| characterization of various horse thyroid forms of cyclic-nucleotide phosphodiesterase [proceedings]. | | 1979 | 92956 |
| has myelin basic protein received a fair trial in the treatment of multiple sclerosis? | autosensitization to some central nervous system antigen still remains one of the best hypotheses for the continuing pathogenesis of multiple sclerosis (ms). enough is now known about the cause, pathogenesis, and treatment of experimental allergic encephalomyelitis (eae) to test this hypothesis. reports of therapeutic failure of the encephalitogen myelin basic protein (bp) in the treatment of ms have their counterparts in similar therapeutic failures in eae. only highly inbred strain 13 guinea p ... | 1979 | 93873 |
| biochemical mechanism of platelet activation. involvement of contractile proteins. | the present state of knowledge of the biochemical mechanism of platelet activation (adhesion, shape change, microspike formation, aggregation, release reaction, clot retraction) is presented under involvement of contractile proteins. the working hypothesis on the contractile mechanism of platelet activation is explained. | 1979 | 94868 |
| production and chemical studies of protease from bacillus subtilis (sh-6) egyptian strain. | bacillus subtilis (sh-6) egyptian strain, isolated from hides, gave the highest protease activity. luxurious growth and protease production were obtained by the use of a medium containing 8% of potato starch, 0,1 m of ammonium phosphate as carbon and nitrogen sources. results indicate that borate buffer exerted a deleterious effect on the protease production. comparing citrate and phosphate buffers, it was found that citrate gave lower protease activity than phosphate. there is a positive respon ... | 1978 | 98932 |
| isolation and characterization of a pulmonary glycoprotein from human amniotic fluid. | a glycoprotein of the molecular weight of 36 000 has been isolated from human amniotic fluid. the glycoprotein was found to contain sialic acid, galactose, mannose, fucose, glucosamine, hydroxyproline and relatively high amounts of glycine. end-group analyses resulted in a single nh2-terminal residue indicating that the glycoprotein was homogeneous. the data indicate that this unique collagen-like glycoprotein, which is immunologically identical to a major alveolar glycoprotein found in alveoli ... | 1978 | 103578 |
| effects of ryanodine on model systems derived from muscle-v. reconstituted actomyosin and alpha-actinin. | | 1975 | 122894 |
| fluorescence of human liver alanine aminopeptidase. | fluorescence of human liver alanine aminopeptidase has been attributed to tryptophan fluorescence. the fluorescence maximum is at 330 nm, 20 nm lower than that for free tryptophan, suggesting that most of the enzyme tryptophans are in a nonpolar environment and are shielded from solvent. quenching of enzyme fluorescence by iodide, pyridine, and n-methyl nicotinamide also demonstrates that enzyme tryptophan residues are largely buried and inaccessible to solvent. those accessible are in negativel ... | 1977 | 143669 |
| loss of integrated viral dna sequences in polyomatransformed cells is associated with an active viral a function. | rat cells transformed by polyoma virus contain, in addition to integrated viral dna, a small number of nonintegrated viral dna molecules. the free viral dna originates from the integrated form through a spontaneous induction of viral dna replication in a minority of the cell population. its presence is under the control of the viral a locus. to determine whether the induction of free viral dna replication was accompanied by a loss of integrated viral dna molecules in a phenomenon similar to the ... | 1979 | 225038 |
| mitochondrial protein-synthesizing machinery in saccharomyces cerevisiae grown in different metabolic conditions. variability of seryl-trna and alanyl-trna isoacceptor patterns. | 1. the isoacceptor patterns of mitochondrial seryl and alanyl-trnas from saccharomyces cerevisiae grown under different conditions and committed to fermentative or respiratory metabolism have been studied by reversed-phase chromatography. 2. an extensive variability of the chromatographic patterns of the four isoacceptors for serine and of the three isoacceptors for alanine has been observed as a function of carbon source and stage of growth, but the main differences were observed in the differe ... | 1979 | 381000 |
| the contribution of the 'second' visual system to directed visual attention in man. | the visual functions of a patient suffering from a brain lesion incorporating the left n. pulvinar was examined in order to assess the contribution of this structure to human vision. with the exception of the following abnormalities visual functions were normal. first, there was a decrease in the critical flicker frequency in the periphery (but not in the parafoveal region) of the right visual hemifield, that is, that contralateral to the pulvinar lesion. however, the second and most striking ch ... | 1979 | 509197 |
| isolation of corynebacterial enzymes from cultivation media by gel filtration and ion-exchange chromatography. | | 1979 | 524393 |
| the in vitro and in vivo biotransformation of n-deacetyl-n-formylcolchicine. | the major pathway of metabolic transformation of n-deacetyl-n-formylcolchicine is the oxidative cytochrome p450 dependent o-demethylation of substituents in the aromatic ring a and tropolone ring c. it was found that o-demethylation (both, in vitro and in vivo) takes place predominantly in the aromatic ring, especially at position 2. | 1992 | 1301351 |
| hemodynamic effects on hepatic blood flow of a selective beta 2-adrenoceptor agonist, clenbuterol, in rat. | acute clenbuterol administration (50 micrograms/kg, i.v.) to anesthetized normotensive rats, produce a marked reduction in the mean blood pressure, (mbp), about 58 mm hg. indocyanine green clearance analysis (control, 1.83 +/- 0.15: clenbuterol, 1.10 +/- 0.20 ml/min/100 g, p < 0.05) showed that the action in the hepatic vascular bed is opposite to its systemic vasodilator effects. the hepatic blood flow (hbf) appears significantly reduced (control, 8.24 +/- 0.35: clenbuterol, 3.83 +/- 0.71 ml/mi ... | 1992 | 1301352 |
| dermatophytosis due to trichophyton rubrum in northern greece during the decade 1981-1990. | during the years 1981-1990 trichophyton rubrum was the most frequent causative agent of dermatophytic infections in northern greece, especially in cases of tinea pedis, cruris, corporis, and unguium, as well as dermatophytosis of the hands. between sexes there was a prevalence in women in tinea pedis and toenail infections. men were particularly infected in the groin, the hands and the face. the chronic follicular dermatophytosis in the lower legs was also presented in women, but tinea corporis ... | 1992 | 1302814 |
| [the microbiological purification of industrial sulfur-containing sewage]. | | 1992 | 1303100 |
| regulation of hepatic lipid metabolism by cytokines that induce the acute phase response. | | 1992 | 1303901 |
| human prolactin gene expression. the use of an alternative noncoding exon in decidua and the im-9-p3 lymphoblast cell line. | the prolactin (prl) gene is normally expressed in the anterior pituitary lactotrope and the decidualized stromal cell of the human endometrium. we have recently described the ectopic expression of the human prl gene in a b-lymphoblastoid cell line, im-9-p. the im-9-p and decidual prl mrnas are approximately 150 nucleotides longer than the pituitary transcript. the protein coding sequence of the im-9-p and decidual prl cdnas is identical to the pituitary prl message, and the 3'-untranslated regio ... | 1990 | 1697858 |
| human prolactin gene expression. the use of an alternative noncoding exon in decidua and the im-9-p3 lymphoblast cell line. | the prolactin (prl) gene is normally expressed in the anterior pituitary lactotrope and the decidualized stromal cell of the human endometrium. we have recently described the ectopic expression of the human prl gene in a b-lymphoblastoid cell line, im-9-p. the im-9-p and decidual prl mrnas are approximately 150 nucleotides longer than the pituitary transcript. the protein coding sequence of the im-9-p and decidual prl cdnas is identical to the pituitary prl message, and the 3'-untranslated regio ... | 1990 | 1697858 |
| the effect of age on motor neurone death following axotomy in the mouse. | the ability of mouse motor neurones to survive axotomy during the first month of life was studied. the motor neurones that lie in the dorsolateral columns of spinal segments c7 and c8 and supply the flexor muscles of the forepaw were axotomized by cutting and removing part of the median and ulnar nerves above the elbow. the number and position of cell bodies with axons in these nerves were confirmed by retrograde labelling of the cut axons with horseradish peroxidase. the ability of these neuron ... | 1991 | 1769343 |
| characterization of the human gene for a newly discovered carbonic anhydrase, ca vii, and its localization to chromosome 16. | six carbonic anhydrase (ca) isozymes (ca i-vi) in mammals and other amniotes have been described. we have isolated an additional ca gene from a human genomic library and designated its putative product carbonic anhydrase vii (ca vii). the gene is approximately 10 kb long and contains seven exons and six introns found at positions identical to those determined for the previously described ca i, ca ii, and ca iii genes. the finding of a 17-bp gt-rich segment in a position 28 bp downstream of the p ... | 1991 | 1783392 |
| l3t4+ t cells able to mediate parasite-specific delayed-type hypersensitivity play a role in the pathology of experimental chagas' disease. | during the chronic phase of infection with the parasite trypanosoma cruzi, mice develop inflammatory lesions in the heart and skeletal muscles, as well as in peripheral nerves and the liver. we demonstrated the presence, in the blood of chronically infected mice, of l3t4+ t cells able to transfer a specific t. cruzi delayed-type hypersensitivity (dth) reaction. transfer of the chronic inflammatory lesions was obtained by injecting lyt-2+-depleted lymphocytes from either lymph node or blood of in ... | 1987 | 2440690 |
| intraretinal transplantation for rod-cell replacement in light-damaged retinas. | blindness from retinal disease is often the consequence of extensive damage to the photoreceptor cell population, while other cell types which form the neural retina are relatively spared. in this setting, transplantation of photoreceptor cells could offer hope for the restoration of some degree of visual function. we tested the feasibility of this approach by transplanting immature retinal cells into the eyes of adult rats affected by late stage phototoxic retinopathy, which are almost totally ... | 1989 | 2519517 |
| the dominant substrate of protein kinase c in the extracts of pig granulocytes is a 38 kda ca2+/membrane binding protein. | in the crude extracts of pig granulocytes the dominant substrate of endogenous protein kinase c was a 38 kda protein. this protein was found in the cytosolic extract when the cells were sonicated in the presence of egta but it was bound to the membrane fraction when the cells were sonicated in the presence of ca2+. the phosphorylation of the 38 kda protein was absolutely ca2+/phospholipid dependent. the behaviour of this protein kinase c substrate indicated that it was a lipocortin. | 1989 | 2532838 |
| an alternative method for the isolation of ns-1 hybridomas using cholesterol auxotrophy of ns-1 mouse myeloma cells. | we have used the cholesterol auxotrophy of ns-1 mouse myeloma cells as the basis for selecting ns-1 hybridomas. the outgrowth of nascent ns-1 hybridomas in cholesterol-free serum-free medium was 3- to 9-fold more efficient than that in hat medium and resulted in 3- to 13-times as many antigen-reactive hybridoma wells. this method of hybridoma selection can be applied with any sterol-dependent parent cell line. hybridomas established under serum-free culture conditions were growth inhibited by fe ... | 1989 | 2732203 |
| levels of airborne man-made mineral fibres in dwellings in the uk: results of a preliminary survey. | levels of airborne man-made mineral fibres (mmmf) were measured during the insulation of lofts and after the disturbance of the insulation wools. transmission electron microscopy was used for the analysis. generally, the personal samples showed fibre levels of up to 0.7 f/ml, whereas static samples showed fibre levels of 0.05 f/ml in the lofts. little contamination of living space occurred during these operations. | 1989 | 2744831 |
| inhalation teratology study on hexachloro-1,3-butadiene in rats. | pregnant rats were exposed to 0, 2, 5, 10 or 15 ppm hexachloro-1,3-butadiene (hcbd) 6 h/d during days 6-20 of gestation. maternal reproduction and fetal parameters were evaluated on gestational day 21. a significant reduction in maternal weight gain and in fetal body weight occurred at 15 ppm. the incidences of external, visceral and skeletal alterations were not significantly increased in any of the hcbd-exposed groups. it is concluded that exposure of pregnant rats to hcbd by inhalation of con ... | 1989 | 2749768 |
| coexistence of neuronal messengers--an overview. | | 1986 | 2882559 |
| ryanodine: its possible mechanism of action in the caffeine-sensitive calcium store of smooth muscle. | the caffeine-sensitive intracellular ca store was characterized and the mechanism of action of ryanodine in the store was studied using k-depolarized guinea-pig taenia caecum. (1) after incubation of the preparation with cacl2 (ca loading), caffeine was applied in ca-deprived medium, to produce a transient contraction and to monitor the amount of the stored ca. as duration of ca deprivation was prolonged, the amplitude of the caffeine-induced contraction was decreased. when ryanodine was applied ... | 1988 | 3174395 |
| differential regulation of amyloid-beta-protein mrna expression within hippocampal neuronal subpopulations in alzheimer disease. | we have mapped the neuroanatomical distribution of amyloid-beta-protein mrna within neuronal subpopulations of the hippocampal formation in the cynomolgus monkey (macaca fascicularis), normal aged human, and patients with alzheimer disease. amyloid-beta-protein mrna appears to be expressed in all hippocampal neurons, but at different levels of abundance. in the central nervous system of monkey and normal aged human, image analysis shows that neurons of the dentate gyrus and cornu ammonis fields ... | 1988 | 3277189 |
| spontaneous epithelial tumours of the skin in han: wist- and da/han rats. | | 1986 | 3739445 |
| escherichia coli diarrhoea. | | 1985 | 3912432 |
| [the influence of the trace metal on aconitase activity in human prostate glands]. | | 1967 | 4174993 |
| plasma membranes of the rat liver. isolation and enzymatic characterization of a fraction rich in bile canaliculi. | a method is described for the rapid isolation of a plasma membrane fraction containing a high concentration of intact bile canaliculi from the rat liver. isolated bile canaliculi retain most of the ultrastructural features exhibited in the intact liver cell. the final fraction contains 5'-nucleotidase activity at approximately the same concentration as that in previous preparations of plasma membranes. in the presence of 0.01 m mg(++), 5'-nucleotidase exhibits a double ph optimum at ph values of ... | 1969 | 4304740 |
| the identification of f actin of the pollen tube and protoplast of amaryllis belladonna. | | 1974 | 4609784 |
| [age-related differences in the pharmacokinetic behavior of short-time sulfonamides in rats with special reference to the protein binding rate]. | | 1973 | 4801264 |
| recovery of division ability in ultraviolet-irradiated escherichia coli induced by photoreactivation, photoprotection, and liquid holding treatment. | small doses of ultraviolet light (uv, 265 mmu) cause escherichia coli b to grow into long, multinucleate, nonseptate, filamentous cells. this uv-induced filament formation can be prevented by irradiating with photoprotecting light (335 mmu) prior to uv irradiation, and by irradiating with photoreactivating light (406 mmu), or by liquid holding treatment, after uv irradiation. it is concluded that uv-induced division inhibition in e. coli b is initially induced by repairable lesions in the deoxyr ... | 1967 | 4864408 |
| polymer-linked 6-azauridine 5'-monophosphate, a resin of high bioaffinity to orotidine-5'-phosphate decarboxylase. | condensation of 6-azauridine with ethyl levulinate, followed by saponification or phosphorylation, leads to 2',3'-o-[1-(2-carboxyethyl)ethylidene]-6-azauridine and its 5'-monophosphate. the latter was coupled to 6-aminohexylagarose via its carboxylic group. using the same synthetic route, agarose-linked uridine 5'-monophosphate has been prepared. both polymers show specific binding toward orotidine-5'-monophosphate decarboxylase. the immobilized inhibitor (6-azauridine 5'-monophosphat) binds the ... | 1999 | 94096 |
| familial insulin resistance and acanthosis nigricans. | insulin resistance exists in 0.1% of diabetics having insulin treatment. in addition to diabetics, insulin resistance can also be seen in association with acanthosis nigricans. both conditions become a syndrome that may happen in a family. this is a report of two siblings, a brother and a sister, 14 and 10 years of age, whose parents are cousins, who suffered from diabetes mellitus, acanthosis nigricans, and growth retardation. the insulin therapy until 54 units per day given to the boy and 174 ... | 2007 | 2075024 |
| twenty-seventh world health assembly--2. | | 2015 | 4424977 |
| an erythrocyte membrane-protein anomaly in march haemoglobinuria. | in three patients with march haemoglobinuria a well-defined protein abnormality has been revealed by high-resolution sodium-dodecyl-sulphate/polyacrylamide-gel electrophoresis. | 2000 | 91785 |
| the effect of repeated small doses of radiation on recovery from sub-lethal damage by chinese hamster cells irradiated in the plateau phase of growth. | unfed plateau-phase cells have been irradiated with either single doses or up to ten fractions of x-rays 6 hours apart. the single-dose survival curve had an extrapolation number of 11-4, and the oxygen-enhancement ratio (o.e.r.) was 3-1. cells were exposed to multiple fractions of 200 rad or 150 rad in air and 600 rad or 450 rad in hypoxia. the resulting survival curves did not fit a multi-target, single-hit model of cell survival, being much steeper than that would predict. the curves were exp ... | 2001 | 1083845 |
| projection arteriography and venography: initial clinical results with mr. | motion currently limits the applications of magnetic resonance (mr) angiography in certain regions of the body. to overcome this problem, a series of breath-hold, two-dimensional, flow-compensated gradient-echo images were acquired. these images were then processed by means of the maximum intensity projection algorithm to produce projection angiograms. the method was evaluated in 10 healthy subjects and in 12 patients and validated by comparing conventional angiograms, contrast material-enhanced ... | 2004 | 2748814 |
| projection arteriography and venography: initial clinical results with mr. | motion currently limits the applications of magnetic resonance (mr) angiography in certain regions of the body. to overcome this problem, a series of breath-hold, two-dimensional, flow-compensated gradient-echo images were acquired. these images were then processed by means of the maximum intensity projection algorithm to produce projection angiograms. the method was evaluated in 10 healthy subjects and in 12 patients and validated by comparing conventional angiograms, contrast material-enhanced ... | 2004 | 2748814 |
| evaluation of gastrointestinal function with isotopic tracers. | nuclear medicine is the application of tracer methodology mainly to clinical diagnosis. we use chemical compounds labelled with radioisotopes as tracers. the examinations provide us with the information on regional function of tissues and organs. in this review we describe the nuclear medicine procedures for the diagnosis of gastrointestinal diseases based on our experiences. the emphasis is put on the evaluation of the functional aspect of the gastrointestinal tract. the procedures to be descri ... | 2013 | 3566168 |
| the lillehei-kaster aortic valve prosthesis. long-term results in 273 patients with 1253 patient-years of follow-up. | the lillehei-kaster aortic valve prosthesis was inserted in 313 patients between august 1975 and december 1984. aortic valve replacement alone was done in 193 patients. additional procedures included coronary artery bypass grafting in 62 patients, mitral valve replacement in 22, mitral valvuloplasty in 8, and miscellaneous procedures in 28. the 273 patients discharged from the hospital are the basis of this report. they have been followed up for 1253 patient-years. the range of follow-up is 1 to ... | 2008 | 3259656 |
| [polishing and the surface hardness of amalgams]. | | 2012 | 3461499 |
| [acute pain and practical nursing care. i]. | | 2009 | 2860729 |
| clinical chemistry methodology - past and present. | | 2015 | 4613251 |
| participation of endothelial cells in murine schistosomiasis. | the endothelial cells participate in the morphological events occurring during murine schistosomiasis, taking part in the development of hepatic periovular granuloma. the cells also show an increase in the expression of factor viii-related antigen in the portal vessels and hepatic sinusoids during the infection. endothelial cells are suggested to play an important role in the pathogenesis of the disease and in the balance of the coagulant-anticoagulant mechanisms which favor the intravascular su ... | 2011 | 3150298 |
| the pathology of tumors. part 1: precancerous and pseudomalignant lesions. | | 1998 | 106933 |
| the clinical psychology of lightner witmer: a case study of institutional innovation and intellectual change. | the name lightner witmer is rarely invoked in the historian's litany of psychological saints. neither a grand systematizer nor an ardent experimentalist, the "world's first clinical psychologist" is even dismissed by contemporary clinicians because of his purported failure to achieve for psychologists professional hegemony over the "problem child." yet disciplinary ventures which in joseph ben-david's phrase fail to "take off" represent extremely illuminating indicators of a discipline's shiftin ... | 2004 | 400626 |
| bioaerosols: prevalence and health effects in the indoor environment. | assessing the role of bioaerosols in residence-related symptoms involves (1) determining that symptoms are related to the residence by medical examination and careful questioning, (2) connecting reported symptoms with known or hypothesized effects of bioaerosols, (3) examining the residence for bioaerosol risk factors such as overcrowding/poor ventilation, inappropriate outdoor air intrusion, and dampness/standing water, (4) and finally, if no obvious risk factors are present, air sampling. air ... | 2007 | 2229836 |
| bioaerosols: prevalence and health effects in the indoor environment. | assessing the role of bioaerosols in residence-related symptoms involves (1) determining that symptoms are related to the residence by medical examination and careful questioning, (2) connecting reported symptoms with known or hypothesized effects of bioaerosols, (3) examining the residence for bioaerosol risk factors such as overcrowding/poor ventilation, inappropriate outdoor air intrusion, and dampness/standing water, (4) and finally, if no obvious risk factors are present, air sampling. air ... | 2007 | 2229836 |
| airborne mineral fibre concentrations in an urban area near an asbestos-cement plant. | ambient air concentrations of asbestos and total mineral fibres were measured during the period june-july 1985 at several locations near a large asbestos-cement factory located in the proximity of a northern italian town. measurements of the number and type of fibres were made by means of analytical scanning electron microscopy and energy-dispersive x-ray analysis (sem-edxa), essentially according to the rtm2 reference method of the asbestos international association. total mineral fibre concent ... | 2009 | 2744833 |
| acute butylglycol intoxication: a case report. | a rare case of butylglycol intoxication in a suicide attempt is reported. coma and hypotension were present on admission and severe metabolic acidosis arose subsequently. forced diuresis and haemodialysis led to an uneventful outcome. | 2009 | 2744782 |
| [significance of sudden infant death (sids) for otorhinolaryngology]. | the high frequency of proven extensive infection in the upper respiratory tract, particularly the nose and pharynx, of infants with sids, suggests that the latter may be due to upper airway obstruction. in view of the particular vulnerability of the early infant, the widespread term "common cold" does not seem justified. the constant incidence of sids should stimulate study of the extension and effects of infection of the upper respiratory tract, including careful investigation, follow up and ad ... | 2013 | 3679898 |
| traumatic neuronal injury in vitro is attenuated by nmda antagonists. | pure traumatic neuronal injury was modeled in dispersed neocortical cell cultures derived from fetal mice. a plastic stylet was used to tear the neuronal and glial cell layer; medium oxygen content, ph, and glucose remained unchanged. adjacent to this local disruption, many neurons developed acute swelling and went on to degenerate over the next day, but glia were relatively spared. if the same mechanical insult was delivered in the presence of the n-methyl-d-aspartate (nmda) antagonists dextror ... | 2008 | 2576374 |
| a pilot, double-blind, controlled 1-year trial of prednisolone treatment in primary biliary cirrhosis: hepatic improvement but greater bone loss. | a randomized, double-blind, 1-year pilot study of prednisolone treatment for primary biliary cirrhosis was undertaken. nineteen patients received 30 mg prednisolone per day initially, with a maintenance dose of 10 mg per day. seventeen patients received placebo. the groups were matched for age, menopausal status, hepatic histological stage and bilirubin. treatment was well tolerated without dropouts. two patients receiving prednisolone developed diabetes, one a duodenal ulcer and one depression. ... | 2009 | 2777203 |
| a saved little heart--transposition of great arteries. | | 2005 | 1305656 |
| a model program to teach parenting skills to schizophrenic mothers. | | 2013 | 3666702 |
| utilization of medically-trained birth attendants in rural bangladesh. | using case-control methodology, this study compared the characteristics of women who requested medically-trained birth attendants at home with those who did not, in order to identify constraints to service delivery and suggest program changes to increase service utilization in a rural area of bangladesh. by several different measures, prior contact with medical professionals were much more common among cases than controls, with the greatest differences observed in the frequency of antenatal visi ... | 2004 | 1304774 |
| computer-specific spectacle lens design preference of presbyopic operators. | twenty-nine presbyopic subjects who spent at least 20 hours a week at a video display terminal compared a progressive addition lens designed for this function, with another commonly prescribed task-specific lens. each of the paired lens types was worn for 4 weeks and then compared directly for 1 week. a statistically significant (p < .05) portion of the subjects (76%) preferred the task-specific lenses overall. it also was preferred more frequently for each feature compared, although the differe ... | 2006 | 1403191 |
| functional brain spect: the emergence of a powerful clinical method. | | 2006 | 1403163 |
| major histocompatibility complex class i-restricted activation of cloned t cells by a soluble protein in the absence of accessory cells. | a t-cell clone, 10bk.1, was established from the draining lymph nodes of (b10 x b10.br)f1 mice immunized with ovalbumin (ova) according to standard protocols. upon coculture with the antigen, 10bk.1 cells reacted by production of lymphokines and by proliferation despite the absence of additional antigen-presenting cells. these t cells do not express major histocompatibility complex (mhc) class ii molecules on the cell surface as assessed on the basis of several criteria: by cytofluorometric anal ... | 2009 | 2784568 |
| [mesotheliomas among mechanics of the railways in italy: a current problem]. | asbestos has been used on rolling stock of the italian railways since the 1940's. from the 1950's to the 1970's it was used on a massive scale for the insulation of passenger carriages (up to more than 800 kg per carriage). about 10 years ago, a programme was began to remove asbestos from rolling stock and replace it with glass fibre. we must consider as exposed to the carcinogenic effects of asbestos all mechanics who, during the past years, worked at the major repair workshops (mrw), at the lo ... | 2009 | 2770615 |
| diagnosis and treatment of attention deficit disorder in two general hospital clinics. | in two clinics in military general hospitals, the charts of all children with a presumptive diagnosis of attention deficit disorder who were prescribed psychostimulants (n = 68) were audited to assess the quality of the primary physicians' evaluation and treatment. the audit instrument, constructed by a multidisciplinary team, indicated high interrater reliabilities, high face and concurrent validity, and moderate internal consistency. the audit found that only 51.5 percent of the children being ... | 2009 | 2777226 |
| recombinant erythropoietic growth factors as an alternative to erythrocyte transfusion for patients with "anemia of prematurity". | | 2009 | 2717299 |
| retinal arteriovenous shunts in takayasu disease. | the authors followed up on a series of 24 eyes in 12 patients with takayasu disease in its moderate to advanced stage over the past 10 years. they paid particular attention to arteriovenous shunt formation in the retina. the authors could identify two types of arteriovenous shunts based on rapid sequence fluorescein angiography. in six eyes, arteriovenous shunts had formed at arteriovenous crossings through direct communication of arterial and venous lumen in the midperipheral retina. in 22 eyes ... | 2010 | 2891097 |
| a study to compare the effectiveness of temazepam and a chloral hydrate/hydroxyzine combination in sedating paediatric dental patients. | the study compared the effectiveness of temazepam and a mixture of chloral hydrate and hydroxyzine in sedating 20 young children aged 20 to 60 months (mean age 38.7 months). all the children exhibited negative behaviour during a screening visit and required at least two visits for restorative treatment with the use of sedation. the children were assigned randomly to receive either 50 mg/kg of chloral hydrate with 25 mg of hydroxyzine or 0.3 mg/kg of temazepam for the first visit, and the alterna ... | 2004 | 1304807 |
| the influence of immunosuppression on the prevalence of aseptic bone necrosis after renal transplantation. | | 2007 | 1871842 |
| moderation of morbidity following tonsillectomy and adenoidectomy: a study of awareness under anesthesia. | sixty-seven children between the ages 3 and 10, undergoing tonsillectomy and adenoidectomy, were randomly assigned to one of 3 groups. therapeutic suggestions recited in english (n = 31), french (n = 19), or continuous white noise (n = 18) were repetitively administered by means of earphones in a double blind design. randomization to the english condition was associated with a more favorable outcome with respect to all parameters evaluated by physicians and nurses. however, statistical significa ... | 2004 | 2286510 |
| relationship between severity and clinical importance of symptoms in osteoarthritis. | seventeen patients with primary osteoarthritis of the knee were evaluated with respect to the severity and clinical importance of pain, stiffness and physical function during the conduct of a double-blind randomized controlled trial of flurbiprofen sr versus diclofenac sodium sr using the womac osteoarthritis index. mean importance scores were similar for items within the same dimension as well as between items in different dimensions. in general, low levels of correlation were noted between the ... | 2007 | 1914413 |
| midirs has set up the world's first computer midwifery data base. | | 2006 | 1403180 |
| [biochemistry of glycoconjugates in the studies of cancer metastasis]. | | 2011 | 3295999 |
| [biochemistry of glycoconjugates in the studies of cancer metastasis]. | | 2011 | 3295999 |
| [subungual exostosis of the digits]. | from 1980 to 1990, twenty-two patients with subungual exostosis were treated in pumc hospital and the sixth hospital of beijing. the incidence of subungual exostosis accounted for 4.6% of all bone tumor. post-adolescents and young adults were commonly affected. the female:male ratio was 1.75 to 1. the great toe was the most commonly affected site. radiological findings were diagnostic, and local tumor excision is the treatment of choice. | 1998 | 1299547 |
| prolonged disease-free survival in mopp-resistant hodgkin's disease after treatment with adriamycin, bleomycin, vinblastine and dacarbazine (abvd). | twenty-one patients with advanced hodgkin's disease resistant to mopp (mechlorethamine, vincristine, procarbazine, prednisone) were treated with abvd (adriamycin, bleomycin, vinblastine, dacarbazine). abvd induced complete remission in 13 patients (62%) and partial remission in 2 (9.5%). in particular, complete response to abvd was obtained in 7 of 13 patients who failed to respond to primary mopp chemotherapy. after six cycles, no further therapy was given to patients in complete remission. at ... | 1999 | 93984 |
| [laudatio for professor v. pudel and psychologist j. westenhöfer, winners of the isfe prize 1989]. | | 2008 | 2275708 |
| drug information cards for cancer patients. | | 2009 | 2712028 |
| pseudoaneurysm of the dorsalis pedis artery secondary to nonpenetrating trauma. | | 1998 | 35018 |
| detection of activated ras oncogenes in human thyroid carcinomas. | focus formation following dna transfection of mouse 3t3-vill cells was used to search for the presence of activated oncogenes in human thyroid tumors. oncogenes belonging to the ras family were detected in four out of six thyroid carcinomas (ki-ras in one anaplastic tumor and one follicular moderately differentiated tumor and ha-ras and n-ras in two papillary tumors). normal thyroid tissue samples obtained from two patients, one with an anaplastic tumor and one with a benign adenoma, and samples ... | 1988 | 3283656 |
| perception of self-motion: psychophysical and computational approaches. | | 2013 | 3704035 |
| [a patient's real thought not expressed in words]. | | 2013 | 3648407 |
| [high-resolution computerized tomography and otoradiology]. | | 2014 | 4083440 |
| ethnic differences in congenital malformations. | perinatal deaths and major lethal and non-lethal congenital malformations occurring in this hospital from 1979-82 inclusive were related to the ethnic group of the 15 438 mothers. the highest crude perinatal mortality rates occurred in indian and pakistani populations (18.3 per 1000 and 24.1 per 1000 respectively). the highest incidence of congenital abnormality also occurred in these groups (13.3 per 1000 and 12.8 per 1000 respectively), but there was considerable variation in the distribution ... | 2014 | 4051543 |
| endometrial patterns observed in estrogen-progesterone combination therapy. | | 2015 | 4457476 |
| [natural occurrence of gold glycosides]. | | 2016 | 4879546 |
| angioendothelioma of stewart and treves. | | 2016 | 4865868 |
| [expressions of 2h4 and 4b4 antigens on atl cells]. | we studied the expression of 2h4 and 4b4 on the surfaces of leukemia cells from 17 patients with adult t-cell leukemia (atl) as well as of cells belonging to 2 t-cell lines derived from atl patients. the effects of the supernatants obtained from culture fluids of the atl cells and the t-cell lines on igg production of a human b-cell line, cess cells, were also examined. on the surfaces of the atl cells from 15 out of 17 cases and of the cells of 2 t-cell lines 4b4 obviously existed at higher per ... | 1989 | 2528006 |
| tourette's disorder and associated complex behaviors: a case report. | a case of a man with tourette's disorder associated with obsessive-compulsive disorder, multiple sexual paraphilias, and aggressive behavior is described. treatment with haloperidol led to improvement in the characteristic tics of tourette's disorder as well as to improvement in these three complex-associated behaviors. after haloperidol was discontinued, an exacerbation of tics and the associated behaviors occurred. | 1990 | 2238716 |
| long-chain (sphingoid) bases inhibit multistage carcinogenesis in mouse c3h/10t1/2 cells treated with radiation and phorbol 12-myristate 13-acetate. | sphingosine and other long-chain (sphingoid) bases inhibit protein kinase c, the putative cellular receptor for the tumor promoter phorbol 12-myristate 13-acetate (pma), and exert potent effects on diverse cell functions. we tested the ability of long-chain bases to modulate multistage carcinogenesis in mouse c3h/10t1/2 cells exposed to gamma-rays and pma. sphingosine and sphinganine completely blocked the enhancement of radiation-induced transformation by pma (promotion) and partially suppresse ... | 1991 | 2000399 |
| convergence of visceral and somatic inputs onto subnucleus reticularis dorsalis neurones in the rat medulla. | 1. in anaesthetized rats, recordings were made within the medullary subnucleus reticularis dorsalis (srd) from neurones that exhibited convergence of nociceptive inputs from the entire surface of the body. neurones with total nociceptive convergence responded to supramaximal percutaneous electrical stimuli (2 ms duration) with early and late peaks due to the activation of a delta and c fibres, respectively, no matter which part of the body was stimulated. neurones with partial nociceptive conver ... | 1992 | 1302266 |
| a study of endotoxemia in ulcerative colitis and crohn's disease. i. clinical study. | endotoxin (lipopolysaccharide, lps) and lps antibody in the blood were studied in 61 cases of ulcerative colitis (u.c.) by radioimmunoassay. lysozyme (lzm) concentration was also studied by the turbidimetric method. as a result, it was found that the blood lps value as well as serum lzm concentration reflects the clinical observations. the case of endotoxemia in the active phase group showed a positive correlation between the lps value and lzm concentration. lps antibody which could not be detec ... | 1978 | 150200 |
| solute permeability of the alveolar epithelium in acute hemodynamic pulmonary edema in dogs. | ten anesthetized dogs, 48 h postintravenous 131i-albumin injection, had a segment of lung airspace isolated by a balloon-tipped catheter lodged in a bronchus. an isotonic saline solution containing trace amounts of blue dextran, 125i-albumin, and 57co-cyanocobalamin was instilled into the lung segment. during control periods, lung saline was absorbed at a rate of 0.133% per minute as measured by indicator dilution of blue dextran. only 57co-cyanocobalamin crossed the epithelium. acute hemodynami ... | 1977 | 18023 |
| treatment of bleeding gastroesophageal varices: a report of forty-four cases. | bleeding gastroesophageal varices is associated with a high morbidity and mortality. forty-four cases of bleeding gastroesophageal varices were treated at the department of surgery, universiti kebangsaan malaysia, general hospital, kuala lumpur over four and a half years. thirty-two of them had liver cirrhosis. hepatitis b infection was noted in 13 and alcoholic abuse was present in 14 patients. five patients had associated hepatoma. thirty-four percent had gastric fundal varices and a third of ... | 2003 | 1303478 |
| [the contribution of unit managers in the education of student nurses]. | the contribution of a group of unit managers towards student education, as well as the problems related thereto, has been investigated contextually by means of an explorative descriptive study, utilising structured interviews. the results indicate that, although unit managers have a positive attitude towards student education, they lack insight regarding the programme content, as well as their own informal educational function in the clinical situation. lack of time and inadequate liaison betwee ... | 2001 | 1301290 |
| [the effect of indomethacin and leukinferon on the thromboxane b2 level in the blood plasma of patients with endometrial cancer in the perioperative period]. | the paper discusses the effect of indomethacin, leukinferon as well as their combined effect on blood thromboxane b2 (txb2) level in 40 endometrial cancer patients in the perioperative period. perioperative treatment with indomethacin was followed by a significant decrease in blood txb2 level before surgery and in the postoperative period. treatment with leukinferon exerted similar effect which, however, was less pronounced than that of indomethacin. the effect was most apparent when the two dru ... | 2000 | 1300754 |
| clonidine treatment of acute pancreatitis: report of five cases. | we report five consecutive cases of patients with acute pancreatitis resistant to conventional treatment who improved dramatically with clonidine. all patients showed greatly elevated noradrenaline, adrenaline and cortisol plasma levels (physiological indicators of stress) which fell abruptly upon initiation of clonidine therapy. the clonidine test performed in the patients showed a hyper-response in all, a reaction consistent with uncoping stress situation. therefore, we postulate that stress m ... | 2000 | 1300848 |
| loss of nocturnal decline in blood pressure in diabetic patients with autonomic neuropathy. | we investigated loss of the nocturnal decline in blood pressure (bp) and its mechanism in diabetes mellitus with autonomic neuropathy (anp). bp was measured every 30 min using ambulatory bp recorders in 52 diabetic patients and 11 nondiabetic controls. as an index of autonomic nervous dysfunction, cvrr (the coefficient of variation of the r-r interval on ecgs) and diastolic blood pressure response on standing were measured. plasma volume (pv) was measured with risa. the difference between daytim ... | 1998 | 1299743 |
| advances toward understanding diabetes mellitus. | | 1978 | 1183841 |