| phylogeny of helicobacter felis sp. nov., helicobacter mustelae, and related bacteria. | strain cs1t (t = type strain) is a gram-negative, microaerophilic, urease-positive, spiral-shaped bacterium that was isolated from the gastric mucosa of a cat. additional strains which possessed biochemical and ultrastructural characteristics similar to those of strain cs1t were isolated from the gastric mucosa of cats and dogs. the guanine-plus-cytosine content of the dna of strain cs1t was 42.5 mol%. the 16s rrna sequences of strain cs1t, strain ds3 (a spiral-shaped isolate from a dog), and he ... | 1991 | 1704791 |
| revision of campylobacter, helicobacter, and wolinella taxonomy: emendation of generic descriptions and proposal of arcobacter gen. nov. | hybridization experiments were carried out between dnas from more than 70 strains of campylobacter spp. and related taxa and either 3h-labeled 23s rrnas from reference strains belonging to campylobacter fetus, campylobacter concisus, campylobacter sputorum, campylobacter coli, and campylobacter nitrofigilis, an unnamed campylobacter sp. strain, and a wolinella succinogenes strain or 3h- or 14c-labeled 23s rrnas from 13 gram-negative reference strains. an immunotyping analysis of 130 antigens ver ... | 1991 | 1704793 |
| helicobacter muridarum sp. nov., a microaerophilic helical bacterium with a novel ultrastructure isolated from the intestinal mucosa of rodents. | helical organisms with novel ultrastructural characteristics were isolated from the intestinal mucosa of rats and mice. these bacteria were characterized by the presence of 9 to 11 periplasmic fibers which appeared as concentric helical ridges on the surface of each cell. the cells were motile with a rapid corkscrewlike motion and had bipolar tufts of 10 to 14 sheathed flagella. the bacteria were microaerophilic, nutritionally fastidious, and physiologically similar to helicobacter species and w ... | 1992 | 1736969 |
| isolation and characterization of "flexispira rappini" from laboratory mice. | a bacterium with an unusual ultrastructure and possessing a fusiform protoplasmic cylinder, spiral periplasmic fibers, and bipolar tufts of sheathed flagella was identified in the intestinal mucosae of laboratory mice. the organism was cultured under microaerophilic conditions and was found to rapidly hydrolyze urea. on the basis of 16s rrna gene sequence analysis, the organism was shown to be "flexispira rappini." "f. rappini" is closely related to members of the genus helicobacter and has been ... | 1993 | 7504685 |
| arcobacter-specific and arcobacter butzleri-specific 16s rrna-based dna probes. | the genus arcobacter encompasses gram-negative, aerotolerant, spiral-shaped bacteria formerly designated campylobacter cryaerophila. two genus-specific 16s rrna-based oligonucleotide dna probes (23-mer and 27-mer) were developed. the probes hybridized with strains of arcobacter butzleri (n = 58), arcobacter cryaerophilus (n = 19), and arcobacter skirrowii (n = 17). the probes did not cross-react with any of the reference strains of campylobacter, helicobacter, including "flexispira rappini," or ... | 1995 | 7545177 |
| flexispira rappini suspected in ovine abortion. | | 1994 | 8073597 |
| helicobacter canis sp. nov., a new species from dogs: an integrated study of phenotype and genotype. | a group of campylobacter-like organisms (clos) were isolated from the faeces of diarrhoeic or healthy dogs, constituting 4% of all clos from this source. since they formed a unique dna homology group within the genus helicobacter, and exhibited distinctive phenotypic properties, they were collectively termed the hc group. a polyphasic taxonomic analysis was made of this group. the phenotype of four dog isolates and a single human isolate was unique and could be distinguished bacteriologically fr ... | 1993 | 8254320 |
| helicobacter acinonyx sp. nov., isolated from cheetahs with gastritis. | four strains of a novel helicobacter species were isolated from the stomachs of cheetahs (acinonyx jubilatus) with gastritis. these isolates were phenotypically similar to helicobacter pylori. the isolates were gram-negative, spiral bacteria which grew under microaerophilic conditions at 37 degrees c, but not at 25 or 42 degrees c, and produced urease, catalase, oxidase, alkaline phosphatase, and gamma-glutamyl transpeptidase. the isolates did not ferment glucose, mannitol, inositol, sorbitol, r ... | 1993 | 8379970 |
| lipid profile of helicobacter spp.: presence of cholesteryl glucoside as a characteristic feature. | the lipid and fatty acid profiles of eight helicobacter spp. (h. nemestrinae, h. acinonyx, h. canis, helicobacter sp. strain clo-3, "h. rappini" [flexispira rappini], h. pametensis, helicobacter sp. strain bird-b, and helicobacter sp. strain bird-c) and the fatty acid profiles of five additional species (h. pylori, h. felis, h. muridarum, h. mustelae, and h. fennelliae) were analyzed and compared. a heterologous fatty acid profile was observed among the helicobacter spp., and on that basis the s ... | 1996 | 8606185 |
| identification of murine helicobacters by pcr and restriction enzyme analyses. | three murine helicobacter species have recently been identified: helicobacter hepaticus, helicobacter muridarum, and helicobacter bilis. infections with h. hepaticus and h. bilis have been associated with hepatitis and hepatic neoplasia. in this study, oligonucleotide primers were designed from regions of the 16s rrna gene that are conserved among members of the helicobacter genus. the assay amplified the expected 374-bp product from all three rodent helicobacter species and was able to detect a ... | 1996 | 8815113 |
| prevalence and varieties of helicobacter species in dogs from random sources and pet dogs: animal and public health implications. | gastric bacteria of a variety of ultrastructural morphologies have been identified in or isolated from domestic carnivores, but their prevalence in different populations of animals and their clinical significance are still unknown. the purposes of this study were (i) to evaluate the prevalence and morphologic types of gastric bacterial in three different populations of dogs; (ii) to determine which of the organisms were culturable, and if the cultured organisms were morphologically similar to th ... | 1996 | 8940465 |
| morphological diversity of cultured canine gastric helicobacter spp. | the cell morphology, the number of flagella, the occurrence of periplasmic fibrils and ultrastructural structures of five groups of cultured canine gastric helicobacter spp. were compared. the study included four strains of helicobacter felis, four strains of helicobacter bizzozeronii, one strain of 'flexispira', six strains of an unnamed spiral organism 2 and one strain of an unnamed spiral organism 3 which were isolated from gastric biopsies. cultures were studied with negative staining, trans ... | 1997 | 9481513 |
| hepatic helicobacter species identified in bile and gallbladder tissue from chileans with chronic cholecystitis. | cancer of the gallbladder is the number one cause of cancer mortality in chilean women. incidence rates for this tumor vary widely on a worldwide basis, being approximately 30 times higher in high-risk than in low-risk populations, suggesting that environmental factors such as infectious microorganisms, carcinogens, and nutrition play a role in its pathogenesis. because several helicobacter sp. colonize the livers of animals and induce hepatitis, the aim of this study was to determine whether he ... | 1998 | 9516396 |
| "flexispira rappini" bacteremia in a child with pneumonia. | we describe a case of "flexispira rappini" bacteremia from a 9-year-old girl who presented with a 5-day history of fever, productive cough, and malaise. a chest x-ray result was compatible with right middle lobe pneumonia. blood culture grew a gram-negative spiral fusiform bacterium 2 days after the inoculation. biochemical tests showed the organism to be catalase negative, oxidase positive, sodium hippurate hydrolysis negative, and urea hydrolysis negative. 16s rrna gene sequencing identified t ... | 1998 | 9620399 |
| isolation and identification of helicobacter spp. from canine and feline gastric mucosa. | it is known that virtually all healthy adult dogs and cats harbor spiral helicobacters in their gastric mucosa. three species, helicobacter felis, helicobacter bizzozeronii, and helicobacter salomonis have been isolated in vitro from the gastric mucosa of these animals. the aims of this study were to evaluate the efficacy of an isolation method for canine and feline gastric helicobacters that has been developed at the university of helsinki; to estimate the prevalence and distribution of these t ... | 1998 | 9758832 |
| helicobacter colonization of the biliary tree: commensal, pathogen, or spurious finding? | the authors hypothesized that helicobacter species may be present in the bile and gallbladder wall of patients with chronic cholecystitis who live in a region with a high prevalence of gallbladder cancer. they attempted to identify such species by obtaining both bile and resected gallbladder tissue from 46 patients who underwent cholecystectomy. tissue specimens were stained with hematoxylin and eosin as well as other stains used specifically for the identification of helicobacter species, and c ... | 1998 | 9772078 |
| pathology, diagnosis and epidemiology of the rodent helicobacter infection. | since the first isolation of helicobacter pylori from humans in 1983, 18 helicobacter species have been identified during the last decade in domestic and laboratory animals. several helicobacter species have been isolated from the gastrointestinal tracts of various mammalian species and birds. helicobacter hepaticus, h. muridarum, h. bilis, h. rodentium and flexispira rappini have been isolated from mice. among these species, only h. hepaticos has been clearly recognized as a pathogen. indeed, i ... | 1999 | 10099028 |
| recurrent "flexispira rappini" bacteremia in an adult patient undergoing hemodialysis: case report. | a blood culture from a 65-year-old febrile man undergoing hemodialysis revealed, 5 days after inoculation, an unusual gram-negative fusiform rod with darting motility. during another episode of fever 21 days later, this campylobacter-like organism was again recovered from three blood cultures and subcultured under an h2-enriched microaerobic atmosphere. the organism was catalase negative and oxidase positive and hydrolyzed urea rapidly. sodium dodecyl sulfate-polyacrylamide gel electrophoresis a ... | 1999 | 10203478 |
| recurrent bacteremia caused by a "flexispira"-like organism in a patient with x-linked (bruton's) agammaglobulinemia. | helicobacter spp., except for helicobacter cinaedi, have only rarely been reported in cases of septicemia. a patient with x-linked (bruton's) agammaglobulinemia was found to have persistent sepsis with a helicobacter-like organism despite multiple courses of antibiotics. his periods of sepsis were associated with leg swelling thought to be consistent with cellulitis. the organism was fastidious and required a microaerophilic environment containing h(2) for growth. optimal growth was observed at ... | 1999 | 10405381 |
| occurrence and characterization of gastric helicobacter spp. in naturally infected dogs. | helicobacter-like organisms are frequently observed in the stomach of dogs but the relationship between these microorganisms and gastric pathology has not been clearly established. different species of helicobacters are known to be present in the canine stomach but their specific prevalence in naturally infected dogs is unknown. the aims of this study were to isolate and characterize helicobacters in canine gastric biopsies, to compare the commonly used tests for the identification of helicobact ... | 1999 | 10596807 |
| identification of a unique helicobacter species by 16s rrna gene analysis in an abdominal abscess from a patient with x-linked hypogammaglobulinemia. | a unique helicobacter species, mz640285, was isolated from a patient with x-linked hypogammaglobulinemia suffering from recurrent abdominal abscesses and was identified by 16s rrna gene sequence analysis. in the phylogenetic tree, the isolate fell into a cluster which included flexispira rappini, helicobacter bilis, and helicobacter sp. strain mainz. helicobacters are being increasingly recognized as pathogens in immunocompromised hosts. these fastidious bacteria are not easily cultured in the r ... | 2000 | 10878075 |
| current status of helicobacter contamination of laboratory mice, rats, gerbils, and house musk shrews in japan. | the current status of helicobacter contamination of laboratory mice, rats, gerbils, and house musk shrews from 47, 10, 4, and 3 colonies, respectively, in japan was studied. helicobacter was detected by reverse transcription (rt)-nested polymerase chain reaction (pcr) with helicobacter genus-specific primers by using feces obtained from the animals. h. hepaticus, h. muridarum, h. bilis, h. rodentium, "flexispira rappini", and "h. suncus" were identified with species-specific primers. other speci ... | 2000 | 10915200 |
| bacteremia and skin/bone infections in two patients with x-linked agammaglobulinemia caused by an unusual organism related to flexispira/helicobacter species. | two patients with bruton's x-linked agammaglobulinemia are described with bacteremia and skin/bone infection due to an organism which by 16s rrna gene sequence analysis was most closely related to "flexispira" rappini (and thus designated a flexispira-like organism, flo) and more distantly related to the helicobacter species. the organism required microaerobic conditions and, supplemental h(2) gas for growth and was reliably stained with acridine orange. in common with helicobacter cinaedi infec ... | 2000 | 11027452 |
| 'flexispira rappini' strains represent at least 10 helicobacter taxa. | 'flexispira rappini' is a provisional name given to gram-negative, microaerophilic, motile, spindle-shaped micro-organisms with spiral periplasmic fibres and bipolar tufts of sheathed flagella. several investigators, including kirkbride, romero, and archer isolated strains possessing this morphology. previously, the phylogenetic position of three 'flexispira rappini' strains was determined by 165 rrna sequencing, which indicated that flexispira were members of the genus helicobacter. as more org ... | 2000 | 11034487 |
| characterization of culture-derived spiral bacteria by 16s ribosomal rna gene sequence analysis. | broad range amplification and sequence analysis of the 16s ribosomal rna gene was used to identify three spiral-form organisms. the agents were identified as campylobacter fetus, "flexispira rappini", and borrelia burgdorferi, respectively, using either proprietary or public sequence databases. in each case, the rdna sequence showed 99-100% homology with known sequence data. sequence-based analysis for each isolate required only 2-3 days, whereas traditional means of identification took 8-12 day ... | 2001 | 11173192 |
| helicobacters of possible zoonotic origin: a review. | since the isolation of helicobacter pylori, many new helicobacter species have been identified from the gastrointestinal tract in humans and animals. in humans, a spiral organism different from h. pylori and provisionally named "helicobacter heilmannii", has been associated with gastritis, gastric ulceration and to a lesser degree, gastric cancer. in addition helicobacter cinaedi, helicobacter fennelliae, helicobacter pullorum and "flexispira rappini" have been isolated from cases of enteric dis ... | 2000 | 11233522 |
| recommendations of the subcommittee on the taxonomy of campylobacter and related bacteria. | the icsb subcommittee on the taxonomy of campylobacter and related bacteria has discussed several contemporaneous issues and makes the following recommendations. (i) the reported synonymy between campylobacter coli and campylobacter hyoilei was based on valid taxonomic arguments. the subcommittee therefore discourages the use of the name c. hyoilei. (ii) the revised infrasubspecific nomenclature of campylobacter sputorum is endorsed. c sputorum is subdivided into c. sputorum biovar sputorum (cha ... | 2001 | 11321120 |
| helicobacter sp. flexispira bacteremia in an immunocompetent young adult. | a young immunocompetent patient was admitted for a febrile illness with malaise, arthralgias, painful leg swelling, and polyserositis. shortly prior to becoming ill, the patient had traveled to the northern african desert. the symptoms disappeared during treatment with antibiotics (doxycycline and ceftriaxone) but recurred twice after stopping therapy. a motile gram-negative fusiform rod was isolated from a blood culture taken on the first admission. analysis of the 16s rrna gene of the blood cu ... | 2001 | 11325980 |
| coinfection of enteric helicobacter spp. and campylobacter spp. in cats. | during a 6-year period, 64 of 227 commercially reared cats had microaerobic bacteria isolated from their feces. all the isolates were initially identified as campylobacter-like organisms based on biochemical and phenotypic characteristics. dna extractions from 51 of these isolates were subjected to pcr using primers specific for helicobacter spp. and campylobacter spp. of the isolates, 92% (47 of 51 isolates) were positive for campylobacter spp., 41% (21 of 51 isolates) were positive for helicob ... | 2001 | 11376052 |
| helicobacter winghamensis sp. nov., a novel helicobacter sp. isolated from patients with gastroenteritis. | from 1997 to 1999 seven isolates of campylobacter-like organisms from five patients that were exhibiting symptoms of gastroenteritis, including fever, stomach malaise, and diarrhea, were investigated. the organisms were isolated from stool samples and found to exhibit a diverse colony morphology; hence multiple isolates were submitted from one of the patients. all isolates were found to be identical. the organisms were catalase, urease, alkaline phosphatase, and nitrate negative but oxidase and ... | 2001 | 11427547 |
| fatal gastrointestinal infection with 'flexispira rappini'-like organisms in a cat. | a 4-month-old male british blue cat with catarrhal to haemorrhagic enteritis showed massive colonization of the stomach, small intestine and caecum with spiral-shaped bacilli. in the stomach, organisms were located in foveolae and gland lumina and within unaltered and degenerate epithelial cells. inflammatory infiltration was moderate and t cell dominated. in the intestine, bacilli were found in the gut lumen, berween villi, in crypt lumina and within epithelial cells. degeneration of crypt epit ... | 2001 | 11471846 |
| identification of novel helicobacter species in pig stomachs by pcr and partial sequencing. | evidence of infection with helicobacter species in pig stomach was investigated by the use of a pcr with helicobacter genus-specific primers. forty pig stomachs, each of four different ulcer lesion grades, 0, 1, 2, and 3 in the pars esophagea area, were collected from a slaughterhouse in minnesota. of 160 stomach samples examined, 102 (63.8%) were positive by the pcr assay. the 40 samples each of lesion grades 0, 1, 2, and 3 showed 22.5, 52.5, 85.0, and 95.0% pcr-positive results, respectively. ... | 2001 | 11526168 |
| recurrent bacteremia and multifocal lower limb cellulitis due to helicobacter-like organisms in a patient with x-linked hypogammaglobulinemia. | we describe a 27-year-old man with x-linked (bruton's) hypogammaglobulinemia who presented during a 10-month period with recurrent fevers and multifocal lower-limb cellulitis associated with bacteremia due to helicobacter-like organisms ("flexispira rappini" and helicobacter canis). susceptible individuals may acquire infection of this type as a result of exposure to young dogs. | 2001 | 11595979 |
| isolation and characterization of campylobacter, helicobacter, and anaerobiospirillum strains from a puppy with bloody diarrhea. | we carried out a microscopic examination of stools from a 2-month-old female puppy with bloody diarrhea, and this revealed large numbers of different spiral-shaped bacteria. to isolate these organisms, a rectal swab specimen was inoculated onto plates of skirrow's agar and incubated at 37 degrees c for 6 days in a microaerobic atmosphere. finally, a total of six different spiral-shaped bacteria (strains g1104, 94105, fr106, b0101, 3j102, and j2103) were isolated. based on their morphology, bioch ... | 2002 | 12069772 |
| cytolethal distending toxin b gene (cdtb) homologues in taxa 2, 3 and 8 and in six canine isolates of helicobacter sp. flexispira. | the presence of the cytolethal distending toxin b gene (cdtb) was examined in eight helicobacter sp. flexispira reference strains, helicobacter trogontum atcc 700114(t) and 12 finnish porcine h. trogontum strains and canine flexispira isolates. part of the cdtb gene was amplified by pcr with degenerate primers vat2 and dhf1, cloned and sequenced. the presence/absence of the cdtb gene as determined by pcr was confirmed by southern hybridization and toxin production by hela cell-line experiments. ... | 2003 | 12543914 |
| the rapid detection of low molecular mass proteins differentially expressed under biological stress for four helicobacter spp. using proteinchip technology. | helicobacter pylori is one of the most prevalent human pathogens in the world and is the aetiological agent of gastritis, peptic ulcer disease and gastric malignancies. in addition h. pylori and other novel members of the genus are capable of successfully colonising the bile-rich niche of the upper intestine and are associated with a diverse range of intestinal pathologies. surface-enhanced laser desorption/ionisation-time of flight mass spectrometry was used to analyse surface extracts from h. ... | 2003 | 12627380 |
| helicobacter sp. flexispira 16s rdna taxa 1, 4 and 5 and finnish porcine helicobacter isolates are members of the species helicobacter trogontum (taxon 6). | the term 'flexispira' refers to micro-organisms with a particular morphology: fusiform-shaped with helical periplasmic fibrils and bipolar tufts of sheathed flagella. two flexispira taxa have been formally named, helicobacter bilis and helicobacter trogontum, a third named species is helicobacter aurati and eight additional 16s rrna sequence-based flexispira taxa have been described by dewhirst et al. (int j syst evol microbiol 50, 1781-1787, 2000) and given the provisional designation helicobac ... | 2003 | 12710608 |
| potential for proteomic profiling of helicobacter pylori and other helicobacter spp. using a proteinchip array. | the helicobacter genus is associated with a wide spectrum of pathologies in the gastrointestinal tract. however, in contrast to helicobacter pylori, few data are available regarding proteomic characteristics of enterohepatic helicobacters. proteomic analysis of this genus has predominantly utilised two-dimensional gel electrophoresis methodology. in the present study we applied an innovative technique using proteinchip arrays coupled with surface-enhanced laser desorption/ionisation time of flig ... | 2003 | 12738385 |
| isolation and characterization of novel helicobacter spp. from the gastric mucosa of harp seals phoca groenlandica. | since the recent discovery of helicobacter cetorum in cetaceans and its role in the development of gastritis, speculation has existed as to whether pinnipeds have helicobacter spp. associated gastritis and peptic ulcer disease. the gastric mucosa of 4 stranded harp seals phoca groenlandica from the massachusetts coastline were assessed for helicobacter spp. by culture and pcr. we cultured 2 novel helicobacter spp. from the pyloric antrum of 1 of the 4 harp seals studied, and identified these by ... | 2003 | 14735915 |
| phylogenetic analysis of gastric and enterohepatic helicobacter species based on partial hsp60 gene sequences. | analysis of 16s rrna gene sequences has been the method generally used to study the evolution and phylogeny of bacteria. phylogenetic analysis of the 16s rrna gene has shown the position of the genus helicobacter in the epsilon-subclass of the proteobacteria. because 16s rrna-based phylogeny does not always correspond to the results of polyphasic taxonomy, and the related species cannot always be separated, new phylogenetic markers for helicobacter species are needed. in this study, conserved pa ... | 2004 | 15143020 |
| comparative chemical and biological characterization of the lipopolysaccharides of gastric and enterohepatic helicobacters. | the lipopolysaccharide of helicobacter pylori plays an important role in colonization and pathogenicity. the present study sought to compare structural and biological features of lipopolysaccharides from gastric and enterohepatic helicobacter spp. not previously characterized. | 2004 | 15270745 |
| high prevalence of helicobacter species detected in laboratory mouse strains by multiplex pcr-denaturing gradient gel electrophoresis and pyrosequencing. | rodent models have been developed to study the pathogenesis of diseases caused by helicobacter pylori, as well as by other gastric and intestinal helicobacter spp., but some murine enteric helicobacter spp. cause hepatobiliary and intestinal tract diseases in specific inbred strains of laboratory mice. to identify these murine helicobacter spp., we developed an assay based on pcr-denaturing gradient gel electrophoresis and pyrosequencing. nine strains of mice, maintained in four conventional lab ... | 2004 | 15297530 |
| extension of the species helicobacter bilis to include the reference strains of helicobacter sp. flexispira taxa 2, 3 and 8 and finnish canine and feline flexispira strains. | the evolution and taxonomy of enterohepatic helicobacter species with flexispira morphology were studied by a polyphasic approach including phenotypic characterization, analysis of 16s rrna and ureb gene sequences and dot-blot dna-dna hybridization of whole genomic dna. in addition, available phylogenetic data on the hsp60 gene were used in the analysis. the study included 14 finnish canine and feline flexispira strains, the reference strains of helicobacter sp. flexispira taxa 2, 3 and 8 and he ... | 2005 | 15774681 |
| [flexispira rappini bacteremia and common variable immuodeficiency]. | | 2005 | 15780900 |
| helicobacter pylori and extragastric diseases--other helicobacters. | the involvement of helicobacter pylori in the pathogenesis of extragastric diseases continues to be an interesting topic in the field of helicobacter-related pathology. although conflicting findings have been reported for most of the disorders, a role of h. pylori seems to be important especially for the development of cardiovascular and hematologic disorders. previously isolated human and animal helicobacter sp. flexispira and "helicobacter heilmannii" strains have been validated using polyphas ... | 2005 | 16178972 |
| persistent bacterial infections and primary immune disorders. | mycobacteria, salmonella and helicobacter species have all evolved mechanisms to evade host defenses and cause persistent infection in humans. host control of mycobacteria and salmonella is largely achieved by the ifn-gamma/il-12 pathway. immune disorders affecting this pathway are characterized by disseminated infections with environmental or nontuberculous mycobacteria. helicobacter is a predominantly extracellular bacterium that uses its remarkable genetic diversity (as well as other mechanis ... | 2007 | 17208513 |
| immunoblot analysis as an alternative method to diagnose enterohepatic helicobacter infections. | enterohepatic helicobacter species have been associated with chronic infections of the hepatobiliary tract and lower bowel in naturally and experimentally infected mice, helicobacter-infected animals should thus not be used in studies of diseases associated with chronic inflammation. helicobacter species induce inflammation and modulate host immune responses, thus emphasizing the need to diagnose these infections in laboratory animals. | 2009 | 19702846 |
| spatial distribution of helicobacter spp. in the gastrointestinal tract of dogs. | in dogs, the gastric helicobacter spp. have been well studied, but there is little information regarding the other parts of the alimentary system. we sought to determine the spatial distribution of helicobacter spp. in the gastrointestinal tract and the hepatobiliary system of dogs using culture-independent methods. | 2009 | 19702848 |
| chronic hepatitis, hepatic dysplasia, fibrosis, and biliary hyperplasia in hamsters naturally infected with a novel helicobacter classified in the h. bilis cluster. | we recently described helicobacter-associated progressive, proliferative, and dysplastic typhlocolitis in aging (18- to 24-month-old) syrian hamsters. other pathogens associated with typhlocolitis in hamsters, clostridium difficile, lawsonia intracellularis, and giardia spp., were not indentified. the presence of helicobacter genus-specific dna was noted by pcr in cecal and paraffin-embedded liver samples from aged hamsters by the use of helicobacter-specific pcr primers. by 16s rrna analysis, t ... | 2009 | 19759229 |
| pyoderma gangrenosum-like ulcer in a patient with x-linked agammaglobulinemia: identification of helicobacter bilis by mass spectrometry analysis. | pyoderma gangrenosum-like ulcers and cellulitis of the lower extremities associated with recurrent fevers in patients with x-linked (bruton) agammaglobulinemia have been reported to be caused by helicobacter bilis (formerly classified as flexispira rappini and then helicobacter strain flexispira taxon 8). consistent themes in these reports are the difficulty in recovering this organism in blood and wound cultures and in maintaining isolates in vitro. we confirmed the presence of this organism in ... | 2010 | 20479300 |
| could helicobacter organisms cause inflammatory bowel disease? | the discovery of helicobacter pylori sparked a revolution in the understanding and management of peptic ulcer disease and gastric cancer. other helicobacter species are recognized as important pathogenic agents in colitic diseases of rodents and primates, in particular helicobacter bilis, helicobacter fennelliae, helicobacter hepaticus and helicobacter trogontum. helicobacter bilis and h. hepaticus are now routinely used to initiate rodent models of inflammatory bowel disease (ibd), particularly ... | 2010 | 20955468 |
| A Molecular Enrichment Strategy Based on cpn60 for Detection of Epsilon-Proteobacteria in the Dog Fecal Microbiome. | Members of the rare microbiome can be important components of complex microbial communities. For example, pet dog ownership is a known risk factor for human campylobacteriosis, and Campylobacter is commonly detected in dog feces by targeted assays. However, these organisms have not been detected by metagenomic methods. The goal of this study was to characterize fecal microbiota from healthy and diarrheic pet dogs using two different levels of molecular detection. PCR amplification and pyrosequen ... | 2011 | 21881944 |