| infections with mycobacterium malmoense in england and wales. | mycobacterium malmoense has been isolated from 11 patients in england and wales. it was thought to be the cause of pulmonary disease in 9 of them and cervical adenitis in 2. the cultural and biochemical characters of the species are described and its position in relation to the avium-intracellulare complex and the non-chromogenicum-terrae-triviale complex determined by matching coefficients using 88 characters. brief details are given of the 11 cases. | 1979 | 473379 |
| mycobacterium malmoense type ii bacteraemia contributing to death in a patient with aids. | | 1992 | 1283700 |
| [mycobacterium malmoense infection of the flexor tendon sheath]. | infections of the tendon sheath caused by non-tuberculous mycobacteria are well known. so far, only one case involving mycobacterium malmoense has been reported. the authors report of a 73-year old patient having undergone carpal tunnel release. in spite of granulomatous inflammation of the flexor tendon sheaths, there was no biopsy cultured for acid-fast bacteria. one year later, symptoms recurred and synovialectomy was repeated. in spite of macroscopic appearance of the synovialis and histolog ... | 1992 | 1516857 |
| fourth report of the cooperative, open-ended study of slowly growing mycobacteria by the international working group on mycobacterial taxonomy. | the open-ended study of the international working group on mycobacterial taxonomy is an ongoing project to characterize slowly growing strains of mycobacteria that do not belong to well-established or thoroughly characterized species. in this fourth report we describe two numerical taxonomic clusters that represent subspecies or biovars of mycobacterium simiae, one cluster that encompasses the erstwhile type strain of the presently invalid species "mycobacterium paraffinicum," one cluster that i ... | 1991 | 1742195 |
| [diagnosis and treatment of pulmonary infection due to mycobacterium malmoense]. | to date more than 150 patients with mycobacterium malmoense disease have been reported. these infections are rare and only in one case, so far not published, is this species associated with aids. most reported cases were seen in northern europe. we present three pulmonary cases from switzerland. m. malmoense causes lung disease resembling tuberculosis clinically and in chest x-ray. disease is considered to be present when two and more sputums or bronchial washings are acid-fast bacilli smear-pos ... | 1991 | 1745892 |
| mycobacterium malmoense infection in hiv positive patients. | mycobacterium malmoense is a non-tuberculous mycobacterium which has previously been associated with underlying pulmonary pathology and depressed immunity. we describe two patients infected with human immunodeficiency virus from whom m. malmoense was isolated, and discuss its treatment and possible pathogenic role. | 1991 | 1753120 |
| pulmonary disease caused by mycobacterium malmoense. comments on the possible origin of infection and methods for laboratory diagnosis. | mycobacterium malmoense was isolated from sputum and gastric lavage from a 68-year-old man with gastric adenocarcinoma. the patient meets the criteria for diagnosis of pulmonary mycobacteriosis. the cultural, physiological and biochemical properties of the isolates were compared with other slowly growing mycobacterial species. fatty and mycolic acid analyses revealed the presence of 2-methyleicosanoic and 2,4,6-trimethyltetracosanoic acids and alpha-, alpha'-and ketomycolates, all regarded as ty ... | 1991 | 1771683 |
| mycobacterium malmoense: an easily missed pathogen. | the bactec system (becton dickinson, sparks, md.) was compared with culture on löwenstein-jensen egg medium for the detection of mycobacterium malmoense in lymph node samples from children with lymphadenitis. it was found to be significantly more sensitive and rapid. the use of the bactec system is thus recommended as a complement to culture on solid media for the primary isolation of atypical mycobacteria, such as m. malmoense. | 1991 | 1774286 |
| increased growth of mycobacterium malmoense in vitro in the presence of isoniazid. | | 1991 | 1810740 |
| mycobacterium malmoense infections. | | 1991 | 1858418 |
| chemotypes of mycobacterium malmoense based on glycolipid profiles. | thin-layer chromatographic analysis of 72 finnish clinical mycobacterial isolates presumptively identified as mycobacterium malmoense revealed four major glycolipid profiles with two minor variations. an additional glycolipid profile was found in three british m. malmoense-like strains. no clear distinction between the strains could be made by means of gas chromatography of cellular fatty acids. the two m. malmoense-specific constituents, 2-methyleicosanoate and 2,4,6-trimethyltetracosanoate, we ... | 1991 | 2007643 |
| [hairy cell leukemia and mycobacterium malmoense infection]. | we describe a patient with hairy cell leukemia and protracted fever. the patient's condition deteriorated during treatment with alfa interferon 2b, and his fever persisted. a slight widening of the upper mediastinum appeared after 2.5 months. mediastinoscopy with lymph node biopsy revealed granulomatous infiltrates with acid-fast bacilli. cultures of the lymph node material later showed growth of mycobacterium malmoense. the patient was treated with rifampicin, doxycycline, etambutol and cyclose ... | 1990 | 2321208 |
| cutaneous mycobacterium malmoense infection in an immunocompromised patient. | | 1990 | 2323872 |
| [atypical mycobacterioses: diseases caused by mycobacterium malmoense]. | m. malmoense, once a rarity among the atypical mycobacterial infections, is presently being detected with ever greater frequency in human examination material. strains of this organism apparently belong to the facultative pathogenic mycobacteria, as the cases described in this article show. apart from other patients with mycobacterial infections of the lungs, the first case of infection of the lymph nodes in the neck is described. | 1990 | 2326246 |
| structure of mycobacteria: recent developments in defining cell wall carbohydrates and proteins. | work from this laboratory on the immunogens of mycobacterium species has focused on those based on carbohydrates (with a view to the development of specific tools for the serodiagnosis of mycobacterioses) and on the cell-wall proteins, as a source of protective immunity and as a means of observing specific delayed-type hypersensitivity. most mycobacteria are endowed with specific, highly antigenic glycolipids that are powerful for the serodiagnosis of individual mycobacterial infections: e.g., t ... | 1989 | 2469120 |
| enhancement of growth of mycobacterium malmoense by acidic ph and pyruvate. | the growth of mycobacterium malmoense is dysgonic and slow on ordinary mycobacterium media. the effect of ph and pyruvate on the growth of ten strains was studied on a modification of löwenstein-jensen medium. growth appeared sooner and was more abundant at ph less than 6.5. at ph 7 or higher, it was scarcely or not at all visible after six weeks of incubation. pyruvate enhanced the growth of five strains that grew only poorly on glycerol-containing medium, even at acidic ph. the parallel use of ... | 1989 | 2513203 |
| difficulty with mycobacterium malmoense. | | 1989 | 2570222 |
| [differentiation between mycobacterium malmoense and mycobacterium nonchromogenicum by ethambutol susceptibility]. | mycobacterium malmoense strains are resistant to 1 microgram/ml ethambutol in ogawa egg medium, whereas mycobacterium nonchromogenicum strains are susceptible to this concentration. therefore, these two group iii nonphotochromogens are differentiated clearly from each other by the susceptibility test for ethambutol 1 microgram/ml. ninety-five % of mycobacterium avium complex strains are resistant to this concentration, while m. nonchromogenicum strains are susceptible. therefore, the test serves ... | 1989 | 2733305 |
| mycobacterium malmoense infection presenting as a mediastinal mass in a child. | | 1989 | 2778346 |
| a mycobacterium malmoense infection of the hand presenting as carpal tunnel syndrome. | we report an atypical tuberculous infection by mycobacterium malmoense of the synovium of the flexor tendons at the wrist presenting as carpal tunnel syndrome. this is the first time this organism has been described in a site other than the lungs or the cervical lymph nodes. | 1988 | 3171306 |
| [human infections caused by mycobacterium malmoense]. | | 1988 | 3286958 |
| mycobacteria other than mycobacterium tuberculosis: review of microbiologic and clinical aspects. | the rate of isolation of mycobacteria other than mycobacterium tuberculosis (mott) has increased over the past several years; in some areas the isolation rate for mycobacterium avium-mycobacterium intracellulare has surpassed that for m. tuberculosis. simultaneously, the spectrum of clinical manifestations with the various species has widened. outbreaks of disease due to mycobacterium chelonae have occurred in renal dialysis patients. new species have been described: mycobacterium malmoense is p ... | 1987 | 3296098 |
| fatty and mycolic acids of mycobacterium malmoense. | the fatty acids and mycolic acids of 16 clinical isolates of mycobacterium malmoense were studied by gas chromatography and thin-layer chromatography. all strains contained 2-methyleicosanoic and 2,4,6-trimethyltetracosanoic acids and alpha-, alpha'-, and keto-mycolic acids. the reported findings suggest that lipid analysis is a very useful approach in the species identification of m. malmoense. | 1988 | 3343309 |
| combined versus single antituberculosis drugs on the in vitro sensitivity patterns of non-tuberculous mycobacteria. | drug sensitivity tests were performed for ethambutol, rifampicin, streptomycin, and isoniazid both alone and in paired combinations, on 16 strains of mycobacterium avium intracellulare, seven strains of mycobacterium xenopi, and eight strains of mycobacterium malmoense. most strains were resistant to the individual drugs, but all strains of m malmoense, 86% of m xenopi, and 31% of m avium intracellulare were completely suppressed by the lowest concentrations of ethambutol and rifampicin when the ... | 1987 | 3424264 |
| pulmonary disease caused by mycobacterium malmoense. | mycobacterium malmoense was isolated from pulmonary material from 4 patients. two patients had repeatedly positive smears and cultures along with roentgenographic progression of pulmonary disease in the absence of another pathogen. these 2 patients therefore meet the criteria for diagnosis of pulmonary mycobacteriosis. isolation of the organism may represent colonization in a third patient, and m. malmoense has been isolated from a fourth patient on 2 occasions. it is not yet definite, however, ... | 1987 | 3592410 |
| definition of the surface antigens of mycobacterium malmoense and use in studying the etiology of a form of mycobacteriosis. | mycobacterium malmoense is the latest of a roster of atypical mycobacteria implicated in pulmonary infections. yet it lacks recognizable phenotypic features to allow its ready identification. some 23 clinical isolates of m. malmoense were examined for homologous seroagglutination reactions and characteristic surface antigens. one group showed concordant agglutination interreactions and an identical spectrum of glycolipids and are regarded as m. malmoense sensu stricto. the glycolipids are of the ... | 1987 | 3597323 |
| [pulmonary infection caused by a rare mycobacterium, mycobacterium malmoënse]. | the present case report is on a patient treated for tubercle in 1949 by an artificial pneumothorax. thirty three years after the initial illness some radiological changes occurred suggesting a recurrence, especially as a bacteriological examination showed the presence of acid-alcohol fast bacilli on direct smear. triple therapy (isoniazid, rifampicin, streptomycin) was then prescribed, and was followed by a radiological improvement, even though the sputum remained positive. after multiple seedin ... | 1987 | 3616119 |
| mycobacterium malmoense--report of a case in switzerland. | mycobacterium malmoense was isolated in four different sputum samples of a 45-year-old alcoholic smoker. the biochemical and culture characteristics of this species are described and compared with a reference strain (atcc 29571). the isolated strain was sensitive in vitro to rifampicine, ethionamide, kanamycine and erythromycin. therapy consisted of right-upper-lobe lobectomy and a two-year antimicrobial therapy. there was no sign of relapse at the end of the treatment period. | 1987 | 3659578 |
| mycobacterium malmoense infections in scotland: an increasing problem. | during 1982-4 20 cases of mycobacterium malmoense infection were identified in scotland (13 male, seven female; age 34-82, median 62 years). features of the disease were obtained from case notes and radiographs of 19 patients and were found to be indistinguishable from those of patients with pulmonary tuberculosis. chronic chest disease, predominantly chronic airflow obstruction, was the most frequent associated disease. the organisms showed in vitro resistance in eight patients to rifampicin, i ... | 1987 | 3660312 |
| mycobacterium malmoense: mycobacteriologic concerns. | | 1987 | 3674593 |
| mycobacterium malmoense. | | 1985 | 3901452 |
| rapid and sensitive identification of mycobacterium tuberculosis. | the fatty acid constituents of 14 species of mycobacterium (14 isolates) and one isolate each of corynebacterium xerosis, nocardia asteroides, and streptomyces albus were examined with the purpose of distinguishing mycobacterium tuberculosis from other acid-fast bacilli. combined thin-layer chromatography (tlc) of methyl mycolates and gas-liquid chromatography (glc) of shorter-chain fatty acid esters provided an unequivocal identification of m. tuberculosis in a matter of 2 to 3 days. the method ... | 1985 | 3932458 |
| pulmonary infection with mycobacterium malmoense--a review of treatment and response. | thirty seven patients whose sputum cultures had yielded positive isolates of mycobacterium malmoense during the years 1978-1983 have been reviewed. significant pulmonary infection was present in 34 patients (92%), 3 of whom had only single isolates cultured from their sputum. the significance of isolates in the remaining 3 patients was not established. there was pre-existing pulmonary disease in 22 patients and another 4 were taking immuno-suppressive drugs. various drug regimens were used to tr ... | 1985 | 4049531 |
| pulmonary infection with mycobacterium malmoense: a report of 4 cases. | four cases of pulmonary infection with mycobacterium malmoense are presented. the clinical features are described and the significance of this organism in producing pulmonary disease is discussed. | 1985 | 4049532 |
| mycobacterium malmoense in the north-east of england. | we report a 6 year experience (1979-1984) of isolating mycobacterium malmoense in the north-east of england. eleven subjects were involved of whom 10 had active infection--9 pulmonary, one cervical adenitis. the 11 new isolates represent 0.7% of all new mycobacterial isolates during this period and 10% of new non-tuberculous isolates. in all but 2 cases there was pre-existing pulmonary disease and/or a recognised predisposing factor to mycobacterial infection. the organisms were generally insens ... | 1985 | 4049533 |
| [pulmonary mycobacteriosis due to a non-chromogenic, slow-growing, unclassified mycobacterium]. | a case is reported of a bilateral atypical mycobacterial infection, occurring in a 44 year old male with antecedent silicosis. successful surgical resection was performed after 17 months of failed chemotherapy. the atypical mycobacterium which is unclassified is intermediate between mycobacterium avium-intracellulare. mycobacterium terrae complex and mycobacterium gastri. it has some similarities with the newly described species, mycobacterium malmöense. | 1984 | 6473887 |
| pulmonary disease due to mycobacterium malmoense. | a case of pulmonary disease due to mycobacterium malmoense was recently diagnosed in a 43-year-old man from virginia. this organism was isolated from sputum and bronchial washings. this is the first case of documented human infection due to this organism in the united states | 1984 | 6490817 |
| mycobacterium malmoense--problems with treatment and diagnosis--a case report. | | 1983 | 6636306 |
| pneumonectomy for drug resistant mycobacterium malmoense. | | 1983 | 6648861 |
| [mycobacterium malmoense in the federal republic of germany]. | for the first time m. malmoense was demonstrated in sweden, thereafter in wales (gb) and finland. lately we have also found lung diseases in germany. m. malmoense is very difficult to identify because same characteristics are instable and optimal cultivation conditions could not be obtained so far. agglutination with homologous antisera was found to be specific for m. malmoense as well as lipid patterns which could be demonstrated by dc. | 1982 | 7164636 |
| the epidemiology of opportunist mycobacterial infections in wales, 1952--1978. | the incidence of infections caused by opportunist mycobacteria in wales during the years 1952--1978 was derived from the records of the mycobacterium reference unit in cardiff. mycobacterium kansasil gave rise to 154 pulmonary and two nonpulmonary infections. most of these patients were middle-aged men, approximately half of whom had pneumoconiosis or occupational exposure to dust. organisms of the mycobacterium avium-intracellulare-scrofulaceum complex caused pulmonary disease in 44 subjects an ... | 1981 | 7339797 |
| utility of high-performance liquid chromatography for identification of mycobacterial species rarely encountered in clinical laboratories. | high-performance liquid chromatography (hplc) has been demonstrated to be a suitable technique for determining the species of mycobacteria on the basis of their mycolic acid pattern. representative hplc profiles, which are needed for the visual recognition of chromatograms, have been published for the most frequently encountered mycobacterial species. no extensive study has been reported for less common species, and only a few, scattered chromatographic patterns are available in literature. this ... | 1995 | 7614969 |
| [pulmonary pathology and an infrequent mycobacterium malmoense]. | | 1995 | 7620071 |
| non-tuberculous mycobacterial infections presenting as salivary gland masses in children: investigation and conservative management. | non-tuberculous mycobacterial (ntm) infections in children commonly present as cervicofacial masses. the importance of early diagnosis is in the exclusion of infection requiring treatment, particularly tuberculosis and the rare case of malignancy. five children with ntm presenting with salivary gland masses illustrate the value of skin testing with new tuberculins and the place of fine-needle aspiration cytology in the investigation of these infections. four children who were skin tested reacted ... | 1995 | 7642993 |
| pulmonary infections caused by less frequently encountered slow-growing environmental mycobacteria. | pulmonary mycobacteriosis is usually caused by mycobacterium tuberculosis or mycobacterium avium complex. there are, however, other slow-growing mycobacteria that can cause pulmonary infection. mycobacterium kansasii, mycobacterium malmoense, mycobacterium xenopi, mycobacterium szulgai and mycobacterium simiae typically infect middle-aged to elderly persons with preexisting lung disease. differentiation of infection with these five mycobacteria from infection with mycobacterium tuberculosis, by ... | 1994 | 7698120 |
| pulmonary mycobacterium malmoense and aspergillus infection. | | 1995 | 7701472 |
| isolation of mycobacterium malmoense from the environment in zaire. | two strains of mycobacteria isolated from water and soil in zaire were identified as mycobacterium malmoense by biochemical tests and lipid analysis. apart from the previously reported fatty acids characteristic of this species, both strains, as well as 5 clinical isolates of m. malmoense, contained 2,4-dimethyl-docosanoic acid. one of the environmental strains, with a glycolipid pattern ii, additionally contained 2-methyltetradecanoic acid. the results confirm that m. malmoense may be subdivide ... | 1995 | 7780099 |
| mycobacterium malmoense in italy. | a case of mycobacterial lymphadenitis due to mycobacterium malmoense was recently diagnosed in a 5-year-old girl. the organism was isolated from pus and tissue fragments obtained by surgical excision of the affected nodes. this is the first documented case of human infection due to this organism in italy. | 1995 | 7780102 |
| faster identification of mycobacteria using gas liquid and thin layer chromatography. | gas liquid chromatography (glc) and thin layer chromatography (tlc) analysis of cell wall content was used for identification of mycobacteria isolated in primary cultures. glc permitted determination of the fatty acid and alcohol profiles of mycobacterium simiae and mycobacterium marinum and detection of a peak in mycobacterium ulcerans formerly described for mycobacterium malmoense. using the data obtained to fill some of the gaps in the dichotomic trees of tisdall et al. and jantzen et al., gl ... | 1994 | 7843176 |
| random amplified polymorphic dna genotyping of mycobacterium malmoense. | the suitability of random amplified polymorphic dna-pcr for the detection of differences between mycobacterium malmoense strains was evaluated. with two of the 32 tested primers seven fingerprint patterns which proved excellent in distinguishing intraspecies variations of m. malmoense were obtained. the combination of the results obtained with the two primers permitted a clear separation of the strains. this technique is useful for analyzing species whose dna sequences are not known. it can easi ... | 1994 | 7929785 |
| mycobacterium malmoense isolated from soil. | mycobacterium malmoense was isolated from a soil sample, and biological, biochemical, antigenic, and genetic characteristics of the isolate were described. this is the first report of isolation of this organism in japan. | 1994 | 7935052 |
| disseminated infection due to mycobacterium malmoense in a patient infected with human immunodeficiency virus. | | 1994 | 7948532 |
| septic cutaneous lesions caused by mycobacterium malmoense in a patient with hairy cell leukemia. | patients with hairy cell leukemia seem to be prone to infections with mycobacteria. this report describes a patient with hairy cell leukemia and pulmonary infection as well as disseminated cutaneous infection caused by mycobacterium malmoense cultured from sputum and skin scrapings on loewenstein-jensen medium in eight weeks. despite multiresistance of the causative strain, the infection was successfully treated with ethambutol, cycloserine and isoniazid. | 1994 | 8013487 |
| pulmonary mycobacterium malmoense and aspergillus infection: a fatal combination? | three patients with chronic obstructive pulmonary disease developed coexisting mycobacterium malmoense and aspergillus infection. all suffered progressive lung destruction leading to early death despite prolonged antimycobacterial chemotherapy. | 1994 | 8016779 |
| infection with mycobacterium malmoense in sweden: report of 221 cases. | mycobacterium malmoense was first described in 1977 and today is second only to the mycobacterium avium complex as a cause of atypical mycobacterial infection in sweden. we retrospectively studied the records of 221 patients from whom m. malmoense was isolated during 1968-1989. m. malmoense was recovered from the respiratory tract of 171 patients (170 adults and one child) and from cervical lymph nodes of 36 patients (35 children and one adult). in addition, the organism was isolated from the ur ... | 1994 | 8038315 |
| mycobacterium malmoense and carcinoma of lung. | | 1994 | 8091337 |
| pseudotumour of the lung caused by mycobacterium malmoense infection in an hiv positive patient. | | 1994 | 8128410 |
| [cervical lymphadenitis due to mycobacterium malmoense in a child: case report and differential diagnosis of cervical lymphadenitis and lymphadenopathies]. | cervical lymphadenitis and lymphadenopathy are common in children and may be caused by local or systemic infection. there are a large number of possible etiologies. we report the case of a five-year-old boy with unilateral cervical lymphadenitis who was in good health and showed neither clinical nor laboratory signs of systemic infection. despite repetitive empirical antimicrobial treatment, the lymph nodes increased in size. after surgical excision mycobacterium malmoense grew from the lymph no ... | 1993 | 8211027 |
| disseminated mycobacterium malmoense infection in a patient with chronic granulocytic leukaemia. | mycobacterium malmoense is an atypical mycobacterium previously isolated from lymph nodes in children and from adults with pulmonary disease. disseminated infection is extremely rare and bone marrow involvement has never previously been described. we report a patient with chronic granulocytic leukaemia and persistent fever with granuloma in the bone marrow due to disseminated m. malmoense infection. the patient initially received treatment with isoniazid, ethambutol and rifampicin with clearance ... | 1993 | 8340748 |
| isolation of mycobacterium malmoense from hiv-positive patients. | | 1993 | 8347226 |
| pulmonary infections caused by mycobacterium malmoense and mycobacterium tuberculosis: comparison of radiographic features. | the purpose of this study was to compare the radiographic features seen at presentation of pulmonary infections caused by mycobacterium malmoense and mycobacterium tuberculosis. the correct differential diagnosis has important therapeutic implications. | 1993 | 8372747 |
| extrapulmonary and disseminated infections due to mycobacterium malmoense: case report and review. | mycobacterium malmoense is a potentially pathogenic species that was first described in 1977. during the past decade m. malmoense has been recognized with increasing frequency as a pulmonary pathogen. more than 180 cases of m. malmoense infection have been reported. most of these infections affected a previously damaged lung. other infection sites included the skin, lymph nodes, and bursae. five cases of disseminated infection have been reported. the antituberculous drugs associated with the mos ... | 1993 | 8390306 |
| susceptibility of mycobacterium malmoense to antibacterial drugs and drug combinations. | mycobacterium malmoense is an opportunistic pathogen with increasingly recognized clinical importance. it is mainly isolated in northern europe and great britain, most often from patients with pulmonary infections. conventional therapy of m. malmoense infections with antituberculosis drugs is often of limited value, and there is thus a need for improved drug regimens. the potential efficacies of new alternative drugs, such as quinolones, macrolides, amikacin, and rifabutin, are still unknown, an ... | 1993 | 8392308 |
| cutaneous infection caused by mycobacterium malmoense in a patient with myelodysplastic syndrome. | | 1993 | 8433292 |
| mycobacterium malmoense infection in an immunocompromised patient. | | 1993 | 8473773 |
| [opportunistic lung infections in patients with chronic obstructive lung disease; a side effect of inhalation corticosteroids?]. | in four patients, men of 64, 66 and 69 years old and a woman of 65 years, who suffered from chronic obstructive pulmonary disease (copd) and used inhalation corticosteroids in a relatively high dose (800-1600 micrograms of budesonide per day), a pulmonary infection was diagnosed caused by mycobacterium malmoense (the first two patients) and aspergillus (the other two) respectively. inhalation corticosteroids are of great importance in the treatment of asthmatic patients. their place in the treat ... | 1996 | 8569928 |
| a symptomatic atypical mycobacterial infection masquerading as a vascular ring on chest x-ray. | atypical mycobacterium is rare in children. there are few case reports of childhood pulmonary diseases caused by atypical mycobacterium. the case of a 20-month-old boy who had stridor and respiratory distress is presented. chest x-ray showed right-sided narrowing of the trachea and left-sided aortic knob. ziehl-neelsen stain showed acid-fast bacilli. the culture showed mycobacterium malmoense. | 1996 | 8640587 |
| bronchopulmonary infection with mycobacterium malmoense presenting as a bronchoesophageal fistula. | we report a bronchopulmonary infection with mycobacterium malmoense in a patient with severe immunosuppression due to insulin-dependent diabetes mellitus, humoral immunodeficiency after thymoma (good's syndrome) and prolonged immunosuppressive treatment after myasthenic crisis. it presented as non-resolving pneumonia of the left lower lobe. bronchoscopically, a bronchoesophageal fistula was detected. numerous acid-fast organisms were found in the sputum specimen and in the bronchial biopsy aroun ... | 1996 | 8758116 |
| mycobacterium malmoense bacteremia in two aids patients. | we report two cases of mycobacterium malmoense bacteremia in two patients with aids. these are the first reported cases of disseminated m. malmoense in human immunodeficiency virus patients occurring in the united states. this slow-growing organism can cause invasive disease mimicking mycobacterium avium complex infection; recognition and identification of this organism by mycobacteriology laboratories are essential for appropriate diagnosis and therapy of disseminated disease. | 1996 | 8904448 |
| a mycobacterium malmoense-specific dna probe from the 16s/23s rrna intergenic spacer region. | mycobacterium malmoense was first described in 1977. it is now recognized as an opportunistic human pathogen which can be difficult to identify using standard methods. m. malmoense may be underestimated as the causative agent of clinical disease because of the recognized difficulties in its primary cultivation and identification. in this study, the nucleotide sequence of the 16s/23s rrna intergenic spacer region from five clinical isolates of m. malmoense has been determined, in order to develop ... | 1996 | 8910888 |
| slowly growing mycobacteria and chronic skin disorders. | we evaluated the role of mycobacteria in chronic skin manifestations. the etiologies of chronic skin disorders in 90 patients were analyzed by culture, histopathologic examination, and skin testing for mycobacteria. there were 20 clinical diagnoses; prurigo nodularis was the most common diagnosis (43 patients). cultures were incubated at 32 degrees c and 36 degrees c for 6 months. fourteen cultures (16%) yielded the following mycobacteria: mycobacterium tuberculosis (5), mycobacterium avium/myco ... | 1996 | 8922800 |
| application of a pcr based dna probe for the rapid identification of mycobacterium malmoense isolated from a case of cervical adenitis. | | 1996 | 8945716 |
| pyrolysis mass spectrometry: a predictor of clinical response to treatment in pulmonary opportunist mycobacterial infection: preliminary work with m. malmoense. | pyrolysis mass spectrometry (py-ms) yields data reflecting overall cell composition. the changes in composition induced by treatment with rifampicin and ethambutol, alone and in combination, were investigated for a collection of seven strains of mycobacterium malmoense from pulmonary infections. two strains, both from patients that had responded to therapy with this combination, showed large changes in composition from control, untreated cultures. the difference was particularly marked for the e ... | 1997 | 9060162 |
| [pulmonary infection by mycobacterium malmoense in a patient with aids]. | | 1997 | 9147514 |
| flexor tenosynovitis in the hand caused by mycobacterium malmoense: a case report. | this report analyzes a rare case of flexor tenosynovitis caused by mycobacterium malmoense. a synovectomy was carried out on the index finger (no other finger was afflicted) of a 66-year-old farmer, followed by antibiotic therapy with ethambutol, rifampin, and clarithromycin. because of strong side effects, the treatment with ethambutol and rifampicin had to be discontinued after 4 months. there was no recurrence after 14 months, and the patient's finger had a full range of motion. | 1997 | 9195437 |
| mycobacterium malmoense in italy: the modern norman invasion? | the isolation of mycobacterium malmoense has for a long time been restricted to few countries of northern europe; reports from countries other than sweden, great britain and finland are rare and the first italian case report has been published in 1995. since 1988, however, fifteen strains of m. malmoense have been isolated in italy, eleven of which in the last two years; of these, ten appeared clinically significant on the basis of medical records. the susceptibility of the strains and the role ... | 1997 | 9258535 |
| determination of the etiology of presumptive feline leprosy by 16s rrna gene analysis. | pcr-amplified 16s rrna gene sequences were obtained directly from tissue specimens from eight cats with presumptive feline leprosy. acid-fast bacilli were observed in sections from all eight specimens, but culture for mycobacteria was successful for one specimen only. analysis of the v2 variable region of each 16s rrna pcr product identified a sequence with 100% nucleotide identity to the sequences of mycobacterium lepraemurium, mycobacterium avium, and mycobacterium paratuberculosis in four of ... | 1997 | 9316890 |
| a new agent of mycobacterial lymphadenitis in children: mycobacterium heidelbergense sp. nov. | nontuberculous mycobacterial lymphadenitis presents an increasing clinical problem in immunocompetent young children. a slowly growing, nonphotochromogenic mycobacterium was recovered twice (isolates 2553/91 and 2554/91) from the lymphatic tissue of a child with recurrent cervical lymphadenitis. it could be differentiated biochemically from described mycobacterium species, although it most closely resembled mycobacterium malmoense by thin-layer chromatography and high-performance liquid chromato ... | 1997 | 9399520 |
| inteins in mycobacterial gyra are a taxonomic character. | the a subunit of dna gyrase in mycobacteria is frequently subjected to splicing events as its gene, gyra, harbours an insertion encoding an intein. investigation of a number of different isolates of mycobacterium kansasii, mycobacterium malmoense, mycobacterium marinum, mycobacterium ulcerans and mycobacterium xenopi demonstrated that the presence of gyra inteins is not random but a taxonomic character specific for a given taxon at a species or subspecies level. | 1998 | 9493395 |
| susceptibilities of mycobacterium malmoense determined at the growth optimum ph (ph 6.0). | pulmonary disease caused by mycobacterium malmoense is increasing. conventional in vitro antimicrobial susceptibilities correlate poorly with response to treatment for this organism. radiometrically determined minimum inhibitory concentrations (mics) allow quantitative susceptibility testing for non-tuberculous mycobacteria. the m. avium complex (mac) has been investigated extensively with this approach, and clear interpretative criteria have been established at ph 6.8. however, there has been l ... | 1998 | 9613641 |
| pulmonary disease due to mycobacterium malmoense in british columbia. | mycobacterium malmoense was first described in northern europe and the united kingdom in 1977. since then, reports have appeared with increasing frequency. cases have, however, rarely been reported from the united states, and, until now, none have been reported in canada. this may reflect either true low prevalence of the disease or under-diagnosis by laboratories due to slow growth of the organism. this report describes a case of pulmonary disease caused by m malmoense in a 44-year-old man from ... | 1998 | 9707456 |
| mycobacterium malmoense infections in the united states, january 1993 through june 1995. | mycobacterium malmoense is a nontuberculous mycobacterium rarely encountered in the united states. however, isolations of m. malmoense from 73 patients (11 in 1992, 35 in 1993, and 27 in 1994) were reported to the centers for disease control and prevention. we contacted state mycobacteriology laboratories and health care providers of patients whose m. malmoense isolations were reported from january 1993 through june 1995. to assign disease status for these patients, we used the criteria of the a ... | 1998 | 9770156 |
| mycobacterium malmoense infection. an unusual cause of wrist swelling. | we report a case of non-tuberculous tenosynovitis of the wrist caused by mycobacterium malmoense. the patient presented with a ganglion-like swelling on the flexor aspect of the wrist. the diagnosis was confirmed by fine needle aspiration biopsy. a satisfactory resolution was obtained by antibiotic therapy alone, indicating that radical synovectomy may not be necessary in all cases of m. malmoense infection. | 1998 | 9888690 |
| mycobacterium malmoense-specific nested pcr based on a conserved sequence detected in random amplified polymorphic dna fingerprints. | mycobacterium malmoense is an opportunistic human pathogen of increasing clinical importance. since it is difficult to detect and identify the organism by conventional techniques, it was decided to seek a nucleic acid amplification method specific for m. malmoense. the method was based on detection of a conserved band in random amplified polymorphic dna (rapd) fingerprints of 45 m. malmoense strains. this band was a 1,046-bp product which was proven to be m. malmoense specific in dot blot hybrid ... | 1999 | 10203504 |
| non-tuberculous mycobacterial tenosynovitis: a review. | the clinical characteristics, outcome and treatment of non-tuberculous mycobacterial tenosynovitis are reviewed. from lesions localized in the hand, 10 different species of non-tuberculous mycobacteria have been reported. the most common are mycobacterium marinum and mycobacterium kansasii. other less frequent organisms are mycobacterium avium complex, mycobacterium szulgai, mycobacterium terrae, mycobacterium fortuitum, mycobacterium chelonae, mycobacterium abscessus, mycobacterium malmoense an ... | 1999 | 10482048 |
| acid-alcohol fast bacilli in sputa of hiv-infected patients. | we identified 34 hiv-infected patients with sputum smear positive for acid-alcohol fast bacilli (aafb) to determine any factors predictive of subsequent species identification. there were 20 cases of mycobacterium tuberculosis (mtb), 9 cases of mycobacterium avium-intracellulare (mai), 3 cases of mycobacterium kansasii and one each of mycobacterium malmoense and mycobacterium fortuitum. factors associated with isolation of mai were lower cd4 cell count, a higher incidence of previous aids diagno ... | 1999 | 10492428 |
| mycobacterium malmoense infections in immunocompetent patients. | while mycobacterium malmoense infections were originally restricted to northern europe, there has been an increasing number of reports of cases of infection in other countries. two cases of infections due to mycobacterium malmoense in immunocompetent patients in germany are presented. in both cases a presumptive diagnosis of tuberculosis was established initially. mycobacterium malmoense was cultured after a long incubation period (6-8 weeks). the patients were successfully treated with a triple ... | 1999 | 10517195 |
| vitamin d receptor gene polymorphisms and susceptibility to mycobacterium malmoense pulmonary disease. | polymerase chain reaction using sequence-specific primers was utilized to ascertain the prevalence of 3 polymorphisms of the vitamin d receptor (vdr) gene (foki f/f, apai a/a, and taqi t/t) in 56 patients with mycobacterium malmoense pulmonary disease. when compared with 101 controls, m. malmoense patients displayed an increased prevalence of apa1 a (p=.03; fisher's exact test), taqi t (p=.04), and the at vdr haplotype (p=.04), and they displayed a decreased prevalence of foki f (p=.04). only 4 ... | 2000 | 10837203 |
| non-tuberculous mycobacterial lung infection complicated by chronic necrotising pulmonary aspergillosis. | we report four cases of pulmonary mycobacterial disease (three due to mycobacterium malmoense and one to myco- bacterium avium intracellulare) complicated by the development of chronic necrotising pulmonary aspergillosis. difficulties with treatment and the potential benefits of steroids are discussed. | 2000 | 10899252 |
| in vitro antimycobacterial activities of physalis angulata l. | the hiv-tuberculosis co-infection has caused an impact on tuberculosis epidemiology all over the world and the efficacies of the therapeutic schemes traditionally prescribed in the treatment of tuberculosis, such as isoniazid, rifampicin and pyrazinamide, have decreased due to the appearance of multidrug-resistant m. tuberculosis strains (mdr). this work is part of research on natural antimicrobial agents from plant extracts through bioassay-guided fractionation, by in vitro determination of the ... | 2000 | 10969728 |
| transverse myelopathy and radiculomyelopathy associated with pulmonary atypical mycobacterium infections. | myelopathy is a well recognised but rare association with mycobacterium tuberculosis infection, but has not been described with atypical mycobacteria. we report two cases of disabling myelopathy in association with pulmonary infection by mycobacterium kansasii and mycobacterium malmoense; the myelopathy is presumed to be a para-infectious phenomenon. | 2001 | 11209108 |
| performance assessment of new multiplex probe assay for identification of mycobacteria. | a new dna probe assay (inno lipa mycobacteria; innogenetics, ghent, belgium) for the simultaneous identification, by means of reverse hybridization and line-probe technology, of mycobacterium tuberculosis complex, mycobacterium kansasii, mycobacterium xenopi, mycobacterium gordonae, the species of the mycobacterium avium complex (mac), mycobacterium scrofulaceum, and mycobacterium chelonae was evaluated on a panel of 238 strains including, besides representatives of all the taxa identifiable by ... | 2001 | 11230430 |
| [mycobacterium malmoense cutaneous infection in an immunocompetent patient]. | mycobacterium malmoense is a mycobacterium rarely described as a human pathogen. we report the first case of cutaneous infection in an immunocompetent patient. | 2001 | 11275591 |
| cd1 genotyping of patients with mycobacterium malmoense pulmonary disease. | mycobacterium malmoense is an opportunistic mycobacterium that occasionally causes disease in non-immunosuppressed individuals. as only a few individuals exposed to these organisms actually develop clinical disease, it is possible there is a genetic component to susceptibility. cd1 molecules are capable of presenting antigens from more virulent mycobacteria to t cells; therefore, we were interested in discovering whether recently described polymorphisms in cd1 molecules modulated susceptibility ... | 2001 | 11580851 |
| a hoarse voice: atypical mycobacterial infection of the larynx. | myobacterium malmoense is a non-tuberculous mycobacterium that most commonly causes pulmonary infection, particularly in patients with underlying pulmonary disease or immunodeficiency. we describe a case of mycobacterium malmoense infection of the larynx in a previously well middle-aged woman, which has previously not been reported. the case highlights the importance of considering atypical mycobacterial infection in the differential diagnosis of laryngeal lesions. | 2001 | 11779312 |
| disseminated disease with mycobacterium malmoense in a patient with pneumoconiosis. | | 2001 | 11798264 |
| isolated pituitary granuloma by atypical mycobacterium in a nonimmunosuppressed woman. | a 32-year-old woman presented with a 10-day history of fever (38.0 degrees c), headaches, nausea, vomiting and a 6-month history of diabetes insipidus and amenorrhoea. two months previously she had undergone a surgical drilling of the right mastoid area because of mastoiditis. endocrine investigation showed elevated serum prolactin levels, secondary adrenal and gonadal failure and a normal thyroid function. cranial mri scan revealed a contrast enhancing intrasellar mass (approximately 2 cm) of h ... | 2002 | 11849256 |
| molecular epidemiology of mycobacterium malmoense infections in scotland. | clinical isolates of mycobacterium malmoense collected over 5 years from patients across scotland with a variety of diseases have been characterized by pulsed-field gel electrophoresis (pfge), ribotyping, and 16s ribosomal dna gene sequencing. results indicate that this species harbors little genetic diversity and that the different strain types that were identified by pfge showed no correlation with geographical origin or date of isolation. | 2002 | 11880453 |
| molecular characterization of a spanish isolate of mycobacterium malmoense. | we present the genomic characterization of a spanish isolate of mycobacterium malmoense. identification and molecular characterization of the microorganism were performed using the technique of pcr-restriction fragment length polymorphism analysis (pra) and sequencing of the 16s and the its spacer (16s-23s rdna intergenic spacer region). it was seen that our isolate is very similar to the strain described in sweden, but differs in the sequencing of the its from the isolate in great britain. mole ... | 2002 | 11881896 |
| evidence of the presence of is1245 and is1311 or closely related insertion elements in nontuberculous mycobacteria outside of the mycobacterium avium complex. | a pcr assay based on the simultaneous detection of is1245 and is1311 was developed and used to determine the host range of these insertion elements. specific pcr products were observed in mycobacterium malmoense, mycobacterium scrofulaceum, and mycobacterium nonchromogenicum, indicating that is1245 and is1311 are not limited to the mycobacterium avium complex. | 2002 | 11980981 |