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fatal endocarditis due to aerococcus urinae.aerococcus species are gram-positive cocci having gram-stain characteristics of staphylococci (i.e., form clusters), but biochemical and growth characteristics resembling streptococci and enterococci (i.e., catalase-negative, alpha-hemolytic growth on blood agar). a case of fatal endocarditis due to aerococcus urinae is presented. endocarditis should be suspected and, if confirmed, treated aggressively when a. urinae is recovered from blood cultures.19957554805
development of a polymerase chain reaction test for specific identification of the urinary tract pathogen aerococcus urinae.a polymerase chain reaction test was developed for identification of the gram-positive urinary tract pathogen aerococcus urinae. oligonucleotide primers were based on highly specific sequences within the small-subunit rrna gene. a confirmatory test based on hybridization of the amplified products to a highly specific internal probe was also developed.19937684752
septicaemia due to aerococcus urinae.in a case of septicaemia, aerococcus urinae was isolated from the blood. the patient had undergone operation on the prostate gland. the urine was sterile.19947747103
atmospheric growth requirements for alloiococcus species and related gram-positive cocci.the growth of alloiococcus otitis under different atmospheres and nutritional conditions was studied. the growth rates of 25 strains of gram-positive cocci representing five genera on heart infusion agar plates containing 5% rabbit blood and on brucella agar plates with and without sheep blood under aerobic, increased co2, and anaerobic atmospheres were compared. eight strains of alloiococci plated on heart infusion agar with rabbit blood and on brucella sheep blood agar grew under aerobic and c ...19968815077
septicaemia and endomyocarditis caused by aerococcus urinae.aerococcus urinae, an uncommon urinary tract pathogen, was recently shown to cause septicaemia and endocarditis in a few patients in denmark and the netherlands. in austria this is the first report of a fatal course of endomyocarditis by aerococcus urinae, associated with multiple septic infarcts.199910420497
three cases of serious infection caused by aerococcus urinae.three cases of serious infection caused by aerococcus urinae are presented: a patient with endocarditis and two patients with soft-tissue infection (phlegmon and balanitis respectively). the literature on aerococcus urinae infections is reviewed and the antibiotic therapy discussed. aerococcus urinae is a pathogen isolated primarily from urine specimens of elderly patients with local or systemic predisposing conditions. most infections are mild, but serious infections such as endocarditis and se ...199910421047
aerococcus urinae in urinary tract infections.aerococcus urinae is a rarely reported pathogen, possibly due to difficulties in the identification of the organism. a. urinae is a gram-positive coccus that grows in pairs and clusters, produces alpha-hemolysis on blood agar, and is negative for catalase and pyrrolidonyl aminopeptidase. some of these characteristics and its being absent from the databases of most commercial identification systems could allow a. urinae to be misidentified as a streptococcus, enterococcus, or staphylococcus. we r ...200010747177
[aerococcus urinae. a newcomer among pathogenic bacteria in clinical and microbiological practice].a decade ago we discovered a hitherto unrecognized aerococcus-like organism (alo) in urine specimens from patients with urinary tract infection. further microbiological and clinical investigations enabled us to classify it as a human pathogen also causing urogenic septicaemia and endocarditis, the latter often with lethal outcome. the organism is now designated aerococcus urinae.199910778337
[aerococcus urinae and urinary tract infection].bacteriological investigation of urine often shows the presence of alpha-haemolytic streptococci, but the clinical significance of this finding may be unclear. among the alpha-haemolytic streptococci found in urine is aerococcus urinae, which is pathogenic.200211873573
aerococcus urinae endocarditis: case report and review of the literature.aerococcus urinae is a rare cause of urinary tract infections, mainly in elderly men with underlying urinary tract pathologies. in addition, it has been described as a pathogen in balanitis, soft tissue infections, septicemia and endocarditis. to date ten cases of a. urinae endocarditis have been reported in the literature with a high rate of mortality (7/10) and morbidity, as two out of three survivors suffered from neurovascular complications. here we present the case of an additional patient ...200212382093
[hemopericardium caused by endocarditis ulcerosa: an unusual cause of sudden death in adolescence].the authors report on the case of a 18-year-old student who died suddenly and unexpectedly of a pericardial tamponade after perforated ulcer-polypous endocarditis of the aortic valve. the detection of aerococcus urinae--which usually causes urinary tract infection--on the inflamed aortic valve demonstrates an unusual pathogenetic chain linking complexes of findings in the urogenital system and the heart.200212532678
lymphadenitis caused by aerococcus urinae infection.aerococcus urinae is rarely reported as a human pathogen. the pathogenesis of this gram-positive coccus is not fully understood. it has been identified as a cause of urinary tract infections but may be associated with severe infections such as endocarditis and septicaemia. this paper presents a case of lymphadenitis caused by a. urinae.200312875530
identification of aerococcus urinae in urine samples.to evaluate procedures for the identification of aerococcus urinae, we examined 24 alpha-hemolytic non-enterococcal bacterial isolates from 4373 urine samples. published procedures were compared with 16s rrna sequencing and biochemical profiling (bbl-crystal-gp). 16s rrna sequencing and bbl-crystal-gp identified the same 13 isolates as a. urinae. published tests failed to distinguish the 13 a. urinae isolates from eight non-a. urinae isolates; several tests exhibited no discrimination. ciproflox ...200314616691
spondylodiscitis due to aerococcus urinae: a first report.aerococcus urinae is an uncommon urinary tract pathogen which causes infections predominantly in elderly persons with local and general predisposing conditions. there are few case reports of severe infections caused by aerococcus urinae among which only 14 cases of endocarditis caused by aerococcus urinae have been reported. we report the first case of aerococcus urinae spondylodiscitis. the patient responded to 4 weeks of amoxicillin and clindamycin, and to 5 months of amoxicillin alone.200314723372
urosepsis with actinobaculum schaalii and aerococcus urinae.actinobaculum was isolated from urine only after prolonged incubation in 5% co(2) after discrepancy between urine gram stain and initial culture results was observed. additional patients were diagnosed using this method. the prevalence of actinobaculum species in urinary tract infections is underestimated since it is not isolated by routine urine culture procedures.200616455938
culture-negative infective endocarditis caused by aerococcus urinae.aerococcus urinae is a rarely reported pathogen that often causes mild urinary tract infection (uti), although serious complications such as endocarditis and septicemia have also been described. the organism may easily be missed or misidentified when using commercial detection systems. a. urinae is resistant to sulfonamides and, therefore, a typical treatment for uti may be inappropriate. to date, 14 cases of a. urinae infective endocarditis (ie) have been reported, most of which were elderly ma ...200717484472
acute pyelonephritis caused by aerococcus urinae in a 12-year-old boy.aerococcus urinae are gram-positive cocci that cause urinary tract infections in adults with underlying genitourinary (gu) tract disease. we report a case of pyelonephritis caused by a. urinae in a 12-year-old boy with a history of pyeloplasty and gu reflux.200818574434
fatal infective endocarditis due to aerococcus urinae--case report and review of literature.aerococcus-related infective endocarditis is a rare form of endocarditis with a high mortality. most cases have associated genitourinary system pathology. aerococcus urinae is a gram-positive coccus that is arranged in clusters resembling staphylococcus, but its growth characteristics and colonial morphology are closer to that of an alpha-hemolytic streptococcus. this organism may initially be dismissed as a contaminant in clinical cultures from nonsterile sites. we report a representative case ...200818692408
aerococcus urinae in bovine reproductive disease. 200818931362
aerococcus urinae in ovine reproductive disease. 200819011254
association of streptococcus pluranimalium with valvular endocarditis and septicaemia in adult broiler parents.the genus streptococcus consists of more than 60 species, but only streptococcus equi subspecies zooepidemicus, streptococcus gallolyticus ssp. gallolyticus, streptococcus gallinaceus, streptococcus dysgalactiae, streptococcus mutans and streptococcus suis have been isolated from poultry. during investigations of the aetiology of increased mortality in broiler parent stock at the end of production, pure cultures of streptococcal-like organisms that could not be classified among these six species ...200919322715
extracorporeal support in a patient with cardiogenic shock due to aerococcus urinae endocarditis.aerococcus urinae is a newly identified gram-positive coccus that causes serious infections. to date, only 15 cases of a. urinae infective endocarditis have been reported, but with a very high mortality. the case is reported of a patient with a. urinae double valve endocarditis. following aortic and mitral valve replacement, the patient suffered from refractory cardiogenic shock; extracorporeal membrane oxygenation was used successfully as a rescue mechanical support.200919852146
a case of endocarditis due to aerococcus urinae. 201020369517
aerococcus urinae and aerococcus sanguinicola, two frequently misidentified uropathogens.species belonging to the aerococcus genus are isolated from the urine and blood of elderly patients suffering from urinary tract infections (utis). however, the clinical significance, phenotypic features and antimicrobial susceptibilities of these underestimated and/or misidentified species remain unclear. from march 2006 to november 2008, among 350 non-enterococcal streptococcaceae species isolated from urinary specimens, 30 (8.6%) aerococcus spp. strains were recovered. all strains were charac ...201020482457
aerococcus urinae: severe and fatal bloodstream infections and endocarditis.aerococcus urinae is a pathogen that rarely causes severe or fatal infections. we describe four cases of severe a. urinae bloodstream infections. all patients had underlying urologic conditions. urine cultures, however, were negative.201020660216
platelet activation and biofilm formation by aerococcus urinae, an endocarditis-causing pathogen.the gram-positive bacterium aerococcus urinae can cause infectious endocarditis (ie) in older persons. biofilm formation and platelet aggregation are believed to contribute to bacterial virulence in ie. five a. urinae isolates from human blood were shown to form biofilms in vitro, and biofilm formation was enhanced by the presence of human plasma. four of the a. urinae isolates caused platelet aggregation in platelet-rich plasma from healthy donors. the au3 isolate, which induced platelet aggreg ...201020696834
a case report of successful management of aerococcus urinae peritonitis in a patient on peritoneal dialysis. 201021148062
phenotypic characterisation and 16s rrna sequence analysis of veterinary isolates of streptococcus pluranimalium.forty-two isolates of streptococcus pluranimalium were identified from cattle (n=38), sheep (n=2), an alpaca (n=1) and a pheasant (n=1) in the united kingdom. the isolates were confirmed as s.pluranimalium by 16s rrna sequence analysis but could not be differentiated reliably from streptococcus acidominimus by phenotypic characterisation using commercial kits routinely used in veterinary laboratories. the alanyl-phenylalanyl-proline arylamidase reaction could be used to differentiate s. pluranim ...201121703886
aerococcus urinae and trimethoprim-sulfamethoxazole.aerococcus urinae has been described as resistant to trimethoprim-sulfamethoxazole (sxt), but the test medium may affect this observation. twenty-seven clinical isolates of a. urinae tested susceptible to sxt in cation-adjusted mueller-hinton broth (camhb) plus lysed horse blood and resistant in camhb plus lysed sheep blood.201121918023
aerococci and aerococcal infections.aerococcus is a genus that comprises seven species, of which aerococcus urinae, and aerococcus sanguinicola are emerging human pathogens. aerococci are gram positive cocci that are easily misidentified as streptococci or staphylococci, and thus the incidence of aerococcal infections has been underestimated. with the introduction of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (maldi-tof ms) clinical microbiologists now have access to a rapid and accurate method to ...201223277106
[aerococcus urinae infective endocarditis.] 201121794855
a population-based study of aerococcal bacteraemia in the maldi-tof ms-era.the purpose of this study was to determine the incidence of aerococcal bacteraemia in the maldi-tof ms-era, to describe the clinical presentation and to determine the mic values of aerococci for ten antibiotics. aerococci in blood cultures were identified through searches in the laboratory database for the years 2012-2014. maldi-tof ms, sequencing of the 16s rrna gene and a pyr test were used for species identification. patients' medical charts were systematically reviewed. etests were used to d ...201626838685
aerococcus vaginalis sp. nov., isolated from the vaginal mucosa of a beef cow, and emended descriptions of aerococcus suis, aerococcus viridans, aerococcus urinaeequi, aerococcus urinaehominis, aerococcus urinae, aerococcus christensenii and aerococcus sanguinicola.a gram-stain-positive, facultatively anaerobic, non-spore-forming, catalase-negative, coccoid-shaped bacterial strain, designated bv2(t), was isolated from the vaginal mucosa of a beef cow in japan. phylogenetic analysis showed that the isolate shared high 16s rrna gene sequence similarity (92.9 %) with aerococcus suis 1821/02(t) and low similarity (<92.7 %) with any other recognized species of the genus aerococcus. the dna g+c content was 44.7 mol%, which is within the range observed among spec ...201424421273
rapid paper disk test for identification of helicobacter pylori in mixed cultures of gerbil gastric homogenates.a method denominated rapid paper disk test (rpdt) was developed to identify h. pylori colonies in complex cultures obtained from gerbil gastric homogenates. identification is based on a characteristic reaction pattern (rp) for h. pylori colonies given by the combination of the urease-oxidase activities on a paper disk. compared to the rps obtained from gerbil's intestinal tract isolated bacteria, h. pylori rp is completely distinguishable, even from those of bacteria that share one or both activ ...201020624429
[aerococcus urinae endocarditis: first case report in belgium and review of the literature].aerococcus urinae is a rarely reported pathogen, possibly due to difficulties in the identification of the organism. only sixteen cases of a. urinae endocarditis have yet been described. generally, patients were males with predisposing conditions and the outcomes were bad. we describe the first belgian case of endocarditis due to a. urinae. which occurred to a 79-year-old female patient. the diagnostic of a. urinae endocarditis was based on the cardiac ultrasonography and the isolation of the ba ...200819202713
three cases of serious infection caused by aerococcus urinae: a patient with spontaneous bacterial peritonitis and two patients with bacteremia. 200818463786
case study: aerococcus urinae as pathogen in peritoneal dialysis peritonitis--a first report. 200717984441
the resident microflora of voided midstream urine of healthy controls: standard versus expanded urine culture protocols.the workup and interpretation of urine cultures is not always clear-cut, especially for midstream samples contaminated with commensals. standard urine culture (suc) protocols are designed in favor of growth of uropathogens at the expense of commensals. in selected clinical situations, however, it is essential to trace fastidious or new uropathogens by expanding the urine culture conditions (euc). the aim of our study was to map the microflora in midstream urine specimens from healthy controls by ...201727844263
[neonatal bacteremia--frequency, spectrum of organisms and correlation between clinical symptoms and laboratory data for early onset sepsis].improved obstetrical management and evidence-based peripartum antimicrobial therapy in the last decades reduce the frequency of early-onset neonatal sepsis (eons) and improve the outcome. the spectrum of the microrganisms is different according to regions, countries and periods of time. appropriate diagnosis and treatment improve the outcome. however dissociation often occurs between clinical manifestation, laboratory and microbiological findings.201425098106
infective endocarditis and spondylodiscitis in a patient due to aerococcus urinae: first report. 200716766062
clinical significance of aerococcus urinae: a retrospective review.a retrospective chart review was performed on 54 patients with positive urine cultures during a 1-year period to assess the clinical significance of aerococcus urinae. based on predetermined criteria, patients were classified into 2 groups: those with urinary tract infections (utis) and those who were considered colonized. the majority of the patients were > or =65 years old and were female. only 31% of patients with uti and 45% of colonized patients had a. urinae isolated in pure cultures. both ...200516269223
a case of aerococcus urinae septicemia: an unusual presentation and severe disease course. 200516117890
aerococcus urinae: polyphasic characterization of the species.a polyphasic characterization of aerococcus urinae is presented. in this study the intraspecies relationships between 26 strains of varying geographical origin were examined by phenotypic tests, ribotyping and multilocus enzyme electrophoresis. the results demonstrated two main phenotypic patterns that could be distinguished in tests for hydrolysis of aesculin, and acid production from amygdalin and salicin. strains were either negative (n=19) or positive (n=6) in these tests. one strain had a d ...200516086822
phenotypic description and antimicrobial susceptibilities of aerococcus sanguinicola isolates from human clinical samples.this report describes the clinical sources and phenotypic characterization of 16 isolates of aerococcus sanguinicola. sixteen conventional tests were used to describe and differentiate the 16 isolates of a. sanguinicola from 30 strains of aerococcus viridans, 27 strains of aerococcus urinae, and a single strain each of aerococcus christensenii and aerococcus urinaehominis. the phenotypic characterizations of the type strains for each species and 14 a. sanguinicola isolates were also compared in ...200312791884
[urinary infection by aerococcus urinae]. 200312765596
in vitro antimicrobial susceptibility of aerococcus urinae to 14 antibiotics, and time-kill curves for penicillin, gentamicin and vancomycin.aerococcus urinae is a newcomer in clinical and microbiological practice, causing urinary tract infections, bacteraemia/septicaemia and/or endocarditis. this study presents for the first time an evaluation of the activity of a representative panel of antibiotics against a large number of a. urinae isolates. the in vitro susceptibilities (mics) of 56 isolates of a. urinae to 14 antibiotics were determined by agar dilution. in general, a. urinae isolates showed little inter-isolate variability, an ...200111679554
aerococcus urinae, a cause of cystitis with malodorous urine in a child: clinical and microbiological challenges.introduction. an infection of the lower urinary tract associated with an extremely unpleasant odour due to aerococcus urinae in an otherwise healthy 5-year-old boy is described herein. case presentation. interestingly, imaging examination revealed the presence of a bladder diverticulum. routine microbiological examination based on gram staining, colony morphology and catalase reactivity suggested that the responsible pathogen could belong either to staphylococci, α-haemolytic streptococci or ent ...201728348806
a rare case of perineal abscess caused by aerococcus urinae.aerococcus urinae, a previously misidentified pathogen, has become increasingly recognized to cause severe and even fatal infections. aerococcus-related perineal abscess infections have not previously been reported in the literature. most reported cases of infections caused by aerococcus are urinary tract infections, bacteremia, and even rare cases of endocarditis. we report an unusual case of a perineal abscess caused by aerococcus urinae.201728105405
comment on: a case of aerococcus urinae vertebral osteomyelitis. 201727942196
right coronary artery septic embolization secondary to aerococcus urinae native mitral valve endocarditis.septic embolization to the coronary arteries from infective endocarditis is a rare occurrence. appropriate treatment is not yet fully determined. we report a case of mitral valve endocarditis due to aerococcus urinae presenting as acute inferior myocardial infarction.201627645966
aerococcus urinaehominis sp. nov., isolated from human urine.phenotypic and phylogenetic studies were performed on an unknown gram-positive catalase-negative coccus isolated from human urine. comparative 16s rrna gene sequencing demonstrated that the organism represents a new subline within the genus aerococcus. the unknown bacterium was readily distinguished from the three currently recognized aerococcus species, aerococcus christensenii, aerococcus urinae and aerococcus viridans, by biochemical tests and electrophoretic analysis of whole-cell proteins. ...200111321115
aerococcus sanguicola sp. nov., isolated from a human clinical source.phenotypic and phylogenetic studies were performed on an unknown, gram-positive, catalase-negative coccus isolated from human blood. comparative 16s rrna gene sequencing demonstrated that the organism represents a new subline within the genus aerococcus. the unknown bacterium was readily distinguished from the three currently recognized aerococcus species, aerococcus christensenii, aerococcus urinae and aerococcus viridans, by biochemical tests and electrophoretic analysis of whole-cell proteins ...200111321093
aerococcus christensenii sp. nov., from the human vagina.phenotypic and phylogenetic studies were performed on two strains of a hitherto undescribed aerococcus-like organism isolated from the human vagina. comparative 16s rrna gene sequencing studies demonstrated that the unknown strains constitute a new subline within the genus aerococcus. the unknown bacterium was readily distinguished from the two currently recognized aerococcus species, aerococcus viridans and aerococcus urinae, by biochemical tests and electrophoretic analysis of whole-cell prote ...199910425770
clonal analysis of aerococcus urinae isolates by using the repetitive extragenic palindromic pcr (rep-pcr). 201626620045
diagnosis of aerococcus urinae infections: importance of matrix-assisted laser desorption ionization time-of-flight mass spectrometry and broad-range 16s rdna pcr. 201626363405
comment on "necrotizing urethritis due to aerococcus urinae". 201526356421
endocarditis due to aerococcus urinae: diagnostic tests, fatty acid composition and killing kinetics.two cases of aerococcus urinae endocarditis are reported. the organism is not included in any database of commercial identification systems at this time. formation of tetrades and positive reactions for leucine arylamidase and beta-glucuronidase pointed strongly to a. urinae. the cellular fatty acid pattern was similar to that of aerococcus viridans, with predominantly c16:0, c18:1 omega 9c and c18:0; the presence of c18:1 omega 7t differentiated our isolates from a. viridans and can support the ...199910219643
urinary tract infections with aerococcus urinae in the south of the netherlands.aerococcus urinae is an uncommon urinary tract pathogen that causes infections predominantly in elderly persons with local or general predisposing conditions. during a one-year study, the clinical features of aerococcus urinae urinary tract infections (> or = 10(5) cfu/ml) were investigated in two large medical microbiology laboratories in the netherlands. the incidence of aerococcus urinae urinary tract infections ranged between 0.31 and 0.44% for the two laboratories. the median age (range 35- ...19979495666
in vitro susceptibility of aerococcus urinae isolates to antibiotics used for uncomplicated urinary tract infection. 201525912613
first case of pregnant women bacteraemia and probable early-onset neonatal infection due to aerococcus urinae. 201525755882
in vitro activity of clinically implemented β-lactams against aerococcus urinae: presence of non-susceptible isolates in switzerland.we analyzed the in vitro susceptibility to several ?-lactams and vancomycin of 80 aerococcus urinae isolates collected during 2011-2012 in switzerland. mics were determined by etest (biomérieux) on müller-hinton agar with 5% sheep blood and interpreted according to the clsi and eucast criteria set for viridans streptococci. mic50/90 for penicillin, amoxicillin, ceftriaxone and vancomycin were 0.016/0.064 mg/l, 0.032/0.064 mg/l, 0.125/0.5 mg/l and 0.38/0.5 mg/l, respectively. three (3.8%) isolate ...201425387295
[urinary tract infection due to aerococcus urinae]. 201425282147
infectious endocarditis in 49-year-old man and discussion of phenotypic characteristics of aerococcus urinae and viridans streptococci.49 year-old man.201425135044
aerococcus urinae: intraspecies genetic and phenotypic relatedness.a number of aerococcus-like organisms were recently recognized as human pathogens. five aerococcus-like strains were proposed as members of the new species aerococcus urinae (with type strain e2 [= nctc 12142]) on the basis of the results of a 16s rrna sequence analysis. the intraspecies phenotypic and genetic relatedness of 22 selected a. urinae strains was investigated, and a hitherto unrecognized esculin hydrolysis-positive biotype was identified. a total of 14 of the 15 more common esculin-n ...19978995798
endocarditis caused by aerococcus urinae, a newly recognized pathogen.aerococcus urinae is a newly described pathogen. a case of aerococcus urinae endocarditis is presented, the primary focus being a urinary tract infection. the diagnosis of endocarditis was supported by isolation of aerococcus urinae from blood as well as from heart vegetations.19957729454
phylogenetic analysis of some aerococcus-like organisms from urinary tract infections: description of aerococcus urinae sp. nov.partial 16s ribosomal ribonucleic acid sequences of five aerococcus-like organisms originally isolated from patients with urinary tract infections were determined using reverse transcriptase in order to clarify their taxonomic position. analysis of the sequence data revealed that the clinical isolates represent a hitherto unknown line of descent within the genus aerococcus. a new species, aerococcus urinae, is proposed for these isolates. the type strain is ncfb 2893.19921373437
a second case of foul smelling urine in a boy caused by aerococcus urinae. 201324141805
hip abscess due to aerococcus urinae in a man with paraplegia: case report.single case report.201324042994
foul smelling urine in a 7-year-old boy caused by aerococcus urinae. 201223188102
complete genome sequences of aerococcus christensenii ccug 28831t, aerococcus sanguinicola ccug 43001t, aerococcus urinae ccug 36881t, aerococcus urinaeequi ccug 28094t, aerococcus urinaehominis ccug 42038 bt, and aerococcus viridans ccug 4311t.strains belonging to the genus aerococcus are causative agents of human and animal infections, including urogenital infections, bacteremia/septicemia, and infective endocarditis. this study reports the first fully closed and complete genome sequences of six type strains belonging to the genus aerococcus using a combination of illumina hiseq and pacbio sequencing technologies.201627103727
[a case of infective aerococcus urinae endocarditis successfully treated by aortic valve replacement].aerococcus urinae is a endocarditis rare causative organism with low virulene. we report an a. urinae endocarditis case treated by aortic valve replacement. an 80-year-old woman hospitalized for urinary tract infection and hydronephrosis due to three-week renal calculi. blood culture on admission isolated streptococcus acidominimus. during the course, she was transferred to our care for surgical intervention after developing congestive heart failure due to severe aortic regurgitation. echocardio ...201122250461
Clinical and microbiological features of bacteraemia with Aerococcus urinae.Clin Microbiol Infect ABSTRACT: Aerococcus urinae is a Gram-positive bacterium that can cause invasive infection, including infectious endocarditis (IE), mainly in older men. A. urinae is often misclassified in routine diagnostic laboratories. Through searches in the laboratory databases we identify 16 isolates of A. urinae causing bacteraemia during a 6-year period in southern Sweden, indicating that bacteraemia with A. urinae occurs in at least three cases per million inhabitants per year. The ...201121895858
culture-negative infective endocarditis of the aortic valve due to aerococcus urinae: a rare aetiology.bacteria of the species aerococcus urinae are gram-positive, catalase-negative cocci that are arranged in pairs, tetrads, or clusters resembling enterococci or staphylococci. they are rare causative agents of infective endocarditis. repetitive urinary tract infections based upon underlying genitourinary tract abnormalities could involve these bacteria. due to their similarity to other gram-positive cocci misinterpretation may occur along the line of microbiologic differentiation, which could pot ...201121889909
clinical significance and antimicrobial susceptibilities of aerococcus sanguinicola and aerococcus urinae.a retrospective chart review was performed on 92 patients from whom 118 isolates of aerococcus sanguinicola (n = 52) or aerococcus urinae (n = 66) were obtained from urine cultures between october 2007 and june 2008 to assess clinical presentation and antimicrobial susceptibilities. the mean patient age was 82 (range 24-101) years. the majority was female (76% and 87% for a. sanguinicola and a. urinae, respectively) and institutionalized (61% and 60%, respectively). the majority of male patients ...201121767701
aerococcus: an increasingly acknowledged human pathogen.aerococci have often been misidentified as streptococci in microbiology laboratories, leading to an underestimation of these bacteria as causes of human infections. an increased awareness of aerococci and the introduction of matrix-assisted laser desorption ionization time-of-flight mass spectrometry, has led to an increased isolation of aerococcus urinae and aerococcus sanguinicola from human urine and blood. the two species are found in human urine and can cause urinary tract infections (uti). ...201626454061
clinical and microbiological features of infective endocarditis caused by aerococci.to define the clinical presentation of aerococcal infective endocarditis (ie) and the prevalence of synergy between penicillin and gentamicin on aerococcal isolates.201626119199
epidemiology and antibiotic susceptibility of aerococci in urinary cultures.in this study, we present population-based data regarding the prevalence of aerococci in clinical urinary samples. during a 3-month period, all aerococcal isolates from urinary samples from 2 clinical microbiology laboratories were collected. we identified 64 aerococcus urinae isolates and 40 aerococcus sanguinicola isolates, which correlates with an incidence of 33 cases of aerococcal bacteriuria per 100,000 inhabitants per year. the median age was 83years for all patients with aerococcal bacte ...201525497460
aerococcus viridans: a rare pathogen causing urinary tract infection.aerococci are gram-positive cocci with colony morphology similar to viridans streptococci. most often these isolates in clinical samples are misidentified and considered insignificant. however, with the use newer techniques like matrix-assisted laser desorption ionization time-of-flight mass-spectrometry (maldi-tof ms), aerococci have been recognized as significant human pathogens capable of causing a diverse spectrum of infections. among the different species of aerococci, aerococcus urinae is ...201728273968
a case of sepsis in a 92-year-old korean woman caused by aerococcus urinae and identified by sequencing the 16s ribosomal rna gene.aerococcus urinae is an uncommon pathogen that was first identified in 1992. herein, we report a case of bloodstream infection caused by a. urinae, which occurred in a 92-year-old korean female patient with an underlying urologic infection who had altered consciousness. the blood culture yielded positive results for a. urinae; however, identifying a. urinae was challenging. ultimately, we used 16s ribosomal rna (rrna) gene sequencing to identify the organism. the patient recovered after being tr ...201626868516
[detection of unusual uropathogens during a period of three years in a regional hospital].urinary tract infections (utis) are one of the most frequent both in the community and in hospitals infectious diseases. the etiology of urinary tract infections is well established but may vary depending on various factors such as age, the presence of underlying diseases such as diabetes, instrumental procedures such as urinary catheterization or exposure to antibiotics or previous hospitalizations. utis diagnosed cases were retrospectively reviewed for unusual microorganisms over a period of 3 ...201525904515
a rare case of aerococcus urinae infective endocarditis.introduction:aerococcus urinae is a rare cause of infective endocarditis. aerococcus is a gram positive cocci that is easily misidentified as staphylococci or streptococci. the true incidence rate of this pathogen is likely underestimated. recent advances in laboratory diagnostic methods with matrix-associated laser desorption ionization time-of-flight mass spectrometry (maldi-tof-ms) have lead to increased recognition of this pathogen in the clinical microbiology lab, and awareness as a cause o ...201728638578
maldi-tof-ms fingerprinting provides evidence of urosepsis caused by aerococcus urinae.urosepsis due to aerococcus urinae is rare in clinical settings with only a few of reported cases worldwide by 16s rrna sequencing. here we report a case of sepsis caused by a. urinae in a 86 year-old male with complicated urinary tract infection which was confirmed through peptide mass fingerprinting of matrix-assisted laser desorption ionization time of flight mass spectrometry.201728608657
an initially unidentified case of urinary tract infection due to aerococcus urinae.aerococcus urinae is a microorganism responsible for urinary tract and blood stream infections which are rarely reported in clinical practice. however, it has been proposed that the infrequency of such reports may be partially due to difficulties related to pathogen identification. we present here a case of an elderly male patient with urinary tract infection where a. urinae was initially not identified by a private microbiology laboratory. our report highlights the need to consider a. urinae as ...201728513811
aerococcus urinae: an emerging cause of urinary tract infection in older adults with multimorbidity and urologic cancer.aerococcus urinae is a rare organism isolated from urine cultures. we present a case of an 80 year-old male with bladder cancer and multimorbidity who developed a. urinae infection. a. urinae may cause simple and complicated utis, bacteremia, and endocarditis in older adults with multimorbidity, chronic urinary retention, or indwelling catheters. a. urinae treatment should employ penicillin, amoxicillin, and nitrofurantoin. due to increasing antibiotic resistance, urine culture should include an ...201728435789
spondylodiscitis due to aerococcus urinae infection in an elderly immunocompetent patient. 201728372876
bactericidal activity of penicillin, ceftriaxone, gentamicin and daptomycin alone and in combination against aerococcus urinae.aerococcus urinae can cause severe infections (bacteraemia and endocarditis) that are associated with high mortality. however, data on the bactericidal and synergistic activity for clinically implemented antibiotics are scarce. time-kill analyses were performed on two clinical isolates (au1 and au2) and the reference strain atcc 700306 for penicillin (pg), ceftriaxone (cro), gentamicin (gen), daptomycin (dap) and their combinations. au1 and au2 were cro-resistant (mics, 2 µg/ml) and atcc 700306 ...201627451085
aerococcus urinae, a rare cause of infective endocarditis.we present the case of an elderly male who was initially seen in our hospital for a urinary tract infection that was treated with oral ciprofloxacin. he was admitted 2 weeks later with altered mental status and fever, and was found to have bacteraemia with aerococcus urinae owing to altered mental status a brain mri was performed which showed evidence of embolic stroke. following this, a transesophageal echocardiogram showed severe mitral regurgitation and a vegetation >1 cm involving the mitral ...201627440847
aerococcus urinae associated aortic and tricuspid valve infective endocarditis.aerococcus urinae is a rare bacteria usually associated with urinary tract infection. it is unusually associated with endocarditis. to date only 18 cases have been reported. among these cases, the majority had aortic valve involvement. three had mitral and aortic valve involvement, and two had mitral and tricuspid valve involvement. we present the first reported case of a. urinae associated aortic and tricuspid valve endocarditis. timely recognition and appropriate treatment of this fatal infect ...201627051583
necrotizing urethritis due to aerococcus urinae.a 49-year-old male presented to the emergency with hematuria and pain in the shaft of the penis for one day. the patient was found to be in a state of shock. the shaft of the penis and the scrotum were swollen and tender. no skin necrosis was observed and no crepitus was palpable. serum white count (wbc) was 29.5 × 10(3)/μl. a ct scan showed gas in the corpus spongiosum. antibiotics were started with iv metronidazole, vancomycin, and piperacillin/tazobactam. metronidazole was then replaced by cl ...201526171271
a case of aerococcus urinae vertebral osteomyelitis.aerococcus urinae is an aerobic, alpha hemolytic gram positive coccus bacterium that grows in pairs or clusters. we report the first case of vertebral osteomyelitis due to a. urinae. this has not been previously reported in the literature.201726069429
aerococcus urinae: a possible reason for malodorous urine in otherwise healthy children.recently, aerococcus urinae, primarily recognized as a common pathogen in elderly women, has been reported to cause an extremely unpleasant odour of the urine in paediatric patients similar to trimethylaminuria (fish odour syndrome). herein, we present a case of a. urinae urinary tract colonization in a 12-year-old otherwise healthy boy, who finally refused micturition outside from his home environment as a result of the unpleasant odour. within the last year, three cases (including our own) of ...201424913181
in vitro antimicrobial susceptibility of aerococcus urinae.aerococcus urinae may cause urinary tract infections, bacteremia, and endocarditis. no standardized susceptibility test methods or interpretive criteria have been proposed for this organism. this study reports the mic results for 128 a. urinae isolates tested by broth microdilution. the isolates had low mics to amoxicillin, cefotaxime, ceftriaxone, doxycycline, linezolid, meropenem, penicillin, rifampin, tetracycline, trimethoprim-sulfamethoxazole, and vancomycin. however, 55% of the isolates ha ...201424671781
prevalence and characteristics of fluoroquinolone-resistant aerococcus urinae isolates detected in switzerland. 201424630307
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