| teichoic acids of group d streptococci with special reference to strains from pig meningitis (streptococcus suis). | immunoelectrophoresis revealed in phenol extracts from s. faecalis and s. faecium a mixture of free and lipid-bound teichoic acids, both reactive with group d antisera. in phenol extracts from s. suis only lipid-bound teichoic acid, also reactive with group d antiserum, was seen. this difference probably accounts for the low yield of group d antigen from s. suis as compared with s. faecalis and s. faecium when heating at ph 2 is used for extraction. when phenol is used good yields are obtained f ... | 1977 | 45589 |
| meningitis and endophthalmitis caused by streptococcus suis type ii (group r). | | 1977 | 301419 |
| streptococcus suis type ii (group r) as a cause of endophthalmitis. | a case is reported of a patient with bilateral endophthalmitis, meningitis, sensorineural deafness, labyrinthitis, and septicaemia due to streptococcus suis type ii (group r). the organism is known to produce epidemic meningitis, septicaemia, and purulent arthritis in piglets, but human infection is rare, and no other case reports of ocular infection are known. the organism was sensitive to penicillin at a minimum inhibitory concentration of 0.03 mg/1. | 1978 | 309340 |
| the type-specific polysaccharides of streptococcus suis. | streptococcus suis types 1 and 2 were subjected to digestion with lysozyme. serologically type-specific capsular polysaccharides were isolated from the lysates by ethanol precipitation followed by sepharose 6b chromatography. the purified type 1 polysaccharide has a kd value of 0.074 on a sepharose 4b column and contains galactose, glucose, n-acetyl glucosamine, n-acetyl galactosamine, and sialic acid in a molar ratio of 2.42:1.00:1.00:1.13:1.39. the type 2 polysaccharide has a kd value of 0.185 ... | 1978 | 363973 |
| meningitis in pigs caused by streptococcus suis type ii. | | 1977 | 595268 |
| streptococcus suis type 2 infection in pigs. | | 1978 | 644801 |
| streptococcal infection in young pigs. iv. an outbreak of streptococcal meningitis in weaned pigs. | twenty-eight pigs died in an outbreak of streptococcal meningitis in an east anglian herd. most were 10-14 weeks old. the outbreak lasted from january to april and was finally controlled by antibiotic therapy. a similar number of losses had occurred in the previous year though no diagnosis had then been made. the causal agent appeared to be a haemolytic streptococcus belonging to group d and provisionally designated streptococcus suis type 2. it is probably identical with de moor's group r strep ... | 1975 | 807620 |
| conjugation of antibiotic resistance in streptococcus suis. | forty-eight clinical isolates of streptococcus suis were examined for antibiotic sensitivity and the presence of plasmid dna. it was determined that isolates from this study showed a substantial increase in resistance to erythromycin (ery), clindamycin, and tetracycline (tet) compared to a similar study conducted five years earlier. eleven of the 48 isolates contained plasmid dna as revealed by dna isolation and gel electrophoresis. plasmid dna from four strains resistant to the above three anti ... | 1992 | 1313622 |
| inoculation of pigs with streptococcus suis type 2 alone or in combination with pseudorabies virus. | pigs (9 [+/- 1] weeks old) were inoculated with streptococcus suis type 2, pseudorabies virus (prv), or both. for each pig of groups a, b, and c the inoculum of s suis was 10(9) colony-forming units. for each pig of groups a, b, and d the inoculum of prv was 5 x 10(3) tcid50 of either prv strain 4892 (group a, n = 9) or prv isolate b (group b, n = 9). the prv strain 4892 is a highly virulent strain; isolate b causes mild clinical signs of infection in inoculated pigs. group-c pigs (n = 9) were g ... | 1992 | 1317689 |
| molecular analysis of isolates of streptococcus suis capsular type 2 by restriction-endonuclease-digested dna separated on sds-page and by hybridization with an rdna probe. | this study was undertaken to assess the discriminatory value of restriction endonuclease (re) digestion patterns of streptococcus suis chromosomal dna using polyacrylamide gel electrophoresis (sds-page) and dna-rdna hybridization. for the re digestion patterns, dnas were digested separately with the enzymes bamhi and bglii and the resultant fragments were separated by sds-page. an escherichia coli rdna probe derived from pkk3535 was used for the hybridization. twenty-three s. suis capsular type ... | 1992 | 1362584 |
| identification of n-acetylneuraminyl alpha 2-->3 poly-n-acetyllactosamine glycans as the receptors of sialic acid-binding streptococcus suis strains. | streptococcus suis is a common cause of sepsis, meningitis, and other serious infections in young piglets and also causes meningitis in humans. the cell-binding specificity of sialic acid-recognizing strains of streptococcus suis was investigated. treatment of human erythrocytes with sialidase or mild periodate abolished hemagglutination. hemagglutination inhibition experiments with sialyl oligosaccharides indicated that the adhesin preferred the sequence neunac alpha 2-3gal beta 1-4glc(nac). re ... | 1992 | 1400420 |
| [ocular manifestations of selected zoonoses in humans]. | a report is given on the epidemiology and clinical signs of some selected zoonoses that may be of significance for ocular infections in man: brucellosis, leptospirosis, lyme borreliosis, lymphocytic choriomeningitis, newcastle disease, ornithosis (chlamydiosis), rabies, streptococcus suis infection, larva migrans ocularis by toxocara canis or baylisascaris procyonis, toxoplasmosis and tularemia. | 1992 | 1412422 |
| streptococcus suis meningitis. a severe noncompensated occupational disease. | meningitis caused by streptococcus suis type 2, a rare disease first recognized in 1968 (108 cases worldwide in 1989), is contracted by occupational exposure to pigs and often results in very severe disabilities (definitive deafness and ataxia in 50% of cases). we report the case of an employee in a rendering plant whose initial symptom was deafness. a detailed analysis of medical and veterinary literature is provided concerning the epidemiology of the disease, the clinical forms in man, bacteri ... | 1992 | 1432301 |
| persistent diplopia following streptococcus suis type 2 meningitis. | | 1992 | 1433136 |
| testing meningeal strains of streptococcus suis to detect m protein genes. | previous reports have suggested that the surface proteins found in meningeal strains of streptococcus suis might be similar to the m protein of group a streptococci. fifty-five strains of s suis, including human and swine meningeal and pneumonic isolates, were tested for m protein genes by dna probes representing the constant domain of the 3' end of the group a, m protein gene. none of the s suis strains examined was positive, indicating that these organisms either lack m protein genes or harbou ... | 1992 | 1439214 |
| identification and composition of the tonsillar and anal enterococcal and streptococcal flora of dogs and cats. | enterococcus faecalis was the most frequently isolated enterococcal species from anal swabs and tonsils of dogs and cats, although in the anal samples from dogs ent. hirae was found almost as often as ent. faecalis. most ent. faecium strains from dog tonsils differed from those associated with humans and other animals in that they fermented sorbitol. typical ent. avium as well as atypical ent. avium-like strains were seen in dogs, while the related species ent. raffinosus was associated with cat ... | 1992 | 1447058 |
| [acute mortality in pigs caused by streptococcus suis type 1]. | in early 1991 many young pigs died without clinical signs on a farm in the province of utrecht. this article describes the isolation of streptococcus suis type 1 after postmortem examination of the piglets. | 1992 | 1462345 |
| studies on a murine model for evaluation of virulence of streptococcus suis capsular type 2 isolates. | five different parameters, time of incubation of the culture, type of culture medium, inoculum, strain of inbred mice, and age of mice, were tested using the ld50 technique to standardize a murine model for the evaluation of the virulence of streptococcus suis capsular type 2 isolates. a model using 28 day-old mice belonging to cf1 strain appeared to give the best results. the inoculum size was the parameter most influencing the 50% lethal dose obtained with mice. inoculation with 1-ml volume of ... | 1992 | 1490593 |
| production and characterization of two streptococcus suis capsular type 2 mutants. | two avirulent mutants of streptococcus suis capsular type 2 (m2 and m42) were produced from a highly virulent strain. mutant m2, obtained after serial subcultures of the parent strain in the presence of rabbit anti-capsular type 2 serum, no longer possessed the type-specific capsular antigen, as demonstrated by serotyping methods and immunoelectron microscopy. the lancefield group d antigen could not be detected on the cell surface of this mutant using the immunogold labelling technique. sds-pag ... | 1992 | 1536064 |
| an investigation of bacterial causes of arthritis in slaughter hogs. | joints from 153 arthritic and 80 normal slaughter hogs were examined by culture for presence of bacteria. although none of the normal joints yielded bacteria, 37% of the disease joints were positive for bacterial growth. of 67 bacterial isolates obtained, 45% were erysipelothrix rhusiopathiae. occurrence of other bacteria in order of their frequency was streptococcus suis (16%), actinomyces pyogenes (10%), mycoplasma spp. including 3 m. hyorhinis isolates (7%), staphylococci (7%), streptococcus ... | 1992 | 1554766 |
| phenoxymethyl penicillin potassium as an in-feed medication for pigs with streptococcal meningitis. | in two separate studies involving 2500 weaner pigs, strategic infeed medication with phenoxymethyl penicillin potassium significantly reduced the incidence of streptococcal meningitis. | 1992 | 1557880 |
| cloning and nucleotide sequence of the gene encoding the 136-kilodalton surface protein (muramidase-released protein) of streptococcus suis type 2. | we cloned and sequenced the gene encoding the muramidase-released protein (mrp) of a pathogenic streptococcus suis type 2 strain to determine whether its amino acid sequence resembles that of proteins with known functions and to determine its function in virulence. the complete nucleotide sequence composing the gene and the regions flanking it was determined. the deduced amino acid sequence revealed the presence of a signal peptide at the n terminus and a cell envelope anchor at the c terminus, ... | 1992 | 1587602 |
| streptococcus suis infections in horses and cats. | | 1992 | 1604787 |
| antimicrobial resistance patterns and plasmid profiles of streptococcus suis isolates. | streptococcus suis isolates recovered from diseased animals in quebec and western canada and from human cases in europe were tested for their susceptibility to different antimicrobial agents and screened for their plasmid content. most isolates from quebec were clindamycin, erythromycin, and tetracycline resistant; animal isolates from western canada were notably less resistant to clindamycin and erythromycin, whereas human isolates were considerably more susceptible to most antimicrobials teste ... | 1992 | 1616981 |
| porcine streptococcus suis in minnesota. | | 1992 | 1616988 |
| primary prevention of streptococcus suis meningitis. | | 1991 | 1682567 |
| virulence of streptococcus suis type 2 strains in newborn germfree pigs depends on phenotype. | to determine whether the virulence of streptococcus suis type 2 is associated with the phenotype of the strain, we infected newborn germfree pigs with 10 strains of s. suis type 2 categorized by three phenotypes. in an earlier study, the phenotypes were distinguished by the presence or absence of the muramidase-released protein (mrp) and an extracellular factor (ef) and were designated mrp+ ef+, mrp+ ef- and mrp- ef-. pigs were first inoculated with bordetella bronchiseptica to predispose them t ... | 1992 | 1730489 |
| characterization of six new capsular types (23 through 28) of streptococcus suis. | six new capsular types of streptococcus suis (types 23 to 28) are described. all reference strains were isolated from diseased pigs and were morphologically and biochemically similar to previously described capsular types 1 to 22. clear and specific reactions were obtained for each of the new capsular types with three different typing techniques; no cross-reactions were detected among them or with other s. suis capsular types. their capsular material presented similar ultrastructural characteris ... | 1991 | 1774266 |
| a case of human endocarditis due to streptococcus suis in north america. | | 1991 | 1775866 |
| experimental infections of mice and pigs with streptococcus suis type 2. | five inbred strains of mice were tested for their susceptibility to streptococcus suis type 2 including the type strain, two isolates from meningitis in pigs and two isolates from tonsils of clinically healthy pigs. c57bl/6, icr and ddy strain mice showed lower susceptibility to all strains of s. suis type 2 than balb/c and ss strain mice. the type strain and the isolates from diseased pigs produced septicaemia and meningitis in balb/c and ss mice inoculated with 10(8) colony forming unit of the ... | 1991 | 1790214 |
| the site of the lesion causing hearing loss in bacterial meningitis: a study of experimental streptococcal meningitis in guinea-pigs. | the pathological basis of hearing loss in bacterial meningitis was investigated using an animal model of streptococcus suis meningitis. forty guinea-pigs were infected after their hearing had been assessed by brain stem auditory evoked potentials. in 17 animals, it was possible to repeat the procedure at the onset of meningitis; this included one animal with subclinical disease. fifteen animals showed evidence of hearing loss, which on subsequent histological examination was found to be associat ... | 1991 | 1800912 |
| an abattoir survey of pneumonia and pleuritis in slaughter weight swine from 9 selected herds. iv. bacteriological findings in chronic pneumonic lesions. | a total of 855 pig lungs were collected at slaughter and evaluated macroscopically. bacteriological examinations were carried out on tissue samples from chronic pleuropneumonic lesions (n = 196) and from chronic bronchopneumonic lesions with suppuration (n = 14). samples from normal lung tissue (n = 22) were also included. pasteurella multocida was isolated from 54%, actinobacillus (haemophilus) pleuropneumoniae from 11%, and streptococcus spp. from 14% of the pneumonic lesions, respectively. fr ... | 1991 | 1814189 |
| a longitudinal study of natural infection of piglets with streptococcus suis types 1 and 2. | streptococcus suis types 1 and 2 were detected in nasal swabs taken from five litters of piglets sampled twice weekly from birth. the two types had been detected in all pigs by the time they were 38 and 25 days old respectively with mean ages of first detectable infection being 13.5 and 8.5 days. the prevalence of infection was not affected by housing conditions or the population density of pigs. piglets originating from a sow with vaginal swabs positive for s. suis type 2 were infected earlier ... | 1991 | 1879478 |
| identification of two proteins associated with virulence of streptococcus suis type 2. | the protein profiles of various cell fractions of 180 strains of streptococcus suis type 2, which were isolated from diseased pigs, from healthy pigs when they were slaughtered, and from human patients, were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting. the isolates from diseased pigs contained two proteins that were absent in most of the isolates from healthy pigs. one of these proteins was a 136-kda protein that was previously identified as the muram ... | 1991 | 1879937 |
| adherence of streptococcus suis capsular type 2 to porcine lung sections. | the present study was undertaken to evaluate the ability of 33 streptococcus suis capsular type 2 isolates to adhere to frozen sections of porcine lung. twenty isolates originated from diseased pigs and 13 from the nasal cavities of clinically healthy pigs. all isolates from diseased animals adhered to lung sections; isolates from pneumonia adhered, in general, in greater numbers than isolates from meningitis. only four isolates from clinically healthy animals showed a weak adherence to lung sec ... | 1991 | 1889041 |
| identification of epidemic strains of streptococcus suis by genomic fingerprinting. | a natural outbreak of streptococcus suis meningitis in two closed swine herds was studied. dna fingerprinting, serotyping, and biochemical profiles were assessed. multiple serotypes were recovered from these herds. in farm a, 50 s. suis strains were isolated from 330 swabs collected. eighteen strains belonged to serotype 2, and 32 strains belonged to serotypes 3, 5, 6, 8, 9, and 11. in farm b, 16 s. suis strains were recovered from a total of 70 samples. eight strains belonged to serotype 7 and ... | 1991 | 1890177 |
| susceptibility of streptococcus suis to penicillin. | | 1991 | 1892937 |
| fatal streptococcus suis meningitis in man. | a case of streptococcus suis meningitis is observed in a 39-year-old and previously healthy meat factory worker. neurological recovery was incomplete despite adequate and sustained antimicrobial therapy. early deafness was demonstrated by brainstem auditory evoked potentials. death due to aspiration pneumonia, cardiac arrest and subsequent cerebral anoxia occurred late in the course of the illness. | 1991 | 1927255 |
| colonization of the pharyngeal tonsil and respiratory tract of the gnotobiotic pig by a toxigenic strain of pasteurella multocida type d. | seven-day-old gnotobiotic pigs were inoculated intranasally with pasteurella multocida and euthanatized 2, 5, 9, and 14 days after inoculation. tissues from the oropharynx and respiratory tract of pigs were cultured quantitatively and analyzed microscopically. pigs remained afebrile and alert, except one that died of acute fibrinopurulent pneumonia. pasteurella multocida was isolated in greatest numbers from the pharyngeal tonsils, but only in low numbers from turbinate, trachea, lung, spleen, a ... | 1991 | 1949505 |
| detection of streptococcus suis type 2 in tonsils of slaughtered pigs using improved selective and differential media. | new selective and differential media were devised for the isolation and identification of streptococcus suis type 2. the selective medium (nncc) agar) was todd-hewitt broth containing 1.5% bactoagar and 5% defibrinated sheep blood with addition of sodium azide (50 micrograms/ml), nalidixic acid (25 micrograms/ml), colistin (12.5 micrograms/ml) and crystal violet (2 micrograms/ml). the differential medium consisted of heart infusion agar and antiserum specific only for s. suis type 2. in a total ... | 1991 | 1949547 |
| bèta-hemolytic streptococci from pigs: bacteriological diagnosis. | bèta-hemolytic streptococci from lesions in pigs were identified as s. dysgalactiae biotype "equisimilis" and s. dysgalactiae serovar l, s. porcinus, s. agalactiae, e. faecalis and co2 dependent and broad bèta-hemolytic s. suis. data are provided which can be used in the interpretation of commercial identification systems. tests results and physiological characteristics which complete identification procedures using coagglutination tests are proposed and discussed. | 1991 | 1950251 |
| ultrastructural study of surface components of streptococcus suis. | the presence of capsular material on cells of nine reference strains of streptococcus suis representing serotypes 1 to 8 and 1/2 was determined by transmission electron microscopy after polycationic ferritin labeling, immunostabilization, or fixation with a combination of glutaraldehyde and lysine. all the cells of the reference strains examined were covered with a layer of capsular material whose thickness varied between 20 to 30 nm and 350 to 375 nm when examined by immunostabilization. capsul ... | 1990 | 1971617 |
| hemagglutination properties of streptococcus suis. | a total of 49 strains (23 reference strains and 26 field isolates) of streptococcus suis were tested for their ability to agglutinate erythrocytes from different animal species. ten different hemagglutination patterns were established. thirty-three strains (67%) did not agglutinate any of the erythrocytes tested; sixteen strains (33%) agglutinated erythrocytes from one or more animal species. different strains belonging to the same capsular type presented different hemagglutination patterns. no ... | 1990 | 1977767 |
| characterization of prototype and clinically defined strains of streptococcus suis by genomic fingerprinting. | a collection of streptococcus suis strains from animal and human infections was examined for dna-banding patterns after restriction endonuclease digestion and agarose gel electrophoresis. the endonuclease haeiii produced the most discriminating restriction profiles among 23 serotypes studied. dna from serotypes 9, 11, 12, and 16 was resistant to haeiii cleavage. dna from serotypes 9 through 16 was cleaved with hindiii and showed substantial genomic differences. we also examined 106 epidemiologic ... | 1990 | 1979331 |
| characteristics of different streptococcus suis ecovars and description of a simplified identification method. | streptococcus suis strains associated with different animal hosts or located in different body regions constitute special ecovars of s. suis. a group of co2-dependent strains which showed several unusual traits was found in the genital tract of swine, and mannitol- and sorbitol-fermenting strains were isolated from sheep, cattle and horses. s. suis was found to be biochemically more heterogenous than originally described. a detailed description is given of additional characteristics of the speci ... | 1991 | 2024436 |
| evaluation of methods used for detecting streptococcus suis type 2 in tonsils, and investigation of the carrier state in pigs. | streptococcus suis type 2 was isolated from the tonsils of 143 (76 per cent) of 188 pigs from three herds by culturing on media containing a specific antiserum. culture of frozen sections of tonsillar tissue was more sensitive than culture of swabs or deep scrapes. the specificity of an indirect fluorescent antibody test for identifying s suis type 2 in mixed cultures was conservatively estimated to be 0.89. the level of infection in one herd without a history of meningitis was lower than in two ... | 1991 | 2034898 |
| superoxide dismutases of pathogenic and non-pathogenic streptococcus suis type 2 isolates. | pathogenic and non-pathogenic isolates of streptococcus suis type 2 were screened to determine whether differences in superoxide dismutase (sod) synthesis could explain the observed differences in their pathogenicity and intracellular fate in macrophages. a single band of sod activity of similar rf value was visualised in page gels in all isolates and inhibition studies suggested that the cofactor present was manganese. there was no correlation between specific sod activity and virulence. it is ... | 1991 | 2037239 |
| isolation and characterization of streptococcus suis capsular types 9-22. | the incidence and biochemical patterns of streptococcus suis capsular types 9-22 are presented. of 148 untypeable (with types 1-8 antisera) isolates of s. suis recovered from diseased pigs, 10% were not capsulated. of the remaining 134 isolates, only 53% belonged to capsular types 9-22; capsular types 22 and 9 were the most prevalent, representing 19% and 13%, respectively. capsular type 15 (de moor's group t streptococcus) is reported here for the first time in north america since it was descri ... | 1991 | 2039790 |
| pneumonia in a sow due to streptococcus suis type ii and bordetella bronchiseptica. | | 1991 | 2063536 |
| streptococcus suis septicaemia presenting as severe acute gastro-enteritis. | | 1991 | 2071918 |
| an update on streptococcus suis identification. | | 1990 | 2094457 |
| [deafness-blindness caused by streptococcus suis meningitis--epidemiology and rehabilitation]. | a case of blind-deafness due to streptococcus suis meningitis is described. the high incidence of blind-deafness in this disease is emphasized. rehabilitation problems are discussed. special attention is given to the lorm writing as an ideal way of revalidation in this particular patient. | 1990 | 2146855 |
| relationship between intracellular survival in macrophages and pathogenicity of streptococcus suis type 2 isolates. | naturally-occurring streptococcus suis type 2 meningitis affects pigs and man; experimental models of the disease have also been established in pigs and mice. a sustained, high-level bacteraemia is an important phase preceding the development of s. suis type 2 meningitis. the main cellular clearance mechanism for circulating bacteria is the resident hepatic and splenic macrophages. the interaction between various isolates of s. suis type 2 and murine macrophages was investigated to determine whe ... | 1990 | 2199755 |
| streptococcus suis serotypes associated with disease in weaned pigs. | streptococcus suis was recovered from 9 outbreaks of septicaemia and meningitis in weaned pigs between 1979 and 1983. fifteen isolates from 7 outbreaks were identified as s. suis type 9, and 3 isolates from 2 outbreaks as s. suis type 2. three further isolates of s. suis type 2 and an isolate of s. suis type 3 were recovered from cases of bronchopneumonia in weaned pigs from 4 other piggeries. | 1990 | 2222362 |
| infective endocarditis caused by streptococcus suis serotype 2. | infective endocarditis caused by streptococcus suis serotype 2 is not uncommon in pigs but is rare in human beings. we describe the case of a pig-farmer with endocarditis due to s. suis serotype 2 and in whom prolapse of the mitral valve was the predisposing cardiac lesion. streptococcus suis, a possible cause of infective endocarditis in endemic areas, may be confused with other group d streptococci. in suspected cases a history of contact with pigs or raw pork should be sought. | 1990 | 2230181 |
| pathology of streptococcal meningitis following intravenous intracisternal and natural routes of infection. | the distribution of pathological lesions present in 20 cases of naturally-occurring streptococcus suis type 2 meningitis and 20 cases of the disease induced experimentally by intravenous or intracisternal inoculation was examined. it was found that the distribution of lesions was similar; mild lesions were present at the choroid plexuses whilst the most dense cellular accumulations were found at sites of cerebrospinal fluid (csf) efflux, such as arachnoid villi and olfactory nerve sheaths. the d ... | 1990 | 2234313 |
| experimental studies on the comparative infectivity and pathogenicity of streptococcus suis type 2. i. porcine and human isolates in pigs. | piglets between 1 and 40 days of age were inoculated with varying numbers and with different isolates of streptococcus suis type 2 by the intranasal, intravenous and subarachnoid routes. less than 100 organisms of an isolate cultured from apparently normal pigs caused subclinical infection in 1-day-old piglets after intranasal inoculation. this infection was naturally transmitted between litter mates. intravenous inoculation of a similar isolate in 7-week-old pigs resulted in a sub-clinical bact ... | 1990 | 2249710 |
| experimental studies on the comparative infectivity and pathogenicity of streptococcus suis type 2. ii. porcine and human isolates in laboratory animals. | mice, rats, guinea-pigs and rabbits were inoculated with isolates of streptococcus suis type 2. an isolate cultured from the tonsils of a healthy pig, produced disease in rabbits after intravenous inoculation but not in mice, rats or guinea-pigs. an isolate of s. suis type 2, that was pathogenic for pigs and had been cultured from a human patient with clinical disease, produced signs of neurological disease in mice, rats and rabbits following intravenous inoculation. there was an apparent dose r ... | 1990 | 2249711 |
| efficacy of tiamulin against experimentally induced streptococcus suis type-2 infection in swine. | eighteen 4-week-old pigs were used in a study to evaluate tiamulin in drinking water for control of experimentally induced streptococcus suis type-2 infection. pigs in groups a and b (n = 6 pigs/group) were aerosolized with a logarithmic-growth phase culture of s suis type 2, whereas pigs in group c (n = 6 pigs) served as noninfected and nonmedicated controls. after exposure to s suis, pigs in group b were given 180 mg of tiamulin/l of drinking water for 5 days. pigs in group b consumed more fee ... | 1990 | 2272877 |
| immunisation of pigs with killed cultures of streptococcus suis type 2. | ten intravenous inoculations of 10(10) formalin-killed pathogenic streptococcus suis type 2 stimulated detectable levels of opsonic antibody and a strong protective response against intravenous challenge with 10(9) viable s suis type 2 of the same strain. heat-killed organisms did not stimulate a protective response, even though the type-specific antigen was intact and opsonic antibodies were induced. when the number of formalin-killed organisms in the inoculum was increased 10-fold, one inocula ... | 1990 | 2300710 |
| streptococcus suis infection in swine. a sixteen month study. | a total of 349 isolates of streptococcus suis retrieved from different tissues from diseased pigs were examined in this study. only 48% of them could be categorized as one of serotypes 1 to 8 and 1/2. among typable isolates, serotype 2 was the most prevalent (23%), followed by serotype 3 (10%). the majority of all isolates originated from lungs, meninges/brain, and multiple tissues. forty-one percent of typable isolates and 33% of untypable isolates were retrieved in pure culture. other isolates ... | 1990 | 2306668 |
| prevalence of streptococcus suis in four to eight week old clinically healthy piglets. | the study was undertaken to determine the prevalence, in the nasal cavities, of streptococcus suis in four to eight week old clinically healthy piglets. streptococci biochemically compatible with s. suis were isolated from 94% of piglets and 98% of farms. of the 782 isolates submitted to serotyping, only 164 (21%) were included in the nine official serotypes. these 164 typable isolates originated from 121 (31%) of the 388 piglets and from 36 (73%) of the 49 farms included in the study. the most ... | 1990 | 2306669 |
| in vitro susceptibility of selected veterinary bacterial pathogens to ciprofloxacin, enrofloxacin and norfloxacin. | the minimum inhibitory concentrations (mic) of ciprofloxacin, enrofloxacin, and norfloxacin were tested for approximately ten clinical isolates of each of actinobacillus pleuropneumoniae, actinobacillus suis, actinomyces pyogenes, corynebacterium pseudotuberculosis, erysipelothrix rhusiopathiae, haemophilus parasuis, haemophilus somnus, pasteurella haemolytica, pasteurella multocida, rhodococcus equi, streptococcus equi, streptococcus suis and streptococcus zooepidemicus. ciprofloxacin and enrof ... | 1990 | 2306672 |
| effects of experimentally induced streptococcus suis infection on the pharmacokinetics of penicillin g in pigs. | the pharmacokinetics of potassium penicillin g were studied in both healthy (n = 8) and experimentally streptococcus-suis-infected (n = 6) pigs following intramuscular administration (15,000 iu/kg). streptococcus-suis infection was induced artificially in young cross-bred pigs by subcutaneous inoculation with 9 x 10(8) to 10(9) colony-forming units of s. suis. the rectal temperature of infected pigs was significantly increased (p less than 0.01) before penicillin g injection and this was maintai ... | 1990 | 2319635 |
| isolation and characterization of temperature-sensitive mutants of streptococcus suis: efficacy trial of the mutant vaccine in mice. | a model of experimental streptococcus suis infection was developed in young mice. minimum lethal dose (mld) values were calculated for four virulent serotypes (1/2, 1, 2, 3) of s. suis using this model. temperature-sensitive (ts) mutants of s. suis serotypes 1/2 and 1-8 were isolated and characterized on the basis of their growth kinetics and reversion rates. ts mutants of s. suis 1/2, 1, 2, and 3 were tested as vaccines against the virulent homologous and heterologous challenges in mice. the pr ... | 1990 | 2353447 |
| pathogenesis of meningitis caused by streptococcus suis type 2. | the neuraxes of 26 pigs inoculated intravenously with a pathogenic isolate of streptococcus suis type 2 and killed 17-47 h later were examined using histologic and scanning microscopic techniques. the only pathologic lesions detected in all pigs were associated with the choroid plexus: disruption of the plexus brush border, a decrease in the number of kolmer cells, and exudation of fibrin and inflammatory cells into the ventricles. lesions affecting the cerebral and choroid plexus endothelium, s ... | 1990 | 2373874 |
| [fulminant sepsis caused by streptococcus suis]. | a 26-year-old man, in daily contact with pigs was admitted to hospital with septic shock which appeared to be caused by streptococcus suis type 2 infection. despite immediate antibiotic therapy a multiple organ failure developed, with ards, cardiac failure, disseminated intravascular coagulation and acute renal failure. streptococcus suis infection is a zoonosis. the bacterium can be isolated from the tonsils of a significant part of the dutch pig population. mainly people who are in close conta ... | 1990 | 2385312 |
| protective effect of sera raised against different fractions of streptococcus suis type 2. | five bands of 44, 54, 78, 86 and 94 kd were identified by western blot analysis of streptococcus suis type 2 by the use of sera that were from immune or non-immune pigs and were positive or negative in bactericidal tests in vitro. these bands were cut from the gels and used as antigens to produce antisera in rabbits. rabbit sera against the 78 and 94 kd bands were positive in bactericidal tests, and the serum against the 94 kd band also protected mice against challenge with a live pathogenic str ... | 1990 | 2394850 |
| streptococcus suis meningitis in a horse. | | 1990 | 2399640 |
| description of 14 new capsular types of streptococcus suis. | fourteen new capsular types of streptococcus suis (types 9 to 22) are described. all reference strains are morphologically and biochemically similar to types previously described. reference strain types 9 to 13, 15, 16, and 22 were isolated from diseased pigs, whereas types 17 to 19 and 21 came from clinically healthy pigs; type 14 was isolated from a human case of meningitis, and type 20 was isolated from a diseased calf. the group t streptococcus of de moor has been included in the typing syst ... | 1989 | 2480359 |
| hemagglutination activities of group b, c, d, and g streptococci: demonstration of novel sugar-specific cell-binding activities in streptococcus suis. | a total of 378 streptococcal isolates of lancefield groups b, c, d and g were tested for their ability to hemagglutinate untreated, sialidase-treated, and endo-beta-galactosidase-treated human erythrocytes. of the 43 strains showing positive hemagglutination, 9 were inhibitable with neutral monosaccharides. four strains were inhibited with galactose and n-acetylgalactosamine, whereas five were inhibited with galactose only. a third, sialic acid-specific adhesion activity was suggested for two ad ... | 1989 | 2492258 |
| fatal streptococcus suis septicemia in an abattoir worker. | a 51-year-old abattoir worker became ill with high fever and was admitted to hospital late in the evening, where he died 4 h later. smears of peripheral blood taken 7 h after death showed numerous cocci. cultures of the blood grew beta-hemolytic streptococci exhibiting the biochemical properties of streptococcus suis ii. a complete autopsy with extensive microscopical studies showed numerous bacteria in small vessels of several organs, but no bacterial colonisation of tissues, meningitis, or oth ... | 1989 | 2497004 |
| streptococcus suis meningitis, permanent perceptive deafness and endophthalmitis. | | 1989 | 2607048 |
| streptococcus suis isolated from pigs in south australia. | | 1989 | 2619656 |
| [type 2 streptococcus suis (r-streptococci) as pathogens of occupational diseases. report of a case and a review of the literature]. | report on the second human case of a streptococcus suis type 2 (group r streptococci) infection in the gdr. the patient, a 33-year-old butcher, fell ill with an acute meningitis and an initial myocarditis. group r streptococci were isolated from cerebrospinal fluid and blood. the patient was treated with penicillin g, ampicillin and gentamicin, followed by trimethoprim-sulfamerazine. both, meningitis and myocarditis disappeared and the patient recovered completely. the disease was recognized as ... | 1989 | 2652899 |
| prevalence of streptococcus suis types 1 and 2 in domestic pigs in australia and new zealand. | using an indirect fluorescent antibody test, 54 per cent of 734 palatine tonsils of conventional pigs slaughtered in australia and new zealand were found to be infected with streptococcus suis type 1 and 73 per cent of 959 were infected with s suis type 2. variations in the prevalence of infection in pigs from different herds were thought to be due to differences in the sample sizes rather than to real differences in the prevalence between herds. the prevalence of infection with s suis was simil ... | 1989 | 2658296 |
| immunisation of pigs with streptococcus suis type 2. | | 1989 | 2750048 |
| two cases of streptococcus suis meningitis. | | 1989 | 2751936 |
| studies of the protective effect of different fractions of sera from pigs immune to streptococcus suis type 2 infection. | inoculation of mice with high doses of streptococcus suis type 2 caused depression, anorexia, lethargy and sometimes death. this was prevented by prior inoculation of whole immune pig serum, the igm and igg fractions of immune pig serum and serum enriched with antibody to surface antigens. clinical signs were not prevented by prior inoculation of pre-immune serum or serum depleted of antibody to surface antigens. serum fractions that were protective in vivo were also opsonic in vitro. western bl ... | 1989 | 2760276 |
| streptococcus suis type 2--an underdiagnosed zoonotic agent? | | 1989 | 2761469 |
| in vitro antimicrobial activity of sulfonamides against some porcine pathogens. | the minimal inhibitory concentrations (mic) of sulfonamides were determined against bordetella bronchiseptica (n = 10), pasteurella multocida (n = 10), haemophilus pleuropneumoniae (n = 20), and streptococcus suis (n = 10) strains isolated from pigs with atrophic rhinitis, pneumonia, or meningitis. sulfonamides tested in an agar dilution method were sulfachloropyridazine, sulfadiazine, sulfadimethoxine, sulfamethazine, sulfadoxine, sulfisoxazole, sulfamerazine, sulfamethoxazole, sulfamethoxypyri ... | 1989 | 2774319 |
| differences in virulence between two strains of streptococcus suis type ii after experimentally induced infection of newborn germ-free pigs. | fifteen newborn germ-free pigs were inoculated with 2 strains, d-282 and t-15, of streptococcus suis type ii. some pigs also were preinoculated with bordetella bronchiseptica, which successfully predisposed them to s suis infection. the 2 streptococcal strains were differentiated by muramidase treatment, which released certain high molecular-weight proteins, termed muramidase-released proteins (mrp), from the cell wall of strain d-282, but not from the cell wall of strain t-15. only strain d-282 ... | 1989 | 2774320 |
| occupational exposure to streptococcus suis type 2. | antibody titres to streptococcus suis type 2 were measured with an enzyme linked immunosorbent assay (elisa) in four occupational groups in new zealand. no veterinary students, 9% of dairy farmers, 10% of meat inspectors and 21% of pig farmers were seropositive to s. suis type 2. the development of antibody to s. suis type 2 was associated with occupational contact with pigs or their meat products. subclinical infection with s. suis type 2 appears to occur in humans and the antibody produced is ... | 1989 | 2776849 |
| monoclonal antibodies for coagglutination of streptococcus suis type 1. | monoclonal antibodies (mabs) were sought that would identify streptococcus suis. spleen cells from balb/c mice immunized with formalin-killed s. suis were fused with the murine cell-line sp-2/0. hybridomas positive for s. suis were identified by a solid-phase radioimmunoassay with a mixture of all available serotypes of s. suis. on further screening with individual serotypes of s. suis (types 1, 2, 1/2, 3, 4, 5, 7, 8, 9 and 12) and other related and unrelated bacteria, a hybridoma specific for t ... | 1989 | 2800308 |
| rapid detection of streptococcus suis serotype 2 in weaned pigs. | a survey to detect streptococcus suis serotype 2 in 1,716 weaned pigs was done in quebec. forty-nine sow herds were included in this survey: in 26 herds, s suis serotype 2 had been isolated during the preceding 12 months and in 23 herds (control), the organism had not been detected during a previous study. swab specimens of the nasal cavity and tonsils of pigs were obtained for bacteriologic culture, and s suis serotype 2 was easily detected by the use of brain-heart infusion agar containing a s ... | 1989 | 2802297 |
| bacterial endocarditis caused by streptococcus suis type 2. | | 1989 | 2915176 |
| kill kinetics of the cephalosporin antibiotics cephalexin and cefuroxime against bacteria of veterinary importance. | kill kinetic studies for two cephalosporin antibiotics, cephalexin and cefuroxime were carried out against veterinary strains of escherichia coli, pasteurella multocida, streptococcus suis, erysipelothrix rhusiopathiae and a laboratory culture of staphylococcus aureus. in more than 90 per cent of cases a kill of more than 99 per cent was achieved within four hours of antibiotic treatment at concentrations of 2 or 4 micrograms/ml. although cefuroxime was effective at lower concentrations than cep ... | 1988 | 3057718 |
| isolation of streptococcus suis from diseased pigs in canada. | a total of 260 isolates of streptococci collected over a 9-year period from diseased pigs submitted for necropsy were studied. seventy-seven percent of isolates were identified as s. suis and 32% of s. suis isolates were retrieved in pure culture. s. suis was found more frequently in lungs and was often isolated in conjunction with actinobacillus pleuropneumoniae, pasteurella multocida, escherichia coli and other microorganisms. a total of 151 (76%) of s. suis isolates could be serotyped within ... | 1988 | 3176314 |
| [systemic infection caused by streptococcus suis]. | streptococcus suis type 2 was isolated from blood and cerebrospinal fluid in a 49-year-old butcher as the causative organism of a generalized septic infection with meningeal involvement. high-dosage penicillin g treatment quickly terminated the fever and all neurological signs disappeared completely. streptococcus suis type 2 causes a zoonosis, which usually occurs as an occupational disease among those handling pigs or pork (farmers, butchers etc.). sequelae of such infection not rarely are dam ... | 1988 | 3181015 |
| streptococcus suis isolated from pigs in finland. | | 1988 | 3202064 |
| immunisation of pigs with live cultures of streptococcus suis type 2. | repeated intravenous injections of pigs with live virulent cultures of streptococcus suis type 2 stimulated a strong protective response against subsequent challenge. this protection was transferred passively to susceptible pigs by the inoculation of sera from protected pigs. a strong protective response was also stimulated by repeated inoculations of live cultures of non-pathogenic isolates. the protective response did not eliminate s suis type 2 organisms already established in the tonsils or ... | 1988 | 3212282 |
| a murine model of streptococcus suis type 2 meningitis in the pig. | when young or adult mice were infected experimentally with isolates of streptococcus suis type 2 of known pathogenicity for pigs, the organisms produced disease, young mice being more susceptible than adults. an isolate of s suis type 2 less pathogenic for pigs also appeared less pathogenic in mice. the organism could be reisolated from infected mice for up to 42 days. inoculum size was one factor influencing the likelihood of an individual mouse developing meningitis following intravenous inocu ... | 1988 | 3212289 |
| streptococcus suis and other streptococcal species as a cause of extramammary infection in ruminants. | | 1988 | 3218040 |
| meningitis caused by streptococcus suis in humans. | between 1968 and 1984, 30 strains of streptococcus suis causing meningitis were isolated in the netherlands. twenty-eight strains were type 2, one was type 4, and one was untypable. the average age of the patients infected with these strains was 49 years (range, 21-76 years); the male-to-female ratio was 6.5. twenty-five patients (83%) were employed in the pork industry. two patients (7%) died. in seven cases (23%), predisposing factors were identified. the most frequent sequela was hearing loss ... | 1988 | 3353625 |
| streptococcus suis type 1 infection of sucking pigs. | | 1988 | 3355456 |
| bacterial endocarditis presenting as acute monoarthritis. | the presentation of a pig farmer with acute arthritis of the shoulder, cardiac murmurs, and streptococcus suis growing on blood cultures highlights one of the rheumatological presentations of bacterial endocarditis. the need for a thorough general medical examination together with synovial fluid and blood culture in patients with acute monarthritis is emphasised. the suggestion that acute arthritis related to endocarditis is in nature truly septic, rather than mediated by circulating immune comp ... | 1988 | 3401056 |
| streptococcus suis bacteraemia. | streptococcus suis is a zoonotic pathogen which causes meningitis, arthritis and septicaemia in pigs, and rarely meningitis or septicaemia in humans. this organism has recently been isolated from pigs in new zealand, where it appears to be widely distributed in pig herds. this case is the first report of human infection in new zealand. | 1987 | 3452149 |
| gross and histopathological findings in unusual lesions caused by streptococcus suis in pigs. i. cardiac lesions. | unusual lesions caused by streptococcus suis involved the heart of 48 pigs necropsied over a four-year period. lesions included fibrinopurulent pericarditis (six pigs), hemorrhagic, necrotizing myocarditis resembling mulberry heart disease (21 pigs), and vegetative valvular endocarditis (21 pigs). histologically, the myocarditis was characterized by focally extensive and diffuse hemorrhages and necrosis, with infiltrations of neutrophils and mononuclear cells, and thrombosis of small and large m ... | 1987 | 3453268 |
| gross and histopathological findings in unusual lesions caused by streptococcus suis in pigs. ii. central nervous system lesions. | subacute meningoencephalitis or meningoencephalomyelitis caused by streptococcus suis was diagnosed in 53 pigs over a four-year period. affected pigs averaging 11 weeks of age with a range from five days to 26 weeks, had been treated with antibiotics and had partially recovered. hyperemia of meningeal vessels and modest increase in cerebrospinal fluid were the most common gross central nervous system lesions. histologically, fibrin, edema and a mixture of inflammatory cells were present in menin ... | 1987 | 3453269 |
| streptococcus suis type 2--a zoonotic agent in new zealand. | | 1986 | 3457300 |