| significance of microorganisms found in throat swabs (author's transl). | | 1976 | 3776 |
| the detection of toxin production by corynebacterium diphtheriae in diagnostic laboratories. | in vitro tests for assessing the toxigenicity of strains of c. diphtheriae using the original agar plate precipitin method of elek are unreliable. at high concentrations of antitoxin (500-1000 u/ml) multiple non-specific precipitin lines occur making interpretation difficult. increased specificity was obtained by diluting the antitoxin but this in turn caused a delay in the appearance of toxin-antitoxin lines. also, the failure of lines to appear on media enriched with unsuitable serum may lead ... | 1976 | 9614 |
| diphtheria toxin. | | 1977 | 20040 |
| letter: recognition of diphtheria. | | 1975 | 46974 |
| letter: avirulent corynebacteria. | | 1975 | 47127 |
| letter: recognition of diphtheria. | | 1975 | 47573 |
| non-toxigenic corynebacterium diphtheriae in a boarding school. | a non-toxigenic strain of corynebacterium diphtheriae var. gravis was isolated from 31 boys during an outbreak of sore throats at a boarding school of 15 staff and 134 pupils. despite the non-toxigenicity of the strain involved, conventional isolation procedures were observed and all boys at the school were treated with antibiotics. restrictions on the school were only relaxed when no further carriers were detected. the rationale of such management of an episode involving a non-toxigenic strain ... | 1975 | 48687 |
| letter: recognition of diphtheria. | | 1975 | 48850 |
| [bacteriological studies of butirosin sulfate, a new aminoglycoside antibiotic (author's transl)]. | | 1975 | 51941 |
| quantitative assay of diphtherial toxin and of immunologically cross-reacting proteins by reversed passive hemagglutination. | a reversed passive hemagglutination (rpha) assay for diptherial toxin has been developed. antitoxic antibodies were isolated from commercially available equine diptherial antitoxin by immunoabsorption using highly purified diphtherial toxin covalently linked to sepharose 4b. formalinized, tanned sheep erythrocytes sensitized with the purified antitoxic antibodies are specifically agglutinated by diphtherial toxin but are not agglutinated by extracellular antigens of corynebacterium diptheriae th ... | 1975 | 54339 |
| [use of fermented and purified diphtheria antitoxin for determination of pathogenicity of corynebacterium diphtheriae]. | | 1976 | 61328 |
| [minor diphtheria epidemic in a cologne children's home (author's transl)]. | between may and july 1972, 12 children aged from 7 to 14 were admitted to the cologne university children's hospital suspected of having diphtheria. in 10 cases the tonsils or pharyngeal cavity were affected. one case of wound diphtheria and one of nasal diphtheria were observed. the clinical suspicion was confirmed in 8 of 12 cases by detection of the pathogen coryne-bacterium diphtheroides mitis. 11 patients were discharged from the hospital after being treated for between 2 to 6 weeks, but 5 ... | 1976 | 64924 |
| response of cultured mammalian cells to the exotoxins of pseudomonas aeruginosa and corynebacterium diphtheriae: differential cytotoxicity. | the sensitivities of 21 mammalian cell lines to the exotoxins of pseudomonas aeruginosa and corynebacterium diphtheriae were measured. each line exhibited 1-4 log differences in sensitivities to the two toxins. no species-specific sensitivities were noted for pseudomonas exotoxin while diphtheria exotoxin was most potent in cells of monkey origin, followed by human and hamster cells. rat- and mouse-derived cell lines were very insensitive to diphtheria exotoxin. the rates of cellular intoxicatio ... | 1977 | 65205 |
| [adsorption of the antigen-reactive cells on the membrane reinforced immunosorbent]. | | 1977 | 72857 |
| an unusual case of cutaneous diphtheria. | | 1978 | 79663 |
| [bacteriocinogenic activity of corynebacterium diphtheriae]. | | 1978 | 81920 |
| polypeptide antibiotic 26a from bacillus subtilis. iv. evaluation of biological in vivo activity. | the studies performed with the antibiotic 26a, which has a close resemblance to bacitracin family polypeptide antibiotics, revealed a prominent therapeutic and protective actions. the antibiotic is characterized by a moderately low toxicity, lack of cytotoxic and cytostatic effects on several tissue cultures, and therapeutic effectiveness in lethal streptococcal infections in mice, and corynebacterial infections in guinea pigs. | 1978 | 86285 |
| value of acid metabolic products in identification of certain corynebacteria. | acid metabolic products of 23 strains of human and animal pathogenic corynebacteria, representing eight different species, were determined by gas chromatography. the results showed that the species examined were metabolically heterogeneous and could be presumptively identified based on the acid products produced. corynebacterium equi did not produce any acids; c. renale produced lactate; and c. pyogenes produced major amounts of lactate, variable amounts of acetate, and minor amounts of succinat ... | 1978 | 96126 |
| rapid determination of corynebacterium diphtheriae toxigenicity by counterimmunoelectrophoresis. | a method for detecting toxin production in corynebacterium diphtheriae cultures by counterimmunoelectrophoresis is described. precipitin lines were observed in toxigenic strains in 30 min. | 1978 | 96129 |
| isolation of the l-phase variant from toxigenic corynebacterium diphtheriae c7(beta). | the l-phase variant was isolated from lysogenic strain c7(beta) of corynebacterium diphtheriae by the penicillin disk tecnnique on an agar medium containing 3.7% brain heart infusion, 3% nacl, 1.25% grycine, 1% noble agar, and 10% horse serum. the l-phase formed a "fried egg" colony; it was resistant to antibiotics that inhibit biosynthesis of bacterial cell walls but was susceptible to antibiotics that act on the protein-synthesizing system. after several transfers of the l-phase initially isol ... | 1978 | 97222 |
| role of exotoxins in bacterial pathogenicity. | | 1978 | 97256 |
| [prospects for the use of blood substitutes made in the ussr with the expired date of validity]. | as revealed, blood substitutes--aminopeptide, caseine hydrolysate, and hydrolysine with the expired date of validity could be used as the basis of nutrient media for the cultivation of bacteria. bacterial growth proved to be the optimum in addition to the blood substitutes of a 0.25--0.5% of yeast extract. | 1978 | 97885 |
| evidence that the regulation of diphtheria toxin production is directed at the level of transcription. | it has been known for several decades that iron inhibits the production of diphtheria toxin by corynebacterium diphtheriae by preventing expression at maximal levels. we examined the inhibition kinetics of toxin production after the addition of either iron or rifampin to iron-limited cultures of c7 (betatox+). iron-mediated inhibition of toxin production was found to be linear within the range of 16 nm to 16 micron. the inhibition kinetics following the addition of iron or rifampin was almost id ... | 1978 | 98519 |
| vaccination and hodgkin's disease. | | 1978 | 99187 |
| [serologic relationship between toxigenic and nontoxigenic c. diphtheriae with reference to the cultural variant gravis]. | | 1978 | 99927 |
| [epiedmiologic significance of the distribution of corynephages in different collectives]. | corynephage distribution was studied in the nasopharyngeal washings of 252 persons infected with c. diphtheriae of gravis type, toxigenic (21 patients and 147 carriers) and non-toxigenic ones (84 carriers), and in 468 uninfected persons in collective bodies under different epidemic conditions. corynephages were isolated from the nasopharyngeal washings only in persons infected with toxigenic c. diphtheriae--in 4 (of 21) patients, and in 21% (of 147) carriers. phages tox+ (4--6.2%) were revealed ... | 1978 | 99930 |
| control of corynebacteriophage reproduction by heteroimmune repression. | corynebacteriophages beta and gamma are closely related but heteroimmune; hence, gamma reproduces in c7(beta). a series of gamma mutants, designated gamma-bin (beta-inhibited), has been isolated. they reproduce in only 2 to 14% of infected c7(beta) cells, and, as a result, plaque with an efficiency of 10(-4) to 10(-5) on this strain. the proportion of c7(beta) cells in which gamma-bin phage can replicate is increased to 30 to 80% when immunity is lifted by uv induction of c7(beta) or by heat ind ... | 1978 | 100610 |
| [comparative study of the bactericidal action of the body of ornithodoros papillipes ticks]. | experiments in vivo have shown that the ticks of ornithodoros papillipes inhibit both gram-positive and gram-negative bacteria. on gram-positive microorganisms most sensitive to bactericidal effect of ticks have turned to be micrococci, staphylococci, streptococci and bacteria of diphtheria, of gram-negative ones--bacillus coli. of gram-positive microorganisms less sensitive were listeria, of gram-negative ones--salmonellae, agents of tularemia and pseudotuberculosis. at the infection with bacte ... | 1978 | 100756 |
| isolation, structural studies and chemical synthesis of a 'palmitone lipid' from corynebacterium diphtheriae. | the isolation of a 'palmitone lipid' from corynebacterium diphtheriae is described. the use of a temporary hydrophobic protecting group allows the obtaining of the lipid in free and pure form. structural studies by chemical degradation and mass spectrometry allow one to propose structure ic for this compound, namely 6-(2-tetradecyl 3-keto octadecanoyl)-alpha-d-trehalose. this structure was confirmed by chemical synthesis. | 1978 | 102431 |
| quantitative studies on competitive activities of skin bacteria growing on solid media. | earlier quantitative investigations of antagonism between skin bacteria were based on the use of liquid cultures, but a more realistic model has now been devised, based on the use of the surfaces of solid media. pure or mixed inocula were spread evenly over suitable agar media in petri dishes marked out with a standard grid. growth curves were constructed from viable counts of the surface bacteria after they had been removed from excised squares of the agar media and dispersed. the method was hi ... | 1978 | 102799 |
| [participation of bacterial neuraminidases in the development of disease]. | | 1978 | 103344 |
| [a leg ulcer from the tropics caused by corynebacterium diphtheriae?]. | | 1979 | 104183 |
| [use of microbial cells of corynebacterium diphtheriae for preparing a nutrient medium]. | nutrient media prepared on the basis of microbial cells (corynebacteria diphtheriae) proved to be no less nutrient in comparison with conventional media prepared on the full-value food products. use of diphtheria bacilli (by-products of diphtheria toxoid production) as the basis for nutrient media permitted to use up to 30% less food products for this purpose. | 1979 | 105520 |
| three variants of corynebacterium diphtheriae subsp. mitis (belfanti) isolated from a throat specimen. | three variants of a corynebacterium diphtheriae subsp. mitis strain belfanti, two toxigenic (phage types 7 and 11) and one nontoxigenic (phage type 7), were simultaneously isolated from the throat of an adult. | 1978 | 106070 |
| [testing of a system of unidirectional serologic reactions for detection of diphtheria antigens and antibodies]. | | 1979 | 106599 |
| [heteromorphism of corynebacteria. i. macrocells]. | a possibility of formation of macrocells (mac) of diphtheria bacilli was expressed to a different degree; the extreme expression are giant and supergiant forms. giant forms with section dimension of 3--5micron retained their capacity to disorderly septation with the resultant formation of microcells (mic). apparently some of the septa were not realized. supergiant forms were revealed as a layer and its transverse section. the length of the latter reached 30micron with the transverse section of 2 ... | 1978 | 106605 |
| structural determination of 'cord factor' from a corynebacterium diphtheriae strain by a combination of mass spectral ionization methods: field desorption cesium cationization and electron impact mass spectrometry studies. | the composition and structure of a preparation of 'cord factor' (di-beta-hydroxy acyl trehaloses) from corynebacterium diphtheriae have been determined by a combination mass spectral ionization methods. the methods were tested by means of synthetic 6,6'-dicorynomycolate of alpha-d-trehalose prior to their use on natural products. the determination of the molecular weight of the components and the estimation of their relative abundance in the natural mixture were made by field desorption mass spe ... | 1978 | 106902 |
| ige synthesis in man. ii. comparison of tetanus and diphtheria ige antibody in allergic and nonallergic children. | | 1979 | 107210 |
| bactericidal effects of anesthetics. | | 1979 | 107831 |
| a modified gel-diffusion technique for testing toxigenicity of corynebacterium diphtheriae. | | 1978 | 108219 |
| epidemiologic studies among amerindian populations of amazônia. i. pyoderma: prevalence and associated pathogens. | pyoderma was studied among a representative sample of the residents of four remote amerindian villages, amazonas state, brazil, during july-august 1976. the overall prevalence among the 775 inhabitants examined was 11%, with little intervillage variation. when the attack rates for the entire sample population were calculated by 5-year age intervals, the 0- to 4-year-olds had the highest rate, 31%. the highest prevalence, 38%, was found among 3-year-olds. attack rates were not apparently related ... | 1979 | 110164 |
| [antibacterial immunity in diphtheria. experimental research]. | a number of 700 guinea pigs were immunized by parenteral route with non-toxigenic corynebacterium diphtheriae strains, then inoculated with various doses of homologous and heterologous toxigenic c. diphitheriae strains. the results showed that non-toxigenic c. diphtheriae strains confer a certain degree of protection when the challenge is done with homologous toxigenous strains, especially when not more than 500 million germs/ml are used for the challenge dose. this suggests that the carriage of ... | 1979 | 111333 |
| [heteromorphism of the corynebacteria. iii. d- (dark) and c- (clear) cell types and multiseptate specimens]. | a population of corynebacterium diphtheriae may consist of cells with accented (osmiophilic) cytoplasm (cells of the "dark" type, or d type) and cells with cytoplasm having no pronounced osmiophilic properties (cells of the "clear" type, or c type). the divergence of the population into cells of the d and c types occurs at the stage of cell division, the original mother cell being able to divide into 2 or more individual cells belonging to different types (elongated multiseptate cells). at the s ... | 1979 | 111440 |
| occurrence of 3-oxo-acyl groups in the 6,6'-diesters of alpha-d-trehalose. new glycolipids related to cord factor from corynebacterium diphtheriae. | | 1979 | 111936 |
| [a tropical ulcus cruris caused by corynebacterium diphtheriae?]. | | 1979 | 112483 |
| [interrelationship of toxin formation with proteolytic enzyme synthesis in the process of cultivating diptheria microorganisms]. | for the first time the synthesis of proteolytic enzymes by corynebacterium diphtheriae has been shown to precede the process of toxin formation. the process of controlling the proteolytic activity of enzymes seems to be a suitable basis for the evaluation of toxin formation in mathematically planned experiments with strictly controlled tasks. | 1979 | 112807 |
| [appearance in domestic animals of corynebacterium diphtheriae and other corynebacterium strains pathogenic for man]. | | 1979 | 113847 |
| activity of penicillin, erythromycin, and cephalosporins against isolates of corynebacterium diphtheriae from cutaneous lesions. | | 1979 | 114513 |
| isolation of a cured strain from corynebacterium diphtheriae pw8. | a nonlysogenic, non-toxinogenic strain was isolated from the pw8 strain of c. diphtheriae by two-step ultraviolet induction. this strain was lysed by phages derived from the pw8 strain but not by beta phages from the c7(beta) strain. when this cured strain was lysogenized with phages from the pw8 strain, toxin production by the resulting lysogens was about a half or a quarter of that of the parent strain pw8. | 1979 | 115787 |
| characterization of a screening test for diphtherial toxin antigen produced by individual plaques of corynebacteriophages. | a passive immune hemolysis assay has been developed to detect diphtherial toxin produced in individual plaques of tox+ corynebacteriophages. this assay permits rapid screening of large numbers of corynebacteriophages for their ability to code for diphtherial toxin or related antigens. the specificity of the assay and its potential usefulness for genetic studies of toxinogenesis have been demonstrated with well-characterized tox+ and tox- laboratory strains of corynebacteriophages. | 1979 | 115898 |
| [effect of the degree of culture aeration on diphtheria toxin production and growth of 3 variants of corynebacterium diphtheriae pw 8]. | | 1979 | 116098 |
| erythromycin and clindamycin resistance in corynebacterium diphtheriae from skin lesions. | erythromycin- and clindamycin-resistant corynebacterium diphtheriae isolates were recovered from skin lesions. resistance to erythromycin and clindamycin was induced by a subinhibitory concentration (0.03 microgram/ml) of erythromycin. clindamycin (0.07 microgram/ml) was a more effective inducer of its own resistance than of erythromycin resistance. erythromycin-inducible cross-resistance to vernamycin b alpha was demonstrated in disk diffusion tests. | 1979 | 117748 |
| non-toxigenic corynebacterium diphtheriae causing subacute bacterial endocarditis: case report. | this is the case report of a 13-yr-old european child from a boarding school at herberton, on the atherton tableland, who developed subacute bacterial endocarditis, with 6 blood cultures at different times growing a non-toxigenic strain of corynebacterium diphtheriae. | 1979 | 118422 |
| effect of metal ions on diphtheria toxin production. | the effect of several metal ions on the production of diphtheria toxin was tested. by using the gel immunodiffusion system for detecting toxin, a wide range of metal ion concentrations was conveniently surveyed. five divalent cations, fe2+, cu2+, co2+, ni2+, and mn2+ inhibited toxin production within a range of concentrations that did not inhibit growth of the producing strain. growth and toxin production were inhibited at identical concentrations by both cd2+ and zn2+, whereas al3+ and sr2+ aff ... | 1979 | 118927 |
| studies on the pw 8 phage of the park williams no. 8 strain of c. diphtheriae and on species within corynebacterium genus capable of producing diphtherial toxin. | | 1978 | 120166 |
| prevalence of corynebacterium diphtheriae in pyoderma and other skin lesions. | | 1979 | 120849 |
| method for quantitating sensitivity to a staphylococcal bacteriocin. | a convenient method for quantitating the sensitivity of large numbers of bacterial strains (presently corynebacterium diphtheriae) to a staphylococcus aureus phage type 71 bacteriocin is described. | 1979 | 121117 |
| [septic arthritis due to a nontoxigenic diphtheria bacillus]. | septic arthritis of the hip in a 2 year old child is described. a nontoxigenic diphtheria bacillus was isolated in large numbers from the articular fluid. the same organism was isolated from excoriated skin lesions of the toes. the bacteriology, epidemiology and pathology of the infection are discussed. | 1979 | 122141 |
| fulminant diphtheritic mitral valve endocarditis. | fulminant endocarditis affecting the mitral valve in an 11-year-old boy was caused by a nontoxogenic strain of corynebacterium diphtheriae. | 1976 | 133640 |
| differential chemical protection of mammalian cells from the exotoxins of corynebacterium diphtheriae and pseudomonas aeruginosa. | many drugs or chemicals had markedly different effects on the cytotoxicity induced by pseudomonas aeruginosa exotoxin a (pe) or corynebacterium diphtheriae exotoxin (de). the glycolytic inhibitor naf protected cells from de but potentiated the cytotoxicity of pe. another energy inhibitor, salicylic acid, also protected cells from de but had no effect with pe. colchicine and colcemid did not affect the cytotoxicity of either toxin. cytochalasin b exhibited a modest protection from de but no effec ... | 1977 | 141424 |
| [interrelationship between toxigenic and non-toxigenic diphtheria microbes in the epidemic process]. | a study of the circulation of toxigenic and nontoxigenic diphtheria bacilli was carried out in several carrier state foci under conditions of a natural course of the epidemic process. there were 2623 persons under observation. a total of 32158 analyses were carried out, and 2271 strains were isolated and studied. no formation of the toxigenic variants of diphtheria bacillus as a result of phage conversion was revealed in the foci of carrier state despite the wide spread in them of nontoxigenic l ... | 1977 | 143172 |
| [research on anti-diphtheria immunization in the city of bucharest]. | biological, sero-epidemiological and bacteriological investigations, carried out in the town of bucharest for evaluating the present diphtheria vaccination programme showed: -- high anatoxin titers, exceeding the titer considered as protective, in the vaccinates ; -- a concentration of the level of the titers of 1--4 au/ml, in over 62% of the subjects, which means that the protective titer was exceeded 33 to lucru: -- negative schick reaction, in the mean 95.06%, in the subjects examined during ... | 1977 | 143711 |
| epidemiological features of skin diphtheria infection in rangoon, burma. | a survey for skin diphtheria was carried out on 493 patients with skin lesions who were attending veneral diseases & dermatology clinic in rangoon in 1971. 63.8% of the patients had c. diphtheriae in their skin lesions. all ages and both sexes were equally affected. skin lesions yielding c. diphtheriae on culture were indistinguishable from those associated with other bacteria including ecthyma, pyoderma and secondarily infected with parasitic infections. out of 108 strains tested 18.5% were fou ... | 1978 | 151920 |
| diphtheria toxin: mode of action and structure. | | 1975 | 164179 |
| the action of vibrio cholerae and corynebacterium diphtheriae neuraminidases on the sendai virus receptor of human erythrocytes. | studies of the sendai virus haemagglutinin receptor on the human erythrocyte surface have confirmed that it involves 2 leads to 3 linked sialic acid. because the primary specificity of vibrio cholerae neuraminidase is for this linkage, it is able to compete with the virus for the receptor, to which it adsorbs strongly at low temperatures. corynebacterium diphtheriae neuraminidase, whose principal specificity is for a sialic acid linkage other than 2 leads to 3, does not easily remove sendai viru ... | 1975 | 168311 |
| bacteria in hip surgery. a study of routine aerobic and anaerobic cultivation from skin and closed suction wound drains. | one hundred and seven patients with closed suction wound drains after hip surgery were investigated with regard to bacteria in the drain. in one-third of the cases bacterial contamination of the wound was found. in more than half the total number of cases the bacteria in the wound were not identical with those found on the skin, either pre- or post-operatively. anaerobe bacteria occurred only in one case. penicillin administration considerably reduced the frequency of positive cultures. these fi ... | 1976 | 181944 |
| antibody responses in normal infants and in infants receiving chemotherapy for congenital neuroblastoma. | three infants with congenital neuroblastoma received a primary series of diptheria-pertassis-tetanus (dpt) immunizations during and after courses of chemotherapy with immunosuppressive medications. serum igg, iga and igm levels and antidiphthria and antitetanus antibody responses were measured and compared with those of normal infants of similar age. protective levels of antibody were achieved by the study patients as well as by the control group. these results support the view that children wit ... | 1977 | 198094 |
| [comparative study of the reactogenicity of dtp vaccine, dt and modified dt anatoxins in revaccinating 6-year-old children]. | | 1978 | 208331 |
| isolation and characterization of extragenic suppressor strains of corynebacterium diphtheriae. | the isolation and characterization of two different nonsense suppressor strains of corynebacterium diphtheriae c7 sup+(-)tox- are described. appropriate lysogens of these strains with corynephage beta, carrying known class ii tox premature polypeptide chain termination mutations [c7sup-1(betatox-30) and c7sup-2(betatox-45)], each produce a 62,000-dalton polypeptide with nicotinamide adenine dinucleotide: elongation factor-2 adenosine diphosphate ribosyltransferase activity in addition to a chain ... | 1978 | 214419 |
| [changes in the antibacterial effects of organs and tissues of ornithodoros papillipes birula ticks]. | | 1975 | 234572 |
| the bacteriological ecosystem of the skin of children in an african tropical envirovment (tanzania). | using a standardized method for sampling, the aerobic microbial flora of the skin of ninety-five children in dar es salaam, tanzania, was studied qualitatively and quantitatively. the subjects comprised three groups; group a, thirty-seven normal infants (below the age of 1 year); group b, twenty-nine infants with various bacterial skin lesions; and group c, twenty-nine nursery school children between 4-5 and 7 years. the following observations were made: (i) the quantitative results indicated; ( ... | 1975 | 239739 |
| prosthetic valve endocarditis by opportunistic pathogens. | the incidence of endocarditis produced by the so-called "opportunists" as a complication of prosthetic valve surgery is progressively increasing in frequency and gradually transforming the clinical picture habitually associated with this disease. we report six cases of endocarditis produced by opportunistic microorganisms (two cases by candida, and the remaining by serratia, actinobacillus, acinetobacter calcoaceticus, and bacteroides fragilis, and by corynebacterium diphtheriae) in four male an ... | 1977 | 319774 |
| nonspecific immunostimulant activities of synthetic trehalose-6,6'-diesters (lower homologs of cord factor). | mycobacterial cord factors (6,6'-diesters of trehalose with mycolic acids ranging from c80 to c90) have been shown to protect mice effectively against infection with klebsiella pneumoniae or with listeria monocytogenes. our present findings indicate that the low-molecular-weight cord factor of corynebacterium diphtheriae (with corynomycolic acids ranging from c28 pto c36) is equally active. moreover, its synthetic analog (with synthetic c32 mycolic acid) has the same activity. two lower syntheti ... | 1978 | 352926 |
| fatty and mycolic acid composition of bacterionema matruchotii and related organisms. | whole-organism methoanolysates of bacterionemae contained mycolic acids in addition to other long-chain fatty acids. these mycolic acids were similar in general structure and overall size to those found in strains of corynebacterium diphtheriae and corynebacterium xerosis. the long-chain fatty acids of bacterionemae, mainly straight-chain saturated and unsaturated acids, were similar to those of certain coryneform bacteria including c. diphtheriae. on the basis of these lipid data, and results o ... | 1977 | 401865 |
| serum effects on the response of mammalian cells to the exotoxins of pseudomonas aeruginosa and corynebacterium diphtheriae. | the response of mammalian cells to pseudomonas and diphtheria exotoxins was studied. a method was developed whereby the sensitivity of cells to these two toxins could be quantitated. the method is versatile and can be used to study the effects of toxins on many cellular metabolic or transport processes. the type of serum used in the culture medium significantly influenced the response of cells to the toxins. calf, horse, and human sera protected cells while fetal calf serum did not. precipitatio ... | 1977 | 402176 |
| [diphtheria epidemic in eastern switzerland in 1974]. | a diphtheria epidemic in the eastern part of switzerland in 1974 and the measures which were taken for its management and eradication are described. in particular it is pointed out that at present diphtheria displays atypical clinical symptoms in europe, a fact that renders the diagnosis very difficult in many cases. therefore, it is important to perform a throat swab in every patient with suspected diphtheria; it is also necessary to explicitly require a search for c. diphtheriae. the early rec ... | 1977 | 403601 |
| enumeration and identification of human leukemic lymphocytes by their natural binding of bacteria. | the recently described property of bacteria to bind to human lymphocytes was used to distinguish between normal and chronic leukemic lymphocyte (cll) populations. strains of the following bacteria were used in this study: arizona hinshawii, escherichia coli strains 1 and 2, bacillus globigii, brucella melitensis, corynebacterium diphtheriae strains 1 and 2, corynebacterium xerosis, sarcina lutea, staphylococcus aureus, and staphylococcus epidermidis. for identification of immunoglobulin-bearing ... | 1977 | 404035 |
| [diphtheria]. | | 1977 | 404227 |
| mutations of corynephage beta that affect the yield of diphtheria toxin. | | 1977 | 404756 |
| [molecular weight of bacterial toxins]. | | 1977 | 404803 |
| [role of oxygen in controlling the process of c. diphtheriae cultivation]. | | 1977 | 404809 |
| differentiation of streptococci from diphtheroids. | | 1977 | 405070 |
| identification of five human lymphocyte subpopulations by their differential binding of various strains of bacteria. | | 1977 | 405106 |
| studies on cutaneous diphtheria in and around delhi. | | 1977 | 405317 |
| diphtheroid osteomyelitis. | isolates of either corynebacterium diphtheriae or propionibacterium acnes from osteomyelitis are not necessarily contaminants, as shown by the cases of three patients who had bone and joint infections in which these organisms were pathogenic (one in pure culture and two in mixed cultures). previous operation or other factors that compromise host resistance create the setting for these opportunistic organisms. penicillin with or without streptomycin is the treatment of choice, but if penicillin o ... | 1977 | 405396 |
| [effectiveness of a hemolyzed preparation for isolation of pure cultures of diphtheria bacilli]. | | 1977 | 405555 |
| [relationship between the culture medium and the fatty acid composition of diphtheria and non-pathogenic corynebacteria]. | the gasochromatic method was applied to the study of the cellular fatty acids composition in diphtheria and nonpathogenic corynebacteria (diphtheroids and psendo diptheria bacillus). marked differences in the content of unsaturated fatty acids were revealed in them. thus, palmito leic acid served the preponderant unsaturated fatty acid in corynebacteria diphtheriae, and unsaturated fatty acids with 18 carbon atoms (octadeconoic and linoleic)--in nonpathogenic corynebacteria. the mentioned change ... | 1977 | 405825 |
| toxin production by strain c7 (beta), its mutants and their l-phase variants of corynebacterium diphtheriae. | | 1977 | 406436 |
| heat-inducible mutants of corynebacteriophage. | heat-inducible mutants of temperate cornebacteriophage beta and gamma, called temperature-sensitive repression (tsr) mutants, were isolated and characterized. lysogens carrying these mutants were induced at 38 degrees c, produced a normal or slightly increased yield of phage, and underwent extensive lysis at this temperature. in some cases mutation to heat inducibility had altered the uv inducibility of the phage, the changes ranging from loss to enhancement of this trait. complementation tests ... | 1977 | 408516 |
| bacteriophage production by doubly lysogenic corynebacterium diphtheriae. | parental and recombinant phage production by tandem, double lysogens of corynebacterium diphtheriae was studied in strains in which the coupling of prophage markers and the order of prophage was established. the results from studies of mass lysates and single bursts showed that the recombinant class of phage, designated r1, was predominant in uv-induced lysates followed by the parental, p1 class and to a lesser extent the p2 and r2 classes. single bursts of uv-treated cells contained phage from ... | 1977 | 408517 |
| carriage of non-toxigenic corynebacterium diphtheriae by australian aboriginals. | a survey of 200 aboriginals in western australia revealed five carriers of non-toxogenic corynebacterium diphtheriae; four of these were variety mitis and one was variety gravis. | 1977 | 408595 |
| biochemical characters to differentiate strains of corynebacterium diphtheriae, c. xerosis and c. hofmannii. | | 1977 | 409666 |
| isolation from corynebacterium diphtheriae c7(beta) of bacterial mutants that produce toxin in medium with excess iron. | five mutants that produce toxin in medium with excess iron were isolated from strain c7(beta). the iron content of bacteria grown on this medium was considerably higher than that of c7(beta) cells grown in medium containing the minimum amount of iron needed to inhibit toxin production. when the nonlysogenic, nontoxinogenic strain c7(-) was lysogenized with phages from each of the mutants, toxin production by all of the resulting lysogens, like that by parent strain c7(beta), ceased upon iron add ... | 1977 | 409685 |
| bacteriophage typing of corynebacterium diphtheriae. | bacteriophage types of over 3,000 strains of corynebacterium diphtheriae isolated in canada have been determined. the typing scheme used involved the use of nine phages. results indicated that phage types correlate with biotypes to a large degree. corynecin types were also determined for a limited number of cultures, and results indicated that the indicator strains presently available are unsuitable for the typing of c. diphtheriae strains isolated in north america. the distribution of phage typ ... | 1977 | 410896 |
| [extracellular material of some representatives of the genus corynebacterium (the electron microscopic aspect)]. | at the active developmental phases (up to 2 days) cells of toxigenic and nontoxigenic corynebacteria form extracellular vesicle-like material of two types which can be revealed both on whole cells set off by metal and stained negatively, and in ultrathin sections. extracellular material of the first type is a derivative of an extensive membranous coat of corynebacteria and is formed as a result of its fragmentation. vesicles of this type are devoid of electron microscope-dense content, have no t ... | 1977 | 411293 |
| [preliminary subdivision of corynebacteria related to c. diphtheriae var. gravis that ferment starch]. | | 1977 | 411294 |
| inhibition of diptheroid esterase by micrococcus luteus. | micrococcus luteus produced a diffusible, esterase inhibitory factor (eif) which inhibited the activity of cutaneous diphtheroid esterases on tween 80-cacl2 agar media. esterases of staphylococcus, micrococcus, bacillus, and serratia were not susceptible. eif did not appear to combine with the substrate or to prevent enzyme synthesis; it was unable to reverse the precipitation of calcium oleate. the composition of the medium, especially peptones, influenced the production of eif. eif was synthes ... | 1977 | 411559 |
| studies on the fine structure of corynebacterium diphtheriae-granules. | the seemingly homogeneous metachromatic and electron-scattering granules of corynebacterium diphtheriae have two structural components as revealed under conditions of low beam load and by use of ribonuclease. they contain high percentages of p and ca. findings point to participation of ribosomes and intracytoplasmic membranes in the formation of the granules. | 1977 | 412349 |
| [the species c. diphtheriae]. | corynebacteria (c. diphtheriae var. gravis, mitis, minimus, intermedius, c. belfanti, c. ovis, c. ulceraus) producing diphtheria toxin are found as variants sharply differing from one another morphologically (from long branching rods to coccobacilli), culturally, biochemically and by other signs. the toxin synthesis in them was determined by genetically heterogeneous prophages tox+; tox+ virus exchange is possible between the corynebacteria. since production of specific toxin, the cardinal sign ... | 1977 | 413292 |
| diphtheria corneal ulcers. | an adult with cutaneous diphtheria was admitted with bilateral purulent conjunctivitis and a perforated eye with most of the cornea absent due to corynebacterium diphtheriae. at the time of admission of grayish patch of corneal epithelium was noted in the other eye, and in the next 24 hours there developed a large corneal perforation with dissolution of much of the cornea. involvement of the external eye in diphtheria is rare but it is usually associated with cutaneous forms of the disease. cuta ... | 1978 | 414704 |