| relationship between oxygen sensitivity and oxygen metabolism of bifidobacterium species. | bifidobacteria, which are obligate anaerobes, were studied to determine the relationship between their sensitivity to oxygen and oxygen metabolism. among the four species tested, bifidobacterium infantis, bifidobacterium breve, and bifidobacterium longum differed from bifidobacterium adolescentis in sensitivity to oxygen. the former three species showed marked growth under conditions of partial aeration, whereas the growth of b. adolescentis was suppressed by low concentrations of oxygen. bifido ... | 1992 | 1474198 |
| [the influence of cefdinir on the intestinal bacterial flora]. | the influence of cefdinir (cfdn), a new oral cephalosporin, on the intestinal bacterial flora was studied in tetra-contaminated mice and in pediatric patients. cfdn in fine granules was administered at a dose of 10 mg/kg once a day for 5 consecutive days to mice contaminated with 4 different species of organism: escherichia coli, enterococcus faecalis, bacteroides fragilis and bifidobacterium breve. no remarkable changes were observed in the fecal viable cell counts except that decreases in e. c ... | 1992 | 1495195 |
| [influence of cefodizime on intestinal bacterial flora]. | effects of cefodizime (cdzm), a new injectable cephem antibiotic, on the intestinal bacterial flora were studied in tetra-contaminated mice and in pediatric patients. cdzm was intramuscularly administered at a dose of 100 mg/kg once a day for 5 consecutive days to mice contaminated with 4 different species of organisms: escherichia coli, enterococcus faecalis, bacteroides fragilis and bifidobacterium breve. for 3 species except e. faecalis, bacterial populations in feces were markedly reduced af ... | 1991 | 1880920 |
| structure of macroamphiphiles from several bifidobacterium strains. | lipoteichoic acid-like substances, macroamphiphiles, were isolated from cell homogenates of bifidobacterium bifidum yit 4007 and yit 4013, bifidobacterium breve yit 4010 and yit 4014, and bifidobacterium longum yit 4021 by phenol extraction followed by nuclease digestion, gel chromatography, ion-exchange chromatography, and hydrophobic interaction chromatography. the macroamphiphile preparations from these five strains contained d-glucose, d-galactose, glycerol, phosphorus, l-alanine, and fatty ... | 1990 | 2298702 |
| growth promotion of bifidobacterium species by whey and casein fractions from human and bovine milk. | an in vitro assay was used to study the growth-promotional activity of human milk (hm), cow's milk (cm), and whey and casein fractions of hm and cm for five strains of bifidobacterium species isolated originally from stools of human infants. whey- and casein-predominant cm-based infant formulas were studied as well. when compared on an equivalent protein basis, the growth promotion activity of hm was greater than that of cm for bifidobacterium bifidum serovar pennsylvanicus and bifidobacterium l ... | 1990 | 2312674 |
| [the influence of cefpodoxime proxetil on the intestinal bacterial flora]. | the influence of cefpodoxime proxetil (cpdx-pr, cs-807), a new oral cephalosporin, on the intestinal bacterial flora was studied in tetra-contaminated mice and in pediatric patients. cpdx-pr dry syrup was administered at a dose of 10 mg/kg once a day for 5 consecutive days to mice contaminated with 4 different species of bacteria: escherichia coli, enterococcus faecalis, bacteroides fragilis and bifidobacterium breve. no notable changes were observed in fecal viable cell counts except that sligh ... | 1989 | 2681865 |
| [pharmacokinetic and bacteriological studies on sulbactam/ampicillin in the field of pediatrics]. | pharmacokinetic and bacteriological studies were carried out on sulbactam/ampicillin (sbt/abpc) in the field of pediatrics. the results obtained are summarized as follows: 1. a total of 248 clinical isolates were employed to determine minimum inhibitory concentrations (mic) of sbt/abpc against various bacterial species. sbt/abpc showed stronger antibacterial activity against gram-positive organisms than against gram-negative rods. 2. the peak serum level of abpc was about twice as high as that o ... | 1989 | 2746843 |
| [the influence of cefteram pivoxil on the intestinal bacterial flora]. | the influence of cefteram pivoxil (cftm-pi), a new oral cephalosporin, on the intestinal bacterial flora was studied in tetra-contaminated mice and in pediatric patients. cftm-pi in fine granular form was administered at a dose of 10 mg/kg once a day for 5 consecutive days to mice contaminated with 4 different species of organisms: escherichia coli, enterococcus faecalis, bacteroides fragilis and bifidobacterium breve. no remarkable change was observed in the fecal viable cell count except that ... | 1989 | 2810740 |
| immunogenicity of bifidobacterium breve and change in antibody production in peyer's patches after oral administration. | immunogenicity in the intestine of bifidobacterium breve, included in fermented milk, was compared with that of bacteroides thetaiotaomicron, also predominant in human intestine. in vivo, serum antibody to b. breve was detected first in mice fed the organism for 33 d; antibody decreased in mice fed these for more than 33 d. serum antibody to bact. thetaiotaomicron was detected in mice fed the organism for 7 d and was maintained at the same level in mice fed these for more than 7 d. from in vitro ... | 1989 | 2925954 |
| the effects of bifidobacterium breve administration on campylobacter enteritis. | | 1987 | 3144842 |
| [influence of sultamicillin on intestinal bacterial flora]. | effects of sultamicillin (sbtpc) fine granules, a new oral beta-lactam antibiotic, on the intestinal bacterial flora were studied in tetra-contaminated mice and in pediatric patients. sbtpc was administered at a dose of 100 mg/kg once a day for 5 consecutive days to mice contaminated with 4 different species of organisms: escherichia coli, enterococcus faecalis, bacteroides fragilis and bifidobacterium breve. in all of the 4 species, bacterial populations in feces were markedly reduced on days 4 ... | 1988 | 3266882 |
| [influence of cefroxadine dry syrup on intestinal bacterial flora]. | influence of cefroxadine (cxd) dry syrup on intestinal bacterial flora was studied in mice infected with 4 species of bacteria, namely, escherichia coli, enterococcus faecalis, bacteroides fragilis and bifidobacterium breve, and in pediatric patients having infections in the respiratory tract and cutaneous/soft tissues. the results were summarized as follows: cxd dry syrup was administered for 5 consecutive days to mice infected with the 4 species. no considerable changes were observed in levels ... | 1986 | 3540337 |
| a new site-specific endonuclease bbei from bifidobacterium breve. | | 1982 | 6282709 |
| the intestinal microflora of infants: composition of fecal flora in breast-fed and bottle-fed infants. | the fecal flora of 35 breast-fed and 35 bottle-fed babies was determined. bifidobacteria were the predominant fecal bacteria in both groups. conversely, the counts of most of the other bacteria, such as bacteroides, eubacteria, peptococci, veillonella, clostridia, enterobacteria, streptococci, and bacilli in the bottle-fed group were significantly higher than those in the breast-fed group. the frequencies of occurrence of lecithinase positive clostridia, clostridia-others, pseudomonas and bacill ... | 1984 | 6513816 |
| properties of the biotin transport system in bifidobacterium breve n4. | binding of biotin to resting cells of bifidobacterium breve n4, which grew in a biotin-deficient medium, was independent of ph from 1 to 9 and of temperature below 50 c. it was not inhibited by metabolic inhibitors including sulfhydryl reagents, but it was inhibited by treatment with 80% ethanol or 5% trichloroacetic acid. it was also competitively inhibited by biotin-sulfone, but not by tetrahydrothiophene nor dethiobiotin. the binding constant was calculated to be 3.3 x 10(8) m--1. the amount ... | 1981 | 7278709 |
| augmentation of anti-influenza virus hemagglutinin antibody production by peyer's patch cells with bifidobacterium breve yit4064. | bifidobacterium breve yit4064 was tested an an adjuvant for oral influenza vaccine by the murine peyer's patch cell culture method. the organism augmented production of anti-influenza virus hemagglutinin immunoglobulin a antibody by peyer's patch cells in response to addition of hemagglutinin. these antibodies may be disseminated to the respiratory mucosal tissue and prevent influenza virus infection. | 1994 | 7496955 |
| passive protection against rotavirus-induced diarrhea of mouse pups born to and nursed by dams fed bifidobacterium breve yit4064. | mouse pups born to and nursed by dams fed bifidobacterium breve yit4064 and immunized orally with rotavirus were more strongly protected against rotavirus-induced diarrhea than those born to and nursed by dams immunized with rotavirus only. the level of antirotavirus iga in milk of dams fed b. breve yit4064 and immunized orally with rotavirus was significantly higher than that of dams immunized with rotavirus only. the antirotavirus iga level in feces of dams immunized orally with rotavirus was ... | 1995 | 7622883 |
| viability and enzymatic activity of bifidobacteria in milk. | bifidobacterium breve ncfb 2258, bifidobacterium bifidum ncfb 2715, bifidobacterium longum atcc 15707, bifidobacterium angulatum atcc 27535, and lactobacillus acidophilus n2 were evaluated for viability and beta-galactosidase and alpha-galactosidase activities under conditions of refrigerated and frozen storage in reconstituted ndm. beta- and alpha-galactosidase activities were variable. bifidobacterium angulatum 27535 exhibited much greater enzymatic activities than those of the other strains. ... | 1995 | 7745146 |
| absence of cholic acid 7 alpha-dehydroxylase activity in the strains of lactobacillus and bifidobacterium. | to investigate the presence of 7 alpha-dehydroxylase activity on bile acids in the bacterial strains of fermented milk products, 46 strains of lactobacillus casei, lactobacillus paracasei, lactobacillus rhamnosus, lactobacillus acidophilus, lactobacillus gasseri, bifidobacterium adolescentis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum, lactococcus lactis spp. lactis, and streptococcus salivarius spp. thermophilus were tested for their ability ... | 1994 | 7814703 |
| [effect of biapenem (l-627) on fecal flora in gnotobiotic mice and children]. | biapenem (l-627), a novel injectable carbapenem antibiotic, was studied with regard to its effect on mice inoculated with four types of bacteria and on the intestinal flora of pediatric patients. l-627 was given i.m., 40 mg/kg once daily for 5 consecutive days, to mice inoculated enterically with four types of bacteria (escherichia coli, enterococcus faecalis, bacteroides fragilis, and bifidobacterium breve). except for a mild decrease in e. coli, there were no major fluctuations in viable bacte ... | 1994 | 7877249 |
| analysis of the genome of the five bifidobacterium breve strains: plasmid content, pulsed-field gel electrophoresis genome size estimation and rrn loci number. | the genomes of the five bifidobacterium breve strains available from culture collections were compared by restriction endonuclease analysis. electrophoretic migration of undigested dna allowed us to detect a 5.6-kb circular plasmid in two of these strains. a restriction map of this plasmid was constructed using 10 enzymes. with drai endonuclease, pulsed-field gel electrophoresis has allowed the determination of the five b. breve genome sizes to 2.1 mb. this estimation was further confirmed for c ... | 1993 | 8100545 |
| [influence of s-1108 on intestinal bacterial flora]. | the effect of s-1108, a new oral cephem antibiotic, on intestinal bacterial flora was studied in tetra-contaminated mice and pediatric patients. s-1108 in a fine granular form was administered at a dose of 15 mg/kg once a day for 5 consecutive days to mice infected with escherichia coli, enterococcus faecalis, bacteroides fragilis and bifidobacterium breve. the viable fecal bacterial cell count of each of these 4 species of bacteria was slightly reduced in 5 days after the start of the drug admi ... | 1993 | 8107268 |
| adhesion of human bifidobacterial strains to cultured human intestinal epithelial cells and inhibition of enteropathogen-cell interactions. | thirteen human bifidobacterial strains were tested for their abilities to adhere to human enterocyte-like caco-2 cells in culture. the adhering strains were also tested for binding to the mucus produced by the human mucus-secreting ht29-mtx cell line in culture. a high level of calcium-independent adherence was observed for bifidobacterium breve 4, for bifidobacterium infantis 1, and for three fresh human isolates from adults. as observed by scanning electron microscopy, adhesion occurs to the a ... | 1993 | 8285709 |
| phenotypic and genomic analyses of human strains belonging or related to bifidobacterium longum, bifidobacterium infantis, and bifidobacterium breve. | a numerical analysis based on phenotypic characteristics (89 enzymatic tests and 49 carbohydrate acidification tests), in which experimental strips from biomerieux-api, la balme les grottes, france, were used, was performed to characterize 82 new isolates belonging or related to bifidobacterium longum, bifidobacterium infantis, and bifidobacterium breve. a total of 72 strains were isolated from child or adult feces, and the other strains were obtained from human vaginas and bronchi. in this stud ... | 1993 | 8347514 |
| the effects of transgalactosylated oligosaccharides on gut flora metabolism in rats associated with a human faecal microflora. | the effect on various caecal bacteria and their metabolic activities of feeding diet containing transgalactosylated oligosaccharides (tos) with or without bifidobacterium breve (administered in the drinking water) was investigated in rats colonized with a human faecal microflora. tos (5% w/w in diet) or tos plus b. breve, given for 4 weeks, induced increases in caecal concentration of total anaerobic bacteria, lactobacilli and bifidobacteria, and decreases in numbers of enterobacteria. caecal ph ... | 1993 | 8349528 |
| analysis of intestinal flora of a patient with congenital absence of the portal vein. | a 14-year-old female patient, admitted for a closer examination of liver tumour (hepatocellular adenoma), was diagnosed as having a congenital absence of the portal vein. the blood ammonia level (approximately 120 micrograms dl-1) in the superior mesenteric vein was markedly low compared to the normal value of 300-350 micrograms dl-1 in the portal vein. the decreased ammonia concentration and urease activity of the patient's faeces were demonstrated. the dominant intestinal flora in the faeces o ... | 1993 | 8364525 |
| neonatal meningitis caused by bifidobacterium breve. | we are reporting a male neonate with meningitis caused by bifidobacterium breve. this is only the second case reported so far to our knowledge. the patient's clinical course was excellent and inflammatory indications, such as serum c-reactive protein, were weak. although the antibiotics used for the patient were effective against this bacterium both in vitro and in vivo, two relapses occurred which might have been caused by an incomplete remission due to the low permeability of antibiotics throu ... | 1996 | 8733913 |
| identification of bifidobacteria from dairy products and evaluation of a microplate hybridization method. | sixteen strains of bifidobacterium isolated from 15 dairy products such as yogurt, cultured milk, butter and cheese were characterized on the basis of phenotypic characteristics and dna similarities were examined by a microplate hybridization method. three of the strains were identified as bifidodobacterium longum, one strain was identified as bifidobacterium bifidm, and one strain was assigned to the species bifidobacterium breve on the basis of phenotypic characteristics, and this identificati ... | 1996 | 8854183 |
| growth characteristics of bifidobacteria in infant formulas. | four species of bifidobacteria, bifidobacterium bifidum (atcc 15696), bifidobacterium breve (atcc 15700), bifidobacterium infantis (atcc 15697), and bifidobacterium longum (atcc 15708), were grown anaerobically at 37 degrees c in lactobacilli mrs broth with 0.5% cysteine-hc1 and inoculated at 2.5% into three types of infant formula (based on soy, or milk, or casein hydrolysate) and in nonfat milk followed by incubation at 37 degrees c for 24 h. in most cases, the logarithmic phase of growth for ... | 1996 | 8872711 |
| effect of bifidogenic factors on growth characteristics of bifidobacteria in infant formulas. | a bifidogenic factor, lactulose or fructooligosaccharides, was added (0.5%) into infant formula based on soy or infant formula with hydrolyzed casein. the infant formulas were then inoculated (2.5%) with bifidobacterium bifidum (atcc 15696), bifidobacterium breve (atcc 15700), bifidobacterium infantis (atcc 15697), or bifidobacterium longum (atcc 15708) or their mixture (mixed culture) and incubated at 37 degrees c for 24 h. lactulose did not influence maximal counts or generation times in eithe ... | 1996 | 8872712 |
| role of intestinal bacteria in ileal ulcer formation in rats treated with a nonsteroidal antiinflammatory drug. | the role of intestinal bacteria in induction and repression of ulcer formation in the ileum of rats treated with one of the nonsteroidal antiinflammatory drugs (nsaids), 5-bromo-2-(4-fluorophenyl)-3-(4-methylsulfonylphenyl) thiophene (bfmet), was examined in this study. bfmet was administered by intragastric gavage once at doses of 500-1,500 mg/kg of body weight to wistar rats treated with and without antibiotics (bacitracin, neomycin, streptomycin), germ-free rats and gnotobiotic rats, and 72 h ... | 1996 | 8887349 |
| lactobacillus- and bifidobacterium-mediated antigenotoxicity in the colon of rats. | lactic acid bacteria (lab) are proposed to have several beneficial effects, including the inactivation of carcinogens. we have studied the potential of lactobacillus acidophilus (from a commercially available yogurt), lactobacillus gasseri (p79), lactobacillus confusus (dsm20196), streptococcus thermophilus (ncim 50083), bifidobacterium breve and bifidobacterium longum (from human infant stool) to prevent the induction of dna damage by n-methyl-n'-nitro-n-nitrosoguanidine (mnng, 7.5 mg/kg body w ... | 1996 | 8910918 |
| cloning and nucleotide sequence of the beta-d-glucosidase gene from bifidobacterium breve clb, and expression of beta-d-glucosidase activity in escherichia coli. | genomic dna encoding a beta-d-glucosidase (ec 3.2.1.21), which has beta-d-fucosidase activity, was cloned from bifidobacterium breve clb. we sequenced a 1.9-kbp cloned dna fragment that contained a single open reading frame encoding 460 amino acids with a calculated molecular mass of 51,513 da. a putative ribosome binding site was found 5 bp upstream of the initiation codon. the amino acid sequence of this beta-d-glucosidase from bifidobacterium breve clb had 46% identity with that of beta-gluco ... | 1996 | 8988633 |
| involvement of trihydroxyconjugated bile salts in cholesterol assimilation by bifidobacteria. | to determine the conditions of cholesterol assimilation,various strains of bifidobacterium species were cultured in the presence of cholesterol and bile salts. during culturing, bifidobacterium breve atcc 15700 assimilates cholesterol in the presence of oxgall at ph values lower than 6. this strain was selected to study the influence of conjugated (taurocholic acid) and deconjugated (cholic acid) bile salts on cholesterol assimilation. b. breve atcc 15700 assimilated cholesterol(up to 51%) when ... | 1997 | 9003583 |
| purification and characterization of beta-d-glucosidase (beta-d-fucosidase) from bifidobacterium breve clb acclimated to cellobiose. | the beta-d-glucosidase (ec. 3.2.1.21) activity of bifidobacterium breve 203 was increased by acclimation with cellobiose, and the enzyme was purified to homogeneity from cell-free extracts of an acclimatized strain of b. breve clb, by ammonium sulfate fractionation and column chromatographies of anion-exchange, gel filtration, gigapaite, and hydrophobic interaction. this enzyme had not only beta-d-glucosidase activity but also beta-d-fucosidase activity, which is specific to bifidobacteria in in ... | 1996 | 9063964 |
| specific species of intestinal bacteria influence the induction of aberrant crypt foci by 1,2-dimethylhydrazine in rats. | to shed light on the association of intestinal microflora with the development of colon cancer, we studied the modifying effects of intestinal microflora on the occurrence of 1,2-dimethylhydrazine (dmh)-induced colonic aberrant crypt foci (acf) in germfree (gf), gnotobiotic (gb) and conventionalized (cvd) rats. in the first part of this study, 10 week old germfree fischer-344 rats were randomly assigned to three groups and two groups of rats were orally inoculated with mixtures of pure culture o ... | 1997 | 9065820 |
| early administration of bifidobacterium breve to preterm infants: randomised controlled trial. | to investigate the colonisation with bifidobacterium breve of the bowels of very low birthweight (vlbw) infants. | 1997 | 9135288 |
| digoxigenin-labeled deoxyribonucleic acid probes for the enumeration of bifidobacteria in fecal samples. | the numbers of bifidobacteria in fecal samples were specifically determined by colony hybridization with the mixture of digoxigenin-labeled dna probes that were prepared from whole chromosomal dna of bifidobacterium longum 6001 and bifidobacterium adolescentis 6003. these dna probes strongly hybridized with dna of b. longum, b. adolescentis, bifidobacterium breve, bifidobacterium suis, bifidobacterium infantis, bifidobacterium bifidum, bifidobacterium angulatum, and bifidobacterium animalis. det ... | 1997 | 9241587 |
| growth, viability, and proteolytic activity of bifidobacteria in whole camel milk. | four species of bifidobacteria were evaluated for growth, viability, and proteolytic activity in whole camel milk, and comparison was made with whole cow milk. growth of all species in either whole milk was characterized by the appearance of two logarithmic phases following anaerobic incubation at 37 degrees c for 36 h. the growth rate of bifidobacterium longum 15,707 was higher in camel milk than in bovine milk and was higher for bifidobacterium angulatum 27,535 in bovine milk than in camel mil ... | 1998 | 9532489 |
| characterization of bifidobacterium strains for use in soymilk fermentation. | soybean milk, which serves as a base for a variety of beverages, contains raffinose, stachyose, pentanal and n-hexanal; the former two may be responsible for flatulence after fermentation, whilst the latter two for a beany flavour. twenty-seven strains of bifidobacterium were analyzed for their alpha-galactosidase activity and the production of lactic and acetic acids to determine their potential for use in the production of fermented soymilk. the behaviour of three strains in soymilk was studie ... | 1998 | 9553799 |
| cell-free whey from milk fermented with bifidobacterium breve c50 used to modify the colonic microflora of healthy subjects. | the ingestion of viable bacteria is thought to be required to modify intestinal microflora. in the present study, the effects on fecal flora of consumption of cell-free concentrated whey from milk that had been fermented with bifidobacterium breve c50 was tested using 10 healthy human volunteers. results were compared with effects of a commercial milk formula that had been fermented with streptococcus thermophilus and b. breve c50 and given to 10 control subjects. nitroreductase and beta-glucuro ... | 1998 | 9621224 |
| inhibitory effects of bifidobacterium spp. isolated from a healthy korean on harmful enzymes of human intestinal microflora. | five hundreds of bifidobacteria were isolated from a healthy korean and the inhibitory effects of these isolated bacteria on harmful enzymes of human intestinal microflora were examined by cocultivation of the isolated bifidobacteria with e. coli or total human intestinal microflora. in comparison with the results of e. coli or intestinal microflora cultivation, bifidobacterium breve k-110, b. breve k-111 and b. infantis k-525 effectively inhibited harmful enzymes (beta-glucuronidase and tryptop ... | 1998 | 9875515 |
| increased growth of bifidobacterium and eubacterium by germinated barley foodstuff, accompanied by enhanced butyrate production in healthy volunteers. | germinated barley foodstuff (gbf) derived from the aleurone and scutellum fractions of germinated barley mainly consists of low-lignified hemicellulose and glutamine-rich protein. gbf improves the proliferation of intestinal epithelial cells and defecation, through the bacterial production of short chain fatty acids (scfa), especially butyrate. in this study we investigated the mechanism of production of butyrate by microflora in humans and in vitro. daily administration of 9 g gbf for 14 succes ... | 1999 | 9917526 |
| intestinal barrier function and cow's milk sensitization in guinea pigs fed milk or fermented milk. | the respective effect of milk and fermented milks on intestinal barrier capacity and on sensitization to beta-lactoglobulin was studied using a guinea pig model of cow's milk allergy. | 1999 | 9932854 |
| protection against influenza virus infection of mice fed bifidobacterium breve yit4064. | mice fed bifidobacterium breve yit4064 and immunized orally with influenza virus were more strongly protected against influenza virus infection of the lower respiratory tract than ones immunized with influenza virus only. the number of mice with enhanced anti-influenza virus immunoglobulin g (igg) in serum upon oral administration of b. breve yit4064 and oral immunization with influenza virus was significantly greater than that upon oral immunization with influenza virus only. these findings dem ... | 1999 | 10066652 |
| molecular characterisation of a 5.75-kb cryptic plasmid from bifidobacterium breve ncfb 2258 and determination of mode of replication. | a small cryptic plasmid originating from bifidobacterium breve ncfb 2258 was cloned and its complete nucleotide sequence determined. pcibb1 is a circular dna molecule, 5750 bp in size with a gc composition of 57%. computer-assisted analysis identified 10 possible open reading frames (orfs), seven of which could be assigned no function from homology searches. one orf, rep (380 amino acids), was postulated to encode a replication protein similar to known replication proteins of rolling circle repl ... | 1999 | 10339821 |
| [trial of oral administration of bifidobacterium breve for the prevention of rotavirus infections]. | it was investigated that bifidobacterium breve yit4064 (b. breve yit4064), which had augmented iga production and prevented rotavirus-induced diarrhea in mice, prevented rotavirus infection in infants. the effect of b. breve yit4064 was evaluated in ten infants from an infants home who received 50 mg of the bacterium every day for 28 days (the b. breve group). nine infants did not receive this (the control group). though rotavirus shedding in the control group was detected from 2 (a total of 5 s ... | 1999 | 10356887 |
| immunomodulatory function of lactic acid bacteria. | using mice, we found that oral administration of bifidobacterium breve yit4064 (b. breve) activated the humoral immune system, augmented anti-rotavirus iga production or anti-influenza virus (ifv) igg production and protected against rotavirus infection or influenza infection, respectively. furthermore, when the b. breve was given to infants from an infant home, there was a significant reduction of the frequency of rotavirus shedding in stool samples during the administration of the bacteria. it ... | 1999 | 10532394 |
| effects of fructooligosaccharides and their monomeric components on bile salt resistance in three species of bifidobacteria. | the influence of fructooligosaccharides (fos) and their monomeric components on bile salt resistance of bifidobacterium breve atcc 15700, bif. longum atcc 15707 and bif. animalis atcc 25527 was examined. the neosugars induced fructofuranosidase activities for the degradation of these saccharides. for the three strains tested the growth was identical and bile salts had the same inhibitory effect on growth whatever the carbohydrate used. the survival of bif. breve and bif. longum, in the presence ... | 2000 | 10849172 |
| cordycepin: selective growth inhibitor derived from liquid culture of cordyceps militaris against clostridium spp. | the growth responses of nine human intestinal bacteria to liquid culture of cordyceps militaris link. pt. (ascomycotina: clavicipitaceae) collected from a pupa of bombyx mori l. (lepidoptera: bombycidae) were examined using spectrophotometric and impregnated paper disk methods and compared to those of tetracycline and chloramphenicol, as well as those of coptis japonica root-derived berberine chloride. the biologically active constituent of the cultures was characterized as cordycepin (3'-deoxya ... | 2000 | 10898616 |
| enhanced antigen-specific delayed-type hypersensitivity and immunoglobulin g2b responses after oral administration of viable lactobacillus casei yit9029 in wistar and brown norway rats. | in this study, the effects of orally administered viable lactobacillus casei shirota strain yit9029 on the immunity parameters of wistar and brown norway rats were examined. for this purpose, we used the trichinella spiralis host resistance model. two weeks before and during t. spiralis infection, rats were fed 10(9) viable l. casei bacteria 5 days per week. the t. spiralis-specific delayed-type hypersensitivity (dth) response was significantly enhanced in both wistar and brown norway rats given ... | 2001 | 11427423 |
| the effect of nisin on the physiology of bifidobacterium thermophilum. | the effects of nisin on lactate accumulation, growth, and fe(iii) binding by bifidobacterium thermophilum (atcc 25866) and bifidobacterium breve (atcc 15700) were investigated. nisin inhibited lactate production by b. thermophilum at concentrations of less than 1 microg/ml, but this effect could be largely eliminated by pretreatment of the organism with 100 to 400 microm al(iii) or la(iii). nisin also inhibited the growth of b. thermophilum at concentrations of 2 to 3 microg/ml, with lower conce ... | 2001 | 11510661 |
| combination therapy with bifidobacterium breve, lactobacillus casei, and galactooligosaccharides dramatically improved the intestinal function in a girl with short bowel syndrome: a novel synbiotics therapy for intestinal failure. | | 2001 | 11575457 |
| preventive effects of bifidobacterium- and lactobacillus-fermented milk on the development of inflammatory bowel disease in senescence-accelerated mouse p1/yit strain mice. | we recently discovered inflammatory bowel disease (ibd) in the ileum and cecum of samp1/yit strain mice under specific pathogen-free (spf) conditions. to determine the effect of lactic acid bacteria (lab - bifidobacterium breve, bifidobacterium bifidum and lactobacillus acidophilus)-fermented milk on the prevention of ibd in samp1/yit strain mice, we compared the disease severity on the intestinal inflammation among the group of mice fed saline, unfermented milk or lab-fermented milk. | 2001 | 11684822 |
| effects of probiotic administration upon the composition and enzymatic activity of human fecal microbiota in patients with irritable bowel syndrome or functional diarrhea. | in a clinical trial, 10 patients suffering from irritable bowel syndrome or functional diarrhea were administered the probiotic preparation vsl-3. preliminary results indicated that administration of vsl-3 improved the clinical picture and changed the composition and biochemistry of fecal microbiota. titer variations of intestinal bacterial groups were evaluated by culture and pcr techniques. a significant increase in lactobacilli, bifidobacteria and streptococcus thermophilus was observed as a ... | 2001 | 11686387 |
| production and application of new monoclonal antibodies specific for a fecal helicobacter pylori antigen. | the aim of the present study was to establish monoclonal antibodies that could be used to produce a diagnostic test composed of one kind of monoclonal antibody recognizing a fecal helicobacter pylori antigen. the need to develop such a test arose from disadvantages of the diagnostic test that uses a polyclonal antibody or plural kinds of monoclonal antibodies, such as the lower specificity for h. pylori antigen and the difficulty of reproduction with consistent quality. mice were immunized with ... | 2002 | 11777832 |
| partial characterization of bifidobacterium breve c50 cell-free whey compounds inducing modifications to the intestinal microflora. | cell-free whey obtained from milk fermented with bifidobacterium breve c50 (bb c50) has been shown to modify the intestinal flora in humans and mice. previous work showed that no antibiotic-like or barrier effect due to overgrowing bifidobacteria was implied in the microbial modifications. the present study was focused on characterizing the compounds and mechanisms involved. protein, sugar, and enzymatic profiles of bb c50 whey were therefore determined and compared to those of a whey unable to ... | 2002 | 12146468 |
| evaluation of bifidobacterium breve strain yakult-fermented soymilk as a probiotic food. | we evaluated the effects of bifidobacterium breve-fermented soymilk on probiotic function. an administered strain of b. breve strain yakult was capable of growing in soymilk with no additives as high as 10(9) cfu/ml. during storage of the fermented soymilk at 10 degrees c for 20 days, viable counts of the strain did not change. the growth inhibition of the strain in a bile-containing medium was lessened by the addition of soy protein. in human feeding experiments, the administered b. breve was r ... | 2003 | 12457587 |
| a novel synbiotic therapy dramatically improved the intestinal function of a pediatric patient with laryngotracheo-esophageal cleft (ltec) in the intensive care unit. | to demonstrate the beneficial effects of synbiotic therapy (combined use of probiotics and prebiotics) in critically ill patients, we designed a new protocol for such therapy. three agents were used as synbiotics: bifidobacterium breve, lactobacillus casei, and galactooligosaccharides. more than 1 x 10(9) of probiotic bacteria were contained in each 1.0 g pack. we administered 3.0 g per day of each agent to the patient.a critically ill 9-month-old girl with laryngotracho-esophageal cleft (type i ... | 2002 | 12468374 |
| pcr detection of bifidobacterium strains and streptococcus thermophilus in feces of human subjects after oral bacteriotherapy and yogurt consumption. | streptococcus thermophilus, bifidobacterium infantis y1 and bifidobacterium breve y8 strains were identified and enumerated by pcr assay in human fecal samples after intake of the pharmaceutical preparation vsl-3 or yogurt. thi/thii primer set, specific for s. thermophilus, was selected testing its specificity against several strains of enterococci, streptococci and other genera colonizing the human intestine. a culture-independent pcr protocol, developed in this study, allowed to directly detec ... | 2003 | 12485746 |
| conjugated linoleic acid biosynthesis by human-derived bifidobacterium species. | to assess strains of lactobacillus, lactococcus, pediococcus and bifidobacterium for their ability to produce the health-promoting fatty acid conjugated linoleic acid (cla) from free linoleic acid. | 2003 | 12492934 |
| glucose but not polypeptone reduces the effect of probiotic preparations to stimulate carbohydrate breakdown and reduce net ammonia production by pig cecal bacteria in vitro. | probiotic preparations are used to prevent or treat diarrhea. probiotic preparations increase the in vitro breakdown of carbohydrates and decrease that of protein by mixed cecal bacteria in the absence of readily fermentable materials. diarrhea can increase the influx of readily digestible materials into the large intestine. therefore, we compared production of organic acids and ammonia in batch cultures using pig cecal contents with or without probiotic preparations (clostridium butyricum, lact ... | 2001 | 12639405 |
| cholic acid accumulation and its diminution by short-chain fatty acids in bifidobacteria. | cholic acid (ca) transport was investigated in nine intestinal bifidobacterium strains. upon energization with glucose, all of the bifidobacteria accumulated ca. the driving force behind ca accumulation was found to be the transmembrane proton gradient (delta ph, alkaline interior). the levels of accumulated ca generally coincided with the theoretical values, which were calculated by the henderson-hasselbalch equation using the measured internal ph values of the bifidobacteria, and a pk(a) value ... | 2003 | 12904543 |
| purification and characterization of ginsenoside ra-hydrolyzing beta-d-xylosidase from bifidobacterium breve k-110, a human intestinal anaerobic bacterium. | beta-d-xylosidase (ec 3.2.1.37) has been purified from ginsenoside ra-metabolizing bifidobacterium breve k-110, which was isolated from human intestinal microflora. beta-d-xylosidase was purified to apparent homogeneity by a combination of ammonium sulfate precipitation, qae-cellulose, butyl-toyopearl, hydroxyapatit and q-sepharose column chromatographies with the final specific activity of 51.8 micromol/min/mg. molecular weight of beta-d-xylosidase is 49 kda by sds-page and gel filtration, whic ... | 2003 | 12913270 |
| investigation of protein export in bifidobacterium breve ucc2003. | the molecular interactions between the bifidobacterial cell and its natural environment, namely, the gastrointestinal tract of its host, are particularly important in understanding the presumed positive effects of bifidobacterium on the health status of the host. in this study an export-specific reporter system, designed for use in gram-positive organisms and based on the use of the staphylococcal nuclease (nuc) as a reporter, was employed to identify exported proteins in bifidobacterium breve u ... | 2003 | 14660341 |
| purification and characterization of alpha-l-arabinopyranosidase and alpha-l-arabinofuranosidase from bifidobacterium breve k-110, a human intestinal anaerobic bacterium metabolizing ginsenoside rb2 and rc. | two arabinosidases, alpha-l-arabinopyranosidase (no ec number) and alpha-l-arabinofuranosidase (ec 3.2.1.55), were purified from ginsenoside-metabolizing bifidobacterium breve k-110, which was isolated from human intestinal microflora. alpha-l-arabinopyranosidase was purified to apparent homogeneity, using a combination of ammonium sulfate fractionation, deae-cellulose, butyl toyopearl, hydroxyapatite ultrogel, qae-cellulose, and sephacryl s-300 hr column chromatography, with a final specific ac ... | 2003 | 14660356 |
| lactic acid bacteria secrete metabolites retaining anti-inflammatory properties after intestinal transport. | probiotic bacteria have a beneficial effect on intestinal inflammation. in this study, we have examined the effect of lactic acid and commensal gram positive (+) bacteria conditioned media (cm) on tumour necrosis factor alpha (tnf-alpha) release and the mechanisms involved. | 2004 | 15138208 |
| probiotics in the treatment of irritable bowel syndrome. | irritable bowel syndrome (ibs) may be diagnosed on the presence of symptoms, according to rome ii criteria, [corrected] and some studies have shown that abnormal colonic fermentation may be an important factor in the development of symptoms in some patients with ibs. since the fermentation [corrected] of substrates by the intestinal flora may play a key role in the use of probiotics in the treatment of ibs, seventy [corrected] patients (31 [corrected] males, 39 [corrected] females), mean age 40 ... | 2004 | 15220671 |
| growth-promoting effects of lactoferrin on l. acidophilus and bifidobacterium spp. | we investigated the effects of lactoferrin on the growth of l. acidophilus ch-2, bifidobacterium breve atcc 15700, b. longum atcc 15707, b. infantis atcc 15697, and b. bifidum atcc 15696. the growth of l. acidophilus was stimulated by bovine holo-lactoferrin but not by apo-lactoferrin. with bifidobacteria, bovine lactoferrin stimulated growth of three strains: b. breve, b. infantis and b. bifidum under certain conditions. both apoprotein and holoprotein had similar effects. however, b. longum gr ... | 2004 | 15222478 |
| effects of long-term consumption of a fermented infant formula (with bifidobacterium breve c50 and streptococcus thermophilus 065) on acute diarrhea in healthy infants. | to determine whether long-term consumption of a fermented infant formula could influence the incidence of acute diarrhea and its severity in healthy infants. | 2004 | 15269618 |
| mining the microbiota of the neonatal gastrointestinal tract for conjugated linoleic acid-producing bifidobacteria. | this study was designed to isolate different strains of the genus bifidobacterium from the fecal material of neonates and to assess their ability to produce the cis-9, trans-11 conjugated linoleic acid (cla) isomer from free linoleic acid. fecal material was collected from 24 neonates aged between 3 days and 2 months in a neonatal unit (erinville hospital, cork, ireland). a total of 46 isolates from six neonates were confirmed to be bifidobacterium species based on a combination of the fructose- ... | 2004 | 15294796 |
| characterization of the groel and groes loci in bifidobacterium breve ucc 2003: genetic, transcriptional, and phylogenetic analyses. | the bacterial heat shock response is characterized by the elevated expression of a number of chaperone complexes, including the groel and groes proteins. the groes and groel genes are highly conserved among eubacteria and are typically arranged as an operon. genome analysis of bifidobacterium breve ucc 2003 revealed that the groes and groel genes are located in different chromosomal regions. the heat inducibility of the groel and groes genes of b. breve ucc 2003 was verified by slot blot analysi ... | 2004 | 15466567 |
| effects of bifidobacterium breve supplementation on intestinal flora of low birth weight infants. | it is known that the bifidobacteria flora play important roles in mucosal host defense and can prevent infectious diseases. because bacterial populations develop during the first day of life, the authors examined whether the early administration of bifidobacteria has a positive effect on the health of low birth weight infants. | 2004 | 15491374 |
| experience of long-term synbiotic therapy in seven short bowel patients with refractory enterocolitis. | probiotic and prebiotic therapies are potent new strategies to treat various intestinal diseases, including inflammatory bowel disease and viral and bacterial infections. synbiotics is defined as the combined use of probiotics and prebiotics and is expected to have a stronger effect on intestinal diseases than probiotics or prebiotics alone, but there has been no report of its clinical application. the authors designed a protocol for synbiotic therapy composed of bifidobacterium breve, lactobaci ... | 2004 | 15547835 |
| [intestinal bacterial colonisation and translocation in c3h/hej conventional mice fed a unique dose of live or dead bifidobacterium breve c50]. | the efficiency and safety of use of bifidobacterium breve c50 (bbc50), a potential probiotic, was assessed as regards intestinal microbial colonisation and bacterial translocation. a suspension of bbc50, containing 1-5 to 107-108 live bacteria, was fed to c3h/hej mice. the passage of live bbc50 was not demonstrated by culture either in the intestine or extra-intestinal organs. however, mice receiving the highest dose of live bacteria harbored more lactobacilli and less bacteroides fragilis group ... | 2004 | 15550897 |
| antimicrobial susceptibility of bifidobacteria. | the aim of our study was to analyse the antibiotic susceptibility of various strains of bifidobacterium spp. to a wide range of antimicrobial agents. | 2004 | 15574479 |
| gene structure and transcriptional organization of the dnak operon of bifidobacterium breve ucc 2003 and application of the operon in bifidobacterial tracing. | the incorporation and delivery of bifidobacterial strains as probiotic components in many food preparations expose these microorganisms to a multitude of environmental insults, including heat and osmotic stresses. we characterized the dnak gene region of bifidobacterium breve ucc 2003. sequence analysis of the dnak locus revealed four genes with the organization dnak-grpe-dnaj-orf1, whose deduced protein products display significant similarity to corresponding chaperones found in other bacteria. ... | 2005 | 15640225 |
| [detection of oxalobacter formigenes in human feces and study of related genes in a new oxalate-degrading bacterium]. | the first objective of the present study was to examine the presence of oxalobacter formigenes (an oxalate-degrading bacterium in the human intestine) according to sex in a large number of japanese. the second objective was to study the presence of three related genes in bifidobacterium breve, which is considered to be a new oxalate-degrading bacterim. fecal samples were collected from 55 male and 37 female healthy volunteers. o. formigenes was detected by a polymerase chain reaction (pcr) and a ... | 2003 | 12968475 |
| the effect of lactobacillus acidophilus and bifidobacterium spp. administration on the morphology of the gastrointestinal tract, liver and pancreas in piglets. | the aim of the study was to investigate the influence of administration of probiotic bacteria on morphology of the gastrointestinal tract, liver and pancreas. the experiment was performed on 15 piglets at the age from 3 to 35 days, intragastrically administered with bifidobacterium breve, b. animalis, and lactobacillus acidophilus bacteria. in all piglets examined, the development of the gastrointestinal tract, liver and pancreas was observed to progress normally. after microflora administration ... | 2005 | 15794471 |
| quantitative real-time pcr assays to identify and quantify fecal bifidobacterium species in infants receiving a prebiotic infant formula. | a healthy intestinal microbiota is considered to be important for priming of the infants' mucosal and systemic immunity. breast-fed infants typically have an intestinal microbiota dominated by different bifidobacterium species. it has been described that allergic infants have different levels of specific bifidobacterium species than healthy infants. for the accurate quantification of bifidobacterium adolescentis, bifidobacterium angulatum, bifidobacterium bifidum, bifidobacterium breve, bifidoba ... | 2005 | 15870317 |
| probiotic supplementation improves tolerance to helicobacter pylori eradication therapy--a placebo-controlled, double-blind randomized pilot study. | h. pylori is the major cause of chronic gastritis, and a risk factor for peptic ulcer and gastric cancer. | 2005 | 15882248 |
| [high expression of alpha-d-galactosidase gene (aga1) of bifidobacterium breve 203 in escherichia coli]. | alpha-d-galactosidase gene (agal) of bifidobacterium breve 203 was cloned into temperature expression vector pbv220 and transformed into e. coli. the recombinant plasmid pbvagal was induced to express with temperature. the specific activities of recombinant enzyme agal in e. coli dh5alpha, e. coli dh10b and e. coli bl21 were 28.08 u/mg, 19.44 u/mg and 13.85 u/mg, respectively. the recombinant plasmid pbvagal is more stable in e. coli bl21. the molecular weight of agal as determined by sds-page w ... | 2005 | 15989269 |
| production of oligosaccharides in yogurt containing bifidobacteria and yogurt cultures. | yogurts were prepared by using yogurt cultures combined to mixed cultures of bifidobacteria (bifidobacterium animalis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, and bifidobacterium longum) and by adding a preincubation step (1.5 h at 50 degrees c) with bifidobacteria to the conventional method of manufacture in order to produce oligosaccharides. the survival of bifidobacteria was drastically affected during storage of yogurts, except for products containing b. ani ... | 2002 | 12086039 |
| 2-amino-3-carboxy-1,4-naphthoquinone affects the end-product profile of bifidobacteria through the mediated oxidation of nad(p)h. | glucose metabolism of bifidobacteria in the presence of 2-amino-3-carboxy-1,4-naphthoquinone (acnq), a specific growth stimulator for bifidobacteria, and ferricyanide (fe(cn)(6)(3-)) as an extracellular electron acceptor was examined using resting cells of bifidobacterium longum and bifidobacterium breve. nad(p)h in the cells is oxidized by acnq with the aid of diaphorase activity, and reduced acnq donates the electron to fe(cn)(6)(3-). exogenous oxidation of nadh by the acnq/fe(cn)(6)(3-) syste ... | 2002 | 12073135 |
| a probiotic mixture alleviates symptoms in irritable bowel syndrome patients: a controlled 6-month intervention. | irritable bowel syndrome is a gastrointestinal disorder of unknown aetiology. the effect of probiotics in this syndrome remains unclear. | 2005 | 16128676 |
| the clpb gene of bifidobacterium breve ucc 2003: transcriptional analysis and first insights into stress induction. | the so-called clp genes, which encode components of the clp proteolytic complex, are widespread among bacteria. the bifidobacterium breve ucc 2003 genome contains a clpb gene with significant homology to predicted clpb genes from other members of the actinobacteridae group. the heat- and osmotic-inducibility of the b. breve ucc 2003 clpb homologue was verified by slot-blot analysis, while northern blot and primer extension analyses showed that the clpb gene is transcribed as a monocistronic unit ... | 2005 | 16151199 |
| macrolide resistance mediated by a bifidobacterium breve membrane protein. | a gene coding for a hypothetical membrane protein from bifidobacterium breve was expressed in lactococcus lactis. immunoblotting demonstrated that this protein is located in the membrane. phenotypical changes in sensitivity towards 21 antibiotics were determined. the membrane protein-expressing cells showed higher levels of resistance to several macrolides. | 2005 | 16189127 |
| genetic and transcriptional organization of the clpc locus in bifidobacterium breve ucc 2003. | a homolog of the clpc atpase gene was identified in the genome of bifidobacterium breve ucc 2003. since this gene is very well conserved among eubacteria, we employed a pcr-based approach using primers based on highly conserved regions of clpc proteins in order to identify homologous genes in other bifidobacterial species. analysis by slot blot, northern blot, and primer extension experiments showed that transcription of clpc is induced in response to moderate heat shock regimes. moreover, we id ... | 2005 | 16204550 |
| effects of specific lactic acid bacteria on the intestinal permeability to macromolecules and the inflammatory condition. | non-live probiotic bacteria and their fermentation products can be used in milk-based formula intended for healthy infants. the effects of a milk formula fermented with bifidobacterium breve and streptococcus thermophilus and heated/dehydrated to inactivate the micro-organisms have been reported over the last few years to decrease the intestinal permeability to macromolecules in experimental animals in vivo and more recently to down-regulate inflammatory condition in vitro. feeding guinea-pigs w ... | 2005 | 16214764 |
| bifidobacterium breve and streptococcus thermophilus secretion products enhance t helper 1 immune response and intestinal barrier in mice. | lactic acid bacteria or their secretion products can modulate immune responses differently in normal and inflammatory conditions. this comparative study analyzes the effect of oral administration of living lactic acid bacteria, or their conditioned media, on the epithelial and immune functions of colitis-prone c57bl/6 il-10-deficient mice. mice were untreated (control) or infected with helicobacter hepaticus with or without oral treatment with living bacteria, bifidobacterium breve c50 and strep ... | 2005 | 16246902 |
| the clgr protein regulates transcription of the clpp operon in bifidobacterium breve ucc 2003. | five clp genes (clpc, clpb, clpp1, clpp2, and clpx), representing chaperone- and protease-encoding genes, were previously identified in bifidobacterium breve ucc 2003. in the present study, we characterize the b. breve ucc 2003 clpp locus, which consists of two paralogous genes, designated clpp1 and clpp2, whose deduced protein products display significant similarity to characterized clpp peptidases. transcriptional analyses showed that the clpp1 and clpp2 genes are transcribed in response to mo ... | 2005 | 16321946 |
| prophage-like elements in bifidobacteria: insights from genomics, transcription, integration, distribution, and phylogenetic analysis. | so far, there is only fragmentary and unconfirmed information on bacteriophages infecting the genus bifidobacterium. in this report we analyzed three prophage-like elements that are present in the genomes of bifidobacterium breve ucc 2003, bifidobacterium longum ncc 2705, and bifidobacterium longum djo10a, designated bbr-1, bl-1, and blj-1, respectively. these prophagelike elements exhibit homology with genes of double-stranded dna bacteriophages spanning a broad phylogenetic range of host bacte ... | 2005 | 16332864 |
| genetic characterization of the bifidobacterium breve ucc 2003 hrca locus. | the bacterial heat shock response is characterized by the elevated expression of a number of chaperone complexes and transcriptional regulators, including the dnaj and the hrca proteins. genome analysis of bifidobacterium breve ucc 2003 revealed a second copy of a dnaj gene, named dnaj2, which is flanked by the hrca gene in a genetic constellation that appears to be unique to the actinobacteria. phylogenetic analysis using 53 bacterial dnaj sequences, including both dnaj1 and dnaj2 sequences, su ... | 2005 | 16332909 |
| molecular microbial analysis of bifidobacterium isolates from different environments by the species-specific amplified ribosomal dna restriction analysis (ardra). | one hundred and six isolates of the genus bifidobacterium, isolated from different environments (mainly gastrointestinal), were identified and classified taxonomically to species level by amplified ribosomal dna restriction analysis. two restriction endonucleases (sau3ai and bamhi) were chosen for aligning the 16s rrna sequences of 16 bifidobacterial species retrieved from various databases, to obtain species-specific restriction patterns. a rapid and accurate identification scheme was obtained ... | 2001 | 11451515 |
| determination of survival, identity and stress resistance of probiotic bifidobacteria in bio-yoghurts. | to determine the level of bifidobacteria in bio-yoghurts in the uk, identify the species, and compare the resistance of common bifidobacterium spp. to acidity and oxidative stress. | 2006 | 16478503 |
| antitumor activity of bifidobacterium spp. isolated from a healthy korean. | the antitumor activity of bifidobacterium breve k-110, and k-111, and b. infantis k-525 was investigated. these bifidobacterial cells and their cell wall preparations (wpg) significantly increased the survival rate of mice who had been intraperitoneally implanted with sarcoma 180 cells. solid tumor growth was inhibited even when the sarcoma 180 cells were implanted into the groins of the mice. however, the bifidobacterial cells did not show in vitro cytotoxicity against tumor cell lines. cell ki ... | 2000 | 11059828 |
| method for direct selection of potentially probiotic bifidobacterium strains from human feces based on their acid-adaptation ability. | a method for direct selection of acid-resistant bifidobacterium strains was developed by prolonged exposure of human feces to homologous lethal stress conditions. the recovered strains were intrinsically resistant to acidic gastric conditions (ph 2.0) and also showed good tolerance to high concentrations of bile salts and nacl. bifidobacterium breve and bifidobacterium adolescentis were, respectively, the infant- and adult-type bifidobacterial species showing the highest ability to develop an ac ... | 2006 | 16522337 |
| supernatant of bifidobacterium breve induces dendritic cell maturation, activation, and survival through a toll-like receptor 2 pathway. | commensal gut bacteria are essential for the development and maintenance of the gut's immune system. some bacteria strains, such as lactobacillus and bifidobacterium species, have been reported to provide protection from allergic and inflammatory bowel diseases. however, the interactions between these commensal bacteria and the immune system are largely unknown. | 2006 | 16522473 |
| antibiotic susceptibility of atopobium vaginae. | previous studies have indicated that a recently described anaerobic bacterium, atopobium vaginae is associated with bacterial vaginosis (bv). thus far the four isolates of this fastidious micro-organism were found to be highly resistant to metronidazole and susceptible for clindamycin, two antibiotics preferred for the treatment of bv. | 2006 | 16542416 |
| bioproduction of conjugated linoleic acid by probiotic bacteria occurs in vitro and in vivo in mice. | probiotics have been shown to reduce the incidence of colon cancer in animal models. the mechanisms responsible for this activity are poorly defined. conjugated linoleic acids (cla) are a group of isomers of linoleic acid (la) possessing anti-inflammatory and anticarcinogenic properties, which can be produced from la by certain bacterial strains. in this study, the ability of probiotic bacteria to exert anticarcinogenic effects through the production of cla was assessed. incubation of probiotic ... | 2006 | 16702308 |