| disseminated nocardia caviae infection. | disseminated nocardia caviae infection occurs only rarely. to date, two cases have been recorded in the literature. we describe a third case of systemic n. caviae infection in a compromised host and compare it with the first two cases. postmortem, microbiologic and antibiotic sensitivity data are included. | 1977 | 320868 |
| disseminated nocardia caviae with positive blood cultures. | disseminated nocardia caviae infection with multiple positive blood cultures occurred in a bone marrow transplant recipient. positive blood cultures are unusual in disseminated nocardia infections and n caviea is an unusual species of nocardia to cause infections in man, although its virulence in laboratory animals is similar to n asteroides. multiple positive blood cultures in this case suggest a continuous or recurrent bacteremia rather than a transient bacteremia as previously has been though ... | 1978 | 352297 |
| different degrees of morbidity, in the white mouse, induced by nocardia brasiliensis, nocardia asteroides and nocardia caviae. | the respective degrees of morbidity induced by 6 strains each of nocardia brasiliensis, n. asteroides and n. caviae were investigated by the method of inoculation in the plantar pad of the white mouse, using a suspension of these nocardiae at a concentration of 10 mg/0-1 ml., and inspecting the animals one month, two months and three months following inoculation. all of the strains of n. brasiliensis produced attack greater and more consistent than that of the other species, n. caviae and n. ast ... | 1976 | 793053 |
| [characterisation of d(-)glyceric acid from nocardia caviae (author's transl)]. | a glycolipid was found in a strain of nocardia caviae. it consists of glucose, myristic, palmitic and stearic acids and a polyhydroxylated acid. the structure of this hydroxyacid was demonstrated by the identification of the product glycerol after lia1h4 reduction of the glycolipid methyl ester and subsequent hydrolysis, by comparison of the infrared spectra of the hydroxyacid and glyceric acid, by gas chromatography of acetylated methyl and ethyl esters of the polyhydroxylated acid and of stand ... | 1976 | 952993 |
| localized nocardiosis due to nocardia caviae in a baboon (papio cynocephalus). | nocardia caviae was identified as the causative agent of draining, multinodular swelling of the hand of a 16-yr-old female baboon (papio cynocephalus). the baboon's general physical condition was poor and menstrual cycles had ceased. the baboon improved after systemic and topical antibiotic therapy, but the lesion recurred after antibiotic treatment was discontinued. since excision of the mass, the baboon's physical condition has improved to the extent that regular menstrual cycles have resumed ... | 1975 | 1121169 |
| mycetoma of the knee due to nocardia caviae. | mycetoma of the knee, caused by nocardia caviae and idangosed by culture and histopathology, occurred in a 20 year old farmer from a rural area of varanasi district in uttar pradesh, india. the isolate was pathogenic to mice and it showed close agreement with the standard description of the species. it is suggested that infection due to this species has a higher prevalence than is currently recognized. | 1975 | 1162539 |
| review of nocardial infections in france 1987 to 1990. | on the basis of the numbers of nocardia strains referred to the national reference center for mycoses and antifungal agents (nrc), institut pasteur, paris, in the period from 1987 to 1990, it was estimated that between 150 and 250 cases of nocardiosis are diagnosed in france each year. a total of 63 clinical isolates were referred to the nrc and identified as nocardia asteroides (66.7%), nocardia farcinica (23.8%), nocardia brasiliensis (3.2%), nocardia otitidiscaviarum (4.8%) and nocardia carne ... | 1992 | 1425729 |
| light and electron microscopic studies on experimental nocardia-toxicosis in mice. | an exotoxin (hs-6) produced by nocardia otitidiscaviarum isolated from certain lesions of cutaneous nocardiosis of a male 82-year-old patient induced severe injuries in the pancreas, liver, stomach, small intestine, heart, thymus and kidney of male icr mice. mice given nocardia-free preparation of hs-6 at a dose of 1 mg/kg of body weight developed several autophagic vacuoles in the pancreas and liver within 20 min after the i.p. injection. thereafter, the autophagic vacuoles increased in number ... | 1992 | 1435948 |
| nocardia otitidiscaviarum (caviae) infection in a heart transplant patient presented as having a thigh abscess (madura thigh). | the first case of disseminated infection with nocardia otitidiscaviarum in a heart transplant patient is reported. the clinical spectrum and treatment of infections with n. otitidiscaviarum is discussed, including our patient's apparent response to imipenem/cilastatin. | 1992 | 1498150 |
| in-vitro activity of new carbapenem antibiotics: comparative studies with meropenem, l-627 and imipenem against pathogenic nocardia spp. | mics of two new carbapenems, meropenem and l-627, and imipenem were determined against 98 strains of the nocardia asteroides group (i.e. n. asteroides sensu stricto, nocardia farcinica and nocardia nova), 46 strains of nocardia brasiliensis and 17 strains of nocardia otitidiscaviarum. meropenem and l-627 were less active against the n. asteroides group than imipenem. among the three species of the n. asteroides group, n. nova was the most sensitive to all the carbapenems. meropenem was more acti ... | 1992 | 1506332 |
| septic arthritis due to nocardia caviae. | | 1991 | 1768177 |
| mycetoma due to nocardia caviae--a case report. | | 1991 | 1794911 |
| acid and alkali as aids in differentiation of pathogenic nocardia and for their isolation from clinical specimens. | the tolerance of nocardia brasiliensis, nocardia asteroides and nocardia caviae to different concentrations of acids and alkalis was studied in this work. the purpose was to determine their use: (a) in the differentiation of species; (b) for decontamination of clinical materials during the isolation of pathogenic nocardia. the results showed (1) that both 2 m nh3 and 0.05 m h2so4 solutions are useful for differentiating species. they can also be used as a complementary method for identification. ... | 1991 | 2067559 |
| [nocardia caviae meningitis in a patient with hiv infection]. | | 1990 | 2091125 |
| comparison of antigens from agents of actinomycetoma by immunodiffusion and electrophoresis procedures. | antigenic extracts were prepared from culture filtrates of the principal agents known to cause actinomycetoma, namely actinomadura madurae, actinomadura pelletieri, nocardia asteroides, nocardia brasiliensis, nocardia otitidis-caviarum, and streptomyces somaliensis. these antigenic preparations were compared by immunodiffusion (id), counterimmunoelectrophoresis (cie), line immunoelectrophoresis (lie) and rocket line immunoelectrophoresis (rlie), with rabbit antisera prepared against each of the ... | 1990 | 2126557 |
| a toxic substance produced by nocardia otitidiscaviarum isolated from cutaneous nocardiosis. | during our studies on toxic substances from clinically isolated nocarida, a new isolate identified as nocardia otitidiscaviarum from cutaneous nocardiosis was found to produce a toxic substance called hs-6 that had strong in vitro as well as in vivo toxicity. the mouse intraperitoneal ld50 value was 1.25 mg/kg and the ed50 value for l1210 cultured cells was 0.3 ng/ml. the structure of hs-6 was determined and found to belong to the 16-membered macrocyclic group with a molecular formula of c43h68o ... | 1990 | 2293032 |
| the efficiency of 1 m nh4cl and 2 m nacl for the isolation of pathogenic nocardia from soil. | the present paper reports an improvement to the classical method of the paraffin bait, by the usage of 1 m nh4cl or 2 m nacl to eliminate contaminant microflora of soil. the purpose is to introduce a change in the paraffin bait method in order to reduce time required to isolate pathogenic strains of nocardia from their natural sources. for this study three main criteria were used: a) determination of the inhibitory effect of different concentrations of salts on soil microflora; b) the tolerance ... | 1989 | 2594047 |
| [nocardiosis: clinical observations apropos of 9 cases]. | we have retrospectively analyzed 9 cases of nocardiosis that were studied in our hospital over the past 10 years. 66% of the patients had an associated disease and half of them were on steroid treatment. the clinical manifestations of the infection were pulmonary and cutaneous and in 44% of cases, it disseminated to the central nervous system. the diagnosis was made in all cases isolating the microorganism from pulmonary secretions, puss, spinal fluid and blood. nocardia asteroides was isolated ... | 1989 | 2623279 |
| brain abscess due to nocardia. | cerebral nocardiosis is a rare disease, usually occurring in immunocompromised hosts. we report here two cases of brain abscess due to nocardia species-one due to usual n. asteroides and other by uncommon n. caviae. n. asteroides affected the brain in a post renal transplant patient, whereas n. caviae caused infection of brain in an apparently healthy individual. to the best of our knowledge, all the previous cases of brain abscess due to nocardia caviae have been reported in compromised hosts. ... | 1989 | 2693966 |
| primary subcutaneous abscess caused by nocardia otitidiscaviarum. | | 1989 | 2745762 |
| size and homology of the genomes of leprosy-derived corynebacteria, mycobacterium leprae, and other corynebacteria and mycobacteria. | the genomes of mycobacterium leprae and leprosy-derived corynebacteria (ldc), which have a similar base composition of guanine + cytosine 56 mol %, have been compared with those of reference bacteria of the cmn group (genera corynebacterium, mycobacterium, nocardia). genome sizes of three ldc strains were (1.2-2.5) x 10(6) base pairs. dna from four of seven ldc strains examined had homology levels greater than 60%. two other strains had a homology of 40% when compared with the cmn strains and on ... | 1988 | 3050108 |
| in vitro susceptibilities of nocardia species to newer antimicrobial agents. | the in vitro activities of various quinolones, two newer cephalosporins, and imipenem against 23 strains of nocardia asteroides, 4 strains of nocardia brasiliensis, and 4 strains of nocardia caviae were determined by an agar dilution method. pd-117558, a newer carboxyquinolone, and imipenem were the most active agents tested, inhibiting 90% of n. asteroides isolates at an mic of 2 micrograms/ml. of the 23 strains of n. asteroides, 15 were susceptible to cefpirome and 10 were susceptible to cipro ... | 1988 | 3190193 |
| pulmonary infection with nocardia caviae in a patient with diabetes mellitus and liver cirrhosis. | the first reported case of pulmonary infection with nocardia caviae in britain occurred in a 67 year old woman, in whom diabetes mellitus and liver cirrhosis probably contributed to impaired cell mediated immunity. she was successfully treated with gentamicin 60 mg eight hourly and sulphadimidine 500 mg six hourly for six months and then with sulphadimidine 2 g/day for a further three months. when nocardia caviae is isolated from the sputum of a patient with chronic respiratory infection and fev ... | 1988 | 3222767 |
| mycetoma due to nocardia caviae. | mycetoma is the most frequent deep mycosis in mexico and is caused by nocardia brasiliensis in 86% of the cases. two cases of mycetoma due to nocardia caviae, the first in mexico, are reported. the strains were identified by their biochemical properties according to the criteria of gordon and mihm (1962). few cases of mycetoma caused by this actinomycete have been reported in the world. one of our cases was unusual: occurring on the trunk as a tumor and diagnosed by finding the "grains" on histo ... | 1987 | 3494691 |
| primary cutaneous nocardiosis due to nocardia caviae. | | 1987 | 3567798 |
| the second case of mycetoma due to nocardia caviae in israel. | a second case of actinomycetoma due to nocardia caviae contracted in israel is reported. a 39-year-old female of yemenite origin, resident in israel for more than 15 years, presented with a sclerotic tumor mass on the dorsum of the right foot which discharged an oily purulent fluid containing minute yellowish granules. seen in the microscopic examination of smears were thin gram-positive filaments and bacillary elements. culture of the crushed granules yielded small pale colonies identified as n ... | 1986 | 3713800 |
| isolation and characterization of an o-methylglucose-containing lipopolysaccharide produced by nocardia otitidis-caviarum. | the low-mr lipopolysaccharide produced by nocardia otitidis-cavirum is composed of 6-o-methyl-d-glucose (11 mol), d-glucose (8 mol) and 3-o-methyl-d-glucose (1 mol). glyceric acid was also found as a constituent. methylation and periodate oxidation analyses suggested that the backbone was formed by (1----4)-linked glucose and o-methylglucose residues. glucose (1 mol) and 6-o-methylglucose (1 mol) served as branching points. acetic acid was the major acyl substituent esterifying glucose residues. ... | 1986 | 3794652 |
| actinomycetoma pedis caused by nocardia caviae in india. | | 1972 | 4553712 |
| nocardia caviae: a report of 13 new isolations with clinical correlation. | thirteen isolates of nocardia caviae from 12 different clinical sources were received and identified over a 5(1/2)-year period by the mycology division of the center for disease control. the results of morphological, biochemical, and physiological studies on these isolates were compared with those obtained with four reference cultures of n. caviae received from the institute of microbiology, rutgers university. comparison showed that n. caviae isolates form a homogeneous group that is usually ea ... | 1974 | 4604822 |
| systemic nocardia caviae infection. | | 1974 | 4813848 |
| nocardia caviae and nocardia asteroides: comparative bacteriological and mouse pathogenicity studies. | | 1971 | 5090889 |
| pathogenicity of nocardia caviae, n. asteroies and n. brasiliensis. | | 1970 | 5455791 |
| a rapidly fatal infection caused by nocardia caviae in a dog. | | 1968 | 5690076 |
| [study on 20 strains of nocardia asteroides and nocardia caviae of different sources]. | | 1968 | 5724277 |
| canine nocardiosis due to nocardia caviae. | | 1968 | 5754802 |
| [note on a mycetoma due to nocardia caviae seen in japan]. | | 1965 | 5898569 |
| determination of sensitivity and specificity of the nocardia asteroides skin test for detection of bovine mammary infections caused by nocardia asteroides and nocardia caviae. | a total of 116 cows from 4 dairy herds in california were used to determine the sensitivity and specificity of extracellular antigen of nocardia astero des for possible detection of bovine mastitis caused by n asteroides and n caviae. three different positive criteria were used. these criteria gave different sensitivity and specificity to the skin test. the highest sensitivity of 80% and highest specificity of 96.04% were obtained by combining 2 criteria. the study found no cross-reaction betwee ... | 1982 | 6178326 |
| [experimental pathogenicity of isolates of nocardia asteroides, nocardia brasiliensis and nocardia caviae from different sources]. | the experimental pathogenicity of 14 isolates of nocardia brasiliensis, 15 of n. asteroides, and 5 of n. caviae was investigated for the white swiss mice inoculated intraperitoneally and in the foot pad, and for the guinea-pig and the hamster (mesocricetus auratus) both inoculated intratesticularly. the guinea-pig was remarkably sensitive to n. asteroides, with an apparent relationship between pathogenicity and thermotolerance, confirming previous observations. mice were in general less suscepti ... | 1982 | 6760417 |
| effect of route on inoculation on host resistance to nocardia. | virulent strains of nocardia asteroides and nocardia caviae were injected into mice by five different routes. when these organisms were grown to the same stage of growth in the same medium and otherwise prepared identically, it was found that they differed significantly in their ability to infect and kill the host, depending entirely upon the route of inoculation. thus, n. caviae 112 was 30 times more virulent than n. asteroides guh-2 when administered intranasally, whereas n. asteroides was at ... | 1980 | 6991437 |
| comparative studies of antigen 21 in mycobacterium and nocardia species: possible taxonomic relationships with mycobacterium leprae. | studies of mycobacterium leprae, mycobacterium tuberculosis and nocardia caviae in comparison with each other and with other mycobacterium and nocardia species were performed on the basis of antigen 21 intramolecular heterogeneity. three different antisera were used: rabbit anti-mycobacterium smegmatis antiserum, rabbit anti-nocardia asteroides antiserum, and a lepromatous serum pool. with reference to each of the three antiserum sources used the strains were ranked in an order of relatedness or ... | 1980 | 7002798 |
| detection of antigen in nocardia caviae cross-reacting with mycobacterial antigen no. 21 in m. leprae using a lepromatous leprosy serum pool as antibody reagent. | eighteen strains of nocardia, representing five different species, were studied in crossed immunoelectrophoresis against a lepromatous leprosy serum pool for the presence of antigen no. 21. this mycobacterial antigen shows antigenic heterogeneity with species specific antigenic determinants defined in mycobacterium leprae. all four strains of n. caviae were found to share antigen no. 21 determinants with mucobacteria. all other strains of nocardia were negative in these direct immunoprecipitatio ... | 1980 | 7002810 |
| numerical classification of some named strains of nocardia asteroides and related isolates from soil. | one hundred and forty-nine strains of nocardiae, freshly isolated from soil samples obtained from a number of countries with either tropical or temperate climates, and from rubber pipe seals, were compared with appropriate marker cultures in a numerical phenetic study using 156 unit characters. marker strains were chosen to represent the nocardia asteroides complex, other nocardia species and related taxa in an effort both to classify the new soil isolates and, possibly, clarify the structure of ... | 1980 | 7003057 |
| recovery of microorganisms from synovial and pleural fluids of animals using hyperosmolar media. | l-phase (cwd) broth and plate media were used in parallel with conventional microbiological media during a 3-year period for culturing synovial and pleural fluids of animals. two kinds of recoveries were obtained where parallel conventional methods were negative: (1) parent or normal bacteria, in very low numbers; and (2) type b cwd variants in equally low numbers. organisms in group 1 were: streptococcus zooepidemicus from horses (2x); beta-hemolytic streptococci, lancefield gp. g (2x); staphyl ... | 1982 | 7101719 |
| brain abscess due to nocardia caviae. report of a fatal outcome associated with abnormal phagocyte function. | nocardia is an uncommon cause of human disease. we report a patient with a fatal brain abscess who had abnormal phagocyte function as measured by neutrophile chemotaxis, adherence, phagocytic function, and chemiluminescence in vitro and by rebuck skin window in vivo. antimicrobial agar dilution susceptibility suggested minocycline was more active than sulfamethoxazole. | 1982 | 7102599 |
| numerical and chemical classification of nocardia amarae. | twenty-one strains of nocardia amarae and marker cultures of mycobacterium, nocardia, rhodococcus and the 'aurantiaca' taxon were subjected to numerical phenetic analyses using 92 unit characters. the data were examined using the simple matching (ssm), jaccard (sj) and pattern (dp) coefficients and clustering was achieved using the unweighted average linkage algorithm. neither cluster nor aggregate cluster composition was markedly affected by the coefficient used or by test error, estimated at 1 ... | 1982 | 7119738 |
| structure of 2',3'-di-o-acyl-alpha-d-glucopyranosyl-(1 leads to 2)-d-glyceric acid, a new glycolipid from nocardia caviae. | the structure of a new glycolipid isolated from the acetone-soluble lipids of the strain of nocardia caviae has been determined. the water-soluble moiety contains one mole of d-glucose and one mole of d(-)-glyceric acid; the lipid moiety is a mixture of myristic, palmitic and stearic acids with small amounts of oleic acid. the structure of the deacylated compound was determined by periodate oxidation, methylation and enzymatic degradation. the localization of fatty acid residues at 2',3' on gluc ... | 1981 | 7285927 |
| role of l-forms of nocardia caviae in the development of chronic mycetomas in normal and immunodeficient murine models. | single-cell suspensions of nocardia caviae 112 were injected into normal, athymic, and asplenic mice by several different routes. the 50% lethal dose values, kill curve characteristics, histological and electron microscopic properties, organ clearance patterns, and induction of l-forms during the acute and chronic phase of disease were determined in groups of mice for up to 2 years after infection. from these data we concluded the following. (i) athymic and asplenic animals were significantly mo ... | 1981 | 7287189 |
| mycetoma due to nocardia caviae. the first israeli patient. | | 1980 | 7390691 |
| induction of l-phase variants of nocardia caviae within intact murine lungs. | the data presented show that cells of nocardia caviae 112 were converted to cell wall-deficient microbial variants within the intact murine lung after intranasal administration. at the time that these l-phase variants were recovered in large numbers from the lung, there was a correspondingly enhanced inflammation leading to alveolar consolidation and animal death. during the peak of this response (at 1 week after infection), normal nocardial cells were neither isolated from nor seen within the l ... | 1980 | 7399704 |
| a phylogenetic analysis of the genus nocardia with 16s rrna gene sequences. | partial sequences of the 16s rrna genes of the type strains of nine species of the genus nocardia were determined following the isolation and cloning of the amplified genes. these sequences were aligned with the sequences of representatives of the genera corynebacterium, gordona, mycobacterium, rhodococcus, and tsukamurella, and phylogenetic trees were inferred by using the fitch-margoliash and neighbor-joining methods. the genus nocardia formed a distinct clade that was most closely associated ... | 1995 | 7537058 |
| primary cutaneous nocardia otitidiscaviarum infection: case report and review. | organisms of the genus nocardia cause a variety of illnesses in humans and other mammals. nocardiae normally enter the body via the respiratory tract, but they may also be directly inoculated into the skin, causing primary cutaneous disease. nocardia otitidiscaviarum is one of the less commonly isolated species of nocardia, but it can produce localized or disseminated infection. we report a case of primary cutaneous n. otitidiscaviarum infection and review the clinical and microbiological featur ... | 1995 | 7620008 |
| primary lymphocutaneous nocardiosis due to nocardia otitidiscaviarum: the first case report from japan. | we report a case of lymphocutaneous syndrome caused by nocardia otitidiscaviarum (formerly known as n. caviae) in a 78-year-old woman who underwent long-term therapy with prednisolone for bronchial asthma. histological examination showed granulomatous reaction with multiple polymorphonuclear leukocytes and revealed a gram positive filament in the dermis. gram-positive, slightly acid-fast branched filaments were also found in the smear of the purulent material. the cell wall constituents of the i ... | 1995 | 7673554 |
| phosphorylative inactivation of rifampicin by nocardia otitidiscaviarum. | rifampicin was inactivated by nocardia otitidiscaviarum to yield two products designated rip-3 and rip-4. the full structures of rip-3 and rip-4 were determined to be 21-(o-phosphoryl) rifampicin and 3-formyl-21-(o-phosphoryl) rifamycin sv, respectively, but neither product had any antimicrobial activity. | 1994 | 7928806 |
| first reported nocardia otitidiscaviarum infection in an aids patient in italy. | nocardiosis is a well-described infection in immunocompromised patients, and has been rarely documented in patients with aids. nocardia asteroides is the most frequently isolated etiologic agent. rare cases are due to n. brasiliensis and n. otitidiscaviarum. this work describes the first case of nocardiosis in italy caused by n. otitidiscaviarum in an aids patient. a 31 year-old intravenous drug abuser with a diagnosis of full-blown aids, presented with high fever and lymphadenitis with a fistul ... | 1994 | 7935727 |
| lymphocutaneous nocardiosis caused by nocardia caviae: the first case report from asia. | | 1993 | 8408800 |
| primary cutaneous nocardiosis caused by nocardia otitidiscaviarum: two cases and a review of the literature. | we report two cases of primary cutaneous nocardiosis due to nocardia otitidiscaviarum. the first case is a mycetoma, the second, a cutaneous abcess: these two cases were imported into france (vietnam, zimbabwe). the literature on primary cutaneous nocardiosis due to n. otitidiscaviarum is reviewed. | 1995 | 8544221 |
| nocardia pseudobrasiliensis sp. nov., a new species of nocardia which groups bacterial strains previously identified as nocardia brasiliensis and associated with invasive diseases. | we studied five strains of a new nocardia taxon recently identified among nocardia brasiliensis strains associated with invasive diseases (r. j. wallace, jr., b. a. brown, z. blacklock, r. ulrich, k. jost, j. m. brown, m. m. mcneil, g. onyi, v. a. steingrube, and j. gibson, j. clin. microbiol. 33:1528-1533, 1995) to determine their taxonomic status. several characteristics of these organisms, including the presence of chemotype iv cell walls, nocardomycolic acids, a predominant menaquinone simil ... | 1996 | 8573505 |
| pneumonia caused by nocardia caviae in a healthy neonate. | | 1995 | 8714625 |
| mixed pulmonary infection with nocardia, candida, methicillin-resistant staphylococcus aureus, and group d streptococcus species. | a 67-year-old man on prednisolone and azathioprine for ulcerative colitis, developed severe pneumonia due to nocardia otitidis caviarum, methicillin-resistant staphylococcus aureus, a group d streptococcus and candida albicans. the patient responded well to aggressive antimicrobial therapy. | 1996 | 8944211 |
| molecular study of persistence of nocardia asteroides and nocardia otitidiscaviarum strains in patients with long-term nocardiosis. | three nocardia asteroides and five nocardia otitidiscaviarum isolates recovered from three patients with long-term nocardiosis were compared by random amplification of polymorphic dna fingerprinting, antibiotic susceptibility testing, and enzymatic characterization. results obtained with primer dku49 (p. palittapongarnpim, s. chomyc, a. fanning, and d. kunimoto, j. infect. dis. 167:975-978, 1993) provide evidence that patient a was infected by two n. asteroides strains during a single episode of ... | 1997 | 9114399 |
| rapid identification of clinically significant species and taxa of aerobic actinomycetes, including actinomadura, gordona, nocardia, rhodococcus, streptomyces, and tsukamurella isolates, by dna amplification and restriction endonuclease analysis. | a previously described pcr-restriction fragment length polymorphism (rflp) identification schema for nocardia that used an amplified 439-bp segment (amplicon) of the 65-kda heat shock protein gene was evaluated for potential use with isolates of all clinically significant aerobic actinomycetes. the study included 28 reference (american type culture collection) strains and 198 clinical isolates belonging to 20 taxonomic groups. of these 198 isolates, 188 could be differentiated by this pcr-rflp m ... | 1997 | 9157134 |
| nocardia otitidiscaviarum infection of a traumatic skin wound. | a case of primary nocardia otitidiscaviarum infection of a skin wound over an open fracture in a previously healthy adult who suffered multiple trauma in a car accident is reported. the organism was identified in cultures of pus specimens from the infected wound. the case demonstrated the difficulties of testing susceptibility of nocardiae in vitro and the necessity of prolonged antibiotic treatment. the prevalence of nocardial infections is underestimated, highlighting the need for adequate doc ... | 1997 | 9228480 |
| nocardia crassostreae sp. nov., the causal agent of nocardiosis in pacific oysters. | seven strains of bacteria were isolated from pacific oysters, crassostrea gigas, with a focal or systemic disease. the strains were aerobic, gram-positive, acid-fast, produced a mycelium which fragmented into irregular rod-like elements, had a peptidoglycan containing meso-diaminopimelic acid, arabinose and galactose as major sugars, mycolic acids with 46-58 carbon atoms and g + c-rich dna. all of these properties are consistent with the classification of the organisms in the genus nocardia. a p ... | 1998 | 9542093 |
| pulmonary nocardia otitidiscaviarum infection in a patient with chronic respiratory infection. | we report a case of pulmonary nocardia (n.) otitidiscaviarum infection in a 76-year-old man with chronic respiratory infection. the patient responded poorly to intravenous imipenem and oral minocycline, but later improved after treatment with trimethoprim-sulfamethoxazole. pulmonary infection with n. otitidiscaviarum should be considered in the differential diagnosis of chronic respiratory infections. further studies are needed to evaluate the correlation between species and drug susceptibility. | 1998 | 9840712 |
| nocardia uniformis nom. rev. | a soil isolate representing the putatively novel species 'nocardia uniformis' was found to have morphological, staining and chemotaxonomic properties consistent with its classification in the genus nocardia. an almost complete sequence of the 16s rdna of the strain was determined following cloning and sequencing of the amplified gene. the sequence was aligned with those available for nocardiae and phylogenetic trees were inferred using four tree-making algorithms. the organism was consistently a ... | 1999 | 10425784 |
| intracerebral abscess caused by nocardia otitidiscaviarum in a renal transplant patient--cured by evacuation plus antibiotic therapy. | we present a 50-year-old female who experienced generalized convulsion 3 months after a successful cadaveric renal transplantation. the first cerebral ct scan indicated cerebral frontal infarction. repeat ct some days later revealed progressive lesions, and a highly malignant tumor or abscess was suspected. antifungal and broad-spectrum antibacterial therapy was initiated. cerebral mri could not differentiate between these conditions, but a neutrophil granulocyte scan strongly suggested an infec ... | 2000 | 10971157 |
| primary brain abscess with nocardia otitidiscaviarum in an intravenous drug abuser. | a primary brain abscess with nocardia otitidiscaviarum in an intravenous drug abuser is reported. nocardia brain abscess has been reported infrequently and normally only in immunocompromised patients. the lungs are the most common primary focus, but brain abscess may also occur following direct cutaneous inoculation. in this case the clinical presentation was first diagnosed as an astrocytoma. however, n. otitidiscaviarum was isolated from the lesion after emergency craniotomy. in contrast to fi ... | 2001 | 11192495 |
| [pulmonary nocardia otitidiscaviarum infection in an immunocompetent host]. | a rare case of pulmonary nocardia otitidiscaviarum (n. otitidiscaviarum) was encountered in an immunocompetent host. a 74-year-old man was admitted to our hospital with a high fever and a productive cough. his chest radiograph and ct scan revealed infiltrative shadows in the right middle and lower lung fields. although several antibiotics (third-generation cephalosporin, minocycline, imipenem) were administered, the fever and cough persisted, and c-reactive protein remained elevated. repeated sp ... | 2000 | 11193319 |
| cutaneous nocardiosis of the chest wall and pleura--10-year consequences of a hand actinomycetoma. | we report an unusual case of primary cutaneous nocardiosis due to nocardia otitidiscaviarum presenting first as a mycetoma of the right hand and wrist. the patient refused treatment and was lost to follow-up until he showed up 10 years later with numerous discharging large sinuses and abscesses on the upper right quadrant of the chest wall and in the right armpit. roentgenograms revealed pleural masses. histology was in keeping with the diagnosis of mycetoma. treatment with amikacin, rifampicin ... | 2001 | 11306835 |
| [pulmonary nocardia otitidis-caviarum infection in a patient with cushing's disease]. | while nocardial infections are being diagnosed with increasing frequency, infection with nocardia otitidiscaviarum remains relatively uncommon. we report a case of pulmonary nocardia otitidis-caviarum infection in a 35-year-old man with cushing's disease. this work describes the first case of nocardiosis in japan caused by nocardia otitidis-caviarum in cushing's disease. the patient was admitted to our department because of edema. a diagnosis of cushing's disease was made on the basis of elevate ... | 2001 | 11431917 |
| pulmonary nocardiosis: clinical experience in ten cases. | pulmonary nocardiosis is an infrequent infection whose incidence seems to be increasing due to a higher degree of clinical suspicion and the increasing number of immunosuppressive factors. | 2001 | 11464085 |
| epidemiological aspects of mycetoma from a retrospective study of 264 cases in west bengal. | between 1981 and 2000, 264 cases of mycetoma were diagnosed clinically and microbiologically at calcutta school of tropical medicine. retrospective analysis of the records revealed that the ratio of actinomycetomas and eumycetomas was 197 : 67; the male to female ratio was 183 : 81. ninety-four cases occurred in the 1980s and 170 in 1990s, with significantly more infections of actinomadura spp. (p < 0.01) and fewer with nocardia caviae (p < 0.01) during the last decade. pricking was the most com ... | 2002 | 12225511 |
| nocardia otitidiscaviarum infection in a cat. | | 2002 | 12418540 |
| [pulmonary nocardia otitidis-caviarum infection in a patient with bronchiectasia]. | | 2002 | 12451664 |
| primary lymphocutaneous nocardiosis caused by nocardia otitidiscaviarum. | a case of primary lymphocutaneous nocardiosis caused by nocardia otitidiscaviarum in a 69-year-old previously healthy woman is described. the organism was identified in cultures of pus specimens. the patient was treated with a six-month course of oral trimethoprim-sulfamethoxazole chemotherapy following incision and drainage, and the infection completely resolved. | 2002 | 12596292 |
| [nocardia otitidiscaviarum, cutaneous infection in a patient receiving long-term corticosteroid treatment]. | a 62-year-old man, under long-term corticosteroid therapy for pigeon breeder's disease, was admitted to endocrinology disease department for cutaneous abscess on back, limbs and scalp. culture of various bacteriological samples (cutaneous abscess, blood culture) isolated nocardia otitidiscaviarum. the patient was treated by trimethoprime-sulfametoxazole during several weeks with abscess disappearance. our laboratory quickly identificatied a bacteria belonging to the nocardia genus, with simple t ... | 2003 | 12702479 |
| nocardia otitidiscaviarum: an unusual nocardia species causing a primary lymphocutaneous infectious process in a mildly immunosuppressed patient. | | 2002 | 14673241 |
| nocardia inohanensis sp. nov., nocardia yamanashiensis sp. nov. and nocardia niigatensis sp. nov., isolated from clinical specimens. | comparative 16s rdna studies on six strains of actinomycete isolated from clinical specimens revealed that they belong to the genus nocardia and are closely related to nocardia seriolae, nocardia otitidiscaviarum, nocardia uniformis, nocardia pseudobrasiliensis and nocardia crassostreae. however, the novel organisms consistently formed a clade distinct from that of the five latter species. determination of dna-dna relatedness indicated that these strains could be classified under three novel spe ... | 2004 | 15023976 |
| first report of pulmonary nocardia otitidiscaviarum infection in an immunocompetent patient from turkey. | nocardiosis is a rare disease, and worldwide, respiratory and disseminated infections are most often due to nocardia asteroides which is recognised increasingly as an opportunistic infection in patients with underlying chronic debilitating disease or immunodeficiency. however, infection with n. otitidiscaviarum and pulmonary nocardiosis in an immune-competent host remains very rare. we report a 65-year-old immune-competent male with pulmonary n. otitidiscaviarum infection in whom complete cure w ... | 2004 | 15055871 |
| nocardia otitidiscaviarum (gam-5) induces parkinsonian-like alterations in mouse. | parkinson's disease, a major neurodegenerative disorder in humans whose etiology is unknown, may be associated with some environmental factors. nocardia otitidiscaviarum (gam-5) isolated from a patient with an actinomycetoma produced signs similar to parkinson's disease following iv injection into nmri mice. nmri mice were infected intravenously with a non-lethal dose of 5 x 10(6) colony forming units of n. otitidiscaviarum (gam-5). fourteen days after bacterial infection, most of the 60 mice in ... | 2004 | 15064817 |
| brain abscess due to nocardia otitidiscaviarum: report of a case and review. | we present a case of brain abscess caused by nocardia otitidiscaviarum in an immunocompromized 44-y-old male. only 7 other cases of n. otitidiscaviarum brain abscess or involvement were found in the literature. the mortality was 75% despite treatment among cases reviewed. there is a lack of therapeutic guidelines regarding brain abscesses due to nocardia. | 2004 | 15287385 |
| pyothorax caused by nocardia otitidiscaviarum in a patient with rheumatoid vasculitis. | we report a case of pyothorax caused by nocardia (n.) otitidiscaviarum infection in a 69-year-old man with rheumatoid vasculitis, who was regularly treated with prednisolone in our hospital. initially, the patient responded poorly to intravenous imipenem/cilastatin (ipm/cs), minocyclin (mino), and oral trimethoprim-sulfamethoxazole (tmp-smx), but later improved after treatment with levofloxacin (lvfx) and gentamicin sulfate (gm) according to in vitro susceptibility tests. to our knowledge, this ... | 2004 | 15335193 |
| biotransformation of bile acids by pathogenic actinomycetes nocardia otitidiscaviarum and amycolatopsis sp. strains. | three sterol-type compounds (compounds 4, 5 and 6) were isolated from culture broth of pathogenic nocardia otitidiscaviarum ifm 0988 and amycolatopsis sp. ifm 0703 strains which were isolated from japanese patients. the structures of the compounds were determined by nmr and mass spectrometric analyses. the structural studies indicated that compound 4 is a biotransformation product from cholic acid derivative in a nutrient culture medium constituent by a reductase-type enzyme, and the remaining t ... | 2005 | 16060390 |
| nocardia concava sp. nov., isolated from japanese patients. | two actinomycete strains, ifm 0354(t) and ifm 0576, isolated from japanese patients, were found to have morphological, biochemical and chemotaxonomic properties consistent with their classification in the genus nocardia. the strains resembled nocardia otitidiscaviarum and nocardia uniformis in their phenotypic properties. comparative 16s rrna gene sequence analysis showed that the strains are closely related to nocardia seriolae. dna-dna relatedness values and phenotypic differences from n. seri ... | 2005 | 16166713 |
| primary cutaneous nocardia otitidiscaviarum infection in a patient with rheumatoid arthritis treated with infliximab. | anti-tumor necrosis factor-a (anti-tnf-a) therapy strategies result in significant clinical benefits in patients with rheumatoid arthritis, but with an increased rate of serious infectious diseases. we describe a patient receiving infliximab who developed a primary cutaneous nocardia otitidiscaviarum infection after a skin injury. | 2005 | 16331777 |
| [bacteremic infection due to nocardia otitidiscaviarum: case report and review]. | we present a case of bacteremic pneumonia caused by nocardia otitidiscaviarum in a corticodependent copd. blood and sputum cultures on mycobacterial media were positives and identification was done using 16s rdna sequencing. in this article we review the most relevant communications about nocardia spp infection and study the strain susceptibility using e-test. | 2005 | 16351482 |
| engineering a rare-cutting restriction enzyme: genetic screening and selection of noti variants. | restriction endonucleases (reases) with 8-base specificity are rare specimens in nature. noti from nocardia otitidis-caviarum (recognition sequence 5'-gcggccgc-3') has been cloned, thus allowing for mutagenesis and screening for enzymes with altered 8-base recognition and cleavage activity. variants possessing altered specificity have been isolated by the application of two genetic methods. in step 1, variant e156k was isolated by its ability to induce dna-damage in an indicator strain expressin ... | 2006 | 16456032 |
| isolation of nocardia caviae from soil and its pathogenicity for laboratory animals. | | 1965 | 16562088 |
| clinical and microbiological features of nocardiosis 1997-2003. | nocardiosis has been believed to be caused by the members of the nocardia asteroides complex and the nocardia brasiliensis species. however, recent advances in genotypic identification have shown that the genus exhibits considerable taxonomic complexity and the phenotypic markers used in the past for its identification can be ambiguous. the aim of this study was to assess the species distribution of nocardia isolates and to determine whether there are differences in pathogenicity or antimicrobia ... | 2007 | 17374898 |
| disseminated nocardia otitidiscaviarum infection in a woman with sickle cell anemia and end-stage renal disease. | nocardia otitidiscaviarum is an uncommon human pathogen and a rare cause of pulmonary infection and bacteremia. we report a case of n. otitidiscaviarum bacteremia and pulmonary infection in a patient with end-stage renal disease (chronic kidney disease, stage 5) and sickle cell anemia. the epidemiology, pathogenesis, and treatment of nocardia infections are discussed. | 2007 | 17570990 |
| [postoperative nocardiosis caused by nocardia otitidiscaviarum: pitfalls and delayed diagnosis]. | nocardiosis is an uncommon infection, which is exceptionally present as a postoperative event. a case of postoperative pulmonary and cerebro-meningeal infection caused by nocardia otitidiscaviarum after a leg amputation in a diabetic patient is reported. diagnosis has been delayed and the clinical, radiological and microbiological causes of this delay are assessed from a quality of care management point of view. recommendations are proposed regarding physicians' role and optimized microbiologica ... | 2007 | 17572044 |
| nocardia otitidiscaviarum: cause of long-term cutaneous abscesses on the leg of an immunocompetent man. | | 2007 | 17709682 |
| hydrocarbon degradation by thermophilic nocardia otitidiscaviarum strain tsh1: physiological aspects. | indigenous thermophilic hydrocarbon degraders are of special significance for the bioremediation of oil-contaminated desert soils with ambient temperature of 45-50 degrees c. the first objective of this study was to demonstrate the hydrocarbon-degrading capability of nocardia otitidiscaviarum tsh1 (dsm 45,036) which grows optimally at 50 degrees c. analysis of the metabolic profile of the strain tsh1 showed that it could metabolize phenol, intermediate-chain-length n -alkanes and some polycyclic ... | 2007 | 18072240 |
| degradation of phenanthrene and anthracene by nocardia otitidiscaviarum strain tsh1, a moderately thermophilic bacterium. | the metabolism of phenanthrene and anthracene by a moderate thermophilic nocardia otitidiscaviarum strain tsh1 was examined. | 2008 | 18312570 |
| naphthalene metabolism in nocardia otitidiscaviarum strain tsh1, a moderately thermophilic microorganism. | the thermophilic bacterium nocardia otitidiscaviarum strain tsh1, originally isolated in our laboratory from a petroindustrial wastewater contaminated soil in iran, grows at 50 degrees c on a broad range of hydrocarbons. transformation of naphthalene by strain tsh1 which is able to use this two ring-polycyclic aromatic hydrocarbon (pah) as a sole source of carbon and energy was investigated. the metabolic pathway was elucidated by identifying metabolites, biotransformation studies and monitoring ... | 2008 | 18471862 |
| nocardiosis: an overview and additional report of 28 cases in cattle and dogs. | phenotypic characteristics, antimicrobial susceptibility profile, and clinical-epidemiological features of 28 nocardia strains isolated from 19 cases of bovine mastitis, eight cutaneous-subcutaneous lesions and one case of pneumonia in dogs were evaluated. microbiological, biochemical, cytological and scanning electron microscopy methods were used in diagnosis. nocardia asteroides type iv, nocardia otitidiscaviarum,nocardia nova (type iii) and nocardia farcinica (type v) were isolated from bovin ... | 2008 | 18516465 |
| nocardia otitidiscaviarum pneumonia in an alpine chamois (rupicapra rupicapra rupicapra). | nocardia otitidiscaviarum was cultured from the lung of an alpine chamois (rupicapra rupicapra rupicapra) with suppurative bronchopneumonia. this is the first report of both nocardiosis and nocardia otitidiscaviarum in this wild ungulate species. | 2009 | 19361807 |
| a fatal case of nocardia otitidiscaviarum pulmonary infection and brain abscess: taxonomic characterization by molecular techniques. | we report on a rare case of pulmonary nocardiosis and brain abscess caused by nocardia otitidiscaviarum in an elderly woman with chronic obstructive pulmonary disease. taxonomic identification involved phenotypic testing, restriction fragment length polymorphism (rflp), and complete 16s rrna gene sequencing. | 2009 | 19366439 |
| comparative in vitro activities of nemonoxacin, doripenem, tigecycline and 16 other antimicrobials against nocardia brasiliensis, nocardia asteroides and unusual nocardia species. | the aim of this study was to assess the in vitro activities of nemonoxacin (a novel non-fluorinated quinolone), doripenem, tigecycline and 16 other antimicrobial agents against the nocardia species. | 2009 | 19398458 |
| pulmonary nocardiosis from a tertiary care hospital in southern india. | the present study highlights eight cases of pulmonary nocardiosis diagnosed during the time period of january 2006-march 2008. nocardia otitidiscaviarum, n. asteroides and n. brasiliensis were isolated from these cases. whereas six patients were treated successfully, one showed partial response and one case expired before the institution of treatment. early and correct microbiological diagnosis can help to decrease the disease-related morbidity and mortality. | 2009 | 19535755 |