| aerobic bacterial flora of the prepuce, urethra, and vagina of normal adult dogs. | staphylococcus aureus and mycoplasma spp were the most frequently isolated aerobic microorganisms in specimens obtained from the prepuce and the urethra of 20 normal, adult male dogs. staphylococcus aureus and streptococcus canis were the most frequently isolated bacteria in specimens collected from the vagina (in the area of the urethral orifice) of 20 normal intact bitches and 20 spayed bitches. a significant difference was not found in the observed frequency of occurrence of any of the microo ... | 1978 | 646206 |
| streptococcus canis: an isolate from a canine uterus. | | 1975 | 1041521 |
| [bacteriology and mycology of otitis externa in dogs]. | the bacterial and fungal flora of 1118 ears of dogs with otitis externa and 100 ears of healthy control dogs were studied in order to isolate the causative agents. the yeast malassezia pachydermatis (56%) was by far the most common organism in otitic dogs followed by the bacteria staphylococcus intermedius (23%), pseudomonas aeruginosa (12%), proteus spp. (6%) and streptococcus canis (5%). a statistical analysis of observed results showed that the incidence of these organisms is significant in o ... | 1992 | 1411421 |
| identification and composition of the tonsillar and anal enterococcal and streptococcal flora of dogs and cats. | enterococcus faecalis was the most frequently isolated enterococcal species from anal swabs and tonsils of dogs and cats, although in the anal samples from dogs ent. hirae was found almost as often as ent. faecalis. most ent. faecium strains from dog tonsils differed from those associated with humans and other animals in that they fermented sorbitol. typical ent. avium as well as atypical ent. avium-like strains were seen in dogs, while the related species ent. raffinosus was associated with cat ... | 1992 | 1447058 |
| streptococcus canis arthritis in a cat breeding colony. | this is the first description of a pathologic condition--arthritis in cats affecting mainly one joint, i.e. monarthritis--caused by streptococcus canis (s. canis), of the lancefield serologic group g. six cases were recorded in a closed cat breeding colony during a 6 month period in 1988, and one additional case in 1990. therapy with penicillin and streptomycin led to full recovery in four of six cases. the bacterium had been detected from different purulent processes sporadically--including one ... | 1991 | 1883871 |
| antibacterial properties of saliva: role in maternal periparturient grooming and in licking wounds. | canine saliva was tested for its bactericidal effects against pathogens relevant to the presumed hygienic functions of maternal grooming of the mammary and anogenital areas and licking of wounds. both female and male saliva were bactericidal against escherichia coli and streptococcus canis but only slightly, and nonsignificantly, bactericidal against coagulase positive staphylococcus and pseudomonas aeruginosa. e. coli is the cause of highly fatal coliform enteritis of neonatal mammals and e. co ... | 1990 | 2125128 |
| bacterial flora of the vagina and uterus of healthy cats. | bacterial culturing was conducted on samples from the reproductive tracts of 53 clinically healthy female cats. aerobic bacteria were isolated from 52 of 53 vaginal swab samples and from 2 of 29 uterine swab samples. anaerobic bacteria were detected in 4 of 30 vaginal and 1 of 29 uterine cultures. the aerobic bacteria included species of acinetobacter, actinomyces, corynebacterium, escherichia, haemophilus, klebsiella, lactobacillus, staphylococcus, and streptococcus. coagulase-negative staphylo ... | 1990 | 2179182 |
| purification and partial characterization of a cohaemolysin (camp-factor) produced by streptococcus canis. | a cohaemolysin from the culture supernate of a canine pathogenic group g streptococcus (s. canis) was purified to electrophoretic homogeneity. the purification procedure involved ammonium sulphate precipitation, ultrafiltration, gel filtration and preparative isoelectric focusing. the cohaemolysin consisted of a single polypeptide chain, 18.6 kda, with an isoelectric point at ph 5.1. the protein reacted with an homologous antiserum, appeared to be trypsin-sensitive and relatively heat-stable. th ... | 1990 | 2257165 |
| multiple forms of ifn-beta 2/il-6 in serum and body fluids during acute bacterial infection. | many of the major alterations in plasma proteins characteristic of the hepatic acute phase response are regulated by ifn-beta 2/il-6. using a specific bioassay for ifn-beta 2/il-6, which relies on the induction of the hepatic acute phase plasma protein alpha 1-antichymotrypsin in the human hepatoma cell line hep3b clone 2 and its inhibition by anti-rifn-beta 2/il-6 antiserum, we have detected high levels of ifn-beta 2/il-6 in the body fluids of patients with acute bacterial infections. cerebrosp ... | 1989 | 2536416 |
| binding activity of streptococcus canis for albumin and other plasma proteins. | all 24 cultures of streptococcus canis examined bound 125i-labelled human albumin, igg and fibrinogen; but neither iga nor haptoglobin. binding of human albumin was time-dependent, saturable and reversible by the addition of unlabelled albumin. the binding of 125i-labelled human albumin could be inhibited completely by unlabelled albumin preparations from humans, mice and dogs, and partly by bovine albumin. in contrast, binding of 125i-labelled human albumin was not inhibited by unlabelled rabbi ... | 1988 | 3253409 |
| the anal region as a main carrier site of staphylococcus intermedius and streptococcus canis in dogs. | | 1987 | 3424574 |
| serogroups and biotypes among beta-hemolytic streptococci of canine origin. | a study of hemolytic streptococci from clinical infections in dogs revealed the presence of four serogroups, with one to four biotypes in each, based on carbohydrate fermentation patterns. of 254 isolates tested, 206 belonged to lancefield group g, 30 to group c, 7 to group e, and 1 to group a. ten isolates could not be grouped. reactions on the three key carbohydrates, lactose, trehalose, and sorbitol, revealed four biotypes each in groups g and c, and two in group e and among the ungroupable c ... | 1980 | 7430328 |
| neonatal sepsis due to group g streptococci. | two cases of neonatal septicaemia due to group g streptococci (streptococcus canis) are described. in one patient, infection coexisted with transient neonatal hyperthyroidism, while, in the other, concomitant group g streptococcal septicaemia and endometritis in the mother was seen. group g streptococci are rare causes of infection, especially in the paediatric age group. bacteria were identified by serological and biochemical methods. both neonates responded well to penicillin therapy, but the ... | 1980 | 7446105 |
| clinical pharmacologic aspects of cefixime in dogs. | the minimal inhibitory concentration (mic) of cefixime, a new third-generation orally administered caphalosporin, was determined for reference and clinical isolates from dogs. the mic of the drug for all but 1 of the 18 enterobacteriaceae isolates tested, 1 pasteurella canis, 1 rhodococcus equi, 1 streptococcus canis, and 1 streptococcus group g isolate, was less than 1.0 microgram/ml. the mic for 9 staphylococcus intermedius isolates ranged from 1.56 to 6.25 micrograms/ml and, for 8 sta aureus ... | 1995 | 7661460 |
| biochemical properties and whole-cell protein profiles of group g streptococci isolated from dogs. | whole-cell protein profiles obtained by sds-page were used in conjunction with physiological tests to differentiate strains of streptococcus canis isolated from dogs. fermentation of trehalose and lactose, aesculin hydrolysis together with production of beta-d-glucuronidase and alpha-d-galactosidase allowed the demonstration of nine different biotypes. however, visual analysis of the protein patterns and comparison by the coefficient of dice showed minor differences in band patterns among strain ... | 1994 | 7989268 |
| uterine, cervical and vaginal microflora of the normal bitch throughout the reproductive cycle. | samples for microbiological culture were collected from the uterus of bitches using transcervical uterine cannulation (31 samples, 23 bitches) and from the uterus, cervix and vagina post mortem (19 bitches) at all stages of the reproductive cycle. samples were cultured for aerobic and anaerobic bacteria and for aerobic mycoplasmas. bacteria were always found in the uterus during pro-oestrus and oestrus (12 positive in 12 cultures) and rarely at other stages of the reproductive cycle: during anoe ... | 1996 | 8656593 |
| streptococcal toxic shock syndrome in dogs. | to determine the clinical, pathologic, and bacteriologic findings in dogs that developed severe invasive infections with group g streptococci (ggs) over a 6-month period in southern ontario. | 1996 | 8870738 |
| septicemia caused by streptococcus canis in a human. | we describe a case of septicemia due to streptococcus canis in a 77-year-old man. the organism was presumably transmitted from a domestic animal. ulcers of the lower limbs were the likely portals of entry. the differentiation between streptococcus canis and streptococcus dysgalactiae was based on biochemical properties and dna macrorestriction analysis by pulsed-field gel electrophoresis. | 1997 | 9041434 |
| wound contamination and antimicrobial susceptibility of bacteria cultured during total ear canal ablation and lateral bulla osteotomy in dogs. | to detect contamination of wound sites from surgical handling of excised tissues during total ear canal ablation and lateral bulla osteotomy in dogs, and to compare susceptibility of bacterial isolates to cefazolin with susceptibility to other antimicrobial agents. | 1999 | 10363095 |
| relatedness of streptococcus canis from canine streptococcal toxic shock syndrome and necrotizing fasciitis. | the emergence of streptococcal toxic shock syndrome (stss) and necrotizing fasciitis (nf) in dogs caused by streptococcus canis has been reported by our laboratory. since clonal expansion is thought to be partially responsible for the spread of invasive strains of streptococcus pyogenes in humans, the relatedness of 15 isolates of s. canis from canine stss and/or nf was examined using pulsed field gel electrophoresis and biotyping; production of proteases and of a camp-like reaction were also ex ... | 1999 | 10369564 |
| virulence of streptococcus canis from canine streptococcal toxic shock syndrome and necrotizing fasciitis. | the recent recognition of streptococcal toxic shock syndrome (stss) and necrotizing fasciitis (nf) in dogs caused by streptococcus canis highlights our lack of knowledge regarding the mechanisms of virulence of this organism. fifteen isolates of s. canis from cases of canine stss and/or nf were examined for the presence of 10 streptococcus pyogenes-associated virulence genes by southern hybridizations using gene probes generated by pcr. the isolates lacked dna with homology to eight of the 10 ge ... | 1999 | 10591501 |
| in vitro activity of difloxacin against canine bacterial isolates. | the in vitro activity of difloxacin against canine bacterial isolates from clinical cases was studied in the united states and the netherlands. minimal inhibitory concentrations (mic), the postantibiotic effect, the effect of ph on antimicrobial activity, and the bacterial killing rate tests were determined according to standard techniques. the mics of american and dutch isolates agreed in general. the mics of the american gram-negative isolates ranged from 0.06 to 2.0 microg/ml, and the mics of ... | 2000 | 10826834 |
| an unusual streptococcus from human urine, streptococcus urinalis sp. nov. | biochemical, molecular chemical and molecular genetic studies were performed on an unknown gram-positive, catalase-negative, chain-forming coccus isolated from the urine of a patient suffering from cystitis. comparative 16s rrna gene sequencing showed that the organism is a member of the 'pyogenic subgroup' of the genus streptococcus and has a close affinity with streptococcus pyogenes and streptococcus canis. the unknown coccus was, however, readily distinguished from these species and other st ... | 2000 | 10843060 |
| pulmonary pathology of harbour porpoises (phocoena phocoena) stranded in england and wales between 1990 and 1996. | the pathological changes observed in the lungs of 197 freshly dead to moderately decomposed harbour porpoises (phocoenaphocoena) stranded in england and wales between october 1990 and december 1996 were reviewed. in 135 (69 per cent of the cases) macroscopic nematode infections of the bronchial tract with pseudalius inflexus and torynurus convolutus, either singly or in combination, were recorded, and 106 (54 per cent) also had p inflexus within the pulmonary blood vessels. all the macroscopical ... | 2000 | 10901214 |
| identification of isolates of streptococcus canis infecting humans. | during a survey of group g and c streptococcal infections of humans two epidemiologically unrelated group g streptococcal isolates were identified, one from a case of bacteremia and one from a wound infection. these isolates were atypical among this sample in that the emm gene could not be amplified from them by pcr. biochemical characterization identified the isolates as streptococcus canis, an organism normally associated with animal hosts. the biochemical identification was confirmed by seque ... | 2001 | 11682560 |
| recurrent septicemia caused by streptococcus canis after a dog bite. | human infection with streptococcus canis is extremely rare. we describe herein a case of septicemia with cellulitis caused by s. canis in a 75-y-old woman, which developed 2 weeks after a dog bite. macrorestriction analysis with pulsed-field gel electrophoresis demonstrated that the organism had been transmitted by means of a dog bite to her hand. | 2001 | 11868767 |
| use of computerized image analysis to quantify staphylococcal adhesion to canine corneocytes: does breed and body site have any relevance to the pathogenesis of pyoderma? | an optimized system of computerized image analysis was used to investigate variations in the adherence of staphylococcus intermedius to canine corneocytes from four different breed groups and six different anatomical sites. s. intermedius showed significantly greater adherence to the head and neck compared with the dorsum, but adherence to the limb, axilla and groin did not differ from other sites. furthermore, there was significantly greater adherence of s. intermedius to corneocytes from the d ... | 2002 | 11896968 |
| streptococcus equisimilis infection in striped skunks (mephitis mephitis) in saskatchewan. | three radio-collared striped skunks (mephitis mephitis) found dead during a field study of winter ecology of striped skunks near willowbrook, saskatchewan, canada were examined. streptococcus equisimilis was identified as the primary agent causing necrotizing purulent pneumonia in one skunk and suppurative meningoencephalitis in another. both streptococcus equisimilis and streptococcus canis were isolated from lesions of purulent myocarditis and pyothorax in the third skunk. these are apparently ... | 2002 | 12238389 |
| development of pcr assays for detection of streptococcus canis. | streptococcus canis isolates, also including s. canis of artificially contaminated milk, could be identified by polymerase chain reaction (pcr) amplification using oligonucleotide primers designed according to species-specific parts of the 16s rrna gene and, after sequencing, according to s. canis-specific parts of the 16s-23s rdna intergenic spacer region and with oligonucleotide primers detecting an internal fragment of the group g streptococcal camp factor gene cfg. the 16s rrna gene- and cam ... | 2003 | 12620622 |
| septic fibrinous pericarditis in a cocker spaniel. | a four-year-old cocker spaniel presented with cardiac tamponade due to a pericardial effusion, in addition to pyrexia and peripheral neutrophilia and a recent history of chest trauma. cytological examination of the pericardial effusion revealed a predominant neutrophilia. the echocardiographic findings were of numerous hyperechoic densities in the pericardial space, due to fibrin, with concurrent thickening and distortion of the pericardium. postmortem examination, including microbiology, reveal ... | 2003 | 12653326 |
| a fluoroquinolone induces a novel mitogen-encoding bacteriophage in streptococcus canis. | this study investigated whether the recently recognized emergence of canine streptococcal toxic shock syndrome (stss) and necrotizing fasciitis (nf) might be partly attributed to the use of fluoroquinolones to treat streptococcus canis infections in dogs. both mitomycin and the fluoroquinolone enrofloxacin caused bacteriophage-induced lysis of s. canis strain 34, an isolate from a case of canine stss and nf. fluoroquinolone-evoked, bacteriophage-induced lysis occurred over a range of concentrati ... | 2003 | 12761079 |
| isolation of streptococcus canis from a japanese raccoon dog with fibrinous pleuropneumonia. | | 2003 | 14584580 |
| identification of superantigen genes spem, ssa, and smez in invasive strains of beta-hemolytic group c and g streptococci recovered from humans. | group c and g streptococcus dysgalactiae subspecies equisimilis (gcse and ggse) cause a substantial percentage of invasive disease caused by beta-hemolytic streptococci. to determine whether streptococcus pyogenes superantigen (sag) genes commonly exist within these organisms, 20 recent invasive gcse and ggse human isolates and one group g streptococcus canis human isolate were tested for the presence of sag genes speh, spej, spel, spem, ssa and smez by polymerase chain reaction (pcr). prior to ... | 2003 | 14680708 |
| identification of streptococcus canis isolated from milk of dairy cows with subclinical mastitis. | streptococcus canis was isolated from 31 milk samples from 11 cows in a dairy herd (with 49 lactating cows) affected by subclinical mastitis in north rhine-westphalia, germany. thirty-one isolates from the infected udder quarters were further characterized for their phenotypic and molecular properties. most isolates (83.9%) produced alpha-galactosidase, and all were negative for beta-d-glucuronidase. amplification of the 16s rrna gene by the pcr method and digestion with the restriction enzymes ... | 2005 | 15750089 |
| cross-infection between cats and cows: origin and control of streptococcus canis mastitis in a dairy herd. | group g streptococci in animals usually belong to the species streptococcus canis and are most commonly found in dogs and cats. occasionally, strep. canis is detected in milk from dairy cows. an outbreak of strep. canis mastitis in a dairy herd is described. based on results from bacterial culture and ribotyping, a cat with chronic sinusitis was the most likely source of the outbreak. subsequent cow-to-cow transmission of strep. canis was facilitated by poor udder health management, including us ... | 2005 | 16027183 |
| an outbreak of streptococcus canis mastitis in a dairy herd in israel. | an increase in the bulk somatic cell count (bscc) of up to 1,000 x 103 cells/ml occurred in a dairy herd in israel at the end of 2001 and beginning of 2002. | 2005 | 16044188 |
| acquired antimicrobial resistance in the intestinal microbiota of diverse cat populations. | the aim of this study was to investigate the prevalence of acquired antimicrobial resistance in the resident intestinal microbiota of cats and to identify significant differences between various cat populations. escherichia coli, enterococcus faecalis, e. faecium and streptococcus canis were isolated as faecal indicator bacteria from rectal swabs of 47 individually owned cats, 47 cattery cats and 18 hospitalised cats, and submitted through antimicrobial sensitivity tests. the results revealed th ... | 2006 | 16330058 |
| evaluation of the relationship between causative organisms and clinical characteristics of infective endocarditis in dogs: 71 cases (1992-2005). | to evaluate microbiologic findings in dogs with infective endocarditis (ie) and determine whether there were differences in clinical features of disease caused by different groups of infective agents. | 2006 | 16740074 |
| fatal streptococcus canis infections in intensively housed shelter cats. | three independent, fatal outbreaks of streptococcus canis infection occurred in a 2-year period in shelter cats. the outbreaks occurred in northern california (yolo county), southern california (kern county), and north carolina (guilford county). an estimation of the affected population is >150 cats among 3 affected shelters, with a mortality rate of up to 30%. among 20 cats submitted for necropsy there were 2 distinct pathologic presentations. the first (shelters 1 and 2) was skin ulceration an ... | 2007 | 17317801 |
| streptococcus canis infections in humans: retrospective study of 54 patients. | this 5-year retrospective study reports 54 patients with infection, caused by streptococcus canis, a pyogenic lancefield group g streptococcus initially isolated from various animal sources. during 1997-2002, streptococcus canis accounted for 1% of all streptococci isolated. the clinical signs, outcome and bacteriological characteristics were reviewed. all except eight were symptomatic. clinical manifestations were: soft tissue infection (n=35), bacteremia (n=5), urinary infection (n=3), bone in ... | 2007 | 17320186 |
| the other group g streptococcus: increased detection of streptococcus canis ulcer infections in dog owners. | beta-hemolytic lancefield group g streptococcus dysgalactiae and streptococcus canis cannot be distinguished when only lancefield typing is performed. phenotypic testing and 16s rrna gene sequencing identified s. canis associated with ulcer infections in dog owners. because s. canis may be incorrectly identified (published biochemical descriptions are inconsistent), there may be an underestimation of the true number of infections. identification of group g streptococci to the species level could ... | 2007 | 17475761 |
| streptococcus ictaluri sp. nov., isolated from channel catfish ictalurus punctatus broodstock. | a streptococcal-like organism was associated with diseased channel catfish ictalurus punctatus broodstock on four commercial aquaculture operations in the mississippi delta. conventional biochemical testing, 16s rrna gene sequence analysis and dna-dna hybridization distinguished the isolates from these fish from previously published streptococcus species. comparative 16s rrna gene sequencing studies revealed that the isolates were phylogenetically most similar to streptococcus iniae, streptococc ... | 2007 | 17625202 |
| occurrence of antimicrobial resistance in bacteria from diagnostic samples from dogs. | to study the occurrence of antimicrobial resistance among common bacterial pathogens from dogs and relate resistance patterns to data on consumption of antimicrobials. | 2007 | 17644533 |
| identification and antimicrobial susceptibility of bacteria and yeasts isolated from healthy dogs and dogs with otitis externa. | the bacterial and fungal flora of the external ear canal of dogs with otitis externa and of healthy dogs were studied. the most frequently isolated microorganism from otitic ears was staphylococcus intermedius (58.8%), followed by malassezia pachydermatis (30.9%), streptococcus canis (29.9%), proteus spp. (14.4%) and escherichia coli (10.3%). a statistical analysis of our results showed that the prevalence of these microorganisms is significant in dogs with otitis externa. furthermore, the antim ... | 2007 | 18045339 |
| mitral stenosis with bacterial myocarditis in a cat. | an eleven-year-old female japanese mongrel cat was referred to the tottori university veterinary teaching hospital for assessment of acute paresis and dyspnea. two-dimensional echocardiography showed a hydropericardium. the mitral valve leaflets were thickened, the separation of the right and left leaflets was not complete. treatments with intravenous fluids of lactate ringer solution, furosemide, urokinase, antibiotics were initiated, but did not improve the respiratory failure. the cat died 10 ... | 2007 | 18057833 |
| fatal necrotising fasciitis and myositis in a cat associated with streptococcus canis. | necrotising fasciitis and necrotising myositis are rare but serious life threatening conditions reported mainly in human beings and dogs. most cases to date have been caused by beta-haemolytic streptococci of lancefield groups a, b, c or g. necrotising fasciitis has been reported only twice in cats and necrotising myositis has never been described. this paper describes a fatal case of necrotising fasciitis and myositis with pneumonia and septicaemia in a nine-year-old cat. the cat had been under ... | 2008 | 18390855 |
| molecular diagnosis of prosthetic valve endocarditis with aorto-right atrial fistula. | definite diagnosis of infective endocarditis is impossible when all blood cultures are negative under antibiotic treatment. in this case, streptococcus canis was identified using polymerase chain reaction from preoperative whole blood and excised valve tissue, and considered as the pathogen for infective endocarditis, despite negative blood cultures. this information was useful for diagnosis and selection of antibiotics. | 2009 | 18582966 |
| necrotising fasciitis with sub-periosteal streptococcus canis infection in two puppies. | necrotising fasciitis is an uncommon and potentially devastating disease which has been infrequently reported in animals. this brief communication describes an unusual presentation of necrotising fasciitis in two immature bull terriers. both animals were admitted with a history of minimal trauma yet rapidly progressive, localising, disproportionate pain. streptococcus canis was cultured from sub-periosteal fluid-filled pockets surrounding the femur in both cases. | 2008 | 19011715 |
| genetic relationships deduced from emm and multilocus sequence typing of invasive streptococcus dysgalactiae subsp. equisimilis and s. canis recovered from isolates collected in the united states. | beta-hemolytic group c and g streptococci cause a considerable invasive disease burden and sometimes cause disease outbreaks. little is known about the critical epidemiologic parameter of genetic relatedness between isolates. we determined the emm types of 334 streptococcus dysgalactiae subsp. equisimilis isolates, and attempted emm typing of 5 streptococcus canis isolates from a recent population-based surveillance for invasive isolates. thirty-four emm types were observed, including one from s ... | 2009 | 19386831 |
| pathogen detection in milk samples by ligation detection reaction-mediated universal array method. | this paper describes a new dna chip, based on the use of a ligation detection reaction coupled to a universal array, developed to detect and analyze, directly from milk samples, microbial pathogens known to cause bovine, ovine, and caprine mastitis or to be responsible for foodborne intoxication or infection, or both. probes were designed for the identification of 15 different bacterial groups: staphylococcus aureus, streptococcus agalactiae, nonaureus staphylococci, streptococcus bovis, strepto ... | 2009 | 19528580 |
| staphylococcus pseudintermedius necrotizing fasciitis in a dog. | staphylococcus pseudintermedius was implicated as the cause of rapidly progressive and fatal necrotizing fasciitis in a dog. the isolate was methicillin-susceptible and did not contain genes encoding the panton-valentine leukocidin. while streptococcus canis is typically considered to be the main cause of necrotizing fasciitis in dogs, staphylococci should also be considered. | 2009 | 19721787 |
| in vitro antimicrobial activity of a commercial ear antiseptic containing chlorhexidine and tris-edta. | minimum bactericidal concentrations (mbcs) of a commercial ear antiseptic containing chlorhexidine 0.15% and tris-edta (otodine) were determined by broth microdilution for 150 isolates representing the most common pathogens associated with canine otitis. the microorganisms were classified into three groups according to their levels of susceptibility. the most susceptible group included staphylococcus pseudintermedius, malassezia pachydermatis, streptococcus canis and corynebacterium auriscanis, ... | 2010 | 20030799 |
| characterization of a new protective antigen of streptococcus canis. | streptococcus canis (s. canis), a lancefield group g streptococcus, is an opportunistic pathogen mainly found in dogs and cats. the study on pathogenesis and protective immune mechanism of s. canis is not clear. a new streptococcal protective antigen (spa) was first identified from a genomic library of s. canis. spa of s. canis (spasc) contained a 1224-bp open reading frame which encoded a 407aa protein and a 34-aa signal sequence with a deduced molecular mass of 46.368 kda. protein analysis and ... | 2010 | 20490660 |
| relationship between clinical manifestations and pulsed-field gel profiles of streptococcus canis isolates from dogs and cats. | little is known regarding the degree of genotypic relatedness between streptococcus canis isolates from dogs and cats. the purpose of this study was to determine whether correlations existed between the genotypes of canine and feline s. canis isolates as determined using pulsed-field gel electrophoresis (pfge) and different clinical manifestations of disease. eighty-two isolates of s. canis were examined that had been collected from dogs and cats presenting to the university of california, davis ... | 2010 | 20605376 |
| aerobic bacteria from mucous membranes, ear canals, and skin wounds of feral cats in grenada, and the antimicrobial drug susceptibility of major isolates. | in a 2-year period 54 feral cats were captured in grenada, west indies, and a total of 383 samples consisting of swabs from rectum, vagina, ears, eyes, mouth, nose and wounds/abscesses, were cultured for aerobic bacteria and campylobacters. a total of 251 bacterial isolates were obtained, of which 205 were identified to species level and 46 to genus level. a commercial bacterial identification system (api/biomerieux), was used for this purpose. the most common species was escherichia coli (n=60) ... | 2011 | 20627391 |
| scm, a novel m-like protein from streptococcus canis, binds (mini)-plasminogen with high affinity and facilitates bacterial transmigration. | streptococcus canis is an important zoonotic pathogen capable of causing serious invasive diseases in domestic animals and humans. in the present paper we report the binding of human plasminogen to s. canis and the recruitment of proteolytically active plasmin on its surface. the binding receptor for plasminogen was identified as a novel m-like protein designated scm (s. canis m-like protein). spr (surface plasmon resonance) analyses, radioactive dot-blot analyses and heterologous expression on ... | 2011 | 21210764 |
| pyogenic streptococci--danger of re-emerging pathogens. | beta-hemolytic, pyogenic streptococci are classified according to type of major surface antigen into a (streptococcus pyogenes), b (streptococcus agalactiae), c (multiple species including streptococcus dysagalactiae) and g (multiple species including streptococcus canis) lancefield groups. group a streptococcus causes each year hundreds of thousands deaths globally as a result of infections and post-infectional sequelae. an increasing number of severe, invasive infections is caused by selected, ... | 2010 | 21466038 |
| Bactericidal properties of pradofloxacin against veterinary pathogens. | Pradofloxacin is a new veterinary 8-cyano-fluoroquinolone developed for use against bacterial infections in dogs and cats involving both aerobic and anaerobic bacteria. The minimal bactericidal concentrations have been determined against clinical isolates of Staphylococcus pseudintermedius, Staphylococcus aureus, Escherichia coli, Pasteurella multocida, Streptococcus canis, Proteus spp., Fusobacterium spp., Porphyromonas gingivalis and Prevotella species. A subset of these species was selected, ... | 2011 | 22209121 |
| photodynamic therapy against common bacteria causing wound and skin infections. | photodynamic therapy (pdt) uses the combination of a photosensitising (ps) agent and visible light. historically, various injectable ps agents have been used with medical grade lasers to treat neoplasia. the objective of this in vitro study was to determine whether pdt using topical aminolevulinic acid (ala) with a non-coherent light source would kill common wound infecting bacteria, namely, staphylococcus intermedius, streptococcus canis, pseudomonas aeruginosa, and escherichia coli. bacterial ... | 2011 | 22000592 |
| Delineation of Streptococcus dysgalactiae, Its Subspecies, and Its Clinical and Phylogenetic Relationship to Streptococcus pyogenes. | The taxonomic status and structure of Streptococcus dysgalactiae have been the object of much confusion. Bacteria belonging to this species are usually referred to as Lancefield group C or group G streptococci in clinical settings in spite of the fact that these terms lack precision and prevent recognition of the exact clinical relevance of these bacteria. The purpose of this study was to develop an improved basis for delineation and identification of the individual species of the pyogenic group ... | 2012 | 22075580 |
| zoonotic streptococcus canis infection in singapore. | | 2016 | 27076048 |
| genome characterization and population genetic structure of the zoonotic pathogen, streptococcus canis. | streptococcus canis is an important opportunistic pathogen of dogs and cats that can also infect a wide range of additional mammals including cows where it can cause mastitis. it is also an emerging human pathogen. | 2012 | 23244770 |
| staphylococcus spp., streptococcus canis, and arcanobacterium phocae of healthy canadian farmed mink and mink with pododermatitis. | pododermatitis is a disease of concern for mink breeders in canada and worldwide, as it causes discomfort and lowers the breeding rates on farms affected by the disease. unfortunately, the etiology and pathogenesis of pododermatitis are still unknown. in this study, we compared staphylococcus spp. and streptococcus canis isolates from healthy mink with isolates from animals with pododermatitis on 2 farms in ontario. almost all hemolytic staphylococcus spp. isolated were shown to be staphylococcu ... | 2015 | 25852228 |
| pediatric feline upper respiratory disease. | infectious feline upper respiratory tract disease (urtd) continues to be a widespread and important cause of morbidity and mortality in kittens. multiple pathogens can contribute to urtd in kittens, and coinfections are common in overcrowded environments and contribute to increased disease severity. worldwide, the most prevalent pathogens are feline herpesvirus-1 and feline calicivirus. primary bacterial causes of urtd in cats include bordetella bronchiseptica, chlamydia felis, and mycoplasma sp ... | 2014 | 24580994 |
| antimicrobial susceptibility monitoring of bacterial pathogens isolated from urinary tract infections in dogs and cats across europe: compath results. | compath is a pan-european antimicrobial surveillance program collecting bacterial pathogens from dogs and cats not recently exposed to antimicrobials. we present minimum inhibitory concentration data obtained using clinical and laboratory standards institute methodology for 616 urinary tract infection (uti) isolates collected between 2008 and 2010. in both dogs and cats, the most common pathogen was escherichia coli (59.8% and 46.7%, respectively). antimicrobial activity against e. coli in dogs ... | 2017 | 28384093 |
| antimicrobial resistance in bacteria from breeding dogs housed in kennels with differing neonatal mortality and use of antibiotics. | this work examines the antimicrobial resistance of potentially pathogenic bacteria (staphylococcus pseudintermedius, streptococcus canis, escherichia coli) found in the vaginal tract in prepartum mammary secretions and postpartum milk of bitches housed in breeding kennels (n = 20; 92 bitches). the kennels were divided into three categories: no routine antimicrobial administration around parturition (category 1); routine administration of one antibiotic around parturition (category 2); routine ad ... | 2012 | 22898018 |
| the in vitro activity of 15 antimicrobial agents against bacterial isolates from dogs. | the in vitro activity of 15 antimicrobial agents against clinical isolates of staphylococcus pseudintermedius, staphylococcus aureus, escherichia coli, pasteurella spp. and streptococcus canis from dogs was investigated. for staphylococcus spp., the highest frequency of resistance was observed for penicillin, followed by ampicillin, tetracycline and chloramphenicol. the highest frequency of resistance in e. coli isolates was recorded for tetracycline and streptomycin. pasteurella spp. and s. can ... | 2012 | 22516694 |
| persistent corneal epithelial defect responding to rebamipide ophthalmic solution in a patient with diabetes. | rebamipide ophthalmic suspension was developed for the treatment of dry eyes and for other corneal diseases, promoting the secretion of both mucin in tear fluid and membrane-associated mucin, increasing the number of goblet cells, and restoring the barrier function of the corneal epithelium. we report a case of a persistent corneal epithelial defect in a patient with diabetes treated with topical application of rebamipide ophthalmic suspension. | 2016 | 27257394 |
| chromosomal islands of streptococcus pyogenes and related streptococci: molecular switches for survival and virulence. | streptococcus pyogenes is a significant pathogen of humans, annually causing over 700,000,000 infections and 500,000 deaths. virulence in s. pyogenes is closely linked to mobile genetic elements like phages and chromosomal islands (ci). s. pyogenes phage-like chromosomal islands (spyci) confer a complex mutator phenotype on their host. spyci integrate into the 5' end of dna mismatch repair (mmr) gene mutl, which also disrupts downstream operon genes lmrp, ruva, and tag. during early logarithmic ... | 2014 | 25161960 |
| biofilm-infected wounds in a dog. | a 4-year-old spayed female mastiff was evaluated for treatment of chronic nonhealing pressure wounds over both elbow regions resulting from attempts at hypertrophic callus excision. | 2014 | 24568112 |
| short communication: streptococcus canis is able to establish a persistent udder infection in a dairy herd. | bovine mastitis caused by streptococcus canis is relatively rare. consequently, many epidemiologic aspects of the infection, including factors that mediate crossing of host species barriers by the pathogen, infectiousness of the microorganism to the mammary gland, and the course of the disease within a herd, are still not elucidated. therefore, the aim of the present study was to describe results of a 15-mo observation of subclinical strep. canis mastitis on a dairy farm housing 76 lactating hol ... | 2015 | 26233445 |
| gene repertoire evolution of streptococcus pyogenes inferred from phylogenomic analysis with streptococcus canis and streptococcus dysgalactiae. | streptococcus pyogenes, is an important human pathogen classified within the pyogenic group of streptococci, exclusively adapted to the human host. our goal was to employ a comparative evolutionary approach to better understand the genomic events concomitant with s. pyogenes human adaptation. as part of ascertaining these events, we sequenced the genome of one of the potential sister species, the agricultural pathogen s. canis, and combined it in a comparative genomics reconciliation analysis wi ... | 2012 | 22666370 |
| human case of bacteremia caused by streptococcus canis sequence type 9 harboring the scm gene. | streptococcus canis (sc) is a zoonotic pathogen that is transferred mainly from companion animals to humans. one of the major virulence factors in sc is the m-like protein encoded by the scm gene, which is involved in anti-phagocytic activities, as well as the recruitment of plasminogen to the bacterial surface in cooperation with enolase, and the consequent enhancement of bacterial transmigration and survival. this is the first reported human case of uncomplicated bacteremia following a dog bit ... | 2017 | 28180088 |
| multiplex pcr-based identification of streptococcus canis, streptococcus zooepidemicus and streptococcus dysgalactiae subspecies from dogs. | streptococcus canis (s. canis), streptococcus equi subspecies zooepidemicus (s. zooepidemicus) and streptococcus dysgalactiae subspecies (s. dysgalactiae subspecies) are β-haemolytic gram positive bacteria infecting animals and humans. s. canis and s. zooepidemicus are considered as two of the major zoonotic species of streptococcus, while more research is needed on s. dysgalactiae subspecies bacteria. in this work, a multiplex-pcr protocol was tested on strains and clinical samples to detect s. ... | 2017 | 28131378 |
| biotypes and scm types of isolates of streptococcus canis from diseased and healthy cats. | lancefield group g streptococcus canis is a component of the normal urogenital and pharyngeal flora of the cat. it is also frequently implicated in epizootics of severe disease in closed cat colonies and animal shelters. given the importance of s canis as a feline pathogen and relative lack of published information on characteristics potentially associated with virulence, the authors have compared isolates from healthy and diseased cats in new york and california using fermentation profiles (bio ... | 2017 | 28077757 |
| identification of group g streptococci isolates from companion animals in japan and their antimicrobial resistance. | this study determined species-level identification and antimicrobial resistance (amr) properties in group g streptococci (ggs) isolates from companion animals in japan. strains were isolated from sterile/non-sterile specimens of 72 animals with clinical symptoms or signs in april-may, 2015. we identified them based on 16s rrna sequencing, mass spectrometry (ms), and an automated method based on their biochemical properties. antimicrobial susceptibility was determined with broth microdilution met ... | 2016 | 28003600 |
| scm-positive streptococcus canis are predominant among pet-associated group g streptococci. | streptococcus (s.) canis is a neglected zoonotic pathogen with increasing impor- tance. since knowledge about its distribution in pets in germany is scant, we designed a study and tested 335 dogs and 71 cats for colonization by s. canis. s. canis was isolated from swabs taken from the perianal region by culture and subsequent identification was performed biochemically as well as by pcr. in total, 15.8% (53) of the canine and 8.5% (six) of the feline strains grown on staphlyo- coccus/streptococcu ... | 2016 | 27344918 |
| sharing a microbe with man's best friend: a case of canine streptococcal infection in a diabetic patient. | we report a case of a diabetic patient with an infected leg wound leading to septicemia and abscess formation in the contra-lateral leg due to streptococcus canis. this organism belongs to the lancefield group g and is more commonly found in dogs. it is often mistaken for streptococcus dysgalactiae which is a human strain of streptococci. infections in humans are not common and usually involve infected wounds or ulcers and the surrounding soft tissue. in most reported cases, patients had close c ... | 2015 | 26556125 |
| endocarditis caused by streptococcus canis: an emerging zoonosis? | we report a human case of infective endocarditis caused by streptococcus canis. identification was carried out from positive blood culture using mass spectrometry and soda gene sequencing. s. canis related zoonotic invasive infections may have been previously underdiagnosed due to inadequate identification of group g streptococcus species. | 2016 | 26104727 |
| streptococcal infections in cats: abcd guidelines on prevention and management. | streptococcus canis is most prevalent in cats, but recently s equi subsp zooepidemicus has been recognised as an emerging feline pathogen. | 2015 | 26101315 |
| genetic determinants of antimicrobial resistance in streptococcus canis in france. | | 2015 | 27873664 |
| matrix-assisted laser desorption/ionization-time of flight mass spectrometry identification of large colony beta-hemolytic streptococci containing lancefield groups a, c, and g. | the aim of this study was to investigate whether large colony beta-hemolytic streptococci containing lancefield groups a, c, and g can be adequately identified using matrix-assisted laser desorption/ionization-time of flight mass spectrometry (maldi-tof). previous studies show varying results, with an identification rate from below 50% to 100%. | 2015 | 25960250 |
| highly pathogenic beta-hemolytic streptococcal infections in cats from an institutionalized hoarding facility and a multi-species comparison. | two hundred and thirty-four cats removed from an institutionalized hoarding facility (ihf) demonstrated severe, atypical pyogenic infections. the objective of this study was to document the various syndromes and determine the etiology of the infections. | 2016 | 25944581 |
| first reported human case of native mitral infective endocarditis caused by streptococcus canis. | a 65 year-old woman was admitted for acute heart failure and severe sepsis revealing definite mitral infective endocarditis with severe regurgitation, complicated by multiple embolisms. three blood cultures yielded a group g streptococcus canis strain. urgent surgery was performed with bioprosthetic valve replacement. polymerase chain reaction analysis of the valve found s canis dna. amoxicillin and gentamicin were given for 2 weeks followed by 4 weeks of amoxicillin alone. she reported contact ... | 2014 | 25442453 |
| necrotising fasciitis in a domestic shorthair cat--negative pressure wound therapy assisted debridement and reconstruction. | a 10-year-old, domestic shorthair cat was presented for acute lameness of the left forelimb accompanied by severe pain, swelling, skin necrosis, malodorous discharge and pyrexia. following a presumptive diagnosis of necrotising fasciitis aggressive surgical debridement of the affected soft tissues of the antebrachium and negative pressure wound treatment of the open defect were performed. surgical findings supported the tentative diagnosis of necrotising fasciitis and streptococcus canis was iso ... | 2015 | 25323110 |
| contrast-enhanced multidetector computed tomography to diagnose pulmonary thromboembolism in an awake dog with pyothorax. | to (1) describe the use of contrast-enhanced multidetector computed tomography (ce-mdct) for identifying pulmonary thromboembolism (pte) in an awake dog with pyothorax, (2) report the first documented case of pte associated with pyothorax in veterinary medicine, and (3) review diagnostic imaging modalities and therapeutic options for pte. | 2016 | 25297073 |
| what is your diagnosis? blood smear from a cat. | | 2014 | 24931569 |
| bacterial diskospondylitis in juvenile mink from 2 ontario mink farms. | nine juvenile mink with hind-limb paresis/paralysis from 2 ontario farms were submitted for necropsy. diagnostic tests revealed spinal compression and severe thoracic diskospondylitis with intralesional gram-positive coccoid bacterial colonies. streptococcus canis, streptococcus dysgalactiae subsp. equisimilis, and hemolytic staphylococcus spp. were isolated from vertebral lesions. | 2013 | 24155490 |
| cholesterol granuloma associated with otitis media and leptomeningitis in a cat due to a streptococcus canis infection. | cholesterol granuloma in the middle ear is a pathological condition often associated with otitis media in humans. cholesterol granulomas in cats are rarely described. to our knowledge, this is the first report of middle ear cholesterol granuloma in a cat, associated with otitis media and leptomeningitis due to a streptococcus canis septicemia. | 2013 | 23814305 |
| a case of sepsis caused by streptococcus canis in a dog owner: a first case report of sepsis without dog bite in japan. | a 91-year-old dog-owning woman with a history of hypertension and femoral neck fracture consulted our hospital with fever and femur pain with redness. laboratory test results showed leukocytosis with 85% neutrophils and high values of c-reactive protein and procalcitonin. in addition, growth of gram-positive streptococcus was observed in two independent blood culture sets. the isolated bacterium was identified as streptococcus canis on the basis of biochemical properties and sequencing analyses ... | 2013 | 23740090 |
| cooperative plasminogen recruitment to the surface of streptococcus canis via m protein and enolase enhances bacterial survival. | streptococcus canis is a zoonotic pathogen capable of causing serious invasive diseases in domestic animals and humans. surface-exposed m proteins and metabolic enzymes have been characterized as major virulence determinants in various streptococcal species. recently, we have identified scm, the m-like protein of s. canis, as the major receptor for miniplasminogen localized on the bacterial surface. the present study now characterizes the glycolytic enzyme enolase as an additional surface-expose ... | 2013 | 23481605 |
| multilocus sequence analysis of streptococcus canis confirms the zoonotic origin of human infections and reveals genetic exchange with streptococcus dysgalactiae subsp. equisimilis. | streptococcus canis is an animal pathogen that occasionally causes human infections. isolates recovered from infections of animals (n = 78, recovered from 2000 to 2010 in three european countries, mainly from house pets) and humans (n = 7, recovered from 2006 to 2010 in portugal) were identified by phenotypic and genotypic methods and characterized by antimicrobial susceptibility testing, multilocus sequence typing (mlst), pulsed-field gel electrophoresis (pfge), and emm typing. s. canis isolate ... | 2013 | 23345291 |
| epidemiology and pathogenicity of zoonotic streptococci. | zoonotic infections caused by streptococcus spp. have been neglected in spite of the fact that frequency and severity of outbreaks increased dramatically in recent years. this may be due to non-identification since respective species are often not considered in human medical diagnostic procedures. on the other hand, an expanding human population concomitant with an increasing demand for food and the increased number of companion animals favour conditions for host species adaptation of animal str ... | 2013 | 23192319 |
| identification and characterization of the arginine deiminase system of streptococcus canis. | although streptococcus (s.) canis is known to cause severe infections in dogs and cats and harbors a clear zoonotic potential, knowledge about physiology and pathogenesis is mostly elusive. the arginine deiminase system (ads) has been described in certain streptococcal species and its role in the establishment of infection has been suggested. in this study we focused on the identification and characterization of the ads in s. canis. using genome sequencing and subsequent in silico analysis we id ... | 2013 | 22939986 |
| simultaneous streptococcus canis and pasteurella multocida peritonitis in a peritoneal dialysis patient. | | 2017 | 28676516 |
| antimicrobial treatment of necrotizing fasciitis and septic polyarthritis in a cat associated with streptococcus canis infection. | | 2017 | 28776781 |
| scm, the m protein of streptococcus canis binds immunoglobulin g. | the m protein of streptococcus canis (scm) is a virulence factor and serves as a surface-associated receptor with a particular affinity for mini-plasminogen, a cleavage product of the broad-spectrum serine protease plasmin. here, we report that scm has an additional high-affinity immunoglobulin g (igg) binding activity. the ability of a particular s. canis isolate to bind to igg significantly correlates with a scm-positive phenotype, suggesting a dominant role of scm as an igg receptor. subseque ... | 2017 | 28401063 |