| bacteriological findings in materials from patients with nonspecific odontogenic infections. | the results of bacteriological studies made between 1964 and 1971 by workers at the varia laboratory, institute of medical microbiology on 767 patients treated at the clinic of gnathofacial surgery, department of medicine, friedrich schiller university at jena, are evaluated. the testees (x=275) were included in groups with specific diagnoses, and a breakdown was made according to the detection of aerobic pus-forming germs. gram-positive cocci were detected in 92% of the cases and their pathogen ... | 1976 | 7062 |
| development and resistance of staphylococci in bulgaricus milk. | studied was the dynamics of development of 9 strains of staphilococci isolated from humans and animals, kept in heat-treated milk, and their resistance in bulgarian sour milk. it was established that the pathogenic staph. aureus and staph. epidermidis develop will in fresh milk kept up to 7 days at 2--6degreesc and 18--22degreesc. in the production of bulgarian sour milk staph, aureus was shown to be viable, remaining active for seven days at 2 to 6degreesc. at room temperature (18--22degreesc) ... | 1976 | 7875 |
| approach to a practical method for screening and identifying microorganism genera from urine (author's transl). | in this study the author reported upon a practical new system for screening and identifying the microbial agents causing urinary tract infections. this system is composed of a combination of 3 screening procedures (ph-value + nitrite-test + catalase-test) and 8 selective culture media for the purpose of genus identification within 24 hours (uripret-g). a total of 130 cultures was investigated. the employed microorganisms were mainly recovered from urine samples. they included the following speci ... | 1976 | 11179 |
| production and detection of staphylococcal elastase. | the optimum conditions were determined for the production and detection of staphylococcal elastase from staphylococcus epidermidis. optimum production and recovery took place when the dialysis membrane technique was utilized with brain heart infusion agar incubated for 44 h under 15% co2 and harvested in physiological saline. near-optimal production took place by 28 h, and this was found more useful for routine use. incorporation of elastin into the culture medium or the inoculum did not result ... | 1977 | 13041 |
| histochemical and biochemical investigations on the changes of catecholamine content in the adrenal tissue of xenopus laevis--i. effect of salt-water stress. | | 1977 | 15773 |
| the bacteriology of skin cysts. | thirty-nine clinically uninflamed cysts of the three most common varieties, epidermoid cysts, trichilemmal cysts and steatocystoma multiplex were removed under sterile conditions and the contents cultured under aerobic and anaerobic conditions. seventy-three percent of epidermoid cysts grew significant numbers of organisms whereas none of the trichilemmal cysts did so. the organisms found were the common skin commensals, staphylococcus epidermidis biotype i, anaerobic gram positive cocci of the ... | 1977 | 17428 |
| quantitative study and typization of aerobic bacteria in the conjunctival sacs of healthy eyes. | we carried out a qualitative and quantitative bacteriological research into the conjunctives of 220 subjects in good health mostly women (180) exempt from recent or previous eyes diseases. in order to gather conjunctival bacteria we employed with a few variations hadley's et al. (1973 12) method. among the calculated bacterial flora we found as the most numerous ones staphylococcus epidermidis (mean valor 1960/ml), then streptococci (480/ml), micrococci (465/ml), diphteroides (360/ml), enterococ ... | 1976 | 18118 |
| conditional killing effect of staphylococcin 1580 and repair of sublethal injury in staphylococcus aureus. | treatment of sensitive cells with staphylococcin 1580, a bacteriocin of staphylococcus epidermidis, rapidly induced gross changes in the permeability of the membrane. however, only a small fraction of the cells was killed when treated cells were plated on media containing low amounts of salts. killing was greatly enhanced by increasing the amounts of small cations incorporated in the plate medium and raising the alkalinity of the medium. the effect of cations correlated inversely with the ion ra ... | 1977 | 20837 |
| secretion of lipids induced by inhibition of peptidoglycan synthesis in streptococci. | inhibition of peptidoglycan synthesis causes an immediate and massive secretion of both newly synthesized and "old" lipids from several species of bacteria, including streptococci, staphylococcus epidermidis, and bacillus subtilis. lipid secretion occurs in the absence of detectable bacterial lysis. this novel phenomenon was examined in more detail in three strains of streptococci: s. sanguis (group h), s. pyogenes (group a), and s. pneumoniae. the secretion of lipids is specifically induced by ... | 1977 | 21168 |
| bacterial stimulation and granulocyte inhibition of granulopoietic factor production. | we attempted to determine the effect of live bacteria (staphylococcus epidermidis) on granulocyte colony-stimulating-factor production by human peripheral blood mononuclear cells (monocytes and lymphocytes) in vitro. addition of bacteria to mononuclear-cell cultures enhanced colony-stimulating-factor production by these cells, as assayed on both human and mouse bone marrow. addition of peripheral blood granulocytes to parallel cultures eliminated this enhancement effect, presumably by bacterial ... | 1977 | 21349 |
| calf liver nuclear n-acetyltransferases. purification and properties of two enzymes with both spermidine acetyltransferase and histone acetyltransferase activities. | calf liver contains two nuclear n-acetyltransferases which are separated by chromatography on hydroxylapatite. both acetyltransferase a and acetyltransferase b will transfer acetate from acetyl-coa to either histone or spermidine. the same protein catalyzes the reaction with both substrates; this is shown by a constant ratio of spermidine to histone activity over a 5,000-fold purification and identical heat denaturation kinetics for both spermidine and histone acetyltransferase activity with eac ... | 1978 | 22543 |
| the influence of adrenalectomy on monoamine oxidase and nadh cytochrome c reductase in the rat heart. | the effect of adrenalectomy on the activities of monoamine oxidase (mao), nadh cytochrome c reductase (ncr), succinate dehydrogenase, malate dehydrogenase, fumarase, nad+ nucleosidase and acid phosphatase in homogenates of rat hearts was examined. besides mao only the ncr activity increased. however, both the total and the rotenone-insensitive ncr activities increased, with that of the rotenone-insensitive being about half of the total, which indicated that the effect of adrenalectomy was exerte ... | 1977 | 22598 |
| chemical and physical factors influencing methicillin resistance of staphylococcus aureus and staphylococcus epidermidis. | | 1977 | 23376 |
| conformational study of calf brain tubulin. | | 1978 | 23729 |
| physiological conditions affecting staphylococcus aureus susceptibility to staphylococcin 1580. | loss of salt tolerance, irreversible loss of viability, inhibition of l-glutamic acid uptake and effects on the high energy state of the membrane were used as parameters to measure the injury induced by staphylococcin 1580, a bacteriocin of staphylococcus epidermidis, in susceptible cells of staphylococcus aureus oxford 209p. a small part of a growing cell population appeared to be temporarily resistant to the bacteriocin, and the cells were arrested in this stage when suspended in buffer. the p ... | 1978 | 25615 |
| acupuncture: its neurophysiological basis: an anaesthetist's foreword. | | 1978 | 29773 |
| the ph-dependence of the non-specific esterase activity of carboxypeptidase a. | the hydrolysis of the following 6 esters by bovine pancreatic carboxypeptidase a (peptidyl-l-amino-acid hydrolase, ec 3.4.12.2) has been investigated over the range ph 5--10 at 25 degrees c, ionic strength 0.2: ch3co2chrco2h (r = c6h5 (ester 3), c6h5ch2 (ester 4), 4-no2c6h4co2chrco2h (r = c6h5 (ester 5), c6h5ch2 (ester 6), ch3(ch2)2 (ester 7)), ch3ch2co2ch(ch2c6h5)-co2h (ester 9). for each ester the ph dependence of kcat/km indicates that substrate binding is controlled by an acid of pkeh = 9.2 ... | 1978 | 31187 |
| anaerobic transport of serine and 2-aminoisobutyric acid by staphylococcus epidermidis. | a membrane-bound atpase detected in extracts of anaerobically grown staphylococcus epidermidis was inhibited by a variety of compounds which inhibit atpases in other organisms. serine and 2-aminoisobutyric acid (aib) were shown to enter the organism via the same transport system. the transport of aib, the membrane potential and the transmembrane ph gradient were partially or completely abolished by the same inhibitors and also by uncoupling agents and lipid-soluble ions. it is proposed therefore ... | 1978 | 32223 |
| dopamine and chronic antipsychotic drug treatment. | | 1979 | 33409 |
| attachment of bacteria to exfoliated cells from the urogenital tract. | to establish urogenital infections, organisms must adhere to the mucosal lining. a differential adherence capacity among various bacterial species was observed when exfoliated urethral and urothelial cells were tested in an in vitro system. no difference in the adherence capacity of a particular species was observed when tested with exfoliated cells obtained from voided urine from different healthy individuals of the same sex. escherichia coli harvested directly from urine specimens of patients ... | 1979 | 34577 |
| intergeneric and intrageneric inhibition between strains of propionibacterium acnes and micrococcaceae, particularly staphylococcus epidermidis, isolated from normal skin and acne lesions. | two hundred and forty-one strains or resident skin bacteria comprising 93 isolates of propionob acterium acnes and 148 of micrococcaceae derived from 36 acne patients and 8 control subjects were screened for their ability to inhibit 32 indicator strains, including 20 strains of p. acnes and 12 strains of staphylococcus epidermidis derived from patients with all grades of acne and from normal skin. fifty-three strains (22%) showed some activity against at least one indicator strain. both broad- a ... | 1979 | 34728 |
| micro-ph and pco2 electrodes in the study of pancreatic electrolyte secretion [proceedings]. | | 1978 | 35177 |
| the microbiology of serous and mucoid otitis media. | one hundred forty-four serous and mucoid effusions were cultured for aerobic bacteria, mycoplasma pneumoniae, and virus. thirty percent of all effusions yielded an unequivocally positive culture for aerobic bacteria. although serous effusions were culture positive as often as mucoid effusions, haemophilus influenzae was isolated predominantly from serous effusions and staphylococcus epidermidis predominantly from mucoid samples. only one of 73 effusions yielded a viral isolate (herpesvirus homin ... | 1979 | 36591 |
| aerobic and anaerobic cervical flora of healthy thai women. | the bacteriologic study of the cervical flora in 50 healthy women revealed that 70% harbored mixed aerobic and anaerobic organisms. aerobic organisms alone were recovered in 15 women (30%). polymicrobial organisms were found in all but five women (in these only one aerobe was isolated per patient). the majority of patients had 1-2 anaerobes, with more than two aerobes. the common aerobes were alpha-hemolytic streptococci, staphylococcus epidermidis and lactobacilli. the most common anaerobes wer ... | 1978 | 39833 |
| virulence of genus staphylococcus. iii. studies on the pathogenicity to mice. | six representative strains of staphylococci were selected on the basis of dnase activity and inoculated into the mice to study the correlation of the presence of this enzyme to the virulence of the staphylococci. two strains of staphylococci among them produced dnase but not the free coagulase, and one of these two strains had an obvious virulence against the mice. the results of experiments suggest that there are at least certain strains which may be designated as staphylococcus aureus among th ... | 1975 | 47790 |
| studies on polysaccharide c of staphylococcus epidermidis. 2. antigenic properties. | the antigenic properties of polysaccharide c (poly c) of s. epidermidis strongly support the analytical indications that it is an n-acetylglucosaminylglycerol teichoic acid with 1:3-phosphodiester linkages. the major antigenic determinant is n-acetyglucosamine, predominantly present in the beta-configuration. also anti-glycerophosphate antibodies are produced, apparently dependent on the degree of glycosylation. purified poly c was unable to sensitize either normal or tanned sheep erythrocytes f ... | 1975 | 50716 |
| measurement of peptidoglycan antibodies by a radioimmunoassay. | staphylococcus epidermidis peptidoglycans solubilized by sonication or lysozyme digestion, and synthetic peptidoglycan analogs such as hsa-carboxymethyl-gly-l-ala-l-ala-d-ala-d-ala (hsa-pentapeptide) or l-ala-gamma-d-glu-l-lys-d-ala-d-ala (pentapeptide) have been labeled with 125i and tested for their applicability in the radioactive antigen binding assay. use of radioiodinated staph. epidermidis peptidoglycans was found to be considerably impeded by the presence of at least 2 different antigeni ... | 1975 | 52237 |
| a serial study of pregnancy proteins in primigravidae. | the plasma concentrations from four 'pregnancy proteins' and three steroid hormones have been measured throughout pregnancy in 15 primigravidae. two of the proteins, human placental lactogen (hpl) and pregnancy-specific beta1-glycoprotein (psbetag), are specific for pregnancy and correlate well with the stage of gestation. it is suggested that measurement of psbetag may be useful in assessing feto-placental wellbeing. neither of the pregnancy-associated proteins, steriod-binding beta-globulin (s ... | 1976 | 57799 |
| mouse virulent strain of staphylococcus epidermidis. relation of antiphagocytic activity to the protection-inducing antigen. | using 10(9) or 10(7) colony-forming units of a strain of staphylococcus epidermidis (strain 1142) in saline or 5% mucin, respectively, 90 to 100% of mice died within 24 to 48 hr after intraperitoneal challenge infection. these organisms gradually multiplied in the peritoneal cavity when injected intraperitoneally into mice, while the mouse avirulent strain (strain 1124) rapidly decreased and no organisms were found there 20 hr after injection. this strain was capable of inducing resistance again ... | 1976 | 61300 |
| solid-phase radioimmunoassay for detection of staphylococcal antigen in serum of rabbits with endocraditis due to staphylococcus aureus. | to aid in the rapid diagnosis of staphylococcal infection, a solid-phase radioimmunoassay for staphylococcus aureus antigen was developed and evaluated in rabbits with staphylococcal endocarditis. test specimens containing antigen were added to polystyrene tubes coated with antibody to s. aureus. antigens immobilized on the tube were detected by adding radiolabeled antibody to s. aureus. sensitivity for antigen was 0.312 microgram/ml in buffer and 1.25 microgram/ml in 50% rabbit serum. cross-rea ... | 1978 | 79624 |
| diisopropylfluorophosphate-evoked inhibition of anaphylactic histamine release from human skin: decrease of the inhibition by storing the skin specimens. | antigen-induced histamine release from human skin slices passively sensitized with reaginic serum in vitro was inhibited by dfp, suggesting involvement of serine esterase activation in the reaction. the magnitude of dfp-evoked inhibition of the histamine release was not the same in each skin sample and no correlationship was observed between the magnitude of the dfp-evoked inhibition of the histamine release and that of the histamine release in the absence of dfp. the magnitude of the histamine ... | 1979 | 84487 |
| fimbriae of actinomyces viscosus t14v: their relationship to the virulence-associated antigen and to coaggregation with streptococcus sanguis 34. | 1) fimbriae from a. viscosus t14v may be similar to those found on other bacteria. 2) the antigenic difference between virulent and avirulent a. viscosus t14 appears to be of a quantitative rather than a qualitative nature and is related to fimbriae and not to the cell wall polysaccharide. 3) coaggregation between a. viscosus t14v and s. sanguis 34 is mediated by fimbriae on the former which have specificity for beta-linked galactosyl residues. | 1978 | 84522 |
| [syncope and transitory amaurosis during mastocytosis]. | in a 70-year old man who has been suffering for 20 years from mastocytosis, a syncope followed by a transitory amaurosis occured. neurological complications of mastocytosis are exceptionnal. syncope is the most frequent, secondary to a drop in arterial pressure due to an inappropriate discharge of histamin. | 1978 | 84544 |
| [effect of s-adenosyl-l-methionine on the cerebral and peripheral metabolism of l-dopa]. | the repartition of [3h]l-dopa administered i.p. does not change in rats treated with s-adenosyl-l-methionine (sam). the effect was studied on the central nervous system and at the periphery. the biosynthesis of metabolites [3h]dopamine and [3h]3-o-methyldopamine are also unchanged. on the other hand, in the kidney an accumulation of [3h]norepinephrine +[3h]normetanephrine was observed, while in the brainstem + midbrain the synthesis of these metabolites was decreased after sam injection. the rel ... | 1978 | 84550 |
| study of the glycolipid composition of the milk fat-globule membrane and the mouse mammary tumour virus prepared from the milk of infected swiss mice [proceedings]. | | 1978 | 84579 |
| effect of trypsin and chymotrypsin on the polypeptides of large and small plaque variants of foot-and-mouth disease virus: relationship to specific antigenicity and infectivity. | large and small plaque variants of a12 foot-and-mouth disease virus were shown to have specific antigenic determinants. large plaque virus antigenic specificity was destroyed by trypsin treatment, but the small plaque antigen was resistant despite cleavage of the trypsin-sensitive polypeptide. the cleavage of polypeptide vp3 by trypsin resulted in the formation of a new antigen not present on untreated virus. the effects of chymotrypsin and trypsin on the polypeptides of the plaque variants have ... | 1978 | 84854 |
| [determination of protein-sh groups with ddd reagent]. | | 1976 | 85309 |
| streptococcal pharyngitis: diagnosis by gram stain. | group a beta-hemolytic streptococci were isolated from 49 (10.4%) of 472 patients with pharyngitis. throat culture results, interpreted by five observers of varying experience, showed the mean sensitivity, specificity, and predictive value of a positive gram-stained smear of pharyngeal secretions as 73%, 96%, and 71%. assignment to a high-risk group by clinical algorithm gave sensitivity, specificity, and predictive value of only 45%, 83%, and 23%. the gram-stained smear is the most accurate met ... | 1979 | 85421 |
| subarachnoid space of the cns, nasal mucosa, and lymphatic system. | we have briefly reviewed the literature pertaining to the movement of tracer molecules and infectious organisms within the olfactory nerve. there is a body of evidence indicating that tracers placed in the csf will quickly move via the olfactory nerve to the nasal mucosa and then to the cervical lymph nodes. organic and inorganic tracer materials and organisms as diverse as viruses, a bacillus, and an amoeba, when placed in the nasal cavity, have been shown to move from the nasal mucosa via the ... | 1979 | 85446 |
| dorsal column nuclei and ascending spinal afferents in macaques. | cell populations and thalamic projections of the dorsal column nuclei in macaques have been investigated in the medullae of normal animals and of animals with injections of horseradish peroxidase in the nucleus ventralis posterolateralis. in the same species, the course, distribution and origin of ascending non-primary pathways to the dorsal column nuclei have been demonstrated with the aid of degeneration methods, 3h-amino acid autoradiography and retrograde axonal transport of horseradish pero ... | 1979 | 85470 |
| responses of lateral preoptic neurons in the rat to hypertonic sucrose and nacl. | multiple-unit recordings were taken from the lateral preoptic region during a series of hypertonic and isotonic nacl and sucrose intracarotid injections. subjects were 11 hooded rats (8 males and 3 ovariectomized females) under urethane anesthesia. the data showed that under favorable cannulation conditions there were strong multiple-unit responses to hypertonic sucrose injections, and that under these conditions nacl injections were not significantly more effective than sucrose injections. the ... | 1979 | 85536 |
| relationship of intracellular 3',5'-adenosine monophosphate accumulation to parathyroid hormone release from dispersed bovine parathyroid cells. | | 1978 | 85548 |
| [perichordal necroses. contribution to the understanding of the spinal column morphogenesis]. | in 12--15 days old rat embryos and 12 days old mouse embryos vitally stained by acridin orange, a perichordal necrosis appears, showing metameric intensifications at the level of the dense sclerotomites. similar aspects were detected in serially sectioned rabbit and human embryos (6--7 mm c.r. length). the authors correlate the necrotic zones mentioned with the inductive functions of the notochord. | 1978 | 86154 |
| [intratypical antigenic differentiation of poliovirus strains circulating in mali by means of cross-adsorbed sera]. | the intratypic antigenic differentiation of poliovirus strains isolated from sick or healthy children in mali in 1975-1976 was performed. the method is based on the use of cross-adsorbed sera in the neutralization tests in which the virus is titrated by the plaque procedure or by the cytopathic effect. all the examined strains of serologic types i, ii, and iii were distinguished by the antigenic structure from the vaccine strains and were classified as "wild". quantitative differences in the ant ... | 1978 | 86237 |
| the role of lysine in the serological specificity of some proteus mirabilis lipopolysaccharides. | | 1978 | 86335 |
| the isolated human cortex. a golgi analysis of krabbe's disease. | the clinical course of a child with krabbe's leukodystrophy was characterized by clinical seizures, startle myoclonus, and paroxysmal activity recorded by eeg. at autopsy in the fourth year, myelinated subcortical axons were destroyed, virtually completely. despite isolation from major subcortical and interhemispheric connections, the cell and fiber pattern of the cortex appeared remarkably normal in routine histologic preparations. the normal range of pyramidal and stellate interneurons were al ... | 1979 | 86346 |
| inhibition of neuronal firing by opiates: evidence against the involvement of cyclic nucleotides. | 1. extracellular recordings were made in vitro from single neurones of the myenteric plexus of the guinea-pig ileum. 2. neuronal firing was inhibited by morphine and normorphine (10 nm to 1 micrometer). cyclic adenosine 3',5'-monophosphate (cyclic amp) (100 micrometer to 1 mm) also inhibited the firing of the majority of the neurones. prostaglandin e2 usually caused a short-lasting excitation of myenteric neurones and the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine was usually withou ... | 1979 | 86371 |
| free amino acids and ninhydrin-reacting compounds of median and lateral lobes in human benign prostatic hypertrophy. | the levels of free amino acids and ninhydrin-reacting substances were determined in median and lateral lobes of human benign prostatic hypertrophy. student's paired t test showed only a statistical difference for the hypotaurine concentration. this compound is present at higher levels in the lateral lobes. the different hypotheses formulated in the literature about the presence and possible metabolic role of hypotaurine in the male reproductive tract are examined. | 1979 | 86445 |
| effect of rabbit anti-human b-cell antigens on the response of lymphocytes stimulated by blastogenic factor. | it has been shown that specific antisera to b-cell determinants can block stimulation in the human mixed lymphocyte reaction. therefore, it is of interest to study the effect of anti-human b-cell serum on blastogenic activities of the cell-free culture medium (cfm) derived from cultures of human blood lymphocytes. b-cell antigen was prepared from human b-cell line as a glycoprotein complex of mol. wt 27,000 and 33,000. rabbit antisera to the b-cell antigen after absorption with human platelets o ... | 1978 | 86505 |
| the phenomenon of differentiation in murine erythroleukemic cells. | | 1978 | 86529 |
| automatic cell identification and enrichment in lung cancer. i. light scatter and fluorescence parameters. | two physical parameters were investigated to automatically recognize cells in sputum from human squamous cell carcinoma of the lung and to separate them for preparation by the papanicolaou methods, for human interactive identification and for automated high resolution image analysis. the two parameters, 0.5-15.0 degrees forward argon-ion laser light scatter to estimate total cell size and 546 nm acridine orange fluorescence to approximate total cell dna content, were measured in a flow-through f ... | 1979 | 86575 |
| chronic relapsing experimental allergic encephalomyelitis. correlation of circulating lymphocyte fluctuations with disease activity in suppressed and unsuppressed animals. | groups of juvenile strain 13 guinea pigs sensitized for chronic relapsing experimental allergic encephalomyelitis (eae) with isogeneic central nervous system (cns) tissue in complete freund's adjuvant (cfa) were either left to develop late-onset chronic eae (unsuppressed), or given a series of injections of bovine myelin basic protein (mbp) in incomplete freund's adjuvant (ifa) to suppress the disease. all unsuppressed animals developed disease and all suppressed animals remained healthy over a ... | 1979 | 86602 |
| klebsiella and ankylosing spondylitis--molecular mimicry? | | 1979 | 86725 |
| vidarabine monophosphate in viral encephalitis. | | 1979 | 86765 |
| definition of two ld antigens in rhesus monkeys. | two rhesus (macaca mulatta) monkey lymphocyte-defined (ld) antigens have been identified using two typing cells as stiumlators in a one-way mixed leukocyte culture (mlc) assay. an analysis of the genetic behavior of these ld antigens in six rhesus monkey families revealed that both antigens were linked with rhla. one probable recombinant indicated that the ld locus lies outside the two known rhla-sd loci and the locus which controls the serum protein, properdin b(bf). these two antigens, ld1 and ... | 1979 | 87026 |
| study on dissimilatory reduction of sulphates. | a new strain of sulphate reducing bacteria was isolated from swampy forest soil. after 120 h reduction, sulphate conversion attained 100%, the molar ratio of the consumed lactate and reduced sulphate amounted to 2:1. this confirms the reduction mechanism proposed by senez (1951). | 1979 | 87119 |
| similarity of casein- and endotoxin-induced, myeloma- associated and aged sjl/j amyloid in various strains of mice. | amyloidosis was induced in a number of strains of mice by repeated injections of casein and endotoxin. spontaneous amyloid was obtained from balb/c mice bearing a myeloma tumor (igg2a producing mopc 173 tumor) and from aged sjl/j mice. both the induced and spontaneous forms were similar in their size, immunological reactivity, peptide maps and in the susceptibility of histological sections to oxidizing agents with or without trypsin digestion. since case-induced murine amyloid resembles the noni ... | 1979 | 87374 |
| the expression of ia antigenic determinants on macrophages required for the in vitro antibody response. | a subpopulation of antigen-presenting macrophages required for an in vitro antibody response to burro erythrocytes was deleted by pretreating the splenic macrophages with anti-ia serum and complement (c). the in vitro response of the macrophage depleted t-b cell population could not be restored by the addition of macrophages resistant to anti-ia antibodies and c (ia-). the response of ia- macrophages and the macrophage-depleted t-b cells was only reconstituted by the addition of ia+ macrophages. ... | 1979 | 87431 |
| immune suppression in vivo with antigen-modified syngeneic cells. ii. t cell-mediated nonresponsiveness to fowl gamma-globulin. | intravenous administration of syngeneic spleen cells coupled with the palmitoyl derivative of fowl gammma-globulin (p-f gamma g) results in a profound state of f gamma g-specific tolerance in c57bl/6 mice. administration of p-f gamma g coupled syngeneic cells specifically reduces both the primary and secondary hapten and carrier-specific pfc responses to tnp-f gamma g. since the haptenic response is affected, the tolerance functions at the level of the f gamma g-specific helper t cell. as few as ... | 1979 | 87447 |
| reticuloendotheliosis virus: detection of immunological relationship to mammalian type c retroviruses. | reticuloendotheliosis virus (rev) p30 shares cross-reactive determinants and a common nh2-terminal tripeptide with mammalian type c viral p30's. an interspecies competition radioimmunoassay was developed, using iodinated rev p30 and a broadly reactive antiserum to mammalian virus p30's. the avian leukosis-sarcoma viruses and mammalian non-type c retroviruses did not compete in this assay. previous data indicating that the rev group is not represented completely in normal avian cell dna lead us t ... | 1979 | 87519 |
| limited immunodeficiency. | | 1978 | 87559 |
| effect of rubella vaccination programme on serological status of young adults in united kingdom. | antibody to rubella virus was measured in over 10,000 serum samples collected in 1976, 1977, and 1978 from young adult blood donors and university students. the incidence of seronegatives was lower (4--7%) among females born in 1956 and subsequently--i.e., among the age groups offered rubella vaccine at school--than among females born before 1654 (11--20%). the incidence of seronegatives among males in the 1977 and 1978 surveys had the opposite trend, with a higher proportion of seronegatives in ... | 1979 | 87687 |
| cefotaxime for bacterial meningitis. | | 1979 | 87714 |
| human breast carcinoma antigen is immunologically related to the polypeptide of the group-specific glycoprotein of mouse mammary tumor virus. | we have shown [mesa-tejada, r., keydar, i., ramanarayanan, m., ohno, t., fenoglio, c. & spiegelman, s. (1978) proc. natl. acad. sci. usa 75, 1529--1533] that an antigen immunologically related to gp52, a 52,000-dalton glycoprotein of the mouse mammary tumor virus, can be identified in sections of human breast cancer by means of an indirect immunoperoxidase technique. the specificity of the reaction was established by absorption experiments which revealed that only purified gp52, or material cont ... | 1979 | 88056 |
| characterization of an amphotropic murine c-type virus that is nb-tropic. | | 1979 | 88128 |
| binding of antigen to surface ig during in vitro hyposensitization of isolated rat mast cells. | the mechanism of in vitro hyposensitization was examined in isolated rat mast cells. surface distribution of immunoglobulin was examined by immunofluorescence technique. hyposensitization could be ascribed neither to changes in the distribution of surface immunoglobulins nor to capping or shedding phenomena. the distribution of cell-bound antigen and the number of antigen-positive cells (patch-bearing cells) was not changed by hyposensitization. the binding of antigen to surface ig was quantitat ... | 1979 | 88188 |
| denaturization of allergen p: effect on allergenicity, antigenicity and immunogenicity. | when allergen p was denatured by 8m urea, the modified molecule still reacted with ige specific for the native allergen but not with hemagglutinating antibodies. heating at 100 degrees c abolished the reaction in both cases. the results suggested differences between allergenic and antigenic capacities which may be based on structural differences of the antigenic determinants. | 1979 | 88195 |
| [simple method of detection of fc receptor sites on cells]. | a bacterial adhesion technique for identification of fc-receptor bearing cells is based on the ability of staphylococcus aureus, cowan 1 strain, to form rosettes with cells previously treated with immune complexes or heat aggregated ig g. the new technique is distinguished from other fc-receptor detection methods by its simplicity and ease of detection of both immune complexes and aggregated igg-binding cells. | 1979 | 88236 |
| occurrence of a thermostable antigen of ovarian carcinoma in normal tissues and secretions. | thermostable antigen (ta) occurs in ovarian carcinoma and in certain specialized tissues. high titers of ta were found in nineteen of twenty endocervical extracts but not in myometrium, endometrium, or exocervix. ta was present in all of sixteen cervical mucus samples. antibodies to perchloric acid extract of bronchus showed cross-reaticity with ta from ovarian carcinoma and cervix. immunofluorescence with frozen sections revealed ta to be present in the columnar epithelium of ovarian neoplasms, ... | 1979 | 88253 |
| surface antigens of human glioma cells shared with normal adult and fetal brain. | | 1979 | 88260 |
| 4th international workshop on human gene mapping. report of the committee on the genetic constitution of the x and y chromosomes. | | 1978 | 88299 |
| the h-y antigen:production of antibodies, detection, and cross-reaction between mouse, rat, and human. | | 1978 | 88303 |
| t antigen banding on chromosomes of simian virus 40 infected muntjac cells. | chromosomes were prepared from mitotic munjac cells 48 to 72 h after infection with sv40 virus. when stained for sv40 t antigen by indirect immunofluorescence, all chromosomes within an infected cell were fluorescent, indicating the presence of t antigen. furthermore, the chromosomes were not uniformly stained but appeared to have regions of high and low fluorescence intensity. a variety of controls showed that the banding patterns are specific and highly reproducible and may indeed reflect the ... | 1979 | 88306 |
| changes in seizure susceptibility, sleep time and sleep spindles following thalamic and cerebellar lesions. | the present experiment attempted to clarify conflicting evidence on the relationship of sleep spindles to seizure activation. seizure thresholds were calculated in minutes post-injection following ip administration of the convulsant drug monomethylhydrazine (mmh) to cats with lesions intended to alter the occurrence of spontaneous 12-15 c/sec sleep spindles recorded from sensorimotor cortex. twelve cats with bilateral cortical and subcortical recording electrodes were divided into 3 groups recei ... | 1979 | 88323 |
| vestibulo-ocular responses during the states of sleep in the cat. | the vestibulo-ocular response (vor) was recorded during natural sleep in cats with chronically implanted electrodes. by using a small amplitude sinusoidal head rotation (11 degrees) peak-to-peak at 0.4 hz) which elicited only slow compensatory eye movements, the vor amplitude was found to decrease steeply (down to 40% or less) during slow-wave sleep. the phase of the vor with respect to head position remained approximately constant. with a larger amplitude of sinusoidal rotation (320 degrees pea ... | 1979 | 88340 |
| relative effectiveness of spinal cord and purified myelin basic protein in producing resistance to experimental allergic encephalomyelitis. | isolated myelin basic protein (mbp) was less effective than an equivalent amount of spinal cord in inducing protection against experimental allergic encephalomyelitis produced by a challenge of either cord, purified myelin or mbp. complete protection was only obtained when an mbp challenge was preceded by spinal cord treatment. there was a 100% incidence of disease in the guinea pigs pretreated with mbp before challenge with spinal cord or myelin, but the onset was delayed by 3--4 weeks and the ... | 1979 | 88369 |
| leishmania mexicana and leishmania tropica: cross immunity in c57bl/6 mice. | | 1979 | 88370 |
| termination of natural tolerance to alpha-foetoprotein in rats: study of cell-mediated immunity in the macrophage migration inhibition test. | immunization of rats with mouse alpha-foetoprotein has been earlier shown to induce the antibody response to self afp or rats. in this work a single injection of afpm resulted in termination of natural tolerance of effector t-cells to afpr, as shown by the macrophage migration inhibition test using peritoneal exudate cells from immunized animals. a significant reaction was elicited by both afpm and afpr in the course of primary, secondary and third immunization with afpm. pronounced mmi reaction ... | 1979 | 88377 |
| cytochemical analysis on a case of familial 17ps. | chromosome 17ps was identified in the mother and daughter but not the father of a normal family with no history of congenital abnormality. in addition to g-band and ag-nor staining, previously used to study this abnormality, we applied n-band and c-band techniques. our results showed that 17ps has no demonstrable ribosomal cistron or constitutive heterochromatin. | 1979 | 88409 |
| localization of the nucleolar organizer by computer-aided analysis of a variant no. 21 in a human isolate. | a variant chromosome no. 21 consisting of two stalks and two satellites in tandem was detected during a survey of a human isolate. the variant segregated in three generations of a large kindred. one male had the variant no. 21, a metacentric y, and a 47,xxy complement; however, no other evidence of chromosomal nondisjunction was found. computer-aided analysis of sequentially stained variant no. 21 chromosomes indicated that silver-stained material corresponded to the proximal stalk region (as de ... | 1979 | 88411 |
| antigenic determinants of influenza virus hemagglutinin. iii. competitive binding of antibodies directed against "common" and "strain-specific" antigenic determinants of a/memphis/72 hemagglutinin. | | 1979 | 88484 |
| release of prolactin and lh and histamine-containing cells in brain. | the effects of histamine released from mast cells by the compound 48/80, a degranulating agent, on plasma prolactin and lh levels, were examined in rats. compound 48/80 given systemically (s.c.) at a dose of 2 mg/100 g b.w. significantly increased at 15 and 60 min after injection, both prolactin and lh release in ovariectomized, steroid-primed rats. prolactin but not lh was also augmented in the plasma of male rats following s.c. administration of compound 48/80. there were no modifications of p ... | 1979 | 88502 |
| oncofetal antigen: a tumor-associated fetal antigen immunogenic in man. | oncofetal antigen (ofa) has been defined with the use of human natural antibodies as a membrane antigen of human cancer cells that cross-reacts with human fetal brain tissues. the immunogen that elicits the antibody is unknown. the present study was undertaken to examine the immunogenicity of the ofa found on tumor cells. postoperative melanoma patients were immunized with ofa-positive melanoma cells. anti-ofa reactivities in the immunized sera were titrated by the immune adherence assay with th ... | 1979 | 88539 |
| passive transfer in diabetes mellitus. | | 1979 | 88629 |
| [immunosuppression (author's transl)]. | among different procedures of immunosuppression in man medical treatment with cytotoxic drugs has become the most important. biological methods are still under development but promise to gain in importance since they are more specific and have fewer side effects. the clinical effect of immunosuppressive therapy in organ transplantation is undisputed. its effects has been proven in some but not all immuno-inflammatory diseases. before immunosuppressive therapy is started it must be known whether ... | 1979 | 88671 |
| the antiherpesvirus action of phosphonoacetate. | | 1979 | 88744 |
| the pathophysiology of asthma. | because postmortem studies of humans provide little information on the initial pathophysiologic events in asthma, animal models have been developed. recently the ascaris-allergic rhesus monkey has provided an opportunity to examine the onset of pathophysiologic changes following challenge and to correlate them with airway structure. these studies have suggested that the initial interaction between antigen and mast cells may occur in the bronchial lumen or in the epithelium superficial to the tig ... | 1979 | 89006 |
| mac-1: a macrophage differentiation antigen identified by monoclonal antibody. | | 1979 | 89034 |
| the effect of light chain gene expression on the inheritance of an idiotype associated with primary anti-(4-hydroxy-3-nitrophenyl)acetyl(np) antibodies. | | 1979 | 89036 |
| descending tracts of the lateral columns of the rat spinal cord: a study using the horseradish peroxidase and silver impregnation techniques. | the location of the cells of origin and the projection areas of descending fibre tracts of the spinal cord lateral columns were examined in rats. unilateral micro-transections of subpopulations of lateral column fibres, at c2 or t10, with subsequent application of horseradish peroxidase to the severed axons, allowed identification, by retrograde labelling, of those cell groups projecting to the spinal cord through the lateral columns. additionally, the pattern of fibre and preterminal degenerati ... | 1979 | 89111 |
| preparative isolation of the cell receptor for immunoglobulin e. | | 1979 | 89114 |
| clinical aspects of alpha 1-fetoprotein determination in human liver cancer and in humans and experimental animals at carcinogenic risk. | recent findings concerning the significance of alpha 1-fetoprotein (afp) as a tool for clinical diagnosis and monitoring of tumor diseases are reviewed briefly. the applicability of this protein marker to the early diagnosis of patients at carcinogenic risk is discussed. in addition, experimental data obtained with a model of chemical hepatocarcinogenesis are reported. the increase of proliferative activity in precancerous liver tissue preceded afp production under experimental conditions with a ... | 1979 | 89199 |
| antigenic analysis of human heart tissue--characterization of cardiac antigens. | the human heart antigens demonstrated in citric acid extracts by immunodiffusion were submitted to further analysis. heart antigens were precipitated at 30% to 70% saturated ammonium sulphate. these fractions contained antigens reactive with rabbit antisera to human heart. the third fraction out of four proteins which were separated by sephadex g-150 gel filtration, was reactive against rabbit antisera to human heart. the intensely stained proteins of both heart antigens were located at the nine ... | 1979 | 89208 |
| antigen-antibody system associated with non-a, non-b hepatitis detected by indirect immunofluorescence. | ten chimpanzees were infected with non-a, non-b hepatitis by inoculation of patient serum or serum from a chimpanzee previously inoculated with patient serum. convalescent serum from one of them reacted, in indirect immunofluorescent tests, with some of the hepatocyte nuclei in sections of autologous liver biopsy specimens and specimens from eight of the other chimpanzees. serum from a convalescent patient reacted in the same way. these positive sera did not react with liver sections from uninfe ... | 1979 | 89332 |
| changing pattern of schistosomiasis in egypt 1935--79. | a village in the nile surveyed for schistosomiasis by j. a. scott in 1935 was surveyed again in 1979. the same number of people as in the 1935 survey were randomly selected for investigation by the same parasitological techniques as those used by scott. the prevalence of schistosoma mansoni infection had increased from 3.2% to 73%, whereas s. haematobium infection, which had been very common in 1935 (74%), had almost disappeared (2.2%). in the local district hospital since 1972 the percentage of ... | 1979 | 89343 |
| prospective study of chlamydial infection in neonates. | chlamydia trachomatis was recovered from the cervices of 4% (36/900) of pregnant women tested. 20 infants born through chlamydia-infected cervices were followed up for a year, as were 18 infants born to chlamydia-negative mothers. a statistically significant excess of conjunctivitis and pneumonia was found in infants exposed to chlamydia. the attack-rate for inclusion conjunctivitis was 35% (7/20) and for chlamydial pneumonia it was 20% (4/20). chlamydiae were recovered from 10 of the 20 (50%) e ... | 1979 | 89446 |
| simulation and prevention of retrovirus--specific reactions by mycoplasmas. | from human mycosis fungoides tumor-derived cell lines, mycoplasma hyorhinis was isolated. this mycoplasma shared the following characteristics with retroviruses: uptake of 3h-uridine, but not of 3h-thymidine in cell culture; banding at 1.16 g/ml sucrose density and partial shift to retrovirus core density position (approximately equal to 1.24 g/ml) after detergent treatment; incorporation of 3h-tmp into high molecular weight material in standard reverse transcriptase assays with the template-pri ... | 1979 | 89623 |
| definition of lymphocyte antigens in rats: rt-ly-1, rt-ly-2, and a new mhc-linked antigen system. | | 1979 | 89738 |
| unilateral mixed lymphocyte reactivity in the rat. | | 1979 | 89740 |
| the development of our present views on the molecular aspects of human blood group specificity. | | 1979 | 89773 |