| current status of treatment of pneumonia. | proper treatment of pneumonia is dependent upon a correct diagnosis. pneumonia may be due to infectious agents, allergic phenomena, or chemical causes. treatment regimens are outlined for the various types of pneumonia--pneumococcal, staphylococcal, fungal, and pneumonia due to gram-negative and anaerobic gram-negative bacilli, to blastomyces dermatitidis, and to the parasite pneumocystis carinii. in discussing current concepts of treatment, several well-known methods are emphasized, as well as ... | 1975 | 792 |
| multiple forms of cyclohexanone oxygenase from nocardia globerula cl1. | the cyclohexanone 1,2-monooxygenase of nocardia globerula cl1 exists as two electrophoretically distinct forms. these are present in crude cell extracts and are not artifacts of enzyme purification or electrophoresis. they have been separated in mg amounts by preparative polyacrylamide gel electrophoresis and shown to have essentially identical kinetic, spectral and physical characteristics. they do differ in ph-activity profile and temperature stability. whether or not they are conformational i ... | 1976 | 4312 |
| purification and properties of an unusual nitrilase from nocardia n.c.i.b. 11216. | | 1976 | 12045 |
| dynamics of pyridine nucleotide coenzymes in nocardia cells. | | 1977 | 14180 |
| change in the composition and properties of humic acids under the action of microorganisms of the genus nocardia. | | 1978 | 25290 |
| screening for ph-dependent alpha-l-arabinofuranosidases in various representative strains of actinomycetales. | | 1978 | 27906 |
| growth of nocardia rhodochrous on acetylene gas. | soil sediment enrichment cultures yielded a coryneform bacterium capable of growing in a mineral salts solution with acetylene gas as its only source of carbon and energy. based on morphological and physiological traits as well as on cell wall analysis, the bacterium was characterized as a strain of nocardia rhodochrous. maximal growth rates (generation time 2.7 to 3.0 h) on acetylene were obtained at 5 to 20% acetylene, 25 to 40% oxygen, ph 7.0 and 26 to 28 degrees c. yields (grams of dry cells ... | 1979 | 37235 |
| rabbit b spleen lymphocytes and t helper cells. i. responsiveness to mitogens of b cell subpopulations of different sedimentation velocities and subpopulations bearing or lacking fcgamma receptors. | the response to anti-allotype (anti-ab4), nocardia water soluble mitogen (nwsm), pneumococcal polysaccharide type iii (sss iii), and human fc fragments of various purified and unfractionated rabbit spleen cell populations was determined in terms of 3h-thymidine up-take. b cells were isolated either from untreated suspensions of spleen cells or from suspensions from which adherent and phagocytic cells were removed. the purification factor was greater than the enhancement of 3h-thymidine uptake by ... | 1979 | 39964 |
| [interferon induced in the hamster by subunits of "nocardia": essay of protection against rabies (author's transl)]. | lipid-free cells of nocardia opaca and a cell extract (nwsm) are interferon inducers in syrian hamsters: peak interferon appears 2 h after injection as compared to 8 h in the case of interferon induced by inactivated ndv virus. the interferon induced by nocardia product is inactivated by a treatment for 30 min at 56 degrees c or 24 h at ph 2: ndv-induced interferon is more stable under these conditions. hamsters inoculated with nwsm before and after infection with rabies virus are partially prot ... | 1979 | 43690 |
| [steroid-transforming enzymes from microorganisms. xi. reversibility of the dehydrogenation reaction of the steroid-1-dehydrogenase from nocardia opaca]. | highly purified preparations of the 4-en-3-oxosteroid: (acceptor)-1-en-oxidoreductase from nocardia opaca have been investigated in both types of reactions: 1.2-dehydrogenation of the 4-en-3-oxo-derivative and 1.2-hydrogenation of the 1.4-dien-3-oxo-derivative. it was not possible to separate the hydrogenating activity from the dehydrogenating activity by affinity chromatography, disc electrophoresis, sds-electrophoresis, and isoelectric focusing techniques. the pure enzyme preparation is discus ... | 1979 | 44773 |
| the effect of fixation procedures on the electron density of polysaccharide granules in nocardia corallina. | | 1975 | 51094 |
| superoxide dismutase from mycobacterium species, strain takeo. | superoxide dismutase from mycobacterium species, strain takeo, has been purified to homogeneity as judged by disc gel electrophoresis and ultracentrifugation. the enzyme was found to have a molecular weight of approximately 61 500 by sedimentation equilibrium and to contain manganese by atomic absorption and electron spin resonance spectra. the amino acid composition was also determined. the enzyme was considerably stable to the treatment with sodium dodecyl sulfate; unless incubating at 80 degr ... | 1976 | 58647 |
| catechol 1,2-dioxygenase from acinetobacter calcoaceticus: purification and properties. | procedures for the purification of catechol 1,2-dioxygenase from extracts of acinetobacter calcoaceticus strain adp-96 are described. the purified enzyme was homogeneous as judged by ultracentrifugation and acrylamide gel electrophoresis. the enzyme contained 2 g-atoms of iron per mol of protein. the enzyme had a broad substrate specificity and catalyzed the oxidation of catechol, 4-methylcatechol, 3-methylcatechol, and 3-isopropyl catechol. the activity of the enzyme was inhibited by heavy meta ... | 1976 | 58860 |
| bacterial cis-dihydrodiol dehydrogenases: comparison of physicochemical and immunological protperties. | cells of pseudomonas putida np, pseudomonas species (ncib 9816), and a nocardia species, after growth on naphthalene as sole source of carbon and energy, contain a nicotinamide adenine dinucleotide (nad+)-dependent enzyme that oxidizes cis-dihydrodiols of mono- and polycyclic aromatic compounds. similarly, cells of a strain of p. putida biotype a, when grown either on toluene or benzene vapors, were found to contain a dehydrogenase that oxidized dihydrodiols of aromatic hydrocarbons with cis ste ... | 1976 | 62750 |
| 57co-bleomycin for brain scan diagnosis of intracranial lesions. | | 1977 | 75263 |
| induction of interferon synthesis in mice by fractions from nocardia. | three fractions of nocardia, nocardia water-soluble mitogen (nwsm), nocardia water-soluble mitogen pellet (nwsmp), and the cell wall peptidoglycan, which are mitogenic for b lymphocytes, were able to induce circulating interferon in mice, nwsmp and nwsm being the most active. the peak of interferon appeared about 2 h after injection. the interferon induced by nswmp and nwsm was acid stable and antigenically related to viral interferon, as shown by neutralization with antibodies directed against ... | 1978 | 75845 |
| the metabolism of 1-phenylethanol and acetophenone by nocardia t5 and an arthrobacter species. | | 1978 | 77775 |
| the use of fluorescent and special staining techniques in the aspiration of nocardiosis and actinomycosis. | this report outlines the techniques and illustrates the utility of special stains and fluorescent microscopy when applied to aspiration cytology material. this procedure allowed quick and accurate diagnosis of opportunistic infectious organisms, specifically nocardiosis and actinomycosis. | 1978 | 83771 |
| evaluation of mycobacteriology laboratories: the acid-fast smear. | in a proficiency testing program, slides bearing acid-fast bacilli were sent to laboratories in new york state. the most reliable results were obtained in laboratories using the ziehl-neelsen method. cold staining procedures were less reliable. the auramine-rhodamine fluorescent stain, which produced many false positives, should be confirmed by the ziehl-neelsen procedure. the testing program described can be used to determine whether laboratories perform the acid-fast stain effectively. | 1978 | 84804 |
| polyphosphate- and atp-glucose phosphotransferase activities of nocardia minima. | | 1979 | 89794 |
| immunological cross-reactivity of pathogenic nocardia and related organisms. | | 1979 | 94563 |
| mycetoma caused by nocardia asteroides. | during the last 5 years six cases of mycetoma have been referred to the razi hospital, thehran. nocardia asteroides was found to be the causative agent in one case only. five of the patients were males, all being rice farmers, and one was a female. all of them belonged to northern iran which has a mediterranean climate. treatment of the condition still remains unsatisfactory and ineffective and amputation may have to be performed as a last resort. | 1978 | 97414 |
| microbial degradation of [c14c]polystyrene and 1,3-diphenylbutane. | microbial degradation of [beta-14c]polystyrene and 1,3-diphenylbutane, a compound structurally representing the smallest repeating unit of styrene (dimer), was investigated in soil and liquid enrichment cultures. degradation rates in soil, as determined by 14co2 evolution from applied [14c]polystyrene, varied from 1.5 to 3.0% for a 4-month period. although relatively low, these percentages were 15 to 30 times greater than values previously reported. enrichment cultures, containing 1,3-diphenylbu ... | 1978 | 98222 |
| antitumor activity of squalene-treated cell-wall skeleton of nocardia rubra in mice. | | 1978 | 103768 |
| immunological method to differentiate between antigens of tubercle bacilli, other mycobacterial species, and non-acid-fast bacteria. | sera from rabbits immunized with sonicates of mycobacterium bovis bcg were passed through an immunoadsorbent made of a soluble bcg extract to make partially purified antibodies to bcg. these antibodies were in turn used to prepare an immunoadsorbent through which the bcg extract was passed. the partially purified antigenic material was radiolabeled and subjected to electrophoresis in acrylamide gels. one of the radiolabeled fractions isolated (bcg-c) was found to bind to antibodies to bcg and h3 ... | 1978 | 103823 |
| cross-reactions between mycobacteria. ii. crossed immunoelectrophoretic analysis of soluble antigens of bcg and comparison with other mycobacteria. | cross-reactions between mycobacterium bovis bcg and various other mycobacteria, nocardia asteroides, corynebacterium pyogenes and listeria monocytogenes were studied by incorporating antibodies against these bacteria in the intermediate gel of a crossed immunoelectrophoretic system with bcg antigen and anti-bcg antibodies. in the bcg reference system forty-four distinct antigenic components were recorded, of which thiryt-three cross-reacted with mycobacterium tuberculosis, twenty-five with m. av ... | 1979 | 106465 |
| [enzymes of intermediary metabolism in coryneform bacteria]. | enzymes of the intermediate metabolism were studied in ten strains of corynebacterium-like organisms belonging to the genera arthrobacter, brevibacterium, corynebacterium and nocardia. all of these were found to contain enzymes of the glycolytic pathway, and nine strains among ten had dehydrogenases of the pentose phosphate shunt. the activity of enzymes of the citric acid cycle was low: alpha-ketoglutarate dehydrogenase was not found in arthrobacter, corynebacterium, brevibacterium linens and n ... | 1979 | 108525 |
| immunodiffusion studies of ribosomes in classification of mycobacteria and related taxa. | ribosomal preparations consisting of crude ribosomes (cr), 30s subunits (30s) and 16s core particles (16s) from four strains of the species mycobacterium bovis (bcg), mycobacterium fortuitum, mycobacterium phlei and mycobacterium smegmatis were analyzed by immunodiffusion technique for taxonomical purposes. the ribosomal preparations tested contained several interspecies cross-reacting precipitinogens. the number of precipitinogens demonstrated at the homologous reactions was generally larger th ... | 1979 | 109401 |
| microbiological transformations of nabilone, a synthetic cannabinoid. | a screening program was conducted to find microorganisms that modify the synthetic cannabinoid nabilone. after purification, the products from three cultures were analyzed by spectral methods to determine their chemical structures. an optically active 9s-hydroxy-6ar,10ar-trans cannabinoid was isolated from a culture of an unidentified soil bacterium designated a24007. from bacillus cereus cultures were isolated a 9s,6'-dihydroxy-6ar,10ar-trans cannabinoid, a 9s-hydroxy-6'-keto-6ar,10ar-trans can ... | 1979 | 114111 |
| microimmunodiffusion test for nocardiosis. | sera from 71 patients with culturally proven nocardiosis were tested for precipitins against a pool of nocardia asteroides and n. brasiliensis culture filtrates and against antigens from the supernatant of homogenized n. asteroides cells. a human nocardiosis case serum was used as a reference. sera from 56 of the 71 cases were reactive with either the culture filtrate antigen, the homogenate antigen, or both antigens, resulting in an overall sensitivity of 79%. sera from 35 of the patients (49%) ... | 1979 | 114533 |
| [growth of nocardio- and coryneform bacteria on media with low molecular weight alcohols]. | | 1979 | 119140 |
| [carboxylation enzymes of coryneform bacteria]. | the enzymes of carbon dioxide heterotrophic fixation were studied in six strains of coryneform bacteria belonging to the genera arthrobacter, brevibacterium, corynebacterium and nocardia. all of the strains were found to contain pep (phosphoenolpyruvate) carboxylase (ec 4.1.1.31), nadp or nad dependent malic enzymes (ec 1.1.1.38--40). pyruvate carboxylase (ec 6.4.1.1) was found only in three strains of coryneforms: brevibacterium ammoniagenes, corynebacterium aquaticum and nocardia erythropolis. ... | 1979 | 119147 |
| in vivo activation of murine peritoneal macrophages by nocardia water soluble mitogen (nwsm). | in vitro nwsm has been shown to be a b cell mitogen and a polyclonal activator. although nwsm has been also shown to be adjuvant active in vivo, motogenicity and polyclonal activation are not observed when this fraction has been administered to mice. in contrast, the experiments reported here demonstrate that after in vivo administration several effects of nwsm on mouse peritoneal macrophages can be observed: nwsm was able to induce an important increase in the ability of peritoneal macrophages ... | 1979 | 121200 |
| [plea for medical mycology, "step-child" of our doctrine and research]. | | 1975 | 125248 |
| drug eruption associated with sulfonamide treatment of vertebral osteomyelitis in a dog. | drug eruption was diagnosed in a 4-year-old german shepherd dog being treated with sulfonamides for vertebral osteomyelitis due to infection with nocardia spp. the eruption was characterized by generalized, pruritic, eczematous dermatitis. diagnosis was based on a history of repeated exposure to sulfonamides, skin biopsy findingd, and clinical recovery on cessation of sulfonamide therapy. | 1976 | 132414 |
| [nocardie and their problems (author's transl)]. | | 1977 | 145910 |
| [isolation of actinomadura from soils on selective media with kanamycin and rifampicin]. | | 1978 | 146454 |
| [new species of the genus nocardia and its antibiotic properties]. | a culture of a new species of nocardia, i.e. n. indigoensis producing an antibiotic close to celicomycins was isolated from a soil sample of kazakhstan plated on the selective medium with kanamycin. by a number of chemical properties and biological activity the antibiotic differed from celicomycins. probably it is a new natural substance. | 1978 | 147645 |
| microbial conversion of ethylbenzene to 1-phenethanol and acetophenone by nocardia tartaricans atcc 31190. | a culture of nocardia tartaricans atcc 31190 was capable of catalyzing the conversion of ethylbenzene to 1-phenethanol and acetophenone while growing in a shake flask culture with hexadecane as the source of carbon and energy. this subterminal oxidative reaction with ethylbenzene appears not to have been previously reported for nocardia species. when n. tartaricans was grown on glucose as its source of carbon and energy and ethylbenzene was added, no subsequent production of 1-phenethanol or ace ... | 1979 | 93878 |
| [bioconversion of steroids in mutants of nocardia restrictus]. | nocardia restrictus grows quickly on synthetic media containing different carbonated substrates (steroids, organic acids). the control of growth parameters of this microbial species allowed the development of the production and selection methodology for mutants unable to grow on androst-4ène-3,17-dione. a stable mutant convert androst-4-ène-3,17-dione in perhydroindan propionic acid without addition of any degradation inhibitor in the medium. | 1978 | 153186 |
| cellular basis of regulation of expression of idiotype. ii. immunity to anti-mopc-460 idiotype antibodies increases the level of anti-trinitrophenyl antibodies bearing 460 idiotypes. | the antibody response of balb/c mice to trinitrophenyl (tnp)-levan or tnp-nocardia water-soluble mitogen (nwsm) includes a small but significant fraction of antibodies which share idiotypes (id) with the dinitrophenyl (dnp)- and tnp-binding myeloma protein mopc-460. active immunization of balb/c mice with mopc-460 or passive administration of anti-460-id antibodies suppresses the 460-id+ component of the anti-tnp response. by contrast, active immunization of balb/c with anti-460-id antibodies or ... | 1979 | 85684 |
| opportunistic infection in children. iii. in the normal host. | | 1975 | 171360 |
| production of 13beta-alkyl-3-methoxy-8,14-seco-1,3,5(10),9(11)-gonatetraen-14beta-ol-17-ones and 13beta-alkyl-3-methoxy-8,14-seco-1,3,5(10),9(11)-gonatetraen-17alpha-ol-14-ones by microbial enzymes. | for the purpose of producing hydroxy-keto-seco-steroids in which hydroxyl group is attached to a carbon atom having the r-configuration, numerous biochemically active microorganisms were tested without any success. the hydroxysteroid oxidoreductase enzymes of the investigated bacterial, yeast and fungal strains were suitable only for the production of 17beta-ol-14-one and 14alpha-ol-17-one derivatives. the required compounds were prepared by combinations of enzymatic reactions with chemical redu ... | 1975 | 179287 |
| bacterial decomposition of synthetic 14c-labeled lignin and lignin monomer derivatives. | nocardia sp. which was isolated from soil is capable of degrading synthetic lignin and utilizing its monomer derivatives. decomposition was monitored by measuring the 14co2 evolved and o2 consumed, when the bacterium was grown on a medium containing specifically 14c-labeled ligning or monomer phenolic compounds as major carbon source. the time course of the 14co2 release and o2 uptake indicates a significant depolymerization and utilization of lignin by the nocardia sp. | 1978 | 80922 |
| the adjuvant effect of microbial products on the immune response. | | 1976 | 185941 |
| the fifth a.j. kluyver memorial lecture delivered before the netherlands society for microbiology on october 9th, 1975, at the delft university of technology, delft. the physiology of hydrogen bacteria. | | 1976 | 185955 |
| the mannophosphoinositides of nocardia asteroides. | the phospholipid of n. asteroides has been investigated. it was found to contain phosphatidyl ethanolamine, cardiolipin, phosphatidyl inositol and a family of mannophosphoinositides. dimannophosphoinositides with 3 and 4 moles of fatty acid per phosphate residue represented the major glycophospholipids besides small amounts of other more glycosylated mannophosphoinositides. | 1976 | 186296 |
| immunochemical relatedness among ribosomes of mycobacteria, nocardia and corynebacteria [proceedings]. | | 1978 | 80189 |
| a comparative study of the 'rhodochrous' complex and related taxa by delayed-type skin reactions on guinea pigs and by polyacrylamide gel electrophoresis. | cell extracts prepared by ultrasonic disruption of 17 strains of the 'rhodochrous' complex and related taxa were compared by polyacrylamide gel electrophoresis and for immunologic relatedness, by skin test reactions. two organisms, jensenia canicruria and nocardia calcarea, gave similar gel patterns and skin test reactions, and are considered to be identical. extracts of nocardia rubra showed a strong antigenic relationship with those of three nocardia pellegrino organisms (n325, n324 and n420) ... | 1977 | 70505 |
| the complementary role of computerized axial transmission tomography and radionuclide imaging of the brain. | computerized axial transmission tomography and radionuclide imaging are complementary procedures, and the following recommendations are made as to their use. where there is no real clinical suspicion of intracranial disease, either modality can be used for "rule out" screening; the choice can frequently be made on the basis of which modality is cheaper or more quickly available. it should be remembered that "quicker" is often "cheaper". total cost is determined, not only by the cost of the proce ... | 1977 | 193193 |
| mannitol oxidation in two micromonospora isolates and in representative species of other actinomycetes. | mannitol kinase and mannitol-1-phosphate dehydrogenase activities were detected in two micromonospora isolates. the presence of these enzyme activities indicates that mannitol is catabolized first to mannitol-1-phosphate and then to fructose-6-phosphate. mannitol-oxidizing enzymes were also surveyed in representative species of four other genera of actinomycetes. mannitol-1-phosphate dehydrogenase was detected in cell-free extracts of streptomyces lactamdurans. in contrast, cell-free extracts of ... | 1977 | 194534 |
| [erythrasma of the nails]. | we have studied 17 cases of pseudomycotic onychoses. this condition is frequently seen in the toe nails with the clinical aspect of hyperkeratosis of the nail bed and onycholysis. the giemsa stained preparations have been performed with the clinical material previously heated in a 40% ohk solution and washed out with distilled water by centrifugation. the microorganism has similar or identical characteristics to those of the agent of erythrasma of the folds. its morphology and physiological char ... | 1976 | 65505 |
| [fluctuations in the level of cyclic amp and activities of adenylate cyclase and cyclic-amp phosphodiesterase in synchronous cultures of the prokaryote nocardia restricta (author's transl)]. | | 1978 | 207351 |
| antigenicity of mannophosphoinositides of nocardia. | | 1978 | 210124 |
| [cancer immunotherapy with bcg cell-wall skeleton (author's transl)]. | | 1978 | 211546 |
| periodic cyclic amp uptake by synchronously grown cells of nocardia restricta and arthrobacter globiformis. | | 1978 | 212312 |
| effect of cyclic nucleotides, isoproterenol and cholera toxin on dna synthesis triggered by mitogens. | the effect of cyclic nucleotides, isoproterenol and cholera toxin on phytohaemagglutinin (pha), concanavalin a (con a) and anti-allotype-induced rabbit lymphoid cell proliferation was examined. cholera toxin in concentrations ranging from 10(-8) microgram to 1 microgram per culture inhibited dna synthesis, triggered by pha, con a and nocardia water-soluble mitogen (nwsm). it had the opposite effect on stimulation with antibodies directed against allotypic specificities of the immunoglobulin ligh ... | 1978 | 212823 |
| studies on the biodegradation of nonionic surfactants applied in the polyester fiber industry. i. activated sludge bacteria degrading the surfactants. | the paper presents characteristics of 76 strains of bacteria capable of utilizing nonionic surfactants cirrasol fp, cirrasol sf 200 and cirrasol tcs as the source of carbon. the strains were isolated from two activated sludges adapted to the purification of wastes containing the above compounds at concentration 150--200 mg/l. the isolated strains belonged to the genera: achromobacter, alcaligenes, arthrobacter, flavobacterium, mycobacterium, nocardia, pseudomonas and xanthomonas. with load 0.11 ... | 1976 | 62497 |
| the effects of mitogens on the expression of epstein-barr virus antigens in human lymphoid cell lines. | treatment of human lymphoblastoid cells with either phytohemagglutinin (pha), concanavalin a, staphylococcus protein a, or polyinosinic acid-polycytidylic acid, in combination with 5-iodo-2' deoxyuridine (iudr) markedly increased the expression of epstein-barr virus (ebv) early antigen (ea) relative to iudr alone. such treatment did not, however, modify the production of virus capsid antigen in any of the lymphoid cell lines tested. the effect of pha on ea induction in raji cells was not accompa ... | 1979 | 221589 |
| [morphological tinctorial and biochemical properties of mycobacteria and nocardia]. | | 1976 | 57615 |
| the adaptation of fluorescence microscopy for nocardia asteroides: a preliminary report. | the fluorescence microscope is extremely effective in revealing the presence and morphology of nocardia asteroides. this has been effectively demonstrated when the auramine fluorochrome was decolourized with 1% h2so4 and the interval of decolourization was limited to two minutes and thirty seconds. when nocardia asteroids was seeded in sputum found to be negative for acid-fast organisms and in greatly diluted quantities after one hour intervals, its presence was still revealed with the flouresce ... | 1975 | 53968 |
| cytostatic activity of peripheral blood monocytes against bronchogenic carcinoma cells in patients with lung cancer. | cytostatic acitivity of peripheral blood monocytes against cultured cell lines of bronchogenic carcinoma was examined in patients with lung cancer. cytostatic activity in lung cancer patients with neither augmented nor suppressed as compared with that of controls such as normal healthy persons, patients with malignancies other than lung cancer, and patients with benign respiratory diseases. there was no correlation between the cytostatic activity of monocytes and the advance of clinical stages o ... | 1979 | 229054 |
| [steroid-transforming enzymes from microorganisms. ix. affinity chromatographic preparation and studies of the apoenzyme from a 4-en-3-oxosteroid: (acceptor)-1-en-oxidoreductase from nocardia opaca]. | from the flavoenzyme, 4-en-3-oxosteroid: (acceptor)-1-en-oxidoreductase of nocardia opaca, prosthetic group and apoenzyme were separated quantitatively by means of affinity chromatography in the presence of 2 m (nh4)2 at ph 3.0. subsequently the apoenzyme was eluted from affinity matrix by 0.01 m phosphate buffer, ph 8.0, whereas under these conditions the intact enzyme could not be eluted. the whole enzyme activity applied could be restored by incubation of the eluted apoenzyme with fad. the bi ... | 1979 | 44397 |
| volume, adherence properties, membrane antigens and mitogen responsiveness of rabbit lymphoid cell subpopulations. | subpopulations of rabbit spleen cells which respond to t and b mitogens, respectively, can be distinguished by sedimentation velocity in the earth's gravitational field. t cell subpopulations which differed in their responsiveness to con a and to pha could be identified by differences in adherence properties and by their sensitivity to complement mediated cell kill with rtla-antiserum. | 1975 | 234909 |
| penicillin acylase (bacterial). | | 1975 | 237220 |
| [distribution of pyrimidine blocks in the dna of brevibacterium linens, arthrobacter globiformis, nocardia corallina and nocardia rubra]. | the nucleotide composition and the frequency of pyrimidine blocks were studied in dna of the following bacteria: brevibacterium linens (weignamm, 1910) breed, 1953; arthrobacter globiformis (conn, 1928) conn et dimmick, 1947; nocardia corallina (bergey et al., 1923) waksman et henrici, 1948; nocardia rubra (krassilnikov, 1949) waksman et henrici, 1948. these organisms are classed by some microbiologists as mycobacteria (the mycobacteriaceae family) while other authors regard them as representati ... | 1975 | 241002 |
| changes in the composition and properties of humic acids brought about by the action of microorganisms of the genus nocardia. | the results of an investigation of the influence of microorgansims of the genus nocardia on changes in the composition and properties of humic acids are presented. according to these data, the elemental composition and ir spectra showed different effects on the structure of humic acids after utilization of these compounds as a nutrient source for three and six months by microorganisms. | 1978 | 33724 |
| pulmonary nocardiosis associated with primary nocardial infection of the oral cavity. | a case of pulmonary nocardiosis associated with primary nocardial infection of the oral cavity in a compromised host is presented. nocardia asteroides, an aerobic, gram-positive, branching, filamentous fungus, was demonstrated in the sputum and in pathologic specimens from gingival sulci stained by gram's method and the acid-fast method kinyoun. the organism was identified in cultures made on sabouraud's glucose agar. marked clinical improvement was noted when the patient received high dosage of ... | 1978 | 272602 |
| [case of nocardiasis of the submaxillary region and neck]. | | 1979 | 290068 |
| origin of adifferentiated variants of streptomyces roseoflavus in submerged culture. | adifferentiated nocardia-like variants (nv) of streptomyces roseoflavus var. roseofungini, similar in their cultural characteristics with the variant 1-68 described elsewhere (nikitina, 1968; kalakoutskii a. nikitina, 1976), can be obtained not only in the course of growth of the parent culture on a solid medium containing fructose in the form of secondary colonies, but also during submerged cultivation with stirring. interruptions in aeration do not affect accumulation of the cells of such vari ... | 1978 | 26856 |
| human b cell differentiation. i. immunoglobulin synthesis induced by nocardia mitogen. | nocardia water-soluble mitogen (nwsm) is a mitogen which activates human b lymphocytes even in the absence of t cells. tonsil and peripheral blood lymphocytes cultured in the presence of nwsm gave rise to large numbers of cells containing cytoplasmic immunoglobulins of igm, iga or igg classes. the number of plasma cells appeared to be elevated as early as day 3 of culture and peaked on day 5 or 7. the igm response preceded the development of cells containing other ig classes, and was found to re ... | 1978 | 306922 |
| mitogenic analysis of murine b-cell heterogeneity. | the b-cell mitogens lipopolysaccharide (lps), nocardia water-soluble mitogen (nwsm), and dextran sulfate (dxs) react with different subpopulations of b lymphocytes. selective in vitro killing of cells responding to either lps or nwsm has little effect on the in vitro response to the other mitogen, although the response to dxs is reduced in both cases. if, after selective in vitro killing, cells are injected into irradiated mice for 2-3 wk before measuring their in vitro mitogen responses, the sa ... | 1978 | 307586 |
| beta-lactamase production and resistance to beta-lactam antibiotics in nocardia. | although ampicillin has been suggested as a useful agent for the treatment of nocardiosis in man, little is known regarding the presence of beta-lactamase in nocardia or its possible role in determining resistance to ampicillin and the other beta-lactam antibiotics. we have evaluated 55 isolates of nocardia for susceptibility to five beta-lactam antibiotics and for the presence of beta-lactamase. nocardia were resistant to penicillin g, cloxacillin, and cefazolin, but 27 and 62% were susceptible ... | 1978 | 310280 |
| production of beta-lactamase by non-streptomyces actinomycetales. | supernatants and whole cells from fermentation broths of micromonospora, nocardia, oerskovia, and other genera of the actinomycetales were examined for the presence of beta-lactamase activity by using the chromogenic cephalosporin 87/312. nearly 60% of the 250 isolates examined produced detectable levels of beta-lactamase. all enzyme preparations were active over a range of ph values from 6.5 to 8.2, with maximum activity occurring between 7.0 and 7.8. the preparations varied in their stability ... | 1979 | 311614 |
| mycetoma in somalia - results of a survey done from 1959 to 1964. | the pasteur institute studied 103 mycetoma patients in somalia between 1959 and 1964. grains were seen in 94 of them and this, added to cultural features, allowed the diagnosis of 60 pathogens as follows: 44 madurella mycetomi, 1 leptosphaeria senegalensis, 7 pyrenochaeta romeroi (or madurella grisea), 3 allescheria boydii, 1 fusarium sp., 3 neotestudina (zopfia) rosatii, and 1 unidentified; 34 were actinomycetes: 24 streptomyces somaliensis, 4 actinomadura madurae, 3 a. pelletieri and 3 nocardi ... | 1977 | 23657 |
| human b cell differentiation. ii. suppression by t cells of t-dependent and t-independent plasma cell maturation. | in vitro human plasma cell generation induced by both t-dependent (pwm) and t-independent (nwsm) mitogens was found to be suppressed by peripheral blood lymphocytes preincubated with human aggregated igg. t cells, but not b lymphocytes, were able to mediate the suppressive activity; since aggregated (fab)'2 fragments were found unable to generate suppressor cells, it was concluded that the suppressor cell was a t lymphocyte bearing fcgamma receptors. these cells appeared to be largely radiosensi ... | 1979 | 312853 |
| microbial metabolism of aromatic nitriles. enzymology of c-n cleavage by nocardia sp. (rhodochrous group) n.c.i.b. 11216. | 1. an organism utilizing benzonitrile as sole carbon and nitrogen source was isolated by the enrichment-culture technique and identified as a nocardia sp. of the rhodochrous group. 2. respiration studies indicate that nitrile degradation proceeds through benzoic acid and catechol. 3. cell-free extracts of benzonitrile-grown cells contain an enzyme that catalyses the conversion of benzonitrile directly into benzoic acid without intermediate formation of benzamide. 4. this nitrilase enzyme was pur ... | 1977 | 21655 |
| further observations on an ether-o-oxidase, formerly called alkyl etherase, from liver tissue. | 1. the microsomal enzyme from liver previously called an "etherase" is now described more accurately as an ether-o-oxidase. it has been investigated further to free it from the membranes in aqueous solution and to try to define its physiological substrate. 2. after a variety of attempts with detergents, etc., the enzyme was obtained in impure solution from precipitation with 35-45% (nh4)2so4 solution after a short digestion at room temperature. 3. when a suitably reinforced the enzyme in solutio ... | 1977 | 17745 |
| frequencies of mitogen-reactive b cells in the mouse. lipopolysaccharide-, lipoprotein- and nocardia mitogen-reactive b cells in cba/n mice. | b cell-defective (cba/n x balb/c)f1 male mice have 100 times less lipopolysaccharide-reactive and 10--100 times less lipoprotein- and nocardia mitogen-reactive b cell precursors than f1 female mice with normal b cells. | 1979 | 316394 |
| comparative studies on cholesterol oxidases from different sources. | 1. comparison of the characteristics of cholesterol oxidases from different sources was made by a new polarographic method for measurement of the oxygen-consumption rate. 2. a ph optimum of 7.0 was observed for cholesterol oxidases isolated from nocardia and brevibacterium, ph 5.0 for the enzyme from schizophyllum and ph 7.5 for the enzyme from streptomyces. 3. in the system used in the present study, ca2+ and mg2+ had no effect on these enzyme activities. on the other hand, the schizophyllum en ... | 1976 | 11914 |
| chemistry of the ansamycin antibiotics. | | 1976 | 11155 |
| disseminated nocardia caviae infection. | disseminated nocardia caviae infection occurs only rarely. to date, two cases have been recorded in the literature. we describe a third case of systemic n. caviae infection in a compromised host and compare it with the first two cases. postmortem, microbiologic and antibiotic sensitivity data are included. | 1977 | 320868 |
| cell-mediated immunity in experimental nocardia asteroides infection. | experimental mycetoma-like lesions developed in guinea pigs after subcutaneous injection of nocardia asteroides. although delayed hypersensitivity appeared earlier, increased macrophage migration inhibition and microbicidal activity appeared after 7 weeks. when the lesions healed, high cell-mediated immunity was present. cell-mediated immunity was transferred to normal recipient guinea pigs from healed donor guinea pigs by spleen cell transfer. recipient guinea pigs showed marked protection agai ... | 1977 | 321348 |
| nocardia asteroides thenar space infection: a case report. | nocardia commonly is thought of as producing a chronic pulmonary or granulomatous skin infection, but this report illustrates that it may begin as an acute inflammatory process. in view of the tenosynovitis which followed exploration of the tendon sheath in the patient presented and which required a second operation, it may be better to aspirate the sheath at a distant site to look for pus. actinomycetes should be suspected and looked for with appropriate methods in any suppurative lesion, espec ... | 1977 | 321510 |
| in vitro response of rabbit alveolar macrophages to infection with nocardia asteroides. | the interaction of nocardia asteroides with cultured "normal" nonimmune rabbit alveolar macrophages was studied by light and electron microscopy. it was shown that the alveolar macrophage response to the more virulent strain (n. asteroides 14759) was quite different from the response to the less virulent organism (n. asteroides 10905). n. asteroides 14759 elicited a dramatic in vitro response of the macrophages toward the nocardial infection. within a few hours postinfection, there was a migrati ... | 1977 | 323145 |
| nocardia asteroides primary cerebral abscess and secondary meningitis. | a rare case of primary cerebral abscess due to nocardia asteroides, and its surgical removal, are described. postoperative meningitis caused by the same fungi was succesfully cured with sulphadiazine and cycloserine. the nocardial disease, its neurological complications, and therapy are reviewed. | 1977 | 327760 |
| studies of nocardia pellegrino sn 5108 pigment mutants: reasons for differences in pigmentation (author's transl). | yellow and white mutants of the strains nocardia pellegrino sn 5108 r have been isolated. regarding their morphological and physiological properties, the mutants are identical with the wild type bacteria with the exception of their pigmentation and lipid composition. however, the pigment composition (number, rf-values and spectra of the pigment components) of the yellow mutant is identical with that of the wild type; as a consequence, the modified pigmentation of the yellow mutant cannot be expl ... | 1976 | 3925 |
| new microbial growth factor. | a screening procedure was used to isolate from soil a penicillium sp., two bacterial isolates, and a streptomyces sp. that produced a new microbial growth factor. this factor was an absolute growth requirement for three soil bacteria. the penicillium sp. and one of the bacteria requiring the factor, an arthrobacter sp., were selected for more extensive study concerning the production and characteristics of the growth factor. it did not seem to be related to the siderochromes. it was not present ... | 1977 | 327929 |
| nocardia water-soluble mitogen and lipopolysaccharide. comparative study of two adjuvants and b-cell mitogens in mice. | the activity of nocardia water-soluble mitogen (nwsm) and lps were compared in several experimental systems, since both compounds are b-cell mitogens and polyclonal activators in vitro. the results reported here demonstrated that nwsm like lps also has a strong adjuvant activity in vivo if administered in saline with a strong antigen (heterologous red blood cells) or even with a weak immunogen such as theta alloantigen. however, in contrast to lps, nwsm administered to mice failed to induce in v ... | 1977 | 328390 |
| bilateral intraocular nocardia asteroides infection. | a 38-year-old man with hypogammaglobulinemia and pulmonary nocardia asteroides infection developed an intraocular nocardia infection. the diagnosis was confirmed by examination of a specimen removed at pars plana vitrectomy. the chorioretinal infection in one eye resolved partially, with no organisms visible on histopathologic examination of the globe at autopsy. one month before the patient's death from disseminated nocardial infection, the previously uninvolved right eye developed a new metast ... | 1977 | 329816 |
| effect of cyclophosphamide on experimental nocardia asteroides infection in mice. | it was found that cells of nocardia asteroides guh-2 (virulent) were approximately 10 times more virulent than cells of n. asteroides 14759 (intermediate) and greater that 500 times more virulent than n. asteroides 10905 (avirulent) cells when early-stationary-phase cultures suspended in saline were injected intravenously into "normal" mice. there appeared to be a specific organ tropism for each strain. thus, n. asteroides guh-2 infected primarily the kidneys, n. asteroides 14759 infected the l ... | 1977 | 330400 |
| fungal uveitis. | | 1977 | 330431 |
| the metabolism of cyclohexanol by acinetobacter ncib 9871. | acinetobacter ncib 9871 was isolated by elective culture on cyclohexanol and grows with this compound as sole source of carbon. it displays a restricted growth spectrum, being unable to grow on a wide range of alternative alicyclic alcohols and ketones. cyclohexanol-grown cells oxidize the growth substrate at a rate of 230 mul of o2/h per mg dry wt with the consumption of 5.65 mumol of o2/mumol substrate. cyclohexanone is oxidized at a similar rate with the consumption of 4.85 mumol of o2/mumol. ... | 1975 | 1261 |
| cell-mediated immunity to nocardia asteroides induced by its ribonucleic acid protein fraction. | guinea pigs immunized with ribonucleic acid protein fraction from nocardia asteroides developed high cell-mediated immunity within 2 weeks, as shown by increased macrophage microbicidal activity and macrophage migration inhibition. this immunity protected against intravenous and subcutaneous challenge with n. asteroides and persisted for at least 70 days. | 1977 | 332642 |
| nocardioform bacteria. | | 1977 | 334037 |
| nocardia asteroides sinusitis. presentation as a trimethoprim-sulfamethoxazole responsive fever of unknown origin. | a patient with a yearlong fever of unknown origin responded to trimethoprim-sulfamethoxazole and was discovered to have culture-proved nocardia asteroides sinusitis, with absence of detectable disease in other organs. an inhalational route is postulated as the mode of entry of the organism, with localization in the maxillary sinus. | 1977 | 335095 |
| phospholipid composition of nocardia species. | | 1977 | 336530 |
| nocardia infections in congenitally athymic (nude) mice and in other inbred mouse strains. | the mortality rate and histopathological features of nocardia asteroides and nocardia brasiliensis infections in congenitally athymic (nude) mice of icr and c3h/eb origins were quite different from what we found for swiss white mice and other inbred mouse strains (namely, c57/bl/6j, new zealand black, balb/c, cba/lac, and c3h/eb). the immunocompetent littermates of the congenitally athymic mice occupied an intermediate position between their athymic siblings and swiss white mice in terms of thei ... | 1977 | 336547 |
| antibody response in rabbits to immunization with mycobacterium leprae. | mycobacterium leprae purified from liver tissue of an infected armadillo (the a/10 preparation) was tested for antigenic composition by immunization of rabbits and characterization of the antibody response by crossed immunoelectrophoresis. the rabbit antisera detected seven distinct components in the m. leprae preparation. this number is far lower than in similar experiments with other mycobacteria. the m. leprae sonic extract gave far fewer lines after polyacrylamide gel electrophoresis and sta ... | 1977 | 338491 |
| case records of the massachusetts general hospital. weekly clinicopathological exercises. case 2--1978. | | 1978 | 339083 |