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experimental studies on some effects of prostaglandin e2 in acute renal failure.acute renal failure has been produced in rats with oral administration of uranyl nitrate 40 mg/kg of body weight once, and histopathological changes in the kidneys with blood biochemical values were studied by sacrificing them after 36 hours of feeding. prostaglandin e2 in 100 micrograms/kg of body weight was orally administered to another group of rats along with uranyl nitrate 40 mg/kg of body weight once and sacrificed them 36 hours after feeding. it was found that prostaglandin e2 has some p ...19902362130
gut perforation after infection with herpes simplex virus and epstein-barr virus. 19892570271
two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance.insulin receptor complementary dna has been cloned from an insulin-resistant patient with leprechaunism whose receptors exhibited multiple abnormalities in insulin binding. the patient is a compound heterozygote, having inherited two different mutant alleles of the insulin receptor gene. one allele contains a missense mutation encoding the substitution of glutamic acid for lysine at position 460 in the alpha subunit of the receptor. the second allele has a nonsense mutation causing premature cha ...19882834824
redifferentiation and subsequent dedifferentiation of the livers of roosters resulting from acute estrogen challenges.1. histologic and metabolic changes take place in livers of rooster receiving challenges consisting of acute doses of estrone. 2. during initial growth and redifferentiation livers rapidly increase in size by division of hepatocytes within most lobules, changing from cordlike to acinar configurations. 3. no new lobules appear and degeneration of some cells within lobules takes place even as cell divisions predominate. 4. cells within lobules assume secretory features. 5. vitellogenins, very low ...19872887384
human milk-derived lactoferrin inhibits mitogen and alloantigen induced human lymphocyte proliferation.purified lactoferrin (lf), isolated from human milk, was tested for its effect on human t-lymphocyte proliferative responses to phytohemagglutinin (pha) and to alloantigens in mixed lymphocyte culture. lf inhibited proliferation in both assays in a dose-dependent manner. the suppressive effect was not due to lf mediated cytotoxicity since washing cells that had been pre-incubated with lf restored their proliferative activity. lf was most effective in suppressing the pha response when added withi ...19872963123
selective translation initiation on bicistronic simian virus 40 late mrna.we described previously a simian virus 40 (sv40) mutant, psvadl, that was defective in synthesis of the late viral protein vp1. this mutant, which contains a 100-base-pair fragment of adenovirus dna encompassing the major late promoter inserted in the sv40 late promoter region (sv40 nucleotide 294), efficiently synthesizes agnoprotein, a protein encoded by the leader region of the same mrna that encodes vp1. when the agnoprotein aug initiation codon in psvadl was mutated to uug, agnoprotein synt ...19873035232
purification and kinetic characterization of a phenol-sulfating form of phenol sulfotransferase from human brain.the identification of three forms of phenol sulfotransferase (pst) in human brain and the subsequent purification and kinetic characterization of a phenol-sulfating form of the enzyme are described. two forms of pst which were capable of conjugating phenol and a third form which sulfated dopamine were resolved from one another using deae-cellulose chromatography. one of the phenol-sulfating forms (p1-pst) was subsequently purified on affi-gel blue and sephacryl s-200, giving a final purification ...19863463246
metastatic nontraumatic clostridium septicum osteomyelitis.nontraumatic clostridial infections are rare, but need to be diagnosed and treated early or high morbidity and mortality rates result. we believe that this is the first reported case of metastatic nontraumatic clostridium septicum osteomyelitis. early treatment with surgical debridement and parenteral antibiotics without hyperbaric oxygen was used. an associated occult rectal malignancy was discovered and treated.19853980945
basic studies on 3', 4'-dideoxykanamycin b. 19734205657
letter: more about vitamin c. 19744431377
[surgical treatment of primary chronic pancreatitis].surgical methods of treatment of chronic alcoholic pancreatitis must be chosen with special reference to the state of the duct and parenchyma of the pancreas. treatment of alcoholic patients should be performed with the participation of psychiatrists.20123424549
ketamine tolerance. 20123255931
[long-term follow-up of vena cava filters: real-time sonography and the native x-ray image].in 16 patients with vena cava filters (12 günther filters, 4 kimray-greenfield filters) a follow-up study was performed by ultrasound and abdominal plain film. ultrasound allows to identify type and location of the filter as well as the entrapment of emboli. abdominal radiography is useful for exact evaluation of changes in filter position. combination of sonography and plain films is considered to be most suitable for follow-up studies of caval filters.20093035643
[measurement of orthodontic appliance force using prototype sensors].in introductory remarks the most important biomechanical principles, which are relevant for the research, and conditions which must be satisfied presented in intraoral measuring of orthodontic forces were pointed out. first the aim of the research was defined, and then the investigation of mechanical properties of acrylics as a material for orthodontic appliances were carried out. the type of strain gauges, bonds and measuring system configurations, as well as measuring amplifiers and recording ...20082635572
[current approaches to immunological diagnosis of autoimmune and immune complex diseases]. 20102974642
oesophageal pain exacerbated by propranolol. 20113113570
incidence and causes of sepsis in glucose-6-phosphate dehydrogenase-deficient newborn infants.to determine the susceptibility to sepsis in newborn infants deficient in glucose-6-phosphate dehydrogenase (g6pd), we screened 33,943 saudi arab infants. deficiency of g6pd was found in 18%. sepsis was determined by the presence of clinical signs of sepsis and confirmed by positive blood cultures. sepsis was documented in 75 infants (2.2/1000). the incidence of sepsis was significantly higher in 6138 g6pd-deficient infants (3.4/1000) than in the 27,805 with normal g6pd activity (1.9/1000; p les ...20092715888
[iq and oligophrenia--a further health myth]. 20124106359
[iq and oligophrenia--a further health myth]. 20124106359
[the newborn infant of the mother with essential arterial hypertension ]. 20133954855
management of pulmonary atresia with intact ventricular septum.infants with pulmonary atresia and intact ventricular septum pose a difficult clinical problem. pulmonary valvotomy has been widely recommended for relief of the right ventricular obstruction, and most infants also have had an aortopulmonary shunt placed to ensure pulmonary blood flow. we have evolved a different approach that includes placement of a right ventricular outflow tract patch initially and continuation of prostaglandin e1 infusion postoperatively until the need for a shunt can be det ...20133762200
vitamin b absorption in intestinal diseases (coeliac disease, dermatitis herpetiformis, ulcerative colitis, crohn's disease, jejuno-ileal shunting). 20154530459
non-synaptic release from dense-cored vesicles occurs at all terminal types in crayfish neuropile.in the crayfish neuropile, dense-cored vesicles (dcv) have been found in chemical terminals, mixed in with round or pleomorphic agranular synaptic vesicles, as well as in electrical terminals and neurohemal endings. dcv release their content at unspecialized non-synaptic sites. the simultaneous exocytosis of dcv and synaptic vesicles seems to be the rule in chemical terminals. dcv in specific terminals suggest non-synaptic communication. in chemical and electrical terminals, the content of dcv c ...20092702493
[ameloblastic fibroma: clinico-pathologic analysis]. 20113150331
photodynamic therapy--lots of questions but presently few answers. 20113193473
[operative management of esophageal perforations]. 20144017775
aids: not the only infectious killer. 20092761978
language-specific and language-general in developing syntax. 20133745338
the phenothiazines. 20154612601
surgical treatment of acute, massive lung embolism. results and follow-up.between 1970 and 1984 the diagnosis of acute, massive lung embolism was made 30 times in our department. in 29 patients the clinical diagnosis was correct and a trendelenburg operation under extra-corporeal circulation was performed. in 18 cases there was an operation in the immediate preoperative course. in 1 case there was a combination of operation and the use of contraceptives. 3 cases were immobilized by a plaster of paris cast. in 4 cases the use of oral contraceptives and in 3 patients th ...20133716720
immediate reconstruction after mastectomy: team approach.a review of 198 cases of breast reconstruction done at the time of mastectomy for carcinoma of the breast shows an extremely low morbidity. the technique of using a tissue-expander prosthesis enables immediate breast reconstruction without any fear of impairing prognosis, of spreading disease, or of impeding adjuvant therapy.20082398784
appearance of nerve growth factor receptors on cultured neural crest cells.light microscopic radioautography of differentiating quail neural crest cultures (1 to 2 weeks after explanation) incubated with iodine-125-labeled nerve growth factor (125i-ngf) revealed that approximately 35% of the cells bound ngf. the binding was specific and saturable; it was blocked by an excess of nonradioactive ngf, and was not detected following incubation with biologically inactive 125i-ngf. in addition, the binding did not appear to be blocked or diminished by insulin. cell cultures p ...20102996958
[clinical efficacy of selective phototherapy of psoriasis patients]. 20144090681
[nsf's extraordinary national assembly: marathon run with exciting final spurt]. 20071863510
light microscopy of indian ink preparations of fibrillated cartilage. 20144117785
cell surface heparan sulphate implicated in haemopoietic growth factor signalling. 20102978375
[diagnostic value of sonography, computerized tomography and lymphography in malignant lymphoma]. 20143894181
[application of professor machtou's compactors]. 20123482391
how it all started: new zealand's first open heart operation. 20092671838
proteolytic modification of rat prolactin by subcellular fractions of the lactating rat mammary gland.the current study explored prolactin proteolysis by rat lactating mammary gland. 125i-labelled rat prolactin was incubated with tissue fractions of lactating mammary gland and the extent of prolactin degradation and fragment formation was visualized and densitometrically quantitated from autoradiographs derived from sds-polyacrylamide gel electrophoresis under reducing conditions. at ph 4.5, the 25 000 x g pellet of mammary gland converted intact prolactin (23 kda band) to proteolytic fragments ...19863754158
[study on prostaglandin e involved in tooth movement--immunohistochemical observation]. 19873475379
iodine in contrast agents and skin disinfectants is the major cause for hypothyroidism in premature infants during intensive care.in 51 sick newborns the influence of two different nonionic, iodine-containing contrast agents, amipaque (group 1) and omnipaque (group 2) and of long-term treatment with polyvinylpyrrolidone-iodine (pvp-i) (group 3) on thyroid function was studied. in the dose given, freshly dissolved amipaque releases roughly 100 micrograms 'free' iodide/kg body weight; this release may be even higher in the solubilized agent omnipaque because of increased breakdown. urinary iodine excretion was elevated in al ...19873447940
sulfite oxidase from chicken liver. the role of imidazole and carboxyl groups for the reaction with cytochrome c.oxidation of sulfite to sulfate by sulfite oxidase is inhibited when the enzyme is treated with reagents known to modify imidazole and carboxyl groups. modification inhibits the oxidation of sulfite by the physiological electron acceptor cytochrome c, but not by the artificial acceptor ferricyanide. this indicates interference with reaction steps that follow the oxidation of sulfite by the enzyme's molybdenum cofactor. reaction with diethylpyrocarbonate modifies ten histidines per enzyme monomer ...19863019695
sulfite oxidase from chicken liver. the role of imidazole and carboxyl groups for the reaction with cytochrome c.oxidation of sulfite to sulfate by sulfite oxidase is inhibited when the enzyme is treated with reagents known to modify imidazole and carboxyl groups. modification inhibits the oxidation of sulfite by the physiological electron acceptor cytochrome c, but not by the artificial acceptor ferricyanide. this indicates interference with reaction steps that follow the oxidation of sulfite by the enzyme's molybdenum cofactor. reaction with diethylpyrocarbonate modifies ten histidines per enzyme monomer ...19863019695
genetic relatedness of the kemerovo serogroup viruses: i. rna-rna blot hybridization and gene reassortment in vitro of the kemerovo serocomplex.the dsrna profiles of the czechoslovakian and siberian serotypes of the kemerovo serocomplex viruses examined were similar in agarose, while their dsrna profiles were distinct in polyacrylamide gel. blot hybridization studies of the kemerovo serocomplex viruses demonstrated that the genes were highly conserved among the members within each type, but not between types. gene reassortment in vitro was demonstrated among selected pairs of the kemerovo serocomplex viruses by intra- and inter-typic cr ...19882904730
effect of cck antagonists cr 1409 and cr 1505 on rat pancreatic exocrine secretion in vivo.the action of cholecystokinin (cck) antagonists cr 1409 and cr 1505 on pancreatic exocrine secretion stimulated by exogenous and endogenous cck was studied in vivo in anesthetized rats, and compared with proglumide. intravenous administration of cr 1409 and cr 1505 in graded doses between 0.04 and 25 mg/kg/h resulted in a dose-dependent inhibition in pancreatic juice volume and amylase output stimulated by intravenous infusion of cck-8 in a dose of 0.06 microgram/kg/h. cr 1409 is 1,000 times and ...19892813333
effect of cck antagonists cr 1409 and cr 1505 on rat pancreatic exocrine secretion in vivo.the action of cholecystokinin (cck) antagonists cr 1409 and cr 1505 on pancreatic exocrine secretion stimulated by exogenous and endogenous cck was studied in vivo in anesthetized rats, and compared with proglumide. intravenous administration of cr 1409 and cr 1505 in graded doses between 0.04 and 25 mg/kg/h resulted in a dose-dependent inhibition in pancreatic juice volume and amylase output stimulated by intravenous infusion of cck-8 in a dose of 0.06 microgram/kg/h. cr 1409 is 1,000 times and ...19892813333
effects of maternal undernutrition and exercise on glucose kinetics in fetal sheep.fetal glucose kinetics were measured using a combination of isotope-dilution and fick-principle methodology in single-pregnant ewes which were either well-fed throughout, or fed at 0.3-0.4 predicted energy requirement for 7-21 d during late pregnancy. all ewes were studied while standing at rest and then while walking on a treadmill at 0.7 m/s on a 10 degree slope for 60 min. underfed ewes suffered major decreases in fetal total disposal rate, fetal-placental transfer and umbilical net uptake of ...19902223747
effects of maternal undernutrition and exercise on glucose kinetics in fetal sheep.fetal glucose kinetics were measured using a combination of isotope-dilution and fick-principle methodology in single-pregnant ewes which were either well-fed throughout, or fed at 0.3-0.4 predicted energy requirement for 7-21 d during late pregnancy. all ewes were studied while standing at rest and then while walking on a treadmill at 0.7 m/s on a 10 degree slope for 60 min. underfed ewes suffered major decreases in fetal total disposal rate, fetal-placental transfer and umbilical net uptake of ...19902223747
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