| effect of dietary components on the indigenous oral bacterial flora of balb/c mice. | diet is recognized as one of the most important factors affecting the equilibrium of the oral bacterial flora. studies related to dental caries development have focused mainly on the effect of carbohydrates. in the present work, using swabbing coupled with an immuno-colony-blot assay, we followed the indigenous oral bacterial populations of balb/c mice fed diets with different concentrations of sucrose, starch, proteins, lipids, vitamins, and minerals for a period of 14 days. the results indicat ... | 1990 | 2324350 |
| superoxide dismutase activity in some strains of lactobacilli: induction by manganese. | dialyzed cell-free extract of lactobacilli was found to contain superoxide dismutase activity by using a test system in which superoxide ion is generated by xanthine oxidase. the specific activities of lactobacillus acidophilus atcc 4356, lactobacillus murinus atcc 35020, lactobacillus acidophilus crl 358, lactobacillus plantarum atcc 8014, lactobacillus casei crl 431, lactobacillus plantarum crl 353, lactobacillus fermentum atcc 9338, lactobacillus buchneri ncdo 110, and lactobacillus fermentum ... | 1989 | 2632048 |
| antibiotic resistance and production of inhibitory substances among bacterial strains isolated from the oral cavities of balb/c mice. | in the oral cavities of balb/c mice, microbial population levels are regulated by multifactorial processes. factors include the production of inhibitory substances and the exchange of genetic material. in this work, 371 isolates from different sites (saliva, tongue, teeth, and mucosa) of the oral cavities of balb/c mice were screened for resistance to antibiotics and antimicrobial activity. antibiotic-resistant strains represented 25% of the total flora. among the predominant species, all the s. ... | 1988 | 3143751 |
| aspartate aminotransferase of lactobacillus murinus. | aspartate aminotransferase from lactobacillus murinus is thermostable, its activity being not changed for two months at temperatures between 4 and -70 degrees c. maximum activity was observed at 40 degrees c and ph 7.3 in phosphate buffer (30 mmol/l). delta g* value of 26.3 kj/mol was calculated from the arrhenius plot. the km values for l-aspartate and 2-oxoglutarate at ph 7.3 were 25 and 100 mmol/l, respectively. sodium maleate and glutamate acted as inhibitors of the enzyme activity. the ki v ... | 1988 | 3203926 |
| bacteriology of the oral cavity of balb/c mice. | to be used as a model in dental research, an animal must fulfil experimental needs and information on the composition and variation of its oral flora must be available. only limited data are available on the indigenous oral bacterial flora of balb/c mice. in this work, a total of 671 isolates from different sites (saliva, tongue, teeth, and mucosa) of the oral cavity of balb/c mice were identified. only 18 different species were isolated, which indicates the relative simplicity of the flora. the ... | 1986 | 3768807 |
| ["lactobacillus murinus" n. sp., a new species of the autochtoneous dominant flora of the digestive tract of rat and mouse (author's transl)]. | lactobacillus murinus, a new species isolated from rat and mouse digestive tracts, is described. it belongs to the subgenus thermobacterium although it is able to ferment pentoses. the electrophoretic mobilities of soluble proteins and lactic dehydrogenase, the guanine + cytosine content (43.7%), the l-lysine-d-aspartic acid cell wall (b type, kandler), the immunological relationship with other lactobacillus species and also the aminoacid requirements show that it has to be assigned to a new spe ... | 1980 | 7425453 |
| changes in fecal microflora induced by intubation of mice with bacillus subtilis (natto) spores are dependent upon dietary components. | we examined changes in mouse fecal microflora after various dietary components and bacillus subtilis (natto) spores were delivered by intubation. the administration of intact spores of bacillus subtilis (natto) did not affect fecal enterobacteriaceae and enterococcus spp. in all three diet groups; on the other hand, it did affect fecal bacteroidaceae and lactobacillus spp., depending upon the diets fed. the administration of autoclaved spores did not alter fecal microflora. in vitro cultures of ... | 1999 | 10349722 |
| relative ability of orally administered lactobacillus murinus to predominate and persist in the porcine gastrointestinal tract. | five porcine-derived lactobacillus or pediococcus isolates administered to pigs (n = 4), either singly or as a combination at approximately 10(10) cfu per day varied with respect to intestinal survival and persistence. two lactobacillus murinus strains survived best and were excreted at approximately 10(7) to 10(8) cfu/g of feces. in contrast, pediococcus pentosaceus dpc6006 had the lowest fecal count at approximately 10(5) cfu/g and was excreted at a significantly lower level than both l. murin ... | 2004 | 15066778 |
| isolation and characterization of anti-salmonella lactic acid bacteria from the porcine gastrointestinal tract. | to identify lactic acid bacteria (lab) of porcine intestinal origin with anti-salmonella activity. | 2004 | 15482434 |
| purification and molecular characterization of antibacterial compounds produced by lactobacillus murinus strain l1. | the aim of this work was to purify and characterize antibacterial compounds produced by lactobacillus murinus strain l1. | 2005 | 16108807 |
| identification and antagonistic activity of lactic acid bacteria occurring in porcine blood from industrial slaughterhouses--a preliminary study. | ninety-seven lactic acid bacteria (lab) were isolated from slaughterhouse porcine blood in order to select autochthonous lab strains for use as biopreservatives of this by-product. they were identified by 16s rdna sequencing; and their inhibition capacity was determined against four bacterial species frequently found in contaminated blood, i.e. staphylococcus aureus, escherichia coli, pseudomonas fluorescens and bacillus spp. the taxonomic study showed an unexpected low diversity of lab in blood ... | 2006 | 16278029 |
| in vitro activity of potential probiotic lactobacillus murinus isolated from the dog. | the aim of this study was to isolate and identify lactobacillus spp. isolates from faeces of a healthy dog, and to characterize their potential as probiotics in order to evaluate their possible use as probiotics for dogs. | 2008 | 18194243 |
| predominance of a bacteriocin-producing lactobacillus salivarius component of a five-strain probiotic in the porcine ileum and effects on host immune phenotype. | relative predominance of each of five probiotic strains was investigated in the ileum of weaned pigs, compared with that in feces, when administered in combination at c. 5 x 10(9) cfu day(-1) for 28 days. probiotic was excreted at 10(6)-10(9) cfu g(-1) feces, while ileal survival ranged from 10(2) to 10(6) cfu g(-1) digesta. in contrast to the feces, where lactobacillus murinus dpc6002 predominated, the bacteriocin-producing lactobacillus salivarus dpc6005 dominated over coadministered strains b ... | 2008 | 18373687 |
| isolation of bacteria from mouse caecal samples and description of bacteroides sartorii sp. nov. | caecal samples from wild-type and tnf(deltaare) mice were cultured on selective media containing bile salts, amino acids or casein macro-peptides. twenty-two strains were isolated and identified by 16s rrna gene sequencing. twenty-one strains showed >98% similarity to known bacteria (blautia spp., clostridium innocuum, enterococcus spp., escherichia coli, lactobacillus murinus, parabacteroides goldsteinii and shigella dysenteriae). one additional isolate, strain a-c2-0, was a new bacterium. the ... | 2010 | 20369227 |
| gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the helicobacter pylori ins-gas mouse model of gastric carcinogenesis. | gastric colonisation with intestinal flora (if) has been shown to promote helicobacter pylori (hp)-associated gastric cancer. however, it is unknown if the mechanism involves colonisation with specific or diverse microbiota secondary to gastric atrophy. | 2013 | 23812323 |
| in vitro assessment of functional properties of lactic acid bacteria isolated from faecal microbiota of healthy dogs for potential use as probiotics. | lactic acid bacteria were isolated and identified in the faeces of chinese crested and yorkshire terrier pups and their probiotic features were investigated in vitro. thirty seven isolates were identified as lactobacillus or enterococcus. out of these isolates, 31 were lactic acid bacteria (lab) and belonged to the species lactobacillus reuteri (16/37; 43.3%), lactobacillus animalis (7/37; 18.9%), lactobacillus acidophilus (3/37; 8.1%), lactobacillus sanfranciscensis (2/37; 5.4%), lactobacillus ... | 2013 | 23538205 |
| survival of silage lactic acid bacteria in the goat gastrointestinal tract as determined by denaturing gradient gel electrophoresis. | to determine the survival rate of silage lactic acid bacteria (lab) in the ruminant gastrointestinal tract. | 2012 | 22925065 |
| spatial distribution and stability of the eight microbial species of the altered schaedler flora in the mouse gastrointestinal tract. | the overall complexity of the microbial communities in the gastrointestinal (gi) tracts of mammals has hindered observations of dynamics and interactions of individual bacterial populations. however, such information is crucial for understanding the diverse disease-causing and protective roles that gut microbiota play in their hosts. here, we determine the spatial distribution, interanimal variation, and persistence of bacteria in the most complex defined-flora (gnotobiotic) model system to date ... | 2004 | 15128534 |
| streptococcus alactolyticus is the dominating culturable lactic acid bacterium species in canine jejunum and feces of four fistulated dogs. | canine intestinal lactic acid bacterium (lab) population in four fistulated dogs was cultured and enumerated using mrs agar. lab levels ranging from 1.4x10(6) to 1.5x10(7) cfu ml(-1) were obtained in jejunal chyme. in the fecal samples 7.0x10(7) and 2.0x10(8) cfu g(-1) were detected. thirty randomly selected isolates growing in the highest sample dilutions were identified to species level using numerical analysis of 16s and 23s rdna restriction fragment length polymorphism patterns (ribotyping) ... | 2004 | 14734163 |
| comparison of the indigenous oral microbiota and immunoglobulin responses of athymic (nu/nu) and euthymic (nu/+) mice. | the role of the immune system in the homeostasis of indigenous oral bacterial populations is poorly understood. in this study, we compared the evolution of the indigenous oral microbiota of specific pathogen-free athymic nude (nu/nu) balb/c mice with that of their corresponding phenotypically normal (nu/-) littermates. we also evaluated corresponding salivary and serum antibody activities (iga and igg) against the predominant indigenous oral bacteria. the bacterial species recovered from the two ... | 1997 | 9467399 |
| kinetics of the establishment of gastrointestinal microflora in the conventional new-born rat. | the kinetics of the establishment of gastrointestinal flora in the conventional new-born rat aged 5 h to 8 days was studied. anaerobic species were counted by the method of hungate in an anaerobic glove box, in the stomach and the whole of the intestine. in both organs, staphylococci and micrococci were the first bacteria to settle, along with a few unidentified aerobic bacilli. counts levelled off after the first day. streptococci and enterococci settled somewhat later, and their numbers too le ... | 1982 | 7149529 |
| purification and properties of malolactic enzyme from lactobacillus murinus cnrz 313. | the malolactic enzyme of lactobacillus murinus was purified 79 fold. mr = 220,000 as determined by gel filtration and gradient gel electrophoresis. the enzyme consists of two apparently identical subunits (mr = 110,000) that were observed after treatment with sodium dodecyl sulfate. nad protected the enzyme against inactivation and its addition, after dissociation, restored the malolactic activity. the apparent km's for malate, nad, and mn2+ were 2.31 x 10(-2), 4.5 x 10(-4), and 1.4 x 10(-4) mm, ... | 1984 | 6536648 |
| d-(+)-lactate dehydrogenase from lactobacillus murinus. | d-(+)-lactate dehydrogenase from lactobacillus murinus was purified 670-fold. the mr was 140,000 as determined by gel filtration. maximum enzymatic activity was observed at 25 degrees c and ph 6.0 in 200 mm na2kpo4 buffer. when the temperature was increased from 60 to 65 degrees c, the enzyme was completely inactive in 5 min. the apparent km for pyruvate and nadh were 4.7 x 10(-4) and 1 x 10(-5) m, respectively. pyruvate analogs such as oxalate, oxamate, 2-oxobutyrate, and malonate acted as a co ... | 1986 | 3768146 |
| effect of cultivation conditions on proteinase production by lactobacillus murinus. | proteinase production by lactobacillus murinus was influenced by temperature, glucose concentration, initial ph and nitrogen sources. maximum proteinase production occurred at 45 degrees c, ph 6.6 and with 0.5% (w/v) glucose. tryptone, peptone and gelatin inhibited it. | 1987 | 3546030 |
| malolactic enzyme in lactobacillus murinus. | the malolactic enzyme of lactobacillus murinus is inducible. the induction is produced by l-malic acid only in the presence of glucose and amino acids and occurs at the transcription level. the enzyme, purified to homogeneity, has a mr of 220,000 and consists of 2 apparently identical subunits (mr = 110,000) that were observed after treatment with sodium dodecyl sulphate. nad+ protected the enzyme against inactivation and its addition, after dissociation, restored the malolactic activity. maximu ... | 1988 | 3139053 |
| role of bacteroides uniformis in susceptibility of ta:cf# 1 mice to infection by treponema hyodysenteriae. | among the various strains and colonies of mice tested specific-pathogen-free (spf) ta:cf#1 mice exhibited the highest susceptibility to treponema hyodysenteriae infection. staphylococcus epidermidis 1047, streptococcus faecalis 2039, lactobacillus murinus 3010, escherichia coli 1049, and bacteroides thetaiotaomicron 3008 were administered to the ta:cf#1 mice. b. uniformis ik, which appeared to colonize in the breeding facility under spf conditions, was isolated from the cecal content of a ta:cf# ... | 1990 | 2148089 |
| in vitro evaluation of the safety and probiotic properties of lactobacilli isolated from chicken and calves. | a total of 73 chicken and calves isolates were diagnosed using matrix-assisted laser desorption ionization-time-of flight mass spectrometry (maldi-tof ms). after a preliminary subtractive screening based on the high acid tolerance at ph 2.5 and bile resistance at 0.3% oxgall, twenty isolates belonging to the species lactobacillus salivarius, lactobacillus agilis, lactobacillus reuteri, lactobacillus murinus and lactobacillus amylovorus were in vitro screened for the safety assessment and probiot ... | 2014 | 24291759 |
| enhanced expression of fucosyl ga1 in the digestive tract of immune-deficient scid, nude and pigr(-/-) mice. | fucosylation of ga1 in murine intestinal epithelia occurs through transcriptional induction of α1,2-fucosyltransferase along with bacterial infection, but the mechanism has not been clearly characterized as to whether it is induced as a result of an immune response to bacteria or of genetic manipulation of the host by bacteria. accordingly, we analysed the expression of fucosyl ga1 (fga1) and fucosyltransferase activity in the digestive tracts of immune-deficient scid, nude and pigr(-/-) mice. i ... | 2013 | 24089533 |
| isolation and characterization of faecal bifidobacteria and lactobacilli isolated from dogs and primates. | although bifidobacteria and lactobacilli have been suggested beneficial for the host and are components of many probiotics and competitive exclusion mixtures, the knowledge on abundance, metabolic and probiotic characteristics in isolates from dogs and monkeys is still limited. the present study was aimed to isolate bifidobacterium and lactobacillus strains (faeces of 22 dogs and of 5 primates: cebus apella, eulemur fulvus, erythrocebus patas, macaca fascicularis, papio hamadryas) with the maldi ... | 2014 | 24239978 |
| prebiotic effect of diosgenin, an immunoactive steroidal sapogenin of the chinese yam. | this study investigated the effect of diosgenin, a yam-derived phytochemical, on the growth of enteric lactic acid bacteria (lab). the in vivo effect of diosgenin on the density of intestinal flora was examined in a murine model of food allergy. oral administration with diosgenin markedly restored the diminished density of faecal lab associated with allergic reactions. the direct effect of diosgenin and several structure-related steroidal compounds on the growth of faecal anaerobes isolated from ... | 2012 | 26434311 |
| bacterial colonization of the oral cavity of the balb/c mouse. | the acquisition of the human oral bacterial flora follows a relatively well known sequence of succession that can be influenced by various host factors. these factors have not been studied in the mouse. in the present work, we followed the bacterial colonization of the oral cavity of mice from birth, and tested our mouse model for its suitability in studying the influence of weaning and puberty on the indigenous oral bacterial flora. we observed that the first colonizers were staphylococci, foll ... | 1993 | 24190095 |
| oral colonization by streptococcus mutans and caries development is reduced upon deletion of carbonic anhydrase vi expression in saliva. | carbonic anhydrase vi (ca vi), encoded by type a transcripts of the gene car6, is a secretory product of salivary glands and is found in the enamel pellicle. because higher caries prevalence is associated with lower salivary concentrations of ca vi in humans, we tested whether ca vi protects enamel surfaces from caries induced by streptococcus mutans, using car6(-/-) mice, in which salivary ca vi expression is absent. we detected aberrant car6 type a transcripts in car6(-/-) mice, likely targets ... | 2011 | 21945428 |
| screening of lactic acid bacteria and bifidobacteria for potential probiotic use in iberian dry fermented sausages. | the purpose of this study was to select lactic acid bacteria and bifibobacteria strains as potential probiotic cultures during the processing of iberian dry fermented sausages. a total of 1000 strains were isolated from iberian dry fermented sausages (363), and human (337) and pig faeces (300) in different culture media. around 30% of these strains, mainly isolated from iberian dry fermented sausages in lamvab agar, were pre-selected for testing as potential probiotics by their ability to grow a ... | 2008 | 22063588 |
| identification and evaluation of the probiotic potential of lactobacilli isolated from canine milk. | canine milk protects puppies against infectious diseases through a variety of mechanisms. in this study, the presence of potentially probiotic lactic acid bacteria grown on mrs-cys agar plates from milk of nine bitches was investigated. the gram positive catalase negative bacilli identified in this study belonged to four lactobacillus species (lactobacillus reuteri, lactobacillus fermentum, lactobacillus murinus, lactobacillus animalis), as well as one isolate that was identified as weissella vi ... | 2010 | 19451012 |
| effect of obstructive jaundice and nitric oxide on the profiles of intestinal bacterial flora in wild and inos mice. | we previously reported that the plasma level of endotoxin and colonic expression of iga in the mouse increased with obstructive jaundice induced by bile duct ligation (bdl). to elucidate the mechanism of the bdl-induced increase, we analyzed the effect of bdl on intestinal flora in wild type and inducible nitric oxide synthase (inos)-deficient mice (inos(-/-)) using the terminal restriction fragment length polymorphism analysis (t-rflp) and 16s rdna clone libraries. the amounts of bacterial dna ... | 2009 | 19308270 |
| intranasal bacteria induce th1 but not treg or th2. | commensal microorganisms colonize the nasal mucosa without inducing inflammation. pathogens perturbing the commensal flora often invade evading immune defenses. the different types of adaptive responses that drive the distinct behaviors of commensals and pathogens, allowing one to persist at mucosal surfaces and the other to survive within tissues, are not yet clear. in the present work we demonstrate that although crossing epithelial barriers, the commensal lactobacillus murinus stimulates epit ... | 2009 | 19079337 |
| metabolic activity of probiotics-oxalate degradation. | urinary tract stones are an important clinical problem in human and veterinary medicine. hyperoxaluria is the single strongest promoter of kidney stone formation. the aims of the present study were to (a) evaluate oxalate degradation by a range of bifidobacteria species and lactobacillus species isolated from the canine and feline gastrointestinal tract in vitro and (b) to determine the impact of oxalate degradation by selected strains in vivo. the bacteria were grown in oxalate-containing media ... | 2009 | 19028028 |
| dietary supplementation with sorbitol results in selective enrichment of lactobacilli in rat intestine. | a potential prebiotic action has been ascribed to sorbitol, but in vivo evidence of this remains scarce. in the present work, the effect of sorbitol was compared to that of fructo-oligosaccharides (fos) in a rat model. microbiota changes, particularly in lactobacilli, were analyzed on fecal, colonic and cecal samples. denaturing gradient gel electrophoresis (dgge) analysis of 16s rrna gene amplicons using universal primers showed that fos and sorbitol diets exerted a strong influence upon gut mi ... | 2007 | 17825531 |
| lactobacillus plantarum for oral peptide delivery. | to evaluate strains of lactobacilli for their ability to persist and secrete heterologous protein in the oral cavity. | 2007 | 17311639 |
| a five-strain probiotic combination reduces pathogen shedding and alleviates disease signs in pigs challenged with salmonella enterica serovar typhimurium. | salmonella spp. infection is a major cause of gastroenteritis, with many thousands of cases reported in the european union every year. the use of probiotics offers the potential to improve this situation. here, we investigate the effects of oral treatment of pigs with a defined lactic acid bacteria culture mixture on both clinical and microbiological signs of salmonella enterica serovar typhimurium infection. fifteen weaned pigs blocked by sex and weight were administered control milk or a mixtu ... | 2007 | 17261517 |
| lactobacillus apodemi sp. nov., a tannase-producing species isolated from wild mouse faeces. | a gram-positive, rod-shaped, non-endospore-forming bacterium, strain asb1(t), able to degrade tannin, was isolated from faeces of the japanese large wood mouse, apodemus speciosus. comparative analysis of the 16s rrna gene sequence revealed that the strain could be assigned as a member of the genus lactobacillus. the nearest phylogenetic neighbours were determined as lactobacillus animalis dsm 20602(t) (98.9 % 16s rrna gene sequence similarity) and lactobacillus murinus asf 361 (98.9 %). subsequ ... | 2006 | 16825652 |
| preventive and therapeutic administration of an indigenous lactobacillus sp. strain against proteus mirabilis ascending urinary tract infection in a mouse model. | probiotics are increasingly being considered as non-pharmaceutical and safe potential alternatives for the treatment and prevention of a variety of pathologies including urinary tract infections. these are the most common infections in medical practice and are frequently treated with antibiotics, which have generated an intense selective pressure over bacterial populations. proteus mirabilis is a common cause of urinary tract infections in catheterised patients and people with abnormalities of t ... | 2005 | 15928974 |
| draft genome sequence of the murine bacterial isolate lactobacillus murinus ef-1. | screening for lysogenic lactobacilli in rat fecal samples has identified lactobacillus murinus ef-1. whole-genome sequencing revealed a 2.30-mb draft genome with 39.6% g+c content and 2,196 open reading frames. phast analysis identified three intact prophages of 26.1 kb, 25.4 kb, and 49.6 kb in size. | 2017 | 28336601 |
| inhibition of dectin-1 signaling ameliorates colitis by inducing lactobacillus-mediated regulatory t cell expansion in the intestine. | dectin-1, the receptor for β-glucans, protects the host against fungal infection; however, its role in intestinal immunity is incompletely understood. we found that dectin-1-deficient (clec7a(-/-)) mice were refractory to both dextran sodium sulfate (dss)- and cd45rb(high)cd4(+) t cell-induced colitis, and that this resistance was associated with an increase in regulatory t (treg) cells. the proportion of lactobacilli, especially lactobacillus murinus, in the commensal microflora was increased i ... | 2015 | 26269954 |
| bile tolerance and its effect on antibiotic susceptibility of probiotic lactobacillus candidates. | before use in practice, it is necessary to precisely identify and characterize a new probiotic candidate. eight animal lactobacilli and collection strain lactobacillus reuteri ccm 3625 were studied from the point of saccharide fermentation profiles, bile salt resistance, antibiogram profiles, and influence of bile on sensitivity to antibiotics. studied lactobacilli differed in their sugar fermentation ability determined by api 50chl and their identification based on these profiles did not corres ... | 2015 | 25413644 |
| analysis of the microbial ecology between helicobacter pylori and the gastric microbiota of mongolian gerbils. | animal models are essential for in vivo analysis of helicobacter-related diseases. mongolian gerbils are used frequently to study helicobacter pylori-induced gastritis and its consequences. the presence of some gastric microbiota with a suppressive effect on h. pylori suggests inhibitory gastric bacteria against h. pylori infection. the aim of the present study was to analyse the microbial ecology between h. pylori and the gastric microbiota of mongolian gerbils. gastric mucosa samples of h. pyl ... | 2014 | 24164959 |
| colonization of the mouse upper gastrointestinal tract by lactobacillus murinus: a histological, immunocytochemical, and ultrastructural study. | lactobacillus is normally present in animals and humans colonizing several epithelia, mainly those belonging to the upper gastrointestinal tract. most of the information about the distribution of lactobacillus in mice has been obtained by bacterial culture and characterization, and only few reports have described the direct presence of these bacteria in tissues, especially in the gastric mucosa. in this study, we have characterized and evaluated the location and detailed relationship between lac ... | 2013 | 23689939 |
| microbiota-derived lactate accelerates colon epithelial cell turnover in starvation-refed mice. | oral food intake influences the morphology and function of intestinal epithelial cells and maintains gastrointestinal cell turnover. however, how exactly these processes are regulated, particularly in the large intestine, remains unclear. here we identify microbiota-derived lactate as a major factor inducing enterocyte hyperproliferation in starvation-refed mice. using bromodeoxyuridine staining, we show that colonic epithelial cell turnover arrests during a 12- to 36-h period of starvation and ... | 2013 | 23552069 |
| intestinal dysbiosis and biotin deprivation induce alopecia through overgrowth of lactobacillus murinus in mice. | metabolism by the gut microbiota affects host physiology beyond the gastrointestinal tract. here, we find that antibiotic-induced dysbiosis, in particular, overgrowth of lactobacillus murinus (l. murinus), impaired gut metabolic function and led to the development of alopecia. while deprivation of dietary biotin per se did not affect skin physiology, its simultaneous treatment with vancomycin resulted in hair loss in specific pathogen-free (spf) mice. vancomycin treatment induced the accumulatio ... | 2017 | 28813664 |
| effect of milk fermented with lactic acid bacteria on diarrheal incidence, growth performance and microbiological and blood profiles of newborn dairy calves. | the effect of the administration of milk fermented with lactic acid bacteria to calves was evaluated. the strains included were: lactobacillus murinus crl1695, lact. mucosae crl1696, lact. johnsonii crl1693, and lact. salivarius crl1702, which were selected for their beneficial and functional properties and isolated from healthy calves in the northwestern region of argentina. the trial was conducted on a dairy farm located in tucumán (holando-argentino calves). a randomized controlled trial was ... | 2017 | 28770479 |
| effect of the probiotic lactobacillus murinus lbp2 on clinical parameters of dogs with distemper-associated diarrhea. | the objective of this study was to assess the effect of the probiotic lactobacillus murinus native strain (lbp2) on general clinical parameters of dogs with distemper-associated diarrhea. two groups of dogs over 60 d of age with distemper and diarrhea were used in the study, which was done at the animal hospital of the veterinary faculty of the university of uruguay, montevideo, uruguay. the dogs were treated orally each day for 5 d with the probiotic or with a placebo (vehicle without bacteria) ... | 2017 | 28408779 |
| [effect of mdg-1, a polysaccharide from ophiopogon japonicas, on diversity of lactobacillus in diet-induced obese mice]. | for understanding the effect of mdg-1, a water-soluble β-d-fructan polysaccharide from ophiopogon japonicas, on intestinal microecological balance, especially on the changes of lactobacillus, sixty 8-week-old male c57bl/6j mice were given a high-fat diet for six weeks and were also gavaged with saline once a day simultaneously. then the mice which is below 30 grams or dropped more than 10% through lavage were eliminated and the rest were randomly divided into four groups: diet-induced obese (dio ... | 2015 | 26137696 |
| absence of lactobacilli containing glycolipids with the α-galactose epitope and the enhanced fucosylation of a receptor glycolipid ga1 in the digestive tracts of immune-deficient scid mice. | the lactobacillus species in the digestive tracts of immune-deficient scid mice was distinct from that in control mice, i.e. lactobacillus murinus in scid and l. johnsonii in control mice, according to their 16s-rrna, indicating that a symbiotic relationship between lactobacilli and a host is established under pressure from the immune system. the caecal and colonal contents rich in l. murinus of scid mice were loose with a strong sour smell, resulting in diarrhoea, and those with l. johnsonii in ... | 2015 | 25759397 |
| production, purification and characterization of bacteriocin from lactobacillus murinus au06 and its broad antibacterial spectrum. | to study the production, purification and characterization of bacteriocin from lactobacillus murinus au06 isolated from marine sediments and its broad spectrum of inhibition against fish pathogens. | 2014 | 25183102 |
| effect of native lactobacillus murinus lbp2 administration on total fecal iga in healthy dogs. | the objective of the present work was to determine the effect of lactobacillus murinus strain lbp2 on canine fecal immunoglobulin a (iga) levels. seven dogs were orally treated with a 3-ml suspension of l. murinus lbp2 containing 5 × 10(9) colony-forming units on alternate days for 2 wk. six dogs were treated with 3 ml of phosphate-buffered saline as placebo. fecal samples were taken from the rectal ampulla on days 0 and 16, and the total canine fecal iga concentration was determined with an imm ... | 2014 | 24688179 |
| in vitro evaluation method for screening of candidate prebiotic foods. | the aim of this work was to develop a simple and rapid in vitro evaluation method for screening and discovery of uncharacterised and untapped prebiotic foods. using a nmr-based metabolomic approach coupled with multivariate statistical analysis, the metabolic profiles generated by intestinal microbiota after in vitro incubation with feces were examined. the viscous substances of japanese bunching onion (jbovs) were identified as one of the candidate prebiotic foods by this in vitro screening met ... | 2014 | 24444934 |
| differential colonization with segmented filamentous bacteria and lactobacillus murinus do not drive divergent development of diet-induced obesity in c57bl/6 mice. | alterations in the gut microbiota have been proposed to modify the development and maintenance of obesity and its sequelae. definition of underlying mechanisms has lagged, although the ability of commensal gut microbes to drive pathways involved in inflammation and metabolism has generated compelling, testable hypotheses. we studied c57bl/6 mice from two vendors that differ in their obesogenic response and in their colonization by specific members of the gut microbiota having well-described role ... | 2013 | 24049732 |
| lactobacillus faecis sp. nov., isolated from animal faeces. | three lactic acid bacteria were isolated from faeces of a jackal (canis mesomelas) and raccoons (procyron lotor). the isolates formed a subcluster in the lactobacillus salivarius phylogenetic group, closely related to lactobacillus animalis, lactobacillus apodemi and lactobacillus murinus, by phylogenetic analysis based on 16s rrna and reca gene sequences. levels of dna-dna relatedness revealed that the isolates belonged to the same taxon and were genetically separated from their phylogenetic re ... | 2013 | 23907223 |