Publications

TitleAbstractYear
Filter
PMID
Filter
characterization of various horse thyroid forms of cyclic-nucleotide phosphodiesterase [proceedings]. 197992956
isoelectric focusing of oligopeptides: detection by specific stains.by using ultrathin (350 micrometers) polyacrylamide gels, which at the end of the fractionation are pasted to filter paper and dried in an oven at 110 degrees c, and after isoelectric focusing it has been possible to detect oligopeptides in the di- to tetradecapeptide range, which could not be detected by protein staining techniques. this is achieved by developing a series of specific stains for the following amino acids: arg, tyr, his, trp, met and cys. except for met and cys, the detection lim ...197995344
production and chemical studies of protease from bacillus subtilis (sh-6) egyptian strain.bacillus subtilis (sh-6) egyptian strain, isolated from hides, gave the highest protease activity. luxurious growth and protease production were obtained by the use of a medium containing 8% of potato starch, 0,1 m of ammonium phosphate as carbon and nitrogen sources. results indicate that borate buffer exerted a deleterious effect on the protease production. comparing citrate and phosphate buffers, it was found that citrate gave lower protease activity than phosphate. there is a positive respon ...197898932
[ecological aspects of south american trypanosomiasis. xiii. domestic enzootic potential in an area of occurrence of panstrongylus megistus, under epidemiological surveillance]. 1978111341
potency of 10 bcg vaccines as evaluated by their influence on the bacillemic phase of experimental airborne tuberculosis in guinea-pigs. 1979387796
autosomal dominant retinitis pigmentosa: exclusion of a gene from extensive regions of chromosomes 6, 13, 20, and 21.members of a large pedigree of irish origin presenting with early onset type i autosomal dominant retinitis pigmentosa (adrp) have been typed for polymorphic dna markers from chromosomes 6, 13, 20, and 21. for each marker close linkage to adrp has been excluded by pairwise analyses. using distances fixed from well-established genetic maps of these chromosomes and multipoint analyses with two or three contiguous markers, exclusion of adrp was extended to the areas between markers, resulting in th ...19892613243
biopharmaceutical evaluation of sustained-release ethylcellulose microcapsules containing amoxicillin using beagle dogs.a beta-lactam antibiotic, amoxicillin, was microencapsulated with ethylcellulose using a solvent evaporation process in liquid paraffin containing sorbitan tristearate as a dispersing agent, and the microcapsules obtained showed first-order drug release. usage of the previous log-log relationship of cefadroxil between in vitro dissolution half-lives (t50) and the experimental release rate constants (k'r) of the drug in vivo, and the nomogram for the design of satisfactory sustained-release prepa ...19892632091
biopharmaceutical evaluation of sustained-release ethylcellulose microcapsules containing amoxicillin using beagle dogs.a beta-lactam antibiotic, amoxicillin, was microencapsulated with ethylcellulose using a solvent evaporation process in liquid paraffin containing sorbitan tristearate as a dispersing agent, and the microcapsules obtained showed first-order drug release. usage of the previous log-log relationship of cefadroxil between in vitro dissolution half-lives (t50) and the experimental release rate constants (k'r) of the drug in vivo, and the nomogram for the design of satisfactory sustained-release prepa ...19892632091
current management of salivary gland tumors. part 2.the authors base their treatment of salivary gland malignancies on the size of the primary and the histopathologic diagnosis. group 1 includes smaller tumors in the t1 and t2 classification with cell types that are associated with slow growth. a parotidectomy is usually sufficient therapy for tumors in this group. group 2 contains t1 and 2 tumors with more aggressive behavior. total parotidectomy is indicated here, with postoperative radiotherapy. t3 tumors and patients with nodal metastasis or ...19892701414
high-level production of the ecori endonuclease under the control of the pl promoter of bacteriophage lambda.escherichia coli strains overproducing the ecori restriction endonuclease have been constructed, using lambda pl promoter expression vectors. in a first step we constructed endri::lacz gene fusions by fusing the n-terminal part of the endri gene with a lacz gene fragment, whereafter the hybrid gene was positioned randomly under the control of the pl promoter to optimize the level of expression. these plasmids direct the synthesis of large amounts of fusion protein approaching 30% of the total ce ...19852996986
calmodulin-mediated cadmium inhibition of phosphodiesterase activity, in vitro.ion-stripped bovine brain calmodulin (cam) binds 4 moles cd2+ as well as 4 moles ca2+ per mole protein, with similar affinity; in the presence of 1 mm mg2+ the molar binding ratio of cam for ca2+ decreased to 3, the apparent k0.5 for ca2+ nearly doubled, but the binding characteristics of cam for cd2+ were not changed. saturating concentrations ca2+ did not affect the molar binding ratio of cam for cd2+, but increased the apparent k0.5 for cd2+; vice versa, saturating concentrations cd2+ decreas ...19873034196
glucagon, glicentin, proglucagon, pyy, pp and propp-icosapeptide immunoreactivities of rectal carcinoid tumors and related non-tumor cells.glucagon/pp-related peptides were detected immunohistochemically in 18 out of 22 cases of rectal tumors investigated. the reactive tumors showed prevalence of trabecular or mixed trabecular-acinar structure and moderate staining with grimelius' silver and lead-hematoxylin. three of the remaining 4 cases were characterized by reactivity for 5-hydroxytryptamine only, prevalence of a solid nest structural component and intense staining with grimelius' silver technique and lead-hematoxylin. fifteen ...19872882565
the behaviour of sensory ganglia in relation to their environment.the nodose ganglion was removed from rats and transplanted into the denervated tongue and into the denervated or innervated sternocleidomastoid muscle. in another procedure the ganglion was sutured to the distal hypoglossal or sciatic nerve. the ganglia failed to develop motor end-plates on denervated muscle. they did, however, induce formation of taste buds on the lingual epithelium. the regenerated nerve fibres ramified extensively within the connective tissue, invading perivascular tissue and ...19892606773
nifedipine: variability in its kinetics and metabolism in man. 19892519350
antibodies to distal carboxyl terminal epitopes in the v-fms-coded glycoprotein do not cross-react with the c-fms gene product.the product of the v-fms oncogene is an integral transmembrane glycoprotein that is closely related to the cell surface receptor for the macrophage colony stimulating factor, csf-1. a fragment of the v-fms gene encoding a major portion of the extracellular amino terminal domain, the membrane-spanning segment, and the entire carboxyl terminal tyrosine kinase domain of the glycoprotein was molecularly cloned into an inducible prokaryotic expression plasmid. polypeptide products consisting only of ...19862425481
university of north carolina caries risk assessment study. iii. multiple factors in caries prevalence.the baseline caries experienced of approximately 5,000 children in south carolina and maine was used as the dependent variable in caries risk assessment analyses. clinical, microbiologic, and demographic factors served as independent variables in a multivariate relationship to caries through regression and discriminant function analyses. four factors--number of dental visits by the child in the past year, presence of white spot lesions, and both the urgency of need for restorative care and the f ...19911920265
design of site-specific protein drugs.the ability to clone and express proteins at high levels of abundance and purity has led to their increasing consideration as therapeutic agents. the use of various protein engineering and recombinant dna techniques has enabled progression to where proteins can be tailored so that they have not only the ability to interact with a unique (extra)cellular component in order to produce a pharmacological effect, but their structure can be altered so as to achieve a selective biological disposition. t ...19911815386
case records of the massachusetts general hospital. weekly clinicopathological exercises. case 29-1986. an asplenic woman with evidence of sepsis and diffuse intravascular coagulation after a dog bite. 19863724816
characterization of the human gene for a newly discovered carbonic anhydrase, ca vii, and its localization to chromosome 16.six carbonic anhydrase (ca) isozymes (ca i-vi) in mammals and other amniotes have been described. we have isolated an additional ca gene from a human genomic library and designated its putative product carbonic anhydrase vii (ca vii). the gene is approximately 10 kb long and contains seven exons and six introns found at positions identical to those determined for the previously described ca i, ca ii, and ca iii genes. the finding of a 17-bp gt-rich segment in a position 28 bp downstream of the p ...19911783392
[hypothetical concept: the physiopathological entity of monoaminergic psychoses].the importance of amino acid transport across the blood-brain barrier as the limiting factor in the metabolism of monoamines has been emphasized by many recent publications. particularly critical is the transport of tryptophan, since tryptophan hydroxylase is not saturated. this transport is regulated by complex mechanisms, both at the periphery (total and free plasmatic levels and levels of the other essential amino acids) and centraly (by feedback mechanism initiated at the pre- and post-synap ...19751082812
osteomyelitis and arthritis caused by salmonella typhimurium in a crow.salmonella typhimurium was isolated from an arthritic elbow joint of a crow (corvus brachyrhynchos) which also had bilateral osteomyelitis of proximal tibias. the prevalence of salmonella organisms in wild birds is reviewed briefly.1978368353
evidence for hydroxyl radical generation by human monocytes.a number of highly reactive oxygen species have been implicated in the oxygen-dependent mechanisms involved in bactericidal activity of phagocytic leukocytes. hydrogen peroxide and superoxide, two agents known to occur during phagocytosis, are thought to interact to generate hydroxyl radical, singlet oxygen, and other potentially reactive molecules. using an assay system of ethylene generation from methional, cell preparations of human monocytes were demonstrated to generate hydroxyl radical or ...1977194926
the influence of age on the wound healing of experimental myocardial infarction in rats.in 6-weeks-old, 5-months-old and 21-months-old rats myocardial infarction was induced by coronary artery ligature. after performing the ligature the animals were administered 3h-thymidine, 3h-proline or 35s-sulphate at different times. the following parameters were determined: number of dna- and tropocollagen-synthesizing connective tissue cells at the infarction border and at the infarction site; mean silver grain density above the nuclei or cells; duration of a cycle; number of mitoses, and in ...1975134906
cerebral perfusion pressure: a hemodynamic mechanism of mannitol and the postmannitol hemogram.sixteen patients each received infusions of 1 g of mannitol per kg over 5 to 10 minutes, and serial determinations of intracranial pressure (icp), systemic arterial blood pressure (sabp), central venous pressure, cerebral perfusion pressure (cpp), hematocrit, hemoglobin, serum na+, k+, osmolarity, and fluid balance were carried out for 4 hours. urine output was replaced volume for volume with 5% dextrose in 0.45% nacl solution. we tested the hypothesis that patients with high (greater than or eq ...20103116451
[primary transport of acute patients. optimal use of rescue resources exemplified by the canton of graubünden]. 20113927607
inhibition of passive lung anaphylaxis in the rat by ay-25,674.the antiallergic properties of ay-25,674 were studied in a model of passive lung anaphylaxis. ay-25,674 caused a dose-related inhibition of antigen-induced bronchoconstriction in the passively sensitized rat. ay-25,674 was found to be twice as potent as disodium cromoglycate (dscg) when injected intravenously. the oral administration of ay-25,674 also effectively inhibited antigen-induced bronchoconstriction. a tachyphylactic effect of repeated administration was found when the rats were pretrea ...1979106941
insurers, hmos and bc/bs plans talk about aids. 20102910793
interaction of phenosafranine with nucleic acids and model polyphosphates. iii. heterogeneity in phenosafranine interactions with dna base pairs.fluorescence and circular dichroism spectral measurements, thermal denaturation studies and binding competition experiments with netropsin and actinomycin d were carried out in systems containing phenosafranine bound to dna's differing in base composition. the investigated properties exhibit a heterogeneity related to the content of a.t and g.c pairs in dna and to the nature of phenosafranine binding modes. at low level of saturation of binding sites (r less than 0.1) phenosafranine does not sho ...1979106900
immunological heterogeneity of the subunits of limulus polyhemus haemocyanin [proceedings]. 200192962
[current approaches to immunological diagnosis of autoimmune and immune complex diseases]. 20102974642
the under-reporting of alcohol use: the role of organic mental syndromes.the under-reporting of alcohol use has been viewed as the consequence of alcoholic denial. alcoholic denial has been conceptualized as an unconscious ego defense. in this paper the authors present data suggesting that the under-reporting of alcohol use may be, in certain cases, the result of the influence of the organic mental syndromes commonly associated with alcoholism.20134053972
evaluation of pseudorabies viral antigens in the agar gel immunodiffusion test.procedures designed to extract pseudorabies viral (prv) antigens from prv-infected tissue cultures were investigated to determine whether differences in extraction method had an effect upon the final concentrated antigenic product. all four of the preparations made from prv-infected tissue culture cells (trypsin extract and disrupted cells) or entire prv-infected cultures (polysorbate 80 extract and (nh4)2so4 precipitate) contained relatively large amounts of the same antigen, whereas cell-free ...197992905
oxygen metabolism by the anaerobic bacterium veillonella alcalescens. 197831846
rating of the lesions in senile dementia of the alzheimer type: concordance between laboratories. a european multicenter study under the auspices of eurage.the study reported was intended to compare the impressions and analyses of investigators from 11 different laboratories on 2 slides, each from 6 cases with varying quantities of neuropathological change of the type found in alzheimer's disease and normal ageing. the material came from 6 selected female patients over 75 years of age all of whom had been examined in detail and assessed by the blessed test score. two were severely demented, 2 mildly demented and 2 were considered to be normal. unst ...20061698217
ion channel selectivity, permeation, and block. 20061382215
varied appearance of cardiac pseudoaneurysms on blood pool images.three cases of cardiac pseudoaneurysms were presented, with findings at the time of gated blood pool imaging. in only one of three was there the finding of a small neck connecting the ventricular cavity with the pseudoaneurysm. in the other two patients, there was a considerably larger communication. the size of the pseudoaneurysm itself was also of little diagnostic assistance. in one case it was small, while in a second patient it was larger in size. the third case revealed a pseudoaneurysm of ...20133595025
[crushing and avulsions of segments of the limbs in patients with polytrauma]. 20144069611
technical aspects of dr. kryter's paper "impairment to hearing from exposure to noise" with respect to the niosh statistics. 20164712552
echinococcus granulosus: absorption of cycloleucine and alpha-aminoisobutyric acid by protoscoleces.protoscoleces of echinococcus granulosus absorb the amino acids cycloleucine and alpha-aminoisobutyric acid (aib) by a combination of mediated uptake and diffusion. after correcting for the latter, values for kt and vmax of 0.124 mm and 0.947 nmoles/mg protein/2 min for cycloleucine were calculated; corresponding values for aib were 0.039 mm and 0.139 nmoles/mg protein/2 min. both amino acids were accumulated against a concentration gradient and a comparison of kt and ki values determined in mut ...19863083393
localization of the kras2 oncogene in the domestic rabbit (oryctolagus cuniculus).the kras2 gene was localized in the rabbit by chromosomal in situ hybridization, using a 3h-labeled human cdna probe. there were 201 silver grains on 144 metaphase spreads; 12.9% of the grains resided on chromosome 16, and 54% of these grains were located close to the centromere at 16p11----q11. statistical analysis indicated that labeling at this region represents a significant deviation from a random distribution and thus provided evidence for the assignment of kras2 to 16p11----q11. in additi ...19883073912
prostaglandin inhibition of acid is camp dependent.prostaglandin e (pge) potently inhibits acid secretion stimulated by histamine, but not by acetylcholine or gastrin, and is accompanied by decreased intracellular camp. adenylate cyclase receptor systems are composed of three complex proteins: cell receptor, nucleotide binding protein, and the catalytic subunit. the exact mechanism of pge interaction with this complex remains unclear and elucidation of this site of action is the purpose of this study. we utilized molecular probes directed at the ...19873035281
haemolytic uraemic syndrome associated with faecal cytotoxin and verotoxin neutralizing antibodies.forty-nine patients with a diagnosis of idiopathic haemolytic uraemic syndrome (hus) were investigated to determine evidence of infection by verotoxin-producing escherichia coli (vtec). free faecal cytotoxin active on vero cells (vt) was detected in 15 out of 49 patients (31%). seroconversion or high titres of vt-neutralizing antibodies were detected in 11 out of 18 patients (61%). the results of the present study suggest an association between hus and infection by vtec.19883153027
trefoil balloon for percutaneous valvuloplasty.a new balloon (trefoil balloon) was developed to avoid complete interruption of blood flow during percutaneous balloon valvuloplasty. it consists of three identical 2- to 4-cm-long angioplasty balloons mounted in a parallel fashion on a single catheter. filled simultaneously, they assume the cross section of a rosette, allowing for continued blood flow. trefoil balloons of various sizes were tested in five dogs (aorta and aortic valve). they created a gradient ranging from 5 to 40 mmhg where con ...19862944597
characterization of the copper-thiolate cluster in yeast metallothionein and two truncated mutants.cu-metallothionein was purified from saccharomyces cerevisiae harboring plasmids containing mutated cup1 metallothionein genes resulting in deletions at the carboxy-terminal end of the polypeptide. the truncated polypeptides are recovered as polypeptides of 35 and 48 residues in length. the cu-s cluster in the wild-type metallothionein and the two truncates were characterized. the truncated proteins, designated t35 and t48, contain 4 and 2 fewer cysteinyl residues, respectively, compared to the ...19883283130
dna-dna hybridization studies and phenotypic characteristics of strains within the 'streptococcus milleri group'.twenty-five strains resembling 'streptococcus milleri' were compared by dna-dna hybridization, by whole-cell-derived polypeptide patterns on sds-page, and by biochemical tests. four homology groups were revealed by dna-dna hybridization. dna homology groups 1, 2 and 3 were closely related and contained the type strains ncdo 2226 (streptococcus constellatus), ncdo 2227 (streptococcus intermedius) and nctc 10713 (streptococcus anginosus), respectively. dna homology group 4 consisted of four strain ...19892632666
change in collagen synthesis of human chondrocyte culture. i. development of a human model, demonstration of collagen type conversion by immunofluorescence.a research system constituted entirely of components of human origin was developed to study conversion of collagen synthesis by human chondrocytes. type specificity of affinity chromatography-purified antibodies to human type ii or type i collagen was proven by elisa inhibition and immunofluorescence analysis. human chondrocytes were isolated from articular cartilage and kept in monolayer cultures for eight subpassages. conversion of type ii to type i synthesis by chondrocytes was investigated b ...19863532286
receptor-independent metabolism of platelet-activating factor by myelogenous cells.human neutrophils incorporate and metabolize platelet-activating factor (paf). we dissociated these events from paf binding to its receptors. cells were pretreated with either pronase, a paf antagonist (l652731), or excess paf. this reduced paf receptor numbers by 70 to almost 100% but had no comparable effect upon the neutrophil's ability to metabolize paf. furthermore, hl-60 cells efficiently metabolized, but did not specifically bind, paf. thus, paf receptor availability did not correlate wit ...19892546802
change in collagen synthesis of human chondrocyte culture. i. development of a human model, demonstration of collagen type conversion by immunofluorescence.a research system constituted entirely of components of human origin was developed to study conversion of collagen synthesis by human chondrocytes. type specificity of affinity chromatography-purified antibodies to human type ii or type i collagen was proven by elisa inhibition and immunofluorescence analysis. human chondrocytes were isolated from articular cartilage and kept in monolayer cultures for eight subpassages. conversion of type ii to type i synthesis by chondrocytes was investigated b ...19863532286
predation on rhodnius prolixus (hemiptera: reduviidae) by the spider theridion rufipes (araneida: theridiidae). 19873546692
the purification and characterization of recombinant human renin expressed in the human kidney cell line 293.the cdna encoding human preprorenin has been introduced into the adenovirus-transformed human kidney cell line 293. the recombinant 293 cells expressed and secreted prorenin; trypsin was used to activate the secreted prorenin to renin in vitro. the recombinant protein was purified to homogeneity by a single affinity chromatographic step. using synthetic tetradecapeptide, the km was 57.1 +/- 9.3 microm and the kcat was (7.48 +/- 1.57) x 10(3)/hr. activation with trypsin resulted in a secondary cl ...19902203348
assessment of abdominal fat deposition in female cynomolgus monkeys.computed tomography (ct) was used to assess abdominal fat distribution in adult, female cynomolgus macaques (macaca fascicularis). the technique used was similar to that applied in human beings and allowed intra-abdominal, subcutaneous and total abdominal fat to be quantitated in 1 cm thick sections. correlations between single scans and the average of scans at several levels ranged from r = 0.96 to r = 1.00, indicating that a single scan is representative of abdominal fat distribution. signific ...19912045214
thallium-201 accumulation by epidermoid inclusion cyst.an elderly male undergoing re-evaluation for coronary artery disease demonstrated an extra-cardiac focus of 201tl accumulation during the performance of a planar myocardial perfusion scan. this corresponded to a subcutaneous lesion of the left posterior thorax found on a concurrent computerized axial tomographic (cat) scan and upon surgical excision proved to be an "epidermoid inclusion cyst." a follow-up nuclear scan failed to reveal any residual extracardiac tracer localization. confusing this ...19921403158
human milk-derived lactoferrin inhibits mitogen and alloantigen induced human lymphocyte proliferation.purified lactoferrin (lf), isolated from human milk, was tested for its effect on human t-lymphocyte proliferative responses to phytohemagglutinin (pha) and to alloantigens in mixed lymphocyte culture. lf inhibited proliferation in both assays in a dose-dependent manner. the suppressive effect was not due to lf mediated cytotoxicity since washing cells that had been pre-incubated with lf restored their proliferative activity. lf was most effective in suppressing the pha response when added withi ...19872963123
[importance of studying the sputum of pneumonia and bronchitis patients]. 20144002152
an erythrocyte membrane-protein anomaly in march haemoglobinuria.in three patients with march haemoglobinuria a well-defined protein abnormality has been revealed by high-resolution sodium-dodecyl-sulphate/polyacrylamide-gel electrophoresis.200091785
investigation and treatment of a multiple limb birth.we report a baby born with three fully developed normally functioning legs. the third leg was attached to the baby's sacrum via an iliac bone at the site of a spina bifida. a primitive perineum was present. innervation of the limb was via a sacral hiatus with a myelomeningocele. a rudimentary peritoneal sac was found at operation containing a blind loop of bowel suspended by a mesentery. the additional leg was found to have no cortical representation using somatic evoked potentials although lumb ...20071892571
cancer incidence and lifespan vs. alpha-particle dose in beagles.young adult beagles were injected with graded activities of 239pu, 241am, 228th, 228ra or 226ra and observed throughout their lifespans. the vast majority of the dose was from alpha particles. the lifetime incidence of bone sarcoma increased with average skeletal dose, more or less linearly up to high incidence for 239pu, 241am, 228th and 226ra, but sigmoid fashion for 228ra. based on average skeletal dose, the toxicity of the emitters relative to 226ra = 1.0 was 239pu = 16.6 +/- 4.5, 241am = 5. ...19873570798
[new aspects and controversies on the vascularization of the white pulp of the spleen in the rat].the authors have studied the arterial supply of splenic white pulp of the rat, by means of optic and scanning electron microscopy. this work shows that the marginal zone is a free and interstitial circulatory one that envelopes completely the periarterial lymphocyte sheets. these ones are vascular exclusion areas although crossed by vessels, probably impermeable, that pour their contents at the inner border of the marginal zone. it was impossible to find a so called "marginal sinus" neither a co ...19853842273
[cloning of human leukocyte interferon cdna and a strategy for its production in e. coli]. 19853906813
[cloning of human leukocyte interferon cdna and a strategy for its production in e. coli]. 19853906813
analysis of oxidized and reduced pyridine dinucleotides in rat liver by high-performance liquid chromatography.nadp+, nad+, nadph, and nadh were assayed by selective extraction and isocratic reversephase hplc. sample preparation involves freeze clamping and powdering liver under liquid nitrogen, extraction of dinucleotides with basic (reduced species) or acidic (oxidized species) cold ethanol, and injection onto the hplc for quantitation at 340 nm (reduced) and 254 nm (oxidized). the mobile phase for the oxidized species is ph 5.25, 0.2 m ammonium phosphate/methanol, and for the reduced species is ph 6.0 ...19854096371
[progress in the symptomatic treatment of bronchial asthma]. 19724403663
[demonstration of the relationship between the origins of cherry leaf-roll virus and elm mosaic virus]. 19724628106
acupuncture treatment for aerotitis media. 20133834237
[contributions to clinical myology. classification]. 20113136470
[investigations into the biological disintegration of organic natural substances by aquatic hyphomycetes (author's transl)].the ability of 5 aquatic hyphomycetes to produce amylase, pectinase and cellulase was investigated. all the tested strains were weak producers of amylase and good producers of pectinase, whereas degradation of cellulose was only found with two strains.200094494
a report on genetic registers. based on the report of the clinical genetics society working party. 1998106123
[anthropological studies on the cossacks in bulgaria]. 2002126579
anal tonometry and anal tone in clinically healthy persons and patients with chronic diseases of the digestive apparatus. 1999103788
a comparison of wisc and wisc-r subtest scatter. 2004438638
[how to prevent sexually transmissible diseases]. 20133853295
imaging metastases of thyroid carcinoma. 20133668671
[what should be done in a meniscal lesion?].the treatment of meniscal lesions closely depends on the context in which they occur. in isolated lesions of the medial meniscus, meniscectomy under arthroscopy remains the best method. when the meniscal lesion complicates a rupture of the anterior cruciate ligament, meniscal suture associated with reconstruction of the ligament may be contemplated. in case of degeneration of the medial meniscus or lesion of the lateral meniscus, various therapeutic approaches may be envisaged.20082602876
studies of impedance in cardiac tissue using sucrose gap and computer techniques. ii. circuit simulation of passive electrical properties and cell-to-cell transmission.the impedance measured in a strip of heart tissue from the moth hyalophora cecropia is fitted by circuit models of several configurations. the circuits include: (a) a single r-c circuit (b) a double r-c circuit (c) terminated transmission lines, and (d) a pattern of cells with cell-to-cell transmission paths. the last of these is found to give the best fit. calculation of the model impedances and optimization of element values are performed by a computer. the possibility that the mechanism of ce ...20164813160
screening for ischaemic heart disease risk factors at a health fair: low attendance by those at highest risk.among people attending a heart disease screening project at a health fair in sheffield, only 22 of 425 (5.2%) lived in areas with more than 25% of the population belonging to social classes iv or v. the incidence of heart disease is known to be particularly high in these areas, where 15.1% of the total population live. by analysis of the attendance rates from districts other than those immediately adjacent to the site of the health fair, we found that the strength of this inverse correlation inc ...20082607301
final maturation and ovulation provoked by supply of homologous hypophysis in hoplias m. malabaricus (pisces, erythrinidae).the final maturation and the ovulation were induced in recently collected specimenes of hoplias m. malabaricus that show oocytes with complete vitellogenesis, by using homologous hypophysis. the hormonal supply was a gradual and positive results were obtained with 9 to 10 hypophysis/kg injected according to 3 different methods. the time of oocytes' maturation from the first dose ranges between 32 and 60 hours a 18 degrees c. the stages of maturation of the oocyte were controlled by intraovaric c ...20092762598
nifedipine induced gingival hyperplasia. 19983182672
participation of endothelial cells in murine schistosomiasis.the endothelial cells participate in the morphological events occurring during murine schistosomiasis, taking part in the development of hepatic periovular granuloma. the cells also show an increase in the expression of factor viii-related antigen in the portal vessels and hepatic sinusoids during the infection. endothelial cells are suggested to play an important role in the pathogenesis of the disease and in the balance of the coagulant-anticoagulant mechanisms which favor the intravascular su ...20113150298
single unit response of suprachiasmatic neurons to arginine vasopressin (avp) is mediated by a v1-like receptor in the hamster.a large population of local circuit neurons within the suprachiasmatic nucleus (scn) exhibit immunopositive staining for arginine-vasopressin (avp). avp has been reported to be released from scn neurons in a circadian pattern that peaks during the subjective day. using an in vitro hypothalamic slice preparation, the present study investigated how scn neurons respond to avp over the circadian cycle and whether the response to avp is mediated by v1- or v2-like avp receptors. exposure of the slice ...20092702494
nephrotoxic drugs.the nephrotoxic effects of cyclosporine, aminoglycoside antibiotics, cisplatin, amphotericin b, beta-lactam antibiotics and indomethacin are reviewed. these drugs were chosen because they are among the most frequent causes of renal injury in children. in addition, their nephrotoxicity is caused by different mechanisms. several generalizations can be made, however. first, agents which cause tubular damage tend to be synergistic in their toxic effects. this synergism is seen when several nephrotox ...20113153061
erythrocyte sedimentation rate and plasma fibrinogen in animals. 2004522104
[ecg changes in chronic polyarthritis compared to a healthy control group].ecg from 200 patients with radiologically and clinically definite rheumatoid arthritis were compared with those from a healthy group with the same age and sex distribution. the frequency of pathological changes of the ecg was found to be the same in both groups. therefore doubt remains whether the pathological changes of the ecg can be attributed to rheumatoid arthritis.200092110
lisuride in parkinson's disease. 200091855
genetic toxicology in industry: perspectives and initiatives. 20133960894
[operative management of esophageal perforations]. 20144017775
past history and future trends in cme. 2000101942
imipramine in absence and myoclonic-astatic seizures.a double-blind crossover study with imipramine was conducted in 10 patients with absence and myoclonic-astatic seizures who had not responded to conventional medications. imipramine produced a significant initial decrease in seizure frequency in 5 of the 10 patients, and in 2 patients the beneficial effect was maintained for more than 1 year. an open trial of imipramine in another 16 patients showed an initial reduction in seizure frequency in 10 patients (63 percent), and this decrease persiste ...200199690
current concepts in portal hypertension. 1998107346
[anomalous branching of the inferior thyroid artery from the left vertebral artery].in a 53 years old woman hospitalized for a suddenly developed picture of vascular insufficiency in the verterobrobasillary vascular bed the authors detected an anomalous division of the left vertebral artery from aortic arch. moreover, at the level of thyroid gland there was the division of inferior thyroid artery from the vertebral artery. we express the opinion that the finding did not participate in the clinical symptomatology.20062225222
heavy- and free light-chain myeloma associated with peripheral polyneuropathy.peripheral polyneuropathy, a rare complication of multiple myeloma, is generally associated with heavy-chain m-proteins and, in very rare instances, with free light-chain myeloma proteins. here we describe a case of multiple myeloma and polyneuropathy with both monoclonal igg and free lambda light chains in the blood. the patient also had free lambda light chains in the cerebrospinal fluid and urine.20102848651
topical hemostatic agents for dermatologic surgery. 20102921403
why aged men become impotent.despite frequent erectile impotence in aged men, etiologic data are scarce. we evaluated 121 impotent male veterans (mean age, 68 +/- 5.3 years) to obtain information on potential pathophysiologic mechanisms. subjects related a complete medical history and underwent physical examination, metabolic assessment, nocturnal penile tumescence monitoring, and vascular and neurologic assessment. the most frequent cause of impotence was the coexistence of neurologic and vascular disorders (30.3%). other ...20092786397
[aplastic anemia treated by isogeneic or allogeneic bone marrow transplantation (author's transl)]. 2004368376
ultrasonographic assessment of osteoporosis. 20061393241
fournier's gangrene of the scrotum following traumatic urethral catheterisation. 20133656248
myelographic cervical nerve root deformities.myelograms of nerve roots and adjacent subarachnoid space were reviewed to characterize 231 cervical root deformities from both symptomatic and asymptomatic patients. good correlation between specific features of root deformities and clinical significance could not be demonstrated. some features were slightly suggestive of clinical significance but occurred in a sufficient number of asymptomatic patients to make them unreliable. the most accurate determinants of root deformity significance are c ...1997168615
editorial: the significance of food poisoning in canada. 20164841214
[the role of the v. m. bekhterev school in the formation of pathopsychology]. 20154592883
subaortic aneurysm of the left ventricle.a subaortic aneurysm of the left ventricle resulting in massive hemopericardium is described. the anatomy of the aortic anulus, aortic valve, and pericardial reflections at the base of the heart are constructed in a manner that allows the migration of blood from the left ventricle, through an area of aortic anular dehiscence, resulting in the formation of a false aneurysm. the pertinent anatomy is described, as well as pathogenesis and similar cases in the literature.20113207485
thanatophoric dwarfism: a parent's point of view. 20133996686
Displaying items 1 - 100 of 145