantly, with a smaller amount of interferon-gamma. st1.9 represented one of the major ... | 1996 | 8568138 |
| allergic conjunctivitis caused by sugi (cryptomeria japonica d. don) pollen out of season. | allergic conjunctivitis caused by sugi pollen is considered to be strictly a "spring disease". however, a recent report indicated that sugi pollen is scattered not only in spring but in all seasons, especially in the autumn. we retrospectively determined the number of patients with allergic conjunctivitis caused by sugi pollen during each month for 3 consecutive years, and also investigated the growth of sugi male cones in november for four years. diagnosis of allergic conjunctivitis was based o ... | 1995 | 8703238 |
| [environmental factors influencing sensitization and onset of japanese cedar pollinosis among junior high school students]. | japanese cedar pollinosis has shown large increases especially in city areas, rather than in the rural, with increases being remarkable especially among people of young age. in order to elucidate factors for sensitization and onset of japanese cedar pollinosis, a questionnaire survey was conducted and serum ige antibody levels examined in junior high school students living in three different areas, i.e., city, seaside and mountainous areas in aichi prefecture. prevalence rate of japanese cedar p ... | 1996 | 8704271 |
| pollinosis etiologic relationship between excessive il-4 production and down-regulation of the inflammation-suppressive system. | previous findings suggest a bi-directional relationship between the immune and endocrine systems, which may expand to a major inflammation-regulatory mechanism, although its mechanism is largely unknown, especially in the human body. lymphokine and neuroendocrine peptide hormones have been identified as two major groups of immunologic mediators. the particularly pivotal molecules among them are interleukin (il-1), considered to be a mediator of inflammation, and acth, whose activation is induced ... | 1996 | 8740814 |
| [pollen dispersion of cryptomeria japonica in autumn]. | to clarify the significance of pollen dispersion of cryptomeria japonica in autumn, the distribution pattern of pollen dispersion using specimens collected from 1987 to 1995 by durhum collector was examined. after the dispersion period in the spring, the pollen count was suddenly decreased. the total pollen count from october to december showed no relation to the total pollen count for that of in spring of the same year; but it was closely correlated (r = 0.877) with the total pollen count durin ... | 1996 | 8752722 |
| [the pollen count of cryptomeria japonica and nasal symptom of cryptomeria japonica pollinosis patients in recent three years in mie prefecture]. | airborne scattering of cryptomeria japonica pollen depends on climate. total pollen count and scattering pattern varies from one year to another. we counted cryptomeria japonica pollen in february and march from 1993 to 1995 at several points in mie prefecture. one-third to two-thirds of all the patients who visited our clinic for the first time in the pollen period were occupied by allergic patients. the pollen count in 1995 amounted to 17943/cm2 at tsu and 99512/cm2 in the whole prefecture, wh ... | 1996 | 8776952 |
| japanese cedar pollinosis and hla-dp5. | japanese cedar pollinosis is a type i allergic disease caused by japanese cedar (cryptomeria japonica) pollen. we investigated the association between the disease and hla class ii alleles by hla-dna typing using a pcr-ssop method and found that the frequency of hla-dp5 (dpa1*02022 and dpb1*0501) was significantly increased in the patients. to investigate whether the hla-dp5 molecule is directly involved in the pathogenesis of the disease, japanese cedar pollen antigen (cpag)-specific t cell line ... | 1996 | 8813737 |
| [a comparative study of mast and cap rast with 90 patients with bronchial asthma]. | we measured serum ige antibodies by the mast and the cap rast in 90 patients refered to our asthma clinic and compared their results. furthermore the patients with cap positive/mast negative were investigated by bronchial provocation test with allergen, skin test and cap rast inhibition test. significant correlations were obtained between the results of the mast and those of the cap rast for house dust 2 (r = 0.617), for dermatophagoides farinae (r = 0.776) and for japanese cedar (r = 0.609), bu ... | 1995 | 8871294 |
| structures and contribution to the antigenicity of oligosaccharides of japanese cedar (cryptomeria japonica) pollen allergen cry j i: relationship between the structures and antigenic epitopes of plant n-linked complex-type glycans. | the oligosaccharide structures of cry j i, a major allergenic glycoprotein of cryptomeria japonica (japanese cedar, sugi), were analysed by 400 mhz 1h-nmr and two-dimensional sugar mapping analyses. the four major fractions comprised a series of biantennary complex type n-linked oligosaccharides that share a fucose/xylose-containing core and glucosamine branches including a novel structure with a nongalactosylated fucosylglucosamine branch. rabbit polyclonal anti-cry j i igg antibodies cross-rea ... | 1996 | 8872112 |
| immunodominance of seven regions of a major allergen, cry j 2, of japanese cedar pollen for t-cell immunity. | the immunodominant regions of the japanese cedar pollen allergen cry j 2 for t-cell immunity were determined with whole peripheral blood lymphocytes (pbl) derived from seven allergic patients and three nonallergic subjects. cry j 2-stimulated t-cell proliferation was inhibited by anti-hla-dr, but not by anti-hla-dq antibody, indicating that the responding t cells recognized the allergen peptides associated with hla-dr molecules. it was found that seven regions of cry j 2, i.e., regions correspon ... | 1996 | 8899114 |
| antigenic analysis of cryptomeria japonica and chamaecyparis obtusa using anti-cry j 1 monoclonal antibodies. | in japan, pollen of cryptomeria japonica and chamaecyparis obtusa are a yearly source of distress for many people suffering seasonally from allergic rhinitis. to study common epitopes shared by the two species, two monoclonal antibodies (moabs) were raised against cry j 1, which is the most predominant allergen in c. japonica. one of the moabs was found to be reactive even to the major allergen of c. obtusa, demonstrating that the moab (j1b01) can detect an epitope shared by both species j1b01 s ... | 1996 | 8908277 |
| dynamics of soluble adhesion molecule levels in patients with pollinosis. | to define the dynamics of systemic and local soluble adhesion molecule levels and to discuss the role of these molecules in the pathogenesis of allergic rhinitis. | 1996 | 8956759 |
| responses of monkeys with pollinosis to two major allergens of japanese cedar pollen. | we examined the responses of two japanese monkeys with pollinosis to two major allergens (cry j 1 and cry j 2) of japanese cedar pollen. the two monkeys (a and b) had specific ige antibodies to the allergens and showed a strong positive reaction to both of them in the intradermal test. in the histamine release test with peripheral blood mononuclear cells (pbmc), monkey a showed a typical pattern similar to that seen in human patients, while monkey b released a low level of histamine. the prolife ... | 1997 | 8980469 |
| [effect of fenitrothion on experimental allergic conjunctivitis]. | the effect of fenitrothion on experimental allergic conjunctivitis was studied using guinea pigs. guinea pigs were passively sensitized with anti-sera against ovalbumin (ova) or japanese cedar pollen. eight days after the sensitization, 6 x 10(-5) mg/kg to 6 mg/kg of fenitrothion were administered subcutaneously. two days after the injection, ova or japanese cedar pollen was given in the conjunctival sac and the allergic conjunctivitis was examined. ova or japanese cedar pollen induced the aller ... | 1996 | 9021657 |
| ige antibodies against midge and moth found in japanese asthmatic subjects and comparison of allergenicity between these insects. | the specific ige antibodies to moth (bombyx mori) and midge (chironomus yoshimatsui) were measured by the pharmacia cap system in 51 house-dust-mite-sensitive asthma patients. none of these patients had definite histories of exposure to these insects or apparent evidence of insect-induced asthma symptoms. the rast-inhibition assay was performed to investigate cross-allergenicity between these two insects. furthermore, ige immunoblotting was done to study the ige-binding components in moth and mi ... | 1997 | 9062632 |
| human t cell response to antigen peptides of japanese cedar pollen (cry j 1). | | 1997 | 9130539 |
| [effects of global climate change on japanese cedar pollen concentration in air--estimated results obtained from yamagata city and its surrounding area]. | the effects of global warming on japanese cedar pollen concentration in air were examined. there was a significant increase in total pollen count in years where small or average values of pollen dispersion were observed and where summertime temperatures were postulated to have risen from 2 to 5 degrees c. there were no remarkable differences in total pollen count in years where large values of pollen dispersion were observed. on the other hand, a drastic decrease in total pollen count was expect ... | 1996 | 9133338 |
| clinical effects of immunotherapy on japanese cedar pollinosis in the season of cedar and cypress pollination. | because of cross-allergenicity between cryptomeria japonica (japanese cedar) and chamaecyparis obtusa (japanese cypress) pollens, many japanese cedar pollinosis patients have symptoms during the cypress pollination season. therefore, the effect of immunotherapy (it) specific for japanese cedar pollinosis must be evaluated not only in the cedar season but also in the cypress season. eight out of 16 patients with cedar pollinosis who received it and the same number not receiving it (non-it) was st ... | 1997 | 9134139 |
| comparison of concentrations of cry j 1 and cry j 2 in diploid and triploid japanese cedar (cryptomeria japonica) pollen extracts. | japanese cedar (cryptomeria japonica) possibilities has been a serious allergic disease in japan. there are two kinds of japanese cedar trees; the popular one is diploid, the less popular is triploid. these trees are not very different morphologically. however, the relative allergenicity of their pollens is unknown, although both major allergens, cry j 1 and cry j 22, have been purified and cloned from the diploid line. triploid trees are sterile and the allergenicity of their pollen may differ. ... | 1997 | 9188931 |
| epitope specificity of ige antibodies to a major allergen (cry j 1) of japanese cedar pollen in sera of humans and monkeys with pollinosis. | japanese cedar (cryptomeria japonica) pollinosis has been reported to occur naturally in japanese monkeys (macaca fuscata) as well as humans. using monoclonal antibodies (mab) specific to cry j 1, a major allergen in japanese cedar pollen, we identified five independent epitopes (ep-1 to ep-5) on the molecule. the epitopes recognized by ige antibodies in the sera of humans and monkeys with the pollinosis were analysed by an ige enzyme-linked immunosorbent assay inhibition method with these mab. ... | 1997 | 9227312 |