| stimulation of erythropoiesis in a grafted animal by mouse fetal liver culture media. | erythropoietin given to polycythemic, irradiated mice receiving a bone marrow transplant restores the number of erythroid colonies produced. in this study mouse fetal liver culture media administered to polycythemic, irradiated mice also restored the number of erythroid colonies and erythropoiesis as measured by 59fe incorporation. thus, mouse fetal liver in culture produces a factor which resembles erythropoietin. | 1977 | 321232 |
| the highest gene concentrations in the human genome are in telomeric bands of metaphase chromosomes. | chromosome in situ suppression hybridization has been carried out on human metaphase chromosomes to localize the g+c-richest human dna fraction (which only represents 3.5% of the genome), as isolated by preparative equilibrium centrifugation in cs2so4/3,6-bis(acetatomercurimethyl)-1,4-dioxane density gradient. this fraction essentially corresponds to isochore family h3. the rationale for carrying out this experiment is that this isochore family has, by far, the highest gene concentration, the hi ... | 1992 | 1594593 |
| purification and complex formation analysis of a cysteine proteinase inhibitor (cystatin) from seeds of wisteria floribunda. | seeds of wisteria floribunda contain several kinds of cysteine proteinase inhibitor (cystatin). we purified and characterized one of these inhibitors, named wcpi-3. the molecular weight of wcpi-3 was estimated to be 17,500 and 15,700 by gel filtration and sds-page, respectively. the isoelectric point was 5.7. wcpi-3 formed an equimolar complex with native papain and the dissociation constant was estimated to be 6.1 nm. complex formation between wcpi-3 and cys25-modified papain, such as s-carboxy ... | 1990 | 2292589 |
| heterologous signal peptide processing in fusion interferon synthesis by engineered l-forms of proteus mirabilis. | a recombinant dna proteus mirabilis l-form expression system, lvi (pjs127), was used to synthesize human fusion interferon alpha 1 (f-ifn-alpha 1). in the expression plasmid used, the complete coding sequence of ifn-alpha 1 was linked to the streptococcal spea promoter and the 5' end of the spea structural gene including its signal sequence coding region. lvi (pjs127) was capable of complete secretion into the culture medium of biologically active f-ifn-alpha 1 whose identity was confirmed by im ... | 1989 | 2661322 |
| [pulmonary surfactants in acute hypoxic hypoxia]. | | 1987 | 3609362 |
| biochemical and molecular epidemiology of human cancer risk. | | 1985 | 3903477 |
| the alpha-adrenoceptor blocking effect of indoramin on human isolated smooth muscle. | | 1973 | 4148431 |
| concerning the histamine receptor (h1). | | 1969 | 4390839 |
| the effect of mazindol on metabolic and regulatory changes in obese women during weight reduction. | the effect of mazindol (1 mg/day) on some metabolic and regulatory values was investigated in ten adult obese women and compared with the same number of controls during weight reduction in hospital (a five-times repeated cycle of 5 days complete starvation and 3 days on a 500 kcal(2.1mj/day diet.) mazindol caused a rise of hydroxyacyl coa dehydrogenase in striated muscle by 70 per cent and a marked decline in malic dehydrogenase. mazindol also produced higher levels of non-esterified fatty acids ... | 1999 | 93588 |
| osteomyelitis and arthritis caused by salmonella typhimurium in a crow. | salmonella typhimurium was isolated from an arthritic elbow joint of a crow (corvus brachyrhynchos) which also had bilateral osteomyelitis of proximal tibias. the prevalence of salmonella organisms in wild birds is reviewed briefly. | 1978 | 368353 |
| [delayed-action nicardipine in the prolonged treatment of chronic congestive heart failure in responsive subjects]. | we performed hemodynamic monitoring in 13 patients, 10 males and 3 females, mean age 57 +/- 11 years, affected by congestive heart failure, nyha class iii and iv. hemodynamic evaluation was made at basal condition and for 40 min after the administration of nicardipine (10 mg iv). we observed that in 3 patients cardiac index didn't rise (increase less than 15%) with clinical worsening during the monitoring (patients non responders), while in 10 patients cardiac index increased more than 15% (pati ... | 2008 | 2634478 |
| the taking of adequate cervical smears. | in order for cytological examination of a cervical smear to be an adequate method of screening for pre-invasive lesions, the smear must contain both squamous and endocervical cells. figures obtained for 1988 indicated that in south africa 45% of smears do not contain endocervical cells. the study reported, in which the same patients were compared in successive years but using different techniques, showed that with the use of biomedically designed tools 98.3% of smears can be classified as adequa ... | 2008 | 2315799 |
| data collection in the home health agencies of rhode island--home health agency management system brief. | | 2015 | 4496466 |
| congenital and perinatal sensory deprivation: some studies in early development. | | 2014 | 4101511 |
| [enzymes catalyzing the reduction of aldopentoses and the oxidation of pentitols in mycobacteria]. | m. phlei, grown on synthetic sauton medium (with 6% glycerol as carbon source), had nadph- and nadh-aldopentose reductase, as well as nad-pentitol dehydrogenase activities; some of their properties are studied. these activities are not present in bcg grown on the same medium. all experiments of aldopentose-reductase induction in bcg on a d(+)xylose medium were negative. | 1979 | 120778 |
| antibacterial efficacy of fabry's tinctura on the resident flora of the skin at the forehead. study of bacterial population dynamics in stratum corneum and infundibulum after single and repeated applications. | the in-vivo antibacterial activity of fabry's tinctura (ft), a 3 w% salicylic acid, 1 w% phenoli liquefacti containing 50 v/v% isopropanol used in dermatology for the treatment of erythrasma, pityriasis versicolor, acne vulgaris a.o. on the human resident skin flora was assessed by a new test method in comparison to 60 v/v% isopropanol. the test method consists of a detergent scrub method (dsm) in combination with the cyanoacrylate method (cam) thus allowing the quantitative determination of bac ... | 1986 | 3101321 |
| blockade of thromboxane and the prevention of eicosanoid-induced sudden death in mice. | we studied the effects of thromboxane-receptor antagonism and thromboxane synthetase inhibition in a thrombotic model of sudden death in mice. intravenous injection of arachidonic acid (aa; 80 mg/kg) or the prostaglandin-endoperoxide analog u-46,619 (2.3 mg/kg) results in sudden death in approximately 90% of the animals. pretreatment with the thromboxane receptor antagonist sq-29,548 (0.3-10 mg/kg) protects dose-dependently against aa and u-46,619-induced sudden death. in contrast, cgs-13,080, a ... | 1985 | 2996012 |
| selectivity of interferon action in simian virus 40-transformed cells superinfected with simian virus 40. | treatment of african green monkey kidney cv-1 cells with human alpha interferons before infection with simian virus 40 (sv40) inhibited the accumulation of sv40 mrnas and sv40 t-antigen (tag). this inhibition persisted as long as the interferons were present in the medium. sv40-transformed human sv80 cells and mouse sv3t3-38 cells express tag, and interferon treatment of these cells did not affect this expression. sv80 and sv3t3-38 cells which had been exposed to interferons were infected with a ... | 1985 | 2983099 |
| treatment and prophylaxis of pneumocystis carinii pneumonia. | | 1988 | 2976274 |
| initiation codons in mammalian mitochondria: differences in genetic code in the organelle. | the bovine mitochondrial gene products nd2 and nd4, components of nadh dehydrogenase, have been purified from a chloroform/methanol extract of mitochondrial membranes, and the human mitochondrial gene products nd2 and cytochrome b have been obtained by similar procedures. they have been identified by comparison of their amino-terminal protein sequences with those predicted from dna sequences of bovine and human mitochondrial dna. all of the proteins have methionine as their amino-terminal residu ... | 1987 | 2964865 |
| regulatory proteins of lobster striated muscle. | the regulatory proteins of lobster muscles consist of tropomyosin and of troponin. troponin contains a 17,000 chain weight component, two closely related components of about 30,000 and a 52,000 chain weight component. in addition to troponin, tropomyosin is required for the inhibition of the magnesium activated actomyosin atpase activity in the absence of calcium and for the reversal of this inhibition by calcium. lobster tropomyosin interacts with rabbit actin and lobster troponin interacts wit ... | 1975 | 123757 |
| [aplastic anemia treated by isogeneic or allogeneic bone marrow transplantation (author's transl)]. | | 2004 | 368376 |
| [subacute thyroiditis]. | | 2015 | 4456099 |
| "transient hypothyroidism" in premature infants. | | 1998 | 106100 |
| psychiatric case register conference, 1965. | | 2016 | 4958253 |
| [a uniform diploma at last!]. | | 2007 | 1853082 |
| adrenoceptors in the guinea pig's gallbladder. | | 1972 | 4538420 |
| anxiety: a behavioural legacy. | | 1972 | 4488086 |
| [change in the antigenic structure of streptomycin-resistant mutants of klebsiella ozaenae]. | | 1974 | 4465650 |
| [experimental myasthenia. histological examination of muscles in immunized rats]. | | 1974 | 4427708 |
| stimulation of ribonucleic acid polymerase activity in vitro by prostatic steroid-protein receptor complexes. | a system has been developed which allows the stimulation in vitro of prostatic rna polymerase by prostatic 5alpha-dihydrotestosterone-protein receptor complexes prepared from the tissues of castrated rats. the reconstitution in vitro of such a system necessitates the purification of several subcellular components. two 5alpha-dihydrotestosterone-receptor complexes are located in the prostatic soluble supernatant fraction, separable by selective ammonium sulphate fractionation, and one complex can ... | 1973 | 4360714 |
| the mystery of life. | | 1980 | 291644 |
| semi-micro xc cell assay technique for murine leukemia virus. | the xc cell assay employed in in vitro titration of murine leukemia viruses was modified for use as a semi-micro procedure. | 1972 | 4110428 |
| a note on the projection from the rostral thalamus to the visual hyperstriatum of the chicken (gallus gallus). | the rostral thalamo-hyperstriatal projection in young chicks was examined following large injections of wheat germ agglutin labelled with horseradish peroxidase (hrp-wga) into the hyperstriatum. retrograde labelling of thalamic neurons was present in the dorsolateral thalamus, rostrolateral part (dlalr) and dorsolateral thalamus, lateral part (dll). there was no evidence of a contralateral projection from the lateral anterior thalamic nucleus (la) to the posterior aspect of the visual hyperstria ... | 1986 | 3956634 |
| aortic dissection in a gorilla. | autopsy findings in a 39-year-old male gorilla included aortic dissection, internal rupture of the aortic arch with axial direction of the tear, external rupture of the ascending aorta, cardiac tamponade, myocardial hypertrophy, cystic and basophilic degeneration of the aortic media, marked obesity, severe degenerative joint disease, focal glomerulonephritis, and widespread hemosiderosis. | 1986 | 3746887 |
| thyroid hormone modulation of vip's induced salivary secretion in the submaxillary glands of rats. | the effect of changes in thyroid function upon vasoactive intestinal peptide (vip) induced secretion of saliva were studied in male wistar rats. hyperthyroidism was induced by the sc administration every 12 h of 10 micrograms/100 g bw of i-triiodothyronine; hypothyroidism was induced by surgical thyroidectomy 2 weeks before the experiments. preganglionar parasympathetic denervation was induced by sectioning the chorda tympani on the left side. the dose-response curves to increasing doses of vip ... | 1986 | 3700977 |
| rewarding and aversive effects of stimulant drugs in infant rats. | four experiments investigated the reinforcing effects of cocaine, amphetamine, and phenylpropanolamine using odor as the conditioned stimulus and infant rats as the subjects. at the age of 2 days the rats were injected with saline or with one of the three drugs and placed for 30 min in a plastic bag with almond-scented shavings. at the age of 18 days the rats were deprived of water for 12 hr and then given two tests that required different responses. in the consumption test they were given 30 mi ... | 1987 | 3575345 |
| adenomatous dysplasia of the equine allantois. | | 1988 | 3232311 |
| choline supplementation increases serum alkaline phosphatase activity in rats. | | 1988 | 3180475 |
| malpais spring virus: a new vesiculovirus from mosquitoes collected in new mexico and evidence of infected indigenous and exotic ungulates. | two virus isolates, 1 each from aedes campestris and psorophora signipennis mosquitoes collected in south central new mexico in august 1985, were shown by neutralization tests to be identical to each other, but not to any of more than 250 arthropod-borne and other viruses. electron microscopy of 1 isolate (85-488nm, chosen as the prototype) indicated that this strain shares morphologic characteristics with viruses of the family rhabdoviridae. indirect fluorescent antibody tests indicated that th ... | 1988 | 3061310 |
| [apollinaire bouchardat's advice to diabetics]. | | 2016 | 4949250 |
| a report on genetic registers. based on the report of the clinical genetics society working party. | | 1998 | 106123 |
| second conference on psychophysiological aspects of cancer. | | 2015 | 4390868 |
| an improved method for the preparation of adnamine. | | 2015 | 4390843 |
| intestinal fistula from a toothpick. | | 1980 | 440256 |
| [impaired response to adrenal suppression tests in epileptic patients in treatment with carbamazepine]. | | 2013 | 3561370 |
| [neurohormones of the sympathetic nervous system in myocardial infarct]. | | 2016 | 4838734 |
| estimation of peptidoglycan antibodies by an immunoperoxidase technique. | an immunoperoxidase technique developed for the detection and measurement of anti-peptidoglycan antibodies is described. the technique is based on the mancini single radial immunodiffusion test with the addition of a reaction step with peroxidase-labelled anti-immunoglobulins. the dark-brown colour produced by the enzyme and a h2o2-diaminobenzidine solution increased the sensitivity considerably. the test was found to be highly specific and valuable both for the screening of total amounts of ant ... | 2002 | 126551 |
| the secret of medical management. | a review of the research on group practices punctures the myth of physician autonomy in hospitals and opens the way for administrators to join in controlling the patient care process. | 2009 | 2670836 |
| [acute pain and practical nursing care. i]. | | 2009 | 2860729 |
| [innovation, pliers for removal of temporary crowns]. | | 1998 | 107008 |
| [determination of cardiac glycoside concentration in the serum]. | | 1998 | 124710 |
| unusual decor dispels tension. | | 2015 | 4500136 |
| task characteristics and a stage 6 sensorimotor problem. | a previously demonstrated high rate of failure on a stage 6 sensorimotor means-end problem, of children otherwise inferred to be in stage 6 development, prompted a study of task characteristics of the problem. a component part of the task was modified by introducing an additional visual cue; the purpose of the problem was unchanged. results indicated that problem solving was facilitated in the transformed condition, with older subjects performing somewhat better than younger subjects. the author ... | 2005 | 1183275 |
| [energy supply for conduction of rhythmic excitation in somatic nerve trunks]. | | 2003 | 156652 |
| glycogenosis with amylopectinoid deposits in a 13-year-old girl. | we present a clinical study and muscle biopsy of a 13-year-old female who suffered hypertrophic cardiomyopathy, hepatosplenomegaly and myopathy of prolonged evolution. the muscle biopsy showed a glycogenosis with deposits of amylopectin-like material. differential diagnosis was made with basophilic degeneration of the myocardium, and with "polyglucosan bodies disease." in the existing literature we found only one case of juvenile amylopectinosis, and another four adult cases. | 2011 | 3203479 |
| estimation of missing cone data in three-dimensional electron microscopy. | the range of tilt angles for which projected images of two-dimensionally periodic specimens can be obtained in electron microscopy is limited both by technical aspects, such as goniometer design, and by the more fundamental limitation of object thickness. the lack of a full set of projections causes a missing cone in the reciprocal space data for the object, which will give an anisotropic resolution in a three-dimensional reconstruction and may cause the quality to be impaired by spurious featur ... | 2011 | 3244969 |
| [occupational diseases associated with dental practice]. | | 2012 | 3482444 |
| [advances in the therapeutic approach to hypertension before the recent epidemiological and physiopathological verifications]. | | 2013 | 3813918 |
| antabuse contracts for married alcoholics and their spouses: a method to maintain antabuse ingestion and decrease conflict about drinking. | antabuse is widely used in alcoholism treatment as a deterrent to impulsive drinking when the alcoholic encounters some temporary life crisis or other stressful situation. unfortunately, antabuse therapy often is not effective because the alcoholic discontinues the drug prematurely. marital conflicts and arguments, frequently about past drinking or the likelihood of future drinking, are an important stressor that can lead the newly abstinent alcoholic to relapse. the antabuse contract procedure ... | 2013 | 3735473 |
| is there a surplus? | | 2013 | 3705402 |
| surveillance of 'at risk' elderly in the community. | | 2013 | 3634922 |
| gene-spliced hormone for growth approved. | | 2013 | 3901256 |
| the prognostic value of serum immunosuppressive effect in patients with ovarian cancer. | sixteen patients who underwent surgery and postoperative chemotherapy for carcinoma of the ovary were studied. eleven survived more than 18 months without evidence of recurrence, and 5 died more than 5 months after surgery. serial determinations were made preoperatively and postoperatively of the immunosuppressive effect of the serums of these patients on the response of normal lymphocytes to phytohemagglutinin stimulation. these determinations were plotted for each patient; the shapes of the cu ... | 1980 | 440651 |
| [functional disturbances of the masticatory organ as a new problem in social dentistry]. | | 1980 | 293774 |
| aniseikonia and stereoacuity in pseudophakic patients. unilateral and bilateral cases. | to evaluate the efficacy of intraocular lens (iol) implant procedures, analyzing visual function of the operated eyes and the resulting binocular vision. | 2006 | 1513582 |
| gaba triggers a cl- efflux from cultured glial cells. | | 2007 | 2816442 |
| [use of oral isotretinoin in the treatment of cutaneous lupus erythematosus]. | twenty-four in- or out-patients (12 males and 12 females) with chronic cutaneous (ccle) (n = 19) or subacute cutaneous (scle) (n = 5) lupus erythematosus have been treated with oral isotretinoin. the initial dose 0.15 mg/kg/day was progressively increased to a maximum of 0.50 mg/kg/day; the total treatment period was 16 weeks. one female patient with scle stopped the therapy for sudden fever. none of the other known side effects induced interruption of treatment. in 20 subjects (86.9%) isotretin ... | 2008 | 2630441 |
| [oculogyric crisis as an initial symptom of juvenile parkinsonism-like disease]. | a 12-year-old boy developed occasional attacks of oculogyric crisis after physical exercises or when tired. following the initial symptom, progressive parkinsonian features such as bradykinesia, muscular rigidity, hand tremors in posture, mild dysarthria and disorder of postural reflexes developed. there was no marked diurnal fluctuation o symptoms. serum ceruloplasmin, copper levels, cranial x-ray ct scan and mri were normal. measurement of the plasma levels of l-dopa after single oral administ ... | 2008 | 2605835 |
| a37812: n-methylstreptothricin f. | a37812, a new member of the streptothricin class of antibiotics, has been isolated and characterized as n-methylstreptothricin f. the structure elucidation of a37812 is based on results from 13c and 1h nmr spectroscopies. | 2009 | 2995294 |
| extramural cross-validation of the mayo primary biliary cirrhosis survival model establishes its generalizability. | the generalizability of the mayo model for predicting survival in individual primary biliary cirrhosis patients without liver transplantation was tested and confirmed. the model was applied to a data base of patients from the new england medical center hospitals (n = 141) and the scott and white clinic (n = 35) and found to predict their survival accurately. it was also shown to be accurate for mayo primary biliary cirrhosis patients with very advanced disease (n = 30), those with less than a 33 ... | 2009 | 2680867 |
| patchy retinal degeneration in tetraparental mice. | | 2014 | 4101137 |
| neurological consultation in the management of patients with systemic cancer admitted to a community hospital. | to characterize the neurological complications of cancer patients admitted to a community hospital, the charts of all cancer patients evaluated by a neurologist during a single year were reviewed. nine percent (n = 93) of cancer patients received neurological consultation compared to 3.6% of other patients. the neurologic problem preceded the diagnosis of cancer in 11% of patients. complications were most common with known metastases. neurologists frequently discovered signs not noted by the ref ... | 2011 | 3768759 |
| [circulating immunocomplexes in chronic hepatitis b]. | | 2014 | 4016846 |
| calcium channel blocking agents and the heart. | | 2014 | 3933699 |
| [clinical value of determining carbonic anhydrase activity and zinc in children with acute pneumonia]. | | 2015 | 4627488 |
| double-blind evaluation of verapamil, propranolol, and isosorbide dinitrate against a placebo in the treatment of angina pectoris. | in the treatment of angina pectoris a double-blind evaluation of verapamil (cordilox) at two dose levels-namely, 80 mg thrice daily and 120 mg thrice daily-propranolol (inderal) 100 mg thrice daily, and isosorbide dinitrate (vascardin) 20 mg thrice daily has been made against a placebo. the assessment was based on relief from daily attacks of angina on effort and the response to a whole-body exercise test. we can find no statistically significant difference between the effects of verapamil (120 ... | 2015 | 4570671 |
| [metampicillin in treatment of suppurative meningitis. apropos of 22 cases with 27 dosages of metampicillin in the c.s.f]. | | 2015 | 4460240 |
| treatment of bell's palsy. | | 2015 | 4330911 |
| [culture of lymphoid cells in immunological investigations]. | | 2016 | 4928839 |