| motility of mycoplasma pneumoniae. | cell of mycoplasma pneumoniae fh gliding on a glass surface in liquid medium were examined by microscopic observation and quantitatively by microcinematography (30 frames per min). comparisons were made only within the individual experiments. the cells moved in an irregular pattern with numerous narrow bends and circles. they never changed their leading end. the average speed (without pauses) was relatively constant between o.2 and 0.5 mum/s. the maximum speed was about 1.5 to 2.0 mum/s. the mov ... | 1977 | 14925 |
| clinical manifestations due to or associated with mycoplasma pneumoniae infection in adults. | | 1977 | 17904 |
| induction of interferon in mice and cell cultures by mycoplasma pneumoniae. | inoculation of mice and l and human embryonic lung (hel) cell cultures with mycoplasma pneumoniae failed to induce the production of interferon. m. pneumoniae multiplied in these cell cultures without a marked cytopathic effect. m. pneumoniae induced interferon in human peripheral blood leukocytes with maximum titres of 32 units/ml at 48 hours after infection. | 1977 | 23667 |
| exacerbations of chronic bronchitis: exogenous or endogenous infection? | six male patients with chronic bronchitis, who were known previously to have excreted streptococcus pneumoniae and/or haemophilus influenzae, both at the times of exacerbations and during remission, were studied for 43 to 52 months. sputum was examined fortnightly and at the time of exacerbations. strains of strep. pneumoniae were serotyped and those of haemophilus species were typed by antibiograms along with other supporting methods. sera collected before or at the time of an exacerbation and ... | 1978 | 25664 |
| immunochemical studies on a mycoplasma pneumoniae polysaccharide fraction: cross-reactions with type 23 and 32 antipneumococcal rabbit sera. | lipid-free polysaccharide fraction 2 extracted from mycoplasma pneumoniae strain fh by prescott et al. (j. bacteriol. 91:2117-2115, 1966) was examined for its ability to cross-precipitate antibody from type-specific rabbit antipneumococcal sera types 1 to 34 inclusive. cross-precipitation in type-specific pneumococcal anti-type 23 and anti-type 32 sera was examined in detail and could be attributed to a rhamnose-galactose-rich component of crude m. pneumoniae polysaccharide fraction 2 recovered ... | 1978 | 27459 |
| morphological characteristics of acute respiratory tract diseases of mixed etiology in children. | the analysis of 30 etiologically deciphered (by the direct coons method) autopsy observations of acute respiratory diseases in children under 8 is presented. monoinfections were established only in 6 cases. morphological examinations of respiratory organs in 24 cases of mixed acute respiratory diseases (associations of virus-bacteria and virus-mycoplasma pneumoniae-diplostreptococcus) revealed marked circulatory disorders and desquamative, dystrophic, and inflammatory processes in segmental bron ... | 1978 | 28114 |
| the value of immunoelectroosmophoresis (ieop) for etiological diagnosis of acute respiratory tract infections due to pneumococci and mycoplasma pneumoniae. | immunoelectroosmophoresis (ieop) has been used to detect pneumococcal and mycoplasma pneumoniae antigen in 324 sputum samples from 224 patients. pneumococcal antigen was found in 30/37 samples from which pneumococci had earlier been isolated and in 72/243 specimens where they had not been found. of these 72 samples 69 were from patients treated with antibiotics. mycoplasma antigen was found in 9/57 sputum samples from which mycoplasma had been isolated and in 2/32 other samples from patients wit ... | 1978 | 30990 |
| serological diagnosis of pneumococcal disease with enzyme-linked immunosorbent assay (elisa). | antibody response to pneumococcal type-specific polysaccharide was measured with enzyme-linked immunosorbent assay (elisa). the test was shown to be up to 500 times more sensitive than indirect hemagglutination using chromic chloride-treated red blood cells. in 16/17 patients with pneumococcal pneumonia a significant antibody increase was seen as measured with elisa. only 6/23 patients with pneumonia caused by mycoplasma pneumoniae gave a pneumococcal antibody rise and in those cases the increas ... | 1978 | 30991 |
| the microbiology of serous and mucoid otitis media. | one hundred forty-four serous and mucoid effusions were cultured for aerobic bacteria, mycoplasma pneumoniae, and virus. thirty percent of all effusions yielded an unequivocally positive culture for aerobic bacteria. although serous effusions were culture positive as often as mucoid effusions, haemophilus influenzae was isolated predominantly from serous effusions and staphylococcus epidermidis predominantly from mucoid samples. only one of 73 effusions yielded a viral isolate (herpesvirus homin ... | 1979 | 36591 |
| adherence of erythrocytes to mycoplasma pneumoniae. | the human pathogen mycoplasma pneumoniae adheres to a variety of cells, including erythrocytes. a hemadsorption technique was developed to quantitate adherence by photometric measurement of lysates of erythrocytes that attached to sheets of m. pneumoniae grown in cups of linbro plates. attachment of sheep erythrocytes (se) increased with higher ionic strength, was unaffected by minor ph variations (6 to 9), and was blocked by anti-m. pneumoniae antiserum, but was not inhibited by a variety of su ... | 1979 | 39034 |
| adherence of mycoplasma pneumoniae to glass surfaces. | attachment of m. pneumoniae to glass was quantitated in an experimental system enabling the settling down of [3h]palmitic acid-labeled cells onto glass cover slips. attachment of mycoplasmas suspended in buffer increased with temperature, decreased with higher ionic strength, and showed a maximum at about ph 5.5. the findings suggest a participation of ionic bonds in the attachment process. trypsin did not detach glass-bound mycoplasmas, and treatment of the cells with glutaraldehyde did not red ... | 1979 | 40883 |
| pathogenesis of mycoplasma pneumoniae disease. | | 1979 | 44607 |
| autoimmune reactions associated with mycoplasma pneumoniae infection. | patients with mycoplasma pneumoniae infection often develop various autoantibodies including cold agglutinins, cold antibodies reacting with lymphocytes, antibodies against various tissue antigens, for instance brain and lung and smooth muscle antibodies. various mechanisms that may be responsible for the induction of these autoimmune responses and the possible pathogenicity of these autoantibodies are discussed. | 1979 | 44608 |
| a virological and epidemiological study of patients with acute hearing loss. | virological and epidemiological data were examined in thirty-nine patients with acute hearing loss. the hearing loss was unilateral in thirty-one patients and bilateral in eight. there was a history of upper-respiratory-tract infection before onset of deafness in ten of the patients. cases were more common in the autumn, with nineteen of the cases occurring in the 3 months from september to november. about half of the patients were 20-40 years old and half 46-73 years old; only one patient w ... | 1975 | 46953 |
| the skin-reactive antigens of mycoplasma pneumoniae. | guinea pigs experimentally infected with mycoplasma pneumoniae or immunized with the orgnaism in combination with freund's complete adjuvant developed a delayed hypersensitive skin reaction following on intradermal injection of the m. pneumoniae antigen. the amount of protein necessary to produce the delayed skin reaction was as low as 0.01 mug. when the sonicated whole cells were extracted with aqueous acetone, the delayed skin reactivity was found mostly in the acetone insoluble (lipid-deplete ... | 1975 | 50469 |
| ultrastructural study of mycoplasma pneumoniae in organ culture. | the ultrastructure of mycoplasma pneumoniae m129 was studied by using specialized staining methods for thin-section transmission electron microscopy. nucleic acid was shown in the cytoplasmic granules and fibrillar material in the nuclear region. the central filament of the highly structured tip contained basic protein. with one method of fixation, parallel filaments were seen in the central core. m. pneumoniae was enveloped in an extracellular mucoprotein layer that was especially concentrated ... | 1976 | 54354 |
| [metabolism inhibition test for isolation of antibodies to mycoplasma pneumoniae]. | | 1976 | 61320 |
| mucocutaneous reactions during mycoplasma pneumoniae infection. | | 1978 | 76182 |
| mucocutaneous reactions during mycoplasma pneumoniae infection. | | 1978 | 76914 |
| mucocutaneous reactions during mycoplasma pneumoniae infection. | | 1978 | 77406 |
| cold hemagglutinin cross-reactivity with mycoplasma pneumoniae. | convalescent sera from proven cases of infection with mycoplasma pneumoniae, and rabbit antisera to m. pneumoniae and to human erythrocyte glycoprotein contained cold hemagglutinins which were reactive only for human erythrocytes. only the human serum cold agglutinins were inhibited by soluble integral glycoproteins derived from human erythrocyte ghosts by treatment with chloroform-methanol. rabbit antiserum to chloroform-methanol glycoprotein, as well as to m. pneumoniae, fixed complement with ... | 1978 | 83298 |
| interaction of mycoplasma pneumoniae with alveolar macrophages: viability of adherent and ingested mycoplasmas. | guinea pig peritoneal or alveolar macrophages were inoculated with mycoplasma pneumoniae cells. extracellular mycoplasms were killed by complement treatment, and the effect of macrophage action on the number of the remaining viable mycoplasmas was observed. the complement killing was to some extent inhibited by the presence of the macrophages, but the mechanism of this protection remains unknown. opsonized mycoplasmas were ingested, and approximately 98% were killed within 4 h. the killing rate ... | 1979 | 113340 |
| interaction of mycoplasma pneumoniae with human lung fibroblasts: characterization of the in vitro model. | the interaction of pathogenic mycoplasma pneumoniae and host cells was studied in cell cultures of mrc-5 human lung fibroblasts. a comparison of results obtained with fibroblasts in a monolayer format and with hamster tracheal explant cultures indicated that the former can bind significantly larger numbers of mycoplasmas. in addition, the attachment was 96% specific, that is, mediated through a neuraminidase-sensitive receptor on the host cell. uptake of mycoplasmas was directly related to the n ... | 1979 | 113348 |
| interaction of mycoplasma pneumoniae with human lung fibroblasts: role of receptor sites. | the biochemical nature of the neuraminidase-sensitive mycoplasma pneumoniae receptor site on human lung fibroblast cells was studied. purified, mixed sialoglycolipid (ganglioside) preparations from human and bovine tissues did not bind to m. pneumoniae organisms and block their subsequent attachment to fibroblasts. fibroblasts incubated for 24 h in sialoglycolipid solutions to increase the ganglioside content of their membranes did not show increased pathogen attachment when later incubated with ... | 1979 | 113349 |
| cefazolin vs penicillin. | | 1979 | 113571 |
| [involvement of mycoplasma ovipneumoniae in enzootic proliferating interstitial pneumonia in sheep]. | | 1979 | 113871 |
| ciliary membrane alterations occurring in experimental mycoplasma pneumoniae infection. | experimental infection of hamster ciliated tracheal epithelium in organ culture with virulent mycoplasma pneumoniae resulted in the deterioration o ciliary necklaces and an altered distribution of membrane-associated particles on the shafts of the affected cilia. to our knowledge that is the first report of an altered disposition of ciliary membrane-associated particles in response to a specific infectious agent. | 1979 | 113877 |
| carditis associated with mycoplasma pneumoniae infection. | among 560 patients with serologically confirmed mycoplasma pneumoniae infection, 25 (4.5%) had carditis (19 perimyocarditis, 6 pericarditis). during the acute phase 9 patients required intensive care. after an average of 16 months follow-up 11 patients with no previous signs of heart disease still had cardiac symptoms or signs. thus carditis associated with m. pneumoniae infection is a serious disease, having cardiac sequelae more often than has hitherto been supposed. the pathogenesis of the ca ... | 1979 | 113988 |
| complement components (c1, c2, c3, c4) in bronchial secretions after intranasal infection of guinea pigs with mycoplasma pneumoniae: dissociation of unspecific and specific defense mechanisms. | shortly after intranasal infection of guinea pigs with mycoplasma pneumoniae, the titers of the complement components increased significantly in bronchial secretions by the folllowing amounts, compared with the titer of a control group: c1, about 2-fold; c2, 1.6-fold; c3, 17-fold; and c4, 942-fold. histopathological signs of inflammation were not apparent at this time. at 2 weeks after infection, when the titers of complement components in the bronchial secretions were at the level of control va ... | 1979 | 114489 |
| a clinical approach to the choice of antimicrobial agents, case number 10: atypical pneumonia. | | 1979 | 114597 |
| severe mycoplasma pneumoniae infection in otherwise healthy siblings. | | 1979 | 115983 |
| cranial neuropathy, myeloradiculopathy, and myositis: complications of mycoplasma pneumoniae infection. | polymyositis, transverse myelitis, ascending polyneuritis, bilateral optic neuritis, and hearing loss developed in a patient with high complement-fixing antibody titers to mycoplasma pneumoniae. each of her three children had primary atypical pneumonia with isolation of the organism. the neurologic disturbance is thought to represent a postinfectious complication of m pneumoniae infection. | 1979 | 116630 |
| the occurrence and clinical picture of serologically verified mycoplasma pneumoniae infections with emphasis on central nervous system, cardiac and joint manifestations. | | 1979 | 117735 |
| mycoplasma pneumoniae infection and neurological complications. | | 1979 | 118797 |
| in vitro antimycoplasmal activity of mepartricin. | the in vitro antimycoplasmal activity of mepartricin was evaluated on several mycoplasma strains. the results demonstrate that this polyene antibiotic possesses a high efficacy against these microorganisms. | 1979 | 118890 |
| mycoplasma pneumoniae infection in 1978. | | 1979 | 119195 |
| mycoplasma pneumoniae infection in some patients with acute respiratory illnesses. | | 1979 | 119708 |
| [a case of pneumonia due to mycoplasma pneumoniae with bilateral pleural effusion (author's transl)]. | | 1979 | 119817 |
| mycoplasma gliding may be a biased brownian motion. | | 1979 | 119890 |
| growth factors for mycoplasma pneumoniae in yeast and tissue extracts. | | 1979 | 120357 |
| mycoplasma pneumoniae and the aetiology of lobar pneumonia in northern nigeria. | over a six-month period we studied 74 adult nigerians who presented consecutively to ahmadu bello university teaching hospital, zaria, with lobar or segmental pneumonia. pneumococcal infection was diagnosed in 50% by the detection of pneumococcal polysaccharide antigen in serum or purulent sputum: 24% had pneumococcal antigenaemia. twelve patients had evidence of mycoplasma pneumoniae infection and half of these also had pneumococcal infection. the suggestion that m pneumoniae respiratory infect ... | 1979 | 120616 |
| gliding mycoplasmas are inhibited by cytochalasin b and contain a polymerizable protein fraction. | studies are presented on the effect of cytochalasin b (cb) on the growth of five mycoplasma species, three acholeplasma species, and one spiroplasma species. the three gliding mycoplasma species (m gallisepticum, m pneumoniae and m pulmonis are the only mycoplasmas inhibited by cb. these are the only prokaryotes reported to be inhibited by cb. this suggested that these three mycoplasmas might have some sort of cytoskeletal structure. a protein fraction has been isolated from m gallisepticum whic ... | 1979 | 121144 |
| resistance of mycoplasma pneumoniae to macrolide and analogous antibiotics. | 1. the susceptibility of m. pneumoniae to antibiotics can be determined by the microtiter method. the adequate technique requires that the final volume of broth medium in a well is 0.2 ml and that the dilution is made after the parent solution of antibiotic in the test tube is dropped into a well every fifth wells. 2. m. pneumoniae was cultured on agar media containing two-fold concentrations of macrolide and analogous antibiotics, and the following results were obtained. 1) the growth of eight ... | 1979 | 121168 |
| normal values in the adult zambian. (viii). antiviral and mycoplasma antibodies. | | 1978 | 121185 |
| the longitudinal approach to the pathogenesis of respiratory disease. | longitudinal observations were made of a well-defined population of children at a day care center in an investigation of the pathogenesis of infections due to respiratory syncytial virus (rsv) and mycoplasma pneumoniae. a single rsv infection induced a modest but significant degree of resistance to further rsv infection in these children. age and immunity seemed to interact to decrease the intensity of the clinical expression of illness associated with rsv infection. infants and young children h ... | 1979 | 121783 |
| immunity to mycoplasma infections of the respiratory tract: a review. | | 1979 | 121892 |
| comparative evaluation of some methods for detection of m. pneumoniae antibodies. | various methods of detection are available for measuring antibodies specific to m. pneumoniae. we examined over 600 sera of patients with clinical diagnosis of m. pneumoniae infection using complement fixation (cf) test. 91 gave positive reaction and were therefore selected for a comparative analysis with other methods such as metabolic inhibition (mi), mycoplasmocidal (mc) and radioimmunoprecipitation (rip) methods. mc and rip test gave antibody titers comparatively higher than mi and cf. compa ... | 1979 | 121958 |
| [epidemiological and clinical aspects of primary atypical pneumonia]. | | 1979 | 122260 |
| epidemiology of mycoplasma pneumoniae infections. i. age and seasonal distribution of m. pneumoniae antibodies in the population of bucharest. | | 1979 | 122261 |
| mycoplasma pneumonia associated with acute glomerulonephritis. | an 11-year-old girl who presented with pneumonia, pleural effusion, hematuria, and red blood cell casts is described. mycoplasma pneumoniae complement fixation titers were elevated. the pneumonia resolved following therapy with tetracycline. light microscopy of renal biopsy tissue revealed an acute glomerulonephritis; immunofluorescent studies showed deposits of igg, c3 and mycoplasma antigen along the glomerular capillary walls and in the mesangium; subendothelial and subepithelial deposits wer ... | 1978 | 152413 |
| [distribution of respiratory viruses and mycoplasma pneumoniae among the population of the abkhaz assr from 1971 to 1975]. | | 1979 | 154815 |
| the tecumseh study of respiratory illness. viii. acute infection in chronic respiratory disease and comparison groups. | individuals with chronic lung disease and their families were selected from the tecumsch community along with similarly selected families as comparison groups and studied for 1-year periods. occurence of acute respiratory illness was ascertained weekly by telephone and calculated as an annual rate. persons with chronic bronchitis not only experienced more acute lower respiratory illness than healthy comparison subjects, but total illness rates were somewhat higher as well. infection rates were d ... | 1975 | 163065 |
| the protean manifestations of mycoplasma pneumoniae infection in adults. | mycoplasma pneumoniae is a well recognized respiratory pathogen in children and young adults. in addition, m. pneumoniae infections may also involve other organ systems. reviewed here are the various clinical syndromes in adults caused by this infectious agent, with emphasis on those which have recently been seen at the new york hospital. two previously unreported manifestations of m. pneumoniae infection, cranial nerve mononeuropathy and hepatitis, are described, and the laboratory methods for ... | 1975 | 163580 |
| effect of mycoplasma pneumoniae on poliovirus replication. | results are presented which indicate that different species of mycoplasma may have varying effects on the replication of different viral types. | 1975 | 163801 |
| virus antibody levels in serum specimens from patients with optic neuritis and from matched controls;. | virus antibody levels in serum specimens taken in acute and convalescent phases from 77 patients with optic neuritits were tested by measles hamagglutination inhibition (hi), measles hemolysis inhibition (hli), rubella hi, parainfluenza-1 hi, epstein-barr immunofluorescence (if), and against 11 other viruses and mycoplasma pneumoniae with the complement fixation (cf) technique. the virus antibody levels were indicated to be usually very stable, and a fourfold change in virus antibody levels was ... | 1975 | 165652 |
| virus antibody levels in the cerebrospinal fluid from patients with optic neuritis. | virus antibody levels were studied in the cerebrospinal fluid (csf) of 58 patients with optic neuritis and 58 control patients with no indication of multiple sclerosis (ms) or infectious disorders of the central nervous system (cns). the specimens were tested against three different structural components of measles virus with measles hemagglutination inhibition (hi), measles hemolysis inhibition (hli) and gel precipitation (gp) tests. measles antibodies occurred in 62 per cent of csf specimens f ... | 1975 | 165653 |
| serologic profile of children in a mexican highland community: prevalence of complement-fixing antibodies to mycoplasma pneumoniae, respiratory syncytial virus and parainfluenza viruses. | the study investigated the prevalence of antibodies to five leading agents of childhood respiratory disease in the county of huixquilucan, mexico. tests of sera from a random sample of children between 3 months and 18 years of age confirmed serologically the presence of mycoplasma pneumoniae, respiratory syncytial (rs) virus and parainfluenza 1, 2 and 3 viruses in this relatively isolated highland community. highest overall antibody frequency of 64.2% was seen for parainfluenza 3, and antibody t ... | 1975 | 165720 |
| the seattle virus watch. vi. observations of infections with and illness due to parainfluenza, mumps and respiratory syncytial viruses and mycoplasma pneumoniae. | seattle virus watch families were observed, 1965-1969, for infections with paramyxoviruses and m. pneumoniae by agent isolation and antibody assay of serial sera. infection rates, based on serology, exceeded those in tecumseh where families contained fewer young children. rates per 100 person-years were 44.4 for parainfluenzavirus, 21.6 for respiratory syncytial (rs) virus and 12.3 for m. pneumoniae. preschool children experienced the highest rates for rs and parainfluenza-viruses but, for the l ... | 1975 | 168766 |
| serologic studies of acute respiratory infections in military personnel. | the advantages, disadvantages, and uses of serological epidemiology are discussed in relation to acute respiratory infections in military personnel. the prevalence of antibody reflects both current and past experience with respiratory agents and is a measure of susceptinility. incidence data calculated by testing two serial serum samples, on entry and discharge from the service, has indicated high influenza and mycoplasma pneumoniae rates in south american recruits and low rates of adenovirus ... | 1975 | 169640 |
| viruses and the aetiology of diabetes: a study in identical twins. | sera were collected from 49 pairs of identical twins, 27 of whom were discordant (only one twin affected) and 22 concordant (both diabetic) for insulin-dependent diabetes. all were tested for antibodies to mumps, cytomegalovirus, rubella, coxsackie virus types b1-5, and mycoplasma pneumoniae. the diabetic co-twins had no more antibodies to any of the viruses than the non-diabetic co-twins of the discordant pairs. antibodies to coxsackie b2, rubella virus, and m pneumoniae were found more often i ... | 1975 | 172183 |
| attachment of mycoplasma pneumoniae to respiratory epithelium. | the attachment of radioisotope-labeled mycoplasma pneumoniae to hamster tracheal rings in organ culture was examined by radioautography and liquid scintillation counting. radioautographs of individual rings exposed for 8 h to (3h) thymidine-labeled virulent m. pneumoniae revealed a dense extracellular collection of emulsion grains along the luminal surface of epithelial cells. similar exposure of rings to isotope-labeled avirulent m. pneumoniae resulted in no accumulation of emulsion grains. the ... | 1976 | 178600 |
| acute facial palsy. some clinical and virological observations. | a prospective clinical and virological study on 44 patients with acute, peripheral facial paralysis was carried out in consecutive cases during one year. in 9 cases varicella-zoster infections were serologically established. in 5 additional patients an associated varicella-zoster, or herpes simplex, infection was possible. of the 9 confirmed cases, 6 were clinically diagnosed as zoster oticus, whereas on clinical grounds, 3 were regarded as bell's palsy. no evidence was obtained of associated en ... | 1976 | 179268 |
| [aetiological studies on viral pneumonia (author's transl)]. | 401 cases of viral pneumonia diagnosed between january 1973 and august 1975 were investigated serologically by the complement-fixation test. the percentage distribution of the responsible pathogenic organism in this series of cases was as follows: influenza virus a 45.9%, mycoplasma pneumoniae 19.5%, coxsackie b viruses 9.2%, cytomegalovirus 7.5% and chlamydia psittaci 8.5%. the remaining 9.4% cases were caused by adeno, parainfluenza, measles, influenza b, herpes simplex and respiratory syncyti ... | 1976 | 185813 |
| [atypical pneumonia, etiology and possibilities for the diagnosis (author's transl)]. | beginning with the antimicrobial chemotherapy a decrease in the incidence of bacterial pneumonias is accompanied by a relative increase in the incidence of the so-called atypical pneumonia. this disease syndrome is predominantly caused by mycoplasma pneumoniae, chlamydia psittaci, coxiella burneti and various viruses. in addition, bacteria which are usually involved in lobar pneumonia may occasionally cause atypical pneumonias. the present publication is concerned with the most frequently occurr ... | 1976 | 186398 |
| [neurologic manifestations in mycoplasma pneumoniae. apropos of 12 cases]. | specific serological methods now enable us to demonstrate that mycoplasma pneumoniae is responsible for a variety of neurological symptoms. we describe 12 new cases: 2 encephalites, 8 diffuse polyradiculoneurites and 2 isolated lesions of the cranial nerves. these 12 cases, together with the 42 recorded in the literature, bring total number of published cases to 54. analysis emphasizes the extreme polymorphism of the neurological manifestations and their favourable prognosis in most cases, howev ... | 1976 | 188091 |
| virus antibody levels in iga deficiency. | iga-deficient blood donors and their age- and sex-matched controls were compared for the occurrence of complement-fixing antibodies in serum against several viruses. the level in the iga-deficient persons was slightly higher against several respiratory pathogens (adenoviruses, type b influenza virus, parainfluenza virus, and respiratory syncytial virus) that give rise to localized infections, and against coxsackie b group of viruses. no corresponding difference was observed in mumps, varicella, ... | 1976 | 189383 |
| viral, mycoplasma and bacterial infections in nurses with symptoms of respiratory diseases. | a consecutive series of 282 nurses of the university hospital, groningen, with complaints of the nose and/or throat associated with coughing and/or hoarseness were examined between april 1965 and february 1968. the intent was to obtain information on the incidence of viral, mycoplasma and bacterial infections, and on the relationship of these infections in nurses with chronic nonspecific lung disease (cnsld). the following results were obtained: 1. virus infections caused by influenza virus (a, ... | 1976 | 189386 |
| [the fixing complement antibodies to respiratory viruses--influenza a1, b, c, parainfluenza 1 (sendai), syncytial respiratory, adenovirus, echo 11--and "mycoplasma pneumoniae" in healthy persons (author's transl)]. | serological research of complement fixation test (kolmer micromethod) into 163 young healthy subjects (18-22 years old) in order to point out the contaminations effects of respiratory viruses and of mycoplasma pneumoniae. in is pointed out serological simultaneous reactions on some subjects, expression of multiple infections; the different frequency of serological tests for each antigen, pointing out the rôll played by the singles diseases, the different titre distribution of the antibodies to 1 ... | 1976 | 190954 |
| [etiology of acute respiratory infection in hospitalized children (author's transl)]. | incidence of respiratory tract infection represents 23% of the total number of admissions between 1-24 months of age, during a period of 18 months. the diagnosis were: bronchiolities, 143 cases; bronchopneumonia, 134 cases; tracheobronchitis, 50 cases; laryngitis, four cases, and bacterial pneumonia, 61 cases. monthly incidence was maximal in december of each year. from the total group, 144 cases were included in the present study to determine etiology of the infection. in 19% of the cases a ser ... | 1976 | 193420 |
| simple mathematical deductions in the seroepidemiology of viral infections. ii. (para) myxoviruses (measles, mumps, influenza b), rubella, enteroviruses (polio, coxsackie b), adenoviruses, and mycoplasma pneumoniae. | large samples of nonselected persons collected in south-west germany were investigated for the prevalence of serum antibodies to poliovirus 1-3 and coxsackievirus b 1-5 (neutralisation test), to measles, rubella, and mumps (hemagglutination inhibition test), mumps, influenza b, adenovirus, and mycoplasma pneumoniae (complement-fixation test). according to "catalytic models", which compare the infection spread to simple chemical reactions of molecules as self-limiting procedures, a mathematical a ... | 1977 | 196454 |
| correlation of exposure to various respiratory pathogens with farmer's lung disease. | complement-fixing antibodies (cfa) to a panel of microorganisms commonly associated with respiratory disease were measured in a number of agricultural populations. the panel included mycoplasma pneumoniae, influenza viruses a and b, parainfluenza virus types 1, 2, and 3, adenovirus, and respiratory syncytial virus. the agricultural populations were grouped according to a clinical history of farmer's lung disease (fld) and the presence of antibodies to the thermophilic actinomycetes (ta). farmers ... | 1977 | 197136 |
| aseptic meningoencephalitis, a complication of mycoplasma pneumoniae infection. | | 1977 | 200647 |
| infections with viruses and mycoplasma pneumoniae during exacerbations of chronic bronchitis. | the association of viral and mycoplasma pneumoniae infections with acute exacerbations of chronic bronchitis was studied by serologic or isolation techniques in 46 adult men during the five years from 1964 through 1968. serologic evidence of viral or m. pneumoniae infection was detected in 25% of 166 episodes of exacerbation and 14% of 138 remission periods (p = 0.02). influenza a virus, parainfluenza virus type 3, and coronavirus oc43 predominated; infections with other viruses were infrequent. ... | 1978 | 206630 |
| infections and other maternal factors as risk indicators for congenital malformations: a case-control study with paired serum samples. | an obstetric population of 48,000 individuals was prospectively followed up for evidence of possible teratogenic factors that might be associated with congenital malformations. serum samples from 274 mothers of defective children and from paired controls were collected during early pregnancy and approximately one month after delivery and tested for antibodies against ten different viruses, mycoplasma pneumoniae, and toxoplasma. these data were supplemented with clinical information on infections ... | 1978 | 209394 |
| [role of parainfluenza viruses rs and adenoviruses as well as mycoplasma pneumoniae in acute respiratory infections in infants]. | | 1978 | 211553 |
| relationship of herpes simplex virus type-2 antibodies and squamous dysplasia to cervical carcinoma in situ. | serum specimens from 75 women with cervical carcinoma in situ, 84 with squamous dysplasia, and 132 controls, who had previously been interviewed and tested for complement fixing antibodies against a number of organisms, were analyzed for hsv-2 antibodies. carcinoma in situ and severe dysplasia were associated with hsv-2 antibodies. mild dysplasia was related to evidence of prior infection by trichomonas vaginalis, adenoviruses, and mycoplasma pneumoniae, plus a history of vaginal discharge. seve ... | 1978 | 215294 |
| effect of in vitro cultivation and mycoplasma pneumoniae infection on intracellular cyclic amp levels in hamster tracheal organ cultures. | exogenous cyclic amp and dibutyryl cyclic amp decreased the relative ciliary activity values of tracheal organ cultures. in contrast, theophylline and cholera toxin were not ciliostatic. the use of a radioimmunoassay for cyclic amp indicated that all of the tested substances increased intracellular cyclic amp levels to some extent (from 3-fold for cholera toxin to almost 40-fold for dibutyryl cyclic amp). physical inactivation of explants by either freeze-thaw or heat destroyed all ciliary activ ... | 1979 | 222670 |
| immobilization of viral and mycoplasma antigens and of immunoglobulins on polystyrene surface for immunoassays. | the immobilization of purified influenza virus, rubella virus, crude nuclear cytomegalovirus antigen and of mycoplasma on polystyrene tubes was studied using radio-iodinated preparations. the antigen activities on tube surfaces were determined using sequentially specific human antibodies and alkaline phosphatase-conjugated anti-human igg in an enzyme-immunoassay (eia) reaction. in addition, immobilization of radio-iodinated human igg, igm, and iga, serving as model proteins, was studied using th ... | 1979 | 227962 |
| [role of respiratory viral infections and mycoplasma pneumoniae infection among the occasional factors in non-tuberculous spontaneous pneumothorax. apropos of a serological inquiry into 91 cases]. | | 1978 | 228808 |
| lipoproteins as substitutes for serum in mycoplasma culture medium. | crude lipoprotein-containing fractions obtained from sera of three different animal species were tested, in combination with bovine serum in mycoplasma pneumoniae culture medium. all sera yielded at least one lipoprotein-containing component which was considerably more effective in promoting mycoplasma growth than the unfractionated serum sample from which it was derived. the very low activity of certain whole-serum samples tested in this investigation suggests that toxic substances may be prese ... | 1979 | 231051 |
| a study of infections and illnesses in a day nursery based on inclusion-bearing cells in the urine and infectious agent in faeces, urine and nasal secretion. | during an epidemic-free period of nearly 2 years infections and illnesses were followed in a group of small children (2-3 1/2 years) in a day nursery. the incidence of illness was fairly low, 6.3 per child and year. the viral infections were followed by means of the inclusion reaction in the urine and isolation of virus, and the bacterial by culture of nasal secretion. in 60% of the cases the viral infection was accompanied by illness. in 57 cases of illness there were 27 (47%) with merely virus ... | 1979 | 231298 |
| activities of enzymes of purine and pyrimidine metabolism in nine mycoplasma species. | | 1979 | 232630 |
| [incidence of mycoplasma pneumoniae infections in the western districts of the county of karl-marx-stadt in the period from 1973 to 1977]. | | 1979 | 232950 |
| [serological survey for virus and mycoplasma infections (author's transl)]. | the authors describe the two years follow up of complement fixing antibodies vs 4 viral antigens (herpes simplex, herpes zoster, cytomegalovirus, respiratory syncytial virus, mycoplasma pneumoniae). they evaluate the seasonal trend and the eventual clinical correlations on 3267 sera and 254 spinal fluids from hospitalized patients. | 1979 | 233415 |
| megaloblastic arrest in hemolytic anemia due to mycoplasma pneumoniae infection. | | 1975 | 237828 |
| hemolytic anemia. associated with severe mycoplasma pneumoniae pneumonia. | | 1978 | 281612 |
| incidence of mycoplasma pneumoniae infection. | | 1978 | 282500 |
| [clinical evaluation of clindamycin-2-phosphate in infectious diseases (author's transl)]. | clindamycin-2-phosphate (7(s)-chloro-7-deoxylincomycin-2-phosphate) is a new semi-synthetic antibiotic. it is recognized that the drug itself is inactive against bacteria in vitro but it is hydrolyzed rapidly to active clindamycin, drug intramuscular or intravenous administration. clindamycin-2-phosphate was administrated intravenously to seven patients with infections, except one intramuscularly, 300 approximately 600 mg, every 8 or 12 hours a day, for 2 approximately 12 days. three patients (1 ... | 1977 | 320361 |
| viral antibodies in the sera from patients with parkinson disease. | an assay of antibodies to 15 various viruses and mycoplasma pneumoniae was performed on the serum specimens from 441 patients with parkinson disease and from 443 healthy controls matched by sex, age, and place of residence, or from a representative group of these matched pairs. the main finding was a higher herpes simplex complement-fixing antibody level in patients with parkinson disease than in controls. patients with parkinson disease had higher herpes simplex antibody titers more often than ... | 1977 | 323017 |
| unexpectedly high frequency of antibody to mycoplasma pneumoniae in human sera as measured by sensitive techniques. | mycoplasmacidal and radioimmunoprecipitating antibodies to mycoplasma pneumoniae were commonly detected in healthy children younger than five years of age, in whom natural disease due to m. pneumoniae is rare. antibody in serum could also be demonstrated in marine recruits several weeks or months before development of pneumonia due to m. pneumoniae. the latter observation suggests that serum antibody does not confer protection against disease caused by m. pneumoniae. | 1977 | 323374 |
| extraction of an actin-like protein from the prokaryote mycoplasma pneumoniae. | an actin-like protein has been identified in cell extracts from the prokaryote mycoplasma pneumoniae. this protein bears a striking resemblance to actin from vertebrates: (i) the solubility of the protein during isolation is analogous to that of actin bound to myosin (soluble in high ionic strength salt solution and insoluble at low ionic strength), (ii) sodium dodecyl sulfate treatment of the partially purified m. pneumoniae extract produces a protein with an electrophoretic mobility very close ... | 1977 | 333456 |
| [study of antibiotic sensitivity in 34 strains of large colony mycoplasma (author's transl)]. | the application of steer's technic to large colony mycoplasma for the study of antibiotic sensitivities, permitted us to compare the activity of various molecules inhibiting protein synthesis. among large colony mycoplasmas, only mycoplasma pneumoniae is sensitive to erythromycin but we have already isolated a strain resistant at 400 microgram/ml. this should be remembered during treatment of mycoplasma pneumoniae infections. this species always remains sensitive to tetracycline. among the latte ... | 1977 | 339167 |
| activation of human lymphocyte subpopulations by mycoplasma pneumoniae. | b- and t-cell-enriched preparations of lymphocytes from human blood (5 cases), adenoids (10 cases), and tonsils (4 cases) were examined for the in vitro stimulation response to mycoplasma pneumoniae (mp). b lymphocytes did not respond to mp by dna synthesis except for the b cells from one adenoid. t lymphocytes and nonfractionated lymphocytes from blood, from three of the adenoids and two of the tonsils showed a stimulation response to mp. nonfractionated adenoid lymphocytes from altogether 22 c ... | 1977 | 339326 |
| [illness due to mycoplasma pneumoniae in childhood (author's transl)]. | mycoplasma pneumoniae infection could be found in 16 from 92 children treated for respiratory disease in a hungarian hospital. it was verified by growth inhibition test or by culturing germs from bronchial secretions. seroology proved to be more effective than culture for identification. illnesses due to mycoplasma pneumoniae seem to be more frequent in the age group 0--3 years in hungary than they are in western countries in the same age group. the authors assume that this high frequency is cau ... | 1977 | 339560 |
| erythema multiforme and the stevens-johnson syndrome. | erythema multiforme (em) is clinically characterized by a "minor" form and a "major" form. the latter is known as the stevens-johnson syndrome. infections (particularly herpes simplex and mycoplasma pneumoniae) and drugs seem to predispose toward the development of em. the pathogenesis is poorly understood. the treatment is supportive. prognosis varies with the severity of the eruption. recurrences are commonly seen. | 1978 | 347587 |
| a study of acute respiratory disease in the community of port chalmers. i. illnesses within a group of selected families and the relative incidence of respiratory pathogens in the whole community. | a study of respiratory diseases in the semi-isolated community of port chamlers, new zealand, began in april 1973. the intensive surveillance of a selected group fo 26 families involved the weekly reporting of illness, the collection of specimens for virus, group a streptococci and mycoplasma pneumoniae isolation and the collection of sera at 6-month intervals. a total of 956 illnesses were reported during 32 months. the median number of illnesses per year were: infants 4.4, children 2.5, female ... | 1978 | 357651 |
| the clinical spectrum of mycoplasma pneumoniae infections. | | 1978 | 366298 |
| incidence and titres of smooth-muscle antibodies in human sera. | by means of the indirect immunofluorescence method smooth-muscle antibodies (sma) were determined in 182 patients with various diseases and the findings were compared with those of 7 patients with chronic active hepatitis (cah) and 580 normal controls. igg-sma were found in 85.7% of the patients with cah, titres above 80 occurred only in hepatitis b-associated antigen (hbag)-negative cah, but igg-sma in low titres were also found with increased incidence in syphilis (16.7%) and in infections of ... | 1979 | 373382 |
| enhanced isolation of mycoplasma pneumoniae from throat washings with a newly-modified culture medium. | two hundred throat washings, previously screened and presumed negative for mycoplasma pneumoniae in conventional mycoplasma culture media, were retested for the organism in a modified medium (ps-4) initially developed for cultivation of a tick-derived mycoplasma (spiroplasma). the organism was rapidly identified with an agar plate immunofluorescence procedure. m. pneumoniae was isolated from 69 (34.5%) of the 200 "negative" specimens cultured on a diphasic sp-4 medium, in contrast to 10 isolatio ... | 1979 | 374649 |
| experimental mycoplasma pneumoniae infection of marmosets. | | 1977 | 403371 |