| hco3- and h+ secretion in rat ileum in vivo. | replacing cl- in the perfusion fluids decreased the luminal ph of rat ileum perfused in vivo. varying the initial ph in cl- depletion studies indicated an equilibrium ph near 6.6. na+ depletion in cl- deleted fluids partially inhibited luminal acidification. addition of hco3- accelerated na+ absorption and decreased cl- absorption. luminal pco2 was increased using fluids buffered to initial ph 6.6, suggesting secretion of hco3- rather than oh-. the decreased hco3- secretion using cl- depleted fl ... | 1977 | 18015 |
| new procedure for the production of influenza virus-specific double-stranded dna's. | a novel technique is described for the production of pure, full-length influenza virus ds dna's corresponding to each segment of the influenza virus genome, and suitable for molecular cloning and restriction endonuclease mapping. the method involves the synthesis of dna complementary to both virion (negative strand) and messenger (positive strand) rna, gel purification and annealing. by avoiding the use of si nuclease, which often removes the terminal regions of dna duplexes, the method allows t ... | 1979 | 92012 |
| effect of secretin, glucagon and vasoactive intestinal peptide on the hormone-sensitive rat cardiac adenylate cyclase [proceedings]. | | 1979 | 93901 |
| changes in cardiac norepinephrine in spontaneously hypertensive and stroke-prone rats. | the norepinephrine (ne) concentration of cardiac ventricles was determined by radioenzymatic assay in normotensive wistar kyoto rats (wky), spontaneously hypertensive rats (shr), and stroke-prone rats (spr) at 3-6, 14-19, and over 31 weeks of age. there was no difference between strains prior to hypertension, but a progressive decrease in cardiac ne concentration occurred in shr and particularly in spr relative to wky after hypertension was established. this decrease was not due to cardiac hyper ... | 1979 | 94373 |
| [testing of a system of unidirectional serologic reactions for detection of diphtheria antigens and antibodies]. | | 1979 | 106599 |
| bronchus-associated lymphoid tissue (balt) in the laboratory-bred and wild rat, rattus norvegicus. | in juvenile wild rats, bronchus-associated lymphoid tissue (balt) development was similar to that seen in adult specified-pathogen-free rats. in adult wild rats the balt was widespread. in one animal infected with a mycoplasma-like organism, a region of bronchoepithelium overlying a large balt nodule was seen, through which lymphocytes appeared able to pass to make direct contact with the bronchial lumen: the significance of this observation is discussed. there was no evidence of infection in lu ... | 1979 | 162238 |
| characterization of simian cells tranformed by temperature-sensitive mutants of simian virus 40. | seven lines derived from primary african green monkey kidney cells, which had survived lytic infection by wild-type simian virus 40 (sv40) or temperature-sensitive mutants belonging to the a and b complementation groups, were established. these cultures synthesize sv40 tumor (t) antigen constitutively and have been passaged more than 60 times in vitro. the cells released small amounts of virus even at high passage levels but eventually became negative for the spontaneous release of virus. virus ... | 1976 | 178917 |
| age-dependent relaxation of gene repression: increase of endogenous murine leukemia virus-related and globin-related rna in brain and liver of mice. | a progressive loss in the ability of cells to maintain their normal specialized states of differentiation could be the common denominator underlying much of the physiology and pathology associated with the mammalian aging process. we investigated this possibility by searching for an age-dependent derepression of endogenous genes in tissues in which they are not normally expected to be expressed. complementary dna (cdna) probes to globin genes and to the murine leukemia type c rna virus (mulv) ge ... | 1978 | 212751 |
| nucleic acid and protein metabolism in the pancreas, spleen, thymus, lung, cardiac and skeletal muscle and lens of undernourished female rats. | | 1979 | 533871 |
| longitudinal effect of captopril on aortic and arteriolar development in normotensive rats. | to explore the effect of chronic converting enzyme inhibition on the macro- and microcirculation, normotensive rats were chronically given 100 mg/kg/day of captopril in their drinking water beginning one day before uninephrectomy. cremaster arteriolar dimensions were measured 2, 4, or 8 weeks later by intravital microscopy, before and after topical application of 10(-3) m adenosine. mean blood pressure were significantly decreased at 4 (17%) and 8 (18%) weeks in treated rats vs age-matched contr ... | 1992 | 1304458 |
| cytomegalovirus colitis in an older woman, successfully treated with ganciclovir. | cytomegalovirus (cmv) infections are usually found in immunocompromised persons and rarely present in those who are immunocompetent. we report a case of cmv colitis in an elderly woman presenting with delirium, prolonged fever, and diarrhea. treatment with ganciclovir, an antiviral agent, resulted in resolution of the colitis within 3 weeks without noticeable side effects. older adults may be more susceptible to cmv infection by virtue of age-related changes in immune function. the possibility o ... | 1992 | 1317403 |
| [postcoital uterine microbe colonization and endometritis in the mare]. | in the mare, natural breeding is associated with bacterial contamination of the reproductive tract. the purpose of this study was to examine postcoital bacterial contamination and the resulting inflammatory response of the uterus. uterine swabs for bacteriological and cytological examination were obtained from 80 mares. each mare was sampled once between 4 and 69 hours postbreeding. in mares which did not conceive, sampling was repeated at the following estrus. the findings were compared with th ... | 1991 | 1948985 |
| [allergy to insulin developed during exposure to human insulin]. | a case of allergy to human insulin is presented. the allergy developed during treatment with semisynthetic humanised insulin and was verified by a prick-test and rast analysis. | 1990 | 2238202 |
| subtype-specific increase in g-protein alpha-subunit mrna by interleukin 1 beta. | the guanine nucleotide regulatory proteins (g-proteins) which are substrates for adp-ribosylation by pertussis toxin (alpha i-1, alpha i-2, alpha i-3 and alpha o) transduce a variety of hormonal signals. endothelial cells express mrna for three alpha i subtypes although the level of alpha i-1 mrna is very low. interleukin 1 beta (il 1 beta), a pleiotropic inflammatory mediator which stimulates a complex series of responses in human endothelial cells leading to increased coagulation and platelet ... | 1989 | 2525485 |
| prevention of rectal cancer induced by n-nitrosobis(2-oxopropyl)-amine by exogenous testosterone in mrc rats. | rectal carcinogenicity of n-nitrosobis(2-oxopropyl)amine (bop) in male mrc wistar rats was shown to be inhibited by exogenous testosterone (t) when the hormone was given during, but not after, administration of the carcinogen. this effect was independent of the dose and frequency of bop, which was given either weekly for 20 weeks orally or daily for 3 days subcutaneously. since, except for prostatic cancer, the incidence and the patterns of other bop-induced tumors were not altered by t, this ho ... | 1989 | 2805225 |
| malpais spring virus: a new vesiculovirus from mosquitoes collected in new mexico and evidence of infected indigenous and exotic ungulates. | two virus isolates, 1 each from aedes campestris and psorophora signipennis mosquitoes collected in south central new mexico in august 1985, were shown by neutralization tests to be identical to each other, but not to any of more than 250 arthropod-borne and other viruses. electron microscopy of 1 isolate (85-488nm, chosen as the prototype) indicated that this strain shares morphologic characteristics with viruses of the family rhabdoviridae. indirect fluorescent antibody tests indicated that th ... | 1988 | 3061310 |
| a 'macro' image analysis of fura-2 fluorescence to visualize the distribution of functional glutamate receptor subtypes in hippocampal slices. | the distribution of functional glutamate receptor subtypes was visualized as regional changes in intracellular ca2+ concentration induced by administration of a specific agonist for each subtype. an image of the fura-2 fluorescence from a whole hippocampal slice was directly excited at 340 or 380 nm through an optical fibre and observed via a low-magnification objective lens (x4). a heterogeneous distribution of n-methyl-d-aspartate (nmda) and non-nmda subtypes was demonstrated by the ratio of f ... | 1991 | 1664923 |
| salmonella serotypes in india, 1982-83. | | 1988 | 3068130 |
| metabolism of hexachloro-1,3-butadiene in mice: in vivo and in vitro evidence for activation by glutathione conjugation. | 1. the metabolism of 14c-hexachloro-1,3-butadiene (hcbd) was studied in mice and in subcellular fractions from mouse liver and kidney. 2. in the presence of glutathione (gsh), liver microsomes and cytosol transformed hcbd to s-(pentachlorobutadienyl)glutathione (pcbg). pcbg formation in subcellular fractions from mouse kidney was very limited. oxidative metabolism of hcbd by cytochrome p-450 could not be demonstrated. 3. cysteine conjugate beta-lyase was present in mitochondria and cytosol from ... | 1988 | 3176519 |
| diagnosis of aelurostrongylus abstrusus and dirofilaria immitis infections in cats from a human shelter. | during a 6-month period, 108 sexually mature stray cats were euthanatized at a humane shelter in alabama. aelurostrongylus abstrusus was identified in 20 of the cats (18.5%) by baermann fecal examination, necropsy, or histologic examination. the baermann fecal examination was a more sensitive test for aelurostrongylosis than was necropsy or histologic examination. thoracic radiography was useful in identifying infected cats, but was a less sensitive and more nonspecific method of detection than ... | 1988 | 3366677 |
| the different effects of recombinant human tumor necrosis factor on rat fibrosarcoma sublines. | the antitumor effect of recombinant human tumor necrosis factor (rh-tnf) on two clones of rat fibrosarcoma with different metastatic potential to lymph nodes was examined. the colony formation of clone a, which has high metastatic potential, was completely inhibited by continuous exposure to rh-tnf at 50 u/ml. in contrast, colony formation of clone g, which has low metastatic potential, was not inhibited by high concentrations of rh-tnf (10,000 u/ml). the inhibitory effect of rh-tnf on colony fo ... | 1987 | 3594481 |
| unusual pharyngeal lesion causing dysphagia. | a 58-year-old man was evaluated for a 42-year complaint of a pharyngeal foreign body sensation whenever he ate. examination revealed normal anatomy at rest but diffuse hypopharyngeal distension with valsalva's maneuver. his past history was remarkable for an infectious illness, possibly diphtheria. we speculate that this unusual case most likely represents a postdiphtheritic selective pharyngeal paralysis and present his case, radiographic findings, and a discussion of the differential diagnosis ... | 1987 | 3674649 |
| lead toxicity in cats. | | 1992 | 1635502 |
| regional sensitivity of neuroleptic receptors to sub-acute soman intoxication. | sub-acute exposure to anti-cholinesterase organophosphorous compounds induces, in humans, cognitive and emotional deficits which include depression, anxiety, emotional lability, and schizophrenic-like symptoms. neuroleptic drugs used to treat similar clinical conditions bind to serotonergic (s2) and dopaminergic (d2) receptors, suggesting that these sites are involved in the psychiatric consequences of organophosphate exposure. rats were given saline or soman (50 micrograms/kg, sc) on a sub-acut ... | 1985 | 3995358 |
| [alcohol and endocrinologic homeostasis]. | in addition to direct toxic effects on endocrine organs chronic alcohol intake affects regulation of endocrine systems by disturbed liver function. as a result in patients with alcohol-induced liver cirrhosis gonadal axis is characterized by low total and free testosterone, elevated estradiol. lh, fsh, and sexual hormone binding globulin and an enhanced conversion of testosterone to estradiol. prolactin also is found to be elevated. the thyrotropic axis is characterised by low t3- und t4- as wel ... | 1988 | 3062942 |
| [comparative study of water, collagen and mucopolysaccharids contents in healthy human skin, in normal and keloid cicatrix]. | | 1970 | 4245538 |
| effects of in vivo and in vitro administered thyroxine on substrate metabolism of isolated rabbit ventricle mitochondria. 3. substrate effects on pyridine nucleotide reduction, on the reversal of electron transport, and on the "respiratory control by atp". | | 1971 | 4326787 |
| extraction of k + selective channels from excitable tissue. | | 1972 | 4338792 |
| [pyridazinilides (xiv). the action of p-phenyl-phenacyl bromide on 3-phenyl-pyridazine]. | this time the synthesis of some new derivatives obtained by the quaternary substitution of one of the heterocyclic nitrogen atoms and by reactions of dipolar cycloaddition is presented. the results of the tests on their antimicrobial and antiinflammatory actions are discussed. | 1989 | 2682894 |
| paired helical filaments from alzheimer disease patients contain cytoskeletal components. | neurofibrillary tangles from alzheimer disease patients share antigenic determinants with neurofilaments and microtubule-associated proteins, as shown by light microscopy immunocytology. the present study addresses the issue of whether these determinants are located on the paired helical filaments or on other components of the neurofibrillary tangle. sections from postmortem brains from alzheimer disease patients were stained by using bodian's silver method or immunostained by using poly- and mo ... | 1985 | 3889918 |
| [frequency and clinical importance of primary pharmacoresistance of mycobacteria in patients with tuberculosis of the lungs]. | | 1972 | 4626690 |
| [microassay of serum thyroxine with radioimmunological method]. | | 1972 | 4665425 |
| on the pharmacokinetics of the ethanol metabolite acetate: elimination from the blood and cerebrospinal fluid. | | 1973 | 4800451 |
| salmonellosis: an increasing health hazard. | | 1974 | 4825825 |
| topical indomethacin in extracapsular cataract surgery. a photographic study. | a photography-based single-blind study was conducted to evaluate the effect of topical indomethacin on the per-operative pupil of 52 consecutive patients undergoing an extracapsular cataract extraction with or without an intraocular lens. each operation was done by the author. per-operative miosis was significantly smaller in the group receiving indomethacin as compared with the control group (p = 0.06-0.13). a reproducible photographic method for evaluating the per-operative behavior of the pup ... | 2009 | 2669436 |
| [amyloidosis of the dialysis patient]. | | 2011 | 3077074 |
| pediatric radiation oncology--subspecialty training? | | 2006 | 1447024 |
| generic vs. branded carbamazepine. | | 2011 | 3200346 |
| tetrodotoxin, tarichatoxin, and chiriquitoxin: historical perspectives. | | 2012 | 3468842 |
| should doctors kill patients? | | 2012 | 3370567 |
| identification and characterization of deoxyguanosine-crotonaldehyde adducts. formation of 7,8 cyclic adducts and 1,n2,7,8 bis-cyclic adducts. | crotonaldehyde, a chemically reactive alpha,beta-unsaturated carbonyl compound, is an important industrial chemical and a ubiquitous environmental pollutant. it has been shown to be carcinogenic and mutagenic. we have studied the reaction of crotonaldehyde with nucleosides and 5'-mononucleotides and found three different types of adducts with deoxyguanosine and 2'-deoxyguanosine 5'-monophosphate. no adducts could be isolated either with nucleosides other than deoxyguanosine or with nucleotides o ... | 2006 | 1489932 |
| a simplified dissolution rate apparatus. | | 2015 | 4390845 |
| [morphological differentiation of neuroblastoma by 1 methyl cyclohexane carboxylic acid (cca) and some c1 derivatives]. | we describe the induction of neuroblastoma morphological differentiation by 1 methyl cyclohexane carboxylic acid (cca) and by some c1 derivatives of cca. this induction proceeds in a medium which allows, in the absence of inducer, a normal growth of neuroblastoma cells and contains 7.5% fetal calf serum. in order to establish a clear-dose response relationship and to compare the relative potencies of different drugs, the morphological changes were assessed by examining "long neurite-bearing cell ... | 2002 | 120786 |
| a new operation for insertion of the artificial urinary sphincter. | a new operation for implantation of the artificial urinary sphincter for total urinary incontinence in women is described. the procedure is done through the vestibule of the vagina with clear exposure of the vesical neck and urethra anteriorly, and easier accessibility for dissection of the vagina from the posterior wall of the vesical neck and upper urethra. this approach reduces the incidence of occlusive cuff erosion and eliminates the chance of shifting of the device. the model as 800 artifi ... | 2012 | 3411663 |
| a new technique of ankle arthrodesis. | a new technique of ankle arthrodesis is described and the results of 12 consecutive procedures are assessed. the method described employs three cannulated transfixion screws and an anterior approach to the ankle. eleven of the 12 ankles proceeded to solid fusion. one patient developed a painless fibrous non-union. there were no other significant complications. this simple technique provides good compression and adequate resistance to rotatory and angulatory stresses about the ankle fusion site. | 2006 | 1456908 |
| "transient hypothyroidism" in premature infants. | | 1998 | 106100 |
| dental care for seniors. | | 2011 | 3063356 |
| effects of probucol on hyperlipidemic patients with cardiac allografts. | probucol, a well-tolerated new drug with moderate hypocholesterolemic effect in the general population, was evaluated in hypercholesterolemic (greater than 300 mg/dl) cardiac transplant recipients. nine patients received probucol, 500 mg twice daily, in a single-blind, placebo-controlled trial lasting 20 weeks. six patients responded with cholesterol falls of -20% (mean, -13.2%), and 1 patient showed minimal change. one patient developed cardiac rejection and was excluded, and another responded ... | 2000 | 94402 |
| cognitive impairment and hospital use. | an increasing number of older people are at higher risk of developing alzheimer's disease or another dementias. the resultant cognitive impairment has been well identified as one of the risk factors for nursing home placement but it has not been well studied as a risk for hospitalization. | 2007 | 1951826 |
| data collection in the home health agencies of rhode island--home health agency management system brief. | | 2015 | 4496466 |
| experience with sequential and low-dose-progestogen oral contraceptives. | | 2014 | 4184854 |
| ca 72-4 radioimmunoassay in the diagnosis of malignant effusions. comparison of various tumor markers. | we evaluated the utility of the ca 72-4, cea, ca 125, ca 19-9 and ca 15-3 radioimmunoassays for the detection of tumor-associated antigens (taas) in effusions of malignant vs. benign origin. fluids were obtained from 51 patients with adenocarcinomas, 27 with non-epithelial malignancies, and 68 with benign disorders. the ca 72-4 radioimmunoassay (cut-off value 8.5 u/ml) detected the tag-72 antigen in 51% of adenocarcinoma patients' effusions, while only 1 of 68 benign specimens had an elevated ta ... | 2007 | 2394511 |
| alpha-adrenergic response in patients with ventricular dysfunction. | | 2007 | 1932662 |
| heterogeneity in hormone receptor status in primary and metastatic breast cancer. | | 2013 | 3901267 |
| further characterization of 4-bromomisonidazole as a potential detector of hypoxic cells. | [14c]bromomisonidazole was prepared by direct bromination of [ring-2] [14c]misonidazole in dioxane. the uptake and binding of the two labeled sensitizers were compared in vitro in 1-mm emt-6 spheroids which contain a necrotic core. using liquid scintillation counting it was shown that spheroids incubated with 50 microm [14c]bromomisonidazole concentrated drug above levels in the medium by 1 1/2 hr and achieved maximum concentration by 10 hr with no further increase at 23 hr. spheroids incubated ... | 2014 | 3983371 |
| unusual decor dispels tension. | | 2015 | 4500136 |
| chido, rodgers, and c4 deficiency. | | 1999 | 93815 |
| [methoxypropriocin in the treatment of degenerative bone disease (comparative studies)]. | | 2005 | 1251633 |
| [acth unresponsiveness]. | | 1988 | 211287 |
| capnography and the bain coaxial breathing system. | | 2007 | 1952030 |
| canada: the stress of caring for people with aids. | | 2007 | 2045231 |
| stages in phage r17 infection. v. phage eclipse and the role of f pili. | | 1971 | 4108185 |
| a detailed analysis of four long-term silver cone root canal fillings. | because many failures in root canal therapy have been attributed to the use of silver cones as a filling material, it was decided to examine four roots of three teeth, each of which had been successfully treated endodontically with silver cones ranging from 24 to 34 years previously. these roots, which were resected for periodontal reasons, were examined both under the scanning electron microscope and histologically. examination with the scanning electron microscope revealed that all four cones ... | 2011 | 3165520 |
| adeno-squamous carcinoma pancreas--a case report with literature review. | | 2009 | 2687168 |
| plasma lipids and lipoproteins in young patients with brain infarction. | thirty-two patients aged 60 or less with brain infarction were examined with regard to possible changes in lipoprotein pattern as compared with a reference group. except for a lower concentration of total lipids, cholesterol and high-density lipoproteins in the female patients, no difference was demonstrated in the two groups. in all patients a significant reduction in total lipids, cholesterol, triglyceride and all lipoproteins was demonstrated after the acute cerebrovascular accident presumedl ... | 1989 | 209655 |
| a clinical study of young infants after small intestinal resection. | we prospectively studied 15 infants who, before 3 months of age, underwent resection of the small intestine-proximal in 3 infants, mid in 6, and distal in 6. two died before one year of age. many required prolonged parenteral nutrition, but by one year, 12 of the 13 survivors were on oral feedings only, and seven were above the third percentile for height and weight. developmental delay occurred in the early postoperative period but diminished with time. there was compensatory adaptation of the ... | 1998 | 107303 |
| hla associations with chemically defined ragweed pollen components. | | 1999 | 93812 |
| [the role of non-specific factors in the immune response after smallpox vaccination]. | | 2000 | 94256 |
| [onchocerciasis in america]. | | 2001 | 95137 |
| initial therapy of suspected microbial corneal ulcers. ii. specific antibiotic therapy based on corneal smears. | the encounter of the microorganism with the cornea is a complex event which generates tissue destruction through multiple host and organism-derived mediators. suspicion of microbial invasion, proper utilization of the microbiology laboratory, and initiation of effective antimicrobial agents are the crucial measures in controlling the replicating organism and preserving visual function. | 2001 | 92812 |
| [tumor plasminogen activators and their clinical significance]. | by means of a radio-immunological method the amount of plasminogen activators released by tumours was determined. the concentrations of tumour plasminogen activators was considerably higher in the venous blood of ovarial tumours than in the peripheral blood. in the uterine fluid the uterus cavity the concentration of plasminogen activator was increased in cases with neoplastic endometrium compared to those with normal endometrium. | 2001 | 94895 |
| the carpal tunnel syndrome: part ii. | the carpal tunnel syndrome is a compression of the median nerve within the carpal tunnel with very specific signs and symptoms. anatomical dissection of 156 wrists is presented and then the authors compare their findings with the findings of other investigators. the purpose of this article is not to present results but rather to discuss the anatomic entities involved with the syndrome and to present the open treatment modality. | 2006 | 1550309 |
| dialogue on a theoretical issue: the future of theory development--commentary and response. | | 2007 | 2779892 |
| osmotic swelling of vesicles: its role in the fusion of vesicles with planar phospholipid bilayer membranes and its possible role in exocytosis. | in order for either lipid bilayer membranes or biological membranes to undergo fusion, stresses must somehow be generated in the region of membrane contact. in the fusion of phospholipid vesicles with planar bilayer membranes, the stress can be produced by osmotic swelling of vesicles contacting the planar membrane. on the other hand, fully swollen vesicles may be sufficiently stretched that the additional stress experienced from their adhesion to the planar membrane may in itself suffice to pro ... | 2008 | 2423021 |
| [change in the antigenic structure of streptomycin-resistant mutants of klebsiella ozaenae]. | | 1974 | 4465650 |
| bronchoalveolar lavage for research purposes in the immunocompromised host. | | 2013 | 4028837 |
| [clinical trial of an association of 5-chlorobenzoxazolinone and n-acetyl-para-aminophenol (parafon)]. | | 2014 | 4247248 |
| tamoxifen therapy in premenopausal women with metastatic breast cancer. | forty-three premenopausal women with metastatic breast cancer were treated with tamoxifen (2 x 20 mg daily) as first-line treatment. the patients were not selected on receptor status, which was known in only a few patients. complete response was achieved in six patients and partial response was achieved in seven patients, for a total response rate of 30%. at the time of disease progression (including nonresponding patients), castration was performed as second-line treatment in 24 patients. four ... | 2014 | 3995508 |
| [influencing the effect of digitalis by adrenergic beta-receptor blockade]. | | 2015 | 4390852 |
| [hydatidosis of the cranial vault. two case reports]. | the authors report 2 cases of echinococcosis of the cranial vault, an extremely rare localization of hydatid disease. the parietal bone was involved in one case and the occipital bone in the other. the authors discuss the mechanism and classification of cranial vault echinococcosis. the clinical signs of the disease as well as its radiological appearances and especially its very characteristic ct scan appearances are studied in relation to the literature. | 2007 | 2234264 |
| estimation of missing cone data in three-dimensional electron microscopy. | the range of tilt angles for which projected images of two-dimensionally periodic specimens can be obtained in electron microscopy is limited both by technical aspects, such as goniometer design, and by the more fundamental limitation of object thickness. the lack of a full set of projections causes a missing cone in the reciprocal space data for the object, which will give an anisotropic resolution in a three-dimensional reconstruction and may cause the quality to be impaired by spurious featur ... | 2011 | 3244969 |
| the veterinarian's part in the regulation of the movement of livestock and meat. | | 2015 | 4675709 |
| antabuse contracts for married alcoholics and their spouses: a method to maintain antabuse ingestion and decrease conflict about drinking. | antabuse is widely used in alcoholism treatment as a deterrent to impulsive drinking when the alcoholic encounters some temporary life crisis or other stressful situation. unfortunately, antabuse therapy often is not effective because the alcoholic discontinues the drug prematurely. marital conflicts and arguments, frequently about past drinking or the likelihood of future drinking, are an important stressor that can lead the newly abstinent alcoholic to relapse. the antabuse contract procedure ... | 2013 | 3735473 |
| calcium channel blocking agents and the heart. | | 2014 | 3933699 |
| involuntary movements caused by phenytoin intoxication in epileptic patients. | the case histories of four patients who developed choreoathetoid movements during intoxication with phenytoin are presented. drug intoxication was confirmed in each case by measuring the serum phenytoin concentration. drug interactions were, in part, responsible for the occurrence of intoxication in three of them. phenytoin intoxication is not always easy to recognize, particularly when nystagmus is minimal or absent, as in these four patients. the estimation of the serum phenytoin concentration ... | 1986 | 239101 |
| the representability of laparoscopic ovarian biopsies for the cellular structure and function of the ovaries. | model biopsy specimens from 100 surgically removed ovaries were studied. they were matched in respect of size, dimensions and examination technique to 110 ovarian biopsy specimens obtained during laparoscopy from 60 amenorrhoeic patients. it was found that ovarian biopsy specimens with an all-round edge length of 4 to 5 mm permit usable conclusions in respect of the structure and hence also of the function of normal ovaries. | 2002 | 127563 |
| rickets in a white adolescent. | | 2004 | 523368 |
| computer-aided gene design. | a computer program, which runs on ms-dos personal computers, is described that assists in the design of synthetic genes coding for proteins. the goal of the program is the design of a gene which (i) contains as many unique restriction sites as possible and (ii) uses a specific codon usage. the gene designed according to the criteria above is (i) suitable for 'modular mutagenesis' experiments and (ii) optimized for expression. the program 'reverse-translates' protein sequences into degenerated dn ... | 2005 | 1287664 |
| tumor markers of lung cancer: carcinoembryonic antigen and tumark. | to assess the value of tumor marker determinations in diagnosing lung cancer and monitoring the response to therapy in lung cancer patients, we tested the serum concentration of tumark-reactive protein and carcinoembryonic antigen (cea) in 78 patients with lung cancer and 81 patients with non-malignant diseases. the sensitivity of tumark in detecting the presence of lung cancer was 63.8%, compared to 37.2% for cea (p less than 0.05). the specificity was 91.3% for tumark and 97.5% for cea. the co ... | 2008 | 2592942 |
| feeding clients with severe multiple handicaps in a skilled nursing care facility. | | 2008 | 2963942 |
| [a method of obtaining a plantogram on erga (an electroroentgenographic attachment for x-ray apparatus)]. | | 2009 | 2726228 |
| new abuse of ipecac. | | 2010 | 2866486 |
| chronic urticaria and moderate leukocytoclastic vasculitis associated with c3 nephritic factor activity. | | 2010 | 2817926 |
| [woman of fertile age with pleural effusion and an interstitial lung pattern]. | | 2011 | 3175173 |
| portraits from memory. 11--lieutenant colonel harold j bensted obe, ramc (1888-1966). | | 2011 | 3107672 |
| monocytes and vascular lesions. | current literature has shown increasing indications of the involvement of monocytes in the generation of vascular lesions and atherosclerosis. such involvement appears to be mediated by the ability of monocytes to disrupt the integrity of blood vessel wall, initiate and accelerate blood coagulation processes and/or regulate the growth pattern of blood vessel wall cells. at least in two pathological situations, namely hypercholesterolemia and diabetes mellitus, the association between monocytes a ... | 2012 | 3550691 |
| monocytes and vascular lesions. | current literature has shown increasing indications of the involvement of monocytes in the generation of vascular lesions and atherosclerosis. such involvement appears to be mediated by the ability of monocytes to disrupt the integrity of blood vessel wall, initiate and accelerate blood coagulation processes and/or regulate the growth pattern of blood vessel wall cells. at least in two pathological situations, namely hypercholesterolemia and diabetes mellitus, the association between monocytes a ... | 2012 | 3550691 |
| treatment of lumbar disc disease, 1986. | | 2012 | 3457489 |
| [xeroangiography. technical principals and applied developments]. | the physical patterns ruling the information of a xeroradiographic image allow the visualization of the arterial system with a lower concentration of contrast medium. so you can visualize the arterial branches both with intravenous injection of the usual angiographic concentration of contrast medium or with intraarterial injection of diluted contrast medium at a very low concentration. a prerequisite to successful xeroangiography was the commercial diffusion of a changer for xerox cassettes allo ... | 2013 | 4070698 |
| catecholamines and the heart. | | 2013 | 3801118 |