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purity and antigenicity of insulin preparations. 197798958
[association between hsv 2 antigen and colpocytologic finding (author's transl)].prophylactic gynecologic examinations were performed in 1440 women using colposcopy and vaginalcytology. a search for hsv antigen in cervical cells was performed hsv antigen was found in 12% of pap i--ii smears, in 41% of pap iii smears and in all cases of pap iv--v. it is suggested that there is a probable association between hsv 2 and cervical cancer.1977201227
isoenzymes of lactate dehydrogenase, acid phosphatase, alkaline phosphatase and peroxidase in monkey kidney cell cultures inoculated with herpes virus type 1.the variation of lactate dehydrogenase, peroxidase, acid and alkaline phosphatase isoenzymes was studied in vero cells inoculated with infectant and uv-inactivated herpes simplex virus type 1 (hsv--1). infectant hsv--1 induced quantitative and qualitative modifications in isoenzyme patterns within the first 4 hours post inoculation (p.i.). the modifications caused by the uv-inactivated hsv--1 were similar, but appeared 8 hours p.i. the possibility of using isoenzyme modifications as rapid, sensi ...1978209614
man, medicine, and machines. 1977406501
technic for serial bone sampling in canine skeletal labeling studies.a technic was described for repetitive bone sampling in beagle dogs. the procedure has provided ideal samples for quantitative histologic technics following 135 biopsies.19751091776
synthesis and secretion of hirudin by streptomyces lividans.to examine the secretory production of heterologous proteins by streptomyces lividans, we fused the dna encoding the signal peptide of the alpha-amylase inhibitor tendamistat, derived from s. tendae with a synthetic gene encoding the thrombin inhibitor hirudin. the analysis of secretion by immunoblots revealed an efficient translocation of hirudin through the membrane, with no detectable immunoreaction among the cellular proteins. the secreted hirudin was stable in the shaking culture for about ...19901367034
fpl 62064, a topically active 5-lipoxygenase/cyclooxygenase inhibitor.flp 62064 [n-(4-methoxyphenyl)-1-phenyl-1h-pyrazole-3-amine] is a dual inhibitor of prostaglandin synthetase and 5-lipoxygenase. the compound had anti-inflammatory activity in vivo in a number of models. it inhibited peritoneal inflammation induced by immune-complex when given locally. when applied to the skin, fpl 62064 inhibited uv irradiation-induced erythema and pge2 formation in the guinea pig and also oedema formation and eicosanoid production in the mouse ear produced by arachidonic acid. ...19902117338
patch clamp characterization of sodium channels expressed from rat brain cdna.sodium currents, ina, were recorded from xenopus laevis oocytes which had been injected with mrna synthesized by in vitro transcription of the rat brain sodium channel ii cdna (noda et al. 1986 a, b). patch pipettes were used to apply depolarizing voltage steps and to record macroscopic sodium currents of between 50 and 750 pa from cell-attached patches of the oocyte membrane. with a combination of whole-cell and patch clamp recording, the properties of the implanted sodium channels could be stu ...19872435540
[quantitative estimation of synaptic acetylcholinesterase inhibition with galanthamine using parameters of miniature endplate currents].miniature end-plate currents (mepc) were recorded in voltage clamped muscle fibers of the rat diaphragm at different degrees of acetylcholinesterase (ache) inhibition with galanthamine. a model has been suggested connecting the increase in mepc amplitude with the concentration of a competitive reversible ache inhibitor. using the model suggested, the changes in the junctional ache activity inhibited with different concentrations of galanthamine were estimated. the calculated value of the inhibit ...19883390582
[epidemiological analysis of japanese encephalitis. statistics collected in miyagi prefecture in the last 5 years]. 19694390886
measurements on the interfacial areas of hydrocarbon in yeast fermentations and relationships to specific growth rates. 19725029880
structural and antigenic properties of carcinoembryonic antigen (cea). 199991097
[measurement of the anti-complementary activity of gamma-globulin preparations for intravenous administration]. 20124100946
unusually mild course of beta-glucuronidase deficiency in two brothers (mucopolysaccharidosis vii).two brothers with oligosymptomatic mucopolysaccharidosis vii were observed from age 11 8/12 to 16 years, and 15 1/2 to 19 years, respectively. asymptomatic thoracic kyphosis and mild scoliosis were the prominent clinical features. herniae, hepatosplenomegaly, corneal clouding and shortness of stature were absent. both had alder type granulations in polymorphonuclear leukocytes and to a lesser degree in monocytes. ultrastructural analysis of blood leukocytes revealed polymorphous inclusions of pr ...2000101485
[multiprogrammable single-chamber pacemakers]. 20144071816
naproxen prevention of heterotopic ossification after hip arthroplasty. a prospective control study of 55 patients.the effect of naproxen on heterotopic ossification after total hip replacement was studied in a randomized, double-blind trial. twenty-eight patients received 250 mg naproxen thrice daily for 4 weeks postoperatively starting on the morning of the operation while 27 control patients received a placebo. three months after the operation, 13 patients in the control group had heterotopic ossification compared with 4 patients in the group that received naproxen; and after 1 year, the figures were 15 a ...20071904183
[energy supply for conduction of rhythmic excitation in somatic nerve trunks]. 2003156652
[in memory of jirÅ• kruml, m.d., c.sc]. 20051104202
hla associations with chemically defined ragweed pollen components. 199993812
pittfalls in the diagnosis of endocrine exophthalmy. 20051242208
the carpal tunnel syndrome: part ii.the carpal tunnel syndrome is a compression of the median nerve within the carpal tunnel with very specific signs and symptoms. anatomical dissection of 156 wrists is presented and then the authors compare their findings with the findings of other investigators. the purpose of this article is not to present results but rather to discuss the anatomic entities involved with the syndrome and to present the open treatment modality.20061550309
coronary-care units stem mortality rates. 20154488944
[posterior urethral valves in newborns and infants. treatment and clinical course].severe forms of posterior urethral valve are essentially seen in neonates and infants. in 6 neonates under the age of 3 months, the predominant presenting features were a deterioration in the general status and renal failure. transurethral section of the valves, after urinary drainage for an average of one month, restored patency of the lower urinary tract in every case. all children have persistent renal failure, which is moderate or severe in 4 cases. in 6 infants between the ages of 3 and 11 ...20021302118
[anterior antehypaphyseal insufficiecency in the elderly].the authors report 4 personal cases, and analyse 18 cases of anterior pituitary insufficiency in the elderly found in the world literature. the initial symptoms are not specific and are difficult to interpret. they are frequently attributed to physiological ageing. in the absence of early diagnois, the patient may become comatose, this coma is often irreversible in spite of hormone treatment. in 60% of cases, the cause of the pituitary failure was not found. in the onset of the latter, the role ...2003166436
familial dupuytren's contracture with predominantly female expression.a family pedigree is described in which a strong dupuytren's trait is manifest predominantly on the female side. the genetic aspects of the condition are reviewed and the importance of gene penetrance is stressed.2004444771
familial cavernous malformations. diagnostic potential of magnetic resonance imaging.three patients from the same family underwent operations for neurological symptoms related to vascular lesions that proved on pathological examination to be cavernous malformations. two of the lesions were intracranial and one was in the thoracic spine. five other family members have also had neurological symptoms; three of these five were studied with cerebral magnetic resonance imaging and computed tomography. the vascular malformations seen on computed tomography scans were more clearly delin ...20123375976
the ninety-nine day kaiser. 20133549136
[changes of potassium, sodium, calcium and magnesium levels in patients with various forms of jaundice]. 20154755140
second conference on psychophysiological aspects of cancer. 20154390868
an improved method for the preparation of adnamine. 20154390843
measles in zaire: 1987.despite widespread efforts to prevent measles, a measles epidemic raged in zaire during 1986 and early 1987. hospitalized patients were studied with the goals of better understanding the weakness of the current efforts and of suggesting improvements in the local practice of primary health care. one hundred seventy five patients were hospitalized with measles or measles complications between october 1986 and february 1987 at the evangelical medical center in northeastern zaire. ten percent died. ...20123365904
[the behavior of basophilic granulocytes in obese children]. 19944167668
effects of probucol on hyperlipidemic patients with cardiac allografts.probucol, a well-tolerated new drug with moderate hypocholesterolemic effect in the general population, was evaluated in hypercholesterolemic (greater than 300 mg/dl) cardiac transplant recipients. nine patients received probucol, 500 mg twice daily, in a single-blind, placebo-controlled trial lasting 20 weeks. six patients responded with cholesterol falls of -20% (mean, -13.2%), and 1 patient showed minimal change. one patient developed cardiac rejection and was excluded, and another responded ...200094402
familial predisposition for otitis media in apache indians at canyon day, arizona.the familial occurrence of otitis media was studied in white mountain apache indians at canyon day, arizona. of the 760 residents, 366 persons were seen during a village survey for otitis media. there were 133 first-degree relatives involving 113 first-degree relative pairs. of these, there were 38 children involving 19 separate sibling pairs, for whom age- and sex-matched controls could be assigned. tympanic membrane scarring was assumed to be a marker of prior otitis media. the findings sugges ...20123569876
[why nursing and medical matériel?]. 20102814212
t cell specificity for class ii (i-a) and the encephalitogenic n-terminal epitope of the autoantigen myelin basic protein.the role of class ii restriction in t cell recognition of an epitope of the autoantigen myelin basic protein (mbp) has been investigated. encephalitogenic pl/j(h-2u) and (pl/j x sjl/j(h-2s))f1 ((plsj)f1) clones, isolated after immunization with intact mbp, recognize the n-terminal 11 amino acid residues of mbp in association with i-au class ii molecules. the synthetic peptide mbp 1-11 has been tested in vivo for induction of eae. clinical and histological eae occurs in pl/j and (plsj)f1 mice but ...20082440944
determination of potato glycoalkaloids and their aglycone in blood serum by high-performance liquid chromatography. application to pharmacokinetic studies in humans.the development of a high-performance liquid chromatography (hplc) method for the separation and quantification of potato glycoalkaloids and their aglycone solanidine in blood serum is reported. high selectivity was obtained by using solid-phase extraction followed by off-line dual-column hplc. injections were made via a sample enrichment column to achieve maximum sensitivity in the assay. the potato alkaloids in the hplc effluents were detected by ultraviolet absorption at 200 nm. the detection ...20051564109
cyclosporin a is effective, but not safe, in the management of behçet's disease. 20133707637
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