| numerical analysis of relationships among rapidly growing, scotochromogenic mycobacteria. | numerical analysis of the relationships among rapidly growing, scotochromogenic mycobacteria was carried out; a dendrogram was prepared by a single linkage method and the separation between species was tested. the following were distinct species: mycobacterium alichiense; mycobacterium rhodesiae;mycobacterium chubuense; mycobacterium obuense; mycobacterium gilvum; mycobacterium duvalii; mycobacterium flavescens; and mycobacterium vaccae. mycobacterium tokaiense was reduced to a synonym of m. chu ... | 1977 | 853289 |
| mycobacterium obuense, a rapidly growing scotochromogenic mycobacterium capable of forming a black product from p-aminosalicylate and salicylate. | | 1971 | 5136244 |
| a mycobacterium isolated from tissue cultures of mature pinus sylvestris interferes with growth of scots pine seedlings. | we isolated a rapidly growing, pigment-producing mycobacterium from senescent tissue cultures derived from mature scots pine (pinus sylvestris l.). the bacterium was found in three senescent suspension cultures and in a senescent protoplast culture. growth of scots pine cells had ceased in all of these cultures. exogenous contamination was eliminated by rigorous surface sterilization of the buds with hypochlorite before aseptic removal of the bud scales. based on biochemical and physiological pr ... | 2000 | 11303582 |
| surface spreading motility shown by a group of phylogenetically related, rapidly growing pigmented mycobacteria suggests that motility is a common property of mycobacterial species but is restricted to smooth colonies. | motility in mycobacteria was described for the first time in 1999. it was reported that mycobacterium smegmatis and mycobacterium avium could spread on the surface of solid growth medium by a sliding mechanism and that the presence of cell wall glycopeptidolipids was essential for motility. we recently reported that mycobacterium vaccae can also spread on growth medium surfaces; however, only smooth colonies presented this property. smooth colonies of m. vaccae do not produce glycopeptidolipids ... | 2008 | 18689490 |
| mycobacteria activate γδ t-cell anti-tumour responses via cytokines from type 1 myeloid dendritic cells: a mechanism of action for cancer immunotherapy. | attenuated and heat-killed mycobacteria display demonstrable activity against cancer in the clinic; however, the induced immune response is poorly characterised and potential biomarkers of response ill-defined. we investigated whether three mycobacterial preparations currently used in the clinic (bcg and heat-killed mycobacterium vaccae and mycobacterium obuense) can stimulate anti-tumour effector responses in human γδ t-cells. γδ t-cell responses were characterised by measuring cytokine product ... | 2011 | 22002242 |
| reductive dechlorination of methoxychlor by bacterial species of environmental origin: evidence for primary biodegradation of methoxychlor in submerged environments. | methoxychlor [1,1,1-trichloro-2,2-bis(4-methoxyphenyl)ethane] is an organochlorine insecticide that undergoes dechlorination in natural submerged environments. we investigated the ability to dechlorinate this compound in seven environmental bacterial species ( aeromonas hydrophila , enterobacter amnigenus , klebsiella terrigena , bacillus subtilis , achromobacter xylosoxidans , acinetobacter calcoaceticus , and mycobacterium obuense ) and the enteric bacterium escherichia coli as a positive cont ... | 2012 | 22292429 |
| microbiological quality and occurrence of nontuberculous mycobacteria in fresh-squeezed orange juice samples purchased from street vendors in mexico city. | nontuberculous mycobacteria (ntm) are potentially pathogenic agents commonly found in a natural ecosystem. for this reason, food is considered another source of ntm transmission for humans. the aims of this study were to evaluate the microbiological quality and the occurrence of ntm in fresh-squeezed orange juice samples purchased from street vendors. all 102 samples analyzed were positive for aerobic mesophilic bacteria (amb), with limits ranging from 1.8 to 6.2 log cfu/ml. a total of 55 (54%), ... | 2016 | 28221956 |
| immunomodulatory effects of heat-killed mycobacterium obuense on human blood dendritic cells. | heat-killed (hk) mycobacterium obuense is a novel immunomodulator, currently undergoing clinical evaluation as an immunotherapeutic agent in the treatment of cancer. here, we examined the effect of in vitro exposure to hk m. obuense on the expression of different categories of surface receptors on human blood myeloid (m) and plasmacytoid (p) dcs. moreover, we have characterized the cytokine and chemokine secretion patterns of purified total blood dcs stimulated with hk m. obuense. hk m. obuense ... | 2017 | 28853313 |
| randomised, open-label, phase ii study of gemcitabine with and without imm-101 for advanced pancreatic cancer. | immune modulation and gemcitabine evaluation-1, a randomised, open-label, phase ii, first-line, proof of concept study (nct01303172), explored safety and tolerability of imm-101 (heat-killed mycobacterium obuense; nctc 13365) with gemcitabine (gem) in advanced pancreatic ductal adenocarcinoma. | 2016 | 27599039 |
| draft genome sequence of mycobacterium obuense strain uc1, isolated from patient sputum. | we report the draft genome sequence of mycobacterium obuense strain uc1 from a patient sputum sample. this is the first draft genome sequence of mycobacterium obuense, a rapidly growing scotochromogenic mycobacterium. | 2015 | 26067960 |
| characterization of three mycobacterium spp. with potential use in bioremediation by genome sequencing and comparative genomics. | we provide the genome sequences of the type strains of the polychlorophenol-degrading mycobacterium chlorophenolicum (dsm43826), the degrader of chlorinated aliphatics mycobacterium chubuense (dsm44219) and mycobacterium obuense (dsm44075) that has been tested for use in cancer immunotherapy. the genome sizes of m. chlorophenolicum, m. chubuense, and m. obuense are 6.93, 5.95, and 5.58 mb with gc-contents of 68.4%, 69.2%, and 67.9%, respectively. comparative genomic analysis revealed that 3,254 ... | 2015 | 26079817 |